{"meta":{"query_hash":"39e2a9d6e42c","filters":{"topic":"Drug-Induced Hepatotoxicity and Protection"},"cohort_total":631,"direct_labels_cover":3,"predictions_cover":631,"exported":631,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/39e2a9d6e42c","api":"https://metacan.xera.ac/api/v1/cohort?topic=Drug-Induced+Hepatotoxicity+and+Protection"},"results":[{"id":"W1154654422","doi":"10.1016/j.tiv.2015.08.012","title":"Metabolomics analysis of the toxicity pathways of triphenyl phosphate in HepaRG cells and comparison to oxidative stress mechanisms caused by acetaminophen","year":2015,"lang":"en","type":"article","venue":"Toxicology in Vitro","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Universiteit Antwerpen; Fonds Wetenschappelijk Onderzoek; McGill University","keywords":"Triphenyl phosphate; Toxicant; Chemistry; Toxicity; Metabolomics; Acetaminophen; Oxidative stress; Tandem mass spectrometry; Chromatography; Liquid chromatography–mass spectrometry; Exhaled breath condensate; Metabolite; In vitro; Pharmacology; Biochemistry; Mass spectrometry; Biology; Organic chemistry","score_opus":0.1015442637743607,"score_gpt":0.3700941118172135,"score_spread":0.2685498480428528,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1154654422","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995709,0.00034033007,0.0007543004,0.00031094736,0.000661919,0.001155409,0.00076850713,0.000024003188,0.00027555943],"genre_scores_gemma":[0.99850154,0.00006326844,0.00045738183,0.0007135854,0.000020008072,0.00012724016,0.000033475957,0.000016328502,0.00006718344],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9960895,0.0017172082,0.00093807216,0.00048471068,0.0002433264,0.00052718626],"domain_scores_gemma":[0.9982005,0.0005604759,0.00052943744,0.00034434212,0.00012822248,0.0002370366],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0019945053,0.00031396802,0.0012109195,0.00054165075,0.00009019674,0.000009273947,0.00046844193,0.0006869092,0.00007288143],"category_scores_gemma":[0.00023956987,0.00027966258,0.00015037174,0.0017354012,0.00031230238,0.00011973987,0.00025561458,0.0009429753,0.0000054773504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011664863,0.0010474013,0.018719222,0.00003437017,0.0005351777,0.0000056733743,0.005253168,0.008684477,0.96205586,0.00050729426,0.00014747962,0.0018433941],"study_design_scores_gemma":[0.0024504699,0.00028650212,0.0077343276,0.0000112988655,0.0005757272,9.4448586e-7,0.00094725855,0.012608705,0.97383887,0.00081341475,0.00049044023,0.00024201752],"about_ca_topic_score_codex":0.0003954672,"about_ca_topic_score_gemma":0.0017204562,"teacher_disagreement_score":0.011783039,"about_ca_system_score_codex":0.00022672409,"about_ca_system_score_gemma":0.00014159214,"threshold_uncertainty_score":0.99996555},"labels":[],"label_agreement":null},{"id":"W1433280094","doi":"10.2147/jpr.s79578","title":"Comparison of single-dose and multiple-dose pharmacokinetics between two formulations of hydrocodone bitartrate/acetaminophen: immediate-release versus biphasic immediate- release/extended release","year":2015,"lang":"en","type":"article","venue":"Journal of Pain Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Mallinckrodt Pharmaceuticals","keywords":"Medicine; Pharmacokinetics; Acetaminophen; Hydrocodone; Anesthesia; Crossover study; Adverse effect; Immediate release; Pharmacology; Cmax; Internal medicine","score_opus":0.4175252243474053,"score_gpt":0.5200186150703774,"score_spread":0.10249339072297209,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1433280094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938956,0.0017201529,0.00058393006,0.0013873692,0.0009859187,0.00096527295,0.0001367353,0.000028670365,0.0002963466],"genre_scores_gemma":[0.99765617,0.00045678997,0.00076580554,0.00008104324,0.0008266108,0.000021181648,0.00004775093,0.00005460752,0.000090061956],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99106336,0.004615453,0.001792161,0.00037093335,0.00130813,0.00084993656],"domain_scores_gemma":[0.9896329,0.0059270207,0.0011796388,0.0003289745,0.0017487156,0.0011827622],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.011652945,0.00036504728,0.0009831806,0.0010806435,0.0003435975,0.000040923336,0.0005159852,0.0004948741,0.00010296315],"category_scores_gemma":[0.0044207973,0.00034750288,0.00025186088,0.0011253806,0.00076953473,0.00042266728,0.0001912604,0.0029432043,0.000022768703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.022268958,0.004613513,0.15676294,0.0008411485,0.0013651022,0.0002605057,0.005509537,0.009263143,0.7162872,0.0002296109,0.007994301,0.07460406],"study_design_scores_gemma":[0.058270108,0.0100147305,0.023063552,0.00038560183,0.0010985619,0.000072668176,0.003511503,0.11417358,0.76913905,0.0028476806,0.016462367,0.0009605895],"about_ca_topic_score_codex":0.00020272576,"about_ca_topic_score_gemma":0.000102095604,"teacher_disagreement_score":0.13369939,"about_ca_system_score_codex":0.00032151022,"about_ca_system_score_gemma":0.00070357136,"threshold_uncertainty_score":0.9998977},"labels":[],"label_agreement":null},{"id":"W1479970182","doi":"","title":"Étude de la toxicité des médicaments posicor et mintezol en culture primaire d'hépatocytes","year":2008,"lang":"fr","type":"article","venue":"Archipelago (Université du Québec à Montréal)","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Molecular biology; Mibefradil; Chemistry; Gynecology; Medicine; Biology; Biochemistry","score_opus":0.029983832107543986,"score_gpt":0.29153589144051206,"score_spread":0.2615520593329681,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1479970182","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96555173,0.017400708,0.0016868158,0.00693031,0.00079712213,0.0009365022,0.00016851058,0.0002696701,0.0062586367],"genre_scores_gemma":[0.97157615,0.018079454,0.0017991589,0.0031897607,0.00042555324,0.000041091036,0.000034595927,0.00008987802,0.0047643706],"study_design_codex":"qualitative","study_design_gemma":"not_applicable","domain_scores_codex":[0.9938707,0.0034090194,0.0004610512,0.00074691745,0.0003616865,0.0011506561],"domain_scores_gemma":[0.99706036,0.0012492425,0.00031119422,0.00041737617,0.00015726812,0.00080456655],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010646243,0.00069644215,0.00064408843,0.00030134522,0.0021487412,0.000057952395,0.00079127157,0.001264544,0.0010625179],"category_scores_gemma":[0.00025540715,0.0007937606,0.00047111075,0.0005093862,0.0017810974,0.0006933704,0.0004594254,0.002817671,0.0005059869],"study_design_candidate":"qualitative","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023395284,0.004226859,0.10315931,0.00053278205,0.0018981941,0.0050037983,0.6564847,0.0017187531,0.07408765,0.0077465023,0.012584946,0.13021697],"study_design_scores_gemma":[0.011467512,0.0021219107,0.19148152,0.0006544288,0.0018048555,0.007525313,0.032994993,0.011792785,0.06426737,0.0050813253,0.66814667,0.0026613441],"about_ca_topic_score_codex":0.09546643,"about_ca_topic_score_gemma":0.08428224,"teacher_disagreement_score":0.6555617,"about_ca_system_score_codex":0.0015292838,"about_ca_system_score_gemma":0.0013247684,"threshold_uncertainty_score":0.99985063},"labels":[],"label_agreement":null},{"id":"W1495505534","doi":"10.1111/j.1742-7843.2011.00823.x","title":"Different Metabolites of Human Hepatotoxic Pyrazolopyrimidine Derivative 5‐<i>n</i>‐Butyl‐Pyrazolo[1,5‐<i>a</i>]Pyrimidine Produced by Human, Rat and Monkey Cytochrome P450 1A2 and Liver Microsomes","year":2011,"lang":"en","type":"article","venue":"Basic & Clinical Pharmacology & Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Microsome; Pyrimidine; Cytochrome P450; Chemistry; Derivative (finance); Cytochrome; Human liver; Pharmacology; Biology; Toxicology; Biochemistry; Metabolism; Enzyme","score_opus":0.1989572485263752,"score_gpt":0.43982564493021914,"score_spread":0.24086839640384394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1495505534","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98854786,0.0035155609,0.000033477765,0.0012569822,0.0022916286,0.0030303875,0.0002415234,0.0003145218,0.00076808216],"genre_scores_gemma":[0.9868413,0.0042440854,0.00021733955,0.006517243,0.00082507223,0.00059519487,0.00010292025,0.00013547845,0.0005213239],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9898926,0.0034076385,0.0026780146,0.0020809942,0.00033017714,0.0016105978],"domain_scores_gemma":[0.9944644,0.002093394,0.0014151135,0.00062686263,0.00039232612,0.0010078767],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0027720344,0.0012130596,0.0026138336,0.00051904714,0.0010836464,0.000035460766,0.00085615064,0.0021911107,0.002731333],"category_scores_gemma":[0.000415998,0.0011495176,0.00044989891,0.00051063264,0.0044495203,0.0004392831,0.00091245555,0.0033337167,0.00006597412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014645552,0.0036690256,0.056272026,0.0002839862,0.0011918592,0.000111212765,0.001112917,0.0000017890947,0.9240346,0.0013448696,0.007132463,0.003380724],"study_design_scores_gemma":[0.007783074,0.0031725953,0.06097893,0.00003635712,0.0013744263,0.00011413111,0.00013137033,0.00016583176,0.9146348,0.001835966,0.008761233,0.0010112468],"about_ca_topic_score_codex":0.0001654455,"about_ca_topic_score_gemma":0.00010648934,"teacher_disagreement_score":0.009399734,"about_ca_system_score_codex":0.00015825975,"about_ca_system_score_gemma":0.0001774426,"threshold_uncertainty_score":0.99910426},"labels":[],"label_agreement":null},{"id":"W1506011547","doi":"10.51847/ksug6dc","title":"10.51847/KsUG6dc","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Indian Council of Medical Research","keywords":"Toxicity; Histology; Acute toxicity; Medicine; Histopathological examination; Histopathology; Physiology; Body weight; Kidney; Pathology; Urine; Pharmacology; Internal medicine","score_opus":0.06509352004722105,"score_gpt":0.34378773438882615,"score_spread":0.27869421434160513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1506011547","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.033453707,0.000051567054,0.0000020851635,0.0007814293,0.000040591392,0.00047842143,0.000037830236,0.00027372362,0.96488065],"genre_scores_gemma":[0.014455673,0.0000030731844,0.00005733616,0.0010271108,0.00038455706,0.000084448555,0.000018889303,0.000027131577,0.9839418],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99860483,0.00029830862,0.00023759599,0.0002966421,0.00013154617,0.00043105407],"domain_scores_gemma":[0.9992743,0.00012390688,0.00004110128,0.00021515804,0.000046300473,0.00029921695],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00050809997,0.00019192672,0.00020139424,0.0001003815,0.00029783743,0.000025307487,0.00023881283,0.0003344427,0.9941191],"category_scores_gemma":[0.000042572665,0.00020195164,0.0000867352,0.00028926728,0.000062020044,0.00011708357,0.00003795804,0.00057857204,0.98375183],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036998602,0.00015253731,0.0000026322352,0.000010346939,0.000048185862,0.000013957694,0.00006510866,0.0004045193,0.003821742,0.000007355377,0.026250916,0.9688527],"study_design_scores_gemma":[0.0005540556,0.00017027438,0.000065842585,0.0000075709686,0.000042078464,0.000022448812,0.0000012956247,0.00081687805,0.0050206226,0.000024608295,0.99302536,0.00024894802],"about_ca_topic_score_codex":0.000028083343,"about_ca_topic_score_gemma":6.449031e-7,"teacher_disagreement_score":0.9686038,"about_ca_system_score_codex":0.000067254354,"about_ca_system_score_gemma":0.000040382463,"threshold_uncertainty_score":0.8235349},"labels":[],"label_agreement":null},{"id":"W1525917419","doi":"","title":"Safe use of acetaminophen.","year":2003,"lang":"en","type":"letter","venue":"PubMed","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Acetaminophen; Drug labeling; Drug packaging; Medicine; Drug industry; Medical emergency; Drug; Pharmacology; Engineering ethics; Engineering","score_opus":0.3260085031997233,"score_gpt":0.3779362571700629,"score_spread":0.05192775397033961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1525917419","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.057207655,0.001584786,0.00028022475,0.7294529,0.032560006,0.013257703,0.0017044706,0.0006268971,0.16332537],"genre_scores_gemma":[0.030030776,0.000414073,0.00020295684,0.9164116,0.003336803,0.0038849954,0.0002558681,0.00012558859,0.045337338],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963938,0.0012474235,0.00061186077,0.00051965093,0.0003120712,0.0009152149],"domain_scores_gemma":[0.9981044,0.0006446355,0.000487701,0.00045238726,0.00013862272,0.00017224386],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00087953,0.00044633687,0.00064362754,0.00029405786,0.00017503204,0.000035396984,0.0003579361,0.0031944509,0.000504563],"category_scores_gemma":[0.0003257057,0.00045874668,0.00029159937,0.0003066306,0.00024644277,0.000200608,0.0000780667,0.005252854,0.00017668307],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061967796,0.000107274514,0.0004771969,0.00030039923,0.00035025858,0.00012457286,0.00006564055,0.000029504026,0.00021079335,0.00005615187,0.8508387,0.14737754],"study_design_scores_gemma":[0.00062078756,0.0000195889,0.0023521464,0.000010121656,0.00027889357,0.000036970596,0.0000042158435,0.00002079169,0.014020747,0.0002826634,0.98192376,0.00042928895],"about_ca_topic_score_codex":0.0000771531,"about_ca_topic_score_gemma":0.000010797612,"teacher_disagreement_score":0.18695872,"about_ca_system_score_codex":0.00017829692,"about_ca_system_score_gemma":0.000084513114,"threshold_uncertainty_score":0.99978644},"labels":[],"label_agreement":null},{"id":"W1529248002","doi":"10.1002/9780470921920.edm128","title":"Idiosyncratic Drug Reactions and the Potential Role of Metabolism","year":2012,"lang":"en","type":"other","venue":"Encyclopedia of Drug Metabolism and Interactions","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Drug; Immune system; Pharmacology; Drug metabolism; Chemistry; Biology; Biochemistry; Computational biology; Immunology","score_opus":0.0213337757189935,"score_gpt":0.33128027111732344,"score_spread":0.30994649539832997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1529248002","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.02814013,0.06124335,0.00010998194,0.001256163,0.0109076435,0.0017581739,0.00066503714,0.00015890622,0.8957606],"genre_scores_gemma":[0.43535772,0.090029866,0.00061368884,0.00029780046,0.0037353672,0.00036243472,0.00007966078,0.00030604313,0.46921742],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973552,0.0010156053,0.0007147219,0.0003489222,0.00021718166,0.00034833135],"domain_scores_gemma":[0.9980121,0.0004891266,0.00084846764,0.00035240478,0.00009715334,0.00020072644],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00087760953,0.00040897832,0.00087718276,0.00044493418,0.00030314652,0.000021981912,0.00023903907,0.00037113432,0.0028481402],"category_scores_gemma":[0.00015141114,0.00031431532,0.00024610545,0.00024979716,0.00067428465,0.000289684,0.00014818148,0.0014251383,0.000047663336],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022816698,0.0031832359,0.00091469206,0.0024018649,0.008204292,0.0000117763675,0.0369113,0.000101049176,0.052185282,0.15870185,0.4461877,0.28891525],"study_design_scores_gemma":[0.0014697241,0.000006649696,0.0005741776,0.000077588345,0.001713769,0.00004171736,0.0010350016,0.00015139638,0.0039014115,0.002151913,0.988592,0.0002846076],"about_ca_topic_score_codex":0.0018043144,"about_ca_topic_score_gemma":0.0002864286,"teacher_disagreement_score":0.54240435,"about_ca_system_score_codex":0.000013154484,"about_ca_system_score_gemma":0.00007586622,"threshold_uncertainty_score":0.9999309},"labels":[],"label_agreement":null},{"id":"W1532771112","doi":"10.1002/9780470516751.ch1","title":"Current <i>in vitro</i> Models to Study Drug‐Induced Liver Injury","year":2007,"lang":"en","type":"other","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"In vitro; Drug; Liver injury; Pharmacology; Computational biology; Computer science; Chemistry; Medicine; Biology; Biochemistry","score_opus":0.19304057827925727,"score_gpt":0.45001545736350973,"score_spread":0.2569748790842524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1532771112","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.096608594,0.0012478535,0.000834153,0.00019332682,0.009051495,0.008182975,0.00022819967,0.00092990376,0.8827235],"genre_scores_gemma":[0.6762802,0.00064069557,0.00036244784,0.0036225547,0.0018579686,0.0007771087,0.000054828033,0.0007125065,0.31569168],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964227,0.00084565073,0.00060958735,0.00089746603,0.00037230752,0.0008522959],"domain_scores_gemma":[0.99867266,0.0001385242,0.000220368,0.0004729732,0.000058060115,0.00043738852],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0015533713,0.00065940036,0.000713094,0.0014849594,0.00015104921,0.000029357669,0.0005215908,0.0010694665,0.006488388],"category_scores_gemma":[0.000019715137,0.0006637039,0.00016478653,0.0007777702,0.000048750444,0.00009995966,0.00023157298,0.0027738279,0.0023344485],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021230024,0.0069735525,0.00035894546,0.00027380127,0.0004866701,0.00024309018,0.00466629,0.00014644004,0.019950187,0.00073855644,0.40140867,0.5626308],"study_design_scores_gemma":[0.0020577994,0.00028798523,0.000039411745,0.00009174834,0.00016845395,0.000006316941,0.00031596716,0.0010431065,0.07444973,0.00026324706,0.9201545,0.0011217155],"about_ca_topic_score_codex":0.0014042413,"about_ca_topic_score_gemma":0.0015458995,"teacher_disagreement_score":0.5796716,"about_ca_system_score_codex":0.00024882876,"about_ca_system_score_gemma":0.000121547535,"threshold_uncertainty_score":0.9995814},"labels":[],"label_agreement":null},{"id":"W1534285412","doi":"10.1002/9781118314968.ch16","title":"Drug‐Induced Liver Disease","year":2012,"lang":"en","type":"other","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"","keywords":"Drug; Disease; Liver disease; Medicine; Pharmacology; Internal medicine","score_opus":0.16295072438022223,"score_gpt":0.41983240002811095,"score_spread":0.2568816756478887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1534285412","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00095887197,0.0021779486,0.0000735616,0.00042605778,0.006079293,0.0011742514,0.00015894845,0.0009416651,0.9880094],"genre_scores_gemma":[0.06790589,0.00067696365,0.00010574307,0.0023863988,0.0031783767,0.00018816449,0.000091455295,0.00047027666,0.92499673],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978776,0.00053584,0.00026255,0.0004551798,0.00020511747,0.0006637323],"domain_scores_gemma":[0.99851483,0.000109807974,0.00021397437,0.0003956975,0.000031857347,0.00073384173],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004455457,0.0004781514,0.00038428372,0.00030450948,0.00018659205,0.000021929807,0.00032037415,0.0011199877,0.1237883],"category_scores_gemma":[0.000038090944,0.00045089138,0.00020689135,0.00017530832,0.00010435821,0.000091152615,0.000114731556,0.0015245798,0.012916397],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010356048,0.00040406527,0.0008319101,0.00026622612,0.00024107908,0.000055766606,0.00016188956,0.0000015144662,0.0009193067,0.0029688634,0.95573944,0.03830635],"study_design_scores_gemma":[0.00054608705,0.000015693458,0.00027195946,0.00004901134,0.00027294035,0.000006443595,0.000013119151,0.000104644394,0.0030670655,0.00014170747,0.9949423,0.00056902104],"about_ca_topic_score_codex":0.00055589934,"about_ca_topic_score_gemma":0.00042115804,"teacher_disagreement_score":0.1108719,"about_ca_system_score_codex":0.00009406004,"about_ca_system_score_gemma":0.000119331016,"threshold_uncertainty_score":0.9997943},"labels":[],"label_agreement":null},{"id":"W1538671317","doi":"10.1503/cmaj.202026","title":"Drug-induced liver injury","year":2021,"lang":"en","type":"article","venue":"Canadian Medical Association Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Liver injury; Asymptomatic; Incidence (geometry); Drug; Medicine; Liver enzyme; Liver failure; Elevated liver enzymes; Presentation (obstetrics); Internal medicine; Gastroenterology; Pharmacology; Surgery; Biology","score_opus":0.06131485434448913,"score_gpt":0.3737498953405191,"score_spread":0.31243504099603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1538671317","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9066318,0.00038078523,0.000054087748,0.050288092,0.009386288,0.00018947157,0.000063266045,0.0000671107,0.032939084],"genre_scores_gemma":[0.95098454,0.00047206323,0.00005631588,0.04144766,0.003401359,0.000013372286,0.000014086777,0.000020680456,0.0035899077],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967342,0.001193313,0.00042848688,0.0002123286,0.0007681451,0.0006635365],"domain_scores_gemma":[0.99670863,0.0002951242,0.00020230941,0.00010299002,0.000559537,0.0021314016],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0029531696,0.00015388048,0.00022467731,0.00016914835,0.0007736347,0.000087889464,0.00023020207,0.0010371244,0.023597132],"category_scores_gemma":[0.0019235733,0.0001649479,0.0001464451,0.00038184633,0.000035139026,0.00018627837,0.000029423927,0.0036104042,0.0013798226],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044399952,0.0002164055,0.03363814,0.000029159946,0.00045406705,0.00425948,0.001494061,0.000014098093,0.0061780442,0.0016921569,0.42991576,0.52206427],"study_design_scores_gemma":[0.0007781473,0.000026269841,0.0041974382,0.000025207937,0.00004230179,0.0006466954,0.00024011193,0.0004789784,0.011438967,0.00043620722,0.98147553,0.00021416803],"about_ca_topic_score_codex":0.0014680527,"about_ca_topic_score_gemma":0.03458187,"teacher_disagreement_score":0.55155975,"about_ca_system_score_codex":0.0012420167,"about_ca_system_score_gemma":0.0043106535,"threshold_uncertainty_score":0.9993977},"labels":[],"label_agreement":null},{"id":"W1547792216","doi":"","title":"REVIEW ARTICLE: APPLICATION OF CELL-BASED ASSAY SYSTEMS FOR THE EARLY SCREENING OF HUMAN DRUG HEPATOTOXICITY IN THE DISCOVERY PHASE OF DRUG DEVELOPMENT","year":2005,"lang":"en","type":"article","venue":"Iranian journal of pharmaceutical research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Phospholipidosis; Drug; Pharmacology; Drug discovery; Drug development; In vivo; Medicine; Bioinformatics; Chemistry; Biology; Biochemistry; Membrane","score_opus":0.3250981567425697,"score_gpt":0.5415104293653934,"score_spread":0.2164122726228237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1547792216","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96724147,0.01164936,0.015469153,0.0024898897,0.00015313663,0.0027731794,0.000049230326,0.000006715198,0.00016784454],"genre_scores_gemma":[0.99766195,0.0011620393,0.0003461925,0.000401912,0.00020991001,0.000156135,0.000003619848,0.000020339654,0.000037899295],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9930967,0.0035502214,0.0016252911,0.00021780242,0.0009905978,0.0005193889],"domain_scores_gemma":[0.9937393,0.0042227977,0.0007753512,0.000280061,0.0007934793,0.00018899654],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.027641622,0.0001936016,0.00055822363,0.00030278962,0.00033748677,0.000030673968,0.0009111034,0.00015020787,0.000055207558],"category_scores_gemma":[0.00052521244,0.00012805128,0.0002464767,0.00079956814,0.00048052956,0.00026543156,0.000069185815,0.001983808,0.000004544803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035235954,0.0048110834,0.010340281,0.006707241,0.00034518947,0.000016087204,0.005332567,0.0036857685,0.86822855,0.0010891438,0.0013773319,0.09454316],"study_design_scores_gemma":[0.005589895,0.00036703658,0.0011061125,0.0011059592,0.0002218064,0.000016373,0.0006262751,0.031541493,0.93008965,0.00011133294,0.029051926,0.00017215073],"about_ca_topic_score_codex":0.00007452804,"about_ca_topic_score_gemma":0.000030917738,"teacher_disagreement_score":0.094371006,"about_ca_system_score_codex":0.00013747274,"about_ca_system_score_gemma":0.00034895528,"threshold_uncertainty_score":0.95800894},"labels":[],"label_agreement":null},{"id":"W15543083","doi":"10.1097/01.mjt.0000140217.48324.e3","title":"乳歯・幼若永久歯の外傷について : 外傷歯治療ガイドラインに沿った処置法について","year":2010,"lang":"en","type":"article","venue":"小児歯科学雑誌","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Computer science","score_opus":0.15179718510928564,"score_gpt":0.46801971934504083,"score_spread":0.3162225342357552,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W15543083","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8929553,0.00007274442,0.00022119803,0.0016550905,0.006606338,0.0004953599,0.000037774742,0.00038947875,0.09756674],"genre_scores_gemma":[0.9902536,0.000047296595,0.0004325555,0.0029427176,0.0012232653,0.00010147237,0.000022582191,0.000038761118,0.004937719],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99822605,0.00024581898,0.00032819592,0.00040962515,0.00019056573,0.00059977197],"domain_scores_gemma":[0.9988592,0.00021684101,0.00012379458,0.000368171,0.0000948038,0.00033719174],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00090043526,0.00026431214,0.00024866426,0.00014760651,0.0005038622,0.000042838932,0.00037004656,0.0007703575,0.0065035303],"category_scores_gemma":[0.00016226213,0.00026307715,0.00014636746,0.0002935911,0.00020369157,0.00021203041,0.00009772042,0.0025520914,0.0031611498],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018101286,0.0004074778,0.009572452,0.00004875918,0.00011062269,0.00006163547,0.0007554187,0.000045921755,0.84183913,0.013865261,0.013616685,0.11949559],"study_design_scores_gemma":[0.0009046247,0.00007114341,0.0041136607,0.0000052091336,0.00004887067,0.00007530379,0.0000404822,0.0008758086,0.22869639,0.0030190088,0.7618219,0.00032754947],"about_ca_topic_score_codex":0.0000977997,"about_ca_topic_score_gemma":0.0002235876,"teacher_disagreement_score":0.74820524,"about_ca_system_score_codex":0.000043217042,"about_ca_system_score_gemma":0.000095820375,"threshold_uncertainty_score":0.9999821},"labels":[],"label_agreement":null},{"id":"W1558138548","doi":"10.18433/j3qg7z","title":"Population Pharmacokinetic and Pharmacodynamic Modeling of Acetazolamide in Peritoneal Dialysis Patients and Healthy Volunteers","year":2013,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Acetazolamide; Pharmacokinetics; Peritoneal dialysis; Medicine; Pharmacodynamics; Dialysis; Population; Pharmacology; Urology; Internal medicine","score_opus":0.10725147621860094,"score_gpt":0.44082042052054327,"score_spread":0.33356894430194234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1558138548","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937654,0.0020777797,0.00013628314,0.001802689,0.001070264,0.00076691614,0.000016745606,0.000024654133,0.00033926955],"genre_scores_gemma":[0.9938951,0.004141768,0.0004196008,0.0012365149,0.00023689879,0.000029788747,0.000003970664,0.000022679034,0.000013678403],"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9958644,0.0009174474,0.001415284,0.00044764465,0.0006512265,0.00070402166],"domain_scores_gemma":[0.9979795,0.00043732882,0.000549517,0.00008151336,0.00032196398,0.0006301554],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0026223473,0.00036017672,0.0006847537,0.00072630483,0.00036109088,0.00007359715,0.00039626335,0.00016901139,0.00048992905],"category_scores_gemma":[0.00019187933,0.0003175706,0.00015355437,0.0008452271,0.00059162173,0.001316045,0.00015668894,0.0014135612,0.000010350586],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009795207,0.00091484346,0.48452955,0.0002977269,0.00017442716,0.00001619463,0.0012838966,0.018644061,0.15497981,0.00012359282,0.000075317,0.33798105],"study_design_scores_gemma":[0.007922907,0.00033253466,0.03133879,0.0000684518,0.00033332474,0.000076268996,0.0002641639,0.9390222,0.017254975,0.00044356327,0.0025210048,0.00042182114],"about_ca_topic_score_codex":0.00076183846,"about_ca_topic_score_gemma":0.00003196597,"teacher_disagreement_score":0.92037815,"about_ca_system_score_codex":0.0001685256,"about_ca_system_score_gemma":0.00012745474,"threshold_uncertainty_score":0.99992764},"labels":[],"label_agreement":null},{"id":"W1560986419","doi":"10.4212/cjhp.v68i3.1458","title":"Intravenous versus Oral Acetaminophen for Pain: Systematic Review of Current Evidence to Support Clinical Decision-Making","year":2015,"lang":"en","type":"review","venue":"The Canadian Journal of Hospital Pharmacy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":171,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Acetaminophen; Adverse effect; Clinical trial; Randomized controlled trial; Pharmacokinetics; Intensive care medicine; Population; MEDLINE; Pharmacology; Internal medicine","score_opus":0.4924016011603563,"score_gpt":0.5759510144702876,"score_spread":0.08354941330993132,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1560986419","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00008295084,0.9783332,0.00036912016,0.0005142509,0.013939544,0.0064348006,0.00024372549,0.000012158095,0.00007028646],"genre_scores_gemma":[0.0034525567,0.99353594,0.00021812237,0.0011257211,0.0013010883,0.00025146262,0.000014339784,0.00007192443,0.000028855695],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9907895,0.004090546,0.0034819765,0.00037026082,0.00054675754,0.00072097656],"domain_scores_gemma":[0.98694384,0.0065605515,0.0031940534,0.0004992867,0.0013667076,0.0014355761],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.02579899,0.00058460695,0.0035972013,0.0004148926,0.0003811354,0.00007325298,0.0018852162,0.00037374094,0.0002759142],"category_scores_gemma":[0.013859375,0.0004035665,0.0014667378,0.0005992331,0.0002576739,0.00026135836,0.00009976511,0.0027663277,0.00012104417],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017037979,0.000088726665,0.000006431282,0.3116187,0.00067771017,0.000070586124,0.00024924675,0.000005897416,1.03569064e-7,0.00003782333,0.01637738,0.67069703],"study_design_scores_gemma":[0.00071279577,0.0015238649,5.1154757e-7,0.3390349,0.00580189,0.00012051793,0.000024634892,0.000019475647,0.0000025780114,0.00017025456,0.65224916,0.00033946123],"about_ca_topic_score_codex":0.0001428173,"about_ca_topic_score_gemma":0.00073847035,"teacher_disagreement_score":0.6703575,"about_ca_system_score_codex":0.001018837,"about_ca_system_score_gemma":0.008588589,"threshold_uncertainty_score":0.99984163},"labels":[],"label_agreement":null},{"id":"W1574954167","doi":"10.1155/2009/503916","title":"Clozapine-Induced Fatal Fulminant Hepatic Failure: A Case Report","year":2009,"lang":"en","type":"article","venue":"Canadian Journal of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Fulminant hepatic failure; Medicine; Clozapine; Asymptomatic; Fulminant; Fulminant hepatitis; Hepatic encephalopathy; Encephalopathy; Liver function; Liver function tests; Internal medicine; Gastroenterology; Hepatitis; Toxic hepatitis; Liver disease; Viral hepatitis; Liver injury; Schizophrenia (object-oriented programming); Liver transplantation; Cirrhosis; Psychiatry","score_opus":0.07044263877669488,"score_gpt":0.36412874148474683,"score_spread":0.29368610270805195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1574954167","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98865175,0.0001265664,0.000551366,0.0073780827,0.0025287406,0.0002720926,0.000029208633,0.000019368466,0.00044279828],"genre_scores_gemma":[0.9941239,0.000023123093,0.0003306881,0.004706643,0.0006679642,0.000006952226,0.000009080548,0.000018527027,0.00011312036],"study_design_codex":"case_report","study_design_gemma":"case_report","domain_scores_codex":[0.9972624,0.0006286868,0.00087269803,0.00025978402,0.00013160931,0.0008448172],"domain_scores_gemma":[0.99757254,0.00007078831,0.00060691684,0.00023552038,0.0002606487,0.001253612],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012394062,0.00026772136,0.00050892145,0.00054501335,0.00038137453,0.000033243337,0.00030530975,0.00042648448,0.00043453896],"category_scores_gemma":[0.0002559103,0.00026227583,0.00022688118,0.00019384756,0.00015244157,0.0002257636,0.000014999558,0.0016137202,0.000044632205],"study_design_candidate":"case_report","study_design_consensus":"case_report","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001956847,0.00033463739,0.045685716,0.000048995957,0.00049558765,0.85568607,0.0017989504,0.0002902522,0.04015664,0.00045669085,0.012954968,0.040134653],"study_design_scores_gemma":[0.0032244667,0.004624894,0.005606346,0.0000453024,0.0002501136,0.87427753,0.00025717594,0.0003737235,0.009050253,0.0006221986,0.10139378,0.00027423122],"about_ca_topic_score_codex":0.001469021,"about_ca_topic_score_gemma":0.036357753,"teacher_disagreement_score":0.08843882,"about_ca_system_score_codex":0.00029957676,"about_ca_system_score_gemma":0.0007018247,"threshold_uncertainty_score":0.99998295},"labels":[],"label_agreement":null},{"id":"W1584665511","doi":"10.1111/j.1478-3231.2011.02506.x","title":"Cholestasis induced by Chinese herbal remedy Xia-Ku-Hua-Tan-Pian","year":2011,"lang":"en","type":"letter","venue":"Liver International","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; University Health Network","funders":"","keywords":"Medicine; Jaundice; Traditional medicine; Ursodeoxycholic acid; Cholestasis; Medical prescription; Adverse effect; Internal medicine; Pharmacology","score_opus":0.14200695581368997,"score_gpt":0.40439970035966366,"score_spread":0.2623927445459737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1584665511","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.28556064,0.0007968675,0.0003955242,0.41983438,0.050125185,0.0029487556,0.004734031,0.0010809007,0.23452373],"genre_scores_gemma":[0.3219427,0.0005055909,0.0002143664,0.62607175,0.015578603,0.00039943703,0.003339566,0.00019928341,0.03174874],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99627054,0.00069793774,0.00070999697,0.0009072104,0.0006863223,0.0007279862],"domain_scores_gemma":[0.9982434,0.00027721073,0.0005438639,0.00043144057,0.00028413563,0.00021997742],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.00061217544,0.0007248794,0.0005355139,0.00040355572,0.0003499966,0.00010396919,0.0013016537,0.0030940573,0.012106652],"category_scores_gemma":[0.00014461669,0.00072979974,0.00036498535,0.00026053167,0.00019072248,0.00039088505,0.00027010677,0.0072281933,0.0022543282],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019231108,0.00033421823,0.0019365539,0.000099749515,0.0009376939,0.0003180607,0.0008303752,0.0000040062464,0.0076421816,0.00014118379,0.9723919,0.015171738],"study_design_scores_gemma":[0.0012698355,0.00010925875,0.0013155817,0.000057685622,0.00015794463,0.00010437107,0.000016923652,0.00030900462,0.0086547425,0.0007260362,0.98651046,0.0007681449],"about_ca_topic_score_codex":0.0006343337,"about_ca_topic_score_gemma":0.000102815604,"teacher_disagreement_score":0.20623736,"about_ca_system_score_codex":0.00045961718,"about_ca_system_score_gemma":0.00015061715,"threshold_uncertainty_score":0.9995153},"labels":[],"label_agreement":null},{"id":"W1604155211","doi":"10.1155/2006/498157","title":"“Unintentional” Acetaminophen Overdose on the Rise: Who is Responsible?","year":2006,"lang":"en","type":"article","venue":"Canadian Journal of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Acetaminophen; acetaminophen overdose; Medicine; Business; Pharmacology; Acetylcysteine; Chemistry","score_opus":0.07460523997618103,"score_gpt":0.3436324515942846,"score_spread":0.2690272116181036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1604155211","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96401316,0.00018707222,0.00015265704,0.027490104,0.0017426255,0.00021225285,0.00008944379,0.000009523861,0.006103151],"genre_scores_gemma":[0.98548985,0.000027714073,0.000051862324,0.010858347,0.00061244273,0.000009611942,0.0000037834266,0.000019009725,0.0029273657],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99752903,0.0010619386,0.00048804426,0.00017755406,0.00015395666,0.0005894658],"domain_scores_gemma":[0.99857044,0.0002394468,0.000357372,0.00018774773,0.00022691835,0.00041808342],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0013156851,0.00019431877,0.00029049863,0.00041110342,0.00045486953,0.000036426936,0.00042003303,0.0002813174,0.00247088],"category_scores_gemma":[0.0001423662,0.00015405627,0.00020432529,0.00016472352,0.00037419153,0.00011668878,0.000020421105,0.0014338751,0.00013532533],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006293646,0.00037566436,0.40894043,0.000038807495,0.0007789867,0.0012308339,0.0010664901,0.0020705725,0.018400537,0.03892344,0.51782584,0.0040547377],"study_design_scores_gemma":[0.0031146798,0.0022740534,0.13947183,0.00007315572,0.00018689672,0.0015329048,0.00017205761,0.00051088753,0.0127601605,0.009971566,0.8297001,0.00023170118],"about_ca_topic_score_codex":0.0011241912,"about_ca_topic_score_gemma":0.0105601065,"teacher_disagreement_score":0.31187427,"about_ca_system_score_codex":0.0002521996,"about_ca_system_score_gemma":0.0004838883,"threshold_uncertainty_score":0.998441},"labels":[],"label_agreement":null},{"id":"W1618491062","doi":"10.51847/0l1hc72","title":"10.51847/0L1hc72","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Toxicity; Solanum nigrum; Alkaline phosphatase; Glutathione peroxidase; Antioxidant; Glutathione; Catalase; Superoxide dismutase; Uric acid; Acute toxicity; Pharmacology; Chemistry; Bilirubin; Creatinine; Biochemistry; Biology; Enzyme; Endocrinology; Botany","score_opus":0.06573417172335891,"score_gpt":0.3441372807386639,"score_spread":0.27840310901530496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1618491062","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.032147016,0.000054347784,0.0000020727455,0.00084034464,0.000040382143,0.00048136973,0.00003660479,0.0002780131,0.9661198],"genre_scores_gemma":[0.015053149,0.0000029343291,0.000056095254,0.0010297624,0.0003820399,0.00008610036,0.000018971648,0.000027646041,0.9833433],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986074,0.00029356033,0.0002329598,0.0002945802,0.00013278442,0.00043872008],"domain_scores_gemma":[0.9992802,0.00011658632,0.000039930303,0.00021446326,0.00004607324,0.00030271432],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00049809186,0.00019351242,0.00019944497,0.00010325323,0.00029777558,0.000025490472,0.00023860078,0.00033326293,0.9942008],"category_scores_gemma":[0.000039955892,0.00020381382,0.00008574186,0.00029574844,0.000060483613,0.00012381733,0.00003818437,0.00057845353,0.9829938],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037158743,0.00015575757,0.0000023866187,0.000010464594,0.00004733025,0.000013787479,0.00006687348,0.0004083544,0.0043747774,0.000008355786,0.02487794,0.96966237],"study_design_scores_gemma":[0.00053764455,0.00017090872,0.00006432699,0.0000074886625,0.00004165206,0.000023395518,0.0000013406003,0.00079853984,0.0052563907,0.000022096223,0.992825,0.0002512231],"about_ca_topic_score_codex":0.000026238964,"about_ca_topic_score_gemma":5.9034244e-7,"teacher_disagreement_score":0.96941113,"about_ca_system_score_codex":0.00006924659,"about_ca_system_score_gemma":0.000041029292,"threshold_uncertainty_score":0.83112866},"labels":[],"label_agreement":null},{"id":"W1632487777","doi":"10.1017/cbo9780511919237.012","title":"Hepatic effects","year":2010,"lang":"en","type":"book-chapter","venue":"Cambridge University Press eBooks","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Chemistry","score_opus":0.07234634697679533,"score_gpt":0.3165116791968461,"score_spread":0.24416533222005077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1632487777","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00513707,0.0001184827,0.00020289583,0.000036207413,0.0029305802,0.0012223795,0.00022772588,0.0003448439,0.98977983],"genre_scores_gemma":[0.01878838,0.00018408425,0.00008622451,0.00047908426,0.00054417667,0.0000060849234,0.00006590968,0.000079317906,0.9797667],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99816924,0.00024059118,0.0002532114,0.00062076084,0.0002306653,0.00048550052],"domain_scores_gemma":[0.9982709,0.00036809285,0.0003121628,0.0005039481,0.00014886721,0.00039601055],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00032317903,0.00055332115,0.00055619754,0.00025604886,0.0006072912,0.000031787393,0.0005601227,0.0023682974,0.000074718184],"category_scores_gemma":[0.000034625053,0.0006739326,0.0003285057,0.000013881353,0.00043193513,0.00009807028,0.0003013839,0.0040535405,0.00027389996],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054692343,0.00009155357,0.00002509342,0.00079702627,0.0007478661,0.0013898037,0.00018474346,0.0000048904108,0.021589993,0.9358245,0.016285365,0.02251222],"study_design_scores_gemma":[0.0011292916,0.00010071948,0.000019199264,0.00010130454,0.00059761986,0.00004411801,0.0000050231624,0.0001141999,0.047760125,0.00007593786,0.94941527,0.0006372152],"about_ca_topic_score_codex":0.0001208132,"about_ca_topic_score_gemma":0.000011687835,"teacher_disagreement_score":0.9357486,"about_ca_system_score_codex":0.00023816677,"about_ca_system_score_gemma":0.00015438198,"threshold_uncertainty_score":0.9995712},"labels":[],"label_agreement":null},{"id":"W1708176823","doi":"10.1111/jgh.13070","title":"Preventive use of a hepatoprotectant against anti‐tuberculosis drug‐induced liver injury: A randomized controlled trial","year":2015,"lang":"en","type":"article","venue":"Journal of Gastroenterology and Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute on Governance","funders":"Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China","keywords":"Medicine; Tuberculosis; Internal medicine; Silybum marianum; Relative risk; Confidence interval; Randomized controlled trial; Adverse effect; Liver injury; Meta-analysis; Gastroenterology; Surgery; Traditional medicine; Pathology","score_opus":0.09839126711268883,"score_gpt":0.37293762538595915,"score_spread":0.27454635827327034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1708176823","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99118847,0.00039320916,0.00043502467,0.0011987769,0.003680213,0.00293157,0.000026556429,0.000026217644,0.00011997578],"genre_scores_gemma":[0.99619913,0.0013955033,0.0003286151,0.0013966371,0.00038994697,0.00018945354,0.0000044289795,0.000026199583,0.00007007657],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.98945993,0.007300292,0.002013909,0.00034459858,0.00028702684,0.000594213],"domain_scores_gemma":[0.99492645,0.0012497095,0.0022703537,0.00020628907,0.00091864035,0.0004285297],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00569655,0.0004149663,0.0033802085,0.000623028,0.00016924134,0.000022736629,0.00027562058,0.0007341322,0.00008736729],"category_scores_gemma":[0.0020252652,0.00032236718,0.0007759675,0.00017784632,0.0007373191,0.00037678893,0.00013664729,0.0016855646,0.000008499154],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9610036,0.0009830409,0.02580579,0.000054365923,0.0021185833,0.00017952608,0.0011800815,0.00004126814,0.0061048944,0.00023168424,0.0007335809,0.0015635941],"study_design_scores_gemma":[0.976731,0.0058152163,0.0004611252,0.000068826936,0.0014761282,0.0007151821,0.00016551098,0.003594431,0.008108579,0.00079213036,0.0018268961,0.0002449506],"about_ca_topic_score_codex":0.00010640322,"about_ca_topic_score_gemma":0.00012201034,"teacher_disagreement_score":0.025344664,"about_ca_system_score_codex":0.00010548644,"about_ca_system_score_gemma":0.00029437814,"threshold_uncertainty_score":0.9999228},"labels":[],"label_agreement":null},{"id":"W1730777739","doi":"10.5588/ijtld.14.0829","title":"Three months of weekly rifapentine plus isoniazid is less hepatotoxic than nine months of daily isoniazid for LTBI","year":2015,"lang":"en","type":"article","venue":"The International Journal of Tuberculosis and Lung Disease","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Centers for Disease Control and Prevention Foundation; Sanofi","keywords":"Medicine; Isoniazid; Internal medicine; Rifapentine; Jaundice; Gastroenterology; Body mass index; Vomiting; Latent tuberculosis; Tuberculosis; Pathology","score_opus":0.09286789638970532,"score_gpt":0.3917793239375435,"score_spread":0.29891142754783817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1730777739","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9835833,0.0033599501,0.0012175306,0.00896262,0.001497364,0.0005982114,0.00044787055,0.000012051244,0.00032112253],"genre_scores_gemma":[0.99752766,0.0005768415,0.00015112775,0.0008635276,0.00058626133,0.000038005655,0.000015255633,0.000024155235,0.00021714311],"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9979855,0.00018987675,0.00080544763,0.00020279821,0.0005724581,0.00024395734],"domain_scores_gemma":[0.99736357,0.0003389631,0.00082781585,0.00019243131,0.0009164268,0.00036081465],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00144338,0.00022897382,0.00044049355,0.00020111572,0.00013203533,0.00003824594,0.00063540606,0.00015796867,0.00015778071],"category_scores_gemma":[0.00026387558,0.00017250021,0.0003491488,0.00013048934,0.00020339224,0.00027552422,0.00014077716,0.00046355318,0.0000040474147],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.05258717,0.006680422,0.56990737,0.0014746094,0.014327521,0.000245887,0.013512699,0.012344924,0.10224102,0.007837119,0.09528488,0.12355636],"study_design_scores_gemma":[0.03984933,0.002761768,0.19641922,0.0014560119,0.0071410537,0.00040854994,0.0033606463,0.40018046,0.26897645,0.024464216,0.053163964,0.0018183183],"about_ca_topic_score_codex":0.0002526013,"about_ca_topic_score_gemma":0.000088969726,"teacher_disagreement_score":0.38783553,"about_ca_system_score_codex":0.00013400293,"about_ca_system_score_gemma":0.0002915227,"threshold_uncertainty_score":0.7034354},"labels":[],"label_agreement":null},{"id":"W1770761605","doi":"10.3109/15563650.2015.1066507","title":"External validation of the paracetamol-aminotransferase multiplication product to predict hepatotoxicity from paracetamol overdose","year":2015,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Acetaminophen; Medicine; Drug overdose; Pharmacology; Emergency medicine; Anesthesia; Poison control","score_opus":0.30579097786572024,"score_gpt":0.4852104913882993,"score_spread":0.17941951352257907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1770761605","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.984925,0.0001357107,0.0030153792,0.0030807112,0.005135731,0.0026415563,0.00023603148,0.00014082676,0.00068910996],"genre_scores_gemma":[0.99372315,0.000074452815,0.0008741302,0.003349842,0.0012368999,0.00035494345,0.000043117365,0.00003837653,0.00030509845],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99298424,0.0035950092,0.0015135201,0.000906293,0.000422498,0.0005784388],"domain_scores_gemma":[0.99603957,0.0014788649,0.0005589924,0.0008805687,0.0003723331,0.00066969637],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0036764857,0.00037382508,0.0007388728,0.00011376439,0.0002772219,0.000026089168,0.00080502895,0.0009799809,0.0003511257],"category_scores_gemma":[0.0032902262,0.00031026627,0.0003549831,0.00051909423,0.00054066826,0.00023320453,0.00026700113,0.0017171446,0.00041246373],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033337157,0.003657879,0.6130717,0.00006362933,0.0003450675,0.000021103278,0.0013786866,0.004287139,0.31599382,0.00096178474,0.0036263808,0.05325915],"study_design_scores_gemma":[0.0043010497,0.00086865114,0.22849149,0.000048498627,0.00028907025,0.000024148347,0.000059027698,0.0040703504,0.7190685,0.0034208768,0.03889916,0.00045916717],"about_ca_topic_score_codex":0.0001983395,"about_ca_topic_score_gemma":0.0001067335,"teacher_disagreement_score":0.4030747,"about_ca_system_score_codex":0.00025433223,"about_ca_system_score_gemma":0.00038294072,"threshold_uncertainty_score":0.999935},"labels":[],"label_agreement":null},{"id":"W1775175073","doi":"","title":"Protective Effect of aqueous bark extract of Terminalia Arjuna against Alcohol-Induced Hepato and Nephrotoxicity in Rats","year":2015,"lang":"en","type":"article","venue":"International Journal of Phytomedicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Horizon College and Seminary","funders":"","keywords":"Chemistry; Lipid peroxidation; Pharmacology; Oxidative stress; Nephrotoxicity; Glutathione peroxidase; Glutathione; Superoxide dismutase; Antioxidant; Alkaline phosphatase; Lactate dehydrogenase; Biochemistry; Nitric oxide; Kidney; Endocrinology; Toxicity; Enzyme; Medicine","score_opus":0.11293048487623004,"score_gpt":0.4522981324146948,"score_spread":0.33936764753846477,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1775175073","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99560845,0.00035283327,0.00016747945,0.00045166773,0.0019955123,0.00064890407,0.000022755648,0.000009188925,0.0007432315],"genre_scores_gemma":[0.9989754,0.00008725511,0.00006386667,0.00022531855,0.00058534445,0.000024851017,0.000003960952,0.000014979809,0.000019024634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99745834,0.00067540683,0.00090952066,0.00017706965,0.00057259534,0.00020709482],"domain_scores_gemma":[0.99763215,0.00045023233,0.0009588014,0.000101752,0.0006319903,0.00022506325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0029029227,0.00021214747,0.0006095373,0.00058232015,0.000031030457,0.000008098844,0.00031968963,0.00025953012,0.00004663493],"category_scores_gemma":[0.0007942213,0.00017304646,0.000120263285,0.00025553955,0.00020394535,0.00025482365,0.000065153225,0.0010475968,0.000003494562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005267452,0.0004680686,0.042404912,0.000136879,0.0004081225,0.00046171653,0.0017606638,0.00021668863,0.841927,0.000020610907,0.00019808435,0.10672982],"study_design_scores_gemma":[0.008711768,0.0027422763,0.023470633,0.0005514899,0.0001113468,0.0005140619,0.0002143722,0.0021695257,0.95915735,0.00091475033,0.0012552912,0.00018713844],"about_ca_topic_score_codex":0.00014829841,"about_ca_topic_score_gemma":0.0000595884,"teacher_disagreement_score":0.11723036,"about_ca_system_score_codex":0.00020821972,"about_ca_system_score_gemma":0.00017576625,"threshold_uncertainty_score":0.70566297},"labels":[],"label_agreement":null},{"id":"W1798627149","doi":"10.1139/cjpp-2014-0191","title":"Montelukast reduces sepsis-induced lung and renal injury in rats","year":2014,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Kidney; Creatinine; Malondialdehyde; Internal medicine; Endocrinology; Lung; Blood urea nitrogen; Sepsis; Oxidative stress; Medicine; Acute kidney injury; Chemistry","score_opus":0.05667216612564613,"score_gpt":0.37608712324852667,"score_spread":0.31941495712288054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1798627149","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935652,0.00069867243,0.000012553916,0.0019391541,0.0026285911,0.000259222,0.00002077304,0.00001154705,0.0008642767],"genre_scores_gemma":[0.99537134,0.000350079,0.000049377297,0.003295723,0.0008185509,0.00001881576,0.0000044199955,0.00001909515,0.000072569324],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99702704,0.0014251682,0.00055752473,0.00031248512,0.000066256405,0.00061151775],"domain_scores_gemma":[0.99831265,0.0003871944,0.00032085564,0.00008604161,0.00012434793,0.00076890737],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013771328,0.00026304717,0.00053729623,0.00057102455,0.00037517224,0.000017334854,0.00023166672,0.00062933576,0.0008604331],"category_scores_gemma":[0.00009796187,0.00025698455,0.00007685375,0.00023620827,0.0004498354,0.00022928548,0.000039212093,0.0018151196,0.000011093374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042583494,0.000053559008,0.0048948084,0.000065502296,0.00014142964,0.00006647138,0.0009388231,0.00011357963,0.9753385,0.00039917714,0.0026409784,0.014921292],"study_design_scores_gemma":[0.0028021797,0.0008414266,0.02064594,0.000050408256,0.00019834438,0.00029384228,0.00012459078,0.0022853254,0.92271876,0.004193212,0.04540437,0.00044159105],"about_ca_topic_score_codex":0.0006480655,"about_ca_topic_score_gemma":0.0015645376,"teacher_disagreement_score":0.052619774,"about_ca_system_score_codex":0.00010828181,"about_ca_system_score_gemma":0.00043564764,"threshold_uncertainty_score":0.99998826},"labels":[],"label_agreement":null},{"id":"W1809063911","doi":"10.1089/acm.2014.5066.abstract","title":"Study of NHP-Drug Adverse Reactions (SONAR) in Patients Seeking Mental Health Services","year":2014,"lang":"en","type":"article","venue":"The Journal of Alternative and Complementary Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Mental health; Adverse effect; Download; Psychiatry; Drug reaction; Alternative medicine; Sonar; Traditional medicine; Family medicine; Drug; Pharmacology; World Wide Web; Computer science; Artificial intelligence; Pathology","score_opus":0.10593370158333575,"score_gpt":0.4340229788989095,"score_spread":0.32808927731557375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1809063911","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958773,0.00011946545,0.000037794613,0.002516253,0.0006746077,0.0004868242,0.000014671288,0.0000037920609,0.00026928712],"genre_scores_gemma":[0.9978452,0.0003993979,0.000022510132,0.0014474973,0.000246172,0.0000030300464,0.0000095313735,0.0000064115097,0.00002026904],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9975804,0.0012265859,0.0006651456,0.00009259192,0.00027233508,0.00016293737],"domain_scores_gemma":[0.9987345,0.00026708565,0.0007295957,0.000078865116,0.00009503621,0.00009491497],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002531017,0.00012072927,0.00031065196,0.00017896519,0.00023822719,0.0000019190918,0.00019548963,0.00002240858,0.00016898496],"category_scores_gemma":[0.000009323601,0.00008063431,0.00002690372,0.00013544006,0.00009516502,0.00014311002,0.00006619311,0.00053167716,0.0000012103366],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029826749,0.0030705507,0.7658441,0.00022875212,0.0008045568,0.000010401905,0.18081078,0.00054874393,0.004136062,0.00019654792,0.0012150897,0.040151756],"study_design_scores_gemma":[0.048525587,0.018614467,0.66317886,0.0012656726,0.0005287829,0.000119602504,0.19227016,0.005654088,0.004926976,0.0023161343,0.062175483,0.00042419284],"about_ca_topic_score_codex":0.0025135581,"about_ca_topic_score_gemma":0.001052633,"teacher_disagreement_score":0.10266523,"about_ca_system_score_codex":0.00008145308,"about_ca_system_score_gemma":0.00001774259,"threshold_uncertainty_score":0.37997648},"labels":[],"label_agreement":null},{"id":"W1818019279","doi":"","title":"Clinical pharmacology consultations: consultation requests may be misleading -- an organized approach to drug-induced hepatitis.","year":2003,"lang":"en","type":"article","venue":"PubMed","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Ranitidine; Drug; Hepatitis; Alcoholic hepatitis; Acute hepatitis; Adverse effect; Intensive care medicine; Family medicine; Pharmacology; Internal medicine; Alcoholic liver disease; Cirrhosis","score_opus":0.23180817200563764,"score_gpt":0.4472683330781615,"score_spread":0.21546016107252386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1818019279","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9500476,0.00007591084,0.0009136927,0.0016259128,0.0059046447,0.0048853057,0.00007591693,0.00046435304,0.036006637],"genre_scores_gemma":[0.97964126,0.00015808019,0.0023825003,0.010319938,0.00064619846,0.0048628547,0.00011603551,0.00007377372,0.0017993583],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9925541,0.004121337,0.0010604777,0.00093956944,0.0002915521,0.0010329215],"domain_scores_gemma":[0.9965082,0.0013396315,0.0003661126,0.00032311628,0.0004702372,0.0009927484],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0047383565,0.00041654278,0.00060314283,0.0003460482,0.00068270665,0.0000835428,0.00037825224,0.0007482691,0.000285618],"category_scores_gemma":[0.0025815621,0.00046849452,0.00013868506,0.0009981886,0.0002355642,0.0004798636,0.00005384787,0.0015232929,0.00024586346],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035202552,0.011833631,0.113395385,0.0005334567,0.0024181088,0.0002082503,0.019693345,0.0016577158,0.11848398,0.03281145,0.062158123,0.6332863],"study_design_scores_gemma":[0.021184787,0.0004034849,0.09651522,0.000025219291,0.0010237772,0.00027904622,0.0018275192,0.003052878,0.31736037,0.00226128,0.55354536,0.0025210434],"about_ca_topic_score_codex":0.00012652027,"about_ca_topic_score_gemma":0.00011972894,"teacher_disagreement_score":0.63076526,"about_ca_system_score_codex":0.00030329236,"about_ca_system_score_gemma":0.00024273824,"threshold_uncertainty_score":0.99977666},"labels":[],"label_agreement":null},{"id":"W1825206184","doi":"","title":"Utilisation de la N-acétylcystéine pour le traitement de l’hépatotoxicité induite par un traitement antituberculeux","year":2015,"lang":"fr","type":"article","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Gynecology; Medicine","score_opus":0.13578866451844412,"score_gpt":0.40101926425720136,"score_spread":0.26523059973875723,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1825206184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9100299,0.0029803694,0.018002126,0.014638379,0.0028457923,0.0016993395,0.00014261021,0.00031174943,0.049349748],"genre_scores_gemma":[0.97889966,0.0009367038,0.0045838333,0.006090591,0.0012303545,0.0003287087,0.00008009776,0.00009446124,0.007755575],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9916367,0.0046688085,0.0010157528,0.0007531874,0.00045261584,0.0014729474],"domain_scores_gemma":[0.99727225,0.0005349177,0.00036798138,0.00038342894,0.00025050956,0.0011908808],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0071281954,0.00068731245,0.0006226285,0.00030190856,0.00065680855,0.00018198174,0.00046403572,0.0018905654,0.0023244866],"category_scores_gemma":[0.0003058892,0.00077660236,0.00030258368,0.00059476175,0.0005370687,0.0006237817,0.0001511031,0.0021747032,0.0004358785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013487948,0.009184187,0.025854884,0.0009918346,0.001879371,0.000556018,0.0259404,0.021865137,0.5365002,0.082517676,0.033309024,0.26005247],"study_design_scores_gemma":[0.006790113,0.00046676287,0.006890288,0.00010629482,0.0004364158,0.00042211,0.0019181132,0.052045204,0.49440607,0.010532336,0.4251685,0.00081778003],"about_ca_topic_score_codex":0.0018876945,"about_ca_topic_score_gemma":0.00027040075,"teacher_disagreement_score":0.39185947,"about_ca_system_score_codex":0.001264227,"about_ca_system_score_gemma":0.0019895462,"threshold_uncertainty_score":0.9994685},"labels":[],"label_agreement":null},{"id":"W1856093924","doi":"10.3109/15563650.2015.1104539","title":"Letter in reply to Riggan et al. Re: External validation of the paracetamol-aminotransferase multiplication product to predict hepatotoxicity from paracetamol overdose","year":2015,"lang":"en","type":"letter","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Medicine; Acetaminophen; Pharmacology; Drug overdose; Emergency medicine; Poison control","score_opus":0.23303798016118335,"score_gpt":0.4708702541764115,"score_spread":0.23783227401522813,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1856093924","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.51470506,0.00007337,0.0004174215,0.47477567,0.00479352,0.0042702383,0.0006124831,0.000100610625,0.0002516343],"genre_scores_gemma":[0.3177239,0.000103930186,0.00058753585,0.6767449,0.0030501809,0.00095124944,0.0002630532,0.00009279266,0.00048251706],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.98377323,0.009285732,0.0029050794,0.0021418137,0.0008057255,0.0010883929],"domain_scores_gemma":[0.99298763,0.0031208692,0.0010770775,0.0018389312,0.00044370978,0.00053178484],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.006929008,0.0008627669,0.0017174971,0.00040488678,0.0002373174,0.00005546731,0.0015250882,0.003025984,0.00048928155],"category_scores_gemma":[0.0039939173,0.0007624827,0.0005948328,0.0008795413,0.00052076904,0.0002602813,0.0005208123,0.009476733,0.0005113287],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016778467,0.0012644057,0.03939648,0.00010499038,0.0002523034,0.00014180102,0.0007720915,0.0009589711,0.032214105,0.000019011237,0.9161106,0.007087414],"study_design_scores_gemma":[0.0026545415,0.00070124865,0.024591109,0.00018359031,0.00024570507,0.000021223454,0.000009525405,0.0004393187,0.08971348,0.00067490636,0.8800443,0.00072110293],"about_ca_topic_score_codex":0.0006043675,"about_ca_topic_score_gemma":0.00039713626,"teacher_disagreement_score":0.20196918,"about_ca_system_score_codex":0.0006612218,"about_ca_system_score_gemma":0.000630367,"threshold_uncertainty_score":0.99948263},"labels":[],"label_agreement":null},{"id":"W1866984045","doi":"10.1111/j.1365-2036.2010.04364.x","title":"The effects of paracetamol (acetaminophen) on hepatic tests in patients who chronically abuse alcohol – a randomized study","year":2010,"lang":"en","type":"article","venue":"Alimentary Pharmacology & Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse","keywords":"Medicine; Acetaminophen; Placebo; Internal medicine; Gastroenterology; Alcohol abuse; Hepatitis C; Alcohol; Hepatitis; Hepatitis C virus; Randomized controlled trial; Antipyretic; Liver injury; Anesthesia; Analgesic; Immunology; Psychiatry; Virus; Pathology","score_opus":0.040077401220141355,"score_gpt":0.39511956547649957,"score_spread":0.3550421642563582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1866984045","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9839038,0.00034849448,0.0000043964624,0.00081429246,0.007029716,0.007462128,0.000020903204,0.00008281511,0.0003334108],"genre_scores_gemma":[0.9878865,0.0010292775,0.000034536788,0.009283288,0.00024815268,0.0012249957,0.000020073954,0.000063750296,0.00020941747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99250764,0.0043870206,0.0011566689,0.0006272815,0.00043828133,0.0008831262],"domain_scores_gemma":[0.99185324,0.0066654906,0.0005835579,0.0005205815,0.0001596132,0.00021754343],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0028081804,0.00057826866,0.0010282836,0.0002501176,0.00058661087,0.00003085413,0.0007974702,0.00054776756,0.0002715486],"category_scores_gemma":[0.00002375401,0.000443658,0.00028345213,0.000441065,0.0009097333,0.00018440475,0.00013231466,0.0028450966,0.00009735319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.13583171,0.027606705,0.33752373,0.00029434773,0.023424631,0.00015444455,0.012058464,0.00042468452,0.43236142,0.00044459724,0.00050268753,0.029372578],"study_design_scores_gemma":[0.4271589,0.00580606,0.089264475,0.000082361534,0.012840717,0.000012659794,0.00026026287,0.004454007,0.4477354,0.0007167474,0.010489701,0.0011786956],"about_ca_topic_score_codex":0.000114616254,"about_ca_topic_score_gemma":0.00029288942,"teacher_disagreement_score":0.29132718,"about_ca_system_score_codex":0.00018131257,"about_ca_system_score_gemma":0.00013303352,"threshold_uncertainty_score":0.9998015},"labels":[],"label_agreement":null},{"id":"W1886109374","doi":"","title":"How much did you take? Reviewing acetaminophen toxicity.","year":2015,"lang":"en","type":"article","venue":"PubMed","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"","keywords":"Acetaminophen; Emergency department; Medicine; Medical emergency; Computer science; Anesthesia; Nursing","score_opus":0.3518321429990447,"score_gpt":0.3906698969180923,"score_spread":0.03883775391904759,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1886109374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94976866,0.0020958036,0.00019521565,0.007052741,0.0040725074,0.0023497236,0.000025981295,0.00037836513,0.034061022],"genre_scores_gemma":[0.98584914,0.0002686801,0.0001060925,0.0027421373,0.0010445489,0.0023302573,0.000014268058,0.00003989624,0.007604963],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971995,0.0007739447,0.0003535382,0.0004843456,0.0003101773,0.00087853],"domain_scores_gemma":[0.9984386,0.0001438706,0.00021287602,0.00034798207,0.00015775434,0.0006989494],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0021463549,0.00031071762,0.00041112414,0.00014810577,0.00032580062,0.000114185015,0.00038753034,0.00053535006,0.00005533921],"category_scores_gemma":[0.00066525466,0.00030045232,0.00013311245,0.00042365032,0.00011180733,0.00047839092,0.0001370407,0.001141005,0.00018758254],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029598543,0.0005890925,0.0067407717,0.00019762415,0.00026810722,0.0000739973,0.0018292246,0.000117092226,0.004847626,0.0013543852,0.013505214,0.97018087],"study_design_scores_gemma":[0.0021118387,0.00007476564,0.0063985954,0.000013693973,0.0001527776,0.00004725439,0.0003578208,0.00035289238,0.049648974,0.0012861581,0.9390637,0.00049149495],"about_ca_topic_score_codex":0.000055602824,"about_ca_topic_score_gemma":0.000053506792,"teacher_disagreement_score":0.96968937,"about_ca_system_score_codex":0.00026490583,"about_ca_system_score_gemma":0.000058804144,"threshold_uncertainty_score":0.99994475},"labels":[],"label_agreement":null},{"id":"W1894298692","doi":"10.1111/j.1478-3231.2010.02243.x","title":"Medical and psychiatric outcomes for patients transplanted for acetaminophen-induced acute liver failure: a case-control study","year":2010,"lang":"en","type":"article","venue":"Liver International","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Acetaminophen; Medicine; Liver transplantation; Internal medicine; Liver disease; Chronic liver disease; Antipyretic; Psychosocial; Gastroenterology; Transplantation; Psychiatry; Analgesic; Cirrhosis; Anesthesia","score_opus":0.05303027249316255,"score_gpt":0.39157413652149925,"score_spread":0.3385438640283367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1894298692","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882004,0.000011359822,0.0019852729,0.001116262,0.0046929833,0.0026991873,0.0010577679,0.00006956377,0.00016718659],"genre_scores_gemma":[0.99659103,0.00002088187,0.0007294458,0.0011290269,0.0005276833,0.00069778087,0.00006324974,0.000023631415,0.00021726888],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9985362,0.00015214669,0.00035220117,0.0003856557,0.00027866484,0.00029508065],"domain_scores_gemma":[0.9985089,0.0008052187,0.00013803608,0.00011254498,0.0002301051,0.00020522492],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006385286,0.00022826658,0.0002549859,0.00017170246,0.000360435,0.000038891976,0.0002727226,0.00046542392,0.0007170305],"category_scores_gemma":[0.00020314065,0.00020688956,0.00014640878,0.000076009135,0.00006247051,0.00019243859,0.00003523303,0.0007675381,0.00002189687],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006509446,0.008860366,0.7538348,0.00029395387,0.006925456,0.000930633,0.0065179244,0.000011499081,0.013078329,0.0038405035,0.0025416466,0.19665547],"study_design_scores_gemma":[0.13071974,0.005564733,0.6343585,0.000055138433,0.005077839,0.0025934158,0.0006605516,0.12982835,0.008797297,0.0017758574,0.078167655,0.002400875],"about_ca_topic_score_codex":0.000062428044,"about_ca_topic_score_gemma":0.0007695336,"teacher_disagreement_score":0.19425459,"about_ca_system_score_codex":0.00003613656,"about_ca_system_score_gemma":0.00005714607,"threshold_uncertainty_score":0.84367114},"labels":[],"label_agreement":null},{"id":"W1904157025","doi":"10.3109/15563650.2015.1077968","title":"A descriptive analysis of aspartate and alanine aminotransferase rise and fall following acetaminophen overdose","year":2015,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Medicine; Acetaminophen; Liver transplantation; Interquartile range; Alanine transaminase; Alanine aminotransferase; Internal medicine; Bilirubin; Liver injury; Gastroenterology; Toxicity; Anesthesia; Transplantation","score_opus":0.33005753222987705,"score_gpt":0.49256409586225525,"score_spread":0.1625065636323782,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1904157025","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995402,0.00078074227,0.00043240952,0.00061465055,0.0011583222,0.0005103758,0.00007310087,0.000064352615,0.0009640734],"genre_scores_gemma":[0.9977089,0.00046164688,0.0003923457,0.0009456319,0.00014000719,0.000048194055,0.000018561437,0.000019853953,0.00026481642],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9962652,0.0016697892,0.0008917496,0.0005831279,0.00015035358,0.00043981062],"domain_scores_gemma":[0.99733865,0.0014538828,0.00023999062,0.00023155619,0.00012049907,0.0006153989],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002874194,0.00027142576,0.0010355228,0.000287359,0.00014942477,0.00001809165,0.00017243315,0.00086546503,0.00009092668],"category_scores_gemma":[0.00096251164,0.00026259964,0.00028788793,0.00054458523,0.0006507701,0.00016550429,0.00014451382,0.0009991397,0.00001972719],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029974373,0.0018269434,0.8899907,0.00009101955,0.007997704,0.00029841633,0.0061455346,0.00052547944,0.032060966,0.0030396234,0.0007260959,0.054300122],"study_design_scores_gemma":[0.031553544,0.008231792,0.7371875,0.00007711271,0.023368618,0.00011735654,0.002802359,0.06536907,0.031963438,0.008769367,0.088435896,0.0021239214],"about_ca_topic_score_codex":0.00014857991,"about_ca_topic_score_gemma":0.0004293544,"teacher_disagreement_score":0.15280314,"about_ca_system_score_codex":0.00007867693,"about_ca_system_score_gemma":0.00011339528,"threshold_uncertainty_score":0.9999826},"labels":[],"label_agreement":null},{"id":"W1905757521","doi":"10.1111/1750-3841.12172","title":"Subchronic and Reproductive/Developmental (Screening Level) Toxicity of Complexation Products of Iron Trichloride and Sodium Tartrate (FemTA)","year":2013,"lang":"en","type":"article","venue":"Journal of Food Science","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Intertek (Canada)","funders":"","keywords":"Chemistry; Toxicity; Sodium; No-observed-adverse-effect level; Reproductive toxicity; Urea; Pharmacology; Endocrinology; Biochemistry; Medicine; Organic chemistry","score_opus":0.19945791367372914,"score_gpt":0.38168395513370146,"score_spread":0.18222604145997232,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1905757521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975667,0.00033852574,0.0003823944,0.0007446393,0.00042401068,0.00034562714,0.0000068864138,0.0000063748394,0.00018483945],"genre_scores_gemma":[0.99723274,0.000105061896,0.0024389084,0.000058819598,0.00012453947,0.0000041563453,4.0765923e-7,0.000005262867,0.000030088418],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99846196,0.00017148112,0.0005450497,0.00025509103,0.00032902334,0.00023736824],"domain_scores_gemma":[0.9983783,0.00009708601,0.0007484147,0.000096035044,0.00056494656,0.000115215844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002696335,0.0001218017,0.00027343293,0.00027186502,0.0002646214,0.000026351918,0.00019489486,0.00009153744,0.000029060726],"category_scores_gemma":[0.00046355915,0.000106719395,0.000033201355,0.00053423445,0.00071376294,0.00085001177,0.00008268477,0.00048733258,0.0000012807842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017165752,0.00010809265,0.005642222,0.0000915517,0.000030315518,0.0000013662924,0.0015673864,0.000086255764,0.97269905,0.00021306417,0.00003430822,0.019354723],"study_design_scores_gemma":[0.00078388944,0.00078533014,0.07747931,0.000041286006,0.000032852884,0.00016582217,0.00035935748,0.0006001955,0.91852397,0.0008792056,0.00023904565,0.00010974878],"about_ca_topic_score_codex":0.000036475467,"about_ca_topic_score_gemma":0.000012793664,"teacher_disagreement_score":0.07183709,"about_ca_system_score_codex":0.00007672544,"about_ca_system_score_gemma":0.0003341058,"threshold_uncertainty_score":0.43518907},"labels":[],"label_agreement":null},{"id":"W1913241712","doi":"10.1139/cjpp-2015-0270","title":"Cytoprotective potential of tiron and methyl palmitate against acetaminophen-induced acute liver injury","year":2015,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Tiron; Acetaminophen; Liver injury; Pharmacology; acetaminophen overdose; Oxidative stress; Chemistry; Internal medicine; Medicine; Endocrinology; Biochemistry; Antioxidant; Acetylcysteine; Enzyme; Superoxide","score_opus":0.088655826337044,"score_gpt":0.3690460400562853,"score_spread":0.2803902137192413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1913241712","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99411136,0.0012530128,0.000046152098,0.0006462016,0.0029443137,0.00041479,0.00009688762,0.000011904779,0.00047536826],"genre_scores_gemma":[0.9968991,0.0007568395,0.00014344892,0.0014975165,0.0005533254,0.000019115007,0.000007508314,0.000022818705,0.000100318466],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99715734,0.001320253,0.000565406,0.0003044421,0.000104907136,0.0005476369],"domain_scores_gemma":[0.9976807,0.00020110395,0.000547407,0.000107262014,0.00039775218,0.0010657804],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011621992,0.00029410646,0.0006527764,0.00044790527,0.000296859,0.000010976281,0.0002550804,0.0006806336,0.00043624477],"category_scores_gemma":[0.00008041453,0.00028070234,0.000119372504,0.00021355873,0.0007277709,0.00025285844,0.00006636267,0.0015758832,0.000017358372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011840491,0.00007478655,0.00060809945,0.00008188306,0.0007011513,0.0002656289,0.0017447523,0.000149652,0.9794139,0.00013686111,0.0012479757,0.014391256],"study_design_scores_gemma":[0.004040541,0.001908784,0.0057345266,0.000022726943,0.00072073797,0.00054045295,0.00033271097,0.0008483566,0.9706176,0.0032999697,0.011548324,0.0003852722],"about_ca_topic_score_codex":0.00058975763,"about_ca_topic_score_gemma":0.000315382,"teacher_disagreement_score":0.014005983,"about_ca_system_score_codex":0.00013029238,"about_ca_system_score_gemma":0.00085261284,"threshold_uncertainty_score":0.99996454},"labels":[],"label_agreement":null},{"id":"W1921855332","doi":"10.1155/2000/416705","title":"TNF-alpha but not IL-1alpha are Correlated with PGE<sub>1</sub>-Dependent Protection Against Acute D-Galactosamine-Induced Liver Injury","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Nitric oxide; Proinflammatory cytokine; Liver injury; Galactosamine; Chemistry; Lipopolysaccharide; Tumor necrosis factor alpha; Prostaglandin E; Nitrite; Internal medicine; Pharmacology; Endocrinology; Medicine; Inflammation; Biochemistry; Glucosamine","score_opus":0.04694838448623229,"score_gpt":0.2958973032489456,"score_spread":0.2489489187627133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1921855332","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944143,0.00004423597,0.000259083,0.0016501308,0.0021453986,0.0007890081,0.00023155175,0.00005240484,0.00041383487],"genre_scores_gemma":[0.994534,0.0002308827,0.00004226001,0.0042569204,0.0005700757,0.000053115215,0.000021379225,0.00006574404,0.00022558936],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962377,0.0010343266,0.000855726,0.00044983256,0.00027978086,0.0011426585],"domain_scores_gemma":[0.99718887,0.00006272204,0.00078209065,0.00026951605,0.0003890724,0.001307719],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00082302076,0.0004869417,0.00069893146,0.00071425206,0.00056976604,0.000060778402,0.00045287475,0.0007955265,0.00065527146],"category_scores_gemma":[0.000060272796,0.00046476568,0.00022612512,0.0003067699,0.00029738038,0.00042666777,0.000024213423,0.0031636658,0.00020759665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.020905664,0.00050891115,0.04683809,0.00009185051,0.002106312,0.0068930015,0.0011541997,0.00213166,0.81466424,0.00001811373,0.0025286889,0.10215926],"study_design_scores_gemma":[0.014626439,0.015636703,0.11467637,0.0003621569,0.0014043667,0.015388557,0.0004131558,0.0024998346,0.8130457,0.000089327,0.020656193,0.0012011991],"about_ca_topic_score_codex":0.00087255635,"about_ca_topic_score_gemma":0.025489392,"teacher_disagreement_score":0.100958064,"about_ca_system_score_codex":0.0006294279,"about_ca_system_score_gemma":0.000669812,"threshold_uncertainty_score":0.9997804},"labels":[],"label_agreement":null},{"id":"W1963900110","doi":"10.1592/phco.21.5.513.34501","title":"Colestipol‐Induced Hepatotoxicity","year":2001,"lang":"en","type":"article","venue":"Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Medicine; Gastroenterology; Asymptomatic; Bile acid; Dyslipidemia; Transaminase; Internal medicine; Liver function tests; Liver function; Elevated transaminases; Hepatic function; Liver damage; Alanine transaminase; Chemistry; Biochemistry; Enzyme","score_opus":0.1344406187567093,"score_gpt":0.4416118577038609,"score_spread":0.3071712389471516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1963900110","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98263633,0.006203712,0.00013274567,0.0048379833,0.0033541818,0.0010190712,0.000013922318,0.00010940495,0.0016926486],"genre_scores_gemma":[0.95296896,0.029594984,0.0000330158,0.014524187,0.0020344274,0.00005079353,0.0000028886452,0.00007152976,0.00071921264],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99396497,0.0033581934,0.0011037451,0.00035549543,0.00041468922,0.00080293044],"domain_scores_gemma":[0.9968168,0.0010752758,0.0010086893,0.00024710517,0.00034887227,0.00050323777],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0051136003,0.0005735839,0.00072714326,0.0003997201,0.001556769,0.000055641824,0.0009294161,0.00038561755,0.0034281295],"category_scores_gemma":[0.000026459864,0.00041525663,0.00029866077,0.000513475,0.00062661036,0.00051546295,0.000082864506,0.002830193,0.000049849037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0045775217,0.00087980443,0.006964536,0.000021040067,0.0007842143,0.00012795338,0.0034037028,0.00013841891,0.92277277,0.00021338902,0.01249287,0.04762379],"study_design_scores_gemma":[0.011911219,0.00096632336,0.0018995926,0.000024759789,0.00035048794,0.0014138449,0.00034782058,0.0005637334,0.69212127,0.0023611716,0.2874736,0.0005661925],"about_ca_topic_score_codex":0.00007024024,"about_ca_topic_score_gemma":0.000025316103,"teacher_disagreement_score":0.27498072,"about_ca_system_score_codex":0.00013698192,"about_ca_system_score_gemma":0.00016374303,"threshold_uncertainty_score":0.99982995},"labels":[],"label_agreement":null},{"id":"W1964374974","doi":"10.1016/s0300-483x(02)00581-4","title":"Effects of lipopolysaccharide-stimulated inflammation and pyrazole-mediated hepatocellular injury on mouse hepatic Cyp2a5 expression","year":2002,"lang":"en","type":"article","venue":"Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Lipopolysaccharide; Inflammation; Liver injury; Pyrazole; In vivo; Endoplasmic reticulum; Internal medicine; Chemistry; Pharmacology; Endocrinology; Biology; Immunology; Biochemistry; Medicine","score_opus":0.05539770590853961,"score_gpt":0.3410926601357014,"score_spread":0.2856949542271618,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964374974","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959951,0.00027159,0.00017106727,0.00047554285,0.0007596752,0.0013573355,0.000032865915,0.00023866422,0.00069812965],"genre_scores_gemma":[0.9978561,0.0004731608,0.00009210038,0.0006921108,0.00019023365,0.00018963974,0.000027785101,0.000044717926,0.0004341665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99719226,0.00090466306,0.0006544404,0.0004856103,0.0002238268,0.000539185],"domain_scores_gemma":[0.9978606,0.0011048738,0.0003892709,0.0002730043,0.00010030063,0.00027195024],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005552082,0.0003721545,0.0005492027,0.00039757747,0.00030232844,0.000016389904,0.00022171551,0.001055165,0.00085254706],"category_scores_gemma":[0.0005165022,0.00036506585,0.000099797435,0.00027241488,0.00028524277,0.00020127452,0.00011338085,0.001089527,0.0003341746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005131046,0.0005422724,0.0024705522,0.0002695436,0.0000920418,0.00004175304,0.00079512503,0.0002765229,0.9795119,0.00040348194,0.00039426246,0.014689428],"study_design_scores_gemma":[0.00220666,0.00095155544,0.000439101,0.00005698483,0.000106333515,0.000013730012,0.000022239177,0.03972738,0.9520423,0.00033112807,0.0037763326,0.00032626075],"about_ca_topic_score_codex":0.000046082674,"about_ca_topic_score_gemma":0.000012573238,"teacher_disagreement_score":0.039450858,"about_ca_system_score_codex":0.00010732575,"about_ca_system_score_gemma":0.000028160823,"threshold_uncertainty_score":0.99988014},"labels":[],"label_agreement":null},{"id":"W1966575378","doi":"10.5489/cuaj.1753","title":"Hepatic failure induced by cyproterone acetate: A case report and literature review","year":2014,"lang":"en","type":"article","venue":"Canadian Urological Association Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Soonchunhyang University","keywords":"Cyproterone acetate; Cyproterone; Acute hepatic failure; Medicine; Chemistry; Liver failure; Internal medicine; Hormone; Androgen","score_opus":0.04095737101788247,"score_gpt":0.33716022281680946,"score_spread":0.29620285179892697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966575378","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9232451,0.005499017,0.00013280677,0.06788749,0.0009704298,0.00074778387,0.00011281623,0.0000678759,0.0013367076],"genre_scores_gemma":[0.97401243,0.0022841548,0.00009787076,0.022560436,0.0004722323,0.000047636677,0.00003969401,0.00001553975,0.0004700278],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967663,0.0016361142,0.0005194616,0.00030289555,0.00020540597,0.000569783],"domain_scores_gemma":[0.99787056,0.00026188407,0.0004995681,0.00012564487,0.00025616924,0.0009861927],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0034068772,0.0002256669,0.00036704977,0.00013071219,0.0007971664,0.0001378899,0.00013586857,0.0008624854,0.00058036606],"category_scores_gemma":[0.0018519942,0.00019626625,0.00010067999,0.00030980833,0.00004123122,0.00022031023,0.000024635945,0.0025881617,0.000051937415],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030826946,0.0005839233,0.16359591,0.001406487,0.0015702948,0.1231501,0.0030445205,0.000060966857,0.031276632,0.0012978987,0.40890107,0.26480392],"study_design_scores_gemma":[0.0016514956,0.00044154376,0.0061414465,0.0002748255,0.00030856335,0.15047732,0.000044719858,0.000727596,0.0006455979,0.002041088,0.8366432,0.0006025823],"about_ca_topic_score_codex":0.00037121619,"about_ca_topic_score_gemma":0.001145748,"teacher_disagreement_score":0.42774215,"about_ca_system_score_codex":0.00045204387,"about_ca_system_score_gemma":0.00015825203,"threshold_uncertainty_score":0.9997129},"labels":[],"label_agreement":null},{"id":"W1966820094","doi":"10.3109/15563650.2013.844824","title":"Antidote removal during haemodialysis for massive acetaminophen overdose","year":2013,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; University of Toronto; Public Health Ontario; Queen's University","funders":"Canadian Institutes of Health Research; Pediatric Oncology Group of Ontario","keywords":"Antidote; Acetaminophen; Medicine; acetaminophen overdose; Dialysis; Hemodialysis; Anesthesia; Acetylcysteine; Metabolic acidosis; Lactic acidosis; Acidosis; Surgery; Toxicity; Internal medicine; Chemistry","score_opus":0.2447720098548539,"score_gpt":0.4948595416713628,"score_spread":0.2500875318165089,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966820094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98248154,0.00012625875,0.0007815339,0.0042966264,0.005004529,0.002262489,0.00008955537,0.00025020697,0.004707269],"genre_scores_gemma":[0.9850121,0.0002635488,0.001973715,0.004969333,0.0021127628,0.0007694867,0.000050751823,0.000060350634,0.004787915],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.995363,0.001405279,0.0012084257,0.0008695307,0.00016456965,0.0009891873],"domain_scores_gemma":[0.99573183,0.0025337422,0.00046446003,0.0004669103,0.00027405986,0.00052900094],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0017798472,0.00038775214,0.00088853843,0.00018858655,0.00064583996,0.00005127054,0.0004959294,0.0017888224,0.003766802],"category_scores_gemma":[0.0018327209,0.00038296706,0.00059694063,0.00031051124,0.00057073217,0.0003054656,0.00023225337,0.0016725479,0.0021511817],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004223096,0.004712905,0.074340224,0.0005329189,0.0029424797,0.00043491958,0.000904662,0.0014107196,0.5538449,0.008098995,0.04507706,0.30347708],"study_design_scores_gemma":[0.01692459,0.0020360425,0.15028578,0.00004508893,0.00095182407,0.00025616505,0.00023771066,0.015418102,0.15651281,0.021378959,0.6342298,0.001723145],"about_ca_topic_score_codex":0.000043074713,"about_ca_topic_score_gemma":0.00002921318,"teacher_disagreement_score":0.5891527,"about_ca_system_score_codex":0.00022648634,"about_ca_system_score_gemma":0.00014798873,"threshold_uncertainty_score":0.99986225},"labels":[],"label_agreement":null},{"id":"W1967698420","doi":"10.1016/j.toxlet.2015.04.014","title":"Multiparametric assay using HepaRG cells for predicting drug-induced liver injury","year":2015,"lang":"en","type":"article","venue":"Toxicology Letters","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McGill University","keywords":"Liver injury; Drug; Chemistry; Pharmacology; Medicine","score_opus":0.24991622370066077,"score_gpt":0.431775261419335,"score_spread":0.1818590377186742,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967698420","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.984093,0.000119048964,0.0042810794,0.001594731,0.0064968024,0.0021137334,0.000096050615,0.00035586307,0.0008497056],"genre_scores_gemma":[0.98317385,0.000021313095,0.0036712433,0.011177022,0.0012512918,0.00033090793,0.000022781107,0.000081144855,0.00027043436],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99552834,0.001589867,0.0006804561,0.0007634613,0.00027868577,0.0011592148],"domain_scores_gemma":[0.9968737,0.0016378923,0.00041548294,0.00030632646,0.00020680291,0.0005597917],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0035288113,0.0004779963,0.0005874689,0.0005665624,0.0006243067,0.000050098868,0.00047337532,0.0009443306,0.00014932663],"category_scores_gemma":[0.00087775383,0.00052025914,0.00024336932,0.00068265054,0.0002597824,0.00035195833,0.00016579895,0.001564173,0.00025258475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007326672,0.0004207366,0.0046976437,0.000080903475,0.00023577378,0.000070398695,0.0014661958,0.0033962678,0.9625679,0.00010305936,0.012750126,0.013478323],"study_design_scores_gemma":[0.004555242,0.0004919172,0.00042670913,0.000027556389,0.0003825753,0.00012543604,0.00029005305,0.11055654,0.81473964,0.00021914546,0.06725631,0.0009288875],"about_ca_topic_score_codex":0.00019315931,"about_ca_topic_score_gemma":0.00005264803,"teacher_disagreement_score":0.14782828,"about_ca_system_score_codex":0.00063750194,"about_ca_system_score_gemma":0.00023321148,"threshold_uncertainty_score":0.9997249},"labels":[],"label_agreement":null},{"id":"W1968682431","doi":"10.1007/s40264-014-0185-4","title":"Causality Assessment for Suspected DILI During Clinical Phases of Drug Development","year":2014,"lang":"en","type":"review","venue":"Drug Safety","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Innovative Medicines Initiative","keywords":"Medicine; Clinical trial; Causality (physics); Drug; Expert opinion; Drug development; Intensive care medicine; Pathology; Pharmacology","score_opus":0.2678899825798018,"score_gpt":0.5536385489352086,"score_spread":0.2857485663554068,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968682431","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0069744447,0.9649768,0.0019307034,0.00027281398,0.00887951,0.009601857,0.0014064276,0.00046711476,0.0054903287],"genre_scores_gemma":[0.0057500713,0.98756695,0.0016113163,0.00015569534,0.0012357392,0.0008445147,0.00077950937,0.000102329264,0.0019538715],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9921487,0.0030971647,0.0028479886,0.00089745974,0.00031400807,0.0006947097],"domain_scores_gemma":[0.99399287,0.0033143049,0.00155171,0.00055893353,0.00025077054,0.0003314024],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0063779824,0.0007172409,0.003032881,0.00023484736,0.0006412335,0.000022906876,0.00060560263,0.0010535986,0.0004835438],"category_scores_gemma":[0.0004156435,0.00064985215,0.0010191338,0.0003467387,0.00025362824,0.00009852631,0.00023113185,0.0022682566,0.000060801864],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003316706,0.0010672659,0.00036171626,0.027144793,0.0013382068,0.0000100542975,0.00034047646,0.000015200925,0.000027986967,0.00055544544,0.001466317,0.9673409],"study_design_scores_gemma":[0.0020836755,0.000048686554,0.00034119975,0.0018958487,0.0011715223,0.000014296832,0.000032151154,0.00006687001,0.0010511524,0.00009032192,0.99255186,0.00065239967],"about_ca_topic_score_codex":0.000038334383,"about_ca_topic_score_gemma":0.00012874845,"teacher_disagreement_score":0.9910855,"about_ca_system_score_codex":0.00055489765,"about_ca_system_score_gemma":0.001185687,"threshold_uncertainty_score":0.9995953},"labels":[],"label_agreement":null},{"id":"W1969329034","doi":"10.1002/hep.22044","title":"Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial","year":2007,"lang":"en","type":"article","venue":"Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":133,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Minority Health and Health Disparities; National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Valeant Pharmaceuticals International; University of Colorado School of Medicine, Anschutz Medical Campus; University of Connecticut; Vertex Pharmaceuticals; New England Research Institutes; Virginia Commonwealth University; University of Southern California; National Cancer Institute; National Institute on Alcohol Abuse and Alcoholism; Saint Louis University; Massachusetts General Hospital; GlaxoSmithKline; Bristol-Myers Squibb; Eli Lilly and Company; AstraZeneca; University of Washington","keywords":"Medicine; Cirrhosis; Hepatitis C; Term (time); Internal medicine; Gastroenterology; Antiviral treatment; Virology; Chronic hepatitis; Virus","score_opus":0.13533351589681128,"score_gpt":0.4163967744758667,"score_spread":0.28106325857905545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1969329034","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9895005,0.00043904866,0.00009529473,0.0017474735,0.0024711029,0.0025740752,0.000112156304,0.00012850347,0.0029318454],"genre_scores_gemma":[0.99431634,0.0010869036,0.00005629376,0.002696374,0.00055548444,0.00041120002,0.00015251814,0.000038028622,0.0006868575],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9954598,0.0019220406,0.00070005324,0.0006826461,0.00022161753,0.0010138231],"domain_scores_gemma":[0.99816304,0.00094156514,0.0002503638,0.00042372633,0.000057392586,0.00016390457],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0017609198,0.00044223212,0.0006210262,0.0002606304,0.000513218,0.000052820407,0.00036638012,0.00069037994,0.00020473961],"category_scores_gemma":[0.00013898606,0.00035512846,0.0002514786,0.00049980567,0.00031810554,0.00024011807,0.000056027737,0.0011321494,0.00015607518],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013293549,0.0025123057,0.90654916,0.00004168148,0.0002728654,0.00077524205,0.003312802,0.0000043515765,0.01694206,0.00020930017,0.0031936853,0.052892976],"study_design_scores_gemma":[0.18878819,0.0065339133,0.19224298,0.000099563076,0.0010494742,0.00096412,0.0008270093,0.0022580863,0.21923876,0.00033340076,0.38450128,0.0031632208],"about_ca_topic_score_codex":0.0013417255,"about_ca_topic_score_gemma":0.006480866,"teacher_disagreement_score":0.7143062,"about_ca_system_score_codex":0.00038684803,"about_ca_system_score_gemma":0.00015796287,"threshold_uncertainty_score":0.9998901},"labels":[],"label_agreement":null},{"id":"W1971817221","doi":"10.1191/0960327102ht235oa","title":"Treatment strategies for early presenting acetaminophen overdose: a survey of medical directors of poison centers in North America and Europe","year":2002,"lang":"en","type":"article","venue":"Human & Experimental Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"NIH Clinical Center; Clinical Trial Center, China Medical University Hospital","keywords":"Acetaminophen; Medicine; Ingestion; acetaminophen overdose; Emergency medicine; Toxicity; Poison control; Anesthesia; Acetylcysteine; Internal medicine","score_opus":0.21904895886778294,"score_gpt":0.440489971731641,"score_spread":0.22144101286385806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971817221","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966932,0.0005345585,0.000012335948,0.00008164053,0.0003175124,0.0008439943,0.00005841575,0.000030245432,0.0014281076],"genre_scores_gemma":[0.9992149,0.00020618676,0.000035391386,0.00011205023,0.0000491088,0.00016313103,0.00004103144,0.000024263758,0.00015392924],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99768096,0.0008264266,0.00054873637,0.00035798003,0.0001855863,0.00040032298],"domain_scores_gemma":[0.99899316,0.00038732865,0.0002752485,0.00014073268,0.000053265452,0.00015028438],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00028342544,0.00023974867,0.00051477243,0.00017126722,0.00014915098,0.000014330636,0.00020837449,0.00030474883,0.0010901024],"category_scores_gemma":[0.000073463925,0.0002353806,0.00007733744,0.00024866534,0.00045882148,0.00013813646,0.00010486054,0.00025159927,0.000009792229],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000990251,0.0053320937,0.46178415,0.00016576098,0.00039673713,0.000060226306,0.020353304,0.000115417315,0.4845781,0.0008121286,0.0001923945,0.025219413],"study_design_scores_gemma":[0.009427473,0.0054098363,0.55645776,0.00003899373,0.00008624778,0.000029970712,0.0018703971,0.0052171396,0.4132539,0.000046837584,0.007596478,0.00056497566],"about_ca_topic_score_codex":0.0016661296,"about_ca_topic_score_gemma":0.0015750531,"teacher_disagreement_score":0.09467359,"about_ca_system_score_codex":0.00011240977,"about_ca_system_score_gemma":0.000044739052,"threshold_uncertainty_score":0.99982303},"labels":[],"label_agreement":null},{"id":"W1972877570","doi":"10.1046/j.1563-258x.2002.01112.x","title":"Risks Associated with Herbal Medicinal Products","year":2002,"lang":"de","type":"article","venue":"Wiener Medizinische Wochenschrift","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Victoria Park","funders":"","keywords":"Medicine; Popularity; Traditional medicine; Drug; Order (exchange); Pharmacology; Environmental health; Business","score_opus":0.22244450173698832,"score_gpt":0.3895397032105401,"score_spread":0.16709520147355178,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972877570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.78197485,0.053640448,0.00027722472,0.033806577,0.029517671,0.0049725096,0.00056682574,0.0013482567,0.09389567],"genre_scores_gemma":[0.97778046,0.0030264833,0.0003401691,0.0054779556,0.0061983783,0.0002926819,0.00020458264,0.00019537643,0.006483907],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99075294,0.0027381417,0.0012871363,0.0016755984,0.0013489779,0.0021971976],"domain_scores_gemma":[0.9952942,0.0009209915,0.00096139644,0.0009310007,0.0006916714,0.0012007029],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.003429343,0.0012423667,0.0012877665,0.00042187382,0.0013307732,0.00013201694,0.0008665367,0.0024644174,0.0060363403],"category_scores_gemma":[0.0019290034,0.00110362,0.00028142935,0.0017394219,0.0014832956,0.0005408821,0.00022210334,0.0060866615,0.0035904376],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006825981,0.023444014,0.05116852,0.0026164637,0.024163416,0.0063605397,0.06915802,0.0020677617,0.2148924,0.0092470655,0.3970014,0.19305442],"study_design_scores_gemma":[0.009312468,0.0018947202,0.003550789,0.0006486136,0.0031450738,0.00017668342,0.00070652267,0.007739305,0.091338344,0.00011892742,0.8793889,0.0019796272],"about_ca_topic_score_codex":0.00013852624,"about_ca_topic_score_gemma":0.0001108676,"teacher_disagreement_score":0.48238754,"about_ca_system_score_codex":0.00021510318,"about_ca_system_score_gemma":0.00041515852,"threshold_uncertainty_score":0.99996936},"labels":[],"label_agreement":null},{"id":"W1974431468","doi":"10.1097/01.mjt.0000140217.48324.e3","title":"Acetaminophen Availability Increases in Canada with No Increase in the Incidence of Reports of Inpatient Hospitalizations with Acetaminophen Overdose and Acute Liver Toxicity","year":2004,"lang":"en","type":"article","venue":"American Journal of Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"CARE Canada","funders":"","keywords":"Medicine; Acetaminophen; Incidence (geometry); acetaminophen overdose; Liver toxicity; Toxicity; Emergency medicine; Drug overdose; Intensive care medicine; Anesthesia; Internal medicine; Poison control; Acetylcysteine","score_opus":0.02719172066244456,"score_gpt":0.3103868603415041,"score_spread":0.2831951396790595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974431468","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988459,0.00023017102,0.00011287035,0.00023068124,0.00006415431,0.00041108494,0.000029343575,0.000003291498,0.00007251249],"genre_scores_gemma":[0.9979073,0.00045823096,0.0006763928,0.00090602273,0.000022585536,0.0000113312635,0.000002483305,0.000012287399,0.0000033870813],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99784726,0.00065154844,0.0007223708,0.00017596922,0.00037347086,0.00022936775],"domain_scores_gemma":[0.9977367,0.00039345393,0.0012093317,0.00023569449,0.0003172444,0.000107597436],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009774781,0.00019132215,0.00048567564,0.00014134104,0.000072417126,0.000008595923,0.00023298054,0.00007256998,0.000019819723],"category_scores_gemma":[0.00009354365,0.00012878218,0.000042678108,0.00064143183,0.00059639255,0.00020234489,0.00004516969,0.00062282424,2.2740413e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021051923,0.001037171,0.97307676,0.000074761774,0.00036168387,0.00044687235,0.0046489555,0.0051748217,0.0061429404,0.000057003166,0.00000716923,0.006866659],"study_design_scores_gemma":[0.0037730136,0.005411835,0.936468,0.0003477515,0.0006844252,0.0013282142,0.003956884,0.00057575956,0.046119615,0.00047224984,0.00041185183,0.0004503637],"about_ca_topic_score_codex":0.25185475,"about_ca_topic_score_gemma":0.18648931,"teacher_disagreement_score":0.06536543,"about_ca_system_score_codex":0.00039221914,"about_ca_system_score_gemma":0.0013728591,"threshold_uncertainty_score":0.82835513},"labels":[],"label_agreement":null},{"id":"W1974452780","doi":"10.1039/c4tx00116h","title":"The Hepatic Reductase Null (HRN<sup>™</sup>) and Reductase Conditional Null (RCN) mouse models as suitable tools to study metabolism, toxicity and carcinogenicity of environmental pollutants","year":2014,"lang":"en","type":"article","venue":"Toxicology Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"Cancer Research UK; King's College London; University of Dundee; Grantová Agentura České Republiky; Univerzita Karlova v Praze","keywords":"Reductase; Null (SQL); Carcinogen; Metabolism; Chemistry; Biochemistry; Enzyme; Toxicology; Biology; Computer science; Data mining","score_opus":0.17657817293031478,"score_gpt":0.4379840723037953,"score_spread":0.2614058993734806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974452780","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99252546,0.0006088801,0.000044784738,0.0015358884,0.00021246856,0.0031229218,0.00114192,0.00005681679,0.00075086864],"genre_scores_gemma":[0.9971182,0.00040960326,0.00013476153,0.00069118635,0.0002463877,0.00048322222,0.0000311619,0.00004974493,0.0008357346],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9903892,0.005868054,0.0007766354,0.00094339874,0.0007417137,0.0012809498],"domain_scores_gemma":[0.9959216,0.0023502551,0.00018849694,0.0006138035,0.00017605005,0.00074975536],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0079930015,0.00042749936,0.00070757244,0.0003886715,0.00204143,0.00010620881,0.000609069,0.00064762845,0.00076853286],"category_scores_gemma":[0.0011977636,0.00037462625,0.0001039726,0.00047169588,0.0016237781,0.00040990498,0.0007475179,0.002181075,0.00011635151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004315504,0.006212771,0.009572104,0.00012914665,0.0009766527,0.00009575674,0.011464535,0.0024460645,0.91555566,0.010375677,0.0013031746,0.03755293],"study_design_scores_gemma":[0.010550005,0.0061899778,0.02735628,0.000028859435,0.0005333452,0.0004995477,0.010478782,0.034867924,0.86875206,0.031515185,0.007939981,0.0012880277],"about_ca_topic_score_codex":0.0002855163,"about_ca_topic_score_gemma":0.00013103025,"teacher_disagreement_score":0.046803594,"about_ca_system_score_codex":0.00021227272,"about_ca_system_score_gemma":0.00022482581,"threshold_uncertainty_score":0.99987054},"labels":[],"label_agreement":null},{"id":"W1974658630","doi":"10.1016/j.annemergmed.2009.05.010","title":"Comparison of the 20-Hour Intravenous and 72-Hour Oral Acetylcysteine Protocols for the Treatment of Acute Acetaminophen Poisoning","year":2009,"lang":"en","type":"article","venue":"Annals of Emergency Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":116,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland; University of Ottawa; Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre; McGill University Health Centre; Alberta Health Services; Queen's University; Centre Hospitalier Universitaire Sainte-Justine; University of Calgary; University of British Columbia","funders":"","keywords":"Medicine; Acetylcysteine; Acetaminophen; acetaminophen overdose; Anesthesia; Emergency medicine; Medical emergency","score_opus":0.43758362570293496,"score_gpt":0.5606509246311039,"score_spread":0.12306729892816892,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974658630","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9720174,0.0025105963,0.0002800042,0.011785206,0.0010474633,0.011638509,0.00009608019,0.000022357237,0.0006023715],"genre_scores_gemma":[0.996064,0.0018545205,0.000056879348,0.00025081437,0.0003051729,0.00087934645,0.000008867285,0.000013311589,0.00056706346],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981344,0.00028480348,0.0008407384,0.00020275009,0.0002110969,0.0003262357],"domain_scores_gemma":[0.9984224,0.000261855,0.000664009,0.00028471244,0.00027755162,0.000089508634],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009706813,0.00022257488,0.0006394705,0.00007407158,0.00025205998,0.0000014492477,0.00027811702,0.00020288132,0.00025806433],"category_scores_gemma":[0.00012536568,0.00012440943,0.00018327881,0.00028154382,0.00022346969,0.000059206173,0.000027359521,0.0002577371,9.766874e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003942113,0.0034068045,0.03569898,0.0006682973,0.002595945,0.0000027492406,0.030182673,0.00094579475,0.66900367,0.0014866977,0.016549759,0.23551655],"study_design_scores_gemma":[0.004890714,0.012868456,0.023329811,0.00025034937,0.0011201045,0.0000077964005,0.0011101804,0.0043566334,0.8571352,0.0016436779,0.09303496,0.00025212765],"about_ca_topic_score_codex":0.000115914874,"about_ca_topic_score_gemma":0.00005686318,"teacher_disagreement_score":0.23526442,"about_ca_system_score_codex":0.000015365162,"about_ca_system_score_gemma":0.000048238162,"threshold_uncertainty_score":0.50732696},"labels":[],"label_agreement":null},{"id":"W1975624043","doi":"10.1016/j.jhep.2012.01.017","title":"Mechanistic biomarkers in acute liver injury: Are we there yet?","year":2012,"lang":"en","type":"letter","venue":"Journal of Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":true,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Liver transplantation; Intensive care medicine; Liver failure; Transplantation; Liver disease; Internal medicine","score_opus":0.14363521272109284,"score_gpt":0.4102834982551052,"score_spread":0.2666482855340123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975624043","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.19325323,0.013596064,0.00034461863,0.75382316,0.03347774,0.0015854028,0.00044030425,0.000121257915,0.0033582118],"genre_scores_gemma":[0.5420584,0.0110188695,0.00045784767,0.43819016,0.0067435117,0.000085753556,0.000065278735,0.00019464192,0.0011855441],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99457484,0.0024901866,0.0012149411,0.0003746719,0.00034976585,0.0009955993],"domain_scores_gemma":[0.99658185,0.00075197977,0.0019001738,0.0002979936,0.00023616277,0.00023181757],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.001635416,0.0005792284,0.0013299386,0.0009965375,0.00018687897,0.00002673978,0.00071239576,0.0043932,0.0020562739],"category_scores_gemma":[0.00014047082,0.00052182993,0.00044205153,0.0003795744,0.00024655895,0.0002523834,0.0001351688,0.009657011,0.0003203114],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012679037,0.0003600185,0.014141312,0.0004558921,0.0025213107,0.010199364,0.00046209627,0.000006846381,0.004164895,0.00011455614,0.9536203,0.012685508],"study_design_scores_gemma":[0.0013659076,0.00040110992,0.0002876652,0.00019991373,0.0010121228,0.003432322,0.00005700183,0.00019048847,0.006108346,0.0022905897,0.9840945,0.0005600384],"about_ca_topic_score_codex":0.000072248826,"about_ca_topic_score_gemma":0.00009758683,"teacher_disagreement_score":0.34880516,"about_ca_system_score_codex":0.0004883376,"about_ca_system_score_gemma":0.0003564324,"threshold_uncertainty_score":0.9997233},"labels":[],"label_agreement":null},{"id":"W1975874890","doi":"10.3109/14659891.2012.661021","title":"A new pattern of drug abuse among injecting drug users in Tashkent city","year":2012,"lang":"en","type":"article","venue":"Journal of Substance Use","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Manchester; McGill University","keywords":"Heroin; Codeine; Euphoriant; Drug; Medicine; Drug misuse; Damages; Substance abuse; Acetaminophen; Diphenhydramine; Dose; Psychiatry; Pharmacology; Morphine; Political science","score_opus":0.1289691500002466,"score_gpt":0.3849615141154005,"score_spread":0.2559923641151539,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975874890","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961232,0.0006761578,0.0005993787,0.00013368398,0.0020261407,0.00026643774,0.000008298022,0.000017380295,0.00014932988],"genre_scores_gemma":[0.9979183,0.00055893144,0.00043054073,0.0003127659,0.0004958443,0.0000046801415,0.0000011235086,0.000022262979,0.00025556044],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9976858,0.00052557985,0.0008687468,0.00014239813,0.0002935765,0.00048389702],"domain_scores_gemma":[0.9979382,0.00044298632,0.00095850014,0.00015392361,0.00015805442,0.0003482937],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022476122,0.00020491733,0.00043254512,0.00031637432,0.00010401028,0.000021969101,0.0002600518,0.00021919941,0.00029924282],"category_scores_gemma":[0.00009712704,0.00019539296,0.0001744622,0.00042239306,0.000083414496,0.0012875103,0.000018849414,0.0016761082,0.000011022786],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043424225,0.00034725023,0.9443047,0.00004551858,0.00009697832,0.000034306853,0.035090085,0.00059113605,0.009741551,0.000012800349,0.0010705582,0.008230883],"study_design_scores_gemma":[0.005479009,0.00012239798,0.62472457,0.00052917714,0.00021266722,0.00012544649,0.0034536605,0.00049222715,0.3499578,0.00021226335,0.014127474,0.0005633319],"about_ca_topic_score_codex":0.00047592347,"about_ca_topic_score_gemma":0.002113894,"teacher_disagreement_score":0.34021625,"about_ca_system_score_codex":0.00023733597,"about_ca_system_score_gemma":0.000086268534,"threshold_uncertainty_score":0.79678935},"labels":[],"label_agreement":null},{"id":"W1976146857","doi":"10.1111/liv.12146","title":"Significant advances towards a reproducible, clinically relevant large animal model of acetaminophen‐induced acute liver failure","year":2013,"lang":"en","type":"letter","venue":"Liver International","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Saint-Luc","funders":"","keywords":"Medicine; Liver transplantation; Intensive care medicine; Acetaminophen; Liver disease; Liver failure; Transplantation; Internal medicine; Pharmacology","score_opus":0.15193734283689272,"score_gpt":0.4129575326626948,"score_spread":0.2610201898258021,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976146857","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.42741165,0.0015604622,0.004485506,0.48436016,0.020826079,0.007143697,0.01021691,0.00090365467,0.043091882],"genre_scores_gemma":[0.69616765,0.004388728,0.0058318437,0.2595905,0.010638687,0.0007444287,0.0015239473,0.00022081917,0.0208934],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9948976,0.00067839073,0.0013515655,0.0013847825,0.00090519886,0.00078247656],"domain_scores_gemma":[0.99670756,0.0004234395,0.0011774986,0.0006844855,0.0008253685,0.00018164021],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0013175149,0.000675769,0.0008570407,0.0003971903,0.0002331609,0.00007089953,0.0013167218,0.0025963124,0.0032826667],"category_scores_gemma":[0.00032409112,0.00065307127,0.0005319714,0.0002128904,0.00025731543,0.00060965464,0.00045154573,0.005929446,0.00066451594],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001705309,0.0012680313,0.00070938887,0.0007716598,0.0037588626,0.00096617924,0.002073045,0.00060073944,0.12077767,0.0016242863,0.8415312,0.024213592],"study_design_scores_gemma":[0.002071371,0.0005792344,0.00033393232,0.00016061717,0.0007066911,0.000089656154,0.000053477444,0.053114105,0.045439146,0.00104068,0.8953872,0.0010239247],"about_ca_topic_score_codex":0.0001271062,"about_ca_topic_score_gemma":0.000022074602,"teacher_disagreement_score":0.268756,"about_ca_system_score_codex":0.00026133528,"about_ca_system_score_gemma":0.0004099062,"threshold_uncertainty_score":0.99959207},"labels":[],"label_agreement":null},{"id":"W1976388831","doi":"10.1371/journal.pone.0011031","title":"Acetaminophen Modulates the Transcriptional Response to Recombinant Interferon-β","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Acetaminophen; Interferon; Gene expression; Gene; Microarray analysis techniques; Transcriptional regulation; Pharmacology; Microarray; Biology; Medicine; Immunology; Genetics","score_opus":0.20364426279957334,"score_gpt":0.37613834688466796,"score_spread":0.17249408408509462,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976388831","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9835143,0.000035882946,0.000071136696,0.01261286,0.001382845,0.0008178531,0.00003354214,0.00012057689,0.0014109667],"genre_scores_gemma":[0.9924714,0.000023802184,0.00049245794,0.002522355,0.0003255859,0.00024804616,0.000008631398,0.000023659299,0.003884039],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982855,0.00060400483,0.00025746922,0.00028277482,0.00020952761,0.00036074859],"domain_scores_gemma":[0.99891895,0.00044199236,0.000060691375,0.0002784719,0.000101069985,0.00019882692],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0015491657,0.00017734604,0.00020158043,0.000103235725,0.00044415175,0.00003509959,0.00035618356,0.00032819345,0.0017597617],"category_scores_gemma":[0.00026185386,0.0001407969,0.00007855215,0.00019874903,0.00012685302,0.00011852443,0.000060718703,0.0016119861,0.00096214254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002225229,0.0011681719,0.000986695,0.000023159551,0.00019025085,0.0000048164447,0.0015310823,0.000028308548,0.98816603,0.0007862167,0.00033883064,0.0045512295],"study_design_scores_gemma":[0.0010928472,0.0004992089,0.016072532,0.000038638642,0.00017878346,0.000015557249,0.00008820468,0.0022488923,0.92191243,0.0021847957,0.055363487,0.00030459135],"about_ca_topic_score_codex":0.000021399677,"about_ca_topic_score_gemma":0.0000692032,"teacher_disagreement_score":0.06625355,"about_ca_system_score_codex":0.000052235457,"about_ca_system_score_gemma":0.00005713756,"threshold_uncertainty_score":0.9998157},"labels":[],"label_agreement":null},{"id":"W1977368374","doi":"10.1016/j.jnutbio.2014.01.010","title":"Aspartate alleviates liver injury and regulates mRNA expressions of TLR4 and NOD signaling-related genes in weaned pigs after lipopolysaccharide challenge","year":2014,"lang":"en","type":"article","venue":"The Journal of Nutritional Biochemistry","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"TLR4; Lipopolysaccharide; Liver injury; Biology; Tumor necrosis factor alpha; Endocrinology; Receptor; Internal medicine; Signal transduction; Immunology; Medicine; Biochemistry","score_opus":0.04165867992607827,"score_gpt":0.33296324659797405,"score_spread":0.2913045666718958,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977368374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98983455,0.008483475,0.000008139743,0.0012861465,0.00011725673,0.00012287384,0.00004481882,0.000008188704,0.000094541996],"genre_scores_gemma":[0.99340564,0.0060300357,0.00012425985,0.00016550899,0.00019575524,0.000010048043,0.0000056238964,0.000011046617,0.000052091393],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986889,0.00034392186,0.00049379485,0.00013410689,0.00016026119,0.0001790611],"domain_scores_gemma":[0.9987533,0.00054421916,0.00035058951,0.000093448216,0.00013489962,0.00012351379],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010856326,0.00015815128,0.00026329872,0.00009759301,0.00012825814,0.000010428986,0.00014485526,0.0003019606,0.00019006278],"category_scores_gemma":[0.00009939421,0.00012367884,0.000069662616,0.0000789317,0.0002675399,0.00010626402,0.00006350095,0.00067857676,0.0000024469132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010488239,0.00029756504,0.0013966163,0.0001818138,0.00010431785,0.000011004663,0.00044132263,0.000034740464,0.9947548,0.00005586815,0.000103668506,0.0015694776],"study_design_scores_gemma":[0.0014371225,0.00017450175,0.002323566,0.00038029786,0.0001137128,0.00018316833,0.000147203,0.00038243592,0.9898505,0.0043060337,0.00055218244,0.00014922528],"about_ca_topic_score_codex":0.000012628918,"about_ca_topic_score_gemma":0.0000034317711,"teacher_disagreement_score":0.004904231,"about_ca_system_score_codex":0.00002430933,"about_ca_system_score_gemma":0.000037057736,"threshold_uncertainty_score":0.5043476},"labels":[],"label_agreement":null},{"id":"W1978891381","doi":"10.1191/0960327105ht564oa","title":"Hepatotoxicity in acute iron poisoning","year":2005,"lang":"en","type":"article","venue":"Human & Experimental Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Children's Hospital of Winnipeg; Children's Hospital Research Institute of Manitoba","funders":"","keywords":"Medicine; Ingestion; Internal medicine; Gastroenterology; Transaminase; Liver injury; Alanine transaminase; Toxicity; Aspartate transaminase; Chemistry; Biochemistry","score_opus":0.13305655560275131,"score_gpt":0.4636575188280546,"score_spread":0.3306009632253033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978891381","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96985584,0.0003337975,0.000028967557,0.0006870262,0.0010118879,0.0009207506,0.000010077431,0.0002616982,0.02688994],"genre_scores_gemma":[0.99309003,0.000047838665,0.00039160065,0.0038204084,0.00060108403,0.00041653574,0.00003666447,0.00005601856,0.0015398436],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965694,0.00078276626,0.00070754107,0.0007156075,0.00021026532,0.0010144118],"domain_scores_gemma":[0.99899143,0.00013846187,0.00021189025,0.00031514693,0.000034097153,0.00030897785],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0007406766,0.00044750448,0.000531799,0.00036193524,0.0006321116,0.00003865586,0.00043680237,0.00087211566,0.007230912],"category_scores_gemma":[0.000027679482,0.0005048524,0.00017158163,0.0003172636,0.00034025978,0.0004034908,0.0002281747,0.0012477266,0.0014666327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031156384,0.0016355496,0.009183509,0.000015108516,0.00007226909,0.00011577733,0.0027004376,0.0003238405,0.9689349,0.004918298,0.0005384392,0.011250332],"study_design_scores_gemma":[0.0034300564,0.0006416959,0.0044823475,0.000017695585,0.000040000563,0.00013336478,0.0004475898,0.0015948954,0.9301186,0.00029989064,0.058194984,0.00059884245],"about_ca_topic_score_codex":0.000099051875,"about_ca_topic_score_gemma":0.00040598505,"teacher_disagreement_score":0.057656545,"about_ca_system_score_codex":0.00083790085,"about_ca_system_score_gemma":0.00006578977,"threshold_uncertainty_score":0.9997403},"labels":[],"label_agreement":null},{"id":"W1983354415","doi":"10.1159/000227280","title":"A Case-Control Study of Single-Pass Albumin Dialysis for Acetaminophen-Induced Acute Liver Failure","year":2009,"lang":"en","type":"article","venue":"Blood Purification","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Internal medicine; Dialysis; Albumin; Acetaminophen; Cirrhosis; Liver disease; Gastroenterology; Liver failure; Extracorporeal; Serum albumin; Model for End-Stage Liver Disease; Hepatic encephalopathy; Liver transplantation; Transplantation; Anesthesia","score_opus":0.11488566436950386,"score_gpt":0.37151232473956597,"score_spread":0.2566266603700621,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983354415","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99363166,0.0000908458,0.0014043674,0.00068566017,0.00035062036,0.0033373344,0.00012381068,0.00011753336,0.00025813814],"genre_scores_gemma":[0.9980295,0.000015596937,0.00057149364,0.00034229347,0.00032068422,0.00049230503,0.00003080627,0.000023695264,0.0001736551],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99768627,0.0006741174,0.0005868263,0.00048660135,0.00019115722,0.0003750579],"domain_scores_gemma":[0.99839216,0.00035077744,0.0004431531,0.00039855362,0.0002700474,0.00014531374],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009301522,0.00027422895,0.00043134237,0.00023453047,0.000392634,0.000033233868,0.0002420893,0.00050566386,0.00009938024],"category_scores_gemma":[0.00013402822,0.00028329916,0.0001778852,0.00041602776,0.000041802126,0.00023296519,0.000015464293,0.00046804253,0.000028634935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005690523,0.005230876,0.0007081905,0.00004534803,0.0009377946,0.000121508056,0.0039536385,0.00011358985,0.9142058,0.0003486023,0.00014210008,0.07362354],"study_design_scores_gemma":[0.0141685335,0.0042686127,0.0102984095,0.000018298399,0.0068381783,0.00045828696,0.001262231,0.004918017,0.9538458,0.0005075297,0.0027333796,0.0006826973],"about_ca_topic_score_codex":0.00005353621,"about_ca_topic_score_gemma":0.00011705772,"teacher_disagreement_score":0.072940834,"about_ca_system_score_codex":0.00006387284,"about_ca_system_score_gemma":0.00005121552,"threshold_uncertainty_score":0.9999619},"labels":[],"label_agreement":null},{"id":"W1984940725","doi":"10.1007/s10067-014-2528-z","title":"Increased incidence of liver enzymes abnormalities in patients treated with isoniazid in combination with disease modifying and/or biologic agents","year":2014,"lang":"en","type":"article","venue":"Clinical Rheumatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute; Université de Montréal","funders":"","keywords":"Medicine; Isoniazid; Internal medicine; Discontinuation; Tuberculosis; Liver function tests; Rheumatology; Latent tuberculosis; Gastroenterology; Mycobacterium tuberculosis; Pathology","score_opus":0.12430817549911154,"score_gpt":0.40959383481796496,"score_spread":0.2852856593188534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984940725","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988403,0.0001013083,0.00008309677,0.00011000581,0.00011129596,0.00058819493,0.000015286963,0.00003686246,0.00011366924],"genre_scores_gemma":[0.99897265,0.00039653823,0.00009672632,0.00037684356,0.000007294727,0.000083937615,0.00003178786,0.000012554959,0.00002163672],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99658304,0.0019045003,0.0007147258,0.0003722871,0.00010586934,0.00031958518],"domain_scores_gemma":[0.9974005,0.0018365143,0.00033625696,0.00015597213,0.00009750087,0.0001732479],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012750808,0.00019882653,0.0005699326,0.00020503982,0.00008711323,0.000007416619,0.00015214461,0.00040717123,0.00007376215],"category_scores_gemma":[0.0010081902,0.00014378119,0.000036199275,0.000261616,0.000555484,0.00015877187,0.00006823039,0.0006416354,0.000010048583],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0062862034,0.001005413,0.98389125,0.00015252219,0.000036822934,0.000025215497,0.0002490993,0.00007810613,0.000011018059,0.0014864984,0.000012731156,0.0067651193],"study_design_scores_gemma":[0.0084002,0.0015552719,0.97621495,0.0001896564,0.00004090023,0.000011083003,0.000049952127,0.012310231,0.0004638758,0.00039907356,0.00016233318,0.00020245892],"about_ca_topic_score_codex":0.00076853065,"about_ca_topic_score_gemma":0.0009173285,"teacher_disagreement_score":0.012232125,"about_ca_system_score_codex":0.000044144836,"about_ca_system_score_gemma":0.000089971385,"threshold_uncertainty_score":0.58632267},"labels":[],"label_agreement":null},{"id":"W1986626457","doi":"10.1007/s11011-005-7927-z","title":"Acute Liver Failure: A Critical Appraisal of Available Animal Models","year":2005,"lang":"en","type":"review","venue":"Metabolic Brain Disease","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":71,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Saint-Luc","funders":"","keywords":"Liver failure; Intensive care medicine; Medicine; Preclinical testing; Animal model; Viral hepatitis; Immunology; Surgery; Internal medicine; Medical physics","score_opus":0.26430532503474913,"score_gpt":0.4852892989798145,"score_spread":0.22098397394506536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986626457","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009437563,0.9917913,0.0002617455,0.000592432,0.0014500824,0.0014569641,0.0019748732,0.00018915972,0.002189068],"genre_scores_gemma":[0.0010010767,0.9935971,0.00049391936,0.0008469801,0.0016625187,0.0007040465,0.00022076016,0.00013222174,0.0013413747],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9942953,0.0022649681,0.0011326998,0.0009407914,0.00043754958,0.00092869054],"domain_scores_gemma":[0.99561363,0.0020335768,0.00044621358,0.0006715337,0.00017413394,0.0010609024],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0012468399,0.0008556541,0.0023206666,0.00042961835,0.00031153156,0.000052694253,0.00075503625,0.0012870143,0.0050480175],"category_scores_gemma":[0.0010012826,0.0008000642,0.0012334624,0.0006685595,0.00050645624,0.00045556403,0.00028162883,0.0022787368,0.0015137922],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042683483,0.0012929009,0.0000042292463,0.01040375,0.0014707464,0.00023254353,0.0002468596,0.00004023026,0.00007685528,0.018534716,0.033255897,0.93401444],"study_design_scores_gemma":[0.0007063292,0.00005284498,0.0000041215553,0.000662399,0.006625563,0.000058893795,0.000007333743,0.002174511,0.00007107288,0.00027896688,0.98863447,0.00072348333],"about_ca_topic_score_codex":0.00002496538,"about_ca_topic_score_gemma":0.000008959509,"teacher_disagreement_score":0.9553786,"about_ca_system_score_codex":0.00008411311,"about_ca_system_score_gemma":0.0009883725,"threshold_uncertainty_score":0.999445},"labels":[],"label_agreement":null},{"id":"W1986636669","doi":"10.1016/s0741-8329(02)00214-8","title":"Synergetic signaling for apoptosis in vitro by ethanol and acetaminophen","year":2002,"lang":"en","type":"article","venue":"Alcohol","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto; Health Sciences Centre","funders":"","keywords":"Acetaminophen; Apoptosis; Pharmacology; In vitro; Chemistry; Mitochondrion; Ethanol; Hepatocyte; Biochemistry; Biology","score_opus":0.15277636982908802,"score_gpt":0.39028339616049307,"score_spread":0.23750702633140505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986636669","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99435437,0.0008689364,0.00024551107,0.0013183246,0.0005003787,0.0008600672,0.00006362859,0.00007383759,0.0017149738],"genre_scores_gemma":[0.99659246,0.0002252889,0.00031496308,0.0014544954,0.00012949857,0.00035622923,0.000018075465,0.000023924093,0.00088504265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99871767,0.00022770288,0.000253878,0.00031146838,0.00008428914,0.00040502386],"domain_scores_gemma":[0.99926823,0.0003881753,0.00007685698,0.00010840858,0.000029936737,0.00012836095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049703603,0.00017619219,0.00022471596,0.00010975804,0.00020961263,0.00002191116,0.00012016662,0.00038512965,0.00033876984],"category_scores_gemma":[0.00008725201,0.00018725399,0.00006175434,0.00016689491,0.0000776774,0.00012700354,0.000035328565,0.0005303291,0.00006678079],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012786545,0.00016721466,0.00090130063,0.00006165288,0.000056646644,0.000002446317,0.00069533923,0.000058472866,0.9557603,0.000059655686,0.0023221003,0.03978702],"study_design_scores_gemma":[0.0018398403,0.00007521776,0.000048190366,0.0000121369085,0.000064211665,0.000004701422,0.00006628244,0.009509994,0.95119673,0.00040255117,0.03654794,0.00023220982],"about_ca_topic_score_codex":0.000028086832,"about_ca_topic_score_gemma":0.000004337315,"teacher_disagreement_score":0.03955481,"about_ca_system_score_codex":0.000055684577,"about_ca_system_score_gemma":0.000008521356,"threshold_uncertainty_score":0.7635996},"labels":[],"label_agreement":null},{"id":"W1987574890","doi":"10.1007/s11011-010-9186-x","title":"Antioxidant and anti-inflammatory effects of mild hypothermia in the attenuation of liver injury due to azoxymethane toxicity in the mouse","year":2010,"lang":"en","type":"article","venue":"Metabolic Brain Disease","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Proinflammatory cytokine; Glutathione; Thioacetamide; Hypothermia; Medicine; Pharmacology; Internal medicine; Endocrinology; Acetaminophen; Toxicity; Inflammation; Chemistry; Biochemistry","score_opus":0.03979503742441407,"score_gpt":0.35089871973016323,"score_spread":0.31110368230574914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987574890","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958663,0.0005200118,0.000031652427,0.0016149746,0.0002581055,0.0015466985,0.00006532144,0.000015493131,0.00008143263],"genre_scores_gemma":[0.99604726,0.00013401551,0.000044536802,0.0034244936,0.00012960022,0.00017687415,0.0000047713656,0.000014452867,0.000023978757],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9969443,0.0019150756,0.0003859531,0.00025248196,0.00023076261,0.00027141257],"domain_scores_gemma":[0.99827296,0.0010395928,0.00016796785,0.00034338524,0.00004745712,0.00012864039],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0028828976,0.00018734173,0.0003263913,0.00024497567,0.0000968388,0.00001328911,0.0003516978,0.00020626625,0.0000483022],"category_scores_gemma":[0.0008537101,0.00013223627,0.00008665662,0.00048223254,0.00021082349,0.00012729333,0.000058869464,0.0007964106,0.000009825334],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042983863,0.0006982328,0.03424227,0.00028836998,0.000036159196,0.00004646959,0.0050282655,0.000055068518,0.93669015,0.0016810154,0.00023122558,0.020572964],"study_design_scores_gemma":[0.0009341419,0.00004033868,0.71232647,0.000021088925,0.000070409886,0.000005117069,0.00008722399,0.00030372402,0.2829111,0.00037457413,0.00279397,0.00013182708],"about_ca_topic_score_codex":0.00018230046,"about_ca_topic_score_gemma":0.00034186526,"teacher_disagreement_score":0.6780842,"about_ca_system_score_codex":0.0000101629,"about_ca_system_score_gemma":0.00007182346,"threshold_uncertainty_score":0.5392438},"labels":[],"label_agreement":null},{"id":"W1991377650","doi":"10.1016/j.toxlet.2014.02.007","title":"Use of a systems model of drug-induced liver injury (DILIsym®) to elucidate the mechanistic differences between acetaminophen and its less-toxic isomer, AMAP, in mice","year":2014,"lang":"en","type":"article","venue":"Toxicology Letters","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McGill University","keywords":"Acetaminophen; Metabolite; Cytochrome P450; Drug metabolism; Metabolism; Drug; Enzyme; Pharmacology; Chemistry; Reactive intermediate; Liver injury; Biochemistry; Biology","score_opus":0.19093323320682717,"score_gpt":0.3586390532600467,"score_spread":0.16770582005321952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991377650","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941718,0.00010287427,0.0010772311,0.0022955392,0.0006855479,0.0013956374,0.00014674859,0.000048620626,0.00007603206],"genre_scores_gemma":[0.9963525,0.000080742306,0.00011174423,0.0029472692,0.00014375958,0.00019869236,0.000008310579,0.00003274715,0.00012423401],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99592876,0.0018957525,0.00079521444,0.0005405574,0.00023188448,0.00060785323],"domain_scores_gemma":[0.99746066,0.001485648,0.0004320285,0.00032035031,0.00009819766,0.00020312553],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015909547,0.00037366667,0.00081852876,0.00040912002,0.00021712414,0.000025935664,0.00051560655,0.00054044113,0.000027134396],"category_scores_gemma":[0.0002705947,0.00031829742,0.00009605833,0.0004038379,0.00026973337,0.00022090701,0.00023895699,0.0010443602,0.0000265512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030016585,0.00016380458,0.006650465,0.00025344396,0.00015763455,0.0000051321763,0.0022951218,0.0030653886,0.98034245,0.0017619028,0.0001958324,0.004808633],"study_design_scores_gemma":[0.0022164518,0.00077869714,0.025063075,0.00019094931,0.00052464864,0.000020460786,0.00039256513,0.16275147,0.80546147,0.00061070477,0.0010972522,0.0008922841],"about_ca_topic_score_codex":0.00036748112,"about_ca_topic_score_gemma":0.00025069495,"teacher_disagreement_score":0.17488103,"about_ca_system_score_codex":0.00009564083,"about_ca_system_score_gemma":0.00006358332,"threshold_uncertainty_score":0.9999269},"labels":[],"label_agreement":null},{"id":"W1992722108","doi":"10.1542/peds.2011-3035","title":"Chronic Acetaminophen Exposure in Pediatric Acute Liver Failure","year":2013,"lang":"en","type":"article","venue":"PEDIATRICS","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Hospital for Sick Children; National Center for Research Resources; University of Arkansas for Medical Sciences; University of Pittsburgh; Johns Hopkins University; University of Cincinnati; University of Washington","keywords":"Medicine; Acetaminophen; Liver transplantation; Bilirubin; Internal medicine; Alanine aminotransferase; Gastroenterology; Liver failure; Transplantation; Anesthesia","score_opus":0.05791655135927054,"score_gpt":0.34919866079567935,"score_spread":0.2912821094364088,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992722108","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894432,0.0029941273,0.00014229302,0.0010979844,0.0016284992,0.0011621985,0.000037001268,0.000197806,0.0032969136],"genre_scores_gemma":[0.9883771,0.005078839,0.0003224841,0.00058559305,0.0036690184,0.0005060435,0.000029071323,0.000041857176,0.0013900026],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9976257,0.00040944948,0.00047617996,0.00046777003,0.00025379905,0.00076710776],"domain_scores_gemma":[0.9988284,0.00029552262,0.00019146978,0.0002750634,0.00012647877,0.00028305437],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00059115735,0.00032424272,0.00031589845,0.00043004635,0.00023861209,0.00005578355,0.0003910628,0.000855586,0.0027619605],"category_scores_gemma":[0.00009856882,0.00033084198,0.00012780887,0.0009945527,0.00006275443,0.00047495528,0.00014230459,0.0017712788,0.0033825317],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012145349,0.0008221868,0.8232308,0.0008051758,0.00015076471,0.00032098632,0.0030437787,0.0013950743,0.009387843,0.0007317465,0.052359838,0.10763033],"study_design_scores_gemma":[0.014488376,0.0016797034,0.60023934,0.00002853163,0.0021979313,0.00026091957,0.00045577003,0.013674252,0.020519247,0.0048003397,0.33760893,0.0040466688],"about_ca_topic_score_codex":0.00014929182,"about_ca_topic_score_gemma":0.00019126332,"teacher_disagreement_score":0.28524908,"about_ca_system_score_codex":0.00030115043,"about_ca_system_score_gemma":0.00021846776,"threshold_uncertainty_score":0.99991435},"labels":[],"label_agreement":null},{"id":"W1993860399","doi":"10.1021/tx700186p","title":"Idiosyncratic Drug Reactions: Past, Present, and Future","year":2007,"lang":"en","type":"review","venue":"Chemical Research in Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":257,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Drug; Mechanism (biology); Computational biology; Drug development; Drug reaction; Pharmacology; Biology","score_opus":0.4860914021122967,"score_gpt":0.5897844246198498,"score_spread":0.10369302250755313,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993860399","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00082318153,0.9785499,0.0000044630174,0.003070054,0.0016729259,0.0029789403,0.000053984706,0.000118777665,0.012727781],"genre_scores_gemma":[0.00044164775,0.98889256,0.0001091119,0.00023725547,0.0074902317,0.0012155038,0.000093751216,0.00009312339,0.0014268227],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9905324,0.0045340336,0.0013229615,0.0012330527,0.0005523172,0.0018252223],"domain_scores_gemma":[0.99201494,0.006177658,0.00030516466,0.0005619356,0.00019473398,0.0007455364],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.007784112,0.0006572022,0.001810282,0.0013630111,0.0004155169,0.00006553166,0.0007963958,0.0038299998,0.00070826005],"category_scores_gemma":[0.00042362558,0.0006047844,0.000311973,0.001797759,0.0011253805,0.00017259028,0.0006067871,0.012012492,0.0004449038],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012593847,0.00048182823,0.000012885477,0.009440324,0.0001565717,0.00027332734,0.00014682894,5.448437e-7,0.0007358294,0.0010700319,0.009512928,0.97804296],"study_design_scores_gemma":[0.000672907,0.000101170954,0.0000035905844,0.0011785253,0.00013408203,0.00031951597,0.00009440486,0.000045005352,0.0014468429,0.0019115277,0.9936006,0.00049183844],"about_ca_topic_score_codex":0.000050691975,"about_ca_topic_score_gemma":0.000026796508,"teacher_disagreement_score":0.98408765,"about_ca_system_score_codex":0.00096059556,"about_ca_system_score_gemma":0.00059295923,"threshold_uncertainty_score":0.99964035},"labels":[],"label_agreement":null},{"id":"W1996257927","doi":"10.1503/cmaj.121732","title":"Isoniazid toxicity in a 5-year-old boy","year":2013,"lang":"en","type":"article","venue":"Canadian Medical Association Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; McMaster University; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Isoniazid; Medicine; Tuberculosis; Medical history; Pediatrics; Pulmonary tuberculosis; Past medical history; Surgery; Pathology","score_opus":0.04378947058504825,"score_gpt":0.3525741662017276,"score_spread":0.30878469561667937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996257927","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93009603,0.0000685809,0.000036061323,0.052253462,0.0023658872,0.00034171445,0.000019757146,0.000034667628,0.014783855],"genre_scores_gemma":[0.96820414,0.00013399817,0.00005385515,0.028394565,0.0013661127,0.000043566855,0.0000046697755,0.000015234536,0.0017838856],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.997148,0.00079048093,0.00049517007,0.0001858716,0.0006171102,0.0007634177],"domain_scores_gemma":[0.9974814,0.00022650287,0.00019427117,0.000082811865,0.00023675752,0.0017782376],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0030492246,0.00015043124,0.0002332989,0.00029029342,0.00038032318,0.000092833,0.0002764479,0.0011633212,0.023089495],"category_scores_gemma":[0.0015437085,0.00015233226,0.00009606842,0.00036972624,0.0000385088,0.00028991658,0.000021230124,0.0035246634,0.002372773],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037453825,0.0002601539,0.5273071,0.000023804732,0.00019263581,0.00044087088,0.0014909484,0.00007704915,0.0016879803,0.0013262967,0.29345885,0.17369688],"study_design_scores_gemma":[0.0029436392,0.00010447817,0.13715829,0.000059120754,0.000028355385,0.00029653194,0.00077506405,0.0034086292,0.001465773,0.003110075,0.8502113,0.00043870613],"about_ca_topic_score_codex":0.010360285,"about_ca_topic_score_gemma":0.055980857,"teacher_disagreement_score":0.5567525,"about_ca_system_score_codex":0.0015549423,"about_ca_system_score_gemma":0.0013084775,"threshold_uncertainty_score":0.99877423},"labels":[],"label_agreement":null},{"id":"W1998843764","doi":"10.3109/15563650.2014.954125","title":"Impact of reducing the threshold for acetylcysteine treatment in acute paracetamol poisoning: The recent United Kingdom experience","year":2014,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute for Health and Care Research","keywords":"Acetylcysteine; Medicine; Acetaminophen; Antidote; acetaminophen overdose; Nomogram; Anesthesia; Drug overdose; Retrospective cohort study; Emergency medicine; Cohort; Medication error; Poison control; Toxicity; Internal medicine; Patient safety","score_opus":0.39441577960611435,"score_gpt":0.5598804845395484,"score_spread":0.16546470493343407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998843764","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98910666,0.00008773617,0.00029225257,0.005811854,0.0017924547,0.0020313843,0.000030662028,0.00004911111,0.00079791475],"genre_scores_gemma":[0.996031,0.00044362372,0.00012050981,0.0019313075,0.00046865063,0.0007235684,0.000021879336,0.000025920883,0.00023353733],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.99546677,0.0021845594,0.0010919146,0.00049686735,0.00012127314,0.00063861004],"domain_scores_gemma":[0.9930473,0.0055838088,0.0005145673,0.00054693356,0.00013980275,0.00016757981],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0035377853,0.00030127488,0.0006622189,0.00013066705,0.00041989182,0.000019195117,0.00056096644,0.0007370308,0.00021846942],"category_scores_gemma":[0.0014246026,0.00016946458,0.00041517863,0.00055786746,0.0007571623,0.00007850557,0.00011663746,0.0011201291,0.000020448158],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016795408,0.0096673155,0.3944737,0.000121129866,0.0038422896,0.000054449,0.015344729,0.04652986,0.1424269,0.027445592,0.005310707,0.33798793],"study_design_scores_gemma":[0.021968795,0.017772496,0.08850064,0.00010354366,0.0010096239,0.00015489348,0.00069975154,0.16400965,0.08641998,0.0039930637,0.6143118,0.0010557442],"about_ca_topic_score_codex":0.00020369046,"about_ca_topic_score_gemma":0.00013707909,"teacher_disagreement_score":0.6090011,"about_ca_system_score_codex":0.00020632186,"about_ca_system_score_gemma":0.00019116825,"threshold_uncertainty_score":0.6910565},"labels":[],"label_agreement":null},{"id":"W1999383618","doi":"10.1053/j.gastro.2006.11.025","title":"Mild Hypothermia Attenuates Liver Injury and Improves Survival in Mice With Acetaminophen Toxicity","year":2006,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":74,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Saint-Luc","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Acetaminophen; Hypothermia; Liver injury; Medicine; Hepatocyte; Pharmacology; Toxicity; Glutathione; Glycogen; Centrilobular necrosis; Endocrinology; Internal medicine; Anesthesia; Chemistry; Biochemistry; Enzyme","score_opus":0.046498417725547955,"score_gpt":0.3225023696494924,"score_spread":0.27600395192394445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999383618","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99701726,0.00011936416,0.00012760573,0.0008515222,0.00043848465,0.00046953215,0.00004388521,0.00007392086,0.00085843744],"genre_scores_gemma":[0.99741244,0.00007131956,0.0002912541,0.0015570695,0.00023466804,0.000080612066,0.000015905105,0.000026642078,0.00031005926],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9978749,0.00063015195,0.00031790437,0.00044433188,0.0000995084,0.00063315924],"domain_scores_gemma":[0.9994279,0.00013981138,0.00013896037,0.00013930179,0.00004338362,0.0001106508],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005052371,0.00027291256,0.00035418003,0.00016789314,0.00015311888,0.0000186465,0.00017096833,0.00035656063,0.00011434651],"category_scores_gemma":[0.000017260158,0.00025146737,0.00004603906,0.00013097977,0.00033505206,0.00015452839,0.0000909688,0.0008261734,0.00003852113],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00366069,0.00048116755,0.6229277,0.00006488262,0.00010311893,0.00007906223,0.00032262685,0.00012794088,0.36430442,0.00019274653,0.0004476083,0.0072879805],"study_design_scores_gemma":[0.005809875,0.0019001616,0.8909917,0.00002929889,0.0001272556,0.0001986164,0.00014453304,0.0018254357,0.09210648,0.0007409113,0.0057019666,0.00042376984],"about_ca_topic_score_codex":0.0006063597,"about_ca_topic_score_gemma":0.003745534,"teacher_disagreement_score":0.27219793,"about_ca_system_score_codex":0.000073318566,"about_ca_system_score_gemma":0.000024687644,"threshold_uncertainty_score":0.99999374},"labels":[],"label_agreement":null},{"id":"W2000066924","doi":"10.1001/jama.296.1.87","title":"Aminotransferase Elevations in Healthy Adults Receiving 4 Grams of Acetaminophen Daily","year":2006,"lang":"en","type":"article","venue":"JAMA","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":638,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Purdue Pharma (Canada)","funders":"National Center for Research Resources","keywords":"Acetaminophen; Medicine; Placebo; Incidence (geometry); Confidence interval; Internal medicine; Alanine aminotransferase; Randomized controlled trial; Clinical trial; Anesthesia","score_opus":0.07086715841328335,"score_gpt":0.3783518780706333,"score_spread":0.30748471965734997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000066924","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904445,0.00012309337,0.00031529707,0.001680628,0.0005815189,0.0005802123,0.00006204325,0.00007287186,0.006139836],"genre_scores_gemma":[0.9981059,0.00009503081,0.0002523202,0.0008454533,0.00028517793,0.00009493953,0.000058379857,0.000017823348,0.00024499756],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9982759,0.00041429605,0.0005193934,0.0002687478,0.00014529051,0.00037641526],"domain_scores_gemma":[0.9992127,0.00029902253,0.0001312383,0.00016988328,0.000096938034,0.00009020898],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00071878795,0.00016209077,0.0002484138,0.00019385522,0.00016605362,0.00001469724,0.00016586832,0.0004346034,0.00025456224],"category_scores_gemma":[0.0001010098,0.00017616534,0.00007651052,0.0004656887,0.00009054543,0.0002184533,0.000023530178,0.0008787738,0.000058881134],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0070183785,0.0032567964,0.2068565,0.00084306055,0.0001201265,0.000081208746,0.0058447444,0.0038414786,0.30482036,0.010870145,0.0024440233,0.45400319],"study_design_scores_gemma":[0.016956806,0.0010113864,0.52347004,0.00023050749,0.00010132234,0.000034649016,0.00053850363,0.009513633,0.39777598,0.0048533,0.044721536,0.00079232524],"about_ca_topic_score_codex":0.0016441499,"about_ca_topic_score_gemma":0.0018033241,"teacher_disagreement_score":0.45321086,"about_ca_system_score_codex":0.00011268605,"about_ca_system_score_gemma":0.0000800612,"threshold_uncertainty_score":0.7183814},"labels":[],"label_agreement":null},{"id":"W2000347666","doi":"10.2165/00128071-200506060-00003","title":"Monitoring Liver Function during Methotrexate Therapy for Psoriasis","year":2005,"lang":"en","type":"review","venue":"American Journal of Clinical Dermatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Methotrexate; Medicine; Psoriasis; Liver biopsy; Biopsy; Pharmacotherapy; Liver function; Liver function tests; Internal medicine; Liver disease; Dermatology","score_opus":0.4229021072902276,"score_gpt":0.5805141046800265,"score_spread":0.15761199738979892,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000347666","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010678381,0.97729087,0.0008448518,0.00031192647,0.009676619,0.0009560454,0.00003433515,0.000056503213,0.00015049076],"genre_scores_gemma":[0.00737018,0.9845273,0.00164572,0.00041515974,0.0057377513,0.000117862175,0.0000066349817,0.000087115375,0.00009231393],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9903164,0.0048979316,0.003458409,0.00047503403,0.0002249573,0.0006272891],"domain_scores_gemma":[0.9884573,0.0057427087,0.004716838,0.00028397134,0.00036210284,0.00043704011],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0030299602,0.00056173967,0.0042317873,0.00046502007,0.0003015514,0.000027349783,0.00058799767,0.0012984424,0.00015611618],"category_scores_gemma":[0.0008149966,0.00045930487,0.0021965695,0.00043229744,0.000502405,0.00021308943,0.00006876153,0.003923311,0.000095321644],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00095760974,0.00031415583,0.00041642674,0.00090826204,0.00173911,0.00010144801,0.0000662421,0.000010428462,0.000009218204,0.00003398158,0.00020238945,0.99524075],"study_design_scores_gemma":[0.0020933247,0.0008938217,0.0002025104,0.0008584536,0.0019413966,0.002072603,0.000073950796,0.000025845744,0.00015382301,0.00007654753,0.991199,0.00040873175],"about_ca_topic_score_codex":0.0000089884725,"about_ca_topic_score_gemma":0.0000020961518,"teacher_disagreement_score":0.994832,"about_ca_system_score_codex":0.00012607871,"about_ca_system_score_gemma":0.00048088797,"threshold_uncertainty_score":0.9999981},"labels":[],"label_agreement":null},{"id":"W2001681662","doi":"10.3109/13880209.2014.950675","title":"Phytoextract of Indian mustard seeds acts by suppressing the generation of ROS against acetaminophen-induced hepatotoxicity in HepG2 cells","year":2014,"lang":"en","type":"article","venue":"Pharmaceutical Biology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Indian Institute of Technology Bombay; McGill University","keywords":"Chemistry; DPPH; Reactive oxygen species; ABTS; Pharmacology; Antioxidant; Hepatoprotection; Context (archaeology); Toxicity; Pulegone; Quercetin; Traditional medicine; Catechin; Biochemistry; Glutathione; Food science; Biology; Polyphenol; Medicine; Essential oil","score_opus":0.17070521273082798,"score_gpt":0.42449351241000566,"score_spread":0.2537882996791777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001681662","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935297,0.00024396727,0.00034750596,0.00091957144,0.0014409231,0.00097264233,0.00012907371,0.000055403223,0.0023612163],"genre_scores_gemma":[0.9970658,0.00026510327,0.00009870317,0.001969978,0.00036307907,0.00009094058,0.00008426777,0.000033247856,0.000028924318],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99470687,0.0027924678,0.00096455216,0.00054199214,0.0002112817,0.0007828263],"domain_scores_gemma":[0.9977107,0.0010665136,0.00046620265,0.00035596636,0.00013621864,0.00026439162],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0025038326,0.0003912644,0.00067885185,0.0002298834,0.0002667666,0.000017812035,0.00051903725,0.0009203738,0.0002736139],"category_scores_gemma":[0.00031245698,0.0003225862,0.0001858305,0.0004993931,0.0006132794,0.00018611211,0.00012546808,0.0018233398,0.00004191137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028693068,0.00056925614,0.007854688,0.00013275073,0.00009979452,0.0000044320805,0.00070284284,0.00037859927,0.95748824,0.00038196816,0.00027149476,0.03182899],"study_design_scores_gemma":[0.0019033751,0.00023122452,0.0008585945,0.000025537196,0.00007349039,0.000007855816,0.00006320651,0.022269275,0.9546658,0.00022925259,0.019366996,0.00030539304],"about_ca_topic_score_codex":0.00008459452,"about_ca_topic_score_gemma":0.000063739295,"teacher_disagreement_score":0.031523596,"about_ca_system_score_codex":0.00011808701,"about_ca_system_score_gemma":0.00010589575,"threshold_uncertainty_score":0.99992263},"labels":[],"label_agreement":null},{"id":"W2001787888","doi":"10.1097/00042752-200001000-00018","title":"Anabolic Steroid-Induced Hepatoxicity","year":2000,"lang":"en","type":"article","venue":"Clinical Journal of Sport Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Medicine; Anabolic steroid; Anabolism; Anabolic Agents; Internal medicine","score_opus":0.29294879606651764,"score_gpt":0.5291445288976167,"score_spread":0.23619573283109901,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001787888","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.981075,0.00047693527,0.000040604227,0.0041988594,0.004020993,0.00027631046,0.0000038840617,0.000047421523,0.0098600155],"genre_scores_gemma":[0.98228747,0.0025716333,0.000111257024,0.009412212,0.0047085723,0.0000042436445,0.0000047637263,0.000026027186,0.0008738441],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99639416,0.0002516814,0.0021712945,0.00028780208,0.0004482849,0.00044676987],"domain_scores_gemma":[0.99748814,0.00033079158,0.0008356471,0.00026659472,0.00028773697,0.0007910839],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.005794506,0.00027001443,0.0010093657,0.00020120127,0.0001988085,0.000009361583,0.00046875217,0.00068411045,0.008026801],"category_scores_gemma":[0.00025826928,0.00020581226,0.00033388674,0.00038395563,0.00040847625,0.00022906394,0.00003092811,0.003030254,0.000280937],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026763792,0.0013254193,0.2400168,0.0000563401,0.0004571712,0.0010899832,0.00066461915,0.0000649324,0.009331644,0.0003236637,0.010599791,0.73339325],"study_design_scores_gemma":[0.009165262,0.0031787355,0.15720977,0.00024821857,0.00052461366,0.0009901703,0.00017416413,0.00037849657,0.009026434,0.0014981506,0.817185,0.0004209866],"about_ca_topic_score_codex":0.000042528212,"about_ca_topic_score_gemma":0.00001385945,"teacher_disagreement_score":0.8065852,"about_ca_system_score_codex":0.000074522024,"about_ca_system_score_gemma":0.0001897726,"threshold_uncertainty_score":0.9992698},"labels":[],"label_agreement":null},{"id":"W2003032127","doi":"10.1177/1098612x11432238","title":"Successful treatment of hepatic failure secondary to diazepam administration in a cat","year":2012,"lang":"en","type":"article","venue":"Journal of Feline Medicine and Surgery","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; Health Sciences Centre","funders":"","keywords":"Diazepam; Medicine; CATS; Fulminant hepatic failure; Oral administration; Liver failure; Anesthesia; Administration (probate law); Intensive care medicine; Pharmacology; Internal medicine","score_opus":0.14661180702382604,"score_gpt":0.43476802943954734,"score_spread":0.2881562224157213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003032127","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98982173,0.001758362,0.00007766374,0.006863296,0.001049527,0.00019405414,0.0000069226276,0.000005402107,0.00022303379],"genre_scores_gemma":[0.9963144,0.0014528799,0.00010098556,0.00083075743,0.0012150626,0.000010410233,0.000007077628,0.000008433104,0.00005996857],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984053,0.00033239461,0.00078366516,0.000088474335,0.00015738374,0.00023279758],"domain_scores_gemma":[0.998349,0.0008161854,0.0003591954,0.000072312076,0.000115617106,0.00028769945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017513486,0.00014218387,0.00055180956,0.00043899342,0.000053014686,0.000003869284,0.000048662794,0.0001662141,0.00027078015],"category_scores_gemma":[0.00029516945,0.000104071536,0.00009123445,0.0002576205,0.00006634885,0.00019553663,0.000009332721,0.000275897,0.0000038699427],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014391784,0.0013496736,0.77675,0.0002666858,0.00020477151,0.00014690947,0.007466183,0.000050054467,0.047083095,0.00003657946,0.0065991767,0.15860765],"study_design_scores_gemma":[0.009292328,0.006833375,0.2663638,0.0010332996,0.00094442477,0.0019204558,0.006081502,0.00076368474,0.2449802,0.0004673626,0.460503,0.00081653806],"about_ca_topic_score_codex":0.000097453776,"about_ca_topic_score_gemma":0.00017996045,"teacher_disagreement_score":0.5103862,"about_ca_system_score_codex":0.000079759586,"about_ca_system_score_gemma":0.00018004938,"threshold_uncertainty_score":0.4243914},"labels":[],"label_agreement":null},{"id":"W2005279936","doi":"10.1182/blood-2011-08-335612","title":"Warfarin and acetaminophen interaction: a summary of the evidence and biologic plausibility","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Duke Clinical Research Institute; National Heart, Lung, and Blood Institute","keywords":"Warfarin; Acetaminophen; Medicine; Aspirin; Atrial fibrillation; Anesthesia; Diabetes mellitus; Internal medicine","score_opus":0.3323914774285354,"score_gpt":0.4118783597788498,"score_spread":0.07948688235031437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005279936","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956217,0.0008549951,0.0000074314707,0.000157847,0.00039356752,0.00034550956,0.000010761386,0.00002727682,0.0025809025],"genre_scores_gemma":[0.99898964,0.00043567547,0.00010086337,0.0002541841,0.00004925239,0.000026342987,6.3082143e-7,0.00000451549,0.0001388976],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989804,0.00042166677,0.00018794801,0.00021546577,0.000053028507,0.00014149131],"domain_scores_gemma":[0.9993631,0.00026213287,0.00011442736,0.00016364022,0.000035866437,0.000060802555],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000624683,0.00010521239,0.0001412617,0.000030449022,0.00016887322,0.0000058650285,0.00012564725,0.00021105532,0.00015275736],"category_scores_gemma":[0.00016334793,0.00007437259,0.000037537764,0.00009857423,0.0002657397,0.0001332259,0.00016161098,0.0004668322,0.0000058631217],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040569654,0.0008482983,0.7947891,0.00021754952,0.0001804173,0.00000839236,0.0036924302,0.0000017157492,0.18079612,0.00071827037,0.000079836864,0.018262185],"study_design_scores_gemma":[0.0011622591,0.0002874134,0.42229068,0.00009018949,0.00024286612,0.00010688816,0.00024234311,0.00011952708,0.5703849,0.0025812984,0.002315578,0.00017601663],"about_ca_topic_score_codex":0.0001464434,"about_ca_topic_score_gemma":0.000075446966,"teacher_disagreement_score":0.38958883,"about_ca_system_score_codex":0.0000113417145,"about_ca_system_score_gemma":0.00002594083,"threshold_uncertainty_score":0.30328262},"labels":[],"label_agreement":null},{"id":"W2006719058","doi":"10.1002/1099-1263(200011/12)20:6<455::aid-jat714>3.0.co;2-a","title":"Biochemical effects of chloral hydrate on male rats following 7-day drinking water exposure","year":2000,"lang":"en","type":"article","venue":"Journal of Applied Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Chloral hydrate; Endocrinology; Internal medicine; Chemistry; Glutathione; Triglyceride; Toxicity; Aldehyde dehydrogenase; Biochemistry; Cholesterol; Enzyme; Biology; Pharmacology; Medicine","score_opus":0.036073893907184996,"score_gpt":0.3405917123051174,"score_spread":0.3045178183979324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006719058","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98570657,0.00012875092,0.000059905095,0.0004652211,0.0020760945,0.0004728822,0.00000313431,0.000032047963,0.0110554015],"genre_scores_gemma":[0.9966908,0.000089623725,0.00020038534,0.0018329597,0.00067195576,0.0000342969,0.0000056081117,0.000034520446,0.00043984444],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975289,0.00046707265,0.0008405217,0.00028539257,0.00027658552,0.0006015295],"domain_scores_gemma":[0.998583,0.00055890466,0.00036381272,0.00018580152,0.000069046946,0.00023940012],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015047697,0.00030776512,0.0007013072,0.00026568552,0.00022103311,0.000017284552,0.0003600587,0.00085490884,0.0015327192],"category_scores_gemma":[0.000053330816,0.00024407788,0.0003376859,0.00019765468,0.00016117045,0.00012367526,0.000053404347,0.0017107248,0.00018778523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001846359,0.00063499785,0.00042092678,0.000078583726,0.00035387222,0.00028069064,0.0011401247,0.0012344586,0.96912533,0.00035798107,0.0009365164,0.023590177],"study_design_scores_gemma":[0.0028462955,0.0010483129,0.00037066173,0.000053741434,0.00020595288,0.00012882361,0.00004046797,0.000126319,0.976356,0.0018516536,0.016725054,0.00024669422],"about_ca_topic_score_codex":0.0000018512774,"about_ca_topic_score_gemma":0.0000024856236,"teacher_disagreement_score":0.023343483,"about_ca_system_score_codex":0.00012676728,"about_ca_system_score_gemma":0.00007691507,"threshold_uncertainty_score":0.99938},"labels":[],"label_agreement":null},{"id":"W2008337379","doi":"10.1016/j.jep.2006.11.003","title":"Hepatoprotective and antioxidant effects of Cuscuta chinensis against acetaminophen-induced hepatotoxicity in rats","year":2006,"lang":"en","type":"article","venue":"Journal of Ethnopharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":161,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Antioxidant; Acetaminophen; Traditional medicine; Cuscuta; Pharmacognosy; Phytotherapy; Chemistry; Pharmacology; Biology; Medicine; Botany; Biochemistry; Biological activity; In vitro","score_opus":0.045957355486082416,"score_gpt":0.37667275293004315,"score_spread":0.3307153974439607,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008337379","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932803,0.0013625583,0.00012427465,0.00053664966,0.0029214425,0.0010528392,0.000015249276,0.000034538516,0.0006721487],"genre_scores_gemma":[0.9977137,0.00071299507,0.000265258,0.0006532228,0.00051086966,0.000047472935,0.000002057681,0.000038787857,0.000055666354],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9953649,0.0017889678,0.0014956316,0.00039470894,0.00032765252,0.00062814594],"domain_scores_gemma":[0.99672955,0.0011354168,0.001348579,0.00017332322,0.00036557144,0.0002475648],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0021243936,0.00042575054,0.001144661,0.0008165269,0.00020261771,0.000016647398,0.00034637083,0.0008542713,0.00008588819],"category_scores_gemma":[0.00037901275,0.00039765827,0.00025625172,0.0007012772,0.0003370763,0.00034680398,0.00013962346,0.0026394485,0.000011590366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010025058,0.0010396325,0.037390377,0.0002922749,0.00023879325,0.00049679773,0.000789634,0.0005841139,0.9409463,0.00013058985,0.00022247073,0.016866509],"study_design_scores_gemma":[0.005332397,0.0008171019,0.052771673,0.00010636735,0.00022494269,0.00008327009,0.000092919574,0.0018872115,0.93600005,0.0013614992,0.0009802335,0.00034235936],"about_ca_topic_score_codex":0.0002599745,"about_ca_topic_score_gemma":0.00013948513,"teacher_disagreement_score":0.01652415,"about_ca_system_score_codex":0.00024315529,"about_ca_system_score_gemma":0.00022035316,"threshold_uncertainty_score":0.99984753},"labels":[],"label_agreement":null},{"id":"W2008522807","doi":"10.1111/j.1939-165x.2007.tb00177.x","title":"Effect of serum storage, anti‐inflammatory oral doses of prednisone, and spontaneous hyperadrenocorticism on serum glutamate dehydrogenase activity in dogs","year":2007,"lang":"en","type":"article","venue":"Veterinary Clinical Pathology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Shared Health; University of Saskatchewan","funders":"","keywords":"Prednisone; Glutamate dehydrogenase; Lactate dehydrogenase; Medicine; Internal medicine; Gastroenterology; Endocrinology; Pharmacology; Biology; Enzyme; Glutamate receptor; Biochemistry","score_opus":0.12024948243644602,"score_gpt":0.47091388331902156,"score_spread":0.35066440088257556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008522807","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99721223,0.00012843635,0.00002398852,0.00007167192,0.0012190703,0.00085716485,0.00010657013,0.00006395659,0.00031690436],"genre_scores_gemma":[0.9991791,0.0002536144,0.0000759138,0.00029116884,0.00010694995,0.000025181233,0.000004798696,0.000030771433,0.000032468994],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9942039,0.0034915449,0.0010467292,0.00054711336,0.00015298543,0.00055769016],"domain_scores_gemma":[0.9959445,0.0029473898,0.0004671292,0.00032826717,0.00004695789,0.00026574376],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00516478,0.00033042752,0.0009616069,0.00027243703,0.00011155746,0.0000049666914,0.000212109,0.0010164789,0.000091315465],"category_scores_gemma":[0.00055447343,0.00030943454,0.00018579749,0.00022291014,0.0006379075,0.00011239401,0.00017557433,0.0013804291,0.00002062545],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018557182,0.0013618817,0.25751656,0.00062302337,0.0001251426,0.014874508,0.000458574,0.00022323651,0.5488034,0.0000686376,0.000007093558,0.15738077],"study_design_scores_gemma":[0.007879244,0.024726527,0.56133,0.0001212921,0.00016999352,0.004230997,0.000045017394,0.0010111051,0.39874986,0.000185923,0.0010248355,0.0005251732],"about_ca_topic_score_codex":0.000024051922,"about_ca_topic_score_gemma":0.000051949406,"teacher_disagreement_score":0.3038135,"about_ca_system_score_codex":0.00005695856,"about_ca_system_score_gemma":0.000059434256,"threshold_uncertainty_score":0.99993575},"labels":[],"label_agreement":null},{"id":"W2010766933","doi":"10.1212/wnl.0b013e3182a2cc4a","title":"Glatiramer acetate–induced acute hepatotoxicity in an adolescent with MS","year":2013,"lang":"en","type":"article","venue":"Neurology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Sickkids Research Institute; Hospital for Sick Children; Multiple Sclerosis Society of Canada; Rare Disease Foundation; Canadian Institutes of Health Research; Teva Pharmaceutical Industries; Dairy Farmers of Ontario; National Institutes of Health; American Liver Foundation; EMD Serono; National Multiple Sclerosis Society","keywords":"Glatiramer acetate; Multiple sclerosis; Medicine; Internal medicine; Pharmacology; Immunology","score_opus":0.10727228276668428,"score_gpt":0.3914634713478933,"score_spread":0.284191188581209,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010766933","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992372,0.000018584951,0.00007787193,0.0027058208,0.0008614923,0.001385166,0.000012355246,0.0001919703,0.0023747697],"genre_scores_gemma":[0.9857421,0.000038955197,0.00008798602,0.013427268,0.00020893337,0.00035715144,0.000018674693,0.000047068042,0.00007187651],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99668884,0.0012564159,0.00041119725,0.0006551209,0.00017229131,0.00081614155],"domain_scores_gemma":[0.99888533,0.00014572345,0.00017025003,0.00036121195,0.00010676618,0.0003307369],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00040422042,0.0003552838,0.00042667324,0.0002385044,0.0002231062,0.00003807626,0.00034941794,0.00077432155,0.0012603706],"category_scores_gemma":[0.00002713176,0.0003169524,0.00006988492,0.00038723744,0.00020285074,0.00043470418,0.00008949074,0.0023889854,0.0006956212],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030410124,0.0015837804,0.44290408,0.000046541554,0.00017013156,0.0003877029,0.0010700738,0.00066572754,0.51017696,0.00051777164,0.00041495296,0.039021254],"study_design_scores_gemma":[0.006929258,0.005752783,0.78743565,0.000019626967,0.00016672297,0.00044071992,0.00003448082,0.025069496,0.15402076,0.0015984847,0.017444395,0.0010876106],"about_ca_topic_score_codex":0.0008849547,"about_ca_topic_score_gemma":0.001451572,"teacher_disagreement_score":0.3561562,"about_ca_system_score_codex":0.000058323098,"about_ca_system_score_gemma":0.000079423924,"threshold_uncertainty_score":0.99992824},"labels":[],"label_agreement":null},{"id":"W2010948092","doi":"10.1021/tx500284g","title":"Absolute Quantitation of NAPQI-Modified Rat Serum Albumin by LC–MS/MS: Monitoring Acetaminophen Covalent Binding<i>in Vivo</i>","year":2014,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Chemistry; In vivo; Acetaminophen; Chromatography; Albumin; Serum albumin; Covalent bond; Biochemistry; Organic chemistry; Biology","score_opus":0.2763701473017475,"score_gpt":0.49789839968011984,"score_spread":0.22152825237837231,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010948092","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99101186,0.00024238537,0.000070163675,0.0015173851,0.0011652806,0.0012266369,0.000051806583,0.00005454865,0.004659924],"genre_scores_gemma":[0.9978274,0.0003533967,0.00015944005,0.00017217323,0.00028706688,0.0005026902,0.00002427007,0.00004029403,0.0006332419],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99421895,0.0022894426,0.0008839571,0.0007255399,0.00053920486,0.0013429079],"domain_scores_gemma":[0.9960338,0.0028625063,0.00020799847,0.00035269457,0.00020019026,0.00034284726],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0059477394,0.0003094026,0.00062869745,0.00065879733,0.00019058195,0.000027249585,0.0006436067,0.0012770948,0.00037008495],"category_scores_gemma":[0.0014489212,0.00033443663,0.00011533307,0.0010540624,0.0006659859,0.00020690523,0.00028583748,0.00296424,0.00012658749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000625157,0.000753238,0.008477479,0.00025334847,0.00003991702,0.000022588361,0.00053989206,0.00021512876,0.97890246,0.0010498485,0.001820134,0.0073008193],"study_design_scores_gemma":[0.0027716984,0.00036126148,0.0010949807,0.00010028934,0.000015909238,0.000008574593,0.00014890093,0.00400885,0.96959025,0.0014781113,0.020132493,0.00028865697],"about_ca_topic_score_codex":0.00019540456,"about_ca_topic_score_gemma":0.000108774504,"teacher_disagreement_score":0.01831236,"about_ca_system_score_codex":0.0006712168,"about_ca_system_score_gemma":0.00018276056,"threshold_uncertainty_score":0.9999108},"labels":[],"label_agreement":null},{"id":"W2012393743","doi":"10.1517/14740338.5.2.231","title":"Adverse reactions to first-line antituberculosis drugs","year":2006,"lang":"en","type":"review","venue":"Expert Opinion on Drug Safety","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":316,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Ethambutol; Incidence (geometry); Pyrazinamide; Isoniazid; Discontinuation; Adverse effect; Tuberculosis; Hepatitis; Internal medicine; Intensive care medicine; Pathology","score_opus":0.17355412632767034,"score_gpt":0.47612585258496404,"score_spread":0.30257172625729367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012393743","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000014015217,0.94566315,0.0002727268,0.0028077539,0.014711889,0.003757141,0.00078962947,0.00060103275,0.031382684],"genre_scores_gemma":[0.00009355773,0.9877665,0.00020236833,0.002068165,0.0031543132,0.0010168909,0.0009490897,0.00015531758,0.004593775],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99462736,0.0013864421,0.0014950528,0.001183856,0.00044788982,0.00085942907],"domain_scores_gemma":[0.9968774,0.0010392279,0.0005788879,0.00082413777,0.00013093636,0.0005494512],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0012944455,0.0010298939,0.001749884,0.000707262,0.0012038953,0.00003826361,0.00064549973,0.001537361,0.0014454171],"category_scores_gemma":[0.00016658485,0.0009647126,0.001039064,0.0010416629,0.00012478988,0.00020963549,0.00020961383,0.0027099594,0.0042883093],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018666127,0.0007497972,0.000002693802,0.0020083522,0.00032266777,0.000014696827,0.00077228836,0.00077968516,0.00000784601,0.0009474335,0.063205555,0.9310023],"study_design_scores_gemma":[0.0007311436,0.00010940028,0.0000044085464,0.003565574,0.000110068795,0.00003509745,0.000050767547,0.00010307382,0.00016244927,0.000038213322,0.9940968,0.0009930157],"about_ca_topic_score_codex":0.0005385311,"about_ca_topic_score_gemma":0.000091711576,"teacher_disagreement_score":0.9308912,"about_ca_system_score_codex":0.000965856,"about_ca_system_score_gemma":0.00028668166,"threshold_uncertainty_score":0.99975884},"labels":[],"label_agreement":null},{"id":"W2014107536","doi":"10.1016/j.fct.2012.12.063","title":"Models of drug-induced liver injury for evaluation of phytotherapeutics and other natural products","year":2013,"lang":"en","type":"review","venue":"Food and Chemical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":121,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; McGill University; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; National Center for Research Resources; National Institute of General Medical Sciences","keywords":"Acetaminophen; Liver injury; Thioacetamide; Pharmacology; Lipid peroxidation; Carbon tetrachloride; Drug; Detoxification (alternative medicine); Programmed cell death; Medicine; Apoptosis; Chemistry; Oxidative stress; Biochemistry; Pathology","score_opus":0.33234654780665907,"score_gpt":0.46832979489121845,"score_spread":0.1359832470845594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014107536","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10784745,0.88662076,0.000011379947,0.00006766804,0.0008459676,0.003909756,0.0002898206,0.000032437274,0.0003747529],"genre_scores_gemma":[0.28715298,0.71044475,0.00034022835,0.00027261104,0.00048666575,0.0010677886,0.00005612678,0.000076600074,0.000102266924],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973458,0.0007376852,0.0007735602,0.00055777776,0.00020534739,0.00037981715],"domain_scores_gemma":[0.9980632,0.0005526394,0.00066893053,0.0002317681,0.00037138964,0.00011204085],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0011505085,0.00043910125,0.0014403915,0.00017926912,0.00008624969,0.000009596847,0.00021157922,0.0013387218,0.00006516836],"category_scores_gemma":[0.00015868549,0.00037883827,0.00021602238,0.00020741462,0.00033165756,0.00010008833,0.00011096188,0.00091210817,0.0000036067713],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014381633,0.00032046833,0.0000024530084,0.010608007,0.0006244254,2.2698468e-7,0.00037060046,0.0000017063234,0.051326677,0.0012304555,0.00024636832,0.9351248],"study_design_scores_gemma":[0.0029126562,0.00096787326,0.0000018465936,0.0011010945,0.004032023,0.000058859685,0.000054498294,0.004193227,0.37055302,0.006745366,0.60853875,0.0008407791],"about_ca_topic_score_codex":0.000007417787,"about_ca_topic_score_gemma":0.000005520648,"teacher_disagreement_score":0.93428403,"about_ca_system_score_codex":0.00008378325,"about_ca_system_score_gemma":0.0002580951,"threshold_uncertainty_score":0.99995774},"labels":[],"label_agreement":null},{"id":"W2015021844","doi":"10.3109/00498254.2013.867553","title":"Chimeric rodents with humanized liver: bridging the preclinical/clinical trial gap in ADME/toxicity studies","year":2013,"lang":"en","type":"review","venue":"Xenobiotica","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; KMT Hepatech (Canada)","funders":"","keywords":"Humanized mouse; ADME; Biology; Toxicity; In vivo; Animal studies; Human liver; Pharmacology; Computational biology; Medicine; Pharmacokinetics; In vitro; Biotechnology; Internal medicine; Biochemistry","score_opus":0.7052087876482531,"score_gpt":0.6005807466186256,"score_spread":0.10462804102962753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015021844","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.006319501,0.9776171,0.000023344242,0.00037419953,0.0048069237,0.008937739,0.000055538785,0.00021322281,0.0016524305],"genre_scores_gemma":[0.005012081,0.98960096,0.000121379344,0.0008227955,0.0024840778,0.0008401907,0.000043170035,0.00011356205,0.00096178084],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9877992,0.007186059,0.00241358,0.0012119066,0.00041418298,0.00097503857],"domain_scores_gemma":[0.992155,0.0052130665,0.0013258618,0.0008145943,0.00017855348,0.0003129088],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0057950313,0.00094136974,0.003419627,0.0002667309,0.00070450426,0.00010666435,0.0011246422,0.0019360498,0.0006769505],"category_scores_gemma":[0.0016196917,0.0005904009,0.00085561135,0.0007739083,0.000990453,0.00018686689,0.00046746866,0.006871669,0.0012596998],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029385828,0.0015409277,0.00010760122,0.0046107196,0.0021656835,0.00008769481,0.0004105727,0.000008153928,0.0000046015234,0.00018702375,0.0020456335,0.98589283],"study_design_scores_gemma":[0.016335692,0.0010027399,0.0000650744,0.003627893,0.0030222144,0.00008087935,0.000071360286,0.00021511907,0.00003687086,0.00013638817,0.9744639,0.00094188575],"about_ca_topic_score_codex":0.00007259625,"about_ca_topic_score_gemma":0.00019548254,"teacher_disagreement_score":0.9849509,"about_ca_system_score_codex":0.00030838078,"about_ca_system_score_gemma":0.0005644939,"threshold_uncertainty_score":0.9996547},"labels":[],"label_agreement":null},{"id":"W2015705139","doi":"10.1038/labinvest.2008.75","title":"The Nrf2 transcription factor protects from toxin-induced liver injury and fibrosis","year":2008,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":195,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Sinai Hospital","funders":"China Scholarship Council; Eidgenössische Technische Hochschule Zürich; Deutsche Forschungsgemeinschaft; Shandong University; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Hepatotoxin; Fibrosis; Liver injury; Cirrhosis; Toxin; Inflammation; Transcription factor; Steatosis; Detoxification (alternative medicine); Medicine; Knockout mouse; Cancer research; Biology; Immunology; Pharmacology; Pathology; Internal medicine; Toxicity; Gene; Biochemistry; Receptor","score_opus":0.1363405124419441,"score_gpt":0.35087575464100496,"score_spread":0.21453524219906087,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015705139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99607825,0.0004155618,0.00006569974,0.00094601116,0.001018912,0.00089173246,0.00019907314,0.00018956822,0.00019521854],"genre_scores_gemma":[0.9969193,0.00046783307,0.00018919504,0.0016157688,0.00040217853,0.00021560819,0.000035639907,0.000026095498,0.00012841239],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99792683,0.0008738959,0.00032353305,0.00035510867,0.00021378545,0.000306837],"domain_scores_gemma":[0.9989486,0.00024333304,0.00017846486,0.0002121242,0.00017575866,0.00024172469],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.00042593584,0.00023581562,0.0001800786,0.000075693715,0.0013718456,0.000054511012,0.00015011616,0.0005126566,0.000114084476],"category_scores_gemma":[0.0001793461,0.00020285088,0.000047643276,0.00036477073,0.00034542303,0.00047703105,0.00002710405,0.00087199826,0.0001060542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016257961,0.00003736899,0.0041347817,0.000025824836,0.000048969174,0.0000063256007,0.0033377632,0.0000068492063,0.97849953,0.0004333123,0.0006738626,0.012632858],"study_design_scores_gemma":[0.0006813445,0.00015500796,0.04882997,0.000023539478,0.000037655875,0.0000051250786,0.000102850565,0.000902978,0.9018885,0.0013344705,0.045765057,0.00027353872],"about_ca_topic_score_codex":0.00019408544,"about_ca_topic_score_gemma":0.00013334068,"teacher_disagreement_score":0.07661104,"about_ca_system_score_codex":0.00010813217,"about_ca_system_score_gemma":0.00017863871,"threshold_uncertainty_score":0.99992824},"labels":[],"label_agreement":null},{"id":"W2016473413","doi":"10.1111/j.1572-0241.2003.07562.x","title":"Early Onset, Nefazodone-Induced Fulminant Hepatic Failure","year":2003,"lang":"en","type":"letter","venue":"The American Journal of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Nefazodone; Fulminant hepatic failure; Fulminant; Intensive care medicine; Internal medicine; Liver transplantation","score_opus":0.06083849652519673,"score_gpt":0.3592208010659537,"score_spread":0.298382304540757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016473413","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.706412,0.00006739357,0.00022363948,0.29011303,0.0026307513,0.00037220636,0.000038622307,0.000027270169,0.00011508706],"genre_scores_gemma":[0.56224823,0.00015102822,0.00018194267,0.43460053,0.0024353643,0.00003153143,0.000010413253,0.000074405,0.00026655418],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99023813,0.0063194055,0.001283157,0.00043028832,0.00047535403,0.0012536709],"domain_scores_gemma":[0.9948368,0.00070148864,0.0033024482,0.0005662889,0.000328722,0.00026422093],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0021098226,0.00067871605,0.0017252004,0.0005181617,0.00039948995,0.000049728176,0.0012955647,0.0008320921,0.00036494058],"category_scores_gemma":[0.00015240317,0.00049612945,0.0006588578,0.0003675151,0.0010389604,0.00015372036,0.00012496153,0.011790357,0.00017266677],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013257967,0.0004763285,0.024557177,0.00014216754,0.0032300476,0.0039794417,0.0016367339,0.00011105901,0.006416658,0.000011610345,0.93255,0.013630793],"study_design_scores_gemma":[0.0037192772,0.029794496,0.006540406,0.00015970564,0.0019576026,0.019068163,0.00047454238,0.00008985573,0.0028076973,0.00076310453,0.9338512,0.0007739476],"about_ca_topic_score_codex":0.0001470466,"about_ca_topic_score_gemma":0.00007862062,"teacher_disagreement_score":0.14448752,"about_ca_system_score_codex":0.00025846672,"about_ca_system_score_gemma":0.00024086937,"threshold_uncertainty_score":0.999749},"labels":[],"label_agreement":null},{"id":"W2017000072","doi":"10.3109/15563650.2014.946994","title":"Extracorporeal treatment for acetaminophen poisoning: Recommendations from the EXTRIP workgroup","year":2014,"lang":"en","type":"review","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":127,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto; Université de Montréal; McGill University Health Centre","funders":"","keywords":"Workgroup; Medicine; Acetaminophen; Extracorporeal; Observational study; Intensive care medicine; Surgery; Internal medicine; Pharmacology","score_opus":0.6450323486708766,"score_gpt":0.6048988018596422,"score_spread":0.04013354681123438,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017000072","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00024350369,0.9632117,0.0020266306,0.004074634,0.01816035,0.0073424918,0.001355189,0.00030915096,0.0032763316],"genre_scores_gemma":[0.00022119099,0.97811127,0.0010830534,0.0033359793,0.00744245,0.004035113,0.0016827593,0.00013383316,0.003954349],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9879818,0.0067933714,0.0027259628,0.0013534639,0.00015040032,0.0009950273],"domain_scores_gemma":[0.96267873,0.034112513,0.0016793335,0.0009357729,0.00012178319,0.00047188823],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0042049084,0.00094403466,0.003370383,0.00014611788,0.0010280008,0.000076482225,0.0011328936,0.0044139843,0.0018167702],"category_scores_gemma":[0.0018612589,0.0006504517,0.0021512047,0.00035905183,0.00066317717,0.00009502865,0.00022600061,0.0034047686,0.0010237579],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001774127,0.00087187684,0.00010083143,0.00036809922,0.0012301814,0.00001038716,0.00008993988,0.0000036643744,0.0000036187882,0.0014128926,0.023452448,0.97227865],"study_design_scores_gemma":[0.002185678,0.0011642964,0.00004839429,0.0005889609,0.0035987117,0.000029489403,0.000027433478,0.00020634742,0.00001218587,0.0023246692,0.989182,0.0006318441],"about_ca_topic_score_codex":0.000053291962,"about_ca_topic_score_gemma":0.00023640663,"teacher_disagreement_score":0.9716468,"about_ca_system_score_codex":0.0005056981,"about_ca_system_score_gemma":0.00062922615,"threshold_uncertainty_score":0.9997541},"labels":[],"label_agreement":null},{"id":"W2017154492","doi":"10.1038/tpj.2010.5","title":"Genetic variation in carboxylesterase genes and susceptibility to isoniazid-induced hepatotoxicity","year":2010,"lang":"en","type":"article","venue":"The Pharmacogenomics Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Centre for Disease Control; Vancouver Coastal Health Research Institute; Simon Fraser University; Vancouver Coastal Health; Canada's Michael Smith Genome Sciences Centre","funders":"Bundesinstitut für Sportwissenschaft","keywords":"Single-nucleotide polymorphism; Biology; Genetics; Candidate gene; Linkage disequilibrium; Gene; Genetic variation; Genotype; Genetic association; Exon","score_opus":0.08571265276300732,"score_gpt":0.39341105844304936,"score_spread":0.30769840568004203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017154492","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99259233,0.00015950929,0.00042466115,0.0025059504,0.0030053284,0.000985038,0.000031559015,0.00004777527,0.0002478677],"genre_scores_gemma":[0.9951168,0.00039480827,0.0004930002,0.0026333851,0.0012224624,0.00006152084,0.0000014310546,0.000037125697,0.000039514678],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99714047,0.00097263634,0.0006479462,0.00041149187,0.00020552363,0.0006219475],"domain_scores_gemma":[0.9984899,0.0003178423,0.00024874858,0.00028310454,0.00013362172,0.00052677165],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.003312769,0.00031575872,0.00030942875,0.0002546573,0.00075579714,0.00012900968,0.00047663384,0.00034291518,0.0003649045],"category_scores_gemma":[0.00014723798,0.00026881398,0.00010506742,0.0003437897,0.000116784366,0.00020710766,0.0001681309,0.0031002436,0.00008499472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034333338,0.000190901,0.030629877,0.000015824833,0.00006404877,0.00004264858,0.002359774,0.0007919577,0.91775,0.00008835202,0.000050977396,0.04767231],"study_design_scores_gemma":[0.0064504603,0.00039434127,0.24725841,0.000028972889,0.00037879136,0.0026596433,0.000285008,0.044109274,0.6610489,0.0054885685,0.03059802,0.0012995967],"about_ca_topic_score_codex":0.00027595204,"about_ca_topic_score_gemma":0.0012684474,"teacher_disagreement_score":0.25670108,"about_ca_system_score_codex":0.00021913082,"about_ca_system_score_gemma":0.00018876561,"threshold_uncertainty_score":0.9999764},"labels":[],"label_agreement":null},{"id":"W2017494004","doi":"10.1592/phco.21.1.60.34442","title":"Misoprostol Therapeutics Revisited","year":2001,"lang":"en","type":"review","venue":"Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Pharmacology; Internal medicine; Gastroenterology","score_opus":0.23777926916107953,"score_gpt":0.5018196363861005,"score_spread":0.264040367225021,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017494004","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004136159,0.9869968,0.000041295174,0.0008951665,0.0039344802,0.0026651598,0.00007918219,0.00012066074,0.0011310453],"genre_scores_gemma":[0.0013253988,0.98405546,0.000028435628,0.00842188,0.0037851562,0.00014050069,0.000025665093,0.00023354654,0.001983947],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.987102,0.008226881,0.0024642122,0.00060623174,0.00053264375,0.001068069],"domain_scores_gemma":[0.99311006,0.0022372687,0.003252407,0.0004641604,0.00042367628,0.00051241287],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0065771076,0.0013901293,0.0030400008,0.00085897563,0.0015936355,0.00010067142,0.0018063078,0.0011799469,0.0038870976],"category_scores_gemma":[0.00001849693,0.00090706913,0.0011739881,0.0010044877,0.0009821468,0.00040444662,0.00014025262,0.0067325947,0.000088040026],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013085073,0.00084556395,0.000029908651,0.001384358,0.004347207,0.0001595884,0.0019526636,0.000011009866,0.013373831,0.000088266235,0.026230823,0.95026827],"study_design_scores_gemma":[0.005402628,0.00058031385,0.0000029458417,0.00075562205,0.004360943,0.0019666632,0.0000928712,0.000031667925,0.0049620243,0.0006197798,0.98034376,0.00088080304],"about_ca_topic_score_codex":0.00001595006,"about_ca_topic_score_gemma":0.0000036129595,"teacher_disagreement_score":0.9541129,"about_ca_system_score_codex":0.00026681795,"about_ca_system_score_gemma":0.00042199268,"threshold_uncertainty_score":0.9998849},"labels":[],"label_agreement":null},{"id":"W2020148836","doi":"10.3109/15563650.2010.523828","title":"When do the aminotransferases rise after acute acetaminophen overdose?","year":2010,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Sunnybrook Health Science Centre; University of Calgary; Health Sciences Centre; Queen's University","funders":"","keywords":"Medicine; Acetaminophen; Ingestion; Retrospective cohort study; Context (archaeology); acetaminophen overdose; Anesthesia; Coagulopathy; Cohort; Internal medicine; Acetylcysteine; Gastroenterology","score_opus":0.14171137825901714,"score_gpt":0.47219291050505463,"score_spread":0.3304815322460375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020148836","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97154784,0.00022335793,0.00021019108,0.008526811,0.011443787,0.0011348635,0.00012301414,0.00022169093,0.006568455],"genre_scores_gemma":[0.9799588,0.00039594003,0.0003613294,0.014348799,0.00233284,0.00045914607,0.000014807361,0.000050575018,0.0020777653],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9950254,0.0020200475,0.0010530304,0.000791493,0.00022541717,0.0008846125],"domain_scores_gemma":[0.9951962,0.0031876483,0.00023236973,0.00075957074,0.0001388918,0.00048526714],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0030095316,0.00042512684,0.0006544537,0.000103713704,0.0005938825,0.00007059323,0.00084997097,0.0021001738,0.008760419],"category_scores_gemma":[0.00078730914,0.00031754383,0.00047703672,0.00023347996,0.0015796166,0.0002127542,0.00024879322,0.0055739037,0.001694895],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007224045,0.005585022,0.25987732,0.0001221949,0.00271063,0.0009892603,0.003251664,0.000059425416,0.21548809,0.024244508,0.04211411,0.43833372],"study_design_scores_gemma":[0.0031318208,0.00076208386,0.07045748,0.000009677584,0.0006032794,0.00016980291,0.00005816029,0.00047204553,0.023577146,0.010373317,0.8898028,0.0005823819],"about_ca_topic_score_codex":0.00002735942,"about_ca_topic_score_gemma":0.0002891569,"teacher_disagreement_score":0.8476887,"about_ca_system_score_codex":0.00006995389,"about_ca_system_score_gemma":0.00018634702,"threshold_uncertainty_score":0.99992764},"labels":[],"label_agreement":null},{"id":"W2020660959","doi":"10.1016/s0197-0186(00)00062-0","title":"Evidence for a serotonin transporter deficit in experimental acute liver failure","year":2001,"lang":"en","type":"article","venue":"Neurochemistry International","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Saint-Luc; Université de Montréal","funders":"Medical Research Council","keywords":"Serotonin; Serotonin transporter; Citalopram; Hepatic encephalopathy; Dorsal raphe nucleus; Internal medicine; Endocrinology; 5-Hydroxyindoleacetic acid; Medicine; Serotonergic; Neuroscience; Biology; Cirrhosis","score_opus":0.21536731345153487,"score_gpt":0.4566577382778004,"score_spread":0.2412904248262655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020660959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941523,0.00010542458,0.00048824318,0.0014289352,0.0006946792,0.00046822696,0.00005322999,0.000059596718,0.002549345],"genre_scores_gemma":[0.99639565,0.00014172532,0.00021192338,0.0011811013,0.00032886735,0.0004161836,0.00005582211,0.0000169419,0.0012518135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892116,0.00005210926,0.0002623633,0.00034461624,0.00016116345,0.00025858328],"domain_scores_gemma":[0.99949396,0.00015950325,0.00008155457,0.00010391358,0.00007107245,0.00008997663],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00017827784,0.00016851492,0.00013044498,0.00006517447,0.000094359384,0.000024598123,0.00029801455,0.00026527786,0.0017801672],"category_scores_gemma":[0.000053282816,0.00019009506,0.000105881314,0.00009945317,0.000054254826,0.0002159337,0.000029269135,0.00053619547,0.00004544717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00094817864,0.0003048376,0.013157706,0.00002825933,0.00006441515,0.00015156799,0.00039368542,0.00016485532,0.98191863,0.000097190634,0.00070683286,0.002063817],"study_design_scores_gemma":[0.0017884893,0.000074458745,0.0028433145,0.0000536065,0.000033628374,0.00024135712,0.00008214216,0.0055743125,0.93102217,0.000075786345,0.057980973,0.00022979258],"about_ca_topic_score_codex":0.000014820555,"about_ca_topic_score_gemma":0.000026974883,"teacher_disagreement_score":0.05727414,"about_ca_system_score_codex":0.00012648477,"about_ca_system_score_gemma":0.000045655725,"threshold_uncertainty_score":0.99913234},"labels":[],"label_agreement":null},{"id":"W2020691793","doi":"10.14740/jmc.v6i1.2009","title":"Hepatotoxicity and Anti-Nuclear Antibody Positivity During Methimazole Therapy for Thyrotoxicosis: A Case Report","year":2015,"lang":"en","type":"article","venue":"Journal of Medical Cases","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Methimazole; Medicine; Thyroid; Gastroenterology; Internal medicine; Antibody; Endocrine system; Adverse effect; Autoimmune hepatitis; Drug; Antithyroid drugs; Hepatitis; Graves' disease; Pharmacology; Immunology; Hormone","score_opus":0.1913364429153894,"score_gpt":0.4780187107405759,"score_spread":0.28668226782518647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020691793","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993221,0.0013597651,0.00043743633,0.0030139745,0.0011393673,0.00059562724,0.00003581182,0.000046145684,0.00015090872],"genre_scores_gemma":[0.996568,0.0008978756,0.00033798817,0.0011780338,0.0009388212,0.000021525293,0.0000037884581,0.000028850309,0.000025100031],"study_design_codex":"case_report","study_design_gemma":"case_report","domain_scores_codex":[0.99714965,0.0007693137,0.00076364004,0.00025848148,0.00067477225,0.00038414582],"domain_scores_gemma":[0.9971593,0.00078145927,0.0005869391,0.00015308298,0.00036159618,0.000957631],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006172306,0.00023414317,0.00055254885,0.00019048015,0.0004062183,0.0000530539,0.00020824393,0.0006233902,0.00014905291],"category_scores_gemma":[0.0025448261,0.00019136877,0.00021070198,0.00017796384,0.00024819598,0.00034011732,0.00009147724,0.0014362526,0.0000048023007],"study_design_candidate":"case_report","study_design_consensus":"case_report","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008320417,0.0039950614,0.03431332,0.00053744746,0.0014290533,0.60505533,0.004280439,0.00012277687,0.2865277,0.00055309926,0.0055055628,0.04935981],"study_design_scores_gemma":[0.0097501455,0.0016452031,0.002569991,0.00015723347,0.0002610731,0.7680013,0.0010580812,0.0026501648,0.17914158,0.0005180702,0.03378105,0.00046608644],"about_ca_topic_score_codex":0.00012199404,"about_ca_topic_score_gemma":0.00002752665,"teacher_disagreement_score":0.16294599,"about_ca_system_score_codex":0.000102334365,"about_ca_system_score_gemma":0.000338515,"threshold_uncertainty_score":0.78037924},"labels":[],"label_agreement":null},{"id":"W2021838863","doi":"10.1016/s1098-3015(10)70844-5","title":"PMS42 A COMPARISON OF PROVINCIAL PRESCRIPTION-ONLY PHARMACEUTICAL DATABASE WITH SELF-REPORTED USAGE OF ACETAMINOPHEN AND NSAIDS ACCORDING TO OSTEOARTHRITIS STAGE IN BRITISH COLUMBIA","year":2008,"lang":"en","type":"article","venue":"Value in Health","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Acetaminophen; Medical prescription; Medicine; Stage (stratigraphy); Osteoarthritis; Database; Alternative medicine; Pharmacology; Computer science","score_opus":0.16174659231288674,"score_gpt":0.41356990151361844,"score_spread":0.2518233092007317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021838863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99609685,0.0005718884,0.00012322962,0.00012409594,0.0002959379,0.002251309,0.0003096652,0.000054097294,0.00017290564],"genre_scores_gemma":[0.99733657,0.0004524192,0.001624899,0.0002723119,0.000066986104,0.00010925326,0.000028304165,0.000025018224,0.000084222265],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9964948,0.001148497,0.0010697681,0.0004593803,0.00030135908,0.00052614626],"domain_scores_gemma":[0.9987017,0.00029638785,0.00039640407,0.00019810963,0.00009461201,0.00031281385],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0018493184,0.00016828241,0.0006657298,0.00021956828,0.00022721902,0.000024121731,0.00015804236,0.00024385961,0.000082470586],"category_scores_gemma":[0.00018670505,0.0002506861,0.00003981016,0.0006542256,0.00020268136,0.00025709116,0.000105737265,0.0009800323,0.000002650455],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005340402,0.0011161173,0.95230466,0.0010055507,0.000053007458,0.00016912224,0.0036450997,0.0012203421,0.010961211,0.000028741342,0.000092809634,0.028869284],"study_design_scores_gemma":[0.025155408,0.006494948,0.85717165,0.0023955747,0.00022425302,0.0013116274,0.0035007945,0.046082374,0.04046556,0.0001118953,0.015666688,0.001419225],"about_ca_topic_score_codex":0.075149216,"about_ca_topic_score_gemma":0.06525033,"teacher_disagreement_score":0.09513302,"about_ca_system_score_codex":0.00021808632,"about_ca_system_score_gemma":0.00073335745,"threshold_uncertainty_score":0.9999945},"labels":[],"label_agreement":null},{"id":"W2021961666","doi":"10.1021/tx300341r","title":"Direct Oxidation and Covalent Binding of Isoniazid to Rodent Liver and Human Hepatic Microsomes: Humans Are More Like Mice than Rats","year":2012,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":106,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Metabolite; Liver injury; Chemistry; Microsome; Toxicity; Alanine transaminase; Sorbitol dehydrogenase; Pharmacology; Biochemistry; Endocrinology; Enzyme; Biology","score_opus":0.26113172051759775,"score_gpt":0.49809019512207975,"score_spread":0.236958474604482,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021961666","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962562,0.0008023117,0.000010076549,0.0010668373,0.00027042994,0.0009988575,0.00003426217,0.00003332435,0.00052772777],"genre_scores_gemma":[0.99844724,0.00042762718,0.00013598903,0.0003778327,0.0001751017,0.00019698199,0.000020040949,0.000026647369,0.00019255963],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99691665,0.0009902512,0.00043397496,0.00047234236,0.00027733814,0.00090947043],"domain_scores_gemma":[0.9981376,0.00093285146,0.00013008076,0.00019915457,0.0001288229,0.00047151712],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0025969604,0.00022354454,0.00043199304,0.00048732242,0.00031345265,0.000025844307,0.00024683657,0.0006218104,0.0001482375],"category_scores_gemma":[0.00040923525,0.00022891434,0.0000507938,0.0004731421,0.00060275797,0.00018222888,0.0003980631,0.0012973469,0.000042023366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023163544,0.00054333376,0.073927544,0.00031032678,0.000043404805,0.000015515316,0.0023303903,0.0000048767884,0.92013603,0.00020730414,0.0004036684,0.0018459612],"study_design_scores_gemma":[0.0008594475,0.00025121792,0.03899535,0.000105532454,0.00002948568,0.000025094472,0.00044022195,0.0001220794,0.95396656,0.00011283446,0.004864981,0.0002272096],"about_ca_topic_score_codex":0.00017072508,"about_ca_topic_score_gemma":0.00017971412,"teacher_disagreement_score":0.034932196,"about_ca_system_score_codex":0.00031519838,"about_ca_system_score_gemma":0.000049152986,"threshold_uncertainty_score":0.9334856},"labels":[],"label_agreement":null},{"id":"W2022313385","doi":"10.1186/cc8776","title":"Drug-induced hepatic cholestasis in the ICU: a case-control study","year":2010,"lang":"en","type":"article","venue":"Critical Care","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Hôpital du Sacré-Cœur de Montréal","funders":"","keywords":"Medicine; Cholestasis; Alkaline phosphatase; Internal medicine; Drug; Liver injury; Gastroenterology; Intensive care medicine; Pharmacology","score_opus":0.11916729901220817,"score_gpt":0.45965670103865575,"score_spread":0.34048940202644756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022313385","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98999166,0.00008782965,0.00002557345,0.0024322919,0.0018422682,0.0015711259,0.00009118081,0.00009305274,0.0038650078],"genre_scores_gemma":[0.99592835,0.0000019843437,0.00002798906,0.0030200263,0.0004717287,0.00049938133,0.000004566208,0.00002461214,0.000021337519],"study_design_codex":"design_other","study_design_gemma":"qualitative","domain_scores_codex":[0.99666977,0.0017291431,0.00037582073,0.00041414748,0.0002434384,0.00056767557],"domain_scores_gemma":[0.99749106,0.0016807909,0.000041594656,0.00040478347,0.00017202465,0.00020976023],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.001625522,0.00025463256,0.00029191675,0.00013085485,0.0005951789,0.00007921891,0.000366172,0.00040487,0.00054074195],"category_scores_gemma":[0.0010347124,0.00020200323,0.00011841536,0.00035563484,0.00019230972,0.00015296003,0.00005252316,0.0031123753,0.00017560368],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009196226,0.007849836,0.3625249,0.0009086541,0.00029203587,0.025085937,0.14663924,0.00006295919,0.07689766,0.014541642,0.00091701857,0.3633605],"study_design_scores_gemma":[0.04160111,0.0047918684,0.34741926,0.00017968447,0.0045001796,0.011897562,0.38705167,0.010488031,0.10408554,0.012288871,0.07020004,0.005496181],"about_ca_topic_score_codex":0.00032550903,"about_ca_topic_score_gemma":0.0053872266,"teacher_disagreement_score":0.35786432,"about_ca_system_score_codex":0.000068381625,"about_ca_system_score_gemma":0.00007853137,"threshold_uncertainty_score":0.99918747},"labels":[],"label_agreement":null},{"id":"W2022497572","doi":"10.1016/s0378-4274(00)00218-6","title":"The role of mitochondrial injury in bromobenzene and furosemide induced hepatotoxicity","year":2000,"lang":"en","type":"article","venue":"Toxicology Letters","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Liver Foundation","keywords":"Bromobenzene; Glutathione; Chemistry; Respiration; Glutathione disulfide; Biochemistry; Mitochondrion; Furosemide; Pharmacology; Biology; Enzyme","score_opus":0.03853126371128835,"score_gpt":0.3525171950945213,"score_spread":0.31398593138323294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022497572","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925177,0.00023218973,0.0000057892003,0.0027849262,0.0008839374,0.0008139077,0.000025119878,0.000070955604,0.0026654697],"genre_scores_gemma":[0.9951683,0.0003617984,0.00008433453,0.0037879385,0.00026997444,0.00015996542,0.000005091915,0.00002704203,0.00013552925],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99698156,0.001126865,0.00061724964,0.00044019043,0.00016769397,0.00066642667],"domain_scores_gemma":[0.9987064,0.0006091571,0.00018427832,0.00029805087,0.00003248962,0.0001696278],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00088238827,0.00028754355,0.00041100523,0.00017250505,0.00042351693,0.000023656914,0.0003627061,0.0006573984,0.0005705822],"category_scores_gemma":[0.000121129604,0.00025466885,0.000099514014,0.00035426294,0.0004747751,0.00016072545,0.000087073895,0.0014444859,0.00007431051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00092365546,0.00019162887,0.012177101,0.000013951294,0.000059966304,0.000017689925,0.0005689043,0.00006637792,0.8787722,0.0004255387,0.0003122156,0.1064708],"study_design_scores_gemma":[0.0022214178,0.00039598552,0.018545264,0.000021747672,0.00005930368,0.00006378042,0.000114149516,0.0010320366,0.9016536,0.002247841,0.073228724,0.00041618754],"about_ca_topic_score_codex":0.00022279735,"about_ca_topic_score_gemma":0.00028940273,"teacher_disagreement_score":0.10605461,"about_ca_system_score_codex":0.00011325288,"about_ca_system_score_gemma":0.00006814532,"threshold_uncertainty_score":0.9999906},"labels":[],"label_agreement":null},{"id":"W2023946039","doi":"10.1016/s0009-9236(03)90454-1","title":"Response Surface Analysis of Acetaminophen (APAP) Overdose Hepatotoxicity — Unmasking the Data","year":2003,"lang":"en","type":"article","venue":"Clinical Pharmacology & Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Purdue Pharma (Canada)","funders":"","keywords":"Acetaminophen; acetaminophen overdose; Drug overdose; Pharmacology; Medicine; Clinical pharmacology; Chemistry; Emergency medicine; Poison control; Acetylcysteine; Biochemistry","score_opus":0.46546555481481916,"score_gpt":0.55060402799214,"score_spread":0.08513847317732087,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023946039","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98601043,0.00093580235,0.0007495385,0.0049355105,0.004744923,0.0011279032,0.00036223355,0.00015179848,0.0009818497],"genre_scores_gemma":[0.9541241,0.0015675804,0.00040473085,0.043019075,0.00027225682,0.000034693774,0.00006848344,0.000056109595,0.0004529884],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9821878,0.013772359,0.0016940073,0.0010401867,0.00041363412,0.00089197606],"domain_scores_gemma":[0.98687935,0.009751815,0.0011904313,0.001527943,0.000299674,0.00035076155],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.01476198,0.00052384875,0.0011935986,0.00026049948,0.0007308044,0.0000345027,0.0019255138,0.0011936914,0.0017647869],"category_scores_gemma":[0.00062156067,0.0004263392,0.0006068105,0.0020429941,0.0015764944,0.0002649691,0.0005007203,0.0030662657,0.00012181432],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015336339,0.0068246294,0.33262512,0.000110236455,0.048472777,0.0001436593,0.003205335,0.01727669,0.5401501,0.001061863,0.016753422,0.018039806],"study_design_scores_gemma":[0.006004256,0.0006924945,0.048715103,0.000016883863,0.02466598,0.000031592706,0.00041711834,0.06862703,0.16421041,0.0006024428,0.68502176,0.0009949252],"about_ca_topic_score_codex":0.000032526434,"about_ca_topic_score_gemma":0.00004339261,"teacher_disagreement_score":0.6682683,"about_ca_system_score_codex":0.00014620827,"about_ca_system_score_gemma":0.00045590408,"threshold_uncertainty_score":0.99981886},"labels":[],"label_agreement":null},{"id":"W2024570055","doi":"10.1016/j.pharma.2013.03.001","title":"Patients’ knowledge about paracetamol (acetaminophen): A study in a French hospital emergency department","year":2013,"lang":"en","type":"article","venue":"Annales Pharmaceutiques Françaises","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Medicine; Emergency department; Acetaminophen; Antipyretic; Health professionals; Ambulatory; Analgesic; Medical emergency; Health care; Emergency medicine; Anesthesia; Surgery; Nursing","score_opus":0.09062711702180545,"score_gpt":0.4179104154738628,"score_spread":0.3272832984520574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024570055","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9771902,0.003949308,0.00002422895,0.00035149866,0.0026670387,0.005532571,0.000076298755,0.00034460454,0.009864264],"genre_scores_gemma":[0.9929614,0.0016702454,0.000056696786,0.00058278604,0.0003966619,0.0031038877,0.00007729176,0.000075727665,0.001075286],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99507546,0.0013610615,0.001126225,0.00091498776,0.00037339312,0.0011488813],"domain_scores_gemma":[0.9980684,0.0002351073,0.00033553172,0.00041987677,0.00041593183,0.000525169],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0009027126,0.00071168866,0.00067326834,0.0004398586,0.0005813878,0.0000746808,0.0006152732,0.0004909085,0.0051788897],"category_scores_gemma":[0.00013177209,0.00070071436,0.00026887745,0.0007592913,0.00022099861,0.00088152144,0.0002424393,0.001653439,0.0022463787],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013314799,0.010608752,0.88925254,0.00014428947,0.00030997526,0.000044048644,0.011623081,0.00005956548,0.0017303551,0.000048492908,0.011119974,0.0749258],"study_design_scores_gemma":[0.005579754,0.0011868968,0.78527796,0.00005565409,0.0002083956,0.00000617338,0.0006928307,0.0012803114,0.019870035,0.00035075832,0.18434066,0.0011505935],"about_ca_topic_score_codex":0.00096903136,"about_ca_topic_score_gemma":0.0009318861,"teacher_disagreement_score":0.17322068,"about_ca_system_score_codex":0.00019717817,"about_ca_system_score_gemma":0.00012067022,"threshold_uncertainty_score":0.9995444},"labels":[],"label_agreement":null},{"id":"W2024731860","doi":"10.3109/15563650.2014.902956","title":"Four-hour acetaminophen concentration estimation after ingested dose based on pharmacokinetic models","year":2014,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Acetaminophen; Ingestion; Medicine; Pharmacokinetics; Bioavailability; Volume of distribution; Referral; acetaminophen overdose; Anesthesia; Emergency medicine; Pharmacology; Acetylcysteine; Internal medicine; Chemistry","score_opus":0.26956933169057246,"score_gpt":0.477664773530191,"score_spread":0.20809544183961853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024731860","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9499217,0.000050180788,0.0262886,0.0038192694,0.005172064,0.0015432513,0.000032621432,0.00038267806,0.012789587],"genre_scores_gemma":[0.97704643,0.000066444445,0.0012073,0.019827299,0.0010161246,0.00041607747,0.00005228431,0.000050470888,0.00031758068],"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99363565,0.0035106018,0.0010878822,0.0007899609,0.00026829072,0.0007075986],"domain_scores_gemma":[0.99567527,0.0028586702,0.0004114214,0.00042975936,0.00016201328,0.00046284957],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0030496833,0.00040544302,0.000623755,0.00015316895,0.00031164195,0.000042124822,0.00034602435,0.0013834826,0.001191194],"category_scores_gemma":[0.0010542225,0.00040267047,0.00026126258,0.0003021579,0.00041590442,0.00025012015,0.00007837501,0.0020021242,0.00073261023],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007707966,0.0035952744,0.013164107,0.0001954541,0.00029295534,0.00010984314,0.00043969054,0.29678857,0.018146345,0.004024425,0.003508235,0.65202713],"study_design_scores_gemma":[0.0059224567,0.0014651614,0.013116281,0.00003553366,0.00021252493,0.000013214475,0.000007596904,0.93477386,0.0091893505,0.0045503783,0.030254392,0.00045926942],"about_ca_topic_score_codex":0.000006196001,"about_ca_topic_score_gemma":0.000015932788,"teacher_disagreement_score":0.6515679,"about_ca_system_score_codex":0.00015857357,"about_ca_system_score_gemma":0.0001522136,"threshold_uncertainty_score":0.9999129},"labels":[],"label_agreement":null},{"id":"W2025399263","doi":"10.1016/j.fct.2013.04.031","title":"Fas receptor-deficient lpr mice are protected against acetaminophen hepatotoxicity due to higher glutathione synthesis and enhanced detoxification of oxidant stress","year":2013,"lang":"en","type":"article","venue":"Food and Chemical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; McGill University; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; National Center for Research Resources; National Institute of General Medical Sciences","keywords":"Glutathione; GCLC; Acetaminophen; Chemistry; Nitrotyrosine; Oxidative stress; Peroxynitrite; Liver injury; Pharmacology; Reactive oxygen species; Nitric oxide synthase; Biochemistry; Biology; Enzyme","score_opus":0.0579571337891459,"score_gpt":0.3209334880040121,"score_spread":0.2629763542148662,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025399263","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947329,0.00020430026,0.00023571549,0.0015323755,0.00042461653,0.0018805852,0.00017032138,0.00012576209,0.0006933865],"genre_scores_gemma":[0.99676245,0.00012416662,0.0007791756,0.0008158468,0.00017253206,0.001158349,0.000022712838,0.000035924855,0.00012882391],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973092,0.0005142255,0.0006265777,0.0007387046,0.00020209323,0.00060917577],"domain_scores_gemma":[0.9982185,0.00048357566,0.00035829947,0.00026981966,0.00022249261,0.00044735207],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004117194,0.0003878968,0.0006759514,0.00017067176,0.00025980358,0.000033737786,0.00026177344,0.0009701105,0.000535382],"category_scores_gemma":[0.00038632864,0.00037590993,0.0000919325,0.00036833825,0.00035570972,0.00015163174,0.00021318485,0.00082717155,0.00011308172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002907524,0.00056941295,0.00046013828,0.00022478327,0.0001313102,0.000003895724,0.0005537976,0.000023200526,0.9763013,0.00023289393,0.00021045453,0.02099807],"study_design_scores_gemma":[0.0008511701,0.00041924504,0.004446922,0.00007853619,0.000076600976,0.000019898636,0.00025606478,0.00033053634,0.99128044,0.00037593872,0.001455207,0.00040941502],"about_ca_topic_score_codex":0.000040502215,"about_ca_topic_score_gemma":0.000029243818,"teacher_disagreement_score":0.020588655,"about_ca_system_score_codex":0.00012718375,"about_ca_system_score_gemma":0.000048633316,"threshold_uncertainty_score":0.9998693},"labels":[],"label_agreement":null},{"id":"W2025812706","doi":"10.1016/j.intimp.2009.09.001","title":"Alterations in serum levels of inflammatory cytokines (TNF, IL-1alpha, IL-1beta and IL-1Ra) 20years after sulfur mustard exposure: Sardasht-Iran cohort study","year":2009,"lang":"en","type":"article","venue":"International Immunopharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":65,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Shahed University; Ministry of Health and Medical Education; U.S. Department of Veterans Affairs","keywords":"Sulfur mustard; Immunology; Medicine; Cohort; Tumor necrosis factor alpha; Inflammation; Internal medicine; Toxicity","score_opus":0.06380412167547722,"score_gpt":0.38643102408244495,"score_spread":0.32262690240696773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025812706","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904234,0.000330978,0.000041623367,0.0015799893,0.0035440202,0.001768971,0.0008015869,0.0000942546,0.0014151698],"genre_scores_gemma":[0.9959805,0.0002699772,0.0000870103,0.001874231,0.00042319685,0.0003548078,0.000039496615,0.000035572186,0.00093521946],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9962394,0.0010352465,0.0011286509,0.0006428206,0.00038736442,0.00056647847],"domain_scores_gemma":[0.9984812,0.0003598424,0.00038060406,0.00027405625,0.0003335794,0.0001707096],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015026651,0.0004354182,0.0006056618,0.0005866223,0.0002711919,0.0000668754,0.0005245823,0.0004817152,0.003214987],"category_scores_gemma":[0.00011134069,0.0004799052,0.00014694812,0.00034812777,0.00027133137,0.0005378335,0.00018346796,0.0013212789,0.000087358654],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027862266,0.002001375,0.39438042,0.000055667268,0.0011087593,0.00043929598,0.0035491742,0.001129982,0.5683646,0.00028992182,0.00062906346,0.025265492],"study_design_scores_gemma":[0.0059451987,0.0006989882,0.8866687,0.000032003063,0.00022087434,0.0000850719,0.00035598315,0.0009781382,0.087823294,0.0005430516,0.016152104,0.00049662485],"about_ca_topic_score_codex":0.00011583891,"about_ca_topic_score_gemma":0.00033554665,"teacher_disagreement_score":0.49228826,"about_ca_system_score_codex":0.00025485596,"about_ca_system_score_gemma":0.00014814021,"threshold_uncertainty_score":0.9997653},"labels":[],"label_agreement":null},{"id":"W2026428647","doi":"10.1016/j.toxlet.2015.04.002","title":"Cytochrome P450-derived versus mitochondrial oxidant stress in acetaminophen hepatotoxicity","year":2015,"lang":"en","type":"letter","venue":"Toxicology Letters","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; McGill University; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; National Center for Research Resources; National Institute of General Medical Sciences","keywords":"Acetaminophen; Cytochrome P450; Metabolite; Toxicity; Mechanism (biology); Mitochondrion; Oxidative stress; Relevance (law); Pharmacology; Chemistry; Medicine; Biochemistry; Enzyme; Internal medicine; Political science","score_opus":0.15793418095533782,"score_gpt":0.3934701429279674,"score_spread":0.23553596197262958,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026428647","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6706694,0.0002502009,0.000086417225,0.30689976,0.014664346,0.0033233475,0.00072192756,0.0005191249,0.002865501],"genre_scores_gemma":[0.18096273,0.00019369142,0.0005338466,0.7932628,0.019233214,0.0020895593,0.001620019,0.00042803754,0.0016761564],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.98807114,0.004553453,0.0016216179,0.0020793225,0.00092254585,0.00275192],"domain_scores_gemma":[0.99546677,0.0016085004,0.0009577696,0.0011774048,0.00022083752,0.0005687221],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"category_scores_codex":[0.0014990985,0.0016341662,0.0021258283,0.0012089533,0.0005131638,0.00011573512,0.0017509746,0.008013373,0.0017368082],"category_scores_gemma":[0.0005529061,0.0018079367,0.0005796518,0.0008332214,0.0011687742,0.00042957568,0.00057960383,0.015997224,0.0015709221],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018976264,0.00042040765,0.0003385067,0.00025282806,0.0005735568,0.0050487802,0.00081946875,0.0004544863,0.45668432,0.000020154004,0.5325259,0.0009639434],"study_design_scores_gemma":[0.01598716,0.0010174777,0.0009763724,0.00017055537,0.0006645329,0.00030023104,0.00012076468,0.00061732356,0.09978323,0.00029538444,0.87724525,0.0028217046],"about_ca_topic_score_codex":0.00038934773,"about_ca_topic_score_gemma":0.0006896563,"teacher_disagreement_score":0.48970667,"about_ca_system_score_codex":0.0023286946,"about_ca_system_score_gemma":0.00070576894,"threshold_uncertainty_score":0.9996406},"labels":[],"label_agreement":null},{"id":"W2026488328","doi":"10.1093/toxsci/kfq009","title":"Mechanisms of Immune-Mediated Liver Injury","year":2010,"lang":"en","type":"review","venue":"Toxicological Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":298,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Alcohol Abuse and Alcoholism; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research","keywords":"Liver injury; Immune system; Inflammation; Innate immune system; Immunology; Acquired immune system; Kupffer cell; Biology; Drug; Medicine; Pharmacology","score_opus":0.3373912329476006,"score_gpt":0.500962016139691,"score_spread":0.16357078319209045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026488328","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012757535,0.98120373,0.00012257673,0.00009940838,0.0035108586,0.0019576508,0.00023805689,0.00023215417,0.011359807],"genre_scores_gemma":[0.005313962,0.9928235,0.0005435771,0.00038232736,0.00020924862,0.00027075736,0.000033720647,0.000024335233,0.00039859652],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99522364,0.0015550603,0.0011835493,0.00079051114,0.00045434284,0.00079292327],"domain_scores_gemma":[0.9966661,0.0016460442,0.0009825135,0.00029907457,0.00009162539,0.0003146428],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.004006747,0.0005745516,0.0017951819,0.00035106752,0.000660586,0.000047040172,0.0014062133,0.0031266832,0.0048565823],"category_scores_gemma":[0.00080182735,0.0003934146,0.00068987155,0.0012595167,0.001662733,0.00017541049,0.00037419522,0.0033916603,0.0008210484],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022402262,0.00041922132,0.00000461833,0.0012457983,0.00006948366,0.000023897237,0.000043015574,0.0000019827983,0.005564299,0.008940073,0.00016431985,0.9835009],"study_design_scores_gemma":[0.00017866233,0.00064453395,0.000017279035,0.00046321994,0.00033386084,0.000047665613,0.000016336222,0.00009377634,0.0039014916,0.0030279313,0.9907661,0.00050911534],"about_ca_topic_score_codex":0.000031447948,"about_ca_topic_score_gemma":0.000017795464,"teacher_disagreement_score":0.9906018,"about_ca_system_score_codex":0.0001045695,"about_ca_system_score_gemma":0.00048463154,"threshold_uncertainty_score":0.9999569},"labels":[],"label_agreement":null},{"id":"W2026642938","doi":"10.1159/000243199","title":"Furosemide Increases Total Calcium in Kidney and Cytoplasmic Free Calcium in Blood Mononuclear Cells of Guinea Pigs","year":2009,"lang":"en","type":"article","venue":"Biology of the Neonate","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Calcium; Furosemide; Peripheral blood mononuclear cell; Guinea pig; Kidney; Medicine; Endocrinology; Internal medicine; Pharmacology; Immunology; Biology; Biochemistry; In vitro","score_opus":0.06044246794701703,"score_gpt":0.3551239610763499,"score_spread":0.2946814931293329,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026642938","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99643254,0.00041220352,0.000007117079,0.0011242828,0.00046567273,0.00042864194,0.00018970676,0.000021852755,0.0009179576],"genre_scores_gemma":[0.99839365,0.00020184625,0.000097481665,0.0010583048,0.000062368155,0.000012697096,0.0000075173557,0.000010662057,0.00015545146],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981287,0.0007002342,0.00047574617,0.00028035056,0.00006736555,0.00034760608],"domain_scores_gemma":[0.9991122,0.0002519185,0.00022471379,0.00026010693,0.000038007216,0.00011303805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006645009,0.00019617032,0.0003954774,0.00018619513,0.00007784947,0.000003379397,0.00035697978,0.0005398252,0.000069949805],"category_scores_gemma":[0.00026205613,0.00016351552,0.00008986314,0.00025433084,0.00034606626,0.000060557497,0.000167147,0.0006494225,0.0000054063635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005239221,0.00041669764,0.04801079,0.00005560117,0.00004533197,0.000012214829,0.0003423564,0.00024351694,0.94642603,0.0004195493,0.00031429547,0.00318968],"study_design_scores_gemma":[0.003482229,0.0003741462,0.065921485,0.00006981212,0.00007347691,0.00004931477,0.000045190885,0.0007808137,0.92155415,0.00530137,0.0021346207,0.00021336389],"about_ca_topic_score_codex":0.001305703,"about_ca_topic_score_gemma":0.00016047226,"teacher_disagreement_score":0.02487187,"about_ca_system_score_codex":0.0000363612,"about_ca_system_score_gemma":0.000082705184,"threshold_uncertainty_score":0.666797},"labels":[],"label_agreement":null},{"id":"W2027138344","doi":"10.1089/108076803762718105","title":"Hydrolysis of Bimatoprost (Lumigan) to its Free Acid by Ocular Tissue <i>In Vitro</i>","year":2003,"lang":"en","type":"article","venue":"Journal of Ocular Pharmacology and Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Bimatoprost; Ciliary body; Sclera; Cornea; Chemistry; Agonist; Prodrug; Hydrolysis; Receptor; In vitro; Pharmacology; Ophthalmology; Biochemistry; Ocular hypertension; Medicine; Intraocular pressure","score_opus":0.04990556788287313,"score_gpt":0.3827400223956901,"score_spread":0.33283445451281696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027138344","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9843158,0.010154213,0.0008052294,0.0017821332,0.0015619855,0.00060464634,0.00006778068,0.000018702962,0.00068950345],"genre_scores_gemma":[0.9912729,0.0025599175,0.0005749391,0.0052356026,0.0001382556,0.000023929122,0.0000041484604,0.000036016594,0.00015426367],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99675184,0.0012268096,0.0009306766,0.0002898741,0.0002803539,0.00052042794],"domain_scores_gemma":[0.99845344,0.00023497456,0.0005403006,0.00019335498,0.0002545214,0.0003234179],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002144885,0.00032901866,0.0007273532,0.00040438515,0.00019236619,0.000017899543,0.00041840994,0.00060150516,0.00033503142],"category_scores_gemma":[0.00008367174,0.0003159179,0.00018172049,0.00055653544,0.00018400858,0.00022699508,0.000072781215,0.0014355176,0.000022167966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009700305,0.00066608365,0.0014261421,0.0000804392,0.00066581095,0.00012984705,0.0008437615,0.00022260704,0.9857956,0.0002464192,0.00053719175,0.0084160445],"study_design_scores_gemma":[0.0033126785,0.0003875487,0.000098553835,0.000016631253,0.00044434075,0.00024330328,0.000081396574,0.00029355235,0.7808617,0.0006596069,0.21336953,0.00023118289],"about_ca_topic_score_codex":0.0000072800403,"about_ca_topic_score_gemma":0.0000050602534,"teacher_disagreement_score":0.21283235,"about_ca_system_score_codex":0.00008942413,"about_ca_system_score_gemma":0.00013405495,"threshold_uncertainty_score":0.9999293},"labels":[],"label_agreement":null},{"id":"W2029245543","doi":"10.3899/jrheum.120336","title":"Paracetamol for the Management of Pain in Inflammatory Arthritis: A Systematic Literature Review","year":2012,"lang":"en","type":"review","venue":"Journal of Rheumatology Supplement","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; Mount Sinai Hospital","funders":"Alberta Innovates; Arthritis Society; Canadian Rheumatology Association; Pfizer","keywords":"Medicine; Arthritis; Pain management; Intensive care medicine; Systematic review; Alternative medicine; Inflammatory arthritis; Physical therapy; MEDLINE; Internal medicine; Pathology","score_opus":0.11135498902871963,"score_gpt":0.43067369681701506,"score_spread":0.3193187077882954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029245543","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000018988203,0.9899109,0.00034465294,0.0005647598,0.0019607432,0.0070462883,0.000118422366,0.00000954444,0.000025729223],"genre_scores_gemma":[0.0001955617,0.99702936,0.00046047466,0.0002375769,0.000077040146,0.001860621,0.00004538693,0.00004087479,0.000053103264],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.99118084,0.003949831,0.0037676443,0.00023740545,0.00030946362,0.0005547995],"domain_scores_gemma":[0.99316853,0.0021392317,0.0039393916,0.00038565038,0.00022200627,0.00014516056],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.014962551,0.0005047804,0.003415838,0.00041520072,0.00014297002,0.000020890717,0.00071728445,0.00072511105,0.0002682982],"category_scores_gemma":[0.0001831884,0.00032489776,0.0010132305,0.00040989314,0.000111057256,0.00014343816,0.00011215308,0.00184752,0.000016996742],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048257127,0.00019805714,0.00007309529,0.7002384,0.0021155195,0.00006627521,0.00024479293,0.0000039165775,3.1233347e-7,0.0013666583,0.0028530923,0.29279158],"study_design_scores_gemma":[0.0007797875,0.000118523865,0.0000011297321,0.38225216,0.00289412,0.0013453452,0.00009597467,0.000014417603,0.000003620584,0.00006880223,0.6122514,0.00017471552],"about_ca_topic_score_codex":0.0000025666,"about_ca_topic_score_gemma":0.000016388105,"teacher_disagreement_score":0.6093983,"about_ca_system_score_codex":0.00022008803,"about_ca_system_score_gemma":0.00020136789,"threshold_uncertainty_score":0.9999203},"labels":[],"label_agreement":null},{"id":"W2029513985","doi":"10.1159/000187893","title":"Immunochemical Study of Epidermal Growth Factor in Rats with Mercuric Chloride-Induced Acute Renal Failure","year":2008,"lang":"en","type":"article","venue":"˜The œNephron journals/Nephron journals","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Epidermal growth factor; Endocrinology; Internal medicine; Creatinine; Medicine; Kidney; Radioimmunoassay; Urinary system; Blood urea nitrogen; Saline; Excretion; Urine; Receptor","score_opus":0.12856489555038694,"score_gpt":0.39720643323229343,"score_spread":0.26864153768190646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029513985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932646,0.0012281607,0.0002257075,0.0022986273,0.0008153253,0.0016867465,0.00004687095,0.00008573209,0.0003481968],"genre_scores_gemma":[0.9956742,0.0015764022,0.00012439353,0.0011158073,0.0010393205,0.00013820888,0.000007596257,0.00010637265,0.00021768494],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9913091,0.002941917,0.0022978066,0.00073157565,0.001284306,0.0014353157],"domain_scores_gemma":[0.99546397,0.0007832213,0.001756575,0.0006473376,0.00065611216,0.0006927588],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0033311942,0.00087695394,0.0014191928,0.00087973976,0.0013900287,0.00011696265,0.0012319267,0.00086367276,0.0017964867],"category_scores_gemma":[0.00014593477,0.00063817017,0.00042654027,0.001629524,0.00041267567,0.0009823313,0.00021797017,0.0064905584,0.00010218067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0043715746,0.002983812,0.034309026,0.00006284087,0.0022744988,0.0018405943,0.012201889,0.0007659886,0.9329804,0.000022920733,0.0018775191,0.0063089407],"study_design_scores_gemma":[0.02040427,0.0043596616,0.12124598,0.00059641094,0.0013251901,0.015628181,0.005335187,0.0010082102,0.81841964,0.00089633453,0.008651944,0.002128983],"about_ca_topic_score_codex":0.00022911248,"about_ca_topic_score_gemma":0.0004847671,"teacher_disagreement_score":0.114560746,"about_ca_system_score_codex":0.00047477454,"about_ca_system_score_gemma":0.00056997046,"threshold_uncertainty_score":0.99991},"labels":[],"label_agreement":null},{"id":"W2029584211","doi":"10.1002/cbf.934","title":"Differential inhibitory effects of carbon tetrachloride on the hepatic plasma membrane, mitochondrial and endoplasmic reticular calcium transport systems: implications to hepatotoxicity","year":2001,"lang":"en","type":"article","venue":"Cell Biochemistry and Function","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Medical Research Council","keywords":"Endoplasmic reticulum; Calcium; Chemistry; Reticular connective tissue; Endocrinology; Internal medicine; Mitochondrion; Biochemistry; Biology; Medicine; Anatomy","score_opus":0.033098633227899216,"score_gpt":0.28875101128419545,"score_spread":0.25565237805629626,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029584211","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953721,0.00015321904,0.00033735405,0.00023099504,0.0015676003,0.0010400241,0.00003488708,0.00005723931,0.0012065921],"genre_scores_gemma":[0.9985816,0.00014928452,0.0000066031353,0.000153377,0.00048212527,0.00026344275,0.000026707638,0.00001829587,0.00031859125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998611,0.00020110446,0.0003418221,0.00041942604,0.00015144606,0.00027522183],"domain_scores_gemma":[0.99891615,0.00042808388,0.00014680512,0.00024085696,0.00006172528,0.00020637512],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020183837,0.0002594173,0.00026807905,0.000073540315,0.00033691185,0.000018809122,0.00010110869,0.00046081367,0.000031988857],"category_scores_gemma":[0.00007010105,0.0002191175,0.00007687151,0.0001950342,0.00015775264,0.00004504812,0.000027906284,0.0006221795,0.0000053846975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00084401714,0.00022026894,0.00478774,0.00048610326,0.000065923276,0.000006910545,0.00020558474,0.00013057138,0.9923748,0.000062483006,0.00007541231,0.0007402287],"study_design_scores_gemma":[0.0010863537,0.0002584256,0.002430145,0.00007320182,0.00023285605,0.000033492106,0.00008481911,0.0017883738,0.99223137,0.000034546458,0.0015278293,0.00021859021],"about_ca_topic_score_codex":0.00008699639,"about_ca_topic_score_gemma":0.0000071088093,"teacher_disagreement_score":0.0032094836,"about_ca_system_score_codex":0.00006413971,"about_ca_system_score_gemma":0.000040720854,"threshold_uncertainty_score":0.89353526},"labels":[],"label_agreement":null},{"id":"W2029657547","doi":"10.3109/1547691x.2014.983660","title":"Immunization with amodiaquine-modified hepatic proteins prevents amodiaquine-induced liver injury","year":2014,"lang":"en","type":"article","venue":"Journal of Immunotoxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Ulster University","keywords":"Amodiaquine; Immune system; Adjuvant; Liver injury; Immunology; Medicine; Immunization; Immune tolerance; Metabolite; Pharmacology; Chloroquine; Internal medicine","score_opus":0.06848628626761297,"score_gpt":0.3766485346021144,"score_spread":0.30816224833450145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029657547","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.988611,0.00020630096,0.005351901,0.00053259905,0.0020885647,0.001376077,0.000011781834,0.000082035534,0.0017397371],"genre_scores_gemma":[0.99654883,0.00023638978,0.0009203054,0.0011726001,0.0006413512,0.00013308263,0.000013739607,0.00007004692,0.0002636677],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9947934,0.0024699946,0.0012390519,0.0003606308,0.0004233115,0.000713579],"domain_scores_gemma":[0.9966407,0.0005297799,0.0015214526,0.00044020877,0.00056382304,0.00030404943],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0027444693,0.00047053795,0.00086091703,0.0005796154,0.0004888524,0.000055199973,0.0007092586,0.00092217483,0.00054096367],"category_scores_gemma":[0.00054700486,0.00039699883,0.00025294538,0.0005750678,0.00026202272,0.0005922331,0.0001332674,0.0023616604,0.00010883883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0046650893,0.001652841,0.0041720266,0.00018640063,0.00072125776,0.00010359258,0.0011978144,0.0015096421,0.9149048,0.0020165117,0.00038312605,0.0684869],"study_design_scores_gemma":[0.011033791,0.013246064,0.015067407,0.0003125304,0.00069383974,0.001262539,0.00015216651,0.009878248,0.9125435,0.0024348279,0.032231763,0.0011433738],"about_ca_topic_score_codex":0.00007747673,"about_ca_topic_score_gemma":0.000051893843,"teacher_disagreement_score":0.067343526,"about_ca_system_score_codex":0.00045104278,"about_ca_system_score_gemma":0.00038199825,"threshold_uncertainty_score":0.9999399},"labels":[],"label_agreement":null},{"id":"W2029702897","doi":"10.1016/s1995-7645(11)60227-7","title":"Hepatoprotective effect of Solanum xanthocarpum fruit extract against CCl4 induced acute liver toxicity in experimental animals","year":2011,"lang":"en","type":"article","venue":"Asian Pacific Journal of Tropical Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal College of Physicians and Surgeons of Canada","funders":"","keywords":"Lipid peroxidation; Catalase; Antioxidant; Superoxide dismutase; Glutathione; Chemistry; Liver injury; Pharmacology; Bilirubin; Acute toxicity; Toxicity; Carbon tetrachloride; Biochemistry; Traditional medicine; Enzyme; Medicine; Internal medicine","score_opus":0.10286579083403628,"score_gpt":0.39327526254301287,"score_spread":0.2904094717089766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029702897","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9877984,0.00067005184,0.0004331065,0.00041425665,0.0014441056,0.00075948925,0.00001187466,0.000025021473,0.008443693],"genre_scores_gemma":[0.9987406,0.00021687934,0.00026041188,0.00017155884,0.0005251866,0.000030041274,0.0000020539799,0.000028098431,0.000025160682],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9960021,0.0015970411,0.0011472767,0.00031317436,0.0004325313,0.0005079008],"domain_scores_gemma":[0.99808127,0.0003816015,0.0007797464,0.00021362175,0.000151117,0.000392638],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0014757803,0.0003706175,0.0010503745,0.00045145792,0.00012671445,0.000006855395,0.0003757423,0.00060979766,0.0006914524],"category_scores_gemma":[0.0003713931,0.00027803832,0.0002515502,0.00039457768,0.00037998316,0.00023759979,0.00006293087,0.002313382,0.000022652284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006161615,0.00086134765,0.041812133,0.00010244523,0.00049399404,0.0012216175,0.008307387,0.0000018277011,0.89397997,0.00019571252,0.00013424769,0.046727695],"study_design_scores_gemma":[0.005951394,0.008819296,0.049623985,0.00027976453,0.00023661985,0.00041084673,0.0017115596,0.00017917938,0.93171245,0.00030403314,0.0004992819,0.00027160227],"about_ca_topic_score_codex":0.000058769416,"about_ca_topic_score_gemma":0.000017770039,"teacher_disagreement_score":0.04645609,"about_ca_system_score_codex":0.00023697516,"about_ca_system_score_gemma":0.00009520857,"threshold_uncertainty_score":0.9999883},"labels":[],"label_agreement":null},{"id":"W2033528452","doi":"10.3109/1061186x.2013.765443","title":"Therapeutic effect of liposomal-N-acetylcysteine against acetaminophen-induced hepatotoxicity","year":2013,"lang":"en","type":"article","venue":"Journal of drug targeting","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nucro Technics; NOSM University; Laurentian University; Lakehead University","funders":"","keywords":"Acetylcysteine; Acetaminophen; Pharmacology; Antidote; Glutathione; acetaminophen overdose; Toxicity; Antipyretic; Lipid peroxidation; Medicine; Liver injury; Chemistry; Analgesic; Antioxidant; Biochemistry; Internal medicine; Enzyme","score_opus":0.04784291609413409,"score_gpt":0.36251756557482545,"score_spread":0.31467464948069135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033528452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933145,0.0011866143,0.000121041376,0.0006258468,0.0021109397,0.0008408729,0.000007018701,0.000054193715,0.0017389435],"genre_scores_gemma":[0.99782336,0.00019624154,0.00034887847,0.0005389485,0.0008267546,0.000034556757,0.0000038990734,0.000046820045,0.0001805501],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99546546,0.0019282065,0.0013130597,0.0002590435,0.0004469624,0.0005872943],"domain_scores_gemma":[0.9964215,0.0010229886,0.0015479289,0.00021947331,0.00046235824,0.00032575658],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0037126122,0.00039148642,0.0008866633,0.00029975944,0.00032025558,0.000042661617,0.00048444435,0.0004399096,0.00055100716],"category_scores_gemma":[0.000507738,0.00031523776,0.0004491098,0.00041199042,0.000121785204,0.0005551854,0.00010084308,0.0019332296,0.00012556548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036703856,0.00024522707,0.020406686,0.00027056786,0.00037592574,0.000026713331,0.0011056717,0.00047761895,0.94254786,0.00002943904,0.0009758912,0.03317137],"study_design_scores_gemma":[0.003244708,0.00082151766,0.0024126128,0.00014065573,0.00020948726,0.000077921075,0.00029375625,0.003230308,0.9851564,0.000190412,0.0038890112,0.000333174],"about_ca_topic_score_codex":0.00007019865,"about_ca_topic_score_gemma":0.0000039423107,"teacher_disagreement_score":0.042608585,"about_ca_system_score_codex":0.00016230675,"about_ca_system_score_gemma":0.00012152126,"threshold_uncertainty_score":0.99992996},"labels":[],"label_agreement":null},{"id":"W2033843445","doi":"","title":"A Child With Acute Liver and Kidney Failure Ongoing Encephalopathy: Effectiveness of Plasmapheresis on Acetaminophen Overdose, A Case Report","year":2014,"lang":"en","type":"article","venue":"International Journal of Clinical Pediatrics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Plasmapheresis; Acetaminophen; Hepatic encephalopathy; Encephalopathy; acetaminophen overdose; Liver failure; Acute kidney injury; Analgesic; Toxicity; Intensive care medicine; Anesthesia; Internal medicine; Cirrhosis; Acetylcysteine; Immunology","score_opus":0.06664782823721495,"score_gpt":0.43152161361495756,"score_spread":0.3648737853777426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033843445","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931968,0.00006715546,0.0024148792,0.0005385179,0.0020410775,0.00021556315,0.000049941606,0.000014178804,0.0014618877],"genre_scores_gemma":[0.9963536,0.00047840673,0.00093839417,0.0005817895,0.0015792417,0.0000056562526,0.0000068814206,0.000017217966,0.00003880836],"study_design_codex":"observational","study_design_gemma":"case_report","domain_scores_codex":[0.99699175,0.001044423,0.0010491915,0.00025159397,0.0004887737,0.00017428437],"domain_scores_gemma":[0.9940464,0.0034826633,0.0013502516,0.00012597673,0.0006662695,0.0003284581],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004276073,0.00018443112,0.00048854563,0.00023307775,0.00011010618,0.000029476423,0.00026302514,0.00037594663,0.0000661978],"category_scores_gemma":[0.0031165837,0.00014762617,0.00019902387,0.00016815803,0.00016404565,0.00023728049,0.000077988916,0.0013994783,0.000006638443],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.029069435,0.0039784154,0.69260883,0.0006983128,0.0041550086,0.15058467,0.0012842581,0.003205425,0.0026235674,0.0038325812,0.00231673,0.105642766],"study_design_scores_gemma":[0.058229055,0.016957432,0.2509656,0.0020594143,0.0068428293,0.48481646,0.00047912388,0.010373884,0.0558223,0.0052272384,0.10569054,0.0025361413],"about_ca_topic_score_codex":0.000027979191,"about_ca_topic_score_gemma":0.000015428677,"teacher_disagreement_score":0.44164324,"about_ca_system_score_codex":0.000056326375,"about_ca_system_score_gemma":0.00023573598,"threshold_uncertainty_score":0.6080115},"labels":[],"label_agreement":null},{"id":"W2034332774","doi":"10.1016/s0140-6736(00)02342-4","title":"Prevention of paracetamol poisoning","year":2000,"lang":"en","type":"letter","venue":"The Lancet","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Medicine; Acetaminophen; Referral; Public health; Poison control; Occupational safety and health; Incidence (geometry); Injury prevention; Population; Environmental health; Medical emergency; Intensive care medicine; Emergency medicine; Anesthesia; Family medicine","score_opus":0.21643308810428835,"score_gpt":0.43902929376453237,"score_spread":0.22259620566024402,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034332774","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.068693526,0.001496416,0.00010327358,0.8463771,0.0032335054,0.0017311076,0.00032915035,0.00026870426,0.07776722],"genre_scores_gemma":[0.12664708,0.001662999,0.00016684,0.824246,0.0242073,0.00026540423,0.00036564795,0.0000902357,0.022348484],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975011,0.0011952646,0.00037529343,0.00026269944,0.0002031103,0.0004625758],"domain_scores_gemma":[0.99876326,0.00033738586,0.00035181106,0.00047125548,0.000041946918,0.00003431818],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009653852,0.00025369745,0.0006127316,0.000083459316,0.00023625683,0.00002021387,0.00057901436,0.0012799785,0.002238697],"category_scores_gemma":[0.000043188236,0.00019465148,0.0001935923,0.0001704067,0.00016365558,0.0000706835,0.000050679173,0.004607807,0.00037845667],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002146038,0.000048297647,0.00018325227,0.00025559595,0.00023179039,0.000032802614,0.0003907245,0.00014021194,0.0013829368,0.00008492141,0.9593725,0.037662357],"study_design_scores_gemma":[0.0007569782,0.00007185349,0.00019364171,0.00008977879,0.00020295949,0.000032867138,0.000009864453,0.00020931619,0.008732593,0.0028465497,0.9866427,0.0002108641],"about_ca_topic_score_codex":0.000048785656,"about_ca_topic_score_gemma":0.000010415629,"teacher_disagreement_score":0.057953555,"about_ca_system_score_codex":0.000049816226,"about_ca_system_score_gemma":0.000070887305,"threshold_uncertainty_score":0.9986734},"labels":[],"label_agreement":null},{"id":"W2035709322","doi":"10.1055/s-0029-1240007","title":"Immunoallergic Drug-Induced Liver Injury in Humans","year":2009,"lang":"en","type":"review","venue":"Seminars in Liver Disease","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Idiosyncrasy; Mechanism (biology); Drug; Immune system; Immunogen; Liver injury; Medicine; Immunology; Metabolite; Bioinformatics; Pharmacology; Antibody; Biology; Internal medicine","score_opus":0.13878843827856435,"score_gpt":0.44252763979996435,"score_spread":0.3037392015214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035709322","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008918994,0.9825044,0.0000010178068,0.00006831408,0.0017362032,0.0028956349,0.00022862127,0.00014625522,0.0035005133],"genre_scores_gemma":[0.011183299,0.98506933,0.00002972658,0.0005181428,0.0005070659,0.00069565827,0.00022595392,0.00010436263,0.0016664267],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9936033,0.002601163,0.0012465575,0.0011344318,0.00035150658,0.0010630602],"domain_scores_gemma":[0.99772274,0.0004278149,0.000495921,0.00072731683,0.00006143538,0.00056478963],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0015376814,0.0009996467,0.0017865355,0.00113573,0.0002752338,0.00005207497,0.0009425435,0.0014491464,0.001070024],"category_scores_gemma":[0.00014271779,0.0010479587,0.000723068,0.0010998585,0.00018593638,0.00032240013,0.00026046706,0.00435501,0.0009824276],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028040123,0.0011802814,0.00019680077,0.0057351156,0.00011468735,0.0016592557,0.00074072176,0.000015817895,0.000014783908,0.00026788888,0.0017105138,0.9880837],"study_design_scores_gemma":[0.0008796112,0.000106195694,0.0007341942,0.010592531,0.00074445416,0.000016795999,0.00003738584,0.00012361702,0.000033094115,0.00043417935,0.9851186,0.0011793376],"about_ca_topic_score_codex":0.00027101854,"about_ca_topic_score_gemma":0.00021752658,"teacher_disagreement_score":0.9869044,"about_ca_system_score_codex":0.0010207146,"about_ca_system_score_gemma":0.00071239553,"threshold_uncertainty_score":0.9998472},"labels":[],"label_agreement":null},{"id":"W2036297146","doi":"10.1038/sj.clpt.6100064","title":"Safety and Pharmacokinetics of Paracetamol Following Intravenous Administration of 5 g During the First 24 h with a 2-g Starting Dose","year":2007,"lang":"en","type":"article","venue":"Clinical Pharmacology & Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"ASTER","funders":"","keywords":"Pharmacokinetics; Cmin; Cmax; Medicine; Pharmacology; Analgesic; Anesthesia; Intravenous Infusions; Adverse effect","score_opus":0.12490080159705448,"score_gpt":0.45394046447457537,"score_spread":0.3290396628775209,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036297146","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917803,0.000744806,0.000836091,0.00285797,0.0020751595,0.0011182259,0.000030598872,0.0000663438,0.0004905137],"genre_scores_gemma":[0.99039215,0.0012875478,0.0003366832,0.0073617236,0.00046396366,0.000024568004,0.000006398705,0.000040424668,0.00008652867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996479,0.00074228394,0.0015027479,0.00042482454,0.0002604572,0.0005907343],"domain_scores_gemma":[0.9961542,0.0023539893,0.00085491355,0.00024346364,0.00018368031,0.00020976897],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0037710234,0.00033368682,0.00064182334,0.0001180184,0.0005214467,0.000012890299,0.0003458169,0.00054061995,0.000097470045],"category_scores_gemma":[0.00004821231,0.00025862938,0.00021439625,0.0003938064,0.0010251519,0.00012224469,0.00010890912,0.0017398172,0.0000061407445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.05712366,0.005376153,0.2346969,0.0010325039,0.0082108155,0.00045461406,0.0073827947,0.0023606233,0.5872905,0.0005526977,0.00035936202,0.095159374],"study_design_scores_gemma":[0.015914548,0.002970349,0.114248626,0.000104150015,0.004083892,0.00015420651,0.0007145,0.0042719687,0.7857227,0.00027034243,0.07079321,0.0007515161],"about_ca_topic_score_codex":0.00001112339,"about_ca_topic_score_gemma":0.00006889171,"teacher_disagreement_score":0.19843218,"about_ca_system_score_codex":0.00006459213,"about_ca_system_score_gemma":0.00015749219,"threshold_uncertainty_score":0.9999866},"labels":[],"label_agreement":null},{"id":"W2036443789","doi":"10.1016/s2221-1691(12)60075-6","title":"Evaluation of antihepatotoxic potential of Solanum xanthocarpum fruit extract against antitubercular drugs induced hepatopathy in experimental rodents","year":2012,"lang":"en","type":"article","venue":"Asian Pacific Journal of Tropical Biomedicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal College of Physicians and Surgeons of Canada","funders":"CSIR-National Botanical Research Institute; Department of Science and Technology, Ministry of Science and Technology, India","keywords":"Antioxidant; Pharmacology; Glutathione; Isoniazid; Lipid peroxidation; Superoxide dismutase; Chemistry; Toxicity; Liver injury; Catalase; Liver toxicity; Traditional medicine; Biochemistry; Medicine; Enzyme; Pathology; Tuberculosis","score_opus":0.09081769569641035,"score_gpt":0.4091285038073893,"score_spread":0.31831080811097895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036443789","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926526,0.0019048768,0.00023944897,0.0003713027,0.002918947,0.0005563392,0.000021012987,0.000011453913,0.001324031],"genre_scores_gemma":[0.99883425,0.00023396613,0.00013712094,0.000089104564,0.0006524176,0.000008008024,0.000014233658,0.00002328591,0.0000076006263],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9950038,0.0015444664,0.0014438097,0.00022270848,0.0012646125,0.00052060105],"domain_scores_gemma":[0.9979246,0.00009721392,0.0009784652,0.00022346749,0.00041798316,0.0003582318],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0041643833,0.00027962626,0.00077502284,0.00071950775,0.000090336645,0.000008430988,0.00029772348,0.00051210483,0.00029249862],"category_scores_gemma":[0.00024317324,0.00024112627,0.00026768367,0.0005628406,0.00027514237,0.00040079717,0.00005662967,0.001103461,0.000013172458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005311363,0.001868575,0.0972979,0.00007119193,0.0002365228,0.000049081307,0.0025716757,0.000035249213,0.86144817,0.0000408487,0.000072090705,0.03577753],"study_design_scores_gemma":[0.008061082,0.0011648565,0.10199258,0.00028137825,0.0005418371,0.00023909805,0.005011998,0.003241684,0.8783549,0.00017646441,0.0006329746,0.0003011596],"about_ca_topic_score_codex":0.000028372257,"about_ca_topic_score_gemma":0.000002423014,"teacher_disagreement_score":0.03547637,"about_ca_system_score_codex":0.00027818733,"about_ca_system_score_gemma":0.00022963597,"threshold_uncertainty_score":0.98328435},"labels":[],"label_agreement":null},{"id":"W2036783417","doi":"10.1016/j.taap.2008.07.020","title":"Organochlorines inhibit acetaminophen glucuronidation by redirecting UDP-glucuronic acid towards the d-glucuronate pathway","year":2008,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Health Canada; Centre Hospitalier de l’Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Health Canada","keywords":"Glucuronidation; Glucuronate; Chemistry; Microsome; Glucuronic acid; Acetaminophen; Glucuronosyltransferase; Biochemistry; Pharmacology; Glucuronide; Metabolism; Enzyme; Biology","score_opus":0.09858374509708404,"score_gpt":0.35115722236709795,"score_spread":0.2525734772700139,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036783417","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97246814,0.0018220806,0.00022552139,0.0054364325,0.0035699354,0.0017472944,0.000089200505,0.00047810556,0.014163297],"genre_scores_gemma":[0.9859533,0.0017933921,0.00012232276,0.008043787,0.0011193843,0.0008569811,0.00010151914,0.0000838364,0.0019254907],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99529016,0.0011670962,0.00084816496,0.0010737996,0.00029047127,0.0013303126],"domain_scores_gemma":[0.99790066,0.00070875284,0.0004928361,0.00034804907,0.0001370026,0.0004127129],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0016452025,0.00071117684,0.000753395,0.00022365514,0.0024915424,0.000037435628,0.0006490776,0.001246701,0.002317816],"category_scores_gemma":[0.000108228254,0.00061235146,0.00014552737,0.0006388741,0.001426528,0.00027687615,0.00043450345,0.002809822,0.00041521192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008465261,0.0004900054,0.0006482455,0.0000674927,0.0003518165,0.00005889046,0.0020292194,0.00015257613,0.92019737,0.0025831866,0.01342912,0.059145525],"study_design_scores_gemma":[0.003166685,0.00029318754,0.001304683,0.0000053534095,0.00021078937,0.00043220774,0.00020561244,0.00045767977,0.73989534,0.00065816427,0.2528078,0.0005625007],"about_ca_topic_score_codex":0.00004042478,"about_ca_topic_score_gemma":0.000030356405,"teacher_disagreement_score":0.23937869,"about_ca_system_score_codex":0.00024493464,"about_ca_system_score_gemma":0.00034997784,"threshold_uncertainty_score":0.9996328},"labels":[],"label_agreement":null},{"id":"W2037193718","doi":"10.1081/dmr-55227","title":"Oxidative Stress Mediated Idiosyncratic Drug Toxicity","year":2005,"lang":"en","type":"article","venue":"Drug Metabolism Reviews","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Oxidative stress; Pharmacology; Biochemistry; Inflammation; Toxicity; Glutathione peroxidase; Drug metabolism; Glutathione; Hepatocyte; Superoxide dismutase; Metabolism; Biology; Enzyme; Immunology","score_opus":0.10221587168909398,"score_gpt":0.4038505234028904,"score_spread":0.30163465171379644,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037193718","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88069254,0.07670149,0.00053578033,0.0070105037,0.004681431,0.0048292675,0.00040361966,0.00059595366,0.0245494],"genre_scores_gemma":[0.941179,0.036614247,0.0015187832,0.010596312,0.002697016,0.00082112517,0.00018088915,0.00009087412,0.0063017993],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99335825,0.0035583407,0.0011942876,0.00070811156,0.00035799196,0.00082298764],"domain_scores_gemma":[0.9976605,0.0005103821,0.0006074148,0.0005662911,0.0001556364,0.000499754],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.003868545,0.00060040574,0.0011920404,0.00023901356,0.0005712258,0.000061519946,0.00063364534,0.00039467885,0.0031240645],"category_scores_gemma":[0.0006974055,0.00051719975,0.00040126854,0.0007600529,0.00020733943,0.0006291684,0.00014927863,0.0018363218,0.0047522876],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030615178,0.0020366276,0.0013891853,0.00080469355,0.0005818085,0.00004048572,0.012314522,0.00040734047,0.24076657,0.004669632,0.083957694,0.6527253],"study_design_scores_gemma":[0.0009065314,0.000011182505,0.00036386657,0.00006624945,0.0002468799,0.000009576296,0.00010157477,0.0008992694,0.22979447,0.0002909701,0.76685166,0.00045777732],"about_ca_topic_score_codex":0.000072932926,"about_ca_topic_score_gemma":0.0003581957,"teacher_disagreement_score":0.68289393,"about_ca_system_score_codex":0.00013582179,"about_ca_system_score_gemma":0.00011125124,"threshold_uncertainty_score":0.99972796},"labels":[],"label_agreement":null},{"id":"W2038483422","doi":"10.1097/mjt.0b013e31827f9cbf","title":"Acetylcysteine for Acetaminophen Overdose in Patients Who Weigh &gt;100 kg","year":2013,"lang":"en","type":"letter","venue":"American Journal of Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Acetylcysteine; Acetaminophen; acetaminophen overdose; Emergency medicine; Pharmacology","score_opus":0.09355392012041579,"score_gpt":0.39245536891829147,"score_spread":0.29890144879787567,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038483422","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.71140885,0.002017054,0.00070446625,0.26812893,0.011801233,0.0037042643,0.00033292157,0.0000836812,0.0018185996],"genre_scores_gemma":[0.22332714,0.0016175144,0.0011458545,0.7633364,0.0064299437,0.00013989124,0.000115880604,0.00023410491,0.0036532297],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.995836,0.0011431943,0.0012739821,0.00038702518,0.00050206785,0.0008577221],"domain_scores_gemma":[0.99576014,0.0008433198,0.0022648745,0.00035914686,0.000586964,0.00018555467],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0009875123,0.000612072,0.0013345872,0.0005680384,0.00012825559,0.000045480607,0.00084192405,0.0012329577,0.00042706943],"category_scores_gemma":[0.00007524435,0.00055313244,0.0005017523,0.0003483668,0.0004239595,0.00027569517,0.00008752664,0.005406819,0.00006863919],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002481227,0.001133939,0.01176572,0.0004434808,0.0030257043,0.00013571083,0.002719555,0.0002586653,0.0023384183,0.00007019295,0.65050143,0.32512596],"study_design_scores_gemma":[0.0040954403,0.0025266735,0.0013731533,0.00014025094,0.0005175158,0.00003742168,0.00006965126,0.00048752982,0.0016028003,0.0005226654,0.9880368,0.00059009827],"about_ca_topic_score_codex":0.00006392699,"about_ca_topic_score_gemma":0.0000057609027,"teacher_disagreement_score":0.49520752,"about_ca_system_score_codex":0.00085623417,"about_ca_system_score_gemma":0.00033996368,"threshold_uncertainty_score":0.999692},"labels":[],"label_agreement":null},{"id":"W2039018611","doi":"10.1002/hep.26564","title":"Detection of anti-isoniazid and anti–cytochrome P450 antibodies in patients with isoniazid-induced liver failure","year":2013,"lang":"en","type":"article","venue":"Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":131,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research","keywords":"Isoniazid; Liver injury; Medicine; CYP2E1; Antibody; Immune system; Pharmacology; CYP3A4; Hepatitis; Hepatology; Drug; Immunology; Internal medicine; Cytochrome P450; Gastroenterology; Pathology; Metabolism","score_opus":0.04236578752037782,"score_gpt":0.3249978785162879,"score_spread":0.2826320909959101,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039018611","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99758035,0.0001297346,0.00007924894,0.00030501053,0.00033276298,0.0011718451,0.00002206716,0.000083246916,0.00029576162],"genre_scores_gemma":[0.99911904,0.00015013287,0.0001459927,0.00034738987,0.000056380017,0.00010665194,0.000013129824,0.0000319434,0.000029362142],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99774516,0.0005636556,0.00047993043,0.00048808075,0.00016123391,0.00056195515],"domain_scores_gemma":[0.99893934,0.00019734423,0.00027915038,0.00022673114,0.00021045802,0.0001469725],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031424392,0.0003233837,0.00062407483,0.0003808931,0.00022243599,0.000020257503,0.00016533256,0.00075091457,0.0003077206],"category_scores_gemma":[0.000071207294,0.0002941517,0.00006120423,0.00038692754,0.00030607334,0.00037185976,0.00009635268,0.0009140235,0.000118392665],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019298744,0.0004809469,0.74640167,0.00014000143,0.000097599936,0.000019009372,0.00061151356,0.000012517752,0.24114266,0.000112408314,0.00006352392,0.010725188],"study_design_scores_gemma":[0.0030456295,0.0006706542,0.8374601,0.00003879482,0.00007056417,0.000052206735,0.00009937281,0.0021090696,0.15439482,0.00015609614,0.0015304007,0.0003722833],"about_ca_topic_score_codex":0.00082635495,"about_ca_topic_score_gemma":0.0008411056,"teacher_disagreement_score":0.09105846,"about_ca_system_score_codex":0.0000758883,"about_ca_system_score_gemma":0.00006554116,"threshold_uncertainty_score":0.99995106},"labels":[],"label_agreement":null},{"id":"W2039265908","doi":"10.2165/00002018-200124070-00003","title":"Management of Paracetamol Overdose","year":2001,"lang":"en","type":"review","venue":"Drug Safety","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":67,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Medicine; Acetaminophen; Regimen; Ingestion; Acetylcysteine; Toxicity; Pharmacokinetics; Pharmacology; Intensive care medicine; Drug; Anesthesia; Internal medicine","score_opus":0.19929945640177288,"score_gpt":0.4813305071893962,"score_spread":0.2820310507876233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039265908","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00002835755,0.93143886,0.00009953841,0.00006275393,0.0019728374,0.0020217483,0.00027064368,0.00012156539,0.06398369],"genre_scores_gemma":[0.00015206185,0.9892873,0.00015071372,0.00012974761,0.00031557577,0.000241886,0.000199458,0.00006780292,0.009455417],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99637645,0.0011793864,0.0010965342,0.0005543246,0.00025789288,0.0005354217],"domain_scores_gemma":[0.9981443,0.00035823128,0.0007188957,0.000520867,0.00005835725,0.00019933707],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0014036122,0.0005699031,0.0016167122,0.00023091775,0.00025065467,0.000012718196,0.0005420024,0.0009262525,0.0018098861],"category_scores_gemma":[0.000017954602,0.0005248447,0.0007127768,0.0007102183,0.00014629462,0.00009830098,0.00021894036,0.0017193194,0.00086304033],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006995685,0.00026897664,0.0000068844984,0.016417088,0.0008378715,0.00013017116,0.000111481444,0.000023859799,0.0000012197736,0.0022125733,0.0011662642,0.9787536],"study_design_scores_gemma":[0.0006008375,0.000023360837,0.000009560909,0.0031252604,0.0017810044,0.000058633388,0.000037507583,0.000029536886,0.000056389108,0.00021398421,0.9935969,0.0004669929],"about_ca_topic_score_codex":0.000034826124,"about_ca_topic_score_gemma":0.0000074804393,"teacher_disagreement_score":0.9924307,"about_ca_system_score_codex":0.0002572479,"about_ca_system_score_gemma":0.00012253365,"threshold_uncertainty_score":0.9999149},"labels":[],"label_agreement":null},{"id":"W2041832372","doi":"10.1177/0091270010397730","title":"Estimation of Onset of Analgesia From Simulated Data","year":2011,"lang":"en","type":"letter","venue":"The Journal of Clinical Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Pharmacokinetics; Acetaminophen; Analgesic; Clinical trial; Covariate; Clinical pharmacology; Pain relief; Anesthesia; Pharmacology; Internal medicine; Statistics","score_opus":0.4859159350533638,"score_gpt":0.5559504315765739,"score_spread":0.07003449652321009,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041832372","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8497986,0.001564219,0.0010201627,0.122574985,0.021046923,0.0012168199,0.0018197342,0.0000416608,0.0009168738],"genre_scores_gemma":[0.8175978,0.002645275,0.0003828306,0.1716004,0.007188598,0.0000032644298,0.00033823325,0.00006164254,0.00018194997],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9863115,0.0084155705,0.004007552,0.00036128864,0.00046806692,0.00043602544],"domain_scores_gemma":[0.98057216,0.011320849,0.006623879,0.0007471824,0.0005511649,0.00018474208],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.009475679,0.0004128964,0.0019613865,0.00030752685,0.0001311874,0.000005995153,0.0026104385,0.0027982309,0.0034807012],"category_scores_gemma":[0.0012152235,0.0003028181,0.0004932785,0.0003159512,0.0010582707,0.00024425905,0.00042758312,0.010563719,0.00006544643],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0056062615,0.00083282,0.0009814353,0.00022524728,0.0037897867,0.0002738008,0.00038293272,0.003932776,0.0044714897,0.0000046749687,0.95502704,0.02447172],"study_design_scores_gemma":[0.009621296,0.0023036078,0.003236343,0.00026988215,0.01276019,0.00029713128,0.000052662886,0.045520645,0.061398305,0.0051061176,0.85872144,0.00071237015],"about_ca_topic_score_codex":0.00021953716,"about_ca_topic_score_gemma":0.000010475964,"teacher_disagreement_score":0.0963056,"about_ca_system_score_codex":0.00004939851,"about_ca_system_score_gemma":0.0006556149,"threshold_uncertainty_score":0.9999424},"labels":[],"label_agreement":null},{"id":"W2042796837","doi":"10.1002/pds.1014","title":"Risks of herbal medicinal products","year":2004,"lang":"en","type":"review","venue":"Pharmacoepidemiology and Drug Safety","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":129,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Victoria Park","funders":"","keywords":"Narrative review; Medicine; Popularity; Medical prescription; Risk analysis (engineering); Consumer safety; Traditional medicine; Pharmacology; Intensive care medicine","score_opus":0.424165026761114,"score_gpt":0.5492571988538425,"score_spread":0.1250921720927285,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042796837","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00014717327,0.988691,0.0001676024,0.00115216,0.003818369,0.0020646912,0.0003865938,0.00016923434,0.003403181],"genre_scores_gemma":[0.0021352805,0.9942618,0.00040609154,0.0009122219,0.0012267196,0.00025048826,0.00024407974,0.00008120385,0.0004821327],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.98775804,0.007539216,0.0023194442,0.0011754239,0.00021933587,0.0009885303],"domain_scores_gemma":[0.99282724,0.0044811703,0.0015790429,0.00045018585,0.00017287392,0.00048947573],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00968249,0.0009894753,0.003793155,0.00039976824,0.00052342203,0.0000072930006,0.0005929128,0.0018453847,0.0006961789],"category_scores_gemma":[0.0015762268,0.0008254811,0.00058167306,0.00061441865,0.001131028,0.00017083979,0.00029140062,0.004705632,0.00019404273],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003398095,0.00029813006,0.0001544798,0.027786316,0.00094450027,0.00005320489,0.0003276243,0.0000524194,0.000040251052,0.0031083734,0.0026046936,0.9642902],"study_design_scores_gemma":[0.0015379974,0.00010125635,0.000038534097,0.0032070163,0.0027130453,0.00038243263,0.000026002006,0.000063617845,0.00029115583,0.0011734808,0.98977286,0.00069260545],"about_ca_topic_score_codex":0.0003014867,"about_ca_topic_score_gemma":0.00001685269,"teacher_disagreement_score":0.98716813,"about_ca_system_score_codex":0.0002734248,"about_ca_system_score_gemma":0.0008462032,"threshold_uncertainty_score":0.99945045},"labels":[],"label_agreement":null},{"id":"W2043192457","doi":"10.1002/1099-1573(200011)14:7<568::aid-ptr663>3.0.co;2-q","title":"Effect of Withania somnifera glycowithanolides on iron-induced hepatotoxicity in rats","year":2000,"lang":"en","type":"article","venue":"Phytotherapy Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Drug Research and Development","funders":"","keywords":"Withania somnifera; Hepatoprotection; Lipid peroxidation; Antioxidant; Pharmacology; Lactate dehydrogenase; Chemistry; Aché; Biochemistry; Acetylcholinesterase; Traditional medicine; Enzyme; Medicine; Glutathione; Pathology","score_opus":0.20055618471000702,"score_gpt":0.5194980612436825,"score_spread":0.31894187653367545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043192457","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9816238,0.00018432338,0.0000023331795,0.00036332032,0.00030226304,0.0018728047,0.00002963652,0.00008547192,0.01553599],"genre_scores_gemma":[0.9969961,0.0005965192,0.000015822907,0.00038794315,0.0003009286,0.00043235905,0.00000782868,0.000058784604,0.0012036819],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99252737,0.004668482,0.0005109208,0.00061149657,0.00068454864,0.0009971771],"domain_scores_gemma":[0.9974949,0.0015764558,0.00009715752,0.00046404832,0.00012048004,0.00024700293],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.005770006,0.00035524016,0.00057507335,0.00057005434,0.00035585806,0.000034081193,0.00049231405,0.0005958915,0.0038585595],"category_scores_gemma":[0.00013616464,0.0003137107,0.00015364378,0.001138749,0.00029456723,0.00018745064,0.00004032792,0.0025768012,0.0006006755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011449164,0.0010085714,0.018312754,0.00022139549,0.00008756511,0.000061022834,0.0012962951,0.0003816443,0.7180121,0.00026899923,0.00026162338,0.24863888],"study_design_scores_gemma":[0.0035875817,0.0040098745,0.0036598206,0.00010534818,0.0000105854615,0.000011314469,0.000023734643,0.0012996909,0.9809762,0.0006780897,0.0053466926,0.00029101854],"about_ca_topic_score_codex":0.0005010176,"about_ca_topic_score_gemma":0.0002024015,"teacher_disagreement_score":0.26296416,"about_ca_system_score_codex":0.00026573704,"about_ca_system_score_gemma":0.00014481838,"threshold_uncertainty_score":0.9999315},"labels":[],"label_agreement":null},{"id":"W2044069693","doi":"10.3821/1913-701x-141.sp2.s21","title":"Questioning the Role of Routine Liver Enzyme Monitoring in Statin Therapy","year":2008,"lang":"en","type":"article","venue":"Canadian Pharmacists Journal / Revue des Pharmaciens du Canada","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Vancouver Coastal Health","funders":"","keywords":"Liver enzyme; Statin; Medicine; Intensive care medicine; Internal medicine","score_opus":0.13558057465449594,"score_gpt":0.35467351455903545,"score_spread":0.2190929399045395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044069693","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908093,0.004497583,0.000036083948,0.00011598802,0.002398701,0.0005151288,0.00014487588,0.000026834045,0.0014554646],"genre_scores_gemma":[0.98078656,0.016846636,0.00009706967,0.000891507,0.0010274198,0.000045872042,0.000009504519,0.000046054545,0.0002493541],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99656147,0.0009449567,0.00077669864,0.00033172933,0.00037380942,0.0010113191],"domain_scores_gemma":[0.9976157,0.00035094327,0.00039350454,0.00020191816,0.00039994638,0.0010379888],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.001584351,0.00036519844,0.00039320908,0.00040794906,0.0015170823,0.00004978,0.00065795804,0.00017823248,0.00075527333],"category_scores_gemma":[0.00019100342,0.00033987887,0.00014133487,0.00080201484,0.00035968047,0.000372544,0.000041098527,0.002185664,0.000013703399],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010526377,0.00039017788,0.1984099,0.0001770776,0.00059777056,0.043042745,0.025224796,0.027428487,0.12875345,0.00033402373,0.0030854065,0.5715035],"study_design_scores_gemma":[0.0065616807,0.0001689803,0.0028608004,0.00007735334,0.00014134056,0.26062012,0.00021319996,0.024166198,0.535478,0.00045102503,0.16802299,0.0012383],"about_ca_topic_score_codex":0.07172991,"about_ca_topic_score_gemma":0.049700085,"teacher_disagreement_score":0.57026523,"about_ca_system_score_codex":0.001683659,"about_ca_system_score_gemma":0.0027286296,"threshold_uncertainty_score":0.99990535},"labels":[],"label_agreement":null},{"id":"W2046179960","doi":"10.1002/cbf.1259","title":"The effects of dietary flaxseed on the Fischer 344 rat. III. Protection against CCl<sub>4</sub>‐induced liver injury","year":2005,"lang":"en","type":"article","venue":"Cell Biochemistry and Function","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Saskatchewan Flax Development Commission","keywords":"Carbon tetrachloride; Endocrinology; Internal medicine; Liver injury; Body weight; CCL4; Chemistry; Alanine aminotransferase; Medicine","score_opus":0.040422983303537253,"score_gpt":0.29109272904502764,"score_spread":0.25066974574149037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046179960","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99340427,0.00049573084,0.00005442806,0.000682486,0.0012791046,0.0008588319,0.000006620223,0.00007113423,0.0031474044],"genre_scores_gemma":[0.9966817,0.0008432607,0.0000037400034,0.0008777874,0.00069227605,0.00021133653,0.000017092498,0.0000189497,0.000653853],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859303,0.0003460297,0.00028140223,0.00033191245,0.00015733746,0.0002902625],"domain_scores_gemma":[0.99893755,0.00040609838,0.00021634343,0.00025926996,0.000077022254,0.000103699334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00066670665,0.00025076937,0.0001682367,0.00003929465,0.0008963403,0.000030675295,0.00013568324,0.0005485208,0.000033856686],"category_scores_gemma":[0.00011982548,0.00017380975,0.00011209662,0.0001938829,0.00018324547,0.00010056771,0.00005267801,0.0011216766,0.000055214692],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009695139,0.00018822367,0.000031051524,0.00017225576,0.00006631937,0.0000015399141,0.00015656475,0.000026976988,0.8692035,0.000020373434,0.001499788,0.12766387],"study_design_scores_gemma":[0.0007869052,0.00033712803,0.00034070047,0.00004216029,0.000100543366,0.0000039671795,0.00008965598,0.0013069746,0.9802903,0.00006530413,0.016441647,0.00019474741],"about_ca_topic_score_codex":0.000008634613,"about_ca_topic_score_gemma":0.0000068749955,"teacher_disagreement_score":0.12746911,"about_ca_system_score_codex":0.00007593145,"about_ca_system_score_gemma":0.000045706656,"threshold_uncertainty_score":0.7087756},"labels":[],"label_agreement":null},{"id":"W2046767608","doi":"10.1111/j.1542-4758.2009.00370.x","title":"Intraoperative dialysis during liver transplantation with citrate dialysate","year":2009,"lang":"en","type":"article","venue":"Hemodialysis International","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Dialysis; Fulminant hepatic failure; Hemodialysis; Liver transplantation; Transplantation; Fulminant; Surgery; Heparin; Anticoagulant; Anesthesia","score_opus":0.05588611827305684,"score_gpt":0.3600570205465757,"score_spread":0.30417090227351884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046767608","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97244525,0.000040292125,0.0036558134,0.0011751823,0.0007654349,0.00032952317,0.000068754634,0.00015576568,0.02136401],"genre_scores_gemma":[0.99573994,0.00067912746,0.0005912186,0.0011286811,0.00080569286,0.000069292626,0.0001670795,0.000017471732,0.00080147706],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981662,0.00035554392,0.00037374825,0.00043118172,0.0003444134,0.00032893286],"domain_scores_gemma":[0.9991791,0.0001196497,0.00017386064,0.00015863271,0.00021382002,0.00015494012],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004315132,0.0002642099,0.00028158003,0.00032786443,0.00037872026,0.00008105971,0.00027186648,0.00025520692,0.0019127603],"category_scores_gemma":[0.000038529306,0.0002390224,0.0001660624,0.0003887601,0.000094048504,0.00046054166,0.00001680057,0.0006329105,0.00019733756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008924979,0.0022274444,0.031068813,0.00014267756,0.004032885,0.0010800536,0.02206449,0.03336598,0.6804692,0.009121022,0.0005067788,0.20699568],"study_design_scores_gemma":[0.006390804,0.0003126849,0.07231643,0.000058952457,0.0011465487,0.0002979621,0.00020387946,0.024108069,0.88308185,0.0015190392,0.009508187,0.0010555745],"about_ca_topic_score_codex":0.000052136733,"about_ca_topic_score_gemma":0.00014275363,"teacher_disagreement_score":0.2059401,"about_ca_system_score_codex":0.00018481615,"about_ca_system_score_gemma":0.00005591267,"threshold_uncertainty_score":0.99899966},"labels":[],"label_agreement":null},{"id":"W2047416003","doi":"10.1002/lt.21021","title":"Acute liver failure induced by green tea extracts: Case report and review of the literature","year":2006,"lang":"en","type":"article","venue":"Liver Transplantation","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":170,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen Elizabeth II Health Sciences Centre; Dalhousie University","funders":"","keywords":"Medicine; Green tea; Health benefits; Traditional medicine; Intensive care medicine; Food science","score_opus":0.0409026406964498,"score_gpt":0.3478432230222304,"score_spread":0.30694058232578064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047416003","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9875617,0.008521335,0.0001488436,0.000959339,0.0003275728,0.00088405394,0.00046082734,0.000047424277,0.0010889081],"genre_scores_gemma":[0.9807401,0.017104402,0.00010240984,0.0010873866,0.00012030325,0.000045221637,0.000260295,0.000013980555,0.0005259413],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986727,0.0003963355,0.0003627802,0.00024627108,0.00014741837,0.00017449145],"domain_scores_gemma":[0.99934345,0.00010747284,0.00023825016,0.00015351351,0.00009891103,0.00005840724],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041546862,0.00017303143,0.00019187503,0.000050957373,0.00023432725,0.00001587231,0.0000971015,0.00035680007,0.000107365515],"category_scores_gemma":[0.0000109492785,0.00013610156,0.0000839649,0.00025376937,0.00007229227,0.0002631027,0.000011957159,0.00067457405,0.000007293547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007887649,0.0007837969,0.0039804177,0.028366312,0.00062113,0.06511089,0.0100988895,0.000021897704,0.8405552,0.0012338415,0.010530743,0.037908107],"study_design_scores_gemma":[0.003663613,0.00024919357,0.011661397,0.0054325643,0.0033774553,0.18133895,0.00012115616,0.00046993504,0.7369092,0.00056663976,0.05526229,0.0009475912],"about_ca_topic_score_codex":0.0005901819,"about_ca_topic_score_gemma":0.00032664422,"teacher_disagreement_score":0.11622806,"about_ca_system_score_codex":0.000028159542,"about_ca_system_score_gemma":0.000033812816,"threshold_uncertainty_score":0.5550061},"labels":[],"label_agreement":null},{"id":"W2048839381","doi":"10.1186/1472-6963-7-159","title":"Validation of ICD-9-CM/ICD-10 coding algorithms for the identification of patients with acetaminophen overdose and hepatotoxicity using administrative data","year":2007,"lang":"en","type":"article","venue":"BMC Health Services Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Fondation pour la Recherche Médicale; Canadian Liver Foundation; Canadian Association of Gastroenterology","keywords":"Medicine; Acetaminophen; acetaminophen overdose; Algorithm; Hepatic encephalopathy; Drug overdose; Confidence interval; Internal medicine; Emergency medicine; Poison control; Cirrhosis; Anesthesia; Acetylcysteine","score_opus":0.4235153371062626,"score_gpt":0.5633190918219302,"score_spread":0.13980375471566758,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048839381","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9852431,0.00023665768,0.010515983,0.00008484925,0.0001810196,0.0029685555,0.00070879323,0.000016979042,0.000044059372],"genre_scores_gemma":[0.99777836,0.00013892903,0.0014727265,0.000101982594,0.00011580837,0.000056903915,0.00027601223,0.000019523022,0.000039769813],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967327,0.0009674328,0.0007879474,0.0004315427,0.00056223036,0.00051811594],"domain_scores_gemma":[0.99576026,0.0021178825,0.00065734,0.0004837843,0.0007995907,0.00018111258],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.010820962,0.00015553215,0.00028707882,0.00021370717,0.00083410804,0.000035909758,0.00050410355,0.00023061337,0.000042290543],"category_scores_gemma":[0.00013836837,0.00012373703,0.00003144428,0.00058374554,0.0002785493,0.00039243672,0.00022419375,0.000554638,0.0000027357169],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015155281,0.0033158779,0.7166807,0.018729435,0.0007459267,0.0000040958244,0.025421815,0.0014525309,0.12247338,0.0015475514,0.00009278449,0.09438063],"study_design_scores_gemma":[0.0041632056,0.0012329619,0.3110224,0.00028387702,0.00012905977,0.000005078073,0.0049328622,0.19970869,0.47551304,0.0003610017,0.0023227222,0.00032511342],"about_ca_topic_score_codex":0.0005528297,"about_ca_topic_score_gemma":0.0003960719,"teacher_disagreement_score":0.4056583,"about_ca_system_score_codex":0.00015309674,"about_ca_system_score_gemma":0.00044092283,"threshold_uncertainty_score":0.6415369},"labels":[],"label_agreement":null},{"id":"W2049813439","doi":"10.1080/15563650701447020","title":"Are recommended doses of acetaminophen hepatotoxic for recently abstinent alcoholics? A randomized trial","year":2008,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Medicine; Acetaminophen; Placebo; Abstinence; Internal medicine; Randomized controlled trial; Liver function tests; Liver function; Subclinical infection; Gastroenterology; Anesthesia; Psychiatry; Pathology","score_opus":0.5083173333724131,"score_gpt":0.5372928709114341,"score_spread":0.028975537539020935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049813439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97736543,0.0002542181,0.0006162253,0.0033530353,0.008861297,0.006552864,0.00015101583,0.00019057881,0.0026553348],"genre_scores_gemma":[0.98699135,0.0017234798,0.0012490078,0.004924328,0.001751644,0.00184835,0.00005378904,0.000060541763,0.0013975411],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.991088,0.0043749763,0.0026431915,0.00082275696,0.00023281875,0.00083825696],"domain_scores_gemma":[0.9854482,0.011268929,0.0019820712,0.00049952156,0.00034846834,0.00045285313],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.006774283,0.00046375458,0.0023924713,0.0002367996,0.00049687386,0.0000111530235,0.0005613738,0.0018680581,0.0009672541],"category_scores_gemma":[0.009538812,0.00042404278,0.0012181188,0.00033757053,0.0012737218,0.00012580726,0.00017898376,0.0016730292,0.000136502],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9507616,0.0046369797,0.006054541,0.0001670994,0.0011344549,0.000060575043,0.00043929453,0.00009182936,0.0063154786,0.0013947469,0.014013621,0.014929769],"study_design_scores_gemma":[0.82325166,0.002063376,0.0014322407,0.000037698326,0.0005077091,0.000073300354,0.000069852926,0.002112046,0.027326263,0.0038489762,0.13870792,0.000568934],"about_ca_topic_score_codex":0.000019116982,"about_ca_topic_score_gemma":0.000040394458,"teacher_disagreement_score":0.12750994,"about_ca_system_score_codex":0.00012247168,"about_ca_system_score_gemma":0.00027337944,"threshold_uncertainty_score":0.999946},"labels":[],"label_agreement":null},{"id":"W2050140514","doi":"10.1038/sj.bjp.0705781","title":"Acetaminophen hepatotoxicity: NO to the rescue","year":2004,"lang":"en","type":"letter","venue":"British Journal of Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Acetaminophen; Ursodeoxycholic acid; Liver injury; Medicine; Analgesic; Pharmacology; Toxicity; acetaminophen overdose; Nitric oxide; Chemistry; Internal medicine; Acetylcysteine; Biochemistry; Antioxidant","score_opus":0.08496577158730127,"score_gpt":0.3899318719742867,"score_spread":0.3049661003869854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050140514","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07726786,0.0042887228,0.00039214306,0.86237156,0.047149822,0.0031884946,0.0006735001,0.00017203335,0.004495845],"genre_scores_gemma":[0.05683317,0.0027328646,0.00030508448,0.89301157,0.041401945,0.00020017002,0.0000612774,0.0001733682,0.0052805273],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9919832,0.0033575254,0.001722983,0.00068705843,0.00081089546,0.001438378],"domain_scores_gemma":[0.99613166,0.0008336123,0.0011968595,0.00027621718,0.0011004762,0.00046117397],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0035060362,0.0007307033,0.0013473477,0.00054552965,0.0009410209,0.00017548834,0.0021274306,0.0030557876,0.0044983756],"category_scores_gemma":[0.00049213244,0.0007106837,0.0007818379,0.00061851443,0.00044740504,0.00031396185,0.00036928666,0.01856753,0.0018737636],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042019456,0.00026874,0.000023722674,0.00021528576,0.0009975643,0.011941826,0.0003129586,0.0010674588,0.020539567,0.00001008053,0.9423977,0.021804903],"study_design_scores_gemma":[0.0029033204,0.0006570337,0.0000737545,0.00025712908,0.00089192943,0.01294444,0.000024739797,0.00008005706,0.030000377,0.00035039286,0.95113057,0.0006862703],"about_ca_topic_score_codex":0.00035398582,"about_ca_topic_score_gemma":0.00013757308,"teacher_disagreement_score":0.030640021,"about_ca_system_score_codex":0.0008871083,"about_ca_system_score_gemma":0.0010851233,"threshold_uncertainty_score":0.9995344},"labels":[],"label_agreement":null},{"id":"W2051225469","doi":"10.1007/s11010-013-1864-7","title":"Lack of liver injury in Wistar rats treated with the combination of isoniazid and rifampicin","year":2013,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Liver injury; Isoniazid; Rifampicin; Medicine; Pharmacology; Animal model; Internal medicine; Pathology; Tuberculosis","score_opus":0.03501103658793104,"score_gpt":0.32165275080525435,"score_spread":0.2866417142173233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051225469","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99788135,0.000710316,0.00009975646,0.00027766405,0.000014955655,0.00031280846,0.000010380214,0.000008116559,0.0006846324],"genre_scores_gemma":[0.9995764,0.000050345738,0.00003123786,0.00017432218,0.000008617418,0.00002660626,0.000015703454,0.000008446828,0.00010835327],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929804,0.00015303397,0.00016400387,0.00016320297,0.00007895016,0.00014275253],"domain_scores_gemma":[0.9996249,0.00003671365,0.00010142512,0.000117909265,0.00006229942,0.000056740435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022421572,0.000116238785,0.00015543283,0.00003706932,0.00005188565,0.000007813233,0.000069491594,0.00020992619,0.000051495914],"category_scores_gemma":[0.000013024245,0.00008977104,0.000025738256,0.0001340084,0.00023751054,0.000033746022,0.00003230665,0.00027869781,0.0000018256128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001051641,0.00015569797,0.0064043775,0.00015818614,0.00003876003,0.0000083979385,0.00015719258,0.0000062780705,0.99049336,0.00013412269,0.000046163354,0.0022923185],"study_design_scores_gemma":[0.00067831646,0.00013938766,0.0013579559,0.000026317994,0.000043701835,0.000006212877,0.00011054032,0.00048744894,0.9967097,0.00015199446,0.00018971461,0.00009867555],"about_ca_topic_score_codex":0.00022190597,"about_ca_topic_score_gemma":0.000005273892,"teacher_disagreement_score":0.0062163924,"about_ca_system_score_codex":0.000014815268,"about_ca_system_score_gemma":0.000021891003,"threshold_uncertainty_score":0.36607566},"labels":[],"label_agreement":null},{"id":"W2054367254","doi":"10.1097/ccm.0b013e31829791a2","title":"Character and Temporal Evolution of Apoptosis in Acetaminophen-Induced Acute Liver Failure*","year":2013,"lang":"en","type":"article","venue":"Critical Care Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Medical Research Council; National Institute for Health and Care Research; Wellcome Trust; Howard Hughes Medical Institute","keywords":"Medicine; Acetaminophen; Internal medicine; Liver transplantation; Gastroenterology; Liver failure; Liver disease; Chronic liver disease; Transplantation; Anesthesia; Cirrhosis","score_opus":0.08103866786733124,"score_gpt":0.39665946401556174,"score_spread":0.31562079614823046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054367254","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99078965,0.0006279039,0.00015948618,0.005328456,0.00077988056,0.0006012002,0.000017260303,0.000043652082,0.0016524842],"genre_scores_gemma":[0.99844617,0.000058602353,0.00013489406,0.00080066384,0.00032862343,0.000116245705,0.00002017755,0.000015419786,0.00007920057],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983915,0.00035676433,0.00040000127,0.00030068387,0.00018711675,0.00036391176],"domain_scores_gemma":[0.9989431,0.00034991026,0.00006335015,0.00015093353,0.00025612398,0.00023658082],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000383636,0.00019626407,0.00038649692,0.00020788818,0.00011118221,0.000008519819,0.00011872571,0.00044958468,0.001121405],"category_scores_gemma":[0.00034979344,0.00016885869,0.000046610578,0.00024719935,0.00044738426,0.00024398426,0.00006268775,0.0008411178,0.00006844365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002473386,0.0003000177,0.06721638,0.00096979854,0.000105184,0.00004377771,0.0070453715,0.0000012602532,0.862447,0.0075142197,0.0011260944,0.05298351],"study_design_scores_gemma":[0.012126973,0.0035838333,0.25811398,0.00078915246,0.0012694732,0.00019144485,0.017945532,0.004188185,0.6736972,0.009272559,0.017320385,0.0015012927],"about_ca_topic_score_codex":0.0006048938,"about_ca_topic_score_gemma":0.000069896836,"teacher_disagreement_score":0.19089758,"about_ca_system_score_codex":0.00013463105,"about_ca_system_score_gemma":0.000045873403,"threshold_uncertainty_score":0.9997917},"labels":[],"label_agreement":null},{"id":"W2054534114","doi":"10.1371/journal.pone.0122929","title":"Predicting Outcome on Admission and Post-Admission for Acetaminophen-Induced Acute Liver Failure Using Classification and Regression Tree Models","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Public Health Service; National Institutes of Health","keywords":"Cart; Medicine; Acetaminophen; Receiver operating characteristic; Internal medicine; Creatinine; Hospital admission; Liver transplantation; Model for End-Stage Liver Disease; Area under the curve; Predictive value of tests; Transplantation; Anesthesia","score_opus":0.5028458773302806,"score_gpt":0.4316291406123929,"score_spread":0.07121673671788775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054534114","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99533767,0.00017151082,0.000384681,0.0018286572,0.00028843994,0.0014063275,0.000051332296,0.00014384759,0.000387516],"genre_scores_gemma":[0.99510324,0.00012058871,0.0032351324,0.00061015633,0.00025374236,0.00009846826,0.000045136454,0.00004188995,0.0004916416],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99807733,0.0003586522,0.00038848794,0.00051515206,0.00029749735,0.00036285594],"domain_scores_gemma":[0.998475,0.00025366968,0.00027613726,0.00020771603,0.00024988243,0.0005375848],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008279877,0.00029289944,0.00037015678,0.00018128152,0.0005673329,0.000049084414,0.00012058305,0.0006832183,0.000025056723],"category_scores_gemma":[0.00037949742,0.00025337082,0.00005438728,0.0001363667,0.00006034367,0.00045645356,0.00009946861,0.00077178684,0.000008892795],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014725394,0.0007569166,0.0077288947,0.00021981912,0.00019054166,0.000007759305,0.0016864773,0.00005953371,0.9735412,0.0002163935,0.000095997646,0.014023921],"study_design_scores_gemma":[0.003955791,0.0010588538,0.002736084,0.0004325222,0.00079532067,0.000025625548,0.0004834096,0.56152105,0.42696798,0.0010531507,0.0005217603,0.0004484619],"about_ca_topic_score_codex":0.000026379988,"about_ca_topic_score_gemma":0.000013576348,"teacher_disagreement_score":0.5614615,"about_ca_system_score_codex":0.00015921473,"about_ca_system_score_gemma":0.000096197014,"threshold_uncertainty_score":0.99999183},"labels":[],"label_agreement":null},{"id":"W2058293205","doi":"10.1007/s00204-015-1473-1","title":"Key factors of susceptibility to anti-tuberculosis drug-induced hepatotoxicity","year":2015,"lang":"en","type":"review","venue":"Archives of Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":71,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Drug metabolism; Drug; Detoxification (alternative medicine); Pharmacology; Medicine","score_opus":0.2451264166411303,"score_gpt":0.4703796794839414,"score_spread":0.22525326284281108,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058293205","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4554745,0.5195245,0.00008185134,0.00026015748,0.004380975,0.007130022,0.0018511015,0.00026362174,0.011033259],"genre_scores_gemma":[0.28014532,0.71763676,0.0005307985,0.00023062261,0.00037226352,0.00039543217,0.00020658605,0.00016181351,0.00032038224],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9902098,0.0045811497,0.0023462444,0.0012820158,0.00044306266,0.0011377283],"domain_scores_gemma":[0.9936,0.0025625094,0.0015966791,0.0011368105,0.00022734323,0.00087663607],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0020371848,0.001127906,0.004871574,0.0012176557,0.0002529098,0.0000151961,0.0014811248,0.0018341953,0.00045428987],"category_scores_gemma":[0.00090014515,0.0010286476,0.0014609401,0.0009867849,0.0007782766,0.00014993612,0.00079991797,0.0026871546,0.0001475451],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003619729,0.0026866596,0.0033064857,0.018686287,0.0019148637,0.00003492455,0.0055515883,0.00008670939,0.0199348,0.0012100056,0.0010582468,0.9451675],"study_design_scores_gemma":[0.0011833498,0.001333292,0.00067103177,0.0018407899,0.0020159946,0.000054099426,0.00026219466,0.00008384927,0.04229495,0.0014301018,0.9474243,0.0014060462],"about_ca_topic_score_codex":0.00031253416,"about_ca_topic_score_gemma":0.00043941027,"teacher_disagreement_score":0.9463661,"about_ca_system_score_codex":0.00027334163,"about_ca_system_score_gemma":0.0010207571,"threshold_uncertainty_score":0.9996137},"labels":[],"label_agreement":null},{"id":"W2059307186","doi":"10.3109/15563650.2013.775292","title":"Treating acetaminophen overdose: thresholds, costs and uncertainties","year":2013,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Alberta Health Services; Institute for Clinical Evaluative Sciences; McGill University Health Centre","funders":"","keywords":"Acetaminophen; Medicine; acetaminophen overdose; Acetylcysteine; Fulminant hepatic failure; Drug overdose; Regulatory agency; Guideline; Emergency medicine; Health care; Anesthesia; Intensive care medicine; Poison control; Surgery; Liver transplantation; Chemistry","score_opus":0.2090469815031133,"score_gpt":0.4820267390772933,"score_spread":0.27297975757418,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059307186","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9701786,0.00047456694,0.00008141804,0.003126347,0.0025353201,0.0010165678,0.000017251823,0.0002030359,0.022366913],"genre_scores_gemma":[0.9877845,0.00066958694,0.00038860593,0.0070552807,0.00081449153,0.0002525521,0.000015555348,0.00003286545,0.0029865655],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963683,0.001336302,0.0008490575,0.0006308535,0.00013191695,0.00068356557],"domain_scores_gemma":[0.99639046,0.0024659224,0.00027176534,0.00029497212,0.00012858478,0.00044831712],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0015370339,0.00031564786,0.00061233167,0.00011045037,0.0004693319,0.000059917747,0.0002813061,0.001326004,0.002869367],"category_scores_gemma":[0.000991782,0.00029063132,0.00016354278,0.0001999524,0.0008496652,0.00027138964,0.00023961128,0.0017381302,0.0009259029],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003669327,0.0009841964,0.38181335,0.000089546054,0.00041577633,0.000053448533,0.00056552154,0.00006480804,0.026624776,0.0089606745,0.018392578,0.5616684],"study_design_scores_gemma":[0.011795874,0.0037102099,0.44167125,0.00009706472,0.00053078117,0.00036290407,0.0012965894,0.013813858,0.02365431,0.030713737,0.47034916,0.002004266],"about_ca_topic_score_codex":0.00015536314,"about_ca_topic_score_gemma":0.0000910198,"teacher_disagreement_score":0.55966413,"about_ca_system_score_codex":0.00012737676,"about_ca_system_score_gemma":0.00009494678,"threshold_uncertainty_score":0.9999705},"labels":[],"label_agreement":null},{"id":"W2060143100","doi":"10.1016/j.bbrc.2004.03.022","title":"Glycogenolysis is directed towards ascorbate synthesis by glutathione conjugation","year":2004,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Pfizer","keywords":"Glycogenolysis; Glutathione; Chemistry; Intracellular; Glucagon; Biochemistry; Internal medicine; Endocrinology; Glycogen; Biology; Enzyme; Hormone","score_opus":0.2541508896378633,"score_gpt":0.4874408570670528,"score_spread":0.2332899674291895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060143100","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96876276,0.0011628582,0.00014079743,0.02497514,0.00007843773,0.0005838383,0.00031688673,0.00020303785,0.003776277],"genre_scores_gemma":[0.99470776,0.003206858,0.00068119494,0.000595134,0.00010628081,0.00033791774,0.000113660615,0.000018604283,0.00023261439],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997661,0.0007432377,0.0003031326,0.00040130963,0.00039931585,0.0004919861],"domain_scores_gemma":[0.9977021,0.0008767923,0.00007155576,0.0006455585,0.00033332536,0.00037065276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00092632015,0.00019031453,0.00024838696,0.000129044,0.0010281604,0.000068032976,0.0006580122,0.00043435258,0.0001521648],"category_scores_gemma":[0.00072937674,0.00017469884,0.000107032894,0.000833651,0.0011733137,0.00013167685,0.00039134367,0.0015101827,0.0002564299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011831911,0.00087351573,0.000031162006,0.000032334174,0.00009244626,0.0000014247844,0.00030950998,7.47233e-7,0.96078956,0.0027237984,0.0023070208,0.03272017],"study_design_scores_gemma":[0.0005693331,0.00009808334,0.00030418247,0.0000370977,0.00006238642,0.000005406334,0.000086543645,0.00098133,0.9508688,0.0069882493,0.039777048,0.0002215254],"about_ca_topic_score_codex":0.0005213735,"about_ca_topic_score_gemma":0.000011965646,"teacher_disagreement_score":0.037470028,"about_ca_system_score_codex":0.00018497955,"about_ca_system_score_gemma":0.00014201448,"threshold_uncertainty_score":0.79078823},"labels":[],"label_agreement":null},{"id":"W2060588027","doi":"10.1016/j.cgh.2008.02.053","title":"Impact of Liver Disease, Alcohol Abuse, and Unintentional Ingestions on the Outcomes of Acetaminophen Overdose","year":2008,"lang":"en","type":"article","venue":"Clinical Gastroenterology and Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":84,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Health Services; University of Calgary","funders":"","keywords":"Medicine; Acetaminophen; acetaminophen overdose; Liver disease; Alcohol; Emergency medicine; Alcoholic liver disease; Poison control; Alcohol abuse; Medical emergency; Drug overdose; Anesthesia; Internal medicine; Psychiatry; Acetylcysteine; Cirrhosis","score_opus":0.27869513746695035,"score_gpt":0.47307680254116724,"score_spread":0.1943816650742169,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060588027","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99721444,0.00016384036,0.00007332006,0.0015823124,0.00037586884,0.00033210113,0.000109547655,0.000021301168,0.00012729768],"genre_scores_gemma":[0.99595886,0.0017525296,0.000054364595,0.0020226517,0.000058073587,0.000035621724,0.000013658472,0.000010589355,0.00009363851],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9972979,0.0013185104,0.0006494863,0.00032814153,0.00008748763,0.00031850938],"domain_scores_gemma":[0.9973206,0.0017967705,0.00033313106,0.00021594216,0.00011078131,0.00022278847],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007286493,0.00020547627,0.0005822022,0.00011515694,0.0002529474,0.0000024967667,0.0001719291,0.00041447635,0.0002585174],"category_scores_gemma":[0.00040727027,0.00014385449,0.00025495086,0.000077608885,0.0023660518,0.000059656802,0.00010553195,0.00095484575,0.000012286778],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023928217,0.00073705206,0.99161285,0.00001942117,0.00054205523,0.0000340776,0.00016990956,0.000025816245,0.00028256982,0.003101915,0.0005002951,0.00058122555],"study_design_scores_gemma":[0.0017941165,0.0014186263,0.99428105,0.000010997193,0.00017587103,0.00012654677,0.000012875041,0.00085371756,0.00006945194,0.00077907747,0.00040027653,0.00007738726],"about_ca_topic_score_codex":0.00006843934,"about_ca_topic_score_gemma":0.000078929676,"teacher_disagreement_score":0.0026682154,"about_ca_system_score_codex":0.000020763659,"about_ca_system_score_gemma":0.00007649898,"threshold_uncertainty_score":0.87178165},"labels":[],"label_agreement":null},{"id":"W2061310149","doi":"10.1186/1471-2458-7-143","title":"Hospitalizations for acetaminophen overdose: a Canadian population-based study from 1995 to 2004","year":2007,"lang":"en","type":"article","venue":"BMC Public Health","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Calgary","funders":"Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; Canadian Liver Foundation","keywords":"Medicine; Acetaminophen; Population; Epidemiology; Demography; Internal medicine; Anesthesia; Environmental health","score_opus":0.18390180565907333,"score_gpt":0.4593972721212043,"score_spread":0.27549546646213097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061310149","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9428996,0.00009061174,0.04047504,0.008350244,0.0018300676,0.004730857,0.0007058032,0.00018425436,0.0007335282],"genre_scores_gemma":[0.98368984,0.0000018202206,0.0016765773,0.012856794,0.00048741567,0.0003530064,0.00058570417,0.000037131733,0.00031172534],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99727833,0.00049995945,0.00056461786,0.0004519822,0.0002048291,0.0010002643],"domain_scores_gemma":[0.99728537,0.00051939726,0.00017027011,0.00030017208,0.00017029923,0.0015545102],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0030971682,0.00021934116,0.00029346172,0.0004909276,0.0010428153,0.00007169833,0.00025789026,0.0003129012,0.0004831751],"category_scores_gemma":[0.00055439904,0.00024424656,0.00008222952,0.00073344744,0.000020142272,0.0001780562,0.00002438661,0.00040718462,0.000110276276],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000108441476,0.00087174174,0.963423,0.00006229347,0.00008060078,0.0000044038325,0.0026337276,0.0013947263,0.000076489356,0.0016086849,0.0049023624,0.024833543],"study_design_scores_gemma":[0.002192117,0.00045885466,0.76693976,0.000010981735,0.000029367657,8.184252e-7,0.00060442364,0.0027969603,0.00016418418,0.0003625453,0.22610207,0.00033788296],"about_ca_topic_score_codex":0.29919317,"about_ca_topic_score_gemma":0.6121999,"teacher_disagreement_score":0.3130067,"about_ca_system_score_codex":0.0020601363,"about_ca_system_score_gemma":0.0024812901,"threshold_uncertainty_score":0.99600863},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"observational","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":[],"domain":null,"study_design":"observational","genre":"empirical","about_ca_system":true,"about_ca_topic":true,"confidence":"low"}],"label_agreement":"agree"},{"id":"W2061688637","doi":"10.3109/1547691x.2013.867912","title":"Hepatic effects of aminoglutethimide: A model aromatic amine","year":2013,"lang":"en","type":"article","venue":"Journal of Immunotoxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Chemistry; Pharmacology; Aromatic amine; Drug; CD14; Biology; Biochemistry","score_opus":0.06480423372881822,"score_gpt":0.38321427427232524,"score_spread":0.318410040543507,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061688637","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918242,0.00085244584,0.0024799046,0.00069932913,0.0021950784,0.0009460274,0.0000041999465,0.000032530632,0.00096627267],"genre_scores_gemma":[0.99555105,0.00039529495,0.002100336,0.001197314,0.00019211497,0.00009607365,0.0000021882297,0.00003308551,0.0004325269],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99666095,0.0009799473,0.001368574,0.00019464505,0.00028437376,0.0005115013],"domain_scores_gemma":[0.99635136,0.0014055416,0.0013835612,0.00027689573,0.0003546557,0.0002279547],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001236209,0.00030025817,0.0008691232,0.0004601478,0.00016931232,0.000019646826,0.00051993027,0.00071871985,0.00041761267],"category_scores_gemma":[0.0008778233,0.0002627226,0.00032725706,0.00032585274,0.0003226714,0.00040296154,0.00009879519,0.0016688872,0.00014245529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002602242,0.00095059554,0.0014560054,0.000407745,0.00048289425,0.000057385765,0.0011875663,0.0023819308,0.9717575,0.00024625674,0.0011906854,0.019621212],"study_design_scores_gemma":[0.005477639,0.0025605604,0.011364672,0.00023258253,0.00053338124,0.0007345625,0.00017300718,0.04241066,0.91839117,0.015988953,0.0016655972,0.00046724107],"about_ca_topic_score_codex":0.00004047714,"about_ca_topic_score_gemma":0.000008033243,"teacher_disagreement_score":0.053366356,"about_ca_system_score_codex":0.00018051962,"about_ca_system_score_gemma":0.00024726024,"threshold_uncertainty_score":0.9999825},"labels":[],"label_agreement":null},{"id":"W2062255123","doi":"10.1007/s00335-011-9316-8","title":"Genetic analysis in mice identifies cysteamine as a novel partner for artemisinin in the treatment of malaria","year":2011,"lang":"en","type":"review","venue":"Mammalian Genome","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Cysteamine; Malaria; Artemisinin; Cystinosis; Plasmodium falciparum; Biology; Immunology; Plasmodium berghei; Drug resistance; Pharmacology; Genetics","score_opus":0.24595668969298792,"score_gpt":0.4492940457475132,"score_spread":0.20333735605452527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062255123","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03261056,0.9597737,0.00010984478,0.0000726744,0.0005638242,0.004920804,0.0006184163,0.000022788503,0.0013073772],"genre_scores_gemma":[0.024454664,0.9688692,0.00016511309,0.00010553018,0.00027880725,0.0025201407,0.0002791214,0.000053090662,0.0032743353],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967238,0.00094483746,0.0011439746,0.0005575332,0.00012800624,0.00050190656],"domain_scores_gemma":[0.9984076,0.00046458154,0.0005643753,0.00042302464,0.00005137841,0.00008904848],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012087377,0.00049139257,0.0016750003,0.00083358516,0.00010361372,0.00002543839,0.00049644755,0.00083369005,0.00039790326],"category_scores_gemma":[0.000029725046,0.00036896195,0.0007740366,0.001214928,0.00011210478,0.000048741465,0.000027002157,0.0005209153,0.00009760402],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009278639,0.0087970095,0.0020212582,0.022982191,0.010528865,0.00034632476,0.029123433,0.00074853026,0.0022806881,0.0016751805,0.00012850142,0.92044014],"study_design_scores_gemma":[0.0012478776,0.00037574567,0.0013590361,0.00024536115,0.0053366,0.000044272456,0.00014548888,0.00007410087,0.00018106906,0.00015946131,0.99043095,0.00040005177],"about_ca_topic_score_codex":0.00055070914,"about_ca_topic_score_gemma":0.0016626212,"teacher_disagreement_score":0.99030244,"about_ca_system_score_codex":0.00025454862,"about_ca_system_score_gemma":0.00014113371,"threshold_uncertainty_score":0.99987626},"labels":[],"label_agreement":null},{"id":"W2062647481","doi":"10.1371/journal.pone.0118862","title":"Analysis of IL-6, STAT3 and HSPA1L Gene Polymorphisms in Anti-Tuberculosis Drug-Induced Hepatitis in a Nested Case-Control Study","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Natural Science Foundation of China","keywords":"Haplotype; Single-nucleotide polymorphism; Odds ratio; Medicine; Case-control study; Nested case-control study; Genotype; Tuberculosis; Genotyping; Population; Genetics; Internal medicine; Biology; Pathology; Gene; Environmental health","score_opus":0.16818023493241074,"score_gpt":0.3689326017382927,"score_spread":0.20075236680588193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062647481","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970582,0.00022036358,0.000010981295,0.00037597722,0.00012860344,0.0017234136,0.00026950828,0.000053074702,0.00015986424],"genre_scores_gemma":[0.9991035,0.00012216152,0.00008855692,0.00030258126,0.000057559475,0.00024012105,0.000019212512,0.00002706049,0.000039242408],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99636686,0.0016177873,0.0007310907,0.0004924126,0.0003344605,0.00045736422],"domain_scores_gemma":[0.9986123,0.0004089308,0.00024325139,0.00029121994,0.00017130819,0.00027301023],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0019924683,0.0002824623,0.0010120921,0.0011772189,0.00010287626,0.000021700458,0.00015663946,0.0003330716,0.00012899484],"category_scores_gemma":[0.00022699383,0.00030723517,0.000090698995,0.0019201804,0.00008543716,0.00021784195,0.00007493396,0.00080679485,0.000013342926],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032212728,0.0071117,0.89928734,0.00003732994,0.0024778424,0.00081488956,0.006517621,0.00069472607,0.08008723,0.000010091597,0.000005344092,0.0026337425],"study_design_scores_gemma":[0.008804523,0.0007478992,0.81813437,0.000052518266,0.004685156,0.00004775504,0.001213719,0.0539159,0.11176949,0.00008804463,0.000014872138,0.00052576547],"about_ca_topic_score_codex":0.0111070825,"about_ca_topic_score_gemma":0.024321381,"teacher_disagreement_score":0.081153,"about_ca_system_score_codex":0.00018521649,"about_ca_system_score_gemma":0.000099831304,"threshold_uncertainty_score":0.99993795},"labels":[],"label_agreement":null},{"id":"W2062755408","doi":"10.1186/cc5559","title":"Pulmonary effects of desferrioxamine in the treatment of an experimental model of fulminant hepatic failure","year":2007,"lang":"en","type":"article","venue":"Critical Care","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Bayer Canada","keywords":"Medicine; Fulminant hepatic failure; Fulminant; Deferoxamine; Oxidative stress; Lung; Oxidative phosphorylation; Liver failure; Intensive care medicine; Gastroenterology; Pharmacology; Internal medicine; Biochemistry; Liver transplantation","score_opus":0.11027349893542529,"score_gpt":0.44843973394976566,"score_spread":0.3381662350143404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062755408","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99714655,0.0010568138,0.00018408487,0.000057195513,0.0001708261,0.0005719363,0.000039583145,0.000010124412,0.0007628927],"genre_scores_gemma":[0.9994397,0.000024132481,0.00031555968,0.000077052595,0.000048884416,0.000062638486,0.000015097692,0.000010254187,0.0000066746243],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987643,0.0003208723,0.00034592257,0.0001673224,0.00015421872,0.0002473608],"domain_scores_gemma":[0.9989517,0.00064545637,0.000052739044,0.00017827259,0.000087084794,0.00008476895],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030622736,0.00014205725,0.00028203308,0.000092848626,0.000063555446,0.0000024246867,0.00014168848,0.0002446656,0.000031536863],"category_scores_gemma":[0.00007340525,0.00010744077,0.0000955373,0.00014568737,0.00027557998,0.00007081731,0.000016598175,0.00022072303,0.000001496046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054608204,0.004030877,0.0034231371,0.000933735,0.000024375457,0.00013070212,0.017391123,0.00028973617,0.9532668,0.0021860546,0.0000024844692,0.017774899],"study_design_scores_gemma":[0.00088019687,0.0017826931,0.0017004667,0.000041485506,0.00008984361,0.000018496763,0.0044852304,0.0066527524,0.98380387,0.00037229276,0.00007234163,0.000100315825],"about_ca_topic_score_codex":0.000084278654,"about_ca_topic_score_gemma":0.00009429552,"teacher_disagreement_score":0.03053709,"about_ca_system_score_codex":0.00009335545,"about_ca_system_score_gemma":0.000041702508,"threshold_uncertainty_score":0.43813077},"labels":[],"label_agreement":null},{"id":"W2065234725","doi":"10.1111/j.1556-4029.2007.00482.x","title":"Acute Fatal Acetaminophen Overdose Without Liver Necrosis","year":2007,"lang":"en","type":"article","venue":"Journal of Forensic Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Office of the Chief Medical Examiner","funders":"","keywords":"Acetaminophen; acetaminophen overdose; Medicine; Necrosis; Liver injury; Centrilobular necrosis; Drug overdose; Antipyretic; Analgesic; Anesthesia; Pharmacology; Internal medicine; Poison control; Chemistry; Medical emergency; Antioxidant; Biochemistry","score_opus":0.14554588161613385,"score_gpt":0.43947323907616465,"score_spread":0.2939273574600308,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2065234725","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9895054,0.000344837,0.001121684,0.00050114386,0.0030928652,0.00015873053,0.000008535098,0.00002288895,0.0052439244],"genre_scores_gemma":[0.9948474,0.00019130061,0.0027753715,0.0011198809,0.00062448956,0.0000014012719,6.697715e-7,0.0000080505015,0.00043143012],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982468,0.00015375513,0.000498522,0.00018817463,0.0004570109,0.00045576968],"domain_scores_gemma":[0.9986646,0.00028225564,0.00050760986,0.000092151044,0.00019663617,0.0002567228],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0036591494,0.000162822,0.00027799088,0.00028070144,0.0005216903,0.00005724864,0.00040891353,0.00023481608,0.0002699563],"category_scores_gemma":[0.00013544428,0.00012453436,0.00017048065,0.0004917306,0.0007149021,0.0006091652,0.00006407217,0.0008068298,0.000052587195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015531986,0.00059966487,0.08836122,0.000057073084,0.0006778609,0.0007927164,0.005711079,0.00064212177,0.45464626,0.0035855388,0.008983752,0.43438953],"study_design_scores_gemma":[0.0022689977,0.0011064416,0.02521436,0.000068909925,0.00036155235,0.001750735,0.00074904226,0.0017296765,0.93055654,0.0039639524,0.0318226,0.0004071679],"about_ca_topic_score_codex":0.000031956006,"about_ca_topic_score_gemma":0.000053057065,"teacher_disagreement_score":0.4759103,"about_ca_system_score_codex":0.00009969746,"about_ca_system_score_gemma":0.00017060016,"threshold_uncertainty_score":0.5078364},"labels":[],"label_agreement":null},{"id":"W2065390851","doi":"10.1038/clpt.2010.355","title":"A Fresh Look at the Mechanism of Isoniazid-Induced Hepatotoxicity","year":2011,"lang":"en","type":"review","venue":"Clinical Pharmacology & Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":191,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Idiosyncrasy; Isoniazid; Metabolite; Clinical pharmacology; Mechanism (biology); Pharmacology; Medicine; Internal medicine; Tuberculosis; Pathology; Economics; Epistemology","score_opus":0.5197160465884401,"score_gpt":0.5517765724236009,"score_spread":0.032060525835160836,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2065390851","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0064536566,0.96424747,0.00011686476,0.0008202919,0.018488077,0.0057462095,0.0005223229,0.0003414178,0.0032636938],"genre_scores_gemma":[0.0020996665,0.97030216,0.00006842791,0.022783231,0.0020724128,0.0008228054,0.00008254528,0.00024041736,0.0015283222],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.98300576,0.009948041,0.0036642465,0.0015116375,0.00042284888,0.0014474789],"domain_scores_gemma":[0.98929065,0.0055443067,0.0029387206,0.0012522318,0.00036350352,0.0006106078],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"category_scores_codex":[0.005787132,0.0014683286,0.0041923756,0.00034765946,0.0009909209,0.000028597491,0.0024027398,0.0054556318,0.006254684],"category_scores_gemma":[0.00011151771,0.001078041,0.002667365,0.00085182686,0.0018505035,0.00014139118,0.0011102787,0.00863548,0.0018996688],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009693949,0.0032586453,0.0001527194,0.004660973,0.010584101,0.0001083549,0.00066690374,0.0000037033108,0.0023297477,0.0010589211,0.017989548,0.95821697],"study_design_scores_gemma":[0.0019309752,0.0007659889,0.000010367719,0.00049866084,0.013216073,0.00013157517,0.00003177711,0.00015470978,0.007498146,0.00091207435,0.9738602,0.0009894702],"about_ca_topic_score_codex":0.000047115136,"about_ca_topic_score_gemma":0.00008083672,"teacher_disagreement_score":0.9572275,"about_ca_system_score_codex":0.000489539,"about_ca_system_score_gemma":0.001092109,"threshold_uncertainty_score":0.99980664},"labels":[],"label_agreement":null},{"id":"W2066723064","doi":"10.1097/00003246-200301000-00048","title":"Fulminant hepatic failure secondary to acetaminophen poisoning: A systematic review and meta-analysis of prognostic criteria determining the need for liver transplantation","year":2003,"lang":"en","type":"review","venue":"Critical Care Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":195,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Medicine; Liver transplantation; Fulminant hepatic failure; Prothrombin time; Creatinine; Confidence interval; Internal medicine; Hepatic encephalopathy; Transplantation; Acetaminophen; Gastroenterology; acetaminophen overdose; Anesthesia; Cirrhosis","score_opus":0.2530570486359261,"score_gpt":0.4911788320406531,"score_spread":0.238121783404727,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066723064","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000047786278,0.9885527,0.0008538267,0.0009916192,0.00027077235,0.008489113,0.00064889813,0.000028634797,0.000116638534],"genre_scores_gemma":[0.009034933,0.98137826,0.00030748657,0.0038555423,0.00009860572,0.004772823,0.00040340662,0.00005993211,0.000088999666],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9946984,0.0025276789,0.0015199347,0.00055205624,0.00028127234,0.00042063833],"domain_scores_gemma":[0.9926837,0.005724478,0.00041494574,0.000381139,0.00052500144,0.000270721],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0021098822,0.00058635924,0.006109946,0.0003944404,0.00029157297,0.000024095518,0.0003182829,0.0005198674,0.0006201388],"category_scores_gemma":[0.0030203993,0.0003379069,0.0010969797,0.0008376738,0.00031908325,0.00007991692,0.00003939786,0.0008811813,0.000008140196],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014857643,0.000041309744,0.0000026063599,0.9729993,0.017437663,0.000026046508,0.0016602372,4.97093e-7,0.00000411653,0.00017372346,0.00014152021,0.00749815],"study_design_scores_gemma":[0.0003150888,0.0004220328,0.0000037099678,0.026602788,0.9421307,0.000101537364,0.00042453088,0.00006512931,0.000015135687,0.00002086376,0.029554823,0.00034368134],"about_ca_topic_score_codex":0.000012214696,"about_ca_topic_score_gemma":0.000040158768,"teacher_disagreement_score":0.94639647,"about_ca_system_score_codex":0.000082956976,"about_ca_system_score_gemma":0.00013256817,"threshold_uncertainty_score":0.9999073},"labels":[],"label_agreement":null},{"id":"W2068302586","doi":"10.1038/ncpneph0970","title":"Acute kidney injury associated with the use of traditional medicines","year":2008,"lang":"en","type":"review","venue":"Nature Clinical Practice Nephrology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":92,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Nephrotoxicity; Acute kidney injury; Medicine; Intensive care medicine; Renal function; Adverse effect; Drug; Kidney; Pharmacology; Internal medicine","score_opus":0.40386693021319225,"score_gpt":0.5442953070157929,"score_spread":0.14042837680260062,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068302586","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00023087494,0.95949703,0.00005058699,0.025047155,0.007507871,0.003155073,0.0020878473,0.0001910546,0.0022324931],"genre_scores_gemma":[0.00017145374,0.9202759,0.00026503156,0.075758755,0.0021749812,0.00019258136,0.0007676953,0.00007217066,0.00032141813],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9860366,0.010356648,0.0017204823,0.0007852064,0.00052015117,0.0005809231],"domain_scores_gemma":[0.95126283,0.0442573,0.0029300444,0.0005473596,0.00060551934,0.00039693102],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0032055867,0.00067196233,0.002482295,0.00022828188,0.00048116673,0.00002087302,0.00072549656,0.008449808,0.00044382655],"category_scores_gemma":[0.023845892,0.00041035993,0.00080477213,0.00082492805,0.0018032813,0.00044335338,0.00013478234,0.0198248,0.00009955073],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019325253,0.0016588409,0.000021586291,0.0005370683,0.0072070104,0.00036526617,0.00007755357,0.0000030943122,0.000007695184,0.0009379988,0.5764775,0.41077384],"study_design_scores_gemma":[0.0011543824,0.0012108276,0.00004762237,0.0005472371,0.007707297,0.0011050653,0.000005232663,0.000029538332,0.000005059103,0.00010518525,0.9877034,0.0003791733],"about_ca_topic_score_codex":0.000009903649,"about_ca_topic_score_gemma":0.000013286705,"teacher_disagreement_score":0.41122586,"about_ca_system_score_codex":0.0001304376,"about_ca_system_score_gemma":0.001627185,"threshold_uncertainty_score":0.99983484},"labels":[],"label_agreement":null},{"id":"W2068664917","doi":"10.1038/nbt.2838","title":"Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing","year":2014,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":622,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute","keywords":"Reactive oxygen species; Oxidative stress; Förster resonance energy transfer; Reactive nitrogen species; Drug; Chemistry; Pharmacology; Acetaminophen; In vivo; Toxicity; Biochemistry; Medicine; Biology; Fluorescence","score_opus":0.047018025339117704,"score_gpt":0.37096180051396443,"score_spread":0.32394377517484674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068664917","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956412,0.00051930704,0.0002815099,0.0013431282,0.00013843641,0.0009349534,0.0001544437,0.000063838634,0.0009231895],"genre_scores_gemma":[0.9962633,0.0001597195,0.003168796,0.00023365539,0.000073790245,0.00006384355,0.00000899067,0.000013894562,0.000013958542],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99830395,0.0006086344,0.00034679016,0.00033091914,0.00010492182,0.0003047727],"domain_scores_gemma":[0.9968569,0.0023495823,0.00037663901,0.00019722653,0.0001855049,0.000034111297],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015326337,0.00019177143,0.0003789483,0.00026084625,0.00014858137,0.0000060065763,0.0003165257,0.0010710243,0.00002065838],"category_scores_gemma":[0.0013368333,0.00015584855,0.00005801301,0.00042059578,0.0005754145,0.00007417543,0.000104665574,0.0015765398,0.0000032015455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002769135,0.00019781593,0.009688544,0.0001711621,0.000058939095,0.0000044259095,0.0022905306,0.000022290687,0.9439054,0.011911557,0.00011459504,0.031357843],"study_design_scores_gemma":[0.00097374374,0.00028503628,0.0060784123,0.000066034605,0.00006564378,0.00001811547,0.00081404386,0.0058960756,0.9791365,0.005719905,0.0007822107,0.00016425413],"about_ca_topic_score_codex":0.00017042713,"about_ca_topic_score_gemma":0.00010088453,"teacher_disagreement_score":0.03523114,"about_ca_system_score_codex":0.00004133221,"about_ca_system_score_gemma":0.00003954197,"threshold_uncertainty_score":0.82607204},"labels":[],"label_agreement":null},{"id":"W2069758416","doi":"10.1007/s00436-014-3831-y","title":"Protective effect of Thunbergia laurifolia extract on hemolysis during Plasmodium berghei infection","year":2014,"lang":"en","type":"article","venue":"Parasitology Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Plasmodium berghei; Hemolysis; In vivo; Biology; Traditional medicine; Hematocrit; Intraperitoneal injection; Inoculation; Pharmacology; Malaria; Immunology; Medicine","score_opus":0.13494166911389252,"score_gpt":0.5155468613682679,"score_spread":0.3806051922543754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069758416","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9858737,0.00004831813,0.00021294315,0.0003475518,0.00094136794,0.0014652562,0.000013020907,0.00012575662,0.010972063],"genre_scores_gemma":[0.9983929,0.000047084228,0.000022136437,0.00005187123,0.00036153148,0.00068094884,0.000010961396,0.00003711841,0.00039549035],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9905994,0.0069565903,0.0004376202,0.00064100494,0.000459115,0.00090628595],"domain_scores_gemma":[0.99610347,0.002791546,0.00019652951,0.00042035896,0.00025271808,0.00023536105],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.005207541,0.0003138609,0.0005871258,0.00071188353,0.00086270506,0.000021956763,0.00032000124,0.0010056781,0.0004049274],"category_scores_gemma":[0.0010071861,0.00028722273,0.0001942988,0.0007702902,0.00052130705,0.00014838057,0.000121618876,0.0032590546,0.00072781544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0081098005,0.0008845984,0.4619269,0.0006450826,0.0005747617,0.000055093908,0.0007785468,0.002235375,0.49496728,0.0015677862,0.00046078846,0.02779397],"study_design_scores_gemma":[0.002104912,0.0018832462,0.14361145,0.00004395406,0.000071441835,0.000070091264,0.000011903432,0.0020435795,0.84666264,0.0011203927,0.002137087,0.00023930514],"about_ca_topic_score_codex":0.00046509007,"about_ca_topic_score_gemma":0.00016287532,"teacher_disagreement_score":0.35169536,"about_ca_system_score_codex":0.00021412973,"about_ca_system_score_gemma":0.00007325085,"threshold_uncertainty_score":0.999958},"labels":[],"label_agreement":null},{"id":"W2071431766","doi":"10.1159/000079733","title":"Reported Case of Severe Hepatotoxicity Likely due to Fluconazole and &lt;i&gt;Not&lt;/i&gt; Desloratadine","year":2004,"lang":"en","type":"letter","venue":"Acta Haematologica","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Grand River Hospital","funders":"","keywords":"Desloratadine; Fluconazole; Medicine; Pharmacology; Dermatology; Antifungal","score_opus":0.10865908558040174,"score_gpt":0.36676924102319775,"score_spread":0.25811015544279603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071431766","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8755584,0.00062721234,0.00011376072,0.114003375,0.0017125,0.00304135,0.0010313151,0.00045156837,0.0034605246],"genre_scores_gemma":[0.81396055,0.00031564935,0.0006536898,0.18225166,0.00081339694,0.00040869488,0.0003500717,0.00011190105,0.0011343884],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99362,0.0013102177,0.0016983806,0.001557893,0.0004869909,0.0013265124],"domain_scores_gemma":[0.9955797,0.0010804618,0.0012967399,0.0010550452,0.0004244108,0.00056362466],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0015032691,0.0011526849,0.0022017534,0.0005872102,0.000783261,0.00008039344,0.00070994324,0.005037369,0.0011430276],"category_scores_gemma":[0.0008402466,0.0010969908,0.00040973557,0.00075327366,0.0006199394,0.00031455475,0.0005408367,0.0048284363,0.00021267668],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016164787,0.0010035188,0.00063710584,0.0029820295,0.0020017272,0.20239423,0.0016442116,0.00014796633,0.19005555,0.0014876163,0.5882658,0.00776379],"study_design_scores_gemma":[0.0022877788,0.0007063064,0.00044114728,0.0003121625,0.0008809058,0.09063419,0.000033464352,0.0002337441,0.108921655,0.002780123,0.79100704,0.0017614948],"about_ca_topic_score_codex":0.00015212175,"about_ca_topic_score_gemma":0.00036222598,"teacher_disagreement_score":0.20274125,"about_ca_system_score_codex":0.00029948386,"about_ca_system_score_gemma":0.0004203331,"threshold_uncertainty_score":0.99977005},"labels":[],"label_agreement":null},{"id":"W2072674441","doi":"10.2133/dmpk.dmpk-10-rv-085","title":"Involvement of the Immune System in Idiosyncratic Drug Reactions","year":2010,"lang":"en","type":"review","venue":"Drug Metabolism and Pharmacokinetics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Drug; Mechanism (biology); Biology; Liver injury; Mitochondrion; Immunology; Pharmacology; Cell biology","score_opus":0.08931070350487787,"score_gpt":0.39458165019212044,"score_spread":0.3052709466872426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072674441","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.003864602,0.98292524,0.000007333385,0.00012938042,0.007874973,0.0027192654,0.00035574165,0.000079296435,0.0020441532],"genre_scores_gemma":[0.017605446,0.97989285,0.000070090275,0.0001314093,0.0006901911,0.0004419516,0.00005508414,0.00008610054,0.0010269049],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.994323,0.0023425033,0.0017787952,0.0005979564,0.000366446,0.0005912763],"domain_scores_gemma":[0.9972184,0.0006152278,0.0011636168,0.00063766295,0.00012661153,0.00023852178],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0025143423,0.00074117095,0.0019958466,0.00045055128,0.0003895625,0.000042420797,0.0007898645,0.0008084909,0.00014831741],"category_scores_gemma":[0.000089068664,0.0005534824,0.0005782827,0.000986551,0.00035850503,0.00013333638,0.00035109103,0.0044652764,0.000041511896],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054872835,0.0005141729,0.000058626287,0.03362126,0.0005268358,0.000018600951,0.0015356577,0.000062108025,0.0033003802,0.0055339774,0.00056642294,0.95420706],"study_design_scores_gemma":[0.0010516049,0.0000075796083,0.000047819063,0.0025172327,0.0024885722,0.000060630406,0.00013348335,0.00030472502,0.010601156,0.0001062108,0.982178,0.0005029866],"about_ca_topic_score_codex":0.00026124873,"about_ca_topic_score_gemma":0.00008977191,"teacher_disagreement_score":0.98161155,"about_ca_system_score_codex":0.00011238287,"about_ca_system_score_gemma":0.00030501853,"threshold_uncertainty_score":0.99969167},"labels":[],"label_agreement":null},{"id":"W2073097431","doi":"10.1139/y10-065","title":"Influence of small doses of various drug vehicles on acetaminophen-induced liver injury","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Acetaminophen; Liver injury; Glutathione; Chemistry; Pharmacology; Ethanol; Dimethylformamide; Toxicity; Medicine; Biochemistry; Enzyme; Solvent","score_opus":0.05108077577581357,"score_gpt":0.34436193449720487,"score_spread":0.2932811587213913,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073097431","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962304,0.00024285413,0.00000265594,0.00040660353,0.0024095543,0.00028576306,0.000079252306,0.000009115881,0.00033376],"genre_scores_gemma":[0.9976021,0.00022890986,0.00007759696,0.0015816083,0.00041682547,0.000011068819,0.0000032652074,0.000018802264,0.000059813025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99758357,0.000924291,0.0006829076,0.0002497067,0.000087871544,0.00047166186],"domain_scores_gemma":[0.9973205,0.00084025547,0.0007348422,0.00015382262,0.0003790465,0.000571544],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001139953,0.00026028432,0.0006182042,0.00049107574,0.00025629703,0.000005242893,0.00042740648,0.0006373429,0.00093798],"category_scores_gemma":[0.00017117368,0.0002455913,0.00014083857,0.00023006543,0.0008671778,0.00013843918,0.000041465777,0.0022997104,0.0000152375615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00093673676,0.00016819552,0.0039020653,0.00016573966,0.00022180288,0.000062668405,0.001281526,0.00087293424,0.9860944,0.0007913272,0.0005478665,0.004954716],"study_design_scores_gemma":[0.0014335127,0.0008326685,0.029561283,0.0000270117,0.00020161305,0.00012334732,0.000046655136,0.00012907194,0.95811903,0.0015383712,0.00777818,0.00020924163],"about_ca_topic_score_codex":0.0014858046,"about_ca_topic_score_gemma":0.0021872562,"teacher_disagreement_score":0.027975377,"about_ca_system_score_codex":0.000044777822,"about_ca_system_score_gemma":0.0008244773,"threshold_uncertainty_score":0.99999964},"labels":[],"label_agreement":null},{"id":"W2073168642","doi":"10.1016/j.jhep.2015.02.050","title":"Targeting signal transduction pathways which regulate necrosis in acetaminophen hepatotoxicity","year":2015,"lang":"en","type":"letter","venue":"Journal of Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Signal transduction; Acetaminophen; Necrosis; Medicine; Cell biology; Pharmacology; Biology; Pathology","score_opus":0.13783269965165693,"score_gpt":0.37267818512741807,"score_spread":0.23484548547576115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073168642","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7767553,0.0017864372,0.000422417,0.20695904,0.010908188,0.0011878707,0.00015329043,0.00012021723,0.0017072844],"genre_scores_gemma":[0.8559985,0.00090646674,0.00060706877,0.13304393,0.0084915515,0.00008257511,0.0001796128,0.00017169562,0.00051857025],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99086136,0.004087767,0.002366332,0.00068675564,0.0007374693,0.001260325],"domain_scores_gemma":[0.9954301,0.00064987084,0.0021861948,0.00034160118,0.0010485079,0.000343731],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0049008993,0.000803338,0.0019425405,0.0011741082,0.00029682985,0.000056294077,0.00084749586,0.005507473,0.0012063014],"category_scores_gemma":[0.00042426863,0.00078823033,0.00050075096,0.0008387418,0.00029804747,0.00050901395,0.00011339863,0.013900815,0.00011716185],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001862289,0.0007078162,0.022299686,0.00070924975,0.0009040741,0.004223745,0.002997096,0.0024817232,0.071363874,0.000033869677,0.8796446,0.012772019],"study_design_scores_gemma":[0.004739808,0.0010554123,0.00038773572,0.00022678234,0.0006539971,0.0036740152,0.00013937164,0.0040750857,0.043919627,0.0054492666,0.9344133,0.0012656071],"about_ca_topic_score_codex":0.00018695401,"about_ca_topic_score_gemma":0.00014108338,"teacher_disagreement_score":0.07924328,"about_ca_system_score_codex":0.0010342852,"about_ca_system_score_gemma":0.001208341,"threshold_uncertainty_score":0.99970675},"labels":[],"label_agreement":null},{"id":"W2075465907","doi":"10.3109/13880209.2013.840318","title":"Protective potential of<i>Tamarindus indica</i>against gentamicin-induced nephrotoxicity","year":2014,"lang":"en","type":"article","venue":"Pharmaceutical Biology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Abbott (Canada)","funders":"Higher Education Commision, Pakistan; Higher Education Commission, Pakistan","keywords":"Gentamicin; Nephrotoxicity; Creatinine; Renal function; Medicine; Lactate dehydrogenase; Uric acid; Toxicity; Pharmacology; Internal medicine; Chemistry; Antibiotics; Biochemistry","score_opus":0.11133327887429335,"score_gpt":0.42488869347266717,"score_spread":0.3135554145983738,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075465907","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97555906,0.00009684405,0.007832024,0.001130572,0.0025388733,0.0020291244,0.00010127183,0.00027948114,0.010432776],"genre_scores_gemma":[0.993647,0.00009324712,0.00022196621,0.004642729,0.0009715243,0.00026507748,0.00005866076,0.000051753308,0.000048082013],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99423105,0.0026339956,0.00091171777,0.0008484715,0.00026216713,0.0011125808],"domain_scores_gemma":[0.9977249,0.0006487783,0.00042642874,0.00040451848,0.00021360334,0.0005817907],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0021318549,0.00053230824,0.00079113746,0.00033394888,0.0005114249,0.000020073243,0.0006282518,0.0013794163,0.00092154794],"category_scores_gemma":[0.0005207071,0.0005077359,0.0003163906,0.000549789,0.00078593974,0.00016807407,0.00033870808,0.0028441448,0.00041085464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00078820065,0.00059697893,0.0038785865,0.00008981614,0.00027895434,0.000012161016,0.0001606566,0.00012487208,0.8332925,0.0060273404,0.00012599089,0.15462397],"study_design_scores_gemma":[0.0039250143,0.0007038426,0.0027589526,0.000022504497,0.00022551617,0.000054895725,0.000046266563,0.012339127,0.88830096,0.005048723,0.08593077,0.00064341055],"about_ca_topic_score_codex":0.000128904,"about_ca_topic_score_gemma":0.000016972102,"teacher_disagreement_score":0.15398055,"about_ca_system_score_codex":0.00018535853,"about_ca_system_score_gemma":0.0001477854,"threshold_uncertainty_score":0.9999918},"labels":[],"label_agreement":null},{"id":"W2076947983","doi":"10.1016/s0300-483x(99)00142-0","title":"Hepatic drug metabolism and immunostimulation","year":2000,"lang":"en","type":"review","venue":"Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Cytochrome P450; Drug metabolism; Drug; Inflammation; Biotransformation; Cytochrome; Concomitant; Pharmacology; Biology; Enzyme; Immunology; Medicine; Internal medicine; Biochemistry","score_opus":0.16380996105045842,"score_gpt":0.4607382497479483,"score_spread":0.2969282886974899,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076947983","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014942702,0.9861365,0.000019944173,0.00012565516,0.0025363488,0.0021153947,0.00012202194,0.00025183233,0.007198041],"genre_scores_gemma":[0.00077429676,0.99383914,0.000119665994,0.00070905936,0.00073055975,0.0005257411,0.00020072199,0.00010010797,0.0030006873],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9946163,0.0026414155,0.0010247894,0.0007949865,0.000164997,0.0007574534],"domain_scores_gemma":[0.997506,0.0012215447,0.0005074515,0.00041708807,0.000053394364,0.00029452404],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0011187433,0.0007610864,0.0021786967,0.00050886034,0.0005250314,0.000047985952,0.00040184526,0.0021557494,0.003364227],"category_scores_gemma":[0.00012897425,0.0007127238,0.00040895943,0.00045721748,0.00033970558,0.00017808119,0.00016161226,0.0027226473,0.0014403217],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056677232,0.0001694995,0.000006475519,0.0031412567,0.00035366867,0.000036159505,0.0002470392,0.000017020766,0.000032708405,0.00057051214,0.0008098851,0.9945591],"study_design_scores_gemma":[0.0006900912,0.00007677913,0.000019203555,0.0004850108,0.0018842127,0.00025901303,0.000008323008,0.00016982111,0.00008599198,0.00058220397,0.99509525,0.00064408674],"about_ca_topic_score_codex":0.000057505837,"about_ca_topic_score_gemma":0.000030904914,"teacher_disagreement_score":0.9942854,"about_ca_system_score_codex":0.00019302304,"about_ca_system_score_gemma":0.0002917597,"threshold_uncertainty_score":0.9995781},"labels":[],"label_agreement":null},{"id":"W2077512653","doi":"10.1007/s13181-014-0431-2","title":"Prolonged Acetaminophen-Protein Adduct Elimination During Renal Failure, Lack of Adduct Removal by Hemodiafiltration, and Urinary Adduct Concentrations After Acetaminophen Overdose","year":2014,"lang":"en","type":"article","venue":"Journal of Medical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McGill University","keywords":"Acetaminophen; Medicine; Urine; Adduct; Urinary system; acetaminophen overdose; Internal medicine; Endocrinology; Pharmacology; Chemistry; Acetylcysteine; Biochemistry","score_opus":0.06438524563735741,"score_gpt":0.38245609535769903,"score_spread":0.3180708497203416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077512653","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867027,0.0013458921,0.00079215225,0.009054853,0.0009565656,0.0006980573,0.00005960984,0.000037089187,0.00035309436],"genre_scores_gemma":[0.99600446,0.00042060675,0.00094606046,0.0010341381,0.0011669062,0.00007227117,0.000028656468,0.00003282664,0.0002940453],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9948115,0.0020082588,0.0013412831,0.00041764663,0.00085143745,0.0005698865],"domain_scores_gemma":[0.99717784,0.00055946,0.0010282274,0.00023871595,0.00038647495,0.0006092968],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0032822154,0.0003553763,0.0007667648,0.00028421258,0.00030018677,0.00002668708,0.00043819274,0.0012032075,0.0015589034],"category_scores_gemma":[0.0018238571,0.00032922145,0.0001882395,0.000311663,0.00069904584,0.00051504764,0.00013555922,0.0021235284,0.000018409151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029121656,0.0015419986,0.0022353476,0.00037383867,0.00046182482,0.00034688998,0.0012845972,0.000096202806,0.9571577,0.001474079,0.0057886895,0.026326686],"study_design_scores_gemma":[0.014583406,0.0047396705,0.038437687,0.00042270156,0.0006657222,0.005885939,0.00039060242,0.003872762,0.83477736,0.002919559,0.09237724,0.00092733925],"about_ca_topic_score_codex":0.000010970488,"about_ca_topic_score_gemma":0.00002811891,"teacher_disagreement_score":0.12238031,"about_ca_system_score_codex":0.00017887093,"about_ca_system_score_gemma":0.00039151448,"threshold_uncertainty_score":0.99991596},"labels":[],"label_agreement":null},{"id":"W2077826343","doi":"10.1016/j.fct.2008.01.021","title":"Nanoparticles formulation of Cuscuta chinensis prevents acetaminophen-induced hepatotoxicity in rats","year":2008,"lang":"en","type":"article","venue":"Food and Chemical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":162,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Acetaminophen; Cuscuta; Traditional medicine; Chemistry; Pharmacology; Nanoparticle; Biology; Botany; Biochemistry; Medicine; Nanotechnology; Materials science","score_opus":0.12721449451662417,"score_gpt":0.3731791538041198,"score_spread":0.24596465928749564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077826343","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997772,0.00016210716,0.000014858205,0.00026818618,0.00035484193,0.0005904349,0.000025998568,0.00006316519,0.00074844755],"genre_scores_gemma":[0.999099,0.000112259855,0.00014679524,0.00034469704,0.00012305992,0.000088100795,0.00001540737,0.000020211295,0.00005044006],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99792206,0.00036780667,0.00064607983,0.0004142981,0.00015953807,0.00049022736],"domain_scores_gemma":[0.99906385,0.00027555382,0.00021890251,0.00018142418,0.00005691011,0.00020338326],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041288772,0.0002566766,0.00053068233,0.00015740102,0.00017067094,0.00000540588,0.00017397289,0.0007674461,0.00013338684],"category_scores_gemma":[0.0001902598,0.00025508672,0.000102822836,0.00034152146,0.00020581472,0.0001693926,0.00012725258,0.00074289367,0.000015396776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035210408,0.00069686474,0.043411683,0.00006588979,0.00006594592,0.000012452917,0.0009199654,0.000028353668,0.9462425,0.00040118315,0.0000462811,0.007756773],"study_design_scores_gemma":[0.0017852223,0.000552813,0.01321336,0.000018340215,0.000037311722,0.000071090486,0.000044294447,0.0014139175,0.9802833,0.001742991,0.00058738614,0.00024992996],"about_ca_topic_score_codex":0.000025230282,"about_ca_topic_score_gemma":0.000048135356,"teacher_disagreement_score":0.034040842,"about_ca_system_score_codex":0.000085892796,"about_ca_system_score_gemma":0.000067972745,"threshold_uncertainty_score":0.99999017},"labels":[],"label_agreement":null},{"id":"W2079350327","doi":"10.1016/j.taap.2012.08.015","title":"Acetaminophen-induced liver injury in rats and mice: Comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity","year":2012,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":418,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; McGill University; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; National Center for Research Resources; National Institute of General Medical Sciences","keywords":"Acetaminophen; Toxicity; Oxidative stress; Liver injury; Pharmacology; Mitochondrion; Mechanism (biology); Medicine; Metabolism; Chemistry; Biology; Internal medicine; Biochemistry","score_opus":0.0789508108398595,"score_gpt":0.37984430258553464,"score_spread":0.30089349174567515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079350327","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99479514,0.00080214697,0.000046099398,0.00038094318,0.0008895099,0.0023764414,0.000060190578,0.000024010073,0.0006255079],"genre_scores_gemma":[0.99802095,0.00028115895,0.0001989326,0.00067899784,0.0002601177,0.00050266663,0.000012164806,0.000019545098,0.00002549006],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99633497,0.0016382412,0.0007677667,0.00047326012,0.00015067807,0.00063508376],"domain_scores_gemma":[0.99839306,0.00077840826,0.00044960662,0.00014694763,0.000060173643,0.0001717903],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014950704,0.00036255075,0.0007881017,0.0003462211,0.00022590006,0.0000089403375,0.00023241903,0.0009483661,0.00024964637],"category_scores_gemma":[0.0000583475,0.0003233431,0.00004295698,0.00036855415,0.00069166627,0.00020305948,0.00019867957,0.0015847737,0.0000058868036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002127779,0.0016689454,0.008752708,0.00023685402,0.000115318966,0.000005398974,0.0077698845,0.000018681032,0.9592158,0.011933719,0.00010585743,0.00804906],"study_design_scores_gemma":[0.0036248956,0.00067228556,0.012343752,0.000022156366,0.00016832219,0.000025187697,0.0015906938,0.00042800125,0.9788707,0.0012510824,0.00070791907,0.0002950162],"about_ca_topic_score_codex":0.00008882944,"about_ca_topic_score_gemma":0.00018694269,"teacher_disagreement_score":0.019654894,"about_ca_system_score_codex":0.000062486004,"about_ca_system_score_gemma":0.00008101057,"threshold_uncertainty_score":0.99992186},"labels":[],"label_agreement":null},{"id":"W2079846425","doi":"10.1080/15287390701551407","title":"Cytotoxic Doses of Ketoconazole Affect Expression of a Subset of Hepatic Genes","year":2007,"lang":"en","type":"article","venue":"Journal of Toxicology and Environmental Health","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada; University of Ottawa","funders":"National Institute of Environmental Health Sciences","keywords":"Ketoconazole; Pharmacology; Cytochrome P450; Downregulation and upregulation; Aryl hydrocarbon receptor; Drug metabolism; Biology; Cytotoxicity; Gene; In vitro; Transcription factor; Biochemistry; Enzyme; Drug; Microbiology","score_opus":0.07566630694675096,"score_gpt":0.4083178302424979,"score_spread":0.33265152329574693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079846425","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99581575,0.0025263084,0.00032003375,0.00017650018,0.00048337225,0.00048227797,0.000069690024,0.000005175454,0.00012091785],"genre_scores_gemma":[0.9961385,0.0029271892,0.00048627236,0.00029507096,0.00009883853,0.0000060826274,0.0000063319508,0.00001352185,0.000028179547],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99748176,0.0006438401,0.0011622622,0.00015852801,0.00021796365,0.00033567083],"domain_scores_gemma":[0.9974697,0.00057536864,0.0015609185,0.00012640186,0.000024931362,0.00024264757],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002711929,0.00018434941,0.0006985824,0.00026617208,0.00013928709,0.0000017178631,0.00016955285,0.00040191406,0.00025016555],"category_scores_gemma":[0.000047195892,0.00016243523,0.00016042126,0.00011417131,0.00047630648,0.00013226713,0.00007194542,0.0006380468,0.0000021693618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016923536,0.0009837413,0.10881115,0.0004241768,0.00009374108,0.000016025266,0.0009821429,0.00015274335,0.86647135,0.000053011372,0.00008776746,0.02023182],"study_design_scores_gemma":[0.0020464554,0.0025995811,0.0938798,0.000116834104,0.000069080284,0.00020140348,0.0005619115,0.00008738052,0.8990134,0.00024286409,0.0010678729,0.0001134103],"about_ca_topic_score_codex":0.00002806204,"about_ca_topic_score_gemma":0.0000367078,"teacher_disagreement_score":0.032542083,"about_ca_system_score_codex":0.00012585512,"about_ca_system_score_gemma":0.000105569736,"threshold_uncertainty_score":0.6623916},"labels":[],"label_agreement":null},{"id":"W2082386503","doi":"10.1186/cc13389","title":"Determining late predictors of outcome for acetaminophen- induced acute liver failure using classification and regression tree modeling analysis","year":2014,"lang":"en","type":"article","venue":"Critical Care","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Acetaminophen; Cart; Liver transplantation; Liver failure; Outcome (game theory); Regression; Decision tree; Internal medicine; Intensive care medicine; Transplantation; Statistics; Anesthesia; Data mining","score_opus":0.3000956099145893,"score_gpt":0.4789608179722532,"score_spread":0.17886520805766393,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082386503","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9700242,0.00007691513,0.028796036,0.00015729756,0.00035493783,0.00033308446,0.00005622552,0.000051323746,0.00014993889],"genre_scores_gemma":[0.99742293,0.000011005417,0.0021399483,0.00015116569,0.00016325833,0.000043457756,0.000037421618,0.00001917325,0.000011606936],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99849945,0.0003243387,0.00040615458,0.0003459762,0.00013597083,0.0002880922],"domain_scores_gemma":[0.9988521,0.0004249499,0.00010725686,0.00017449397,0.00027327857,0.00016797542],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004643262,0.00018462841,0.00038339887,0.00021232275,0.00034245063,0.00002515004,0.00011613747,0.0005179107,0.000025340547],"category_scores_gemma":[0.00040861676,0.00017117795,0.0001595979,0.00025000586,0.000114095004,0.00017877232,0.000057430952,0.00046025665,0.0000017760003],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005389544,0.00018612479,0.21399412,0.0016484553,0.0010246848,0.000012427438,0.007449301,0.006152524,0.68270504,0.0023927921,0.000014554737,0.08388102],"study_design_scores_gemma":[0.0007781533,0.00015951144,0.0054674456,0.000042417665,0.0026896296,0.000004214129,0.0008368828,0.95368314,0.0357144,0.00026299493,0.00013732901,0.00022385968],"about_ca_topic_score_codex":0.000016510472,"about_ca_topic_score_gemma":0.00004265966,"teacher_disagreement_score":0.9475306,"about_ca_system_score_codex":0.000068068424,"about_ca_system_score_gemma":0.000025242109,"threshold_uncertainty_score":0.6980434},"labels":[],"label_agreement":null},{"id":"W2082779892","doi":"10.1007/s11011-010-9201-2","title":"N-Acetylcysteine attenuates cerebral complications of non-acetaminophen-induced acute liver failure in mice: antioxidant and anti-inflammatory mechanisms","year":2010,"lang":"en","type":"article","venue":"Metabolic Brain Disease","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":72,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Saint-Luc; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Proinflammatory cytokine; Acetylcysteine; Glutathione; Medicine; Pharmacology; Acetaminophen; Thioacetamide; Hepatic encephalopathy; Hepatoprotection; Brain damage; Cerebral edema; Internal medicine; Antioxidant; Endocrinology; Inflammation; Chemistry; Cirrhosis; Biochemistry","score_opus":0.036645618698220334,"score_gpt":0.34383471644565006,"score_spread":0.30718909774742975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082779892","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99387187,0.00025398156,0.00033456142,0.0032286497,0.0006550194,0.0011442268,0.00023786994,0.00008894778,0.00018489029],"genre_scores_gemma":[0.99741447,0.00011119684,0.0007853243,0.0011007388,0.00016687151,0.0002107827,0.00004524049,0.00004030642,0.00012506296],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9978005,0.00043238729,0.0005444543,0.0005279861,0.00020296485,0.00049166003],"domain_scores_gemma":[0.9985268,0.0002070479,0.00027342964,0.00039821494,0.0001219136,0.00047259819],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008237379,0.00034740398,0.00052242423,0.00030687198,0.0002728846,0.000031824777,0.00032733477,0.00039469954,0.00024634553],"category_scores_gemma":[0.00015298343,0.0003525294,0.00014509878,0.0004110472,0.0002578855,0.00028796738,0.00015277672,0.0010815458,0.00006771727],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001405137,0.00037723363,0.012606647,0.00014548919,0.00015299435,0.00003940583,0.0005719471,0.000024215464,0.9735013,0.0056261104,0.00017885111,0.00663524],"study_design_scores_gemma":[0.0036085185,0.000053309275,0.5761758,0.000042011292,0.00036560808,0.000039024897,0.00012226298,0.005858374,0.40466386,0.0011036511,0.0074385465,0.00052900607],"about_ca_topic_score_codex":0.0001091956,"about_ca_topic_score_gemma":0.00026486858,"teacher_disagreement_score":0.56883746,"about_ca_system_score_codex":0.000020810901,"about_ca_system_score_gemma":0.00015816267,"threshold_uncertainty_score":0.99989265},"labels":[],"label_agreement":null},{"id":"W2083286819","doi":"10.1016/j.taap.2004.03.023","title":"Role of tumor necrosis factor-α in the development of spontaneous hepatic toxicity in Long-Evans Cinnamon rats","year":2004,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Tumor necrosis factor alpha; Apoptosis; Internal medicine; Medicine; Endocrinology; Pathogenesis; Necrosis; Hepatitis; Toxicity; Immunology; Chemistry; Biochemistry","score_opus":0.0507779170586645,"score_gpt":0.35719835655149385,"score_spread":0.3064204394928293,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083286819","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951127,0.00022792125,0.000071836395,0.0003866089,0.00042483953,0.0016373891,0.000032930402,0.00003822697,0.0020675187],"genre_scores_gemma":[0.99750614,0.00009966896,0.00034407884,0.0015222066,0.00007218427,0.00039686196,0.000014441083,0.000024362516,0.000020079422],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99667,0.0007897889,0.0011030134,0.0005225647,0.00019307077,0.00072156364],"domain_scores_gemma":[0.9984366,0.0007611321,0.0004137832,0.0001957713,0.000053551328,0.00013914585],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015194104,0.0003878122,0.0007856996,0.00042948127,0.00022961554,0.0000076053216,0.00047774648,0.00066998106,0.0004218166],"category_scores_gemma":[0.000042471445,0.00034725026,0.000084138475,0.0006162412,0.0005617915,0.00008855151,0.00014441532,0.0014864118,0.000024216004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014128895,0.0018484417,0.010132631,0.00019044102,0.00011209649,0.00012453912,0.011547514,0.0020205905,0.96067744,0.0017167948,0.000015780957,0.010200847],"study_design_scores_gemma":[0.0043529565,0.00034176622,0.07003646,0.000029930632,0.00009339494,0.00015304514,0.00080556737,0.00027760284,0.91946304,0.0033803654,0.00071100716,0.00035483707],"about_ca_topic_score_codex":0.000090387126,"about_ca_topic_score_gemma":0.0025016468,"teacher_disagreement_score":0.05990383,"about_ca_system_score_codex":0.00022002944,"about_ca_system_score_gemma":0.00035729367,"threshold_uncertainty_score":0.99989796},"labels":[],"label_agreement":null},{"id":"W2083767828","doi":"10.1159/000211359","title":"Acetaminophen-lnduced Toxicity to Human Epidermoid Cell Line A431 and Hepatoblastoma Cell Line Hep G2, in vitro. Is Diminished by Silymarin","year":2009,"lang":"en","type":"article","venue":"Skin Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Sunnybrook Health Science Centre","funders":"","keywords":"Buthionine sulfoximine; Toxicity; Cytotoxicity; Glutathione; Viability assay; Pharmacology; MTT assay; Chemistry; Acetaminophen; Epidermoid carcinoma; Cell culture; Hep G2; Neutral red; Hepatotoxin; Biochemistry; Cell growth; In vitro; Biology; Medicine; Internal medicine; Cancer","score_opus":0.05639615770696305,"score_gpt":0.38840429087207673,"score_spread":0.3320081331651137,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083767828","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9824841,0.0006399967,0.00013538775,0.0071087303,0.0019048755,0.0021793053,0.00026400725,0.00026675343,0.005016821],"genre_scores_gemma":[0.9649744,0.0004131184,0.0003545197,0.030795671,0.0007782754,0.00028273943,0.00011749086,0.00008105968,0.0022027392],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9937005,0.0016383387,0.0012629916,0.001433013,0.00034816112,0.001617014],"domain_scores_gemma":[0.99744487,0.000625098,0.00041356566,0.00042475777,0.00015296695,0.00093872973],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0015012113,0.00087840715,0.0011481782,0.0006013128,0.000651483,0.000064585874,0.00074483396,0.001330351,0.0015142406],"category_scores_gemma":[0.0000738738,0.0009868802,0.00022165853,0.00087332714,0.00027862078,0.0003161572,0.00035833678,0.0027177085,0.00034249492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016251308,0.0024801355,0.00078437256,0.00011358253,0.000078027195,0.00019022741,0.0019423927,0.00017357711,0.9558143,0.000020276984,0.016897656,0.019880338],"study_design_scores_gemma":[0.007277936,0.001444259,0.0013266325,0.000013340107,0.00019385027,0.000057490975,0.00011608561,0.002997241,0.9396914,0.00050929515,0.04546889,0.0009035825],"about_ca_topic_score_codex":0.00021599366,"about_ca_topic_score_gemma":0.000079802085,"teacher_disagreement_score":0.028571231,"about_ca_system_score_codex":0.00034845292,"about_ca_system_score_gemma":0.00014738053,"threshold_uncertainty_score":0.99996614},"labels":[],"label_agreement":null},{"id":"W2085206713","doi":"10.1592/phco.2005.25.12.1725","title":"Effect of High‐Dose Vitamin C on Hepatic Cytochrome P450 3A4 Activity","year":2005,"lang":"en","type":"article","venue":"Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian College of Naturopathic Medicine; AIDS Vancouver; Ottawa Regional Cancer Foundation; University of Ottawa; Ottawa Hospital; Health Canada; HIV Legal Network","funders":"","keywords":"CYP3A4; Medicine; Confidence interval; Internal medicine; Vitamin; Cytochrome P450; Vitamin D and neurology; Endocrinology; Gastroenterology; Metabolism","score_opus":0.050894823094345745,"score_gpt":0.4208305880447083,"score_spread":0.36993576495036257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085206713","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909771,0.0025690955,0.000055401186,0.003121753,0.0014034444,0.0013065167,0.00003118102,0.000062849045,0.00047265203],"genre_scores_gemma":[0.9824605,0.010261815,0.000029089631,0.0050495286,0.0016827824,0.00006644802,0.0000027262622,0.00007184758,0.00037526365],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99143106,0.006165389,0.00096731045,0.0003495804,0.0004408332,0.0006458353],"domain_scores_gemma":[0.9951806,0.00275973,0.0012591261,0.00026478674,0.00020247191,0.00033329419],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00658295,0.00061387004,0.0010140248,0.00046550104,0.0008298411,0.000026510495,0.0007670376,0.00035962134,0.0023227534],"category_scores_gemma":[0.000030437579,0.00041873992,0.00035479455,0.00035408113,0.00070640346,0.0004504435,0.00006386492,0.0025422885,0.0000410932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01634213,0.0011274919,0.00037475326,0.00008125725,0.0009507092,0.000025337438,0.0020895095,0.00087698066,0.82554084,0.000089977315,0.0036906654,0.14881033],"study_design_scores_gemma":[0.01779913,0.004202178,0.0015113406,0.000041443614,0.000490302,0.00017357207,0.000034868583,0.0006711303,0.94949883,0.0003596443,0.024837915,0.00037965938],"about_ca_topic_score_codex":0.000045451543,"about_ca_topic_score_gemma":0.0000114511,"teacher_disagreement_score":0.14843068,"about_ca_system_score_codex":0.00016973879,"about_ca_system_score_gemma":0.000105701154,"threshold_uncertainty_score":0.99982643},"labels":[],"label_agreement":null},{"id":"W2085402348","doi":"10.1007/s40264-013-0045-7","title":"Idiopathic Acute Liver Injury in Paediatric Outpatients: Incidence and Signal Detection in Two European Countries","year":2013,"lang":"en","type":"article","venue":"Drug Safety","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; SickKids Foundation","funders":"Erasmus+; Vereniging Trustfonds Erasmus Universiteit Rotterdam","keywords":"Medicine; Incidence (geometry); Autoimmune hepatitis; Population; Cohort; Liver injury; Retrospective cohort study; Pediatrics; Internal medicine; Hepatitis; Environmental health","score_opus":0.02924156566193085,"score_gpt":0.3422572911791497,"score_spread":0.31301572551721885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085402348","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99635476,0.00038554193,0.00018462632,0.00026151576,0.00063016947,0.00080528803,0.000021079735,0.00007413208,0.0012828975],"genre_scores_gemma":[0.99755263,0.001120259,0.00003099036,0.0008818995,0.00019394743,0.00008766597,0.000008551839,0.000021967868,0.00010206765],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.997039,0.0015420702,0.00049430394,0.00036329558,0.00015968975,0.0004016447],"domain_scores_gemma":[0.99933785,0.0001617097,0.00015925635,0.00012885351,0.00007944831,0.00013287608],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019088718,0.00021902153,0.0002488147,0.00031324362,0.0002304664,0.000036711004,0.00016278743,0.00016903112,0.00021962132],"category_scores_gemma":[0.00006469877,0.00022687762,0.000043211752,0.00044446782,0.00013589868,0.0005505435,0.00013422426,0.0012283874,0.00045050206],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014889841,0.00052575,0.40474835,0.00022285024,0.00008062453,0.00020575558,0.013821449,0.00067141623,0.031348422,0.0002783667,0.00015961925,0.5464484],"study_design_scores_gemma":[0.009858402,0.0006239636,0.83612466,0.00031545645,0.00021532952,0.00012574907,0.0010413638,0.04352678,0.08110587,0.0028132044,0.022483038,0.0017661646],"about_ca_topic_score_codex":0.0012726545,"about_ca_topic_score_gemma":0.0012380033,"teacher_disagreement_score":0.54468226,"about_ca_system_score_codex":0.0002094323,"about_ca_system_score_gemma":0.00005225616,"threshold_uncertainty_score":0.9251801},"labels":[],"label_agreement":null},{"id":"W2086201901","doi":"10.1002/hep.23330","title":"Acetaminophen Dosing of Humans Results in Blood Transcriptome and Metabolome Changes Consistent With Impaired Oxidative Phosphorylation","year":2009,"lang":"en","type":"article","venue":"Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":87,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Chenomx (Canada)","funders":"National Institute of Environmental Health Sciences; National Center for Research Resources; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Metabolome; Oxidative phosphorylation; Transcriptome; Dosing; Acetaminophen; Pharmacology; Phosphorylation; Chemistry; Metabolite; Medicine; Biochemistry; Gene expression; Gene","score_opus":0.09354386124845877,"score_gpt":0.3644132617526492,"score_spread":0.27086940050419045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086201901","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994693,0.00091790955,0.00006592441,0.001782158,0.0002084804,0.00063436606,0.000071229144,0.000058790974,0.0015681592],"genre_scores_gemma":[0.99825436,0.00046735402,0.00036022166,0.0007044395,0.00003819012,0.000043283828,0.00003394447,0.000012229903,0.00008599501],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981024,0.00060241215,0.00042336414,0.00038472583,0.00011000286,0.00037707065],"domain_scores_gemma":[0.9992053,0.00020535174,0.0002442648,0.00015604297,0.000086213106,0.00010282107],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006891946,0.00022675325,0.0005099771,0.00026595627,0.00014446891,0.000008561509,0.00010430539,0.00041867958,0.00005097326],"category_scores_gemma":[0.00005687449,0.00020885638,0.000045530007,0.00031719322,0.0002789832,0.00011983507,0.000017107142,0.0005637397,0.0000052243577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0047748988,0.0010102981,0.09057864,0.00012781813,0.0003511684,0.00013710858,0.011699891,0.00009713178,0.8651009,0.0029384869,0.0000747447,0.023108872],"study_design_scores_gemma":[0.011203118,0.0021869452,0.13021104,0.00007700227,0.0005121917,0.00020729686,0.00061753485,0.0019619912,0.8458601,0.0016854851,0.004957119,0.0005201609],"about_ca_topic_score_codex":0.00021053769,"about_ca_topic_score_gemma":0.0008520702,"teacher_disagreement_score":0.039632402,"about_ca_system_score_codex":0.000044158412,"about_ca_system_score_gemma":0.00006849058,"threshold_uncertainty_score":0.8516916},"labels":[],"label_agreement":null},{"id":"W2086714780","doi":"10.1172/jci59755","title":"The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":763,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; McGill University; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; National Center for Research Resources; National Institute of General Medical Sciences","keywords":"Acetaminophen; DNA fragmentation; Fragmentation (computing); Mitochondrial DNA; Nuclear DNA; Toxicity; Apoptosis; DNA damage; Programmed cell death; Glutamate dehydrogenase; Mitochondrial toxicity; Mitochondrion; Liver injury; Biology; Pharmacology; Internal medicine; Medicine; Glutamate receptor; DNA; Biochemistry","score_opus":0.32416315730584017,"score_gpt":0.48222312165208997,"score_spread":0.1580599643462498,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086714780","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949006,0.00016845357,0.000102943995,0.0018458137,0.0024585219,0.0003784914,0.0000025958043,0.000016119991,0.00012649222],"genre_scores_gemma":[0.99621946,0.0005743996,0.0007253106,0.001617535,0.0008142827,0.000008549927,0.000002208918,0.000016283637,0.000021954354],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9964941,0.0016858467,0.001137996,0.00017252761,0.00022554303,0.00028396232],"domain_scores_gemma":[0.9971007,0.0015024148,0.0008546016,0.00009626727,0.000105397325,0.00034057954],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004866537,0.00016196043,0.0003345672,0.000117878146,0.00047467378,0.00007353599,0.00014065232,0.00048527334,0.000020409741],"category_scores_gemma":[0.0010684245,0.00013000846,0.0000873289,0.00015676836,0.00028889763,0.0007852876,0.00006096418,0.0015500237,0.000006699993],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007456988,0.0003626716,0.11046934,0.000087046916,0.00018146231,0.0000109757375,0.0076303035,0.000025816695,0.8401169,0.016777363,0.000244223,0.023348168],"study_design_scores_gemma":[0.012815398,0.0018809556,0.6660059,0.00035089112,0.00060575514,0.00012819115,0.006030383,0.011853527,0.18491913,0.10345062,0.0110267205,0.0009325098],"about_ca_topic_score_codex":0.00003420276,"about_ca_topic_score_gemma":0.000090628346,"teacher_disagreement_score":0.6551978,"about_ca_system_score_codex":0.00006870202,"about_ca_system_score_gemma":0.00007717091,"threshold_uncertainty_score":0.6734168},"labels":[],"label_agreement":null},{"id":"W2087395980","doi":"10.2165/00002018-200225080-00006","title":"Approaches Toward Repeated Supratherapeutic Doses of Paracetamol in Children","year":2002,"lang":"en","type":"article","venue":"Drug Safety","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Pharmacology; Intensive care medicine; Anesthesia","score_opus":0.23808226176066574,"score_gpt":0.37502647954484997,"score_spread":0.13694421778418422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087395980","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9861945,0.00091504666,0.00006395957,0.001181773,0.000321238,0.0008422641,0.000059810427,0.00010605297,0.010315373],"genre_scores_gemma":[0.99790615,0.0006034275,0.000101801794,0.00043875843,0.00010889356,0.000063391795,0.000032193806,0.000023240955,0.0007221613],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99776894,0.0007945137,0.0005331311,0.00035235856,0.000154951,0.00039611713],"domain_scores_gemma":[0.9992072,0.00021530285,0.00018426173,0.00024737266,0.000037332964,0.000108549386],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009563584,0.00022806233,0.0003605962,0.00017461285,0.00014309202,0.000010035845,0.00024821734,0.00035217984,0.0011814467],"category_scores_gemma":[0.00005826262,0.00022381445,0.00012282739,0.00045599038,0.00016342578,0.00015417239,0.000052632528,0.0008958603,0.00015556088],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014679075,0.003748792,0.6379461,0.00029116732,0.0009039397,0.000037884463,0.02469484,0.0057830554,0.035615493,0.003983702,0.0013310947,0.28419596],"study_design_scores_gemma":[0.012949684,0.0003820761,0.34511465,0.00013365256,0.00045342202,0.00022228603,0.0014722865,0.044537622,0.52284193,0.002572004,0.067472465,0.0018479142],"about_ca_topic_score_codex":0.00015576341,"about_ca_topic_score_gemma":0.00004587754,"teacher_disagreement_score":0.48722646,"about_ca_system_score_codex":0.000082440856,"about_ca_system_score_gemma":0.00002620553,"threshold_uncertainty_score":0.9997316},"labels":[],"label_agreement":null},{"id":"W2089246827","doi":"10.1111/jcpt.12223","title":"Interleukin-4 and interleukin-10 polymorphisms and antituberculosis drug-induced hepatotoxicity in Chinese population","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Pharmacy and Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Science Foundation of Beijing Municipality; National Natural Science Foundation of China; National Science Foundation","keywords":"Medicine; Pharmacology; Drug; Interleukin; Population; Internal medicine; Gastroenterology; Cytokine; Environmental health","score_opus":0.16433272566671314,"score_gpt":0.49582036370470284,"score_spread":0.3314876380379897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089246827","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99493706,0.00076373265,0.00008860441,0.0018524646,0.0015756818,0.00029745736,0.000008306105,0.000025352863,0.00045131994],"genre_scores_gemma":[0.9918656,0.0037243236,0.00015238082,0.0034292424,0.0007227749,0.0000057184793,0.0000031656054,0.000028116014,0.00006870046],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9959196,0.0015863839,0.0015803034,0.00034703768,0.00022247978,0.00034420413],"domain_scores_gemma":[0.9971359,0.0014260304,0.0007868285,0.00014221248,0.00013328504,0.00037576706],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0045153396,0.00032983796,0.0008315696,0.00029003306,0.00020882467,0.0000688845,0.0001959134,0.0003616161,0.00009817989],"category_scores_gemma":[0.00032593292,0.00027113085,0.00017625501,0.00023141134,0.00024729804,0.0004652115,0.00011728845,0.0020474722,0.0000060443217],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016326588,0.000474363,0.67828673,0.0000764929,0.00024554253,0.000023262184,0.00074687094,0.000013162362,0.014393089,0.00027596328,0.000029757359,0.3038021],"study_design_scores_gemma":[0.021339148,0.0015394078,0.8157145,0.00032477302,0.00075857085,0.0007184618,0.00019910124,0.039827757,0.022489687,0.013956282,0.08202784,0.0011044882],"about_ca_topic_score_codex":0.00013424599,"about_ca_topic_score_gemma":0.0001529004,"teacher_disagreement_score":0.3026976,"about_ca_system_score_codex":0.000044517565,"about_ca_system_score_gemma":0.000050683848,"threshold_uncertainty_score":0.9999741},"labels":[],"label_agreement":null},{"id":"W2090354988","doi":"10.1371/journal.pone.0049670","title":"Inflammatory Cascades Driven by Tumor Necrosis Factor-Alpha Play a Major Role in the Progression of Acute Liver Failure and Its Neurological Complications","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":96,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Saint-Luc","funders":"Canadian Institutes of Health Research","keywords":"Etanercept; Medicine; Liver injury; Tumor necrosis factor alpha; Internal medicine; Necrosis; Endocrinology","score_opus":0.11112872679087238,"score_gpt":0.3584954698719847,"score_spread":0.24736674308111234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090354988","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99678254,0.0005768784,0.0000037616808,0.0011243194,0.000040568862,0.0010187206,0.00016535002,0.000046076566,0.00024180724],"genre_scores_gemma":[0.9984764,0.00014655951,0.00013979358,0.0007689177,0.000076093806,0.00032231162,0.00002147396,0.000012635362,0.000035805082],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99848884,0.00055727264,0.00025501393,0.0001962183,0.00017899818,0.0003236821],"domain_scores_gemma":[0.9992657,0.00027108696,0.00015365651,0.00013295865,0.0000502773,0.00012632472],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003482753,0.00015844873,0.00022221706,0.0000714327,0.0002364561,0.000015212374,0.0002089566,0.00027817767,0.00013376957],"category_scores_gemma":[0.00004878975,0.00011932734,0.000042461354,0.00015549107,0.0001260451,0.00021415335,0.000083656734,0.00085115863,0.00003982946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015372805,0.002342162,0.21496627,0.00010719679,0.00020440132,0.0000085145075,0.004138952,0.0000017806088,0.7765009,0.0004008648,0.00019204992,0.0009831792],"study_design_scores_gemma":[0.0014341176,0.00039667764,0.31471482,0.000082109415,0.00045665263,0.000050579536,0.00012949832,0.00344479,0.6733773,0.00014148596,0.005445261,0.00032670944],"about_ca_topic_score_codex":0.000013053842,"about_ca_topic_score_gemma":0.000019218476,"teacher_disagreement_score":0.103123605,"about_ca_system_score_codex":0.000022022936,"about_ca_system_score_gemma":0.00002595162,"threshold_uncertainty_score":0.48660278},"labels":[],"label_agreement":null},{"id":"W2091704205","doi":"10.1016/j.tox.2010.04.014","title":"Epigallocatechin-3-gallate (EGCG) reduces liver inflammation, oxidative stress and fibrosis in carbon tetrachloride (CCl4)-induced liver injury in mice","year":2010,"lang":"en","type":"article","venue":"Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":258,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"University of Hong Kong","keywords":"Oxidative stress; Liver injury; Sirius Red; Nitrotyrosine; Fibrosis; Chemistry; Matrix metalloproteinase; Inflammation; Carbon tetrachloride; CCL4; Hepatic stellate cell; Endocrinology; Internal medicine; Medicine; Pharmacology; Nitric oxide synthase; Nitric oxide","score_opus":0.05357304172481248,"score_gpt":0.35799563933927164,"score_spread":0.30442259761445917,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091704205","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934006,0.00012671162,0.000007314331,0.00092131324,0.0016013449,0.0011767142,0.000040777715,0.00012594616,0.002599307],"genre_scores_gemma":[0.9979734,0.0004220586,0.00031399314,0.0004076397,0.00038470866,0.00025805688,0.000022669237,0.00004258512,0.00017493549],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965876,0.00095589476,0.00075422344,0.0007384931,0.00017841913,0.00078540744],"domain_scores_gemma":[0.99845415,0.0006210973,0.00030686083,0.00025640734,0.00011621456,0.00024525032],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.001436343,0.0004371473,0.0005611965,0.00070191355,0.00020392169,0.000040749383,0.00036984246,0.0015546869,0.00041721092],"category_scores_gemma":[0.0004000931,0.00047512728,0.000069904774,0.0006286037,0.0003547435,0.00039037882,0.00019734124,0.0033258395,0.00007575577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00062346266,0.00034636058,0.022372192,0.00009649782,0.000056574918,0.000110840214,0.0035135592,0.00006760809,0.94250447,0.0007039282,0.00002136615,0.029583117],"study_design_scores_gemma":[0.0015791575,0.00035260973,0.059580583,0.000051205305,0.000050599523,0.000043830176,0.00020389403,0.0028526024,0.9317122,0.00095120136,0.0021028144,0.00051930343],"about_ca_topic_score_codex":0.0015595353,"about_ca_topic_score_gemma":0.01214564,"teacher_disagreement_score":0.03720839,"about_ca_system_score_codex":0.00019767511,"about_ca_system_score_gemma":0.00018012767,"threshold_uncertainty_score":0.99977005},"labels":[],"label_agreement":null},{"id":"W2091868438","doi":"10.1016/s0002-9270(00)01936-5","title":"Gastrointestinal side effects associated with high doses of acetaminophen","year":2000,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Medicine; Acetaminophen; Side effect (computer science); Pharmacology","score_opus":0.032592099999006474,"score_gpt":0.3303066417996713,"score_spread":0.2977145418006648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091868438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99765563,0.000027141665,0.00035498856,0.0012355605,0.00019860327,0.00019131193,0.000013387783,0.00001947845,0.0003039024],"genre_scores_gemma":[0.997489,0.000047980433,0.00053587137,0.0016301235,0.00017096674,0.000008389469,0.0000024577787,0.00001982245,0.000095437055],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99677163,0.0019048182,0.000512166,0.00014663472,0.000203378,0.0004613507],"domain_scores_gemma":[0.99764687,0.0007512685,0.0011062317,0.000163663,0.00017664261,0.00015532672],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010346478,0.00020939544,0.00068711303,0.00012735641,0.00014140824,0.000008160031,0.00041314887,0.000048977014,0.00022591074],"category_scores_gemma":[0.0001404535,0.00013810134,0.00014190395,0.00023362761,0.0010386978,0.00009607433,0.000031767777,0.001104014,0.000016051907],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.14914358,0.0028336374,0.47790548,0.00010302263,0.0033772374,0.0011757199,0.0021274544,0.015484224,0.21097276,0.00015348983,0.0008794406,0.13584396],"study_design_scores_gemma":[0.014477392,0.12369711,0.77460766,0.0005405825,0.0016824928,0.016382147,0.0007041982,0.0006688218,0.06403919,0.0012807033,0.0014428725,0.000476835],"about_ca_topic_score_codex":0.000059304326,"about_ca_topic_score_gemma":0.000045753488,"teacher_disagreement_score":0.29670218,"about_ca_system_score_codex":0.00006986813,"about_ca_system_score_gemma":0.00006441072,"threshold_uncertainty_score":0.5631609},"labels":[],"label_agreement":null},{"id":"W2092869863","doi":"10.1002/hep.22536","title":"Hepatitis C is a predictor of acute liver injury among hospitalizations for acetaminophen overdose in the United States","year":2008,"lang":"en","type":"article","venue":"Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":103,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"American Gastroenterological Association","keywords":"Medicine; Internal medicine; Acetaminophen; Odds ratio; Liver disease; Hepatitis C; Alcoholic hepatitis; Chronic liver disease; Gastroenterology; Confidence interval; Cirrhosis; Liver injury; Alcoholic liver disease; Anesthesia","score_opus":0.0834461307115571,"score_gpt":0.3787560260265668,"score_spread":0.29530989531500973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092869863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99530804,0.00011577324,0.000861569,0.00079797924,0.00055113365,0.0012509129,0.0006733315,0.00005899838,0.00038228868],"genre_scores_gemma":[0.99261206,0.0028967876,0.00014603182,0.0033179577,0.00008115202,0.00046093148,0.00025477336,0.000022812763,0.00020747044],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9980793,0.0006369818,0.00045655965,0.00028724878,0.00013195598,0.00040794857],"domain_scores_gemma":[0.9987788,0.0005129442,0.00022149061,0.00024411004,0.00016021822,0.00008240099],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041444122,0.00020671773,0.00034623165,0.0002923137,0.00032488734,0.000006984067,0.00030935934,0.00050194544,0.00034007928],"category_scores_gemma":[0.0000930418,0.00017953408,0.00012256906,0.0006010984,0.00049049174,0.00014912506,0.00005934515,0.00052285974,0.000025118592],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032281294,0.0004057053,0.97425824,0.000081920276,0.00026785917,0.00007518605,0.010789988,0.00007750421,0.0008916494,0.002140077,0.010157305,0.0005317584],"study_design_scores_gemma":[0.0071166633,0.0021947,0.49517262,0.000070273716,0.0009595121,0.00035029495,0.000576272,0.21242937,0.076875485,0.009711415,0.1934279,0.0011154748],"about_ca_topic_score_codex":0.0019680185,"about_ca_topic_score_gemma":0.00039622534,"teacher_disagreement_score":0.4790856,"about_ca_system_score_codex":0.00007446538,"about_ca_system_score_gemma":0.000101515725,"threshold_uncertainty_score":0.7321187},"labels":[],"label_agreement":null},{"id":"W2094963496","doi":"10.1097/01.mop.0000152622.05168.9e","title":"An update of N-acetylcysteine treatment for acute acetaminophen toxicity in children","year":2005,"lang":"en","type":"review","venue":"Current Opinion in Pediatrics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Acetylcysteine; Acetaminophen; Medicine; Antidote; Toxicity; Regimen; acetaminophen overdose; Pharmacology; Intensive care medicine; Surgery; Antioxidant; Internal medicine; Chemistry","score_opus":0.2567901522576556,"score_gpt":0.5317952295339662,"score_spread":0.27500507727631057,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094963496","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004689506,0.980669,0.00014806142,0.00003448672,0.006911875,0.005141044,0.0023031863,0.0000674852,0.000035338104],"genre_scores_gemma":[0.0006951412,0.9923182,0.00021639073,0.000017246119,0.0030567136,0.001258874,0.0023370078,0.000070472386,0.000029936256],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99582624,0.0009495751,0.0015432348,0.0007874151,0.00021821112,0.0006753211],"domain_scores_gemma":[0.9979762,0.00034571651,0.00090189424,0.0004564131,0.00008553259,0.00023425325],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010709274,0.000720363,0.0019325657,0.0009738772,0.00011538991,0.000022626577,0.0005623806,0.0012781732,0.000084287305],"category_scores_gemma":[0.00006404919,0.0006768402,0.00052140956,0.0009809968,0.00008395135,0.0002241754,0.00009425518,0.0013632172,0.00004641807],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010255944,0.0017603541,0.0020249207,0.005302291,0.00016316534,7.95343e-7,0.00017081812,0.00014461527,0.000003627837,0.00014819826,0.00038087385,0.9897978],"study_design_scores_gemma":[0.0031428167,0.0005110145,0.00013680261,0.0008052793,0.0010992908,0.000020235562,0.000007481615,0.00037231282,0.00004967647,0.0000681141,0.99312425,0.00066270016],"about_ca_topic_score_codex":0.000025865847,"about_ca_topic_score_gemma":0.000020732494,"teacher_disagreement_score":0.9927434,"about_ca_system_score_codex":0.00078835414,"about_ca_system_score_gemma":0.0005212324,"threshold_uncertainty_score":0.9995683},"labels":[],"label_agreement":null},{"id":"W2095350286","doi":"10.1055/s-2008-1073115","title":"Acute Liver Failure in Children","year":2008,"lang":"en","type":"review","venue":"Seminars in Liver Disease","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":157,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Alberta Innovates - Health Solutions","keywords":"Medicine; Etiology; Encephalopathy; Coagulopathy; Intensive care medicine; Pediatrics; Hepatic encephalopathy; Liver failure; Disease; Broad spectrum; Liver disease; Psychiatry; Cirrhosis; Internal medicine","score_opus":0.09351755191291516,"score_gpt":0.4143598812185376,"score_spread":0.32084232930562245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095350286","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004205961,0.9907745,0.000002777199,0.000039285474,0.0006833469,0.0027212752,0.0006704659,0.00010239988,0.0007999495],"genre_scores_gemma":[0.001340129,0.99570495,0.00007023359,0.00033708033,0.00043419146,0.00065991486,0.00047102864,0.00008781525,0.00089464075],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9958696,0.0014221257,0.0007702792,0.00088887045,0.00026093813,0.00078819896],"domain_scores_gemma":[0.9983379,0.00029899238,0.0003242288,0.0004743352,0.000037898288,0.00052662904],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00042166188,0.000752641,0.0013386561,0.0007437675,0.00020975237,0.00002524431,0.0006646798,0.0014193245,0.00083725195],"category_scores_gemma":[0.00008562138,0.0007602852,0.00058083935,0.0008629699,0.00025513218,0.0002508538,0.00025153637,0.0033242174,0.00093824737],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016926283,0.000818984,0.005045402,0.0031237856,0.00040225108,0.002839961,0.00044034803,0.000024989324,0.0000015539808,0.000089402994,0.006608516,0.98043555],"study_design_scores_gemma":[0.0009343153,0.000050214625,0.0013977849,0.0048309793,0.0011224807,0.00034117416,0.000009048515,0.0001217162,0.000009629301,0.000084498366,0.9902118,0.00088638096],"about_ca_topic_score_codex":0.000101229714,"about_ca_topic_score_gemma":0.000099342644,"teacher_disagreement_score":0.98360324,"about_ca_system_score_codex":0.0005466058,"about_ca_system_score_gemma":0.00054975075,"threshold_uncertainty_score":0.99987704},"labels":[],"label_agreement":null},{"id":"W2095461027","doi":"10.1097/ccm.0b013e31829caf67","title":"Apoptosis or Necrosis in Acetaminophen-Induced Acute Liver Failure? New Insights From Mechanistic Biomarkers*","year":2013,"lang":"en","type":"letter","venue":"Critical Care Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Medicine; Acetaminophen; Gerontology; Family medicine; Pharmacology","score_opus":0.12979386730986675,"score_gpt":0.4004254837290891,"score_spread":0.27063161641922234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095461027","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.09578347,0.00403092,0.0011692676,0.8709944,0.017310074,0.0041266624,0.0006798255,0.0006069886,0.005298384],"genre_scores_gemma":[0.52272856,0.00040289728,0.0006246605,0.46048456,0.011737631,0.00054553547,0.0013852974,0.00019166144,0.0018991586],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9940531,0.0014518334,0.0010899807,0.0014039548,0.0007503471,0.0012507377],"domain_scores_gemma":[0.99480146,0.0031036718,0.00021388968,0.0007270884,0.00040892494,0.00074496906],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.00031275678,0.0010730445,0.0015875597,0.00068628014,0.00039433013,0.00008113313,0.0008361177,0.0051028864,0.012063531],"category_scores_gemma":[0.0013687826,0.0008599296,0.00026311647,0.00075601594,0.0006200968,0.00027997865,0.00024992978,0.007924644,0.0011215018],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005181153,0.00015234442,0.00006195434,0.0011578882,0.0007771057,0.0026525394,0.0040848562,7.9839646e-7,0.10391402,0.0003579651,0.8659333,0.020389115],"study_design_scores_gemma":[0.006225542,0.0015078919,0.00017271165,0.0012838881,0.0041304915,0.00010222644,0.00157192,0.00052825897,0.09811449,0.0075227073,0.87683284,0.0020070411],"about_ca_topic_score_codex":0.0049104635,"about_ca_topic_score_gemma":0.0007233733,"teacher_disagreement_score":0.42694512,"about_ca_system_score_codex":0.00063928036,"about_ca_system_score_gemma":0.00044528328,"threshold_uncertainty_score":0.99965626},"labels":[],"label_agreement":null},{"id":"W2096020887","doi":"10.1186/1752-1947-6-418","title":"Fulminant hepatic failure in association with quetiapine: a case report","year":2012,"lang":"en","type":"article","venue":"Journal of Medical Case Reports","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta Hospital; University of Alberta; University of Ottawa","funders":"","keywords":"Fulminant hepatic failure; Medicine; Fulminant; Quetiapine; Intensive care medicine; Hepatic encephalopathy; Disease; Intensive care unit; Pediatrics; Internal medicine; Psychiatry; Liver transplantation; Schizophrenia (object-oriented programming); Transplantation; Cirrhosis","score_opus":0.06450458546479507,"score_gpt":0.41545107675756443,"score_spread":0.35094649129276934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096020887","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99314433,0.00041270163,0.00027385473,0.0035912537,0.0017878535,0.0002771691,0.0000017577097,0.000019927349,0.00049115036],"genre_scores_gemma":[0.997964,0.00008707862,0.00021819405,0.00045435547,0.0010907027,0.000019622574,0.000002813784,0.00001807254,0.0001451555],"study_design_codex":"case_report","study_design_gemma":"case_report","domain_scores_codex":[0.9962227,0.0007458584,0.0013385725,0.00017235322,0.0010340322,0.0004865055],"domain_scores_gemma":[0.99664277,0.00043803008,0.0017531894,0.00016802801,0.00026219527,0.00073576777],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.012966424,0.00018663469,0.00045516496,0.00023421849,0.00015926156,0.000019103352,0.000060918104,0.00078570016,0.00077085814],"category_scores_gemma":[0.0028683825,0.00014000904,0.00012957433,0.0003370793,0.000064956264,0.000357556,0.000038838167,0.0024201947,0.0000074265945],"study_design_candidate":"case_report","study_design_consensus":"case_report","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010158867,0.0004636642,0.15934245,0.000060984697,0.000116498435,0.8324284,0.00073014596,0.000025748343,0.00025029288,0.000017545111,0.0013620973,0.0051005795],"study_design_scores_gemma":[0.0009271663,0.0001770843,0.0014112197,0.00011770637,0.00018931669,0.9461455,0.0003483364,0.00020029323,0.0037843627,0.00006735801,0.046471547,0.00016013118],"about_ca_topic_score_codex":0.00043963885,"about_ca_topic_score_gemma":0.001104123,"teacher_disagreement_score":0.15793122,"about_ca_system_score_codex":0.0004977243,"about_ca_system_score_gemma":0.0005040994,"threshold_uncertainty_score":0.99988127},"labels":[],"label_agreement":null},{"id":"W2096871000","doi":"10.1503/cmaj.111823","title":"Fluoroquinolone therapy and idiosyncratic acute liver injury: a population-based study","year":2012,"lang":"en","type":"article","venue":"Canadian Medical Association Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"McMaster University; Sunnybrook Hospital; Institute for Clinical Evaluative Sciences; Sunnybrook Health Science Centre; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Novo Nordisk; Ontario Ministry of Health and Long-Term Care; Institute for Clinical Evaluative Sciences; GlaxoSmithKline; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Moxifloxacin; Levofloxacin; Odds ratio; Internal medicine; Confidence interval; Population; Cefuroxime; Clarithromycin; Liver injury; Medical prescription; Antibiotics; Pharmacology","score_opus":0.0695917001333995,"score_gpt":0.3786009208762171,"score_spread":0.3090092207428176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096871000","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911179,0.00041311502,0.00003181905,0.005819364,0.0018032509,0.0004199285,0.000027988564,0.00003323984,0.00033339334],"genre_scores_gemma":[0.98657495,0.00020892755,0.000044981858,0.011546539,0.0014377157,0.000031618652,0.000009690075,0.000016141834,0.00012941421],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9971967,0.0011419925,0.00036366406,0.00014068912,0.0005680944,0.0005888815],"domain_scores_gemma":[0.9976852,0.00025721974,0.00021361394,0.00007664411,0.00014922098,0.001618096],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00325625,0.00015671384,0.00022695215,0.0002166065,0.0007394251,0.000061403814,0.00014172032,0.00064904906,0.003506135],"category_scores_gemma":[0.00047153916,0.00014753068,0.000063741354,0.00022260299,0.000027271664,0.00025441713,0.000012332805,0.0017303847,0.0001383574],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000069007234,0.00025989584,0.87299585,0.0000055208156,0.00033999595,0.00007553145,0.0012271338,0.0000049321916,0.00019517378,0.00009219892,0.004670879,0.12006386],"study_design_scores_gemma":[0.0036192352,0.0004481683,0.8161712,0.000025311501,0.00018925327,0.00018440495,0.00039734418,0.0018676157,0.00062208157,0.0001624526,0.17589588,0.0004170353],"about_ca_topic_score_codex":0.0022056936,"about_ca_topic_score_gemma":0.005784567,"teacher_disagreement_score":0.171225,"about_ca_system_score_codex":0.00068694097,"about_ca_system_score_gemma":0.0006758411,"threshold_uncertainty_score":0.9974048},"labels":[],"label_agreement":null},{"id":"W2097587582","doi":"10.1002/hep.25877","title":"Pathophysiological relevance of neutrophils in acetaminophen hepatotoxicity","year":2012,"lang":"en","type":"letter","venue":"Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Acetaminophen; In vivo; Chemokine; CXC chemokine receptors; Medicine; Pharmacology; Pathophysiology; Receptor; Liver injury; Neutropenia; Immunology; Chemokine receptor; Biology; Toxicity; Internal medicine","score_opus":0.15861583886202896,"score_gpt":0.40233611451757306,"score_spread":0.2437202756555441,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097587582","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8845537,0.001856506,0.000059611455,0.100454375,0.0057993373,0.0019084385,0.00038901856,0.00024638258,0.004732634],"genre_scores_gemma":[0.7577676,0.0011112469,0.00018176623,0.23713532,0.0025689746,0.0003728739,0.00024462963,0.00008790526,0.00052963075],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.992391,0.0033265783,0.0013429933,0.0009936881,0.00033857764,0.001607163],"domain_scores_gemma":[0.99653286,0.0014834786,0.0008786261,0.0007393498,0.00015822645,0.0002074679],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0011140782,0.0008147067,0.0018487008,0.00052782416,0.00017810812,0.000010428277,0.00082123396,0.007053929,0.0011853502],"category_scores_gemma":[0.00037125437,0.000800406,0.00042902128,0.0005618121,0.00075495953,0.0001883294,0.00030584808,0.010051055,0.00053352345],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018341293,0.0025008044,0.17507587,0.0032891922,0.00076876505,0.004714005,0.0015274315,0.00013611325,0.16783647,0.0020151495,0.6054808,0.034821272],"study_design_scores_gemma":[0.0015414394,0.00034209233,0.003154457,0.00008560614,0.0001908053,0.00024415582,0.000015134298,0.0008927984,0.029282738,0.0039338837,0.9593238,0.0009930896],"about_ca_topic_score_codex":0.00028309817,"about_ca_topic_score_gemma":0.00007341721,"teacher_disagreement_score":0.353843,"about_ca_system_score_codex":0.0003424954,"about_ca_system_score_gemma":0.00023346583,"threshold_uncertainty_score":0.9997277},"labels":[],"label_agreement":null},{"id":"W2098159917","doi":"10.1002/hep.27549","title":"Treatment of PD‐1−/− mice with amodiaquine and anti‐CTLA4 leads to liver injury similar to idiosyncratic liver injury in patients","year":2014,"lang":"en","type":"article","venue":"Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":173,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Amodiaquine; Liver injury; Medicine; Internal medicine; Gastroenterology; Immunology; Chloroquine","score_opus":0.048078129244732676,"score_gpt":0.3518078105280893,"score_spread":0.30372968128335665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098159917","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99692106,0.000085938125,0.0001230052,0.0006131354,0.0004114234,0.0012516954,0.000063898064,0.00004707176,0.00048277905],"genre_scores_gemma":[0.99673927,0.00023527924,0.00039986026,0.0022365584,0.00008477299,0.00016324136,0.000016256843,0.00003055249,0.00009421702],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976225,0.0007806322,0.00043391608,0.00051186775,0.0001358398,0.00051523343],"domain_scores_gemma":[0.99895626,0.00023790043,0.0001419994,0.00025796457,0.00011559471,0.00029027616],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032528487,0.00033023418,0.0006538721,0.00038643408,0.00013602138,0.000009684128,0.00015700959,0.00045318902,0.00015339139],"category_scores_gemma":[0.00008974595,0.0002929394,0.000055414665,0.00039237578,0.00016294279,0.00011237824,0.00008601408,0.00035455968,0.00015213115],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028993962,0.0012227335,0.9138529,0.00014419394,0.00010406639,0.00004286746,0.0024240613,0.00010818254,0.02209193,0.00030974412,0.00054899504,0.056250982],"study_design_scores_gemma":[0.009759218,0.023281647,0.40042007,0.00014253377,0.0004719196,0.000085360574,0.00009141132,0.010347945,0.4400339,0.00024863856,0.11360795,0.0015094135],"about_ca_topic_score_codex":0.00033677756,"about_ca_topic_score_gemma":0.0005266335,"teacher_disagreement_score":0.5134328,"about_ca_system_score_codex":0.00014879431,"about_ca_system_score_gemma":0.00006693811,"threshold_uncertainty_score":0.99995226},"labels":[],"label_agreement":null},{"id":"W2098745342","doi":"10.1373/clinchem.2008.103853","title":"Dehydrogenase Interference with Enzymatic Ethanol Assays: Forgotten but Not Gone","year":2008,"lang":"en","type":"letter","venue":"Clinical Chemistry","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"","keywords":"Ethanol; Chemistry; Chromatography; Medicine; Internal medicine; Biochemistry","score_opus":0.27160406661663244,"score_gpt":0.4503239925557123,"score_spread":0.17871992593907987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098745342","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6489744,0.000575224,0.0005061244,0.31176254,0.003631014,0.0020178247,0.00083563395,0.00091975124,0.030777466],"genre_scores_gemma":[0.32174546,0.0009711615,0.00029592606,0.6485291,0.01003092,0.00044396982,0.0007340503,0.00018606456,0.01706335],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99512863,0.0008319669,0.0014263289,0.0012080177,0.00043784265,0.0009672071],"domain_scores_gemma":[0.995526,0.0020981808,0.0008299645,0.0009011331,0.00021933677,0.0004253569],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0011801322,0.00081431307,0.0011996228,0.000068254856,0.0003539096,0.000045628167,0.0010018387,0.006478671,0.0014171504],"category_scores_gemma":[0.00077212794,0.0007338653,0.00050932955,0.0002372595,0.000943814,0.00012038771,0.00024336578,0.016335888,0.00083525234],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009916506,0.00070835097,0.0023978227,0.0019495421,0.0012078615,0.003451478,0.00014295965,0.000014232813,0.029092323,0.0000020722603,0.9535842,0.0064574857],"study_design_scores_gemma":[0.0017178899,0.00019296164,0.00002715971,0.0002267422,0.00038224846,0.00046298737,0.000012037094,0.0003429269,0.37684932,0.00010870512,0.6188514,0.00082558574],"about_ca_topic_score_codex":0.000016594217,"about_ca_topic_score_gemma":0.000003516965,"teacher_disagreement_score":0.347757,"about_ca_system_score_codex":0.00018147886,"about_ca_system_score_gemma":0.000510909,"threshold_uncertainty_score":0.9999427},"labels":[],"label_agreement":null},{"id":"W2100338188","doi":"10.1586/17512433.2014.904744","title":"A perspective on the epidemiology of acetaminophen exposure and toxicity in the United States","year":2014,"lang":"en","type":"review","venue":"Expert Review of Clinical Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":259,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Purdue Pharma (Canada)","funders":"","keywords":"Acetaminophen; Medicine; Analgesic; acetaminophen overdose; Toxicity; Drug overdose; Opioid; Epidemiology; Anesthesia; Pharmacology; Intensive care medicine; Poison control; Acetylcysteine; Emergency medicine; Internal medicine","score_opus":0.4224043631539794,"score_gpt":0.6106134601020781,"score_spread":0.18820909694809868,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2100338188","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012395512,0.9813245,0.00001820464,0.0092647085,0.0026995589,0.004018365,0.00009815787,0.00002620016,0.0013107732],"genre_scores_gemma":[0.00081642653,0.9451999,0.000045036373,0.051270775,0.0012762689,0.0012274304,0.00007057612,0.000040926552,0.00005263745],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9522247,0.042005163,0.0040921047,0.00082381064,0.00024766847,0.00060655386],"domain_scores_gemma":[0.94502527,0.05097753,0.0028963804,0.0006316019,0.0002785397,0.00019066255],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.025031667,0.0007108069,0.005667443,0.00028771238,0.0001887079,0.0000038525027,0.0013150186,0.0015096922,0.00088803086],"category_scores_gemma":[0.0077488683,0.00037913426,0.0011889595,0.00085556245,0.001710359,0.000051054943,0.0002597389,0.004920923,0.000051862837],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005273337,0.0022469417,0.0002846077,0.064265415,0.0019203668,0.000037450416,0.0017775629,0.00001942972,0.000018485938,0.009600172,0.07890978,0.8403925],"study_design_scores_gemma":[0.0008857169,0.0008718607,0.000059994232,0.01065686,0.0010013697,0.000040164043,0.00014134418,0.00010540956,0.000050249066,0.000808591,0.9850489,0.00032956232],"about_ca_topic_score_codex":0.0001555978,"about_ca_topic_score_gemma":0.000013343237,"teacher_disagreement_score":0.9061391,"about_ca_system_score_codex":0.00012850224,"about_ca_system_score_gemma":0.00029917102,"threshold_uncertainty_score":0.99986607},"labels":[],"label_agreement":null},{"id":"W2103293224","doi":"10.1136/jech.2010.126847","title":"For peace and pain: the medical legitimisation of Afghanistan's poppy crop","year":2011,"lang":"en","type":"article","venue":"Journal of Epidemiology & Community Health","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Institute of Population and Public Health","funders":"","keywords":"Afghan; Opium; Poppy; Status quo; Medicine; Politics; Public health; Denial; Law; Political science; Nursing","score_opus":0.5371626596611218,"score_gpt":0.5298948962131532,"score_spread":0.007267763447968534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103293224","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9107953,0.0033891515,0.034573354,0.046702832,0.0014914514,0.00095803605,0.000039688228,0.000027252572,0.0020229656],"genre_scores_gemma":[0.9767319,0.002968214,0.0026346059,0.017348876,0.0002417956,0.000017227045,0.0000067992687,0.000012360844,0.000038207243],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9798188,0.018326264,0.0012407112,0.00011241775,0.00012424453,0.0003775545],"domain_scores_gemma":[0.9844699,0.013171605,0.001463911,0.00028293688,0.0002693846,0.00034226684],"candidate_categories":["metaresearch","research_integrity"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.060137242,0.00014618978,0.00065422914,0.00011274888,0.000844385,0.0000028431714,0.00044786875,0.00046792327,0.0001715224],"category_scores_gemma":[0.010890706,0.00010443008,0.00015622406,0.000107735126,0.000611205,0.0001039763,0.00008182504,0.0029441933,0.0000015876453],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008801873,0.0041096807,0.18881597,0.0026612051,0.0015945879,0.000026382162,0.043888092,0.0002490901,0.0028317142,0.09334847,0.06875932,0.5849136],"study_design_scores_gemma":[0.008740505,0.0139315585,0.13894027,0.0007089185,0.0004345837,0.0015156744,0.0092587685,0.009287358,0.0050737574,0.122297116,0.689134,0.0006774918],"about_ca_topic_score_codex":0.0016950184,"about_ca_topic_score_gemma":0.001233809,"teacher_disagreement_score":0.6203747,"about_ca_system_score_codex":0.00012190102,"about_ca_system_score_gemma":0.00049722154,"threshold_uncertainty_score":0.99935603},"labels":[],"label_agreement":null},{"id":"W2103691399","doi":"10.1139/o10-023","title":"Hepatoprotection by carotenoids in isoniazid–rifampicin induced hepatic injury in rats","year":2010,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Carotenoid; Isoniazid; Lipid peroxidation; Chemistry; Superoxide dismutase; Catalase; Rifampicin; Hepatoprotection; Oxidative stress; Antioxidant; Internal medicine; Pharmacology; Endocrinology; Biochemistry; Medicine; Enzyme; Glutathione; Pathology; Antibiotics","score_opus":0.03495657090667742,"score_gpt":0.35497559009272905,"score_spread":0.32001901918605163,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103691399","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950374,0.00023681777,0.000013488581,0.00031058278,0.000828286,0.0004913435,0.000045800603,0.00005555756,0.0029807657],"genre_scores_gemma":[0.9985083,0.0002120408,0.000037485715,0.00047520502,0.00018613691,0.00017975637,0.0000546882,0.00001695907,0.00032946892],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981594,0.0003445562,0.00041360632,0.00053507136,0.000059015772,0.0004883153],"domain_scores_gemma":[0.99936336,0.000105528656,0.00013053491,0.00020745154,0.0000327331,0.00016038289],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00078318274,0.0002750932,0.00031733222,0.00013467361,0.0001518293,0.000014965948,0.00017654592,0.0015958358,0.00020764883],"category_scores_gemma":[0.00009523076,0.00028590683,0.000049663387,0.00030904528,0.00018302747,0.00006780195,0.00007392719,0.0022778823,0.00002866915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020431253,0.00023865623,0.04847583,0.00007791447,0.00000929976,0.0000077939685,0.00017553504,0.000001516264,0.92747414,0.000028903383,0.000085478416,0.023220623],"study_design_scores_gemma":[0.0010393424,0.0001640465,0.0016300848,0.000012965855,0.000012179612,0.00001455774,0.00006933753,0.00055739115,0.9840534,0.00048461824,0.011650333,0.00031173995],"about_ca_topic_score_codex":0.0010589866,"about_ca_topic_score_gemma":0.00038090075,"teacher_disagreement_score":0.056579266,"about_ca_system_score_codex":0.00007477606,"about_ca_system_score_gemma":0.000087679735,"threshold_uncertainty_score":0.9999593},"labels":[],"label_agreement":null},{"id":"W2104235533","doi":"10.3109/15563650.2015.1096370","title":"Response to Letter to the Editor: External validation of the paracetamol-aminotransferase multiplication product to predict hepatotoxicity from paracetamol overdose","year":2015,"lang":"en","type":"letter","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Acetaminophen; Medicine; Pharmacology; Multiplication (music); Drug overdose; Toxicology; Anesthesia; Emergency medicine; Poison control; Mathematics; Biology","score_opus":0.18293540952107357,"score_gpt":0.4488227596826268,"score_spread":0.26588735016155324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2104235533","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5210885,0.0000528945,0.0011415539,0.44807774,0.022518238,0.00579778,0.0011329422,0.00011253344,0.00007783484],"genre_scores_gemma":[0.35979894,0.00002735038,0.00044567714,0.5894521,0.047029134,0.0017113853,0.00014691435,0.00011013532,0.0012784],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.979188,0.014280384,0.002411485,0.0019075832,0.0010379136,0.001174586],"domain_scores_gemma":[0.9889426,0.0064600143,0.0008841614,0.0022737791,0.0006849212,0.00075450365],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00965069,0.00089546223,0.0014566843,0.00030990457,0.00057866727,0.00008280985,0.0023880946,0.0038990958,0.000481925],"category_scores_gemma":[0.00804423,0.000654817,0.0007027742,0.0008840333,0.00056973565,0.00018188829,0.0007605342,0.0083155325,0.0016651335],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0058152378,0.00066359394,0.0054872045,0.000055487937,0.00029717237,0.000045290322,0.0009201928,0.0015405244,0.061615843,0.000007212985,0.91794753,0.0056047062],"study_design_scores_gemma":[0.0016105472,0.0010567962,0.012655347,0.000100631005,0.0003949012,0.00001754885,0.00001362132,0.00026399313,0.101963945,0.00024422453,0.8810396,0.000638817],"about_ca_topic_score_codex":0.00019824703,"about_ca_topic_score_gemma":0.00015419148,"teacher_disagreement_score":0.16128956,"about_ca_system_score_codex":0.0006728794,"about_ca_system_score_gemma":0.00073451886,"threshold_uncertainty_score":0.99959034},"labels":[],"label_agreement":null},{"id":"W2110406985","doi":"10.2310/8000.2013.130957","title":"Colchicine overdose with coingestion of nonsteroidal antiinflammatory drugs","year":2014,"lang":"en","type":"article","venue":"Canadian Journal of Emergency Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Sinai Hospital; University of Toronto","funders":"","keywords":"Medicine; Toxicity; Colchicine; Ingestion; Vomiting; Intensive care unit; Nausea; Drug overdose; Pharmacology; Anesthesia; Internal medicine; Poison control; Emergency medicine","score_opus":0.14871194612564811,"score_gpt":0.4137172923571347,"score_spread":0.26500534623148664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110406985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97496796,0.00064459175,0.00072804943,0.0019901695,0.0075832237,0.00023333431,0.000012148631,0.000010168588,0.013830334],"genre_scores_gemma":[0.9976687,0.00021704753,0.00006144153,0.00031995526,0.0012640916,0.0000030730246,0.000005046372,0.00001918928,0.0004414795],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981875,0.00036557234,0.00076167367,0.00013408547,0.000228052,0.00032313567],"domain_scores_gemma":[0.9979172,0.00012341012,0.00064429484,0.00014508505,0.00045131033,0.0007187124],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0017828038,0.00017902695,0.0004147121,0.00040775278,0.00019262842,0.0000021390924,0.0002099943,0.00021304916,0.00263026],"category_scores_gemma":[0.00034224676,0.0001410152,0.00007313541,0.0003434798,0.0002639076,0.00014386405,0.000007125094,0.0007871082,0.000010614602],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033876046,0.00045589785,0.48543307,0.0014302209,0.0016160696,0.0004579171,0.025621606,0.0048841825,0.291339,0.012826582,0.08545197,0.08709586],"study_design_scores_gemma":[0.010765809,0.005579587,0.052121963,0.0012356361,0.0010300886,0.00034946922,0.0015821175,0.0025369367,0.04576596,0.0016948082,0.8765664,0.00077121484],"about_ca_topic_score_codex":0.0017286851,"about_ca_topic_score_gemma":0.0070557804,"teacher_disagreement_score":0.79111445,"about_ca_system_score_codex":0.00007858461,"about_ca_system_score_gemma":0.0005027833,"threshold_uncertainty_score":0.9982815},"labels":[],"label_agreement":null},{"id":"W2111313602","doi":"10.5858/2003-127-1493-rh","title":"Ramipril-Associated Hepatotoxicity","year":2003,"lang":"en","type":"article","venue":"Archives of Pathology & Laboratory Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Toronto General Hospital; St. Michael's Hospital","funders":"","keywords":"Medicine; Ramipril; Cholestasis; Gastroenterology; Internal medicine; Jaundice; Liver biopsy; Elevated alkaline phosphatase; Bile duct; Elevated transaminases; Endoscopic retrograde cholangiopancreatography; Hepatitis; Liver injury; Pathology; Biopsy; Pancreatitis; Alkaline phosphatase","score_opus":0.08027284981876577,"score_gpt":0.39386014406890857,"score_spread":0.3135872942501428,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2111313602","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9671023,0.0008848298,0.0007228929,0.0007121314,0.0017818626,0.0005516823,0.0001191689,0.00016194723,0.02796321],"genre_scores_gemma":[0.99629307,0.00044124338,0.00042309766,0.0021440622,0.00017237898,0.0000615183,0.000035481404,0.00003490744,0.00039426898],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99494904,0.0030716418,0.0006904369,0.00047630488,0.00022041684,0.0005921862],"domain_scores_gemma":[0.99755377,0.001180975,0.00042679184,0.00038810977,0.00015023217,0.00030012388],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0020342323,0.0003321423,0.00068517943,0.0003235303,0.00030372042,0.0000033855476,0.00030835794,0.0005248909,0.0009735893],"category_scores_gemma":[0.002006696,0.0003037043,0.00011171196,0.0005824331,0.0015535243,0.00010679706,0.000057282265,0.00129375,0.00006657136],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000305599,0.00078979594,0.066796236,0.00010958008,0.00026121922,0.0003699336,0.00435577,0.00007217921,0.9011314,0.017351655,0.0012702971,0.007186325],"study_design_scores_gemma":[0.010066885,0.0018899174,0.048724633,0.00021223964,0.00047778888,0.00019050374,0.0012382613,0.00067959185,0.7321763,0.019766362,0.18364023,0.0009372618],"about_ca_topic_score_codex":0.000026471705,"about_ca_topic_score_gemma":0.00005250948,"teacher_disagreement_score":0.18236993,"about_ca_system_score_codex":0.000056885543,"about_ca_system_score_gemma":0.00024308487,"threshold_uncertainty_score":0.9999415},"labels":[],"label_agreement":null},{"id":"W2111535205","doi":"10.1503/cmaj.091948","title":"Polypharmacy, multiple natural health products and hepatotoxicity","year":2011,"lang":"en","type":"article","venue":"Canadian Medical Association Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Health Canada; Alberta Innovates; Canadian Patient Safety Institute","keywords":"Polypharmacy; Depression (economics); Jaundice; Natural history; Medicine; Asthma; Wine; Alcohol consumption; Environmental health; Psychiatry; Alcohol; Intensive care medicine; Internal medicine; Food science","score_opus":0.09501712230798372,"score_gpt":0.36761312933602347,"score_spread":0.27259600702803977,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2111535205","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9578089,0.0010979924,0.000049817474,0.031282425,0.005738036,0.0005276271,0.000059801096,0.00008189891,0.0033535175],"genre_scores_gemma":[0.96933246,0.0005624294,0.00017519327,0.028053729,0.0014239931,0.000015674947,0.000008094533,0.00001858944,0.00040984375],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.996884,0.0009853678,0.00049675134,0.00025854012,0.0005736365,0.00080170296],"domain_scores_gemma":[0.9967609,0.00018623013,0.0003305081,0.00008729717,0.00028450147,0.0023505515],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0039632353,0.0001893611,0.0002742273,0.00022049787,0.0009624048,0.000047026148,0.00022996227,0.00046477173,0.0026092522],"category_scores_gemma":[0.0016329731,0.00018493363,0.00007086201,0.00028101238,0.00009538216,0.00025180646,0.000024077633,0.0032288004,0.00016583002],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016224605,0.0002761854,0.56369585,0.00007968207,0.00041543713,0.00047787608,0.005803721,0.0000021558635,0.0019146998,0.0006502475,0.07938452,0.3471374],"study_design_scores_gemma":[0.0036722675,0.00017552634,0.12989748,0.000062925,0.000056689027,0.0016523005,0.00042590525,0.002723155,0.011550919,0.0006068667,0.84860116,0.0005747868],"about_ca_topic_score_codex":0.010813317,"about_ca_topic_score_gemma":0.032481175,"teacher_disagreement_score":0.76921666,"about_ca_system_score_codex":0.00093087164,"about_ca_system_score_gemma":0.0025286519,"threshold_uncertainty_score":0.99907076},"labels":[],"label_agreement":null},{"id":"W2113127208","doi":"10.1124/jpet.108.137497","title":"p38 Mitogen-Activated Protein Kinase-Dependent Tumor Necrosis Factor-α-Converting Enzyme Is Important for Liver Injury in Hepatotoxic Interaction between Lipopolysaccharide and Ranitidine","year":2008,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Tumor necrosis factor alpha; Liver injury; Lipopolysaccharide; Pharmacology; p38 mitogen-activated protein kinases; Protein kinase A; Endocrinology; Internal medicine; Medicine; Kinase; Chemistry; Biochemistry","score_opus":0.12913886585422168,"score_gpt":0.4111122519771355,"score_spread":0.28197338612291384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2113127208","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99458635,0.0021346624,0.00006172846,0.00046994854,0.0015394068,0.0010789866,0.00007812944,0.000032787713,0.000017982433],"genre_scores_gemma":[0.99514717,0.0012931828,0.00013411646,0.0026708713,0.00052610994,0.00010743784,0.000004845217,0.000044127402,0.00007212433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974852,0.0004921538,0.0010085634,0.00034050003,0.00018899528,0.0004845514],"domain_scores_gemma":[0.99852496,0.00027848498,0.0007650076,0.000079062345,0.00013147513,0.00022099727],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00070842955,0.0003720973,0.0005990734,0.00033789568,0.00046920648,0.000026709211,0.00017641012,0.00040062334,0.0003421918],"category_scores_gemma":[0.000021764341,0.0003581705,0.00015545006,0.00014420711,0.0002622298,0.000496158,0.00008202192,0.0012944102,0.0000046440596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037575401,0.0004813169,0.013817563,0.00006258317,0.0004600846,0.00009854328,0.0044592074,0.0000045729776,0.9724495,0.000018009187,0.000114415256,0.004276709],"study_design_scores_gemma":[0.005274124,0.0010413696,0.0007743153,0.000043575652,0.00017627145,0.00038754533,0.00051563245,0.001076797,0.9846966,0.00010696802,0.0055603725,0.00034640334],"about_ca_topic_score_codex":0.000078387515,"about_ca_topic_score_gemma":0.0000047300387,"teacher_disagreement_score":0.013043248,"about_ca_system_score_codex":0.00030208266,"about_ca_system_score_gemma":0.00014505771,"threshold_uncertainty_score":0.99988705},"labels":[],"label_agreement":null},{"id":"W2113614979","doi":"10.1111/j.1365-2885.2009.01080.x","title":"The role of para‐aminophenol in acetaminophen‐induced methemoglobinemia in dogs and cats","year":2009,"lang":"en","type":"article","venue":"Journal of Veterinary Pharmacology and Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Toronto; University of Prince Edward Island","funders":"Canadian Institutes of Health Research","keywords":"Methemoglobinemia; Methemoglobin; CATS; Heinz body; Acetaminophen; Metabolite; Pharmacology; Toxicity; Chemistry; Medicine; Internal medicine; Hemoglobin; Biochemistry","score_opus":0.11964093947960878,"score_gpt":0.4329222436755453,"score_spread":0.3132813041959365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2113614979","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907157,0.0063798474,0.000008467871,0.0013586149,0.00069036754,0.0003523166,0.0000045686797,0.000008409218,0.00048169965],"genre_scores_gemma":[0.9922887,0.006294801,0.00011286844,0.0011102968,0.00014465452,0.000010993097,5.9107737e-7,0.000011795814,0.000025297937],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975559,0.0009955401,0.0007489536,0.00018656746,0.00013040223,0.00038261586],"domain_scores_gemma":[0.9985701,0.0006571027,0.0004625363,0.000101042984,0.00008711292,0.00012209309],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017819018,0.00022945648,0.00045475687,0.00025684026,0.00018310409,0.000014687348,0.00025716284,0.0004025569,0.000029876928],"category_scores_gemma":[0.000021818667,0.00018031719,0.00007287085,0.0002643718,0.00024661626,0.00019180257,0.000058394256,0.0013188012,0.0000013173639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023548002,0.0003889828,0.007665179,0.00002580522,0.00014019551,0.00011648562,0.0017374251,0.00004766259,0.80129004,0.0003293361,0.000010122973,0.18589397],"study_design_scores_gemma":[0.015375037,0.009054791,0.1529949,0.00013546398,0.00065323466,0.00284391,0.0017805246,0.004988845,0.6950169,0.026742801,0.08962094,0.0007926623],"about_ca_topic_score_codex":0.000015341158,"about_ca_topic_score_gemma":0.000013416714,"teacher_disagreement_score":0.1851013,"about_ca_system_score_codex":0.00007525157,"about_ca_system_score_gemma":0.00009086854,"threshold_uncertainty_score":0.73531216},"labels":[],"label_agreement":null},{"id":"W2114653864","doi":"10.4021/gr2010.06.210w","title":"Uncommon Cause of Acute Drug-induced Liver Injury Following Mammoplasty","year":2010,"lang":"en","type":"article","venue":"Gastroenterology Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Liver injury; Jaundice; Drug; Antimicrobial; Liver enzyme; Gastroenterology; Internal medicine; Surgery; Pharmacology; Microbiology","score_opus":0.18185591593244743,"score_gpt":0.48825040321186775,"score_spread":0.3063944872794203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114653864","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931454,0.000014934469,0.000041930416,0.00092661654,0.0032448112,0.00075869,0.00008509205,0.0000973686,0.0016851324],"genre_scores_gemma":[0.9980905,0.000061127415,0.00021503208,0.000466875,0.00035525247,0.00016707968,0.000025490279,0.0000423517,0.0005762913],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9948975,0.0021935138,0.0005463128,0.0005728088,0.00048718994,0.0013027097],"domain_scores_gemma":[0.99810094,0.0004956551,0.00016914072,0.0005432453,0.00029572274,0.0003952821],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0042740544,0.0002905158,0.0004856914,0.0005970198,0.00057039736,0.000026312795,0.00069355714,0.0007402797,0.00068951043],"category_scores_gemma":[0.0001891996,0.0002910033,0.00025072586,0.00046473887,0.00053206674,0.0002360953,0.0004469615,0.005611676,0.00032419496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018601102,0.00047610173,0.35000092,0.000046091383,0.0005813491,0.00021026422,0.0006280951,0.000004954346,0.6372657,0.0002758116,0.0022624168,0.0063881753],"study_design_scores_gemma":[0.0050898846,0.0019298359,0.11414225,0.000047524845,0.00040638237,0.00036773636,0.00026662886,0.0012401878,0.8603927,0.0010103692,0.014641502,0.00046503445],"about_ca_topic_score_codex":0.00025433404,"about_ca_topic_score_gemma":0.0012985707,"teacher_disagreement_score":0.23585868,"about_ca_system_score_codex":0.000088404115,"about_ca_system_score_gemma":0.00014772921,"threshold_uncertainty_score":0.9999542},"labels":[],"label_agreement":null},{"id":"W2115681278","doi":"10.1002/hep.22798","title":"Hepatitis C, alcohol abuse, and unintentional overdoses are risk factors for acetaminophen-related hepatotoxicity #","year":2009,"lang":"en","type":"letter","venue":"Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Acetaminophen; Internal medicine; Odds ratio; Liver disease; Hepatitis C; Liver injury; Alcohol abuse; Alcoholic hepatitis; Hepatitis C virus; Risk factor; Alcoholic liver disease; Gastroenterology; Cirrhosis; Psychiatry; Immunology; Anesthesia; Virus","score_opus":0.11952891845822136,"score_gpt":0.3832968709991246,"score_spread":0.26376795254090324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115681278","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93032485,0.0010572041,0.00042003457,0.054616556,0.0053347484,0.0031398255,0.0032570085,0.0005634754,0.0012863013],"genre_scores_gemma":[0.6765973,0.008130762,0.00046975532,0.30251625,0.0026780379,0.00085270905,0.0030913318,0.00026417107,0.0053997044],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9933667,0.0020297314,0.0012073966,0.0015189439,0.00038657457,0.0014906112],"domain_scores_gemma":[0.99538803,0.0018919614,0.0014337323,0.0005626904,0.0003801797,0.00034342482],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0008422105,0.0011813712,0.0016826378,0.0006263342,0.0011845124,0.00008236097,0.00058166654,0.007061455,0.0010152466],"category_scores_gemma":[0.00057490735,0.0012092442,0.0006357109,0.00038783348,0.0007745925,0.00027282344,0.00013636208,0.0075713303,0.00016314242],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034693166,0.00037196264,0.47546348,0.0005283571,0.0014765379,0.00054001546,0.0007196364,0.00002687088,0.0006604863,0.0008207231,0.51456004,0.0044849617],"study_design_scores_gemma":[0.0032592718,0.0005220053,0.019530216,0.00010484497,0.0011065848,0.00035911906,0.000054623935,0.007693226,0.004634196,0.0069030654,0.95431715,0.0015157161],"about_ca_topic_score_codex":0.0010619991,"about_ca_topic_score_gemma":0.00055386993,"teacher_disagreement_score":0.45593327,"about_ca_system_score_codex":0.0004057386,"about_ca_system_score_gemma":0.00022614951,"threshold_uncertainty_score":0.99989796},"labels":[],"label_agreement":null},{"id":"W2120113397","doi":"10.1517/14740338.2014.947958","title":"Characteristics associated with drug-induced liver injury from interferon beta in multiple sclerosis patients","year":2014,"lang":"en","type":"article","venue":"Expert Opinion on Drug Safety","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Western University; University of Manitoba; Child and Family Research Institute; Dalhousie University; BC Children's Hospital; University of British Columbia; University of British Columbia Hospital","funders":"Canadian Institutes of Health Research; London Health Sciences Centre","keywords":"Medicine; Hazard ratio; Internal medicine; Cohort; Retrospective cohort study; Multiple sclerosis; Liver injury; Drug; Proportional hazards model; Adverse effect; Confidence interval; Pharmacology; Immunology","score_opus":0.11568749489911455,"score_gpt":0.3493558357500897,"score_spread":0.23366834085097515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120113397","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99276817,0.0000618466,0.00009407167,0.0007978398,0.0037324168,0.00087560056,0.000334681,0.00018985136,0.0011454945],"genre_scores_gemma":[0.9951046,0.00069740554,0.000060564253,0.0026072962,0.0005046762,0.00015007325,0.000688571,0.000065089196,0.00012169385],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9961299,0.0016046107,0.0006618517,0.00067433284,0.00034424113,0.00058508094],"domain_scores_gemma":[0.9978616,0.0009944211,0.0003709275,0.00037424613,0.00014461916,0.0002541822],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009311533,0.00045455454,0.00053764397,0.00022309323,0.00042160446,0.00004035049,0.00036140264,0.00051389367,0.0002893345],"category_scores_gemma":[0.00032858655,0.00042642048,0.000113868504,0.000322762,0.0001124919,0.000267169,0.00012843581,0.0013954488,0.00022299004],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015318362,0.007926819,0.36013582,0.00007459804,0.0005752243,0.000013951431,0.022490924,0.00021103796,0.03609388,0.00054640643,0.012146636,0.5444663],"study_design_scores_gemma":[0.01138181,0.0010689868,0.6910794,0.00089490187,0.0000294728,8.757462e-7,0.00027611858,0.011868782,0.12846881,0.000080012614,0.15343404,0.0014168352],"about_ca_topic_score_codex":0.00067494635,"about_ca_topic_score_gemma":0.00039086063,"teacher_disagreement_score":0.5430495,"about_ca_system_score_codex":0.00046509763,"about_ca_system_score_gemma":0.000056890472,"threshold_uncertainty_score":0.99981874},"labels":[],"label_agreement":null},{"id":"W2121865715","doi":"10.1081/clt-120028751","title":"<i>N</i>‐Acetylcysteine for the Treatment of Clove Oil Induced Fulminant Hepatic Failure: Case Report and Review of the Literature","year":2004,"lang":"en","type":"article","venue":"Journal of Toxicology Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children; Queen's University","funders":"","keywords":"Fulminant hepatic failure; Acetylcysteine; Fulminant; Medicine; Toxicity; Acetaminophen; Anesthesia; Hepatic function; Surgery; Gastroenterology; Internal medicine; Liver transplantation; Chemistry","score_opus":0.1514019746689768,"score_gpt":0.47346799416296814,"score_spread":0.32206601949399133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121865715","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94964427,0.019751538,0.00009590824,0.023679774,0.005182649,0.0014221094,0.00007713634,0.000013091501,0.00013352603],"genre_scores_gemma":[0.94609815,0.046778154,0.00076026516,0.004956242,0.0009537363,0.00013992615,0.000004927615,0.00003332338,0.00027526892],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.993555,0.0020821556,0.0031908967,0.000416708,0.00025211592,0.00050308544],"domain_scores_gemma":[0.98956573,0.0052751624,0.0035533211,0.00058508094,0.00075297273,0.0002677299],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00546807,0.0003992286,0.0016952803,0.00016122939,0.00035675924,0.000012458657,0.00051763543,0.0013892407,0.00008974679],"category_scores_gemma":[0.0035598504,0.00022535713,0.0010153858,0.00050879596,0.0010039991,0.00013052396,0.00011953243,0.0016909402,0.0000027958772],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013253988,0.02869926,0.017227909,0.015005578,0.011597586,0.037014462,0.0077271857,0.0009560149,0.4212838,0.0062194215,0.00945411,0.43156067],"study_design_scores_gemma":[0.032383673,0.03978231,0.004540439,0.004675054,0.007276895,0.25163198,0.0006138272,0.00022765079,0.33880797,0.004756182,0.31430942,0.0009946092],"about_ca_topic_score_codex":0.00002149527,"about_ca_topic_score_gemma":0.0002702315,"teacher_disagreement_score":0.43056604,"about_ca_system_score_codex":0.00023680743,"about_ca_system_score_gemma":0.0007648643,"threshold_uncertainty_score":0.99990714},"labels":[],"label_agreement":null},{"id":"W2122421829","doi":"10.1684/epd.2009.0274","title":"Acetaminophen toxicity with concomitant use of carbamazepine","year":2009,"lang":"en","type":"article","venue":"Epileptic Disorders","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta Hospital","funders":"","keywords":"Carbamazepine; Toxicity; Concomitant; Acetaminophen; Medicine; Anesthesia; Pharmacology; Epilepsy; Internal medicine; Psychiatry","score_opus":0.1002165849004145,"score_gpt":0.3721894830940444,"score_spread":0.2719728981936299,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122421829","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98668253,0.000110953144,0.0015951655,0.0016221638,0.0004140976,0.000742147,0.000034422406,0.00012930919,0.00866923],"genre_scores_gemma":[0.99656516,0.00017194432,0.0007301629,0.0017325528,0.00008394717,0.000032171243,0.00001654348,0.000020419326,0.00064710283],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982769,0.0003377624,0.00039236151,0.00033471952,0.00020992168,0.0004483576],"domain_scores_gemma":[0.9989342,0.000288165,0.00021513969,0.00028867734,0.00008549095,0.00018834062],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004000466,0.00026664088,0.000392898,0.00012385455,0.00018608295,0.00002059313,0.00021077415,0.00031550616,0.0005248366],"category_scores_gemma":[0.00013331303,0.00023523952,0.000114234375,0.00033890165,0.00026338297,0.0002657134,0.000029629484,0.00067870267,0.000051681243],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0042844294,0.004318206,0.079110906,0.00028544228,0.0009601032,0.000079475634,0.0054022637,0.017422602,0.34425095,0.015049717,0.0058777127,0.5229582],"study_design_scores_gemma":[0.017251028,0.008407156,0.22168791,0.00029043565,0.0010979779,0.000096012765,0.0013342052,0.024257148,0.2820824,0.011891618,0.42870173,0.0029023853],"about_ca_topic_score_codex":0.00012858384,"about_ca_topic_score_gemma":0.00020919298,"teacher_disagreement_score":0.52005583,"about_ca_system_score_codex":0.00006800058,"about_ca_system_score_gemma":0.0000821147,"threshold_uncertainty_score":0.95927894},"labels":[],"label_agreement":null},{"id":"W2128664046","doi":"10.1124/dmd.113.056622","title":"Paradoxical Attenuation of Autoimmune Hepatitis by Oral Isoniazid in Wild-Type and N-Acetyltransferase–Deficient Mice","year":2014,"lang":"en","type":"article","venue":"Drug Metabolism and Disposition","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Liver injury; Immune system; Immunology; Autoimmune hepatitis; Medicine; Hepatitis; Isoniazid; Internal medicine; Endocrinology; Pharmacology; Pathology","score_opus":0.029459938512550972,"score_gpt":0.33643517730323114,"score_spread":0.30697523879068017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128664046","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948652,0.0016676746,0.0014430028,0.0007404972,0.00050350453,0.0003679436,0.00008142526,0.00003510384,0.0002956867],"genre_scores_gemma":[0.99755496,0.0015175808,0.00013321657,0.000475052,0.00006477722,0.000033571476,0.00013646072,0.000013008064,0.000071379895],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99835616,0.0006158222,0.00035669096,0.00028978998,0.0001371504,0.00024436275],"domain_scores_gemma":[0.9994891,0.00013849513,0.00009828279,0.00010006081,0.00006702551,0.00010699166],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00081590784,0.00017831367,0.0003288402,0.00012321828,0.00017557341,0.000022671227,0.000067492474,0.00023320813,0.000047058256],"category_scores_gemma":[0.000043457218,0.00017978958,0.000038306796,0.00028333545,0.00014904457,0.00022157172,0.000026285828,0.00037932303,0.000009704513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00085844373,0.0007190856,0.02590777,0.00020332537,0.000064882464,0.000003526979,0.0036103346,0.00022897648,0.7917306,0.011545258,0.0005127469,0.1646151],"study_design_scores_gemma":[0.008431113,0.0003962316,0.43103674,0.00014071826,0.0005402164,0.00006644823,0.0003544104,0.056197196,0.45279315,0.0034581025,0.045593403,0.0009922718],"about_ca_topic_score_codex":0.00063945353,"about_ca_topic_score_gemma":0.00011734486,"teacher_disagreement_score":0.40512896,"about_ca_system_score_codex":0.000021403643,"about_ca_system_score_gemma":0.000019949814,"threshold_uncertainty_score":0.7331606},"labels":[],"label_agreement":null},{"id":"W2128784858","doi":"10.1016/j.taap.2008.01.002","title":"Role of hydrazine in isoniazid-induced hepatotoxicity in a hepatocyte inflammation model","year":2008,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":168,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Isoniazid; Metabolite; Hydrazine (antidepressant); Hepatocyte; Pharmacology; Cytotoxicity; Chemistry; Toxicity; Oxidative stress; Inflammation; Reactive oxygen species; Biochemistry; Biology; Immunology; Medicine; Tuberculosis; Pathology; Organic chemistry","score_opus":0.08636317606078663,"score_gpt":0.37160463527993426,"score_spread":0.2852414592191476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128784858","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888571,0.00023782732,0.000073751966,0.0005040792,0.00040306742,0.0017681834,0.000027216935,0.00011230769,0.008016464],"genre_scores_gemma":[0.9967222,0.0006578354,0.00027885157,0.0012505746,0.00018389216,0.0007608173,0.000018998726,0.000041397685,0.00008540212],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99624836,0.00076568377,0.0011202925,0.00074859883,0.00018793948,0.00092910166],"domain_scores_gemma":[0.99855006,0.00049363094,0.0004004717,0.00022282066,0.00007084429,0.00026220415],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.001337774,0.0004768506,0.00095574564,0.00080145727,0.0002873803,0.000005824863,0.0003482648,0.0013770431,0.0003977747],"category_scores_gemma":[0.000057949,0.0005369219,0.00009973135,0.0007697293,0.00055034633,0.00022826204,0.00020909826,0.0020713827,0.000059389666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018760592,0.0008317207,0.031897414,0.00008837774,0.0000772169,0.00006406406,0.002874448,0.008040409,0.93905073,0.0036305662,0.000081822865,0.011487171],"study_design_scores_gemma":[0.007248471,0.00029303468,0.030587405,0.000017175524,0.00006996334,0.0001289007,0.00016384952,0.10144308,0.8528935,0.005116978,0.0014844654,0.000553187],"about_ca_topic_score_codex":0.00013816774,"about_ca_topic_score_gemma":0.0006877057,"teacher_disagreement_score":0.09340268,"about_ca_system_score_codex":0.00024146505,"about_ca_system_score_gemma":0.00030790566,"threshold_uncertainty_score":0.99991935},"labels":[],"label_agreement":null},{"id":"W2128926183","doi":"10.3109/15563650.2011.597031","title":"Acetaminophen psi parameter: A useful tool to quantify hepatotoxicity risk in acute acetaminophen overdose","year":2011,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Faculty of Medicine Siriraj Hospital, Mahidol University","keywords":"Acetaminophen; Medicine; Interquartile range; acetaminophen overdose; Context (archaeology); Univariate analysis; Population; Regimen; Acetylcysteine; Anesthesia; Ingestion; Internal medicine; Multivariate analysis","score_opus":0.3282774078610636,"score_gpt":0.4818181105690892,"score_spread":0.1535407027080256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128926183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9854685,0.00010289043,0.0008599973,0.00066925347,0.005370102,0.0026578996,0.00019708026,0.00035690708,0.0043173437],"genre_scores_gemma":[0.9845435,0.0006666691,0.0033218858,0.009246331,0.0005866773,0.0006425261,0.000026504433,0.000094295945,0.0008716058],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.98913413,0.004770282,0.0023588545,0.0016829544,0.00033792458,0.0017158783],"domain_scores_gemma":[0.99397296,0.0030844794,0.00072886987,0.0010799064,0.00017721148,0.000956582],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.005746026,0.00077432086,0.001668405,0.0005065228,0.0004552094,0.000047658512,0.0011974032,0.002922238,0.0025891382],"category_scores_gemma":[0.003576114,0.00078428996,0.0006195995,0.0010155528,0.0007342554,0.00039651207,0.0006931528,0.0048278207,0.0029890356],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00478343,0.004475748,0.89242595,0.00006301965,0.0008600005,0.00062658376,0.002222892,0.00010223952,0.010279178,0.002561475,0.00241498,0.07918447],"study_design_scores_gemma":[0.007847295,0.0036453363,0.8275865,0.000045422836,0.0006755693,0.00012775912,0.00015489862,0.0032581033,0.04797997,0.008747918,0.09828195,0.0016493007],"about_ca_topic_score_codex":0.00031490813,"about_ca_topic_score_gemma":0.00056825724,"teacher_disagreement_score":0.09586697,"about_ca_system_score_codex":0.00037540085,"about_ca_system_score_gemma":0.00028986746,"threshold_uncertainty_score":0.9994608},"labels":[],"label_agreement":null},{"id":"W2130432764","doi":"10.1016/j.annemergmed.2005.04.004","title":"A Risk Quantification Instrument for Acute Acetaminophen Overdose Patients Treated With N-Acetylcysteine","year":2005,"lang":"en","type":"article","venue":"Annals of Emergency Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":78,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Toronto; Queen's University","funders":"","keywords":"Medicine; Acetaminophen; Acetylcysteine; acetaminophen overdose; Confidence interval; Regimen; Internal medicine; Toxicity; Anesthesia; Gastroenterology","score_opus":0.25745798784603025,"score_gpt":0.47821439348368383,"score_spread":0.22075640563765359,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130432764","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913066,0.00034418507,0.00056698715,0.0032835784,0.000952064,0.0013521276,0.00021391945,0.00006273806,0.001917799],"genre_scores_gemma":[0.9941613,0.0028072973,0.00017537181,0.00041070866,0.0004591736,0.00020798523,0.00024033252,0.000027027316,0.0015108164],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981278,0.00023762563,0.0006957041,0.00033159467,0.00024296681,0.00036427687],"domain_scores_gemma":[0.99838084,0.00010575217,0.00056970527,0.00025676095,0.00050696137,0.00017996474],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008037603,0.00024898202,0.000391959,0.00016079957,0.00023027285,0.0000018443402,0.00017931749,0.00023366553,0.0011662205],"category_scores_gemma":[0.00019508466,0.00019205944,0.000106200285,0.00036355303,0.00011266511,0.00018853886,0.000023450564,0.0003202462,0.00003273575],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01256127,0.005124339,0.3409478,0.00064603915,0.0051871645,0.000004715591,0.0066139405,0.0014747811,0.2787184,0.0023645917,0.087636486,0.25872046],"study_design_scores_gemma":[0.012685646,0.007070793,0.058134418,0.00016352301,0.0017322403,0.00000419196,0.00021339569,0.0064456877,0.56327,0.00050276564,0.3490538,0.00072355464],"about_ca_topic_score_codex":0.0001789949,"about_ca_topic_score_gemma":0.00008178107,"teacher_disagreement_score":0.28455156,"about_ca_system_score_codex":0.000033422893,"about_ca_system_score_gemma":0.00003284455,"threshold_uncertainty_score":0.99974686},"labels":[],"label_agreement":null},{"id":"W2132317310","doi":"10.1017/s1481803500015153","title":"Emergency department visits for acetaminophen overdose: a Canadian population-based epidemiologic study (1997–2002)","year":2007,"lang":"en","type":"article","venue":"Canadian Journal of Emergency Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Acetaminophen; Emergency department; Incidence (geometry); acetaminophen overdose; Epidemiology; Drug overdose; Population; Emergency medicine; Demography; Poison control; Environmental health; Psychiatry; Internal medicine; Anesthesia","score_opus":0.2987097261812234,"score_gpt":0.4854648487282746,"score_spread":0.18675512254705123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132317310","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9594329,0.0025821563,0.0015528575,0.0040100543,0.027627802,0.0019340565,0.00018895924,0.000024168157,0.0026470176],"genre_scores_gemma":[0.9952383,0.00013685667,0.00013339931,0.0011043738,0.0023451191,0.00004438029,0.00007687037,0.000036927984,0.00088375853],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.99601156,0.00056552375,0.0017295971,0.00033586574,0.00026624117,0.0010911974],"domain_scores_gemma":[0.99548596,0.0003464426,0.00073462416,0.0002471051,0.00056750287,0.0026183578],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0064877174,0.0003594391,0.00064240495,0.00093045924,0.0008112567,0.000004670711,0.00043043526,0.0004292145,0.013050042],"category_scores_gemma":[0.0020212333,0.0003182603,0.00023852897,0.0006753887,0.00005764554,0.0001536826,0.000008629151,0.00092678884,0.000043204513],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036896285,0.0002712532,0.86670756,0.00011210267,0.00053293747,0.00031684697,0.0018433973,0.0015595075,0.00094389886,0.00048187267,0.11396263,0.012899018],"study_design_scores_gemma":[0.0040104603,0.0027699443,0.48187503,0.00008351501,0.0007129159,0.00003197567,0.0010216315,0.0009370394,0.0005564871,0.0018611273,0.5054904,0.0006494236],"about_ca_topic_score_codex":0.19362049,"about_ca_topic_score_gemma":0.8464237,"teacher_disagreement_score":0.6528032,"about_ca_system_score_codex":0.0010182341,"about_ca_system_score_gemma":0.0013256404,"threshold_uncertainty_score":0.9999269},"labels":[],"label_agreement":null},{"id":"W2135880847","doi":"10.1186/1472-6904-12-11","title":"Population prevalence of high dose paracetamol in dispensed paracetamol/opioid prescription combinations: an observational study","year":2012,"lang":"en","type":"article","venue":"BMC Clinical Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Capital District Health Authority; Dalhousie University","funders":"College of Pharmacy, Dalhousie University; Faculty of Medicine, Dalhousie University; Canadian Institutes of Health Research; Dalhousie University; Department of Health, Western Cape Government; Nova Scotia Health Research Foundation; Nova Scotia Department of Health and Wellness; Canadian Health Services Research Foundation","keywords":"Medicine; Observational study; Medical prescription; Acetaminophen; Population; Pharmacoepidemiology; Pharmacology; Opioid; Internal medicine; Intensive care medicine; Emergency medicine; Environmental health","score_opus":0.5608768438244115,"score_gpt":0.5632974580941309,"score_spread":0.002420614269719401,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135880847","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893766,0.00020758578,0.00019859454,0.00023644685,0.0065566935,0.0031031438,0.0000742293,0.00011242559,0.00013428384],"genre_scores_gemma":[0.9962431,0.00017715177,0.00048632102,0.0010065725,0.0010098652,0.0006129551,0.00015263035,0.000033445347,0.000277925],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9903928,0.0061603286,0.0018235099,0.0006124215,0.00034898755,0.0006619599],"domain_scores_gemma":[0.99611884,0.0021954295,0.00076385733,0.00033494024,0.00021294742,0.00037398978],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00586324,0.00033467653,0.00070393045,0.00027227803,0.00025502086,0.000015251379,0.00042450955,0.0007261514,0.001463001],"category_scores_gemma":[0.0007398597,0.00035289416,0.00017393884,0.00050564954,0.0002694149,0.0009978393,0.0001351872,0.001501525,0.00011580107],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017139086,0.0146123655,0.9692889,0.00019570123,0.000111176494,0.0000049527193,0.00070783077,0.001458681,0.0062239277,0.0014603649,0.000364625,0.0038575802],"study_design_scores_gemma":[0.008731435,0.00083464204,0.977399,0.000017637405,0.00035080328,0.000007442685,0.00011998554,0.0071799145,0.0023131042,0.0017104441,0.0009984137,0.00033716508],"about_ca_topic_score_codex":0.00038961146,"about_ca_topic_score_gemma":0.00029775721,"teacher_disagreement_score":0.013777724,"about_ca_system_score_codex":0.00017412237,"about_ca_system_score_gemma":0.00014526967,"threshold_uncertainty_score":0.9998923},"labels":[],"label_agreement":null},{"id":"W2136257038","doi":"10.1503/cmaj.111338","title":"Acetaminophen overdose in children: Figure 1:","year":2012,"lang":"en","type":"article","venue":"Canadian Medical Association Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre","funders":"","keywords":"Acetaminophen; Emergency department; Medicine; Gestation; Drug overdose; Medical emergency; Emergency medicine; Pregnancy; Pediatrics; Anesthesia; Poison control; Nursing","score_opus":0.043321960730280606,"score_gpt":0.3575190157545271,"score_spread":0.3141970550242465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136257038","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9743203,0.0004714683,0.000018056475,0.010290018,0.0028211481,0.00021522533,0.000030649222,0.00002451744,0.011808597],"genre_scores_gemma":[0.9795181,0.00016537863,0.000024154167,0.016381536,0.0032016304,0.000013655111,0.000012586558,0.000013695922,0.00066924],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.997356,0.00075191155,0.00037396888,0.00011963657,0.0005524559,0.0008460182],"domain_scores_gemma":[0.9975122,0.00017327853,0.00017268206,0.000067458954,0.00009541251,0.0019789215],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0038357978,0.00013630712,0.00019043799,0.00023710768,0.00035735467,0.000035335564,0.00021182642,0.0011197856,0.012610094],"category_scores_gemma":[0.0010382164,0.00013830392,0.00008363674,0.0002943921,0.00003497716,0.00029996177,0.000017221066,0.0032133567,0.00088558707],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011463061,0.000095724456,0.9279326,0.0000036237418,0.000092174414,0.000042969685,0.0005915273,0.000025229061,0.00008793737,0.00036588166,0.027463276,0.04328756],"study_design_scores_gemma":[0.0013557364,0.000024406336,0.43589973,0.000017974777,0.000026918124,0.000365189,0.00010839314,0.0002783141,0.00037320037,0.00024627385,0.56110823,0.00019563593],"about_ca_topic_score_codex":0.0017775816,"about_ca_topic_score_gemma":0.0061458116,"teacher_disagreement_score":0.533645,"about_ca_system_score_codex":0.0014455937,"about_ca_system_score_gemma":0.00095537613,"threshold_uncertainty_score":0.99989235},"labels":[],"label_agreement":null},{"id":"W2136381643","doi":"10.1080/03602530500205200","title":"The Molecular Toxicology of Acetaminophen","year":2005,"lang":"en","type":"review","venue":"Drug Metabolism Reviews","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Acetaminophen; Toxicity; Chemistry; Pharmacology; Electrophile; Enzyme; Mechanism (biology); Toxicology; Biochemistry; Medicine; Biology; Catalysis; Organic chemistry","score_opus":0.21788061852220367,"score_gpt":0.4863180587757896,"score_spread":0.26843744025358596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136381643","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000026590185,0.9838753,0.00003912171,0.00024909695,0.0041492777,0.004679967,0.0001077264,0.00007941864,0.00679355],"genre_scores_gemma":[0.00001402693,0.99242514,0.00026011336,0.0007171827,0.0011996628,0.0016199081,0.00006689215,0.000106536114,0.0035905566],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9875893,0.007853262,0.0025720422,0.0007610892,0.00032087433,0.0009034033],"domain_scores_gemma":[0.99506384,0.0011495678,0.0022070664,0.0011370195,0.00014063963,0.00030187325],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0061468845,0.0009802976,0.0044660377,0.00027813314,0.0005378346,0.000044125103,0.0015598566,0.0013713858,0.0006101615],"category_scores_gemma":[0.00064312964,0.00063167274,0.0019759724,0.0008690532,0.0004754762,0.00013419394,0.00032662338,0.003213982,0.0015298799],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014103933,0.00013589856,3.1477427e-7,0.00515941,0.00038449003,0.000009600746,0.000137976,0.0000030515307,0.00008746315,0.0057241623,0.0044368505,0.9839067],"study_design_scores_gemma":[0.0003400884,0.000018897937,0.0000011010482,0.0011964419,0.0033660943,0.000058146896,0.0000104866185,0.000009232413,0.00043524086,0.0002424801,0.9937632,0.00055857626],"about_ca_topic_score_codex":0.00001613873,"about_ca_topic_score_gemma":0.000027433583,"teacher_disagreement_score":0.98932636,"about_ca_system_score_codex":0.00014142616,"about_ca_system_score_gemma":0.00037603415,"threshold_uncertainty_score":0.999925},"labels":[],"label_agreement":null},{"id":"W2136956219","doi":"10.1016/j.taap.2014.01.004","title":"Neutrophil activation during acetaminophen hepatotoxicity and repair in mice and humans","year":2014,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":169,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; McGill University; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; National Center for Research Resources; National Institute of General Medical Sciences","keywords":"Acetaminophen; Pharmacology; Medicine; Chemistry","score_opus":0.050686928712269735,"score_gpt":0.3513040897529719,"score_spread":0.30061716104070213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136956219","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993304,0.00021873848,0.00006002606,0.0014788698,0.00056810974,0.0011518433,0.000018543624,0.00024500993,0.0029548507],"genre_scores_gemma":[0.9934844,0.000648944,0.00021321276,0.004577806,0.00040741623,0.00038933574,0.000012070284,0.000039261504,0.00022758388],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967175,0.00093500916,0.00055240496,0.00091076555,0.00010753497,0.0007767981],"domain_scores_gemma":[0.9985397,0.0007097004,0.000224512,0.00015400794,0.000039155148,0.00033293333],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012636556,0.0004467288,0.00063909235,0.00036067315,0.0007089466,0.000020143618,0.00016584137,0.0010426997,0.00026729712],"category_scores_gemma":[0.000057928624,0.0004866582,0.000055282893,0.0002699433,0.00074462674,0.00021194285,0.00027459714,0.0017156841,0.000025056514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012148034,0.0003538596,0.018255157,0.00026860094,0.00013517779,0.000020044632,0.0012386459,0.00017225572,0.96386373,0.0066003157,0.0002560612,0.007621338],"study_design_scores_gemma":[0.01233794,0.000603133,0.23244065,0.00003064392,0.00030757944,0.00021840364,0.00030471256,0.006123628,0.715631,0.0052704364,0.025619268,0.0011125824],"about_ca_topic_score_codex":0.000049948307,"about_ca_topic_score_gemma":0.00009522997,"teacher_disagreement_score":0.24823272,"about_ca_system_score_codex":0.00011158844,"about_ca_system_score_gemma":0.00004536566,"threshold_uncertainty_score":0.9997585},"labels":[],"label_agreement":null},{"id":"W2136959587","doi":"10.18433/j36g6x","title":"Hepatotoxic Botanicals - An Evidence-based Systematic Review","year":2013,"lang":"en","type":"review","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"University of Alberta","keywords":"Medicine; Cochrane Library; Traditional medicine; Adverse effect; Cirrhosis; Systematic review; Hepatotoxin; Drug; MEDLINE; Intensive care medicine; Pharmacology; Toxicity; Alternative medicine; Internal medicine; Pathology","score_opus":0.5734388595906567,"score_gpt":0.5870464740770834,"score_spread":0.013607614486426778,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136959587","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00013229027,0.98775166,0.00012127172,0.0011730908,0.0036536134,0.0065348023,0.000058445585,0.00013858489,0.00043625574],"genre_scores_gemma":[0.0008713417,0.9884127,0.00040872657,0.008016138,0.00141299,0.0006195527,0.000009614937,0.00010521378,0.00014373452],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.9783878,0.011561364,0.0052976455,0.0011114504,0.002078778,0.0015629999],"domain_scores_gemma":[0.9861775,0.0054558287,0.0047295755,0.0006473476,0.00081367505,0.002176048],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.018999008,0.0014212272,0.0060721836,0.00086698873,0.0009610364,0.00038316476,0.0038662462,0.0008540039,0.00542439],"category_scores_gemma":[0.003088477,0.00096827873,0.0023884724,0.0024595798,0.0012655659,0.0026247622,0.0002784754,0.0059920987,0.0010997574],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005821618,0.0007608404,0.000016828682,0.54652077,0.00055620767,0.00018870262,0.000034550463,0.00002172242,0.00043585416,0.00009097449,0.0018159279,0.4494994],"study_design_scores_gemma":[0.0008005696,0.00038327806,2.2137516e-7,0.28053173,0.010695893,0.00095619966,0.000012579109,0.0019256674,0.0012651841,0.00005619294,0.70251465,0.00085784565],"about_ca_topic_score_codex":0.000028945975,"about_ca_topic_score_gemma":0.000002310231,"teacher_disagreement_score":0.70069873,"about_ca_system_score_codex":0.0007234576,"about_ca_system_score_gemma":0.0027788451,"threshold_uncertainty_score":0.9998538},"labels":[],"label_agreement":null},{"id":"W2139618526","doi":"10.1139/cjpp-2012-0223","title":"Molecular cytotoxic mechanisms of chlorpromazine in isolated rat hepatocytes","year":2013,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Cytotoxicity; Glutathione; Chemistry; Metabolite; Hepatocyte; Pharmacology; Biochemistry; Mechanism of action; Chlorpromazine; Monooxygenase; Cytochrome P450; Metabolism; Enzyme; Biology; In vitro","score_opus":0.03897821818146017,"score_gpt":0.33148117395542714,"score_spread":0.29250295577396696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139618526","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99513,0.000745762,0.00021152504,0.001040263,0.0019472112,0.000572382,0.000019740064,0.000010517157,0.00032257184],"genre_scores_gemma":[0.99729735,0.00018967991,0.00010747146,0.002129143,0.00015174825,0.000047552712,0.000006842071,0.000021818336,0.00004839573],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974781,0.0008689311,0.0007281902,0.00025061707,0.00007508239,0.0005990476],"domain_scores_gemma":[0.99831915,0.0002599295,0.00044877132,0.00010765968,0.0002563043,0.000608181],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00068891316,0.00026031167,0.00062727253,0.0006050609,0.0001588156,0.0000090674575,0.0003094826,0.00063671113,0.005419046],"category_scores_gemma":[0.000059568916,0.00025166437,0.00012477851,0.00033122714,0.00044949184,0.0002368581,0.000035628425,0.0013562615,0.000052655778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024471432,0.00010136296,0.0024094533,0.00010166502,0.000179985,0.00015415355,0.00040151842,0.00056221214,0.99295735,0.0011757602,0.0005067418,0.0012050591],"study_design_scores_gemma":[0.002344243,0.0007088578,0.0036532732,0.00002720168,0.0001074672,0.0002615334,0.00007766305,0.002328021,0.96839744,0.01984099,0.002010076,0.00024320924],"about_ca_topic_score_codex":0.0013765652,"about_ca_topic_score_gemma":0.0008418532,"teacher_disagreement_score":0.02455991,"about_ca_system_score_codex":0.00008611183,"about_ca_system_score_gemma":0.0005415888,"threshold_uncertainty_score":0.99999356},"labels":[],"label_agreement":null},{"id":"W2140042090","doi":"10.1016/j.clpt.2003.12.008","title":"Use of population modeling to define rational monitoring of amiodarone hepatic effects*1","year":2004,"lang":"en","type":"article","venue":"Clinical Pharmacology & Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; Queen Elizabeth II Health Sciences Centre","funders":"","keywords":"Amiodarone; Medicine; Internal medicine; Albumin; Lactate dehydrogenase; Gastroenterology; NONMEM; Population; Bilirubin; Pharmacology; Endocrinology; Pharmacokinetics; Chemistry; Enzyme; Atrial fibrillation; Biochemistry","score_opus":0.3997537084719063,"score_gpt":0.5196891367941098,"score_spread":0.1199354283222035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2140042090","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9820482,0.00020547862,0.009451541,0.0019511969,0.005113356,0.0010751365,0.000033932298,0.00008854579,0.000032592186],"genre_scores_gemma":[0.9849977,0.0005129455,0.0054504853,0.008170061,0.0006845495,0.0000817586,0.000028796298,0.000040601055,0.000033115048],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99630934,0.001107262,0.0014510276,0.0004282475,0.00026876852,0.00043537852],"domain_scores_gemma":[0.9968787,0.0018439088,0.00047775928,0.00023842196,0.00031126663,0.00024993691],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014288859,0.00029505955,0.0007031017,0.0002243707,0.00020764829,0.00001046048,0.00027882963,0.0006693376,0.0000868993],"category_scores_gemma":[0.0001820257,0.00030416268,0.0002614837,0.00042696728,0.00023099789,0.00021433514,0.00010677531,0.0011572174,0.000050174174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021224527,0.0023465683,0.12632614,0.0002625044,0.0012450593,0.000014687227,0.0007016611,0.3383742,0.507202,0.0004183405,0.00013381641,0.020852564],"study_design_scores_gemma":[0.01043527,0.0026367719,0.074559204,0.00024264074,0.0029855573,0.000023265286,0.0000813198,0.08718882,0.8096416,0.005279379,0.005937977,0.0009882123],"about_ca_topic_score_codex":0.00011953473,"about_ca_topic_score_gemma":0.000013638746,"teacher_disagreement_score":0.30243957,"about_ca_system_score_codex":0.00015847417,"about_ca_system_score_gemma":0.00014150553,"threshold_uncertainty_score":0.99994105},"labels":[],"label_agreement":null},{"id":"W2141674087","doi":"10.1128/aac.01719-09","title":"Cysteamine, the Molecule Used To Treat Cystinosis, Potentiates the Antimalarial Efficacy of Artemisinin","year":2010,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Artemisinin; Plasmodium chabaudi; Malaria; Cystinosis; Parasitemia; Plasmodium falciparum; Dihydroartemisinin; Pharmacology; Artesunate; Medicine; Primaquine; Combination therapy; Cysteamine; Immunology; Biology; Internal medicine; Biochemistry; Cysteine; Cystine; Chloroquine","score_opus":0.061863644038269903,"score_gpt":0.3774787061599162,"score_spread":0.3156150621216463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141674087","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9872534,0.000014080886,0.00008578391,0.010250553,0.0008784787,0.0007869212,0.000047473506,0.000038482754,0.0006447772],"genre_scores_gemma":[0.99081665,0.00013186592,0.00009462176,0.008184741,0.00038278828,0.000018886449,0.000012704319,0.000025683483,0.00033205928],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99877214,0.00020621577,0.00030337775,0.00028064818,0.00012168115,0.00031594816],"domain_scores_gemma":[0.9992227,0.00020088816,0.00014782876,0.0002643007,0.000062361774,0.00010194003],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005204118,0.00022148743,0.00024402278,0.000053422675,0.00049305067,0.000051016505,0.0003340127,0.0002717013,0.0003295449],"category_scores_gemma":[0.00003976367,0.00013654424,0.000120459146,0.00021318656,0.00024547966,0.000060670754,0.00006237299,0.00062291016,0.000034158056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043388025,0.00034390038,0.008782368,0.000025749701,0.0001119152,0.0000039642755,0.0016593667,0.000034031058,0.9662238,0.00014625922,0.009605449,0.012629313],"study_design_scores_gemma":[0.0028955657,0.00012437698,0.04779819,0.00001909372,0.00010157597,0.000040012455,0.00004772356,0.00022650504,0.8827304,0.00005426134,0.06574546,0.00021682747],"about_ca_topic_score_codex":0.00013083826,"about_ca_topic_score_gemma":0.000043224114,"teacher_disagreement_score":0.0834934,"about_ca_system_score_codex":0.00000920143,"about_ca_system_score_gemma":0.00003323676,"threshold_uncertainty_score":0.5568113},"labels":[],"label_agreement":null},{"id":"W2143641481","doi":"10.1111/j.1365-2893.2005.00636.x","title":"Silymarin treatment of viral hepatitis: a systematic review","year":2005,"lang":"en","type":"review","venue":"Journal of Viral Hepatitis","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":189,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Milk Thistle; Silybum marianum; Medicine; Viral hepatitis; Viral load; Internal medicine; Hepatitis; Hepatitis B; Gastroenterology; Hepatitis C; Liver disease; Immunology; Virology; Pharmacology; Traditional medicine; Virus","score_opus":0.1469577002209933,"score_gpt":0.46104103941205554,"score_spread":0.31408333919106224,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2143641481","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00033232738,0.99266475,0.0000380322,0.000105560146,0.002106324,0.0033683332,0.00031134894,0.000036780548,0.0010365221],"genre_scores_gemma":[0.00068460946,0.9959892,0.00023027926,0.00043946397,0.0011940649,0.00032536997,0.000052732437,0.00008643916,0.0009978125],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9913027,0.0030746027,0.0040836004,0.00038129094,0.0005934918,0.0005643125],"domain_scores_gemma":[0.99288034,0.0007029858,0.005192528,0.00047709947,0.0003798923,0.00036716796],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0017607153,0.0008654666,0.006286819,0.00055256934,0.00020046189,0.000036330384,0.000653498,0.0010961874,0.0008096851],"category_scores_gemma":[0.0003256925,0.0006510558,0.0023894056,0.00045220772,0.00015925089,0.00035409708,0.00007768272,0.0015597304,0.00025200643],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039924304,0.00068983575,0.00010347169,0.4429795,0.0016101659,0.0002577154,0.00013766297,0.0000040080627,0.0000074066993,0.00009449207,0.0008234829,0.55325234],"study_design_scores_gemma":[0.00086766883,0.00172064,0.000011289349,0.26737356,0.011948627,0.001190462,0.000005170206,0.00003960353,0.00009909989,0.00008503436,0.71613914,0.0005197108],"about_ca_topic_score_codex":0.00040834828,"about_ca_topic_score_gemma":0.00022186532,"teacher_disagreement_score":0.71531564,"about_ca_system_score_codex":0.0012266088,"about_ca_system_score_gemma":0.0006987826,"threshold_uncertainty_score":0.9995941},"labels":[],"label_agreement":null},{"id":"W2146760773","doi":"10.1186/1476-5926-10-8","title":"Evaluation of the effects of a VEGFR-2 inhibitor compound on alanine aminotransferase gene expression and enzymatic activity in the rat liver","year":2011,"lang":"en","type":"article","venue":"Comparative Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Liver Lobe; Internal medicine; Caudate lobe; Endocrinology; Alanine aminotransferase; Gene expression; Immunohistochemistry; Enzyme assay; Alanine transaminase; Enzyme; Hepatectomy; Pathology; Gene; Biology; Biochemistry; Surgery","score_opus":0.28194386189635484,"score_gpt":0.42212508518720876,"score_spread":0.14018122329085392,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2146760773","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99637455,0.00038593565,0.00010357782,0.000074973555,0.0006181779,0.0015091163,0.000009754764,0.000009490602,0.0009144055],"genre_scores_gemma":[0.9994755,0.0000566282,0.000037476155,0.00020024911,0.00003326789,0.00018085736,0.0000026783966,0.000006283039,0.0000070862493],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9934188,0.0056319246,0.00029133869,0.00022093134,0.0002538447,0.00018316269],"domain_scores_gemma":[0.9981718,0.0012162668,0.00021139954,0.00021867803,0.00014254752,0.000039307513],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015432886,0.00017441533,0.0003768551,0.0000955611,0.00015471222,0.0000033706356,0.00019715098,0.00023663155,0.00006388069],"category_scores_gemma":[0.0001482505,0.00011157359,0.00006263152,0.00020270409,0.0003994576,0.00007880103,0.000049067432,0.0006054927,0.000006403523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009103224,0.0012727218,0.032584805,0.00023392044,0.00008727516,0.000011994754,0.022103613,0.000054340282,0.93888015,0.0007498868,0.0001619981,0.0029490013],"study_design_scores_gemma":[0.002064902,0.000416764,0.050274562,0.00006897004,0.00017348069,0.00002132689,0.000124451,0.007324394,0.9385256,0.00081250095,0.00009204268,0.00010097873],"about_ca_topic_score_codex":0.00010499717,"about_ca_topic_score_gemma":0.000247826,"teacher_disagreement_score":0.021979162,"about_ca_system_score_codex":0.000056146306,"about_ca_system_score_gemma":0.000081054844,"threshold_uncertainty_score":0.45498386},"labels":[],"label_agreement":null},{"id":"W2147665598","doi":"10.3109/15476910903501748","title":"Cytokine and autoantibody patterns in acute liver failure","year":2009,"lang":"en","type":"article","venue":"Journal of Immunotoxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research","keywords":"Autoantibody; Medicine; Acetaminophen; Immunology; Chemokine; Cytokine; Liver injury; Immune system; Viral hepatitis; Autoimmune hepatitis; Hepatitis; Antibody; Internal medicine; Pharmacology","score_opus":0.05532634919578098,"score_gpt":0.39595770667768593,"score_spread":0.34063135748190493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147665598","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937341,0.00068733125,0.00027575254,0.0033958843,0.0010216405,0.00033043115,0.000016583586,0.000024947136,0.0005132957],"genre_scores_gemma":[0.9948462,0.0017361749,0.0003525306,0.0026386594,0.0002652305,0.0000068764066,0.0000036181577,0.000014198183,0.00013646358],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9978151,0.0006252171,0.00075195613,0.0002049494,0.00015136036,0.00045141688],"domain_scores_gemma":[0.9988475,0.00023012415,0.00048873137,0.00013834814,0.00013151119,0.00016379624],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012475986,0.00023445878,0.00052825187,0.00046351008,0.00015087968,0.000027241404,0.00028514137,0.0006459051,0.000405428],"category_scores_gemma":[0.00010129446,0.00021393746,0.00013271216,0.0002524198,0.00011433231,0.00033094114,0.000055614226,0.0019963179,0.000027429158],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001326315,0.0008490925,0.027476287,0.000036941972,0.0003052949,0.0015399972,0.0014583964,0.00013604826,0.89240056,0.00094459474,0.0006718739,0.07285459],"study_design_scores_gemma":[0.011480275,0.005132859,0.59954375,0.00017776326,0.0004496811,0.008923371,0.00041331508,0.0017101358,0.27740592,0.003197683,0.09075348,0.00081177894],"about_ca_topic_score_codex":0.000016565962,"about_ca_topic_score_gemma":0.00005926337,"teacher_disagreement_score":0.61499465,"about_ca_system_score_codex":0.00014630097,"about_ca_system_score_gemma":0.000111845155,"threshold_uncertainty_score":0.8724116},"labels":[],"label_agreement":null},{"id":"W2148985010","doi":"10.1038/ajg.2010.5","title":"Hepatotoxicity Due to Hydroxycut: A Case Series","year":2010,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":148,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; United States Pharmacopeia","keywords":"Medicine; Liver injury; Jaundice; Liver transplantation; Vomiting; Abdominal pain; Nausea; Internal medicine; Gastroenterology; Surgery; Transplantation","score_opus":0.04531562246950549,"score_gpt":0.37528158152520635,"score_spread":0.32996595905570086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2148985010","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9874246,0.000009936442,0.00097048783,0.008978749,0.0020587964,0.00027195745,0.000023017888,0.00003178568,0.00023064285],"genre_scores_gemma":[0.9895186,0.00002063393,0.0010523155,0.008528002,0.00076922635,0.000021328378,7.37744e-7,0.000023668752,0.000065493885],"study_design_codex":"bench_or_experimental","study_design_gemma":"case_report","domain_scores_codex":[0.9973789,0.0011148937,0.00057311164,0.0001986701,0.00016570008,0.00056871085],"domain_scores_gemma":[0.99817747,0.00022424334,0.000707536,0.00028690547,0.00019462714,0.00040923577],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0019398829,0.00023279831,0.00061846926,0.00022475638,0.000371138,0.000024499754,0.0005235588,0.00012391467,0.00027435512],"category_scores_gemma":[0.00018028844,0.00017026786,0.00019840429,0.00028669095,0.0007738841,0.0001690431,0.00012679618,0.0024340034,0.00007734293],"study_design_candidate":"case_report","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.06055308,0.0013646185,0.11223366,0.000042591517,0.0013893151,0.021361783,0.007646838,0.0014289301,0.68903035,0.0008988073,0.004599714,0.099450335],"study_design_scores_gemma":[0.0033193536,0.02973904,0.013164887,0.00002687959,0.00045170804,0.80026615,0.0018150859,0.0007518117,0.075125754,0.0021668817,0.07267111,0.00050136476],"about_ca_topic_score_codex":0.00009279643,"about_ca_topic_score_gemma":0.00067969464,"teacher_disagreement_score":0.7789043,"about_ca_system_score_codex":0.00004817643,"about_ca_system_score_gemma":0.00006759665,"threshold_uncertainty_score":0.99986744},"labels":[],"label_agreement":null},{"id":"W2149803755","doi":"10.1093/toxsci/kft087","title":"Serum Glutamate Dehydrogenase—Biomarker for Liver Cell Death or Mitochondrial Dysfunction?","year":2013,"lang":"en","type":"letter","venue":"Toxicological Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Glutamate dehydrogenase; Mitochondrial DNA; Mitochondrion; Malate dehydrogenase; Biology; Purine nucleoside phosphorylase; Molecular biology; Riluzole; Pharmacology; Biochemistry; Glutamate receptor; Enzyme; Purine","score_opus":0.31756627084891126,"score_gpt":0.4294016581907273,"score_spread":0.11183538734181603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149803755","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.45578682,0.0012750799,0.0028595468,0.4390646,0.038049545,0.018407088,0.0020779534,0.0018902202,0.040589154],"genre_scores_gemma":[0.10665724,0.0005688997,0.004475584,0.8229798,0.014147338,0.004044811,0.00028267442,0.0001325666,0.046711065],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9938046,0.001345384,0.0008338353,0.0015538527,0.00065298215,0.0018093728],"domain_scores_gemma":[0.9961685,0.0023072667,0.0005818985,0.0003534286,0.00019998195,0.000388933],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0015501,0.00084082317,0.0008675193,0.0003082821,0.0020382812,0.00029646364,0.0012893913,0.004547516,0.016078562],"category_scores_gemma":[0.00040404993,0.0005743191,0.0005044953,0.00066149945,0.0010748609,0.00042350957,0.00028526544,0.003462738,0.0017404405],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005073255,0.00047609498,0.0003847016,0.00032245033,0.00016164854,0.00030150285,0.000106217245,0.000107671265,0.026969234,0.00015405224,0.9578286,0.0126805445],"study_design_scores_gemma":[0.0016455812,0.0013901924,0.0004101184,0.000032174332,0.00027346003,0.000098939476,0.000033107684,0.0061595445,0.027845899,0.0020128288,0.95912635,0.0009718223],"about_ca_topic_score_codex":0.00008465973,"about_ca_topic_score_gemma":0.00005427246,"teacher_disagreement_score":0.38391525,"about_ca_system_score_codex":0.00031492265,"about_ca_system_score_gemma":0.00042970083,"threshold_uncertainty_score":0.9996708},"labels":[],"label_agreement":null},{"id":"W2151187984","doi":"10.4103/2141-9248.126627","title":"Hydroxycut-induced liver toxicity","year":2014,"lang":"en","type":"article","venue":"Annals of Medical and Health Sciences Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Jaundice; Weight loss; Discontinuation; Adverse effect; Liver enzyme; Public health; Drug; Obesity; Elevated liver enzymes; Anti obesity; Environmental health; Internal medicine; Pharmacology; Pathology","score_opus":0.7719718693762418,"score_gpt":0.6565611837557206,"score_spread":0.11541068562052126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151187984","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88893574,0.0008662794,0.000089009925,0.09922289,0.00034004194,0.00036370475,0.0000050236436,0.00003060189,0.010146687],"genre_scores_gemma":[0.9835511,0.0055990005,0.000061740655,0.0102519505,0.00034644754,0.000024087865,0.000001416914,0.0000052385203,0.00015902547],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.994796,0.0018958921,0.000406646,0.00038729023,0.0016539273,0.0008602498],"domain_scores_gemma":[0.9975921,0.0009998562,0.00010751947,0.00013597404,0.00019998991,0.00096459297],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.03807512,0.0001117162,0.00028837525,0.0002807531,0.0011835325,0.000029733577,0.00055654295,0.00040420334,0.00090301654],"category_scores_gemma":[0.0011023962,0.00008820403,0.000050048708,0.0007064493,0.0013917685,0.00014218845,0.00023272891,0.001599742,0.00007569642],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001034485,0.00052685663,0.005603012,0.00055347645,0.000026879485,0.000013223564,0.0014312307,0.000009427309,0.0032847407,0.034693927,0.014471626,0.9392822],"study_design_scores_gemma":[0.0022583692,0.0070851874,0.029109754,0.0005312966,0.000010272021,0.0001017182,0.00081795227,0.115248814,0.14917307,0.0349338,0.66013145,0.0005983458],"about_ca_topic_score_codex":0.0016446089,"about_ca_topic_score_gemma":0.00033215721,"teacher_disagreement_score":0.9386838,"about_ca_system_score_codex":0.000019503419,"about_ca_system_score_gemma":0.0005787861,"threshold_uncertainty_score":0.9905041},"labels":[],"label_agreement":null},{"id":"W2152916548","doi":"10.1081/clt-66056","title":"A New Predictor of Toxicity Following Acetaminophen Overdose Based on Pretreatment Exposure","year":2005,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Calgary; Queen's University","funders":"","keywords":"Acetaminophen; Antidote; Toxicodynamics; Medicine; acetaminophen overdose; Toxicity; Nomogram; Pharmacokinetics; Area under the curve; Dosing; Pharmacology; Anesthesia; Drug overdose; Toxicokinetics; Acetylcysteine; Poison control; Emergency medicine; Internal medicine; Chemistry","score_opus":0.17564274463815252,"score_gpt":0.4689508859616383,"score_spread":0.2933081413234858,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2152916548","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9801952,0.0002083954,0.0016142175,0.002786294,0.0037308265,0.0012735924,0.000070692135,0.00021047663,0.009910254],"genre_scores_gemma":[0.98710895,0.000068279944,0.0028507276,0.0064622415,0.001424217,0.000105597486,0.000024552555,0.00004214308,0.0019133108],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99527127,0.0016870669,0.0012969082,0.00074571744,0.00031521407,0.0006838362],"domain_scores_gemma":[0.99572617,0.0025571827,0.00046666007,0.0005567671,0.000075942924,0.00061725196],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0019850815,0.00041107202,0.0009017096,0.0001816125,0.00023173199,0.000014825502,0.00045497422,0.0016043511,0.0023329637],"category_scores_gemma":[0.0010780576,0.0003860524,0.0006707635,0.000315371,0.00024676925,0.00015248578,0.00012126646,0.0016159514,0.00033756488],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007931125,0.013804438,0.28120828,0.0001872857,0.0018464592,0.00021543933,0.0010347058,0.0128144855,0.063315235,0.0031947643,0.022270452,0.59217733],"study_design_scores_gemma":[0.03593577,0.01878231,0.12926392,0.00020766872,0.0014131098,0.000036102738,0.000101593294,0.039878123,0.34700283,0.0028275887,0.4228669,0.0016840512],"about_ca_topic_score_codex":0.00001881546,"about_ca_topic_score_gemma":0.00006821213,"teacher_disagreement_score":0.59049326,"about_ca_system_score_codex":0.00027153493,"about_ca_system_score_gemma":0.00045102456,"threshold_uncertainty_score":0.99985915},"labels":[],"label_agreement":null},{"id":"W2156740013","doi":"10.1111/j.1432-2277.2010.01214.x","title":"Piroxicam and meloxicam ameliorate hepatic oxidative stress and protein carbonylation in Kupffer and sinusoidal endothelial cells promoted by ischemia-reperfusion injury","year":2011,"lang":"en","type":"article","venue":"Transplant International","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Meloxicam; Piroxicam; Oxidative stress; Medicine; Reperfusion injury; Pharmacology; Ischemia; Lipid peroxidation; Liver injury; Endocrinology; Internal medicine; Pathology","score_opus":0.050283545222146175,"score_gpt":0.32795650009927774,"score_spread":0.27767295487713156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156740013","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963681,0.00008768401,0.000184397,0.00019298687,0.00023118901,0.0007827775,0.00077631697,0.00004611159,0.001330438],"genre_scores_gemma":[0.9986916,0.00040400284,0.00022049849,0.00014705509,0.0000717909,0.00010698653,0.00009792379,0.00001729436,0.000242856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99864435,0.0002545474,0.00032321468,0.00037825416,0.00016505901,0.00023456554],"domain_scores_gemma":[0.9995471,0.00008337051,0.00011717585,0.00007008945,0.00005061693,0.00013163319],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035861344,0.00022718261,0.00020663966,0.00016076167,0.00012546255,0.000028511584,0.00010487904,0.0003124205,0.00020789914],"category_scores_gemma":[0.000016721087,0.00021957673,0.000025462352,0.0000912452,0.0001718471,0.0002477671,0.000037610414,0.0005893936,0.0000069110406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009741851,0.00027794795,0.015920427,0.000083349616,0.000064329804,0.00002083267,0.0036569817,0.000003605674,0.9714534,0.00021646955,0.000019908432,0.0073085497],"study_design_scores_gemma":[0.0015939266,0.0001929156,0.0029589024,0.0001356256,0.000041213865,0.000022077913,0.000058857306,0.004408187,0.98943824,0.0004094606,0.0004887132,0.00025189243],"about_ca_topic_score_codex":0.00039852498,"about_ca_topic_score_gemma":0.00015056162,"teacher_disagreement_score":0.017984815,"about_ca_system_score_codex":0.00004398004,"about_ca_system_score_gemma":0.000029709925,"threshold_uncertainty_score":0.8954079},"labels":[],"label_agreement":null},{"id":"W2157489045","doi":"10.1038/sj.bjp.0704500","title":"A NO‐releasing derivative of acetaminophen spares the liver by acting at several checkpoints in the Fas pathway 
THIS ARTICLE HAS BEEN RETRACTED","year":2002,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":38,"is_retracted":true,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Acetaminophen; Liver injury; Toxicity; Pharmacology; Chemistry; In vivo; Medicine; Internal medicine; Endocrinology; Biology","score_opus":0.12568480024465836,"score_gpt":0.35261757380814823,"score_spread":0.22693277356348987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157489045","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99009866,0.0030079358,0.0000463803,0.002260934,0.0011430596,0.000579639,0.000057191493,0.00001900481,0.0027872205],"genre_scores_gemma":[0.9937214,0.0019952129,0.0001036883,0.0030399945,0.00056342164,0.000027822967,0.0000036449571,0.000024484625,0.00052028993],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9952483,0.002757842,0.00086617516,0.00023393209,0.0003461441,0.0005475902],"domain_scores_gemma":[0.99729145,0.0013052918,0.00088400836,0.000093213064,0.00030382478,0.00012223939],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0020266436,0.00022409149,0.00043712772,0.00011437449,0.00067839876,0.000058866535,0.0005794019,0.00040645004,0.005235922],"category_scores_gemma":[0.0004526128,0.00018806226,0.00019292645,0.000404242,0.0004910332,0.00039765463,0.0001190897,0.0027714854,0.0000943274],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008468812,0.0010894674,0.0023133154,0.00006965206,0.00042236125,0.00090576767,0.009626699,0.0002364348,0.85682994,0.000011360436,0.04993191,0.077716194],"study_design_scores_gemma":[0.007359435,0.00067012815,0.017377222,0.00019382739,0.0004057337,0.0052434197,0.00094108476,0.01136232,0.8483586,0.00014270497,0.10747086,0.00047469523],"about_ca_topic_score_codex":0.00026873124,"about_ca_topic_score_gemma":0.00011871763,"teacher_disagreement_score":0.0772415,"about_ca_system_score_codex":0.00022850648,"about_ca_system_score_gemma":0.00007473332,"threshold_uncertainty_score":0.9995292},"labels":[],"label_agreement":null},{"id":"W2157579438","doi":"10.1146/annurev.pharmtox.40.1.43","title":"Chlorinated Methanes and Liver Injury: Highlights of the Past 50 Years","year":2000,"lang":"en","type":"review","venue":"The Annual Review of Pharmacology and Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Carbon tetrachloride; Hexobarbital; Steatosis; Liver injury; Biotransformation; Adverse Outcome Pathway; Lipid peroxidation; Cirrhosis; Chemistry; Endoplasmic reticulum; Long-term potentiation; Biochemistry; Pharmacology; Medicine; Microsome; Biology; Internal medicine; Organic chemistry; Oxidative stress; In vitro; Enzyme","score_opus":0.0860602427475752,"score_gpt":0.434710911253724,"score_spread":0.3486506685061488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157579438","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0026072096,0.98924035,9.4445477e-7,0.0014751753,0.0019870296,0.0030820542,0.00048703782,0.00003979695,0.0010804217],"genre_scores_gemma":[0.002517038,0.9927475,0.00001386494,0.0031816503,0.00045285508,0.00039248468,0.000025490523,0.000049202703,0.00061991106],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99170965,0.005491987,0.0013714897,0.00061636476,0.00021391938,0.00059661915],"domain_scores_gemma":[0.99615216,0.0017528351,0.0013361819,0.0004164512,0.00017498212,0.00016737569],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.002579446,0.00066424,0.0026997018,0.00024365583,0.0003689848,0.000007828935,0.00096028094,0.0013285457,0.0013306418],"category_scores_gemma":[0.00012887838,0.00040194267,0.0005445472,0.00069138425,0.0019389605,0.00013200485,0.0005371258,0.0023439175,0.000055489698],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025836867,0.0003345343,0.000013059628,0.05239894,0.0012058908,0.000025804664,0.00045968697,8.2347816e-7,0.00032609355,0.0016216538,0.00967178,0.9336834],"study_design_scores_gemma":[0.00058041594,0.0003642111,0.00006874513,0.005080512,0.0051251124,0.00030326654,0.000019971725,0.0000039356382,0.0009677569,0.00018389772,0.98694235,0.00035982713],"about_ca_topic_score_codex":0.000039139093,"about_ca_topic_score_gemma":0.000010618623,"teacher_disagreement_score":0.97727054,"about_ca_system_score_codex":0.00006195347,"about_ca_system_score_gemma":0.00029464997,"threshold_uncertainty_score":0.99996793},"labels":[],"label_agreement":null},{"id":"W2157706038","doi":"10.3109/1547691x.2013.860644","title":"Isoniazid-induced liver injury and immune response in mice","year":2013,"lang":"en","type":"article","venue":"Journal of Immunotoxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Liver injury; Immune system; Isoniazid; Medicine; Drug; Pharmacology; Immunology; Animal model; Toxicity; Internal medicine; Pathology; Tuberculosis","score_opus":0.07270840769424575,"score_gpt":0.3904423363837778,"score_spread":0.31773392868953204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157706038","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99273676,0.001455393,0.000033558503,0.0025613296,0.0019085212,0.0006619559,0.0000049975965,0.00002496068,0.00061251683],"genre_scores_gemma":[0.9968302,0.0006923072,0.00027675842,0.0016446338,0.0002000503,0.00005931028,8.4547236e-7,0.000027890323,0.00026797023],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9957258,0.002249837,0.0010790599,0.00023646829,0.00016766695,0.000541147],"domain_scores_gemma":[0.99762475,0.0010546151,0.0006756216,0.0001745952,0.00026388175,0.00020650339],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0033583264,0.00027204357,0.000604555,0.0006331663,0.00020578757,0.000042424246,0.0003678134,0.0008382954,0.0010495229],"category_scores_gemma":[0.0006611979,0.00025532162,0.00015080228,0.00035926295,0.00020848792,0.0005388705,0.00013677162,0.002374969,0.00021316718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0048237154,0.00041747352,0.0014599599,0.000028471924,0.000119603814,0.00013590285,0.001210204,0.00002499335,0.9562873,0.00014013727,0.00042648622,0.034925703],"study_design_scores_gemma":[0.006757442,0.0046481825,0.28454494,0.00011333002,0.00012524905,0.0021349338,0.0007643437,0.0011445356,0.67132974,0.0019589816,0.025838654,0.0006396517],"about_ca_topic_score_codex":0.00015446762,"about_ca_topic_score_gemma":0.000021275426,"teacher_disagreement_score":0.28495762,"about_ca_system_score_codex":0.00026348178,"about_ca_system_score_gemma":0.00024252139,"threshold_uncertainty_score":0.9999899},"labels":[],"label_agreement":null},{"id":"W2157946922","doi":"10.1086/375072","title":"Severe Hepatotoxicity Associated with Rifampin-Pyrazinamide Preventative Therapy Requiring Transplantation in an Individual at Low Risk for Hepatotoxicity","year":2003,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Capital District Health Authority; University of Alberta Hospital; University of Alberta","funders":"","keywords":"Medicine; Pyrazinamide; Liver transplantation; Transplantation; Internal medicine; Liver disease; Pharmacology; Disease; Therapeutic drug monitoring; Immunology; Intensive care medicine; Drug; Tuberculosis; Isoniazid; Pathology","score_opus":0.1722437410042079,"score_gpt":0.46363190914607216,"score_spread":0.2913881681418643,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157946922","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931662,0.00013853727,0.0009804347,0.000029596917,0.00077364576,0.002960021,0.0012688236,0.00032232283,0.00036039815],"genre_scores_gemma":[0.99629503,0.0010252033,0.000049911665,0.0010310846,0.00018143159,0.00088622083,0.00039369927,0.000067979185,0.000069405236],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.992533,0.004532201,0.0009950815,0.0008950259,0.00029713142,0.00074752345],"domain_scores_gemma":[0.9951462,0.0031351417,0.0006754841,0.00029866712,0.00021639351,0.0005280758],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002720975,0.000490795,0.0007307806,0.00019834243,0.0008744912,0.00006670912,0.0002427375,0.00081487634,0.00025493954],"category_scores_gemma":[0.0014477905,0.00046380723,0.0003414771,0.00051001925,0.00042555132,0.000580364,0.000033272838,0.0013709136,0.000027017502],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019942329,0.004203385,0.98200965,0.00008958822,0.00044927048,0.000040635558,0.00090050814,0.002021901,0.00089166744,0.00017297955,0.00006178507,0.0071643847],"study_design_scores_gemma":[0.01753196,0.003167003,0.9469031,0.00015663152,0.00059024914,0.000024362553,0.00015946898,0.0026753158,0.021896375,0.005335515,0.0005244261,0.0010355914],"about_ca_topic_score_codex":0.00008160535,"about_ca_topic_score_gemma":0.0028330463,"teacher_disagreement_score":0.03510656,"about_ca_system_score_codex":0.00040812918,"about_ca_system_score_gemma":0.00027872832,"threshold_uncertainty_score":0.99978137},"labels":[],"label_agreement":null},{"id":"W2158608925","doi":"10.1136/emj.18.3.178","title":"Measuring plasma paracetamol concentrations in all patients with drug overdose or altered consciousness: Does it change outcome?","year":2001,"lang":"en","type":"article","venue":"Emergency Medicine Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Thomas Hospital","funders":"","keywords":"Medicine; Acetaminophen; acetaminophen overdose; Emergency department; Drug overdose; Anesthesia; Level of consciousness; Drug; Emergency medicine; Ingestion; Poison control; Internal medicine; Pharmacology; Acetylcysteine; Psychiatry","score_opus":0.34497601382611964,"score_gpt":0.4520779844973234,"score_spread":0.10710197067120375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158608925","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97944206,0.00024620196,0.000101720616,0.007314426,0.008055377,0.0009434739,0.000020578032,0.00005105525,0.0038251],"genre_scores_gemma":[0.9891359,0.0019083276,0.000028981507,0.00077587087,0.001791933,0.00010506764,0.000021048774,0.000031110605,0.0062017106],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9968746,0.00065980124,0.0010416113,0.00030760045,0.0004719248,0.0006444873],"domain_scores_gemma":[0.99851364,0.0001654233,0.0004886433,0.0001696341,0.0002454999,0.00041715422],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0013497594,0.00032357304,0.00045469194,0.0002888954,0.00045994337,0.000012214709,0.00026535842,0.00021966377,0.026128251],"category_scores_gemma":[0.000314178,0.0002004706,0.000077681805,0.0004660581,0.00014603458,0.00047635077,0.000035645477,0.0016423309,0.000055783614],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012754108,0.0005924904,0.9629274,0.000059837806,0.00019195024,0.000051021605,0.00913717,0.00016736695,0.001044363,0.00003151141,0.02219903,0.0023224533],"study_design_scores_gemma":[0.01991125,0.0008533402,0.26447126,0.00042211055,0.000490592,0.00032330106,0.0026332135,0.0022756113,0.0021232527,0.00035903795,0.7052207,0.0009163598],"about_ca_topic_score_codex":0.00025465808,"about_ca_topic_score_gemma":0.004292317,"teacher_disagreement_score":0.69845617,"about_ca_system_score_codex":0.00019081692,"about_ca_system_score_gemma":0.00010502174,"threshold_uncertainty_score":0.974762},"labels":[],"label_agreement":null},{"id":"W2158961706","doi":"10.3109/1547691x.2014.934977","title":"Development of a novel mouse model of amodiaquine-induced liver injury with a delayed onset","year":2014,"lang":"en","type":"article","venue":"Journal of Immunotoxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Liver injury; Amodiaquine; CD8; Medicine; Immunology; Internal medicine; Biology; Endocrinology; Malaria; Chloroquine","score_opus":0.1286805316951339,"score_gpt":0.3840023780771183,"score_spread":0.2553218463819844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158961706","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98337674,0.000060945615,0.015103344,0.000119746976,0.00047664013,0.00043575946,0.000040129355,0.000018919043,0.00036776037],"genre_scores_gemma":[0.98110294,0.00006176911,0.01813861,0.00043979328,0.000085458145,0.000030194476,0.0000043482237,0.00003340114,0.000103475446],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971563,0.0004969909,0.0013948356,0.00021408816,0.00031543014,0.00042235234],"domain_scores_gemma":[0.9968765,0.0003654781,0.0017211976,0.0002509629,0.000602828,0.00018308412],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002255176,0.00029681346,0.00083097455,0.00047747078,0.0001736981,0.000007832908,0.0004757646,0.00064295874,0.00010552901],"category_scores_gemma":[0.00020650131,0.00024996715,0.00019203254,0.0002769089,0.00025052612,0.00021166969,0.000105075946,0.0013193801,0.0000088443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0049545476,0.0015543245,0.00037272242,0.00009686999,0.0006022534,0.0000062026998,0.002370563,0.0036222974,0.973808,0.00036897045,0.000088960456,0.012154272],"study_design_scores_gemma":[0.0046072607,0.0024416747,0.00056002964,0.00006456321,0.00019603553,0.00018124293,0.00015008639,0.01885818,0.9707044,0.0000967061,0.0018685814,0.00027129025],"about_ca_topic_score_codex":0.000019753854,"about_ca_topic_score_gemma":0.00006787451,"teacher_disagreement_score":0.015235883,"about_ca_system_score_codex":0.00016974298,"about_ca_system_score_gemma":0.00077449257,"threshold_uncertainty_score":0.99999523},"labels":[],"label_agreement":null},{"id":"W2159248641","doi":"10.2174/1389200043489054","title":"The Effect of Liver Cirrhosis on the Regulation and Expression of Drug Metabolizing Enzymes","year":2004,"lang":"en","type":"review","venue":"Current Drug Metabolism","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":138,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Cirrhosis; Glucuronidation; Liver disease; Drug; Cytochrome P450; Alcoholic liver disease; Enzyme; Sulfation; Pharmacology; Medicine; Internal medicine; Biology; Biochemistry; Microsome","score_opus":0.12976048990242622,"score_gpt":0.42963254847033594,"score_spread":0.2998720585679097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159248641","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0056102755,0.98794866,0.000013164299,0.000080415084,0.0034998236,0.002437107,0.000110880435,0.000042577918,0.00025711398],"genre_scores_gemma":[0.02411083,0.97472996,0.000012561436,0.000018847677,0.00048875884,0.00042085396,0.00003286043,0.00005037657,0.00013497702],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9929116,0.0048065656,0.0009811515,0.00048663007,0.0004083614,0.00040570577],"domain_scores_gemma":[0.9941984,0.0037230393,0.0013060054,0.0005420228,0.00010611003,0.00012441482],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0037718706,0.0006181382,0.0016503012,0.0002510715,0.000688416,0.000037438458,0.00056959665,0.00044215174,0.00008739088],"category_scores_gemma":[0.0003827435,0.00032363486,0.0006707196,0.00045995662,0.00043370377,0.00013354926,0.00020614213,0.001937064,0.00002837512],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009922754,0.00008764412,0.000009500835,0.008913182,0.00023946923,6.09871e-7,0.0007587864,0.000020421976,0.0003996543,0.006083743,0.00063509017,0.9827527],"study_design_scores_gemma":[0.0005995499,0.000029569035,0.00005960718,0.004974272,0.0024374232,0.000005774144,0.000021889888,0.000034569588,0.06983869,0.00044637657,0.921263,0.00028933273],"about_ca_topic_score_codex":0.000033497454,"about_ca_topic_score_gemma":0.0000049633645,"teacher_disagreement_score":0.98246336,"about_ca_system_score_codex":0.00006250339,"about_ca_system_score_gemma":0.00013438296,"threshold_uncertainty_score":0.99992156},"labels":[],"label_agreement":null},{"id":"W2159470314","doi":"10.1111/fcp.12157","title":"The effect of ageing on isoniazid pharmacokinetics and hepatotoxicity in Fischer 344 rats","year":2015,"lang":"en","type":"article","venue":"Fundamental and Clinical Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"National Health and Medical Research Council; National Institutes of Health","keywords":"Isoniazid; Pharmacokinetics; Steatosis; Alanine transaminase; Pharmacology; Medicine; Toxicity; Internal medicine; Transaminase; Liver injury; Endocrinology; Chemistry; Tuberculosis; Enzyme; Pathology; Biochemistry","score_opus":0.15814844315206034,"score_gpt":0.4887832471259452,"score_spread":0.33063480397388484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159470314","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99035615,0.0009746658,0.000005722644,0.0016537763,0.0037066385,0.0010135748,0.000030538406,0.000045121495,0.0022137994],"genre_scores_gemma":[0.99478704,0.0016585671,0.00002004718,0.0026906484,0.0004995689,0.00010009784,0.00000589908,0.000022946473,0.00021520481],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9953556,0.0026434897,0.0008063928,0.0004818687,0.00019454144,0.0005181079],"domain_scores_gemma":[0.9959847,0.0031293978,0.0002689565,0.00013329118,0.000046227167,0.00043744245],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0038070793,0.00031503313,0.0005589654,0.000099744895,0.00029730593,0.00002661147,0.00022934661,0.00047505103,0.00014150327],"category_scores_gemma":[0.00026428688,0.0002318983,0.00011900803,0.00021557281,0.0009052421,0.00011030535,0.00023881788,0.0017486853,0.000043739692],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01482994,0.0014125217,0.6731694,0.00020471076,0.0007526599,0.00023852823,0.0008342813,0.00022196848,0.08784077,0.00031785772,0.0122282775,0.20794912],"study_design_scores_gemma":[0.037935268,0.014146671,0.08595457,0.00010870806,0.0010068695,0.000120578414,0.00045809153,0.021415528,0.4968595,0.0015218569,0.33930057,0.0011718007],"about_ca_topic_score_codex":0.000071689064,"about_ca_topic_score_gemma":0.000067838235,"teacher_disagreement_score":0.58721477,"about_ca_system_score_codex":0.00007929325,"about_ca_system_score_gemma":0.000056448276,"threshold_uncertainty_score":0.9456538},"labels":[],"label_agreement":null},{"id":"W2160273926","doi":"10.1124/jpet.112.202010","title":"The UDP-Glucuronosyltransferase (UGT) 1A Polymorphism c.2042C&gt;G (rs8330) Is Associated with Increased Human Liver Acetaminophen Glucuronidation, Increased UGT1A Exon 5a/5b Splice Variant mRNA Ratio, and Decreased Risk of Unintentional Acetaminophen-Induced Acute Liver Failure","year":2013,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":80,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Glucuronidation; Acetaminophen; Exon; Glucuronosyltransferase; Single-nucleotide polymorphism; Liver injury; Biology; Chemistry; Molecular biology; Internal medicine; Endocrinology; Genotype; Gene; Pharmacology; Genetics; Biochemistry; Medicine; Enzyme; Microsome","score_opus":0.043175391839216884,"score_gpt":0.3330161434244821,"score_spread":0.28984075158526523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2160273926","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939385,0.0027982383,0.00022044333,0.0010139623,0.0005671055,0.001186346,0.00012409055,0.000041201176,0.000110082285],"genre_scores_gemma":[0.9935365,0.0027311975,0.00023902788,0.0028939166,0.00029979696,0.00010172318,0.000039069928,0.000056950423,0.000101862905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99522996,0.0021852173,0.0010516687,0.00045070876,0.0004541708,0.00062828045],"domain_scores_gemma":[0.99651253,0.0009970391,0.0012567751,0.00021111387,0.0005854445,0.00043708773],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0014881424,0.00058190763,0.00072908687,0.00025685434,0.0013866303,0.00008794338,0.00044098482,0.0006354325,0.0014265149],"category_scores_gemma":[0.00004197338,0.00044714488,0.00022029299,0.00031275957,0.0008406534,0.00068344956,0.00010992931,0.0016631382,0.000015986547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025851252,0.0012838503,0.0029786308,0.00003153773,0.0041819247,0.00009946728,0.0027789397,0.000021679825,0.9833039,0.0002618481,0.00069097546,0.0017821448],"study_design_scores_gemma":[0.013351918,0.0024978037,0.01686885,0.00006332416,0.0030091617,0.0005123325,0.0008942489,0.0050877756,0.9540286,0.00024562905,0.002841123,0.0005992479],"about_ca_topic_score_codex":0.0004846292,"about_ca_topic_score_gemma":0.00006295878,"teacher_disagreement_score":0.02927529,"about_ca_system_score_codex":0.00029331815,"about_ca_system_score_gemma":0.00032424077,"threshold_uncertainty_score":0.99991345},"labels":[],"label_agreement":null},{"id":"W2160469125","doi":"10.14740/jcgo.v4i3.343","title":"Methyldopa Hepatotoxicity: A Paradoxical High-Risk Pregnancy","year":2015,"lang":"en","type":"article","venue":"Journal of Clinical Gynecology and Obstetrics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Methyldopa; Medicine; Discontinuation; Pregnancy; Jaundice; Prednisone; Diabetes mellitus; Gestation; Blood pressure; Obstetrics; Internal medicine; Endocrinology","score_opus":0.3104783080150642,"score_gpt":0.49515882666736283,"score_spread":0.18468051865229862,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2160469125","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9778913,0.0041956436,0.0012055528,0.0010386882,0.0136750005,0.00040811277,0.000026211508,0.000047104277,0.0015123615],"genre_scores_gemma":[0.9891427,0.00610184,0.0018613057,0.0016109479,0.00089263526,0.000013847067,0.0000030206133,0.000026422551,0.0003472692],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.992847,0.0036163114,0.002197085,0.00039068735,0.0003989949,0.0005498729],"domain_scores_gemma":[0.9793367,0.016900739,0.0017519773,0.00024311413,0.00062105927,0.0011464297],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.007894158,0.00031243378,0.0012071825,0.00035717772,0.00028714567,0.000034876408,0.0004159556,0.00167257,0.00017790576],"category_scores_gemma":[0.042594053,0.0002592845,0.00038395778,0.0006035356,0.00052047655,0.00032904607,0.00016093279,0.004532005,0.00010016798],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012108114,0.0018851274,0.4587765,0.00006337281,0.0006700594,0.00089169445,0.0005272804,0.00029610324,0.00015013751,0.002671085,0.002951448,0.5299064],"study_design_scores_gemma":[0.035461113,0.013831303,0.19830678,0.00018605868,0.0024482661,0.0013358373,0.0008072899,0.005618622,0.008319043,0.075420156,0.65671366,0.0015518932],"about_ca_topic_score_codex":0.000019569157,"about_ca_topic_score_gemma":0.000021963355,"teacher_disagreement_score":0.65376216,"about_ca_system_score_codex":0.00011206719,"about_ca_system_score_gemma":0.00052576733,"threshold_uncertainty_score":0.99998593},"labels":[],"label_agreement":null},{"id":"W2160691532","doi":"10.6000/1927-5129.2013.09.13","title":"Comparison of Hepatic Parameters Following Administration of Antihypertensive, Hypolipidemic and Hypoglycemic Drugs","year":2013,"lang":"en","type":"article","venue":"Journal of Basic & Applied Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Lisinopril; Atorvastatin; Acarbose; Amlodipine; Medicine; Metformin; Glimepiride; Losartan; Pharmacology; Glibenclamide; Ramipril; Liver function; Internal medicine; Bilirubin; Drug; Alkaline phosphatase; Endocrinology; Angiotensin-converting enzyme; Chemistry; Angiotensin II; Diabetes mellitus; Biochemistry; Blood pressure; Enzyme; Insulin","score_opus":0.1415857342599396,"score_gpt":0.42846346184933526,"score_spread":0.28687772758939567,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2160691532","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969525,0.00027138606,0.00015911926,0.0003631274,0.0006570622,0.00031078586,0.0000026079192,0.0000076406395,0.0012758209],"genre_scores_gemma":[0.99791557,0.00007818569,0.0016269494,0.00028783467,0.00006660121,0.000007978866,5.634026e-7,0.000005864348,0.000010479764],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99823475,0.0001992872,0.0008411963,0.00016325373,0.0003298651,0.00023165444],"domain_scores_gemma":[0.99794996,0.0006821269,0.0010220071,0.0000798175,0.00013631217,0.00012976205],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015190704,0.00013831185,0.00052550045,0.00023658237,0.00019973736,0.000022328077,0.00023743637,0.00017143326,0.00004152642],"category_scores_gemma":[0.0001392384,0.000113052745,0.00012117658,0.00033796893,0.0005045881,0.00028706735,0.000031732732,0.00048458076,0.000006029665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021202724,0.00024075557,0.041624375,0.00009081869,0.0001301425,0.0000028198817,0.0025280688,0.0005471862,0.9253929,0.0004010859,0.00026155767,0.02856822],"study_design_scores_gemma":[0.0015607706,0.0009472221,0.011789005,0.00010462795,0.00026407323,0.00007369389,0.0049751718,0.007888795,0.96771073,0.004118192,0.00033511763,0.00023260196],"about_ca_topic_score_codex":0.00004923678,"about_ca_topic_score_gemma":0.00000540813,"teacher_disagreement_score":0.042317785,"about_ca_system_score_codex":0.000028735445,"about_ca_system_score_gemma":0.00017088557,"threshold_uncertainty_score":0.46101573},"labels":[],"label_agreement":null},{"id":"W2160775206","doi":"10.1002/hep.23267","title":"Novel Mechanisms of Protection Against Acetaminophen Hepatotoxicity in Mice by Glutathione and N-Acetylcysteine","year":2009,"lang":"en","type":"article","venue":"Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":434,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Saint-Luc","funders":"National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Alcohol Abuse and Alcoholism","keywords":"Glutathione; Acetaminophen; Acetylcysteine; Pharmacology; Chemistry; Liver injury; Mitochondrion; Adenosine triphosphate; Metabolite; Peroxynitrite; Biochemistry; Antioxidant; Medicine; Enzyme; Superoxide","score_opus":0.07799522737969601,"score_gpt":0.35821283733906234,"score_spread":0.28021760995936634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2160775206","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98326033,0.00031453697,0.0116539,0.0016203116,0.00049803196,0.0011621036,0.00007024191,0.00011248063,0.0013080619],"genre_scores_gemma":[0.99677145,0.0002520403,0.00081963255,0.0017896866,0.00005440366,0.00011401224,0.000027745005,0.000021338097,0.00014971262],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975733,0.00055383303,0.0006472551,0.00052794005,0.00016006066,0.000537603],"domain_scores_gemma":[0.99911374,0.00013277926,0.00031060222,0.00018164999,0.000088359084,0.0001728569],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009443107,0.0003158062,0.0006070456,0.00027498885,0.00018548343,0.000010511168,0.00019271334,0.00089891965,0.00007596632],"category_scores_gemma":[0.00013677952,0.0003391484,0.00008043037,0.00044213296,0.00018969187,0.00018832143,0.00006527473,0.0010633998,0.000028052264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044125848,0.0006233544,0.0017480415,0.000080817976,0.000041067615,0.000018565215,0.00041668865,0.0000446599,0.970952,0.002625576,0.00012966174,0.022878332],"study_design_scores_gemma":[0.0038066811,0.00069121027,0.0012376221,0.000038255675,0.000050321796,0.00020411825,0.00010145732,0.020638673,0.96442795,0.0045332345,0.0038610708,0.00040941552],"about_ca_topic_score_codex":0.00031602016,"about_ca_topic_score_gemma":0.00026205558,"teacher_disagreement_score":0.022468915,"about_ca_system_score_codex":0.00013661853,"about_ca_system_score_gemma":0.000075548596,"threshold_uncertainty_score":0.99990606},"labels":[],"label_agreement":null},{"id":"W2161544088","doi":"10.3109/15563650.2010.523829","title":"Multiplying the serum aminotransferase by the acetaminophen concentration to predict toxicity following overdose","year":2010,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; University of Calgary; Health Sciences Centre; Queen's University","funders":"","keywords":"Acetaminophen; Medicine; Interquartile range; acetaminophen overdose; Toxicity; Drug overdose; Internal medicine; Ingestion; Liver injury; Gastroenterology; Acetylcysteine; Anesthesia; Poison control; Emergency medicine; Chemistry","score_opus":0.1511209454416831,"score_gpt":0.4709681632637633,"score_spread":0.31984721782208014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2161544088","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9678251,0.000073708536,0.0010421713,0.015160231,0.011265691,0.0022749868,0.000119934906,0.00020134277,0.002036817],"genre_scores_gemma":[0.9712579,0.00006005736,0.00013764513,0.02604899,0.0013886694,0.00036016223,0.000024309036,0.00003882863,0.00068339927],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9945715,0.0024580748,0.0010533468,0.00073167373,0.00028975928,0.000895617],"domain_scores_gemma":[0.9938829,0.004655076,0.00022500481,0.00064279226,0.000100543,0.0004936968],"candidate_categories":["metaepi_narrow","sts","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.005093199,0.0003816383,0.00052242464,0.000043522094,0.0014202857,0.000083663406,0.00092781644,0.0013585258,0.0007571147],"category_scores_gemma":[0.0022630082,0.00025713578,0.00042432972,0.0003763919,0.00069548126,0.00021117,0.00021019996,0.004434716,0.00036895493],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00081249076,0.0013102174,0.08863561,0.000028291292,0.00051011116,0.000049621274,0.0017402109,0.00031554265,0.73639214,0.0024815241,0.015658332,0.15206592],"study_design_scores_gemma":[0.005907109,0.0012470849,0.06562289,0.000022809785,0.0005206178,0.000077396035,0.0003771319,0.010369727,0.25690246,0.0012314826,0.656847,0.0008743099],"about_ca_topic_score_codex":0.000048970684,"about_ca_topic_score_gemma":0.00040015572,"teacher_disagreement_score":0.6411886,"about_ca_system_score_codex":0.00011278997,"about_ca_system_score_gemma":0.0001768011,"threshold_uncertainty_score":0.9999881},"labels":[],"label_agreement":null},{"id":"W2161643992","doi":"10.1146/annurev.pharmtox.47.120505.105150","title":"Idiosyncratic Drug Reactions: Current Understanding","year":2006,"lang":"en","type":"review","venue":"The Annual Review of Pharmacology and Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":299,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Idiosyncrasy; Circumstantial evidence; Drug; Mechanism (biology); Biology; Computational biology; Pharmacology; Epistemology","score_opus":0.22185725128586767,"score_gpt":0.4982578173616561,"score_spread":0.27640056607578845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2161643992","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000022092718,0.98439234,0.00008075649,0.001667666,0.0054345015,0.0038878785,0.00038524982,0.00011495261,0.0040145763],"genre_scores_gemma":[0.00031715713,0.994338,0.00002079723,0.0023981119,0.0010210286,0.00093509554,0.00014159575,0.00007760027,0.0007506107],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9893493,0.006500014,0.0021565086,0.0008253828,0.00027116138,0.00089761923],"domain_scores_gemma":[0.99378335,0.003454601,0.0018993772,0.00042965222,0.00020322789,0.00022977154],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0046177567,0.00092258933,0.003227709,0.00042306626,0.00083511946,0.000018842122,0.00087114034,0.0010935846,0.001064698],"category_scores_gemma":[0.00028231012,0.00066146406,0.0007984315,0.00086188904,0.0012737712,0.00022913555,0.00039538424,0.004235405,0.00020348952],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000064506596,0.000508904,0.0000034780724,0.16992028,0.0009097418,0.00003670892,0.00019995222,0.00000399916,0.000050392107,0.0076963543,0.08251455,0.7380911],"study_design_scores_gemma":[0.0005929622,0.00015878388,0.0000015088121,0.01648809,0.005944326,0.00038570687,0.00006904916,0.000017587858,0.00008485622,0.0016579288,0.97403884,0.00056038855],"about_ca_topic_score_codex":0.00003112706,"about_ca_topic_score_gemma":0.000023864102,"teacher_disagreement_score":0.89152426,"about_ca_system_score_codex":0.0004271437,"about_ca_system_score_gemma":0.0006099148,"threshold_uncertainty_score":0.9998485},"labels":[],"label_agreement":null},{"id":"W2163147842","doi":"10.51847/wbwoirn","title":"10.51847/wbWOirN","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Glutathione; Glutathione reductase; Chemistry; Antioxidant; Oxidative stress; Superoxide dismutase; Lipid peroxidation; Glutathione peroxidase; Biochemistry; Catalase; Vitamin C; Vitamin E; Pharmacology; Enzyme; Biology","score_opus":0.06484958661527472,"score_gpt":0.3428990662216541,"score_spread":0.2780494796063794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163147842","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03179478,0.000051384777,0.0000022103916,0.00082286453,0.000039378396,0.00047479224,0.000036079033,0.00027737234,0.9665011],"genre_scores_gemma":[0.014033465,0.0000029068121,0.000055765526,0.001017512,0.00037872655,0.00008344469,0.000018961702,0.000027448292,0.9843818],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99862516,0.0002852085,0.00023067107,0.0002939457,0.00013134853,0.0004336707],"domain_scores_gemma":[0.99928916,0.000116059375,0.00003957974,0.00021289439,0.00004605771,0.00029627723],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004826042,0.0001915632,0.00019771268,0.00010044999,0.00029792878,0.000025414874,0.00023754605,0.00033013377,0.99386954],"category_scores_gemma":[0.000039253926,0.00020169049,0.000084832274,0.0002883967,0.00006078326,0.00011930577,0.000038000344,0.00057709124,0.9830451],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035122762,0.0001487983,0.0000023315251,0.000010323017,0.000046622587,0.000013759623,0.00006866411,0.0004334989,0.004185729,0.0000073165693,0.024299247,0.97043246],"study_design_scores_gemma":[0.00053216383,0.00016644278,0.000056245895,0.0000075874614,0.000041157808,0.000023117811,0.0000013702236,0.000887918,0.00517805,0.00002291761,0.99283475,0.00024827122],"about_ca_topic_score_codex":0.000027316702,"about_ca_topic_score_gemma":6.81194e-7,"teacher_disagreement_score":0.9701842,"about_ca_system_score_codex":0.000069878406,"about_ca_system_score_gemma":0.00004117948,"threshold_uncertainty_score":0.82246995},"labels":[],"label_agreement":null},{"id":"W2168563493","doi":"10.4021/gr2008.10.1231","title":"Diphenyl Dimethyl Bicarboxylate in the Treatment of Viral Hepatitis, Adjuvant or Curative?","year":2008,"lang":"en","type":"review","venue":"Gastroenterology Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Adjuvant; Malignancy; Viral hepatitis; Gastroenterology; Internal medicine; Clinical trial; Hepatitis; Adjuvant therapy; Liver disease; Pharmacology; Immunology; Chemotherapy","score_opus":0.46065176408010666,"score_gpt":0.5633345951136096,"score_spread":0.10268283103350295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168563493","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06431671,0.9290217,0.000015520885,0.00035916825,0.00090062915,0.004288588,0.00032459883,0.000042784486,0.0007302829],"genre_scores_gemma":[0.009949888,0.98701346,0.00004201964,0.00015576903,0.0003428346,0.0018857194,0.00012206316,0.000054287717,0.00043397464],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.982254,0.013987744,0.0011479104,0.0007515599,0.0005012128,0.0013575503],"domain_scores_gemma":[0.9963913,0.002214428,0.00040767505,0.00063111854,0.00016508403,0.0001903835],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0022449533,0.0006115022,0.0020825914,0.0009031154,0.00043982663,0.000021385214,0.00097151956,0.0011417301,0.00039903627],"category_scores_gemma":[0.00017535189,0.0003683888,0.00056906487,0.0008471698,0.001207108,0.00010219706,0.00015886268,0.0034895525,0.00017881043],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002008298,0.0033974429,0.012272878,0.0019702928,0.00094983773,0.0010293821,0.0032065536,0.000011998064,0.00005410847,0.00011620349,0.0014582298,0.97352475],"study_design_scores_gemma":[0.0017960725,0.0043157507,0.00091164885,0.000546508,0.00023443197,0.00051596155,0.00007472733,0.00006515685,0.00007133922,0.00011158667,0.99114984,0.0002069687],"about_ca_topic_score_codex":0.00050831056,"about_ca_topic_score_gemma":0.0012606642,"teacher_disagreement_score":0.9896916,"about_ca_system_score_codex":0.00049042556,"about_ca_system_score_gemma":0.00045399665,"threshold_uncertainty_score":0.9998768},"labels":[],"label_agreement":null},{"id":"W2168656522","doi":"10.1007/s11095-008-9791-0","title":"Naringenin-Loaded Nanoparticles Improve the Physicochemical Properties and the Hepatoprotective Effects of Naringenin in Orally-Administered Rats with CCl4-Induced Acute Liver Failure","year":2008,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":233,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Science Council","keywords":"Naringenin; Pharmacology; Chemistry; Antioxidant; Bioavailability; Carbon tetrachloride; Lipid peroxidation; Oral administration; In vivo; CCL4; Oxidative stress; Biochemistry; Medicine; Flavonoid; Biology; Organic chemistry","score_opus":0.27008312181929434,"score_gpt":0.43625017587421244,"score_spread":0.1661670540549181,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168656522","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913623,0.00094496267,0.000018067089,0.0035191837,0.00016175653,0.0036397018,0.000008097205,0.00005670572,0.00028926088],"genre_scores_gemma":[0.9974533,0.0003773505,0.000063787294,0.00043717396,0.0001712274,0.0012847602,0.0000020350872,0.00004092689,0.00016947949],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9940087,0.00313006,0.0004700482,0.00062099315,0.00076036796,0.0010098033],"domain_scores_gemma":[0.99672294,0.002136089,0.0001279145,0.00037410698,0.00033212628,0.00030684276],"candidate_categories":["sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0027436805,0.00035739798,0.00052918895,0.00016905494,0.00095418934,0.00005834288,0.00059383287,0.00037202862,0.000039062565],"category_scores_gemma":[0.00061017845,0.00020240276,0.00011788118,0.00082746986,0.0029919702,0.00022834167,0.0004846968,0.0036908647,0.00004435698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009200822,0.000517023,0.0010246972,0.00027712306,0.00037201014,0.00019945625,0.007516343,0.000009467226,0.9731609,0.00069127633,0.000046610938,0.0069842604],"study_design_scores_gemma":[0.006284849,0.0005554256,0.0008776711,0.00008785357,0.00014400273,0.00012462992,0.00033972794,0.00621505,0.9838836,0.0003996826,0.0008258424,0.00026161844],"about_ca_topic_score_codex":0.00027494816,"about_ca_topic_score_gemma":0.000087509776,"teacher_disagreement_score":0.010722736,"about_ca_system_score_codex":0.00014986395,"about_ca_system_score_gemma":0.0002764348,"threshold_uncertainty_score":0.9997213},"labels":[],"label_agreement":null},{"id":"W2168709593","doi":"10.1211/jpp.58.1.0018","title":"Protective effect of glycoprotein isolated from <i>Ulmus davidiana</i> Nakai on carbon tetrachloride-induced mouse liver injury","year":2005,"lang":"en","type":"article","venue":"Journal of Pharmacy and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"TBARS; Chemistry; Carbon tetrachloride; Lipid peroxidation; Antioxidant; Biochemistry; Lactate dehydrogenase; Glutathione peroxidase; Thiobarbituric acid; Glutathione; Pharmacology; Liver injury; Catalase; Enzyme; Biology","score_opus":0.052534563216831504,"score_gpt":0.3900643336066315,"score_spread":0.33752977038980003,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168709593","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917895,0.0014379037,0.000068900685,0.0010575748,0.0030180125,0.0016843515,0.00012541309,0.00007336449,0.0007449366],"genre_scores_gemma":[0.99410784,0.0010418379,0.000081038954,0.0021542911,0.0023452912,0.00010965957,0.000008561736,0.00006660507,0.00008485679],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99444735,0.0025261578,0.0013401515,0.0005322736,0.00044502632,0.0007090629],"domain_scores_gemma":[0.9961438,0.0013468683,0.0013661996,0.00020591602,0.00034949766,0.000587685],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0023985987,0.00063481205,0.0011232707,0.0005937341,0.00032472424,0.000027312684,0.00051177636,0.00063852756,0.0010065075],"category_scores_gemma":[0.00018023705,0.0005611255,0.0003484816,0.0004698676,0.00028250623,0.00048920716,0.00012355357,0.0038605954,0.000043801603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.021935672,0.00077843235,0.0012572459,0.00018393932,0.00087977754,0.00021102629,0.0010674753,0.0003497017,0.8615737,0.000021584967,0.0006237055,0.11111772],"study_design_scores_gemma":[0.011276802,0.004032219,0.00018404379,0.000068181005,0.0009051713,0.00017964096,0.000032159365,0.0069415425,0.95019543,0.00011460332,0.025599774,0.00047040946],"about_ca_topic_score_codex":0.0003749985,"about_ca_topic_score_gemma":0.00003299924,"teacher_disagreement_score":0.110647306,"about_ca_system_score_codex":0.00028906253,"about_ca_system_score_gemma":0.0002317032,"threshold_uncertainty_score":0.9999067},"labels":[],"label_agreement":null},{"id":"W2168969562","doi":"10.3109/1547691x.2012.724730","title":"A novel T<sub>H</sub>17-type cell is rapidly increased in the liver in response to acetaminophen-induced liver injury: T<sub>H</sub>17 cells and the innate immune response","year":2012,"lang":"en","type":"article","venue":"Journal of Immunotoxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Immune system; Acetaminophen; Liver injury; Acquired immune system; Innate immune system; Immunology; Natural killer T cell; Cytokine; Interleukin 12; Interleukin 21; T cell; Biology; Cytotoxic T cell; Medicine; Pharmacology; In vitro","score_opus":0.05805227198676585,"score_gpt":0.34176945414529586,"score_spread":0.28371718215853003,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168969562","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893669,0.0025876493,0.000055642253,0.0036892346,0.001957446,0.0021621939,0.000042384487,0.000026013244,0.0001125682],"genre_scores_gemma":[0.9858825,0.0020562937,0.00010768618,0.011266512,0.00037919916,0.00016474363,0.0000032318255,0.00006732554,0.00007249559],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9838879,0.012140096,0.0017120334,0.00047500565,0.00050347426,0.0012814897],"domain_scores_gemma":[0.99206394,0.0054461067,0.0011351263,0.00063085556,0.00035459196,0.00036936795],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.023913153,0.0006417159,0.0010944484,0.0011836124,0.00055391144,0.00009105644,0.0010804125,0.0012358963,0.000111480214],"category_scores_gemma":[0.0015198389,0.00047512326,0.00033373554,0.0014198766,0.00057486823,0.00051304646,0.00040610987,0.004354737,0.00014923568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.10848966,0.0014305986,0.00041366558,0.00003723068,0.00018179888,0.00017425616,0.013042954,0.00013094512,0.870551,0.000028626931,0.0014417769,0.004077489],"study_design_scores_gemma":[0.0115792565,0.0021683604,0.06815766,0.00008282459,0.00021527395,0.0007287243,0.00085968024,0.00039712386,0.9040739,0.000063098545,0.01115766,0.00051643205],"about_ca_topic_score_codex":0.00011554815,"about_ca_topic_score_gemma":0.00009061219,"teacher_disagreement_score":0.09691041,"about_ca_system_score_codex":0.0005027838,"about_ca_system_score_gemma":0.00060548884,"threshold_uncertainty_score":0.99977005},"labels":[],"label_agreement":null},{"id":"W2186509442","doi":"10.7324/japs.2013.3918","title":"Effect of Aframomum melegueta on carbon tetrachloride induced liver injury","year":2013,"lang":"en","type":"article","venue":"Journal of Applied Pharmaceutical Science","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institut national de la recherche scientifique","keywords":"Carbon tetrachloride; Zingiberaceae; Traditional medicine; Liver injury; Chemistry; Medicine; Pharmacology; Organic chemistry; Rhizome","score_opus":0.07357595787732121,"score_gpt":0.42406554998058615,"score_spread":0.3504895921032649,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2186509442","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97033954,0.00006253738,0.000031949734,0.00035491626,0.0020369794,0.0008717719,0.0000044474873,0.00003467965,0.02626316],"genre_scores_gemma":[0.9982149,0.00010197532,0.00013807447,0.00097036886,0.00048264558,0.00004117541,4.587069e-7,0.000021389222,0.00002899752],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996592,0.00041594583,0.00085645565,0.00038173448,0.001014599,0.00073928066],"domain_scores_gemma":[0.9969732,0.0010645642,0.0006153896,0.00024130892,0.00034528607,0.00076023926],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0056527816,0.00033500325,0.0005904553,0.00048281372,0.00030624119,0.000056836932,0.0008837324,0.00039345046,0.00063712004],"category_scores_gemma":[0.00037330054,0.00025499868,0.00019261826,0.0010915854,0.0008244493,0.00039575744,0.00014610054,0.0026625388,0.00013188783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016541124,0.00031396296,0.00036566108,0.00008357774,0.00006305639,0.000018677965,0.00027708913,0.00013393146,0.8191409,0.0015053268,0.00012957245,0.17631415],"study_design_scores_gemma":[0.0016468284,0.0017523743,0.00093426113,0.000037657446,0.00015435572,0.000050151906,0.00003746191,0.0042661717,0.98571706,0.0006568067,0.0044927443,0.0002541459],"about_ca_topic_score_codex":0.0000261211,"about_ca_topic_score_gemma":8.76462e-7,"teacher_disagreement_score":0.17605999,"about_ca_system_score_codex":0.00025707774,"about_ca_system_score_gemma":0.00025483716,"threshold_uncertainty_score":0.9999902},"labels":[],"label_agreement":null},{"id":"W2199603535","doi":"10.1371/journal.pone.0139299","title":"Detection of Ophthalmic Acid in Serum from Acetaminophen-Induced Acute Liver Failure Patients Is More Frequent in Non-Survivors","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; U.S. Public Health Service; National Institutes of Health; University of Alberta","keywords":"Acetaminophen; Medicine; Glutathione; Internal medicine; Bilirubin; Liver failure; Oxidative stress; Gastroenterology; Pharmacology; Chemistry; Biochemistry","score_opus":0.15389174469389125,"score_gpt":0.34807710362884575,"score_spread":0.1941853589349545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2199603535","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99751997,0.0000769444,0.00001409516,0.0002736739,0.0004672145,0.001075393,0.00019241782,0.00004548152,0.00033483523],"genre_scores_gemma":[0.9989425,0.00006630834,0.0002143192,0.00037038515,0.00011215975,0.00015128359,0.00004419312,0.00003266706,0.00006621697],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99778783,0.0004578528,0.00052739616,0.00043074676,0.00036989804,0.00042629524],"domain_scores_gemma":[0.9990194,0.00008976535,0.00024579576,0.00026547103,0.00017666585,0.00020292953],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004835529,0.0002767397,0.00048127977,0.0003126308,0.000074046955,0.000012517185,0.00026075725,0.00072557933,0.00021445935],"category_scores_gemma":[0.0000877239,0.00030376608,0.00007571374,0.000509973,0.00006762444,0.00031126462,0.000106280524,0.0012265346,0.000154317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049131265,0.0028823216,0.21541637,0.00009211186,0.00032236092,0.000041812506,0.0074359416,0.000038341856,0.76920533,0.0000023580756,0.000020861255,0.004050886],"study_design_scores_gemma":[0.0033415921,0.00032948726,0.10641109,0.00010993239,0.00016241791,0.0000018286993,0.000348946,0.0031576538,0.885591,0.00021338508,0.000051083287,0.0002816297],"about_ca_topic_score_codex":0.0021630083,"about_ca_topic_score_gemma":0.0020842755,"teacher_disagreement_score":0.11638564,"about_ca_system_score_codex":0.00034193762,"about_ca_system_score_gemma":0.000075400516,"threshold_uncertainty_score":0.99994147},"labels":[],"label_agreement":null},{"id":"W2202431101","doi":"10.3109/15563650.2015.1110591","title":"Nomogram line crossing after acetaminophen combination product overdose","year":2015,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Nomogram; Acetaminophen; Drug overdose; Medicine; Product line; acetaminophen overdose; Medical emergency; Emergency medicine; Poison control; Anesthesia; Engineering; Internal medicine; Chemistry; Acetylcysteine","score_opus":0.3852964955492451,"score_gpt":0.5314858187712517,"score_spread":0.14618932322200656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2202431101","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.978579,0.00044550846,0.0005148145,0.003741916,0.009551611,0.0010837591,0.000029580604,0.00031153896,0.0057422663],"genre_scores_gemma":[0.9882157,0.00007722468,0.00063946366,0.00637822,0.0020130898,0.00024212786,0.000043837135,0.00004513008,0.0023452246],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9949817,0.002143201,0.0010978117,0.00079366006,0.00023949014,0.00074413855],"domain_scores_gemma":[0.9972755,0.0008894474,0.00036558553,0.00045347135,0.00033821448,0.00067782885],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0044070943,0.00034848833,0.0006427452,0.0001579309,0.0003908496,0.00009217428,0.00036953692,0.0012542648,0.0006640747],"category_scores_gemma":[0.002331662,0.00034298032,0.00024972603,0.00040453975,0.0010474967,0.00030435747,0.00024827803,0.0022441219,0.0011637309],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0069427984,0.0106252,0.25935465,0.0001800288,0.0006511999,0.00049284083,0.0024302446,0.00075014436,0.016278984,0.004566753,0.016641153,0.681086],"study_design_scores_gemma":[0.010706942,0.0031564028,0.09730236,0.000035166348,0.00031690387,0.0001490708,0.00012587044,0.0064567598,0.027320884,0.0105419215,0.84290475,0.0009829947],"about_ca_topic_score_codex":0.0000325951,"about_ca_topic_score_gemma":0.000066401626,"teacher_disagreement_score":0.82626355,"about_ca_system_score_codex":0.00029753824,"about_ca_system_score_gemma":0.00042665255,"threshold_uncertainty_score":0.99990225},"labels":[],"label_agreement":null},{"id":"W2205608260","doi":"10.1021/acs.chemrestox.5b00137","title":"The Role of CD8 T Cells in Amodiaquine-Induced Liver Injury in PD1–/– Mice Cotreated with Anti-CTLA-4","year":2015,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Cytotoxic T cell; Chemistry; Pharmacology; Amodiaquine; Liver injury; CD8; CTLA-4; Cancer research; Medicine; Biochemistry; Immunology; In vitro; Immune system","score_opus":0.23478458164385996,"score_gpt":0.47097079237269623,"score_spread":0.23618621072883628,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2205608260","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904075,0.00031604487,0.0000011396286,0.0008794742,0.0002461305,0.00115197,0.000018609435,0.000028271346,0.0069508306],"genre_scores_gemma":[0.9989178,0.00030485357,0.000049960767,0.00017099464,0.000099709934,0.00033271252,0.00000985967,0.000029066245,0.00008505391],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9946766,0.0024932171,0.000642111,0.0005392975,0.0004338014,0.0012149652],"domain_scores_gemma":[0.99670255,0.0022125014,0.00013207596,0.0003212017,0.0002813804,0.00035027362],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.004925297,0.0002535943,0.0005088719,0.00057265244,0.0001101417,0.00002069841,0.0006661543,0.0010426976,0.00007227778],"category_scores_gemma":[0.0008975646,0.00020358419,0.00005348008,0.0017157277,0.00086206023,0.00014352113,0.00028576085,0.0036669397,0.00009600492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002702028,0.0009883575,0.021867363,0.000045606404,0.000028211747,0.00016262766,0.00093738537,0.00012548272,0.9586993,0.00044288402,0.00024190797,0.013758842],"study_design_scores_gemma":[0.002860787,0.0006062306,0.001680116,0.000054655222,0.000007926746,0.000017864697,0.00057130895,0.0030562016,0.98192316,0.0024591044,0.006549357,0.00021330666],"about_ca_topic_score_codex":0.00095532526,"about_ca_topic_score_gemma":0.0010827517,"teacher_disagreement_score":0.023223836,"about_ca_system_score_codex":0.0006632135,"about_ca_system_score_gemma":0.0006136582,"threshold_uncertainty_score":0.99863166},"labels":[],"label_agreement":null},{"id":"W2214265996","doi":"10.1007/s00216-015-9202-4","title":"An in vitro metabolomics approach to identify hepatotoxicity biomarkers in human L02 liver cells treated with pekinenal, a natural compound","year":2015,"lang":"en","type":"article","venue":"Analytical and Bioanalytical Chemistry","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Key Research and Development Program of China; Six Talent Peaks Project in Jiangsu Province; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China","keywords":"Metabolomics; Arachidonic acid; Chemistry; Apoptosis; Pharmacology; Biochemistry; Cell; Fatty acid; Intracellular; In vitro; Biology; Enzyme; Chromatography","score_opus":0.10198396777583457,"score_gpt":0.39264609812442497,"score_spread":0.2906621303485904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2214265996","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994928,0.00013002165,0.00014702142,0.00025686747,0.00004865696,0.0004343663,0.000044720193,0.00006342316,0.0039469404],"genre_scores_gemma":[0.99847436,0.00002400733,0.00044812434,0.00059403956,0.0001257604,0.00003887173,0.00007710702,0.000025016863,0.00019271743],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972592,0.00032432843,0.00056430564,0.0008183171,0.0003253431,0.0007085078],"domain_scores_gemma":[0.9984139,0.00015054006,0.00008826149,0.00027989707,0.0001172343,0.0009501684],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010533318,0.0004199789,0.0006635893,0.00022594069,0.0001310332,0.00009575175,0.0003177001,0.00059152103,0.00006792661],"category_scores_gemma":[0.00008323509,0.0003476815,0.0001079993,0.0009968117,0.00049758283,0.00020581644,0.00011243656,0.001365091,0.000019319847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025756236,0.0021795328,0.015489906,0.00015820187,0.00031386744,0.00032420072,0.0002636174,0.00023707733,0.97726256,0.00019959598,0.00012623912,0.0008696078],"study_design_scores_gemma":[0.003914765,0.00021409013,0.0044620507,0.00003604593,0.00039607132,0.000121197416,0.00047387168,0.22497639,0.7630686,0.00034963113,0.0011114832,0.00087577465],"about_ca_topic_score_codex":0.00063553813,"about_ca_topic_score_gemma":0.000119552555,"teacher_disagreement_score":0.22473931,"about_ca_system_score_codex":0.00023930645,"about_ca_system_score_gemma":0.00008875624,"threshold_uncertainty_score":0.99989754},"labels":[],"label_agreement":null},{"id":"W2223803148","doi":"10.1007/s00535-015-1131-7","title":"An analysis of drug-induced liver injury, which showed histological findings similar to autoimmune hepatitis","year":2015,"lang":"en","type":"article","venue":"Journal of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Alberta Innovates - Health Solutions","keywords":"Hepatology; Medicine; Abdominal surgery; Liver injury; Colorectal surgery; Autoimmune hepatitis; Surgical oncology; Drug; Internal medicine; Hepatitis; Gastroenterology; Pathology; Pharmacology","score_opus":0.10314022121899784,"score_gpt":0.3996062454286742,"score_spread":0.2964660242096763,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2223803148","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993678,0.000049362872,0.0017795163,0.0022848237,0.0017412095,0.00026247828,0.00004955263,0.00003135881,0.000123713],"genre_scores_gemma":[0.99648094,0.000067848276,0.0008680343,0.0022800488,0.0002091715,0.000013693516,0.0000142819545,0.000019877509,0.000046089426],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99596596,0.0017033498,0.0011141961,0.0003124128,0.0003518513,0.0005522456],"domain_scores_gemma":[0.99728596,0.00016337118,0.0007555082,0.00028284892,0.00089776615,0.00061455905],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002739395,0.00027986875,0.0011006598,0.0011264248,0.00012868507,0.000018116996,0.00060658326,0.0004606955,0.0004615955],"category_scores_gemma":[0.00042445047,0.00025785048,0.000339933,0.00081074686,0.00013131194,0.0002784748,0.00011310561,0.00129636,0.000025752926],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009932673,0.0014861069,0.7933405,0.000027604146,0.002337848,0.00020187939,0.0045188228,0.006379858,0.17591518,0.00012795524,0.002872087,0.0028594928],"study_design_scores_gemma":[0.0056837755,0.020094577,0.88040334,0.00004513221,0.0044205827,0.0005432905,0.0006540792,0.023555225,0.05405128,0.000256227,0.009791746,0.0005007395],"about_ca_topic_score_codex":0.00021726279,"about_ca_topic_score_gemma":0.0012531577,"teacher_disagreement_score":0.12186391,"about_ca_system_score_codex":0.00033637835,"about_ca_system_score_gemma":0.00014338084,"threshold_uncertainty_score":0.99998736},"labels":[],"label_agreement":null},{"id":"W2224371296","doi":"10.1097/pec.0000000000000665","title":"Are Recommended Doses of Acetaminophen Effective for Children Aged 2 to 3 Years? A Pharmacokinetic Modeling Answer","year":2015,"lang":"en","type":"article","venue":"Pediatric Emergency Care","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre; Montreal General Hospital; University of Toronto","funders":"","keywords":"Medicine; Dose; Dosing; Pharmacokinetics; Elixir (programming language); Acetaminophen; Antipyretic; Plasma concentration; Anesthesia; Pharmacology; Analgesic","score_opus":0.1445210430770942,"score_gpt":0.4290177610632098,"score_spread":0.28449671798611564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2224371296","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98950493,0.0022155372,0.0010982974,0.00014359235,0.0034445517,0.002709984,0.00038899985,0.00011223098,0.0003818594],"genre_scores_gemma":[0.9965607,0.00036956987,0.00039048263,0.00024408865,0.0015159994,0.0006812554,0.0000780848,0.00004578491,0.00011404898],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99796516,0.0004196886,0.00049235247,0.00044110327,0.00021901481,0.00046269386],"domain_scores_gemma":[0.9985934,0.00012131549,0.00028921076,0.00021205001,0.0004296904,0.00035436574],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00062932156,0.00027641325,0.00038840837,0.00028055522,0.00016359586,0.0000072738626,0.00029890065,0.00032182233,0.00024394097],"category_scores_gemma":[0.00034810713,0.00029954955,0.0002029451,0.000572616,0.000016975633,0.00012101693,0.000099156074,0.0005255013,0.00006000216],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003747924,0.0012274203,0.6755863,0.0015309101,0.0009744443,0.000025293799,0.040785894,0.09205611,0.019339168,0.000061325154,0.08742835,0.07723685],"study_design_scores_gemma":[0.06500886,0.0071898727,0.5306231,0.00020013486,0.0122625865,0.00008243309,0.020282391,0.04740173,0.25097644,0.006557769,0.050030623,0.009384083],"about_ca_topic_score_codex":0.00009826386,"about_ca_topic_score_gemma":0.000055339046,"teacher_disagreement_score":0.23163728,"about_ca_system_score_codex":0.00014152269,"about_ca_system_score_gemma":0.000077282144,"threshold_uncertainty_score":0.99994564},"labels":[],"label_agreement":null},{"id":"W2240173975","doi":"10.1111/bcp.12885","title":"Mechanism of isoniazid‐induced hepatotoxicity: then and now","year":2016,"lang":"en","type":"review","venue":"British Journal of Clinical Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":216,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"University of California, San Diego; Canada Research Chairs","keywords":"Idiosyncrasy; Liver injury; Isoniazid; Metabolite; Immune system; Drug; Medicine; Mechanism (biology); Liver failure; Phenotype; Pharmacology; Tuberculosis; Immunology; Biology; Internal medicine; Pathology; Biochemistry; Gene","score_opus":0.3268997492706442,"score_gpt":0.5460942300265794,"score_spread":0.21919448075593523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2240173975","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012422294,0.9683328,0.00018432055,0.00036466328,0.015490475,0.0015606814,0.00034893482,0.000052342635,0.0012434792],"genre_scores_gemma":[0.0071990592,0.98646414,0.00016530996,0.0011518635,0.0044463133,0.00006354996,0.000008103377,0.000110546935,0.00039112873],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9857406,0.0070316433,0.0052779303,0.00070278905,0.00045057185,0.0007964348],"domain_scores_gemma":[0.9872965,0.0053444174,0.0056509497,0.0002471976,0.000600983,0.00085990434],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0092343725,0.00070034154,0.005417581,0.00048111068,0.00028496183,0.000043085412,0.0010412529,0.0031959738,0.0018959566],"category_scores_gemma":[0.0011740021,0.00062698766,0.0018306264,0.00036516786,0.00070309604,0.00031215406,0.00037160233,0.0064634886,0.00014026687],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034597033,0.00080158585,0.000034898167,0.0031614322,0.002063422,0.0009068891,0.000040605057,5.355625e-7,0.00057536823,0.00023211262,0.005537464,0.9862997],"study_design_scores_gemma":[0.004301553,0.0011013256,0.000029387413,0.005560098,0.0031721701,0.0061311563,0.000012616104,0.00002896638,0.0011362741,0.0018468439,0.9760623,0.00061728497],"about_ca_topic_score_codex":0.00002063923,"about_ca_topic_score_gemma":0.000015971918,"teacher_disagreement_score":0.9856824,"about_ca_system_score_codex":0.00013991093,"about_ca_system_score_gemma":0.0011816311,"threshold_uncertainty_score":0.9996182},"labels":[],"label_agreement":null},{"id":"W2244509338","doi":"10.1139/cjpp-2014-0085","title":"Hepatoprotective effects of early pentoxifylline administration on hepatic injury induced by concanavalin A in rat","year":2014,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Pentoxifylline; Liver injury; Malondialdehyde; Internal medicine; Medicine; Hepatocyte; Fibrosis; Saline; Concanavalin A; Endocrinology; Tumor necrosis factor alpha; Necrosis; Inflammation; Pharmacology; Oxidative stress; Chemistry; Biochemistry","score_opus":0.039402360846326895,"score_gpt":0.3649412713471885,"score_spread":0.3255389105008616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2244509338","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99584574,0.00023943477,0.00003890038,0.00064737565,0.0023955198,0.0005934485,0.000032417112,0.000008205862,0.00019897181],"genre_scores_gemma":[0.9974442,0.00011634315,0.00002208768,0.0019852247,0.00032408306,0.000044997603,0.000008667687,0.000019317846,0.00003508056],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99647915,0.0020085003,0.00066015177,0.0002779865,0.00009634167,0.0004778874],"domain_scores_gemma":[0.9978008,0.0008429095,0.0005512805,0.00010436217,0.00016785847,0.00053274765],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010618914,0.00026560086,0.00062920136,0.00048725947,0.0001883797,0.000008135612,0.0002351766,0.0006276241,0.00040031294],"category_scores_gemma":[0.00020861757,0.00026283588,0.000101120364,0.00027695321,0.0003520493,0.00014380916,0.000017884062,0.0016329242,0.000012581934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013576305,0.00019736454,0.004000497,0.0002031967,0.00014714985,0.000044782497,0.00075173186,0.000045932316,0.98425484,0.0005006218,0.0005897745,0.007906489],"study_design_scores_gemma":[0.0029391116,0.0043888823,0.00618105,0.000058178677,0.0001238304,0.00003488247,0.00002760758,0.000464162,0.9786405,0.0024895442,0.0044195782,0.00023269205],"about_ca_topic_score_codex":0.0016072675,"about_ca_topic_score_gemma":0.001974967,"teacher_disagreement_score":0.007673797,"about_ca_system_score_codex":0.00015381647,"about_ca_system_score_gemma":0.000605446,"threshold_uncertainty_score":0.99998236},"labels":[],"label_agreement":null},{"id":"W2252629962","doi":"","title":"Is chronic poisoning with acetaminophen in children a frequent occurrence in Toronto?","year":2001,"lang":"en","type":"article","venue":"PubMed","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Medicine; Acetaminophen; Liver transplantation; Pediatrics; Acetylcysteine; Ingestion; Population; Retrospective cohort study; Internal medicine; Transplantation; Anesthesia; Environmental health","score_opus":0.09309726362971898,"score_gpt":0.3726262445264587,"score_spread":0.2795289808967397,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2252629962","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9855782,0.001354053,0.000028037486,0.0005062304,0.00032013154,0.0016371673,0.000028137449,0.00006909355,0.0104789995],"genre_scores_gemma":[0.9962026,0.00053730997,0.000024851353,0.00083361816,0.00016696697,0.0019908326,0.000016304126,0.00001380346,0.00021371608],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99812335,0.00028854606,0.00029696393,0.00039110883,0.00014647937,0.00075352757],"domain_scores_gemma":[0.99945784,0.00007175427,0.00010368123,0.00017830009,0.000024567924,0.00016385758],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007701432,0.00021217432,0.00024137525,0.00012106692,0.000108012915,0.000023565868,0.00023501096,0.00029124194,0.00045056653],"category_scores_gemma":[0.000036922454,0.00020280288,0.000043691358,0.00035985984,0.00008021098,0.0003327411,0.000050671442,0.00086300506,0.00004147753],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002054753,0.0002446799,0.7077419,0.000018671213,0.00005481233,0.000036774967,0.0007751509,0.0002535861,0.00027251462,0.00008694108,0.00011181926,0.29019767],"study_design_scores_gemma":[0.002926321,0.000073662326,0.9806948,0.000025120162,0.000028712295,0.00008039921,0.00009091997,0.000565803,0.0054456457,0.00011482522,0.0096239755,0.00032984783],"about_ca_topic_score_codex":0.0032136196,"about_ca_topic_score_gemma":0.009062583,"teacher_disagreement_score":0.28986785,"about_ca_system_score_codex":0.0011754825,"about_ca_system_score_gemma":0.000082696555,"threshold_uncertainty_score":0.82700616},"labels":[],"label_agreement":null},{"id":"W2262358356","doi":"10.7019/tpj.200912.0107","title":"Prevention and Monitoring of Hepatotoxicity among Patients Receiving Antituberculosis Medications","year":2009,"lang":"en","type":"article","venue":"Zhōnghuá yàoxué zázhì","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"","keywords":"Medicine; Internal medicine; Alanine aminotransferase; Logistic regression; Liver function; Liver function tests; Gastroenterology","score_opus":0.07712865594885832,"score_gpt":0.4060506405183619,"score_spread":0.3289219845695036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2262358356","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99319357,0.00018673445,0.0002911739,0.00028124359,0.0008266179,0.0006379026,0.000021813374,0.00011491983,0.0044460227],"genre_scores_gemma":[0.9983657,0.0005395987,0.00046566693,0.00012908004,0.00020343692,0.00004369459,0.000022823666,0.0000162074,0.00021381729],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981701,0.00038094452,0.000496161,0.00035274605,0.0002515958,0.00034847617],"domain_scores_gemma":[0.99895656,0.00015630898,0.00029594894,0.0002218538,0.00015807868,0.00021126877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007760433,0.000216292,0.0003040176,0.00019339669,0.00039143077,0.000021341428,0.00018182429,0.00041637075,0.00012727987],"category_scores_gemma":[0.00018444151,0.00022942705,0.00010357354,0.00035209573,0.00016086374,0.00037102815,0.000054135206,0.0007129486,0.000019628855],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000066410146,0.0006515441,0.86347574,0.00007380266,0.000102695005,0.000002130202,0.0008242585,0.000048385064,0.032024283,0.0004373598,0.00014419103,0.10214917],"study_design_scores_gemma":[0.0010420696,0.0002476221,0.84212697,0.00012199069,0.00013967858,0.000003596961,0.00008084572,0.00070811063,0.15257213,0.0014758012,0.0012369837,0.000244213],"about_ca_topic_score_codex":0.00009173966,"about_ca_topic_score_gemma":0.00003312302,"teacher_disagreement_score":0.120547846,"about_ca_system_score_codex":0.00008491967,"about_ca_system_score_gemma":0.000047017715,"threshold_uncertainty_score":0.9355764},"labels":[],"label_agreement":null},{"id":"W2272028191","doi":"","title":"HEPATOMA MCARDLE-RH7777 CELLS HAVE THE SAME RESPONSE AS NORMAL RAT HEPATOCYTES TO BOTH DIBUTYRYL-CAMP AND ANTICALMODULIN W-7","year":2002,"lang":"en","type":"article","venue":"The Medical Journal of The Islamic Republic of Iran","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medical journal; Medicine; Internal medicine; Endocrinology; Family medicine","score_opus":0.07566780664629266,"score_gpt":0.36351747440122834,"score_spread":0.2878496677549357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2272028191","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9280387,0.0005738683,0.00015200322,0.06756895,0.0019845294,0.0006117479,0.000016135193,0.000022466127,0.0010315921],"genre_scores_gemma":[0.98954076,0.0006304124,0.00005365241,0.007827255,0.00065054145,0.000012961834,4.5309753e-7,0.000027788756,0.0012562012],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9929817,0.004015065,0.0010626726,0.0002598278,0.0011196765,0.00056108274],"domain_scores_gemma":[0.99552846,0.002676894,0.00065166905,0.00056867744,0.00020862793,0.00036569982],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.009648402,0.0003011127,0.00057087507,0.00016740858,0.0006397039,0.00007249642,0.0015151084,0.00045043003,0.0015863812],"category_scores_gemma":[0.003076893,0.00014954149,0.00036248844,0.00042889203,0.0010673965,0.0001977055,0.0003851029,0.0026192965,0.00007050148],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.020354021,0.003224767,0.016737273,0.00037597536,0.0029426536,0.0010620737,0.0489722,0.0010740496,0.53173023,0.0051277312,0.061827354,0.30657166],"study_design_scores_gemma":[0.010390781,0.0034997861,0.02021559,0.0007986556,0.0012430119,0.010591724,0.0028664637,0.040445223,0.6473304,0.013663351,0.24772376,0.0012312678],"about_ca_topic_score_codex":0.0000839897,"about_ca_topic_score_gemma":0.000040504066,"teacher_disagreement_score":0.30534038,"about_ca_system_score_codex":0.00009870381,"about_ca_system_score_gemma":0.00020812934,"threshold_uncertainty_score":0.9996817},"labels":[],"label_agreement":null},{"id":"W2274397026","doi":"10.4103/0974-777x.170499","title":"Tuberculous drug-induced liver injury and treatment re-challenge in Human Immunodeficiency Virus co-infection","year":2015,"lang":"en","type":"article","venue":"Journal of Global Infectious Diseases","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Lachine Hospital","funders":"","keywords":"Medicine; Discontinuation; Tuberculosis; Interquartile range; Regimen; Adverse effect; Internal medicine; Incidence (geometry); Retrospective cohort study; Human immunodeficiency virus (HIV); Liver injury; Pediatrics; Immunology; Pathology","score_opus":0.12351448743389508,"score_gpt":0.4354963782139361,"score_spread":0.311981890780041,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2274397026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902633,0.0022753675,0.000014217753,0.0001624714,0.0014413513,0.00043105028,0.0000680751,0.0000736561,0.0052705524],"genre_scores_gemma":[0.99738294,0.0019361526,0.000004705163,0.00021852725,0.0003797984,0.000027596874,0.000005904447,0.000016675069,0.000027677283],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9977368,0.00075853016,0.0006124706,0.0002562656,0.00025666226,0.00037925493],"domain_scores_gemma":[0.9986817,0.00009843215,0.00041321348,0.00014507516,0.0002211521,0.00044038947],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006619138,0.00030061585,0.0004518668,0.0002196258,0.00030464068,0.000059549413,0.00011370786,0.000301868,0.0000945901],"category_scores_gemma":[0.00013018379,0.0002736456,0.00018938618,0.0003361725,0.00013062447,0.00042075117,0.000045365225,0.000589241,0.000035633428],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021981949,0.009459645,0.8198942,0.00012106101,0.00063853734,0.00077617774,0.0027200428,0.0014459435,0.018097728,0.0013479193,0.002230519,0.14107004],"study_design_scores_gemma":[0.03378419,0.022856932,0.79775053,0.00042092823,0.0024006094,0.0030536007,0.0016012102,0.001917612,0.033663232,0.021074152,0.078701906,0.0027750921],"about_ca_topic_score_codex":0.002332667,"about_ca_topic_score_gemma":0.0018967967,"teacher_disagreement_score":0.13829495,"about_ca_system_score_codex":0.0014663498,"about_ca_system_score_gemma":0.00026948255,"threshold_uncertainty_score":0.99997157},"labels":[],"label_agreement":null},{"id":"W2275249722","doi":"10.1177/0960327114565494","title":"Global research productivity of <i>N</i> -acetylcysteine use in paracetamol overdose","year":2015,"lang":"en","type":"article","venue":"Human & Experimental Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"An-Najah National University","keywords":"Gross domestic product; Per capita; Productivity; Interquartile range; Population; Medicine; Index (typography); Socioeconomics; Toxicology; Environmental health; Demography; Geography; Business; Agricultural economics; Economic growth; Economics; Surgery; Sociology","score_opus":0.5554391971595649,"score_gpt":0.557290340154713,"score_spread":0.0018511429951481029,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2275249722","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9838776,0.0004001722,0.000012110564,0.0002288633,0.0011751278,0.0013992784,0.000026679409,0.0000897194,0.012790475],"genre_scores_gemma":[0.99788,0.000012197003,0.00017241843,0.00033207893,0.0002985266,0.0003329386,0.000025270332,0.000028941447,0.00091763696],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99469095,0.002735439,0.0006498088,0.0006866854,0.00037573252,0.0008614027],"domain_scores_gemma":[0.99853593,0.00023347845,0.0002083963,0.00044426028,0.00021069114,0.00036726703],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0028711043,0.00030849443,0.0005650054,0.00030348523,0.0002764654,0.000029716228,0.00040035197,0.0006686981,0.00058289646],"category_scores_gemma":[0.00030547992,0.00033478867,0.00010622553,0.0008345771,0.0008442504,0.00044713024,0.00036922592,0.0008947683,0.00020457833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016809223,0.0045585274,0.07571526,0.000055071174,0.00008272411,0.00013277504,0.0024619026,0.00045049938,0.8956103,0.014190708,0.0022711172,0.002790212],"study_design_scores_gemma":[0.0058313883,0.0020356697,0.009901458,0.000027958698,0.000022515278,0.000110101326,0.0011492153,0.00023295004,0.9405768,0.0029539212,0.036728177,0.00042986806],"about_ca_topic_score_codex":0.0008006314,"about_ca_topic_score_gemma":0.0010906837,"teacher_disagreement_score":0.0658138,"about_ca_system_score_codex":0.0009472392,"about_ca_system_score_gemma":0.00023176477,"threshold_uncertainty_score":0.9999104},"labels":[],"label_agreement":null},{"id":"W2287158478","doi":"10.1016/j.jemermed.2015.12.004","title":"Outcomes of Patients With Premature Discontinuation of the 21-h Intravenous N-Acetylcysteine Protocol After Acute Acetaminophen Overdose","year":2016,"lang":"en","type":"article","venue":"Journal of Emergency Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; University of Alberta; Statistics Canada; University of Calgary; Centre Hospitalier Universitaire Sainte-Justine; Queen's University; Alberta Health Services","funders":"","keywords":"Medicine; Acetaminophen; Acetylcysteine; acetaminophen overdose; Discontinuation; Cohort; Retrospective cohort study; Ingestion; Incidence (geometry); Confidence interval; Liver injury; Anesthesia; Alanine aminotransferase; Internal medicine; Antidote; Toxicity","score_opus":0.05446926779444853,"score_gpt":0.39633714435820055,"score_spread":0.341867876563752,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2287158478","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9859416,0.000050000777,0.0002340035,0.0017799842,0.0019304024,0.009648363,0.000044115426,0.0000062675813,0.00036525272],"genre_scores_gemma":[0.9975354,0.000049203452,0.000058034435,0.00009545548,0.00030100901,0.00090786436,0.0000015132852,0.00001642748,0.0010350621],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9978158,0.0003608086,0.0010267529,0.00012407053,0.00047427774,0.0001982818],"domain_scores_gemma":[0.9974353,0.00010359536,0.0015771845,0.00020949561,0.00057117024,0.000103305516],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007915566,0.00019170395,0.0005027791,0.000117558186,0.00006527232,0.0000010321079,0.00026656364,0.00019818643,0.0016835281],"category_scores_gemma":[0.0002757297,0.00008038368,0.00014501342,0.00025131207,0.00017059049,0.0002106357,0.00004579111,0.00045450914,0.0000024136932],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006903554,0.0014642257,0.83064663,0.00037122905,0.0013491946,0.000008999318,0.0031086183,0.000028388291,0.14028156,0.00011943315,0.002139104,0.013579083],"study_design_scores_gemma":[0.011603685,0.0034025996,0.8864043,0.0006526123,0.0008520081,0.0000129607815,0.00009464371,0.000014719539,0.082251854,0.00040360948,0.014105333,0.00020168799],"about_ca_topic_score_codex":0.000010114586,"about_ca_topic_score_gemma":0.000024080553,"teacher_disagreement_score":0.058029696,"about_ca_system_score_codex":0.000055975943,"about_ca_system_score_gemma":0.00008891758,"threshold_uncertainty_score":0.9992291},"labels":[],"label_agreement":null},{"id":"W2295140952","doi":"10.1139/cjpp-2016-0071","title":"Hepatoprotective effect of <i>trans</i>-Chalcone on experimentally induced hepatic injury in rats: inhibition of hepatic inflammation and fibrosis","year":2016,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"University Grants Commission; University of the Punjab; McGill University","keywords":"TBARS; Carbon tetrachloride; Chemistry; Chalcone; Liver injury; Hepatic fibrosis; Fibrosis; Inflammation; Internal medicine; Bilirubin; Endocrinology; Oxidative stress; Pharmacology; Hepatic stellate cell; Lipid peroxidation; Biochemistry; Medicine","score_opus":0.032985194477588305,"score_gpt":0.343519064602601,"score_spread":0.3105338701250127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2295140952","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99763846,0.0002829837,0.00002263433,0.0005185764,0.0007348032,0.0006494507,0.00006273569,0.0000061477926,0.000084208004],"genre_scores_gemma":[0.99912834,0.00037112035,0.00001779287,0.00025021902,0.0001515609,0.00005497497,0.000003733338,0.000015951302,0.0000062793115],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996972,0.0016445664,0.00071678846,0.0002368745,0.000086889595,0.00034283803],"domain_scores_gemma":[0.9981437,0.00075773225,0.00057834055,0.000086005704,0.00013611272,0.0002981544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010791324,0.00024590502,0.0006556214,0.00061221374,0.00013119672,0.000003660103,0.00011199541,0.00048730805,0.0004622754],"category_scores_gemma":[0.0000952101,0.00019486225,0.00009308412,0.00021943563,0.000504278,0.00022147494,0.000021080936,0.00066540844,0.0000032111266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019255414,0.00006722968,0.009500247,0.00030857258,0.00015871247,0.000021653299,0.0012785227,0.000026465252,0.9750502,0.00011583077,0.00003273826,0.011514246],"study_design_scores_gemma":[0.0034503809,0.0035238052,0.008174096,0.00020114437,0.00012052765,0.00003604158,0.000043355692,0.00008725537,0.98270154,0.0013115053,0.00018057034,0.00016976602],"about_ca_topic_score_codex":0.0006864328,"about_ca_topic_score_gemma":0.00048704,"teacher_disagreement_score":0.01134448,"about_ca_system_score_codex":0.00014572163,"about_ca_system_score_gemma":0.0002583079,"threshold_uncertainty_score":0.7946252},"labels":[],"label_agreement":null},{"id":"W2303148531","doi":"10.1021/acs.chemrestox.5b00317","title":"Identification of Acetaminophen Adducts of Rat Liver Microsomal Proteins using 2D-LC-MS/MS","year":2015,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Microsome; Chromatography; Tandem mass spectrometry; Acetaminophen; Drug metabolism; Mass spectrometry; Biochemistry; In vitro; Metabolism","score_opus":0.454446464140299,"score_gpt":0.5188481474651845,"score_spread":0.0644016833248855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2303148531","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955394,0.00041898573,0.00009336883,0.00047206803,0.000699686,0.001363392,0.00003379095,0.000029344747,0.0013499471],"genre_scores_gemma":[0.99856526,0.00008228417,0.00051960844,0.00008277193,0.0002434976,0.00017173696,0.000019514058,0.000027293545,0.000288063],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99547005,0.0017931204,0.0008944402,0.00051593065,0.0005068361,0.0008195978],"domain_scores_gemma":[0.99751174,0.0007740214,0.00031143468,0.00036846034,0.0006824131,0.00035193615],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0047276504,0.00021266559,0.0005033299,0.00049204065,0.000114443115,0.000014866988,0.0005880288,0.0010474169,0.00032264148],"category_scores_gemma":[0.0017977024,0.000223163,0.00009921625,0.00088101666,0.0012454946,0.00020290648,0.00036018982,0.0019430256,0.00009595172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008966071,0.0009237312,0.0022060242,0.00027549354,0.000047803518,0.000034508008,0.0010422386,0.00012923747,0.9897532,0.0007433582,0.0005081883,0.0034396267],"study_design_scores_gemma":[0.0017640752,0.00028921088,0.00044749348,0.000044908327,0.000025942141,0.000036335547,0.00017809156,0.004102513,0.98728454,0.0019237093,0.0037224062,0.00018079214],"about_ca_topic_score_codex":0.00022489109,"about_ca_topic_score_gemma":0.00005007188,"teacher_disagreement_score":0.003973276,"about_ca_system_score_codex":0.00052756077,"about_ca_system_score_gemma":0.00063802116,"threshold_uncertainty_score":0.91003233},"labels":[],"label_agreement":null},{"id":"W2313339563","doi":"10.1139/cjpp-2012-0255","title":"Modeling xenobiotic susceptibility to hepatotoxicity using an in vitro oxidative stress inflammation model","year":2013,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Pharmacology; Chemistry; Toxicity; Acetaldehyde; Inflammation; Oxidative stress; Hepatocyte; CYP2E1; Nimesulide; Biochemistry; In vitro; Ethanol; Biology; Immunology; Microsome","score_opus":0.11261603492810353,"score_gpt":0.3826783111341329,"score_spread":0.2700622762060294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2313339563","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99604416,0.000090423375,0.0015616987,0.00047161177,0.00090933015,0.0007709561,0.00006334452,0.000014157875,0.00007430344],"genre_scores_gemma":[0.99722135,0.000032381682,0.0007633525,0.0014804013,0.00042353413,0.000031460335,0.000014744128,0.00002172097,0.000011036784],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99691755,0.0012353128,0.0007008617,0.00037288983,0.000075105236,0.0006983014],"domain_scores_gemma":[0.9980466,0.00015467982,0.00024168192,0.00013651252,0.00035708543,0.0010634873],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001035816,0.00028366604,0.00052576064,0.0006312163,0.00037857916,0.00002575814,0.00031124987,0.00057992275,0.0009561148],"category_scores_gemma":[0.00008342011,0.00029107567,0.00008424132,0.00029902536,0.00025691712,0.00065209804,0.000044720677,0.001469249,0.000023164792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023985324,0.00008625682,0.0013502928,0.00005060968,0.00005617479,0.000016945625,0.0015073867,0.27498308,0.7202721,0.000059129707,0.00002491414,0.0013532364],"study_design_scores_gemma":[0.0007559253,0.00016177454,0.00054050185,0.000012266007,0.00005010377,0.000033612796,0.00017003059,0.48040918,0.5138791,0.0037653933,0.000032337735,0.00018974085],"about_ca_topic_score_codex":0.0051978617,"about_ca_topic_score_gemma":0.007733157,"teacher_disagreement_score":0.20639299,"about_ca_system_score_codex":0.0003640453,"about_ca_system_score_gemma":0.00076387957,"threshold_uncertainty_score":0.99995714},"labels":[],"label_agreement":null},{"id":"W2314078457","doi":"10.1016/j.freeradbiomed.2014.10.790","title":"Inflammation-Enhanced Drug-Induced Liver Injury","year":2014,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Superoxide; Oxidative stress; Superoxide dismutase; Reactive oxygen species; Myeloperoxidase; NADPH oxidase; Biochemistry; Pharmacology; Inflammation; Spin trapping; Horseradish peroxidase; Radical; Immunology; Enzyme; Biology","score_opus":0.06893965513377406,"score_gpt":0.40682262359623045,"score_spread":0.33788296846245636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2314078457","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96610665,0.0004702283,0.0022402424,0.010444338,0.0024542776,0.00048236156,0.00001764374,0.00018815324,0.017596098],"genre_scores_gemma":[0.9923593,0.00054440217,0.00014024226,0.0040220544,0.0021470597,0.00006703045,0.00004412762,0.000014674905,0.00066115236],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.997816,0.0008533386,0.00040169084,0.0003971672,0.000106210624,0.00042557815],"domain_scores_gemma":[0.99846584,0.00069576537,0.00014374379,0.00026877623,0.00006795347,0.0003579397],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015028788,0.0002404,0.000408348,0.00015664319,0.00040630228,0.0000053033664,0.00025740944,0.00071314065,0.0010264454],"category_scores_gemma":[0.0011053402,0.00018964638,0.000051118568,0.0001931376,0.00083067134,0.00009191863,0.00009656696,0.0011247623,0.000147389],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034938162,0.00008057251,0.0019561495,0.00007080658,0.000095281386,0.00000680125,0.0008831547,0.00000221578,0.49103722,0.0314115,0.0055962154,0.46851072],"study_design_scores_gemma":[0.0047900146,0.0010123008,0.004671518,0.00007556801,0.00015797795,0.000046575526,0.00008042098,0.0019146451,0.27412137,0.030627929,0.68204796,0.00045371713],"about_ca_topic_score_codex":0.00012216828,"about_ca_topic_score_gemma":0.00007909037,"teacher_disagreement_score":0.67645174,"about_ca_system_score_codex":0.000036996116,"about_ca_system_score_gemma":0.000040695668,"threshold_uncertainty_score":0.99988675},"labels":[],"label_agreement":null},{"id":"W2314154236","doi":"10.1021/tx500108u","title":"IgG<sub>3</sub> Is the Dominant Subtype of Anti-isoniazid Antibodies in Patients with Isoniazid-Induced Liver Failure","year":2014,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Isoniazid; Antibody; Liver injury; Medicine; Isotype; Immunology; Immune system; Pharmacology; Pathology; Tuberculosis; Monoclonal antibody","score_opus":0.11768585683787106,"score_gpt":0.41562512986974637,"score_spread":0.2979392730318753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2314154236","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943921,0.00008218669,0.000013050312,0.003075646,0.000288767,0.0013255884,0.000027316311,0.000027626067,0.0007677196],"genre_scores_gemma":[0.9986762,0.00016784981,0.0000625065,0.0006855962,0.00014439605,0.00019003263,0.000015181562,0.000037447666,0.000020808098],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9947143,0.0021151525,0.0006448749,0.0006886392,0.00056718866,0.0012697966],"domain_scores_gemma":[0.9963785,0.0023225287,0.00020609041,0.0004759216,0.00037975944,0.00023723485],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.003775851,0.00033022166,0.00065255,0.000498106,0.0002562404,0.000025414067,0.0007289143,0.0010697583,0.00015386762],"category_scores_gemma":[0.0011136504,0.00024588214,0.000102456164,0.0011674352,0.0010795405,0.00016353355,0.00036397047,0.0034820468,0.00012778796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013521658,0.0011573547,0.114742845,0.0001604677,0.000060490438,0.000025986546,0.001017182,0.000023299333,0.865577,0.000657776,0.0007535249,0.014471935],"study_design_scores_gemma":[0.003401715,0.0006912864,0.06820871,0.000087258464,0.000020879499,0.0000075401376,0.00010660317,0.0009206607,0.9215948,0.00082717696,0.0038612008,0.00027219308],"about_ca_topic_score_codex":0.00012680284,"about_ca_topic_score_gemma":0.00044036523,"teacher_disagreement_score":0.056017805,"about_ca_system_score_codex":0.0002991683,"about_ca_system_score_gemma":0.00024789645,"threshold_uncertainty_score":0.99999934},"labels":[],"label_agreement":null},{"id":"W2317482647","doi":"10.1093/toxsci/kfu195","title":"Glycodeoxycholic Acid Levels as Prognostic Biomarker in Acetaminophen-Induced Acute Liver Failure Patients","year":2014,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of Environmental Health Sciences; McGill University; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Alcohol Abuse and Alcoholism; National Center for Research Resources; National Institute of General Medical Sciences; U.S. Public Health Service","keywords":"Bile acid; Liver injury; Medicine; Acetaminophen; Biomarker; Gastroenterology; Internal medicine; Cholestasis; Pharmacology; Chemistry; Biochemistry","score_opus":0.2133717377522804,"score_gpt":0.4314479681390215,"score_spread":0.21807623038674107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2317482647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9839654,0.00003860622,0.00009479243,0.0013597636,0.0011563177,0.0011325722,0.00002172755,0.0001822344,0.01204856],"genre_scores_gemma":[0.99543756,0.00002719379,0.0004049896,0.0034781187,0.00012448973,0.00021849107,0.000008958826,0.000014791102,0.00028541553],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99562114,0.001409165,0.00053763203,0.0008824625,0.0004941422,0.001055438],"domain_scores_gemma":[0.9983914,0.00068089156,0.00022724338,0.00021545537,0.00009857284,0.0003864379],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0023680117,0.00039178386,0.00044783414,0.0002763305,0.0007846973,0.00010924121,0.00082322926,0.0009065255,0.0019798244],"category_scores_gemma":[0.0010509937,0.0003025007,0.00013347625,0.0011894674,0.0007036367,0.00045937565,0.0002541439,0.0011501535,0.0011372017],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004401433,0.003043237,0.16184017,0.0000622137,0.0001408794,0.00013941729,0.0014052213,0.00015579144,0.5686283,0.007994761,0.0007692519,0.25538057],"study_design_scores_gemma":[0.0039558704,0.0028903165,0.814322,0.000056280656,0.00012830604,0.00007387901,0.0001276426,0.008194624,0.13079304,0.006821967,0.0314975,0.0011386084],"about_ca_topic_score_codex":0.000055774904,"about_ca_topic_score_gemma":0.00015909979,"teacher_disagreement_score":0.6524818,"about_ca_system_score_codex":0.00016429211,"about_ca_system_score_gemma":0.00011226872,"threshold_uncertainty_score":0.9999427},"labels":[],"label_agreement":null},{"id":"W2323066310","doi":"10.1097/der.0000000000000074","title":"Hepatitis Due to Mycophenolate Mofetil Used to Treat Atopic Dermatitis and Allergic Contact Dermatitis","year":2014,"lang":"en","type":"letter","venue":"Dermatitis","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; Galderma; U.S. Department of Veterans Affairs","keywords":"Medicine; Mycophenolate; Dermatology; Atopic dermatitis; Allergic contact dermatitis; Contact dermatitis; Allergy; Immunology; Surgery","score_opus":0.07591863336288815,"score_gpt":0.3488501161640162,"score_spread":0.272931482801128,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2323066310","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.26921296,0.0006027469,0.0031048895,0.70382154,0.0045616073,0.004267478,0.0015964853,0.0007651772,0.012067095],"genre_scores_gemma":[0.3162806,0.0007533442,0.00048120428,0.6761608,0.0024479225,0.00096152135,0.0006348523,0.00018897654,0.0020907903],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99288833,0.0018881266,0.0014173654,0.0013019807,0.00071386277,0.0017903423],"domain_scores_gemma":[0.9962925,0.000962444,0.00053640944,0.0009146625,0.0002631202,0.0010308792],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"category_scores_codex":[0.0005302892,0.0013338864,0.0017823082,0.0008643083,0.0009866975,0.00037812104,0.0008406084,0.002633639,0.0027998588],"category_scores_gemma":[0.00020534263,0.0014991559,0.0003588927,0.00061862555,0.00016782625,0.0004805141,0.00037347525,0.0040727286,0.0036279368],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008702043,0.000069585476,0.003049409,0.001162344,0.0003128297,0.0027293076,0.0036411094,0.00009232889,0.0003674392,0.00013337273,0.97025275,0.018180797],"study_design_scores_gemma":[0.0019774127,0.000293786,0.026630005,0.00043217963,0.00032232085,0.001991168,0.000034391094,0.0007442666,0.0062733074,0.00068261934,0.959013,0.0016055317],"about_ca_topic_score_codex":0.0032148063,"about_ca_topic_score_gemma":0.0023914578,"teacher_disagreement_score":0.047067635,"about_ca_system_score_codex":0.0005367743,"about_ca_system_score_gemma":0.00019065452,"threshold_uncertainty_score":0.99994123},"labels":[],"label_agreement":null},{"id":"W2329528883","doi":"10.1021/tx500013z","title":"Mild Isoniazid-Induced Liver Injury in Humans Is Associated with an Increase in Th17 Cells and T Cells Producing IL-10","year":2014,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Liver injury; Isoniazid; Immune system; Medicine; Rash; Tuberculosis; Immunology; Inflammation; Pharmacology; Internal medicine; Pathology","score_opus":0.2037744442395053,"score_gpt":0.45940700522170946,"score_spread":0.25563256098220416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2329528883","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995452,0.000049373968,0.0000025697234,0.0009648927,0.00019048227,0.0012648065,0.000038970826,0.000054425138,0.0019824805],"genre_scores_gemma":[0.9977923,0.00013478269,0.00009192054,0.0011287935,0.00017954478,0.00033617194,0.00002082972,0.000046158995,0.00026951896],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99272996,0.0037496474,0.0006057273,0.0010813961,0.00039216946,0.0014411213],"domain_scores_gemma":[0.99690485,0.0019139231,0.00013183273,0.0004012675,0.00016962709,0.00047851368],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.007308219,0.0003455747,0.0006203186,0.0008323805,0.00021167485,0.00004610127,0.000488942,0.0014141866,0.00053135277],"category_scores_gemma":[0.0011990123,0.0003447094,0.00004589266,0.0011855685,0.0006013353,0.0002751786,0.00030169167,0.0045426963,0.0000899322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017462219,0.0016783982,0.0100677945,0.00011554602,0.000029727233,0.00014979423,0.0024338507,0.000035472563,0.9739896,0.00012980646,0.00059597916,0.009027776],"study_design_scores_gemma":[0.0034888766,0.0012044389,0.007548116,0.00013351574,0.0000150818805,0.000007230733,0.00015603026,0.0058599804,0.9762132,0.0012618185,0.003672167,0.00043950602],"about_ca_topic_score_codex":0.0009023262,"about_ca_topic_score_gemma":0.0023374218,"teacher_disagreement_score":0.00858827,"about_ca_system_score_codex":0.0006882165,"about_ca_system_score_gemma":0.00028712978,"threshold_uncertainty_score":0.9999005},"labels":[],"label_agreement":null},{"id":"W2333638932","doi":"10.1177/171516350413700907","title":"Non-Prescription Painkillers and Chronic Liver Disease","year":2004,"lang":"en","type":"article","venue":"Canadian Pharmacists Journal / Revue des Pharmaciens du Canada","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medical prescription; Chronic liver disease; Liver disease; Disease; Medicine; Internal medicine; Pharmacology; Cirrhosis","score_opus":0.0783874840616613,"score_gpt":0.3338100969984067,"score_spread":0.2554226129367454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2333638932","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9881566,0.002821455,0.00032263587,0.0005283851,0.0055252723,0.00087020156,0.00039980598,0.000070062655,0.0013055602],"genre_scores_gemma":[0.9799476,0.012309737,0.000083556064,0.005093191,0.0018487398,0.00005949407,0.00004190059,0.00006863576,0.0005471439],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967776,0.00034934512,0.00058241305,0.00056738424,0.00035897744,0.0013642695],"domain_scores_gemma":[0.994509,0.000091578724,0.00026001083,0.0002319128,0.0003290282,0.004578517],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001026139,0.00051309523,0.0003807449,0.00045872922,0.0021220741,0.00019126869,0.00051157933,0.00022705822,0.001252598],"category_scores_gemma":[0.00014149657,0.0005731222,0.00016956704,0.0005171674,0.00040575897,0.00065916264,0.00006838432,0.0019977062,0.00006367247],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":true,"about_ca_system_consensus":true,"study_design_scores_codex":[0.001431788,0.00046520802,0.009828138,0.001646612,0.0012402092,0.20583557,0.0069174315,0.05533617,0.07981216,0.000978627,0.028830048,0.60767806],"study_design_scores_gemma":[0.015779672,0.0003244231,0.0011310888,0.00015869117,0.0011070187,0.35111588,0.000047886046,0.037742388,0.04492024,0.0020872168,0.5425078,0.0030776593],"about_ca_topic_score_codex":0.026285144,"about_ca_topic_score_gemma":0.12824444,"teacher_disagreement_score":0.60460037,"about_ca_system_score_codex":0.005487319,"about_ca_system_score_gemma":0.005717006,"threshold_uncertainty_score":0.99991965},"labels":[],"label_agreement":null},{"id":"W2334422212","doi":"10.1097/00024382-200406002-00194","title":"ETHYL PYRUVATE MODULATES HEPATIC INFLAMMATION DURING EARLY SEPSIS.","year":2004,"lang":"en","type":"article","venue":"Shock","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Inflammation; Sepsis; Chemistry; Pharmacology; Medicine; Internal medicine","score_opus":0.07016178268855429,"score_gpt":0.37666195242070466,"score_spread":0.3065001697321504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2334422212","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932383,0.00008461817,0.00043520724,0.0010636039,0.0009816323,0.0005278281,0.000012080416,0.0002857968,0.0033709428],"genre_scores_gemma":[0.99811274,0.00008256371,0.00027313505,0.0003658626,0.00043663525,0.000054904485,0.000015890399,0.000030012452,0.0006282814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985439,0.00021175364,0.00034332633,0.000299455,0.00016615247,0.00043538684],"domain_scores_gemma":[0.9993608,0.00007014214,0.00013321443,0.00019916572,0.000072286675,0.0001644063],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004084684,0.00021815917,0.00021020223,0.00014691216,0.00046208003,0.000038487084,0.0001724439,0.00042945152,0.00038119513],"category_scores_gemma":[0.000072909206,0.00022843122,0.0001015302,0.00027464004,0.00007629788,0.000309045,0.0000607247,0.00085692975,0.0010422319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002401845,0.00012791101,0.010170902,0.00017728351,0.0001639269,0.000048479338,0.0035731974,0.021142198,0.9457516,0.0015626692,0.000044283184,0.016997354],"study_design_scores_gemma":[0.0019931155,0.00010140973,0.036255226,0.00004466922,0.000070799244,0.00001531697,0.000056691722,0.0019561455,0.9398366,0.0145708425,0.0047319345,0.00036721968],"about_ca_topic_score_codex":0.00023773396,"about_ca_topic_score_gemma":0.00011197178,"teacher_disagreement_score":0.026084322,"about_ca_system_score_codex":0.00020959596,"about_ca_system_score_gemma":0.00006118536,"threshold_uncertainty_score":0.9997356},"labels":[],"label_agreement":null},{"id":"W2339130443","doi":"10.1021/acs.chemrestox.6b00098","title":"Protein Targets of Isoniazid-Reactive Metabolites in Mouse Liver<i>in Vivo</i>","year":2016,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Chemistry; Isoniazid; Peptide; Lysine; In vivo; Biochemistry; Biology; Tuberculosis; Medicine; Amino acid","score_opus":0.22621007793322565,"score_gpt":0.479620994400111,"score_spread":0.2534109164668854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2339130443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907216,0.0004792002,0.000018006345,0.0024536264,0.00016385746,0.0015726236,0.00007171707,0.00003258333,0.004486785],"genre_scores_gemma":[0.997391,0.0004098362,0.00019291694,0.0002022125,0.00011258661,0.0008744357,0.0000032667276,0.000028958764,0.00078477955],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9945002,0.0024343012,0.0007338675,0.00066100986,0.00036594455,0.0013046596],"domain_scores_gemma":[0.99645716,0.0026675698,0.00013438432,0.00029219358,0.00017855772,0.00027014996],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0044390173,0.00025431058,0.0006128028,0.00091737,0.000063894644,0.000008489737,0.00055383315,0.0011258094,0.0009904488],"category_scores_gemma":[0.0024859002,0.00021364584,0.00009300224,0.0010912162,0.0008887912,0.00023499197,0.00030716942,0.0024463858,0.00011741613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013338072,0.0013922888,0.00937781,0.00011242488,0.000026215428,0.00013843857,0.00050545513,0.000008999252,0.9717549,0.0036699704,0.00015945699,0.011520212],"study_design_scores_gemma":[0.0029810953,0.0002134877,0.0009404504,0.00009746329,0.0000044500835,0.000008648476,0.00009465871,0.00027775392,0.9769295,0.0062325797,0.011999862,0.0002200511],"about_ca_topic_score_codex":0.00037975961,"about_ca_topic_score_gemma":0.00067108497,"teacher_disagreement_score":0.011840405,"about_ca_system_score_codex":0.00071666314,"about_ca_system_score_gemma":0.0003220284,"threshold_uncertainty_score":0.99992275},"labels":[],"label_agreement":null},{"id":"W2339366025","doi":"","title":"A Mundane Situation Punctuated by Sudden Rash and Liver Failure: Unexpected, Unintended Clinical Consequences","year":2006,"lang":"en","type":"article","venue":"University of Toronto Medical Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Rash; Unintended consequences; Law and economics; Punctuated equilibrium; Medicine; Political science; Sociology; Law; Dermatology; Biology; Evolutionary biology","score_opus":0.058642171237474755,"score_gpt":0.3642790754309129,"score_spread":0.30563690419343814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2339366025","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9817593,0.0015918482,0.0039763623,0.0055418485,0.0009231991,0.00029053062,0.000036300033,0.0000764172,0.0058041634],"genre_scores_gemma":[0.99577785,0.00237401,0.0003995687,0.00034307697,0.0002710325,2.420804e-7,0.000022891629,0.000006782695,0.0008045534],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99776006,0.0010107438,0.00037279262,0.0002124932,0.0003812105,0.00026270104],"domain_scores_gemma":[0.9986234,0.00037486936,0.00030177567,0.00007537741,0.00021133381,0.00041324977],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015280239,0.00014710365,0.0003013367,0.00004509179,0.00042735785,0.00001915008,0.00025907,0.0006088218,0.0060949964],"category_scores_gemma":[0.00028657282,0.00014450055,0.00011687655,0.00006327697,0.0011897382,0.00030779737,0.00007345778,0.0010599854,0.000019426245],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0043559773,0.003323766,0.040479504,0.00018515173,0.0017895765,0.0027873153,0.008072713,0.000065175285,0.12226627,0.0070596947,0.35868898,0.45092586],"study_design_scores_gemma":[0.023106959,0.0015994419,0.04619468,0.0003272355,0.0012148974,0.0028853787,0.00997119,0.015893828,0.013809595,0.0038243763,0.87983876,0.0013336394],"about_ca_topic_score_codex":0.007759518,"about_ca_topic_score_gemma":0.011907246,"teacher_disagreement_score":0.5211498,"about_ca_system_score_codex":0.0001801814,"about_ca_system_score_gemma":0.00026917263,"threshold_uncertainty_score":0.9988479},"labels":[],"label_agreement":null},{"id":"W2339416640","doi":"10.1139/cjpp-2016-0029","title":"Effects of <i>Rhus tripartitum</i> fruit extract on CCl<sub>4</sub>-induced hepatotoxicity and cisplatin-induced nephrotoxicity in rats","year":2016,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Malondialdehyde; Chemistry; Nephrotoxicity; Antioxidant; Pharmacology; Uric acid; Kidney; Cisplatin; Biochemistry; Toxicity; Endocrinology; Medicine; Internal medicine","score_opus":0.05307688877644869,"score_gpt":0.339933392797517,"score_spread":0.2868565040210683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2339416640","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949248,0.0004112806,0.000018804574,0.00092404854,0.0025040845,0.0009596706,0.00005072129,0.00001750708,0.00018907654],"genre_scores_gemma":[0.9963138,0.0006225009,0.000017865364,0.0024481337,0.000479612,0.00006766297,0.0000022868662,0.000033130327,0.000014969313],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9955486,0.0019519904,0.0009616652,0.00050108857,0.00014704198,0.00088960887],"domain_scores_gemma":[0.99588615,0.0020294746,0.0007436031,0.00016176757,0.00019322807,0.000985762],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013908354,0.00045953554,0.0009963665,0.00074233906,0.00034529675,0.000012076341,0.00032176953,0.0010057563,0.00030411422],"category_scores_gemma":[0.00028518602,0.00037949745,0.00017333995,0.00035928996,0.00057458656,0.00031810926,0.000051960953,0.0017943212,0.000022200626],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013692665,0.0002892451,0.0043407814,0.00022669906,0.00023812131,0.0003177434,0.00046503087,0.000021550708,0.9667073,0.00023966175,0.000417972,0.025366645],"study_design_scores_gemma":[0.0056748907,0.0014246928,0.029470678,0.00012587619,0.00017345397,0.00016546492,0.000022750499,0.000102022415,0.959255,0.001983077,0.0012343475,0.0003677558],"about_ca_topic_score_codex":0.00037252696,"about_ca_topic_score_gemma":0.0018605747,"teacher_disagreement_score":0.025129898,"about_ca_system_score_codex":0.00023091974,"about_ca_system_score_gemma":0.00074799603,"threshold_uncertainty_score":0.9998657},"labels":[],"label_agreement":null},{"id":"W2340802999","doi":"10.1016/j.jphotobiol.2016.03.027","title":"Hepatoprotective effect of grape seed oil against carbon tetrachloride induced oxidative stress in liver of γ-irradiated rat","year":2016,"lang":"en","type":"article","venue":"Journal of Photochemistry and Photobiology B Biology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":94,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Atomic Energy of Canada Limited","keywords":"Carbon tetrachloride; Oxidative stress; Chemistry; Antioxidant; CYP2E1; Liver injury; CCL4; Glutathione; Pharmacology; Biochemistry; Metabolism; Biology; Cytochrome P450; Enzyme","score_opus":0.03994424848283807,"score_gpt":0.3525531089571527,"score_spread":0.31260886047431463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2340802999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975864,0.0006163344,0.0000062413583,0.00006469177,0.0006483084,0.00041601472,0.0001294617,0.000012703166,0.00051982043],"genre_scores_gemma":[0.9983748,0.0012632769,0.000020514723,0.000074360265,0.00014263915,0.00006427729,0.000012964554,0.000016064056,0.000031074916],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966166,0.0014814276,0.0010327908,0.00035593758,0.000089759946,0.00042348626],"domain_scores_gemma":[0.9965363,0.0015630082,0.0012647081,0.00018520784,0.0002786884,0.00017206714],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0017542831,0.0003588944,0.0010564586,0.00029847393,0.00007073008,0.0000028604684,0.00030962247,0.0013056613,0.00007900445],"category_scores_gemma":[0.0006569682,0.00024749682,0.00019943048,0.00031171224,0.0006830143,0.000091348105,0.00008318737,0.0012691995,0.000001166843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0041973707,0.00023328238,0.09261716,0.00022013101,0.0003194996,0.00005004008,0.0004633577,0.000006028414,0.8918185,0.000013645426,0.000003015568,0.010057937],"study_design_scores_gemma":[0.00466389,0.002032128,0.005518204,0.00022108453,0.000108114145,0.00015503689,0.00009997822,0.00006726101,0.9864923,0.00020146456,0.00019974425,0.00024084415],"about_ca_topic_score_codex":0.00017347473,"about_ca_topic_score_gemma":0.000046367422,"teacher_disagreement_score":0.094673716,"about_ca_system_score_codex":0.000118529104,"about_ca_system_score_gemma":0.00016394137,"threshold_uncertainty_score":0.99999774},"labels":[],"label_agreement":null},{"id":"W2345256664","doi":"10.1080/15563650.2016.1175006","title":"Massive acetaminophen overdose: effect of hemodialysis on acetaminophen and acetylcysteine kinetics","year":2016,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Hemodialysis; Acetaminophen; Medicine; Metabolic acidosis; Context (archaeology); Acetylcysteine; Anesthesia; Antidote; Toxicity; Surgery; Internal medicine; Chemistry","score_opus":0.13078130389081086,"score_gpt":0.4621253566217752,"score_spread":0.33134405273096434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2345256664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883346,0.00019587553,0.00033842016,0.0036109113,0.0023968674,0.0010147791,0.0000997029,0.000110292305,0.0038985722],"genre_scores_gemma":[0.99479276,0.0006390845,0.00016205013,0.0016913579,0.0007105351,0.00012461297,0.000010176726,0.000044133638,0.0018252913],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9937403,0.003395637,0.0011600469,0.0008064419,0.00023575901,0.0006618065],"domain_scores_gemma":[0.9892826,0.009042745,0.000585767,0.00052335876,0.00012638507,0.00043912162],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0027133538,0.0004490268,0.0012382212,0.00020760008,0.00017929681,0.000012165789,0.0003975205,0.0016369215,0.00094160606],"category_scores_gemma":[0.0028190266,0.00031203756,0.00035357446,0.00028802807,0.0011877995,0.00011815892,0.0002825898,0.0010915595,0.0003201634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0042446405,0.0011292759,0.05127813,0.0001891675,0.000653828,0.0000709162,0.00015498827,0.00006248638,0.5818418,0.0020424908,0.002001102,0.35633114],"study_design_scores_gemma":[0.018110467,0.014702931,0.03191716,0.00012257765,0.0009150336,0.000051069605,0.000028527431,0.00042092495,0.8562481,0.0018602975,0.07483162,0.0007912978],"about_ca_topic_score_codex":0.0000066689126,"about_ca_topic_score_gemma":0.000013521459,"teacher_disagreement_score":0.35553983,"about_ca_system_score_codex":0.0001336943,"about_ca_system_score_gemma":0.000068158486,"threshold_uncertainty_score":0.9999717},"labels":[],"label_agreement":null},{"id":"W2394571710","doi":"10.5588/ijtld.15.0450","title":"&lt;I&gt;CYP7A1&lt;/I&gt;, &lt;I&gt;BAAT&lt;/I&gt; and &lt;I&gt;UGT1A1&lt;/I&gt; polymorphisms and susceptibility to anti-tuberculosis drug-induced hepatotoxicity","year":2016,"lang":"en","type":"article","venue":"The International Journal of Tuberculosis and Lung Disease","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Natural Science Foundation of China; National Science Foundation","keywords":"Haplotype; Genotype; Odds ratio; Tuberculosis; Medicine; Genotyping; Internal medicine; Genetics; Biology; Gene; Pathology","score_opus":0.03331327502129527,"score_gpt":0.33020248749271197,"score_spread":0.2968892124714167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2394571710","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9623511,0.00691178,0.00024674294,0.022805441,0.0033485375,0.001666073,0.0011151573,0.00015635774,0.001398825],"genre_scores_gemma":[0.9849492,0.0074473987,0.0001388562,0.003957161,0.0020287875,0.00015862945,0.000049446026,0.00014678937,0.0011237821],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99102694,0.0019904005,0.0021486464,0.0015138142,0.0018777702,0.0014424527],"domain_scores_gemma":[0.992533,0.001645743,0.0012595423,0.0009164705,0.0012421387,0.0024030823],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0044866162,0.0012936321,0.0014531016,0.0009394515,0.001447615,0.00047601742,0.0015821919,0.0008065971,0.0012691562],"category_scores_gemma":[0.0010209939,0.0009796799,0.0008678654,0.00063725037,0.0010233483,0.0013907724,0.0009466655,0.0014038034,0.000118251286],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003303498,0.0015967734,0.017865995,0.00021459903,0.002295927,0.00028702157,0.0014224539,0.00015723081,0.9336477,0.004511273,0.010768704,0.023928834],"study_design_scores_gemma":[0.020539356,0.0018457071,0.47350174,0.002222794,0.0062035713,0.0018340305,0.00020077423,0.013107982,0.18867338,0.0087311035,0.27783525,0.005304334],"about_ca_topic_score_codex":0.000052942334,"about_ca_topic_score_gemma":0.00062202243,"teacher_disagreement_score":0.7449743,"about_ca_system_score_codex":0.00086347724,"about_ca_system_score_gemma":0.00053128507,"threshold_uncertainty_score":0.9999815},"labels":[],"label_agreement":null},{"id":"W2401048437","doi":"10.1136/bmj.i2579","title":"Treatments for paracetamol poisoning","year":2016,"lang":"en","type":"article","venue":"BMJ","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Computer science; Medical emergency; World Wide Web; Data science","score_opus":0.24987704256515536,"score_gpt":0.5031959633268228,"score_spread":0.25331892076166745,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2401048437","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9573504,0.00013574689,0.0060846433,0.0118229035,0.002699485,0.0024488075,0.00013247681,0.00024650813,0.019079084],"genre_scores_gemma":[0.98587406,0.000047571364,0.00066017447,0.0010652911,0.0006217061,0.00070231734,0.0000073292363,0.000019506157,0.011002044],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989984,0.0001754815,0.0002121883,0.00021701487,0.00007108378,0.0003258425],"domain_scores_gemma":[0.999236,0.0003650689,0.000103400474,0.00013564885,0.0000456713,0.00011421034],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053776003,0.00013200732,0.00014751728,0.000053876196,0.00026029116,0.000009786006,0.000104416795,0.0002504752,0.00052515185],"category_scores_gemma":[0.00014773181,0.00009272283,0.00009790228,0.00006947528,0.00004980391,0.00012098028,0.0000225532,0.00014531263,0.0005084081],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00089788844,0.0003649093,0.01864017,0.00004051371,0.0004905815,0.000020965213,0.00045784962,0.000032548553,0.3196556,0.004224444,0.03285861,0.6223159],"study_design_scores_gemma":[0.0043138512,0.00025901056,0.0044175233,0.000037474747,0.00016259606,0.000033674023,0.000035791913,0.00047786048,0.35125893,0.0037640182,0.6349439,0.00029535437],"about_ca_topic_score_codex":0.000011152663,"about_ca_topic_score_gemma":0.0000102693,"teacher_disagreement_score":0.62202054,"about_ca_system_score_codex":0.000085820866,"about_ca_system_score_gemma":0.000041776468,"threshold_uncertainty_score":0.6534727},"labels":[],"label_agreement":null},{"id":"W2401983585","doi":"10.1097/meg.0000000000000524","title":"Risperidone-induced hepatotoxicity in a patient addicted to synthetic cannabinoid","year":2016,"lang":"en","type":"letter","venue":"European Journal of Gastroenterology & Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Alberta Innovates - Health Solutions","keywords":"Medicine; Risperidone; Cannabinoid; Family medicine; Internal medicine; General surgery; Gastroenterology; Schizophrenia (object-oriented programming); Psychiatry","score_opus":0.061382654148909775,"score_gpt":0.33941064316239844,"score_spread":0.2780279890134887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2401983585","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7059122,0.00012399601,0.00037174363,0.28390685,0.0065451856,0.0009324375,0.00023407993,0.000081951956,0.0018915854],"genre_scores_gemma":[0.61617184,0.0001712446,0.0002123905,0.38019773,0.0028296618,0.000057337864,0.000029100916,0.00017048274,0.00016019549],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.97808737,0.015323882,0.0028355478,0.0010600804,0.000526193,0.0021669595],"domain_scores_gemma":[0.9953572,0.00051303254,0.0021925012,0.000738953,0.00053050567,0.0006678061],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.003147618,0.0010788961,0.0021871915,0.001967013,0.0002608431,0.000037421552,0.0015441343,0.0016408277,0.0010473813],"category_scores_gemma":[0.00047690092,0.0009501755,0.00066729623,0.00042969687,0.00047175356,0.00021086886,0.0004829502,0.010338628,0.0007656306],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010806737,0.0007882533,0.034836736,0.00027764306,0.0012917946,0.070344485,0.0017075385,0.0001200605,0.031997353,0.000013529384,0.8160511,0.03176476],"study_design_scores_gemma":[0.0042097955,0.0070865024,0.0014130223,0.00032289326,0.0002846952,0.00853049,0.000042055413,0.000062891326,0.0045510177,0.00005204552,0.9728207,0.0006238854],"about_ca_topic_score_codex":0.00006875004,"about_ca_topic_score_gemma":0.00025556562,"teacher_disagreement_score":0.15676959,"about_ca_system_score_codex":0.0007978279,"about_ca_system_score_gemma":0.0003612856,"threshold_uncertainty_score":0.9998658},"labels":[],"label_agreement":null},{"id":"W2402000540","doi":"10.1007/s40262-016-0408-1","title":"Neonatal Maturation of Paracetamol (Acetaminophen) Glucuronidation, Sulfation, and Oxidation Based on a Parent–Metabolite Population Pharmacokinetic Model","year":2016,"lang":"en","type":"article","venue":"Clinical Pharmacokinetics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; American Foundation for Pharmaceutical Education; National Center for Advancing Translational Sciences; Howard Hughes Medical Institute","keywords":"Glucuronidation; Pharmacokinetics; Acetaminophen; Metabolite; Urine; Population; Sulfation; Pharmacology; NONMEM; Gestational age; Chemistry; Gestation; Medicine; Endocrinology; Pregnancy; Biochemistry; Microsome; Biology","score_opus":0.1707557073575224,"score_gpt":0.4667549812125988,"score_spread":0.2959992738550764,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2402000540","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94686866,0.00020258922,0.046685576,0.0022046878,0.0017747529,0.0012483664,0.00021958715,0.00016820783,0.0006275551],"genre_scores_gemma":[0.9945728,0.0009451845,0.0012386992,0.0019688427,0.0005417628,0.000109083114,0.00024389043,0.000052153984,0.0003275928],"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9957809,0.0011188682,0.0014854667,0.00070553663,0.0004566299,0.00045263895],"domain_scores_gemma":[0.9968812,0.0012186433,0.0008028993,0.00035821376,0.00038788223,0.0003512018],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0017584023,0.00041486067,0.0005331576,0.00028563885,0.0002487025,0.00003377373,0.00026556494,0.0005220101,0.00042013547],"category_scores_gemma":[0.000658169,0.00034576046,0.00018775788,0.00038594246,0.00032429522,0.0004403067,0.000075605196,0.00072569423,0.00007613579],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040469673,0.0013799274,0.040596694,0.0002923708,0.00024529203,0.000008511148,0.0002566516,0.055698734,0.31098914,0.003914107,0.0014403666,0.5811312],"study_design_scores_gemma":[0.010002591,0.00045207917,0.07768363,0.00011192919,0.0005962246,0.000008556105,0.000015949074,0.70939964,0.18132971,0.0028833884,0.016822029,0.0006942566],"about_ca_topic_score_codex":0.0000101930345,"about_ca_topic_score_gemma":0.000004160868,"teacher_disagreement_score":0.65370095,"about_ca_system_score_codex":0.00009933249,"about_ca_system_score_gemma":0.000095254276,"threshold_uncertainty_score":0.99989945},"labels":[],"label_agreement":null},{"id":"W2402839106","doi":"10.1016/j.jhep.2016.05.015","title":"Hepatotoxicity and potential drug interaction with ledipasvir/sofosbuvir in HIV/HCV infected patients","year":2016,"lang":"en","type":"letter","venue":"Journal of Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"","keywords":"Ledipasvir; Sofosbuvir; Medicine; Human immunodeficiency virus (HIV); Drug; Virology; Hepatitis C; Hepatitis C virus; Pharmacology; Ribavirin; Virus","score_opus":0.04292842468139775,"score_gpt":0.3523988969439312,"score_spread":0.30947047226253344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2402839106","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8723624,0.00015737118,0.00018816933,0.12197682,0.0036683795,0.0006791921,0.00008827606,0.000045418623,0.0008339904],"genre_scores_gemma":[0.8846783,0.0005236696,0.00013332047,0.11056232,0.0034046741,0.000044537246,0.00006689725,0.000086726584,0.00049958244],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9945433,0.0022852526,0.0013585327,0.0005356644,0.0004394848,0.00083772297],"domain_scores_gemma":[0.9965112,0.0007203294,0.0018095821,0.00024884584,0.00048993324,0.00022009212],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0010977562,0.0006279949,0.0012604527,0.0011558682,0.00022334138,0.000044935172,0.00039783353,0.002335387,0.00049846334],"category_scores_gemma":[0.00020067744,0.0004795609,0.00023538643,0.00030752068,0.0003848951,0.00057922624,0.00013886837,0.00796157,0.000080741505],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037373868,0.0006581939,0.4963636,0.00035262117,0.0008784983,0.0034834985,0.00071035436,0.00006251043,0.0023823509,0.000028490458,0.47380286,0.01753962],"study_design_scores_gemma":[0.008611355,0.0010499066,0.007593638,0.0003992743,0.00049449375,0.002398252,0.000036667934,0.00034241885,0.0061747665,0.0006637349,0.97134966,0.00088586484],"about_ca_topic_score_codex":0.0000886252,"about_ca_topic_score_gemma":0.0001753279,"teacher_disagreement_score":0.49754676,"about_ca_system_score_codex":0.0004914395,"about_ca_system_score_gemma":0.0003362557,"threshold_uncertainty_score":0.99976563},"labels":[],"label_agreement":null},{"id":"W240506283","doi":"10.1016/j.neubiorev.2015.04.015","title":"Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review","year":2015,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":457,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"MaRS","funders":"","keywords":"Psychiatry; Medicine; Riluzole; Bipolar disorder; Anxiety; Schizophrenia (object-oriented programming); Autism; Psychology; Disease; Amyotrophic lateral sclerosis; Lithium (medication); Internal medicine","score_opus":0.7463628515270129,"score_gpt":0.6562223458044436,"score_spread":0.09014050572256926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W240506283","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00013174093,0.9807368,0.0000059118097,0.000041123847,0.0050072633,0.013793996,0.0001340497,0.000049077444,0.000100019715],"genre_scores_gemma":[0.00002676049,0.995415,0.00007020214,0.002625412,0.00018501973,0.001535049,0.000022441935,0.00004923438,0.000070910755],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.96745837,0.022397134,0.00795561,0.0011665727,0.00040668732,0.0006155989],"domain_scores_gemma":[0.9929679,0.00015750587,0.0053685736,0.00088726636,0.00011919022,0.00049958966],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.054464176,0.00083448365,0.012037647,0.00044160328,0.00012565275,0.00003343626,0.0009588014,0.0013813467,0.00007167782],"category_scores_gemma":[0.008351547,0.00058282004,0.0014523837,0.0014836573,0.00063971675,0.00020661643,0.00028567694,0.003189531,0.00009486221],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012825239,0.00028726147,0.000100626836,0.44080898,0.0000010289991,0.000015442223,0.0000093214085,5.67769e-8,0.000013662921,0.000031886502,0.0007235679,0.5579953],"study_design_scores_gemma":[0.0004067307,0.00046313618,0.000008675247,0.19002533,0.0033082746,0.00018851514,0.0000023239145,0.000009510439,4.5155284e-7,0.000016235537,0.8052191,0.00035169977],"about_ca_topic_score_codex":0.000022027061,"about_ca_topic_score_gemma":0.00002434591,"teacher_disagreement_score":0.8044956,"about_ca_system_score_codex":0.00007268024,"about_ca_system_score_gemma":0.00073271047,"threshold_uncertainty_score":0.99991506},"labels":[],"label_agreement":null},{"id":"W2414882915","doi":"","title":"Medical prescription of heroin--a review.","year":2001,"lang":"en","type":"article","venue":"PubMed","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Saint-Luc","funders":"","keywords":"Heroin; Drug; Affect (linguistics); Medical prescription; Psychiatry; Medicine; Mental health; Intensive care medicine; Environmental health; Criminology; Pharmacology; Psychology","score_opus":0.1741635121426428,"score_gpt":0.4169874155199071,"score_spread":0.24282390337726428,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2414882915","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7478758,0.013532996,0.0006205369,0.014203783,0.0047030193,0.0043260623,0.00003043291,0.0003293912,0.21437795],"genre_scores_gemma":[0.9775201,0.013594045,0.000022679387,0.005483807,0.00031610398,0.0011224333,0.000011051396,0.000013136757,0.0019166054],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99837077,0.00044595634,0.0003674933,0.00019236529,0.00027923536,0.00034420541],"domain_scores_gemma":[0.9992603,0.00011306972,0.00013888848,0.00015917224,0.00007167726,0.00025691072],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0019075718,0.00011732798,0.00023171701,0.00006929442,0.000090130714,0.000004457077,0.00020346629,0.00033358048,0.0012518265],"category_scores_gemma":[0.00048293144,0.00011085296,0.000094157,0.0002620301,0.000105009975,0.000118122494,0.000046303096,0.0006132145,0.000094918716],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001714595,0.00034991186,0.008508266,0.00043911152,0.00008145428,0.000031088744,0.0000867548,0.000008899012,0.0011421553,0.00066393765,0.011866766,0.9766502],"study_design_scores_gemma":[0.0011540094,0.000042987816,0.053519182,0.000103987804,0.0001238716,0.00013294283,0.000018394547,0.00035498178,0.019146973,0.0007007643,0.92447776,0.00022412818],"about_ca_topic_score_codex":0.00002753176,"about_ca_topic_score_gemma":0.000024710174,"teacher_disagreement_score":0.97642606,"about_ca_system_score_codex":0.000049700597,"about_ca_system_score_gemma":0.000039238723,"threshold_uncertainty_score":0.99966115},"labels":[],"label_agreement":null},{"id":"W2417102958","doi":"10.1371/journal.pone.0157478","title":"Genetic Polymorphisms of Glutathione S-Transferase P1 (GSTP1) and the Incidence of Anti-Tuberculosis Drug-Induced Hepatotoxicity","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; St. Paul's Hospital","funders":"National Natural Science Foundation of China","keywords":"Medicine; Tuberculosis; Confounding; Prospective cohort study; Retrospective cohort study; Single-nucleotide polymorphism; Internal medicine; Genotype; Biology; Pathology; Genetics","score_opus":0.09135191904632585,"score_gpt":0.3256021026053526,"score_spread":0.23425018355902677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2417102958","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99502885,0.00047825114,0.00016627289,0.0024216254,0.00020327327,0.001095125,0.000111525296,0.000059964892,0.00043512092],"genre_scores_gemma":[0.9970583,0.0018197336,0.00025479836,0.00047643358,0.00012882664,0.0001182369,0.0000019303395,0.00002885396,0.00011292076],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99709743,0.001015128,0.0006912977,0.00038716124,0.00040910253,0.00039987566],"domain_scores_gemma":[0.99780184,0.0011376013,0.00030108614,0.0003790524,0.0001933438,0.000187103],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012955047,0.00027519808,0.00066283933,0.00015692197,0.0002575873,0.000010055813,0.00033258536,0.00035254902,0.0003108405],"category_scores_gemma":[0.00031009485,0.0001844081,0.00014689086,0.00033857606,0.000776262,0.00017806166,0.00011003963,0.0005641149,0.000032159594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00061507866,0.0011523626,0.03794308,0.00020413156,0.0004850935,0.0000078373005,0.0011000013,0.000005990284,0.95163476,0.0007389168,0.000018419523,0.006094309],"study_design_scores_gemma":[0.0034356667,0.00016329126,0.026507016,0.00024564122,0.000501904,0.000015004788,0.000045333745,0.00077563804,0.966671,0.001365196,0.000035506335,0.00023880362],"about_ca_topic_score_codex":0.00041114006,"about_ca_topic_score_gemma":0.000102918406,"teacher_disagreement_score":0.015036219,"about_ca_system_score_codex":0.000051906394,"about_ca_system_score_gemma":0.00009462659,"threshold_uncertainty_score":0.75199443},"labels":[],"label_agreement":null},{"id":"W2466464567","doi":"10.3109/1547691x.2016.1166167","title":"Exploring an animal model of amodiaquine-induced liver injury in rats and mice","year":2016,"lang":"en","type":"article","venue":"Journal of Immunotoxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Liver injury; Medicine; Glutathione; Amodiaquine; Hepatocyte; Pharmacology; Toxicity; Immune system; Internal medicine; Liver regeneration; Apoptosis; Endocrinology; Immunology; Chemistry; Biology; Biochemistry; Chloroquine; In vitro","score_opus":0.3561537694449966,"score_gpt":0.4217481464549879,"score_spread":0.06559437700999132,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2466464567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977378,0.00022195814,0.00017164333,0.00047783199,0.000875237,0.000300496,0.000016387501,0.000015895,0.00018274215],"genre_scores_gemma":[0.9975191,0.0014987098,0.00039118857,0.00030304608,0.00019504927,0.000031132357,5.304158e-7,0.00002402891,0.00003723412],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974692,0.000831952,0.0009058388,0.00022719742,0.00015852292,0.0004073073],"domain_scores_gemma":[0.99841493,0.0003834102,0.00064389576,0.00015903558,0.00021383633,0.00018489046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018337104,0.00022334108,0.00055598136,0.00052158086,0.00010487644,0.000009880451,0.00030401885,0.00046818823,0.000104777646],"category_scores_gemma":[0.00022602442,0.00017643253,0.00011176255,0.00020837739,0.00020328564,0.0009840135,0.00009890751,0.0009929208,0.0000095392625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027402972,0.00048613013,0.0025716498,0.0000358627,0.000081874336,0.000050834347,0.001189019,0.00013932791,0.94475967,0.00044369727,0.000024019591,0.047477614],"study_design_scores_gemma":[0.0029191275,0.0025617906,0.010971204,0.00009233808,0.00006982878,0.0002122274,0.00016938566,0.0027463571,0.9787408,0.00071237056,0.00055806525,0.00024648753],"about_ca_topic_score_codex":0.000030236919,"about_ca_topic_score_gemma":0.000041135492,"teacher_disagreement_score":0.047231127,"about_ca_system_score_codex":0.00016523543,"about_ca_system_score_gemma":0.00020522918,"threshold_uncertainty_score":0.719471},"labels":[],"label_agreement":null},{"id":"W2466633910","doi":"10.1097/fpc.0000000000000209","title":"HLA-DRB1*16","year":2016,"lang":"en","type":"article","venue":"Pharmacogenetics and Genomics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":79,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Daiichi Sankyo Europe; Menzies Centre for Australian Studies, King's College London, University of London; Medical Research Council; Shanghai Jiao Tong University; University of Nottingham; Universität Zürich; Newcastle University; King's College London; Daiichi-Sankyo; National Institute for Health and Care Research; Bundesinstitut für Arzneimittel und Medizinprodukte; McGill University; McGill University Health Centre; Nottingham University Hospitals NHS Trust; Wellcome Trust; Uppsala Universitet; Universidad de Málaga; Pfizer; Universidad Nacional de Rosario; GlaxoSmithKline; Helsingin ja Uudenmaan Sairaanhoitopiiri; Universiteit Utrecht; Sanofi; Amgen","keywords":"Odds ratio; Minor allele frequency; Genome-wide association study; Haplotype; Medicine; Population; Single-nucleotide polymorphism; Internal medicine; Allele; Genotype; Genetics; Biology","score_opus":0.13275525925313852,"score_gpt":0.4145607073128559,"score_spread":0.28180544805971736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2466633910","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98439354,0.0014285446,0.0019980203,0.0022179608,0.0017407406,0.00048543722,0.00014721145,0.00011635855,0.0074721635],"genre_scores_gemma":[0.98747027,0.0072677513,0.0003096502,0.0024414079,0.0006494186,0.000053641557,0.0000074314453,0.000042319272,0.0017581071],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99839056,0.00021848746,0.00033726185,0.00041621126,0.00012065173,0.0005168131],"domain_scores_gemma":[0.9990279,0.00020580049,0.0001212523,0.00018778043,0.00007728933,0.00037998718],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00057110854,0.00026768842,0.00022933159,0.00011071621,0.00035634372,0.00003222584,0.00021725488,0.00029120425,0.0009463746],"category_scores_gemma":[0.000035045105,0.00021388229,0.00008732355,0.00012467774,0.00021046934,0.00009306524,0.00014031805,0.00037750404,0.00035141615],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015407465,0.00009734893,0.0045084204,0.000026612237,0.000112550784,0.000010658119,0.0002087957,0.000047919137,0.6085807,0.0008584078,0.0015033402,0.38389114],"study_design_scores_gemma":[0.0015987983,0.00006843239,0.00070710527,0.000008099061,0.00009017231,0.000042986525,0.000020705795,0.00066941825,0.39091548,0.002291327,0.60328835,0.000299114],"about_ca_topic_score_codex":0.000016491109,"about_ca_topic_score_gemma":0.000015142197,"teacher_disagreement_score":0.601785,"about_ca_system_score_codex":0.00013451427,"about_ca_system_score_gemma":0.00007106944,"threshold_uncertainty_score":0.9999669},"labels":[],"label_agreement":null},{"id":"W2475245405","doi":"10.1139/cjpp-2016-0228","title":"Protective effect of <i>Trillium tschonoskii</i> saponin on CCl<sub>4</sub>-induced acute liver injury of rats through apoptosis inhibition","year":2016,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Wuhan University","keywords":"TUNEL assay; Apoptosis; Liver injury; Hepatocyte; Endocrinology; Internal medicine; Western blot; Medicine; Pharmacology; Saline; Chemistry; Necrosis; Andrology; Biochemistry; In vitro","score_opus":0.03968527719013091,"score_gpt":0.3434213360055241,"score_spread":0.3037360588153932,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2475245405","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99470055,0.00021144154,0.000079070516,0.0007474347,0.0028213481,0.00091322896,0.0002418329,0.000014656283,0.0002704335],"genre_scores_gemma":[0.9976031,0.0006295874,0.000019874919,0.0010944015,0.0005407105,0.000059194095,0.000006551601,0.000031371488,0.000015199345],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.995701,0.002360171,0.00080355286,0.00037896016,0.00013696228,0.0006193357],"domain_scores_gemma":[0.9968887,0.0010968593,0.0009947484,0.00015717196,0.00037082584,0.0004916929],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011202076,0.00039390931,0.0009351752,0.0005103065,0.00029806717,0.0000054992256,0.00025286313,0.00089140923,0.0005073148],"category_scores_gemma":[0.00014444075,0.00030053503,0.0002708791,0.000344579,0.0007768752,0.000337896,0.00004487002,0.0013616232,0.00003446272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004269091,0.00015510332,0.00031928485,0.0002036621,0.00077430985,0.000048619688,0.000537451,0.000028471246,0.97813094,0.00026615264,0.0017509508,0.0135159725],"study_design_scores_gemma":[0.0036227466,0.0056681205,0.00085556164,0.00012354986,0.0005202017,0.00009842339,0.0000192248,0.000017063752,0.9853659,0.0018206299,0.0016088736,0.00027965574],"about_ca_topic_score_codex":0.00026814837,"about_ca_topic_score_gemma":0.00019096397,"teacher_disagreement_score":0.013236317,"about_ca_system_score_codex":0.00020502805,"about_ca_system_score_gemma":0.0005990484,"threshold_uncertainty_score":0.9999447},"labels":[],"label_agreement":null},{"id":"W2479972342","doi":"10.1016/j.cyto.2016.07.010","title":"Necrotic cell death and suppression of T-cell immunity characterized acute liver failure due to drug-induced liver injury","year":2016,"lang":"en","type":"article","venue":"Cytokine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Alberta Innovates - Health Solutions","keywords":"Medicine; Liver injury; Gastroenterology; Autoimmune hepatitis; Internal medicine; Liver failure; Pathophysiology; Drug; Hepatic encephalopathy; Hepatitis; Pharmacology; Cirrhosis","score_opus":0.056829080682337836,"score_gpt":0.3418586137661191,"score_spread":0.28502953308378126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2479972342","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959741,0.00006363753,0.00022199024,0.00072856725,0.0007162598,0.0009946747,0.00026967732,0.00009571911,0.00093533826],"genre_scores_gemma":[0.9967574,0.00037152856,0.0004011531,0.00072306575,0.000194796,0.00008624617,0.000021797783,0.00004035021,0.0014036484],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978032,0.00067387614,0.00042663977,0.00043059612,0.00017687364,0.000488791],"domain_scores_gemma":[0.9985615,0.0003130399,0.00024725642,0.00037873603,0.00015265371,0.0003468017],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00063360366,0.00034013635,0.00048514985,0.00021216426,0.00030367592,0.000020413345,0.00031393074,0.0004882353,0.00094549224],"category_scores_gemma":[0.000059938164,0.00026340628,0.00011539942,0.00023166406,0.00010601876,0.00028734474,0.00029534005,0.0007357199,0.00028053045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010007637,0.0003675158,0.0011115217,0.0001377515,0.00006371769,0.000064195585,0.0009875337,7.716426e-7,0.9814615,0.000039795188,0.0007586603,0.014006246],"study_design_scores_gemma":[0.0024382635,0.00032341646,0.009525792,0.00008756408,0.00016706868,0.000037849288,0.000038426937,0.00011521839,0.968455,0.00007112547,0.018396936,0.0003433476],"about_ca_topic_score_codex":0.00011312711,"about_ca_topic_score_gemma":0.0000246282,"teacher_disagreement_score":0.017638275,"about_ca_system_score_codex":0.000086241525,"about_ca_system_score_gemma":0.0000734969,"threshold_uncertainty_score":0.9999818},"labels":[],"label_agreement":null},{"id":"W2480881576","doi":"10.1155/2016/3056438","title":"New Exploration of Chinese Herbal Medicines in Hepatology","year":2016,"lang":"en","type":"article","venue":"Evidence-based Complementary and Alternative Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Medical Research Council; Kidney Research UK","keywords":"Hepatology; Traditional medicine; Medicine; Internal medicine; Alternative medicine; Family medicine; Pathology","score_opus":0.3057904997673514,"score_gpt":0.4787354565706377,"score_spread":0.1729449568032863,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2480881576","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9231614,0.0014558688,0.015545687,0.05748198,0.0013149222,0.00064323796,0.00002725288,0.000036137953,0.0003335026],"genre_scores_gemma":[0.9944167,0.001158842,0.00027958455,0.0032313962,0.0007186865,0.00005125286,0.000018115505,0.000010867197,0.00011453264],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977854,0.0007125556,0.00061744323,0.00034782974,0.00025185078,0.0002849174],"domain_scores_gemma":[0.9977573,0.0015498035,0.00027002432,0.00015036194,0.00008754438,0.0001849601],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011845327,0.00023472459,0.00044509312,0.00029703422,0.00009964414,0.000002950292,0.00020717313,0.00009655604,0.002667295],"category_scores_gemma":[0.000347582,0.00014698567,0.000042080344,0.00031490592,0.0003850754,0.0005588053,0.000057110294,0.00030790048,0.000011917603],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019475599,0.00018310663,0.64054114,0.00016526996,0.00012920071,0.00007864269,0.0028068216,0.00009687382,0.1565714,0.00260304,0.0021925664,0.1926844],"study_design_scores_gemma":[0.06314695,0.011082782,0.20927668,0.007765738,0.0004917977,0.00011832365,0.0023015102,0.012856239,0.458997,0.1419819,0.09014317,0.0018378872],"about_ca_topic_score_codex":0.0016547149,"about_ca_topic_score_gemma":0.00093290803,"teacher_disagreement_score":0.43126443,"about_ca_system_score_codex":0.00010096846,"about_ca_system_score_gemma":0.000105835585,"threshold_uncertainty_score":0.9982444},"labels":[],"label_agreement":null},{"id":"W2507139442","doi":"10.4238/gmr.15038296","title":"Association between TXNRD1 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in a prospective study","year":2016,"lang":"en","type":"article","venue":"Genetics and Molecular Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"National Natural Science Foundation of China","keywords":"International HapMap Project; Medicine; Tuberculosis; Haplotype; Single-nucleotide polymorphism; Immunology; Genotype; Biology; Genetics; Pathology; Gene","score_opus":0.1367909917891106,"score_gpt":0.4507206955370955,"score_spread":0.3139297037479849,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2507139442","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99431586,0.00040546342,0.00004368491,0.0026730776,0.00012295705,0.0017990553,0.000059765258,0.00002793123,0.0005521862],"genre_scores_gemma":[0.99843454,0.0008171866,0.00002511721,0.00012133532,0.00008751617,0.00022482683,0.0000033192448,0.000030818737,0.0002553559],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962619,0.0015972919,0.00032811493,0.0006208706,0.0004990138,0.0006928191],"domain_scores_gemma":[0.9987529,0.0003964021,0.00011216726,0.00026994557,0.00019429385,0.0002743259],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003403432,0.00021687236,0.00031566067,0.00027142037,0.000579932,0.000102469516,0.00021888949,0.00040031745,0.000040094204],"category_scores_gemma":[0.00031553136,0.0001875314,0.00004362567,0.00033205445,0.00017616476,0.00010210534,0.0003598918,0.000948967,0.000021035694],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004064939,0.0002337832,0.61079603,0.000012858707,0.00013226048,0.000020841753,0.0005369538,5.7659474e-7,0.37347603,0.000047931015,0.000075648284,0.014626424],"study_design_scores_gemma":[0.0024986488,0.00033526885,0.46702334,0.000024471914,0.00006079212,0.0000029301373,0.00017252492,0.0000874766,0.5271765,0.0011729583,0.0011898739,0.0002552023],"about_ca_topic_score_codex":0.00059029716,"about_ca_topic_score_gemma":0.00036077187,"teacher_disagreement_score":0.15370046,"about_ca_system_score_codex":0.00022939137,"about_ca_system_score_gemma":0.000067258945,"threshold_uncertainty_score":0.7647309},"labels":[],"label_agreement":null},{"id":"W2517821145","doi":"10.3760/cma.j.issn.0254-6450.2016.07.004","title":"[Study on polymorphisms of genes with susceptibility to drug induced liver injury in a cohort receiving anti-tuberculosis treatment].","year":2016,"lang":"en","type":"article","venue":"PubMed","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"SLCO1B1; Single-nucleotide polymorphism; Tuberculosis; Medicine; Liver injury; Logistic regression; Internal medicine; Biology; Gene; Genotype; Genetics; Pathology","score_opus":0.11503385469884495,"score_gpt":0.36226855571215133,"score_spread":0.24723470101330638,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2517821145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931634,0.000023741024,0.000005846205,0.0007030071,0.00044610482,0.004301593,0.000050564162,0.00007587394,0.0012298797],"genre_scores_gemma":[0.99597585,0.000078159144,0.000015397007,0.0002641742,0.00010981883,0.0032388861,0.0000022421902,0.000028218079,0.00028722803],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9973877,0.0008533683,0.00041088168,0.0005812651,0.0002118796,0.0005548914],"domain_scores_gemma":[0.9988445,0.00031523494,0.00015032022,0.00037166453,0.00007317349,0.00024512428],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013376779,0.00028745658,0.00044743615,0.00033546722,0.00013381495,0.00001193186,0.0001912075,0.00023044889,0.000092962815],"category_scores_gemma":[0.00011544183,0.00019632712,0.00007961103,0.0005140041,0.00008539842,0.00015951191,0.000061295694,0.00030174886,0.00004725166],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00089452625,0.0015584269,0.7053009,0.000010729734,0.00017000735,0.000022266422,0.0012747854,0.00001273484,0.03266835,0.00001130527,0.000027411921,0.25804853],"study_design_scores_gemma":[0.0014989828,0.00049178925,0.70902604,0.000017884697,0.00007816083,0.000003617612,0.00010537425,0.0000043700784,0.28817022,0.000017646247,0.00039127018,0.00019467653],"about_ca_topic_score_codex":0.0010669773,"about_ca_topic_score_gemma":0.00178495,"teacher_disagreement_score":0.25785387,"about_ca_system_score_codex":0.00043564072,"about_ca_system_score_gemma":0.000058436217,"threshold_uncertainty_score":0.8005988},"labels":[],"label_agreement":null},{"id":"W2524257392","doi":"10.6000/1927-5129.2016.12.57","title":"Sub-Cellular Damage of Hepatocytes Caused by Different Doses of Diclofenac Sodium in Rabbit","year":2016,"lang":"en","type":"article","venue":"Journal of Basic & Applied Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Diclofenac Sodium; Diclofenac; Medicine; Saline; Endoplasmic reticulum; Analgesic; Granulation tissue; Body weight; Rheumatoid arthritis; Pharmacology; Sodium; Internal medicine; Surgery; Chemistry; Wound healing","score_opus":0.07947349803683568,"score_gpt":0.35864701680753264,"score_spread":0.27917351877069696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2524257392","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99685585,0.00032861737,0.00034005466,0.00059193245,0.0005458052,0.00027454013,0.000024135516,0.000008839986,0.001030191],"genre_scores_gemma":[0.99931055,0.00033050554,0.000049773964,0.0001280482,0.00010636841,0.000010732474,6.6580066e-7,0.000008343109,0.000055009394],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978627,0.0003196492,0.000831815,0.00020694784,0.00044291557,0.00033595052],"domain_scores_gemma":[0.998118,0.00064299203,0.0008759214,0.00011897488,0.00010105666,0.00014306833],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0023151732,0.00018041697,0.00050157076,0.0003085015,0.00014281113,0.000012690479,0.0004713525,0.00021034482,0.00022821136],"category_scores_gemma":[0.000092837705,0.000114185015,0.0001260145,0.00038281095,0.0007731314,0.00020371978,0.000062488376,0.00047431915,0.000008001008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022655512,0.00041164138,0.029995123,0.0000475942,0.000041788775,0.000007959042,0.0004479023,0.000026205582,0.95932764,0.0007281774,0.00030809134,0.008431346],"study_design_scores_gemma":[0.0019774593,0.0003020682,0.005055542,0.000082868755,0.00004726026,0.000005797035,0.00024335863,0.00009928277,0.9886195,0.0020621996,0.0013683736,0.0001363005],"about_ca_topic_score_codex":0.000022688047,"about_ca_topic_score_gemma":0.000032395335,"teacher_disagreement_score":0.029291874,"about_ca_system_score_codex":0.000076364784,"about_ca_system_score_gemma":0.00016679626,"threshold_uncertainty_score":0.46563298},"labels":[],"label_agreement":null},{"id":"W2530554915","doi":"10.1007/s40268-016-0145-9","title":"Bioequivalence and Pharmacokinetic Evaluation Study of Acetaminophen vs. Acetaminophen Plus Caffeine Tablets in Healthy Mexican Volunteers","year":2016,"lang":"en","type":"article","venue":"Drugs in R&D","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Fraser Health","funders":"","keywords":"Bioequivalence; Acetaminophen; Medicine; Pharmacokinetics; Caffeine; Pharmacology; Immediate release; Internal medicine","score_opus":0.12560134980769763,"score_gpt":0.43794328977569874,"score_spread":0.3123419399680011,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2530554915","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99434215,0.00049830484,0.000029544542,0.0011088416,0.0008628772,0.0022626412,0.00003468676,0.000043364016,0.0008175841],"genre_scores_gemma":[0.9984056,0.00047811546,0.000045878187,0.00038514368,0.00010375355,0.0003693397,0.000006545032,0.000025709414,0.00017996147],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9961994,0.0015392201,0.00070869655,0.0005745472,0.00041767608,0.0005604352],"domain_scores_gemma":[0.99871814,0.0004702098,0.00024142062,0.00027040238,0.0001227905,0.00017703765],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003154419,0.0002884105,0.00050030544,0.0004667997,0.0001199923,0.000010837238,0.00029097998,0.00029180545,0.00041248277],"category_scores_gemma":[0.00020690131,0.00024812177,0.000042782012,0.00059390155,0.00022770558,0.0002596936,0.00014017524,0.000622413,0.000030896957],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0071958127,0.0039630407,0.3653368,0.00061464467,0.00028021412,0.00005754469,0.039699398,0.0047794404,0.25925145,0.00028912953,0.000395213,0.31813732],"study_design_scores_gemma":[0.09483739,0.0061047156,0.6305457,0.00065388303,0.0008691114,0.000053507978,0.009892108,0.09041473,0.15625097,0.0019136484,0.0062965862,0.0021676898],"about_ca_topic_score_codex":0.0011648034,"about_ca_topic_score_gemma":0.0008557139,"teacher_disagreement_score":0.31596962,"about_ca_system_score_codex":0.0004866483,"about_ca_system_score_gemma":0.00018279803,"threshold_uncertainty_score":0.9999971},"labels":[],"label_agreement":null},{"id":"W2531076386","doi":"10.1016/s0000-0000(10)49529-7","title":"10.1016/s0000-0000(10)49529-7","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Medical prescription; Gynecology; Pharmacology","score_opus":0.05941984790071509,"score_gpt":0.3296040919199827,"score_spread":0.2701842440192676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2531076386","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008966665,0.00008903428,0.0000021722144,0.00096445996,0.000025113715,0.0006633687,0.000076335076,0.00037985438,0.988833],"genre_scores_gemma":[0.003695674,0.0000031194238,0.00006111262,0.00058748067,0.0005864278,0.00013654544,0.000040073955,0.000046841575,0.9948427],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979146,0.00044337305,0.0003590157,0.00044475935,0.00020398026,0.00063425186],"domain_scores_gemma":[0.99892175,0.00018258221,0.000071302085,0.00032436705,0.00007786736,0.0004221326],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0006759728,0.00030469574,0.00032021778,0.00015618632,0.00042486584,0.00004328342,0.00036928963,0.00050622615,0.9990566],"category_scores_gemma":[0.000063123676,0.0003200261,0.00013644475,0.00041056908,0.0000995369,0.00017852489,0.000062975574,0.0008603489,0.9960875],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00066289667,0.00022454768,7.0483276e-7,0.000017048551,0.00007705843,0.000018819625,0.00007577615,0.0004381671,0.0022382727,0.0000038811577,0.25988027,0.7363625],"study_design_scores_gemma":[0.0008357913,0.00026435082,0.000030983414,0.000013774652,0.000076621414,0.000033905606,0.000002219163,0.0010073006,0.011320679,0.00006091782,0.9859646,0.0003888616],"about_ca_topic_score_codex":0.000039999537,"about_ca_topic_score_gemma":0.0000012383929,"teacher_disagreement_score":0.73597366,"about_ca_system_score_codex":0.000112792164,"about_ca_system_score_gemma":0.00007148079,"threshold_uncertainty_score":0.9999252},"labels":[],"label_agreement":null},{"id":"W2536091639","doi":"10.1021/acs.chemrestox.6b00357","title":"How Reactive Metabolites Induce an Immune Response That Sometimes Leads to an Idiosyncratic Drug Reaction","year":2016,"lang":"en","type":"review","venue":"Chemical Research in Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":153,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Drug; Immune system; Chemistry; Reactive intermediate; Pharmacology; Medicine; Immunology; Biochemistry","score_opus":0.4296125184536279,"score_gpt":0.5548860485058739,"score_spread":0.12527353005224595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2536091639","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.31725538,0.6681448,0.0000124492935,0.005000519,0.0019209537,0.005828839,0.00025664445,0.00029175766,0.0012886549],"genre_scores_gemma":[0.13272546,0.8581976,0.00020053082,0.00039123045,0.0013953877,0.0038548291,0.00021370019,0.00023250162,0.0027887223],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9708317,0.022649424,0.0011841003,0.002043987,0.00089203386,0.0023987852],"domain_scores_gemma":[0.9868113,0.009471161,0.00052226527,0.001330693,0.00043927284,0.0014253173],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.016640954,0.0010246467,0.0028737956,0.002558352,0.000539999,0.00020053619,0.0018365406,0.0039425045,0.0003585033],"category_scores_gemma":[0.005995064,0.0008587822,0.0004848392,0.002189543,0.0010251944,0.0010882857,0.0006886465,0.009229134,0.000731043],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018356385,0.0008360076,0.000007128804,0.0011468299,0.00015823965,0.00012838708,0.00047091665,3.1486033e-7,0.47460607,0.00038573658,0.0003028389,0.52012193],"study_design_scores_gemma":[0.00081138744,0.0006184671,0.000026763795,0.0013400706,0.00017041904,0.00013152685,0.0002101762,0.000010877303,0.27174565,0.0013417696,0.7228352,0.00075769547],"about_ca_topic_score_codex":0.00007057597,"about_ca_topic_score_gemma":0.000057583067,"teacher_disagreement_score":0.7225324,"about_ca_system_score_codex":0.0023276873,"about_ca_system_score_gemma":0.0015967195,"threshold_uncertainty_score":0.9993863},"labels":[],"label_agreement":null},{"id":"W2537582285","doi":"10.71781/3458","title":"Caractérisation de l'infiltrat inflammatoire de l'hépatite chronique du chien","year":2004,"lang":"fr","type":"dissertation","venue":"Open MIND","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Gynecology; Humanities; Philosophy","score_opus":0.08321134232375085,"score_gpt":0.41686284142858354,"score_spread":0.3336514991048327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2537582285","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93714666,0.00045083734,0.0005807916,0.0018176045,0.0032232637,0.0031651207,0.00023555402,0.000019207177,0.053360987],"genre_scores_gemma":[0.97506833,0.0015284352,0.002741213,0.00070393534,0.0015419745,0.0006200383,0.0017953953,0.00011770968,0.015882984],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.995242,0.0015621668,0.0009496974,0.00087237195,0.00027797316,0.0010957619],"domain_scores_gemma":[0.99758714,0.00034080935,0.0008799595,0.000390161,0.00025664564,0.00054527615],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0023713794,0.00075934926,0.00072889385,0.00026926716,0.0013724781,0.00039235223,0.0009794815,0.0030648876,0.012395984],"category_scores_gemma":[0.0002819953,0.00091958896,0.00027517183,0.00043092988,0.000223811,0.0008658699,0.00014928593,0.0031763674,0.002222625],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00210305,0.0014596297,0.04035316,0.0009911471,0.0010055087,0.0005134167,0.07197151,0.015531614,0.37041587,0.0014850595,0.0009153938,0.49325466],"study_design_scores_gemma":[0.0026691756,0.0003097626,0.020147737,0.0005957772,0.0006607788,0.00025643362,0.0014248082,0.0049967063,0.70001453,0.0011430687,0.2667179,0.0010633386],"about_ca_topic_score_codex":0.0037171738,"about_ca_topic_score_gemma":0.010288964,"teacher_disagreement_score":0.4921913,"about_ca_system_score_codex":0.0023745997,"about_ca_system_score_gemma":0.0040616845,"threshold_uncertainty_score":0.9999276},"labels":[],"label_agreement":null},{"id":"W2547574466","doi":"10.14740/jmc.v7i11.2598","title":"Chronic Khat ( Catha edulis ) Ingestion as a Possible Triggering Agent in the Development of Autoimmune Hepatitis","year":2016,"lang":"en","type":"article","venue":"Journal of Medical Cases","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Khat; Medicine; Cathinone; Autoimmune hepatitis; Ingestion; Hepatitis; Chronic hepatitis; Liver injury; Immunology; Traditional medicine; Pharmacology; Internal medicine; Virus","score_opus":0.1277065370143524,"score_gpt":0.4259322317762646,"score_spread":0.2982256947619122,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2547574466","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904412,0.0016148716,0.00042566116,0.0060703615,0.0010082568,0.00017605955,0.0000036096878,0.00000889485,0.00025109394],"genre_scores_gemma":[0.9973675,0.0016475236,0.000113718976,0.00035502153,0.00041352888,0.00001767512,0.0000011281518,0.0000075662692,0.00007631608],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976766,0.0005975693,0.0007531103,0.00010026816,0.00063952163,0.00023289454],"domain_scores_gemma":[0.99838454,0.000883734,0.00040646124,0.00008721801,0.000090203874,0.00014787163],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0038379927,0.00011673065,0.0002644782,0.00017838653,0.00015388853,0.000010995779,0.00031654708,0.00029041045,0.0010833347],"category_scores_gemma":[0.0012011004,0.00006651702,0.00009385164,0.00020224642,0.000121011035,0.00014805596,0.000050729563,0.0007820233,0.00002521055],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005272228,0.00060272805,0.00934795,0.00017359211,0.000151105,0.0010843148,0.006419681,0.0000544705,0.02693484,0.00032300496,0.0006057179,0.95377535],"study_design_scores_gemma":[0.01140959,0.002788482,0.120251164,0.0036314966,0.0002844352,0.007512223,0.0014770293,0.00078153313,0.5724353,0.0012081024,0.27758217,0.00063841935],"about_ca_topic_score_codex":0.00014628534,"about_ca_topic_score_gemma":0.00047280517,"teacher_disagreement_score":0.953137,"about_ca_system_score_codex":0.00030940486,"about_ca_system_score_gemma":0.0009325014,"threshold_uncertainty_score":0.9998298},"labels":[],"label_agreement":null},{"id":"W2549803295","doi":"10.1002/hep.28945","title":"Elevated FABP1 serum levels are associated with poorer survival in acetaminophen‐induced acute liver failure","year":2016,"lang":"en","type":"article","venue":"Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Medicine; Internal medicine; Acetaminophen; Odds ratio; Receiver operating characteristic; Gastroenterology; Area under the curve; Endocrinology; Pharmacology","score_opus":0.1371949757846061,"score_gpt":0.37103583265625384,"score_spread":0.23384085687164774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2549803295","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99153644,0.000048750804,0.00014355905,0.00468012,0.0011977226,0.00078862614,0.00032920507,0.0002804122,0.000995174],"genre_scores_gemma":[0.996829,0.000069754504,0.000048058377,0.0016630613,0.00013903534,0.00015450333,0.000023124729,0.00006480662,0.0010086588],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9954431,0.0018593075,0.00055682624,0.0007491934,0.0002559287,0.0011356161],"domain_scores_gemma":[0.9980211,0.0007213876,0.00039711336,0.0003562362,0.00023119923,0.00027294696],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000970558,0.00049442315,0.0007863486,0.00032962722,0.00029422628,0.000020384037,0.00039311658,0.0015382856,0.001986756],"category_scores_gemma":[0.00028439442,0.00036949103,0.00012192428,0.000664748,0.0002831033,0.00030129222,0.00012951321,0.0014002055,0.0005292506],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00083133375,0.00053723896,0.7870521,0.000036523255,0.0007820176,0.0011938871,0.0006439089,0.000008887383,0.19556928,0.0010559645,0.00058748416,0.011701361],"study_design_scores_gemma":[0.013042902,0.00075292477,0.6572909,0.00019867999,0.00044447184,0.0003507497,0.00025205378,0.0015796807,0.30912805,0.0011364265,0.014345376,0.0014778413],"about_ca_topic_score_codex":0.00015841809,"about_ca_topic_score_gemma":0.0053353347,"teacher_disagreement_score":0.12976126,"about_ca_system_score_codex":0.0003928053,"about_ca_system_score_gemma":0.0002219844,"threshold_uncertainty_score":0.9998757},"labels":[],"label_agreement":null},{"id":"W2555250785","doi":"10.1007/s00204-016-1885-6","title":"Inhibition of pannexin1 channels alleviates acetaminophen-induced hepatotoxicity","year":2016,"lang":"en","type":"article","venue":"Archives of Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences; European Research Council; National Institutes of Health; Agentschap voor Innovatie door Wetenschap en Technologie; National Institute of Diabetes and Digestive and Kidney Diseases; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Acetaminophen; Pharmacology; Chemistry; Liver injury; Medicine","score_opus":0.11678364123732875,"score_gpt":0.3825607960807614,"score_spread":0.2657771548434326,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2555250785","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.986212,0.00012035232,0.0014241333,0.001568563,0.0012520291,0.0008182345,0.00012512774,0.00010667027,0.008372856],"genre_scores_gemma":[0.9980086,0.00025674838,0.00040813454,0.00044554807,0.00023954867,0.00013039068,0.000011486357,0.000035571957,0.00046395694],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99660486,0.001164739,0.00086857943,0.000510763,0.00019868594,0.0006523564],"domain_scores_gemma":[0.9971627,0.0014878666,0.00062563125,0.0003832137,0.00010161856,0.00023895096],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007253479,0.0003459063,0.00071189774,0.0004150551,0.00018743267,0.000005665341,0.00037658075,0.0006045914,0.0007085737],"category_scores_gemma":[0.00041765854,0.00027797572,0.00029405655,0.00025234726,0.00073840463,0.00021687004,0.00022823003,0.00056044897,0.00008602624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00074593816,0.0006719721,0.0056763077,0.00013241607,0.00020182315,0.000014291417,0.0012933168,0.000038038947,0.92895144,0.005812421,0.00011000814,0.056351997],"study_design_scores_gemma":[0.0024837262,0.0010416732,0.005610403,0.00010166123,0.00007869759,0.000029655206,0.000102508144,0.0003645354,0.9702325,0.017079182,0.0025630512,0.0003124271],"about_ca_topic_score_codex":0.00004908909,"about_ca_topic_score_gemma":0.0000507653,"teacher_disagreement_score":0.05603957,"about_ca_system_score_codex":0.000053675292,"about_ca_system_score_gemma":0.00012523978,"threshold_uncertainty_score":0.9999672},"labels":[],"label_agreement":null},{"id":"W2555748643","doi":"10.1093/ndt/gfw172.28","title":"SP488MYOCARDIAL STUNNING DURING RENAL REPLACEMENT THERAPY FOR ACUTE KIDNEY INJURY","year":2016,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Renal replacement therapy; Acute kidney injury; Stunning; Kidney; Internal medicine; Ischemia","score_opus":0.05283627413630701,"score_gpt":0.3855191822032476,"score_spread":0.33268290806694056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2555748643","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98023874,0.000029587403,0.013656423,0.002452998,0.0011786014,0.0011395499,0.0005907523,0.00021072105,0.00050264294],"genre_scores_gemma":[0.99121654,0.0023635142,0.00036241842,0.003897021,0.000806466,0.000766426,0.00024642693,0.000036411988,0.0003047605],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976193,0.0006158467,0.00049251894,0.0005483272,0.0001734601,0.00055060297],"domain_scores_gemma":[0.9989365,0.0003079922,0.00021665232,0.00021755332,0.000104332146,0.00021696887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009135151,0.00028638818,0.0003901867,0.00019834335,0.0005615733,0.000019658155,0.0001864982,0.0005934753,0.00047216332],"category_scores_gemma":[0.000042689764,0.00023276854,0.0002644003,0.00021357622,0.00014598135,0.00028137828,0.000014306792,0.00036551786,0.00008500436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016186286,0.00015328187,0.006259117,0.000037155853,0.0014203053,0.000016490794,0.0009597462,0.000052572625,0.93602145,0.00029554174,0.000732182,0.037865885],"study_design_scores_gemma":[0.013536261,0.0007821897,0.0127083,0.0000313201,0.0013296119,0.00005180364,0.00001310109,0.00018160681,0.8911828,0.00093628286,0.07878294,0.00046378688],"about_ca_topic_score_codex":0.000020404932,"about_ca_topic_score_gemma":0.000014110098,"teacher_disagreement_score":0.078050755,"about_ca_system_score_codex":0.000121124765,"about_ca_system_score_gemma":0.00008360965,"threshold_uncertainty_score":0.94920254},"labels":[],"label_agreement":null},{"id":"W2560137500","doi":"10.1139/cjpp-2016-0433","title":"Hepato- and neuro-protective influences of biopropolis on thioacetamide-induced acute hepatic encephalopathy in rats","year":2016,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Thioacetamide; Oxidative stress; Hepatic encephalopathy; Hyperammonemia; Antioxidant; Encephalopathy; Medicine; DNA fragmentation; Apoptosis; Internal medicine; Pharmacology; Endocrinology; Chemistry; Biochemistry; Cirrhosis","score_opus":0.061078087890631474,"score_gpt":0.36489060047086724,"score_spread":0.3038125125802358,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2560137500","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951635,0.00039999452,0.000010146051,0.002036199,0.0016783898,0.00044936873,0.00006677271,0.000009251118,0.00018637115],"genre_scores_gemma":[0.9967071,0.00079958956,0.000024660301,0.0021531938,0.00024256892,0.00003182113,0.0000011505559,0.000017319564,0.000022622313],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99706227,0.0013006617,0.0006406444,0.0003428202,0.000093496914,0.00056013087],"domain_scores_gemma":[0.99780995,0.00084254466,0.0005068992,0.00011169037,0.00018681842,0.00054209493],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009016435,0.0002863371,0.000636529,0.00068295974,0.0002456634,0.0000077100485,0.00026885894,0.00052561867,0.0005225985],"category_scores_gemma":[0.00017226345,0.00021572497,0.00009132005,0.0002976043,0.0008903234,0.00025320932,0.000039357223,0.0011176387,0.000012449112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00075133826,0.00007715867,0.018371304,0.00007121034,0.00022496325,0.00018922461,0.0010311052,0.000027421034,0.96623105,0.00048277067,0.00011086075,0.012431568],"study_design_scores_gemma":[0.002753703,0.0015190832,0.049116075,0.00008519623,0.00018054654,0.0002336539,0.00010240863,0.000108478875,0.9366944,0.007566931,0.0013624851,0.000277045],"about_ca_topic_score_codex":0.0011154625,"about_ca_topic_score_gemma":0.0016216832,"teacher_disagreement_score":0.03074477,"about_ca_system_score_codex":0.00012039204,"about_ca_system_score_gemma":0.0005722585,"threshold_uncertainty_score":0.8797009},"labels":[],"label_agreement":null},{"id":"W2561012436","doi":"10.14206/canad.j.clin.nutr.2017.01.01","title":"Iodine: Biochemistry, Deficiency and Application in Clinical Nutrition","year":2016,"lang":"en","type":"article","venue":"Canadian Journal of Clinical Nutrition","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Iodine; Iodine deficiency; Iodised salt; Thyroid; Chemistry; Basal metabolic rate; Aqueous solution; Solvent; Salt (chemistry); Biochemistry; Endocrinology; Internal medicine; Medicine; Organic chemistry","score_opus":0.1656754943379872,"score_gpt":0.482828146346987,"score_spread":0.3171526520089998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2561012436","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9881932,0.0009483681,0.0010304945,0.0074033607,0.001318344,0.0004442363,0.000053199725,0.00001207081,0.0005967008],"genre_scores_gemma":[0.99468535,0.0029001655,0.0003160964,0.0007223856,0.0012821814,0.00003230837,0.000008197716,0.0000112565795,0.000042070787],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99710286,0.0006477683,0.0015489685,0.00026636463,0.00012082924,0.000313212],"domain_scores_gemma":[0.99737966,0.0009169426,0.000536198,0.00013020953,0.00024017929,0.00079681294],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003589074,0.00013624562,0.0003956115,0.00024328034,0.00014897868,0.00002216727,0.00018230006,0.00076615054,0.000107782085],"category_scores_gemma":[0.0013909045,0.00011549962,0.00018380173,0.00023380952,0.0003998121,0.00021923915,0.00001201076,0.0010429163,0.00003654998],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012673781,0.0018011971,0.21896587,0.00027301194,0.000060870454,0.00014338578,0.000083317376,0.0000045811926,0.022735868,0.0012065382,0.008384167,0.7450738],"study_design_scores_gemma":[0.04298947,0.0024381834,0.16271488,0.0016315461,0.00029471877,0.0008173079,0.0003081189,0.0007983659,0.043835223,0.04713664,0.695978,0.0010575462],"about_ca_topic_score_codex":0.00023271439,"about_ca_topic_score_gemma":0.0023501543,"teacher_disagreement_score":0.7440163,"about_ca_system_score_codex":0.00014476308,"about_ca_system_score_gemma":0.0004808938,"threshold_uncertainty_score":0.59092546},"labels":[],"label_agreement":null},{"id":"W2563313380","doi":"10.1007/s40264-016-0493-y","title":"Antibiotic-Induced Liver Injury in Paediatric Outpatients: A Case-Control Study in Primary Care Databases","year":2016,"lang":"en","type":"article","venue":"Drug Safety","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Medicine; Medical prescription; Odds ratio; Confidence interval; Antibiotics; Database; Population; Logistic regression; Pharmacoepidemiology; Azithromycin; Internal medicine; Environmental health; Pharmacology","score_opus":0.07108173828415906,"score_gpt":0.3718132438122116,"score_spread":0.3007315055280525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2563313380","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934398,0.00029001466,0.000045203138,0.00021002955,0.001280974,0.002413242,0.00084524637,0.00009884691,0.0013766325],"genre_scores_gemma":[0.99858516,0.00019980971,0.00003916173,0.0006929845,0.00023976786,0.000091984824,0.000029982433,0.000034615365,0.00008650902],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9958139,0.002034031,0.0006914246,0.0006206373,0.00022066101,0.0006193286],"domain_scores_gemma":[0.9984203,0.0007444965,0.00019106748,0.00037940723,0.00009144117,0.0001733114],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015752797,0.00033458712,0.00047258768,0.00048704664,0.00022989456,0.000013240036,0.00024744248,0.000281265,0.00025436364],"category_scores_gemma":[0.00019649431,0.00027566793,0.00009439387,0.0006148477,0.0000705758,0.0004377511,0.00016210754,0.0009838194,0.000196307],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019537362,0.0017299012,0.71264875,0.00014880783,0.000075708216,0.0019785436,0.0068072854,0.00004848898,0.006373214,0.000041416897,0.00009852639,0.26809564],"study_design_scores_gemma":[0.026923893,0.00080027373,0.9401396,0.000237894,0.00029935734,0.0001653231,0.0048913574,0.0004838568,0.016764956,0.00004347241,0.007938588,0.0013114599],"about_ca_topic_score_codex":0.0011222896,"about_ca_topic_score_gemma":0.0035010604,"teacher_disagreement_score":0.26678416,"about_ca_system_score_codex":0.0007031927,"about_ca_system_score_gemma":0.00017709959,"threshold_uncertainty_score":0.99996954},"labels":[],"label_agreement":null},{"id":"W2564491480","doi":"","title":"Investigation of the Mechanism of Idiosyncratic Drug-induced Liver Injury","year":2014,"lang":"en","type":"dissertation","venue":"TSpace (University of Toronto)","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Baylor University Medical Center; University of Oregon; University of Pittsburgh; University of California, Los Angeles; University of Texas Southwestern Medical Center; Baylor University; Northwestern University; National Institutes of Health; Yale University; Canadian Institutes of Health Research; University of Washington; University of California, San Francisco; Massachusetts General Hospital","keywords":"Mechanism (biology); Liver injury; Drug; Pharmacology; Medicine; Epistemology; Philosophy","score_opus":0.0633844548536767,"score_gpt":0.33489436223297187,"score_spread":0.27150990737929515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2564491480","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9728588,0.00017858377,0.000054640794,0.00019521613,0.0016094957,0.0007551996,0.00005173189,0.000033589407,0.024262778],"genre_scores_gemma":[0.99402314,0.0003164332,0.0001518266,0.000053932657,0.0000674194,0.0000020507857,0.000058890553,0.000022603563,0.005303711],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99808717,0.00079730246,0.00029189847,0.00029020957,0.00031615284,0.00021729666],"domain_scores_gemma":[0.99788916,0.00015291378,0.0011750984,0.0003707405,0.00030500125,0.000107067026],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006736323,0.00026115382,0.000555476,0.00009453659,0.00027310566,0.0000035893956,0.0005579176,0.0008475571,0.003662441],"category_scores_gemma":[0.00006257276,0.00028095712,0.00029344062,0.00015024639,0.00017093596,0.00023050315,0.000085028696,0.0006887121,0.000017136595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010045554,0.0001609063,0.00059742917,0.0021025261,0.00053901185,0.0000035294509,0.046623986,0.000024600107,0.90287364,0.009753176,0.0008846343,0.035432026],"study_design_scores_gemma":[0.0012126103,0.00032164037,0.0393771,0.00044893927,0.00096538384,0.000002244985,0.009907244,0.0014598335,0.94374657,0.0010710653,0.0010242176,0.00046317113],"about_ca_topic_score_codex":0.032058604,"about_ca_topic_score_gemma":0.043564357,"teacher_disagreement_score":0.040872935,"about_ca_system_score_codex":0.00020529321,"about_ca_system_score_gemma":0.00026717345,"threshold_uncertainty_score":0.99996424},"labels":[],"label_agreement":null},{"id":"W2567784110","doi":"10.1053/j.gastro.2016.12.027","title":"American Gastroenterological Association Institute Technical Review on Initial Testing and Management of Acute Liver Disease","year":2017,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Gastroenterology; Internal medicine; Association (psychology); General surgery; Intensive care medicine; Psychology","score_opus":0.14712185231773556,"score_gpt":0.43617573554889394,"score_spread":0.2890538832311584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2567784110","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924384,0.000100394216,0.00030494318,0.004571839,0.00061147904,0.0007691167,0.00009345969,0.000070649534,0.0010397311],"genre_scores_gemma":[0.9894109,0.0041888794,0.0008459564,0.005198327,0.00012867014,0.00014451615,0.000016863303,0.000012352206,0.000053559717],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99812186,0.00046154068,0.00038505974,0.00038795543,0.00017060447,0.00047297147],"domain_scores_gemma":[0.99860364,0.000101288795,0.0006630014,0.00032989506,0.0000782235,0.0002239397],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000749281,0.00021485698,0.00042704368,0.00007417185,0.00039462134,0.000019960673,0.0003347138,0.00014466747,0.00005196936],"category_scores_gemma":[0.00024170693,0.00020258916,0.00010090407,0.00005541033,0.0005476127,0.00014860161,0.00029375305,0.0006932735,0.00002796974],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003606432,0.000723928,0.9456442,0.0008350579,0.000717981,0.00052416546,0.000027601864,0.000030706302,0.0023392662,0.00052729005,0.0013470775,0.043676298],"study_design_scores_gemma":[0.0018777427,0.0018236475,0.9905763,0.00045755817,0.00084003934,0.00008213243,0.0000038993403,0.0003022545,0.00028825115,0.00016883884,0.0034421466,0.0001371469],"about_ca_topic_score_codex":0.000030291449,"about_ca_topic_score_gemma":0.000046279038,"teacher_disagreement_score":0.044932146,"about_ca_system_score_codex":0.00010696434,"about_ca_system_score_gemma":0.000014086876,"threshold_uncertainty_score":0.82613456},"labels":[],"label_agreement":null},{"id":"W2568497083","doi":"10.1016/j.dmpk.2016.10.291","title":"Influence of sex on hepatotoxic and immune responses in a mouse model of chemical-induced liver carcinogenesis","year":2017,"lang":"en","type":"article","venue":"Drug Metabolism and Pharmacokinetics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Carcinogenesis; Immune system; Chemistry; Biology; Immunology; Genetics; Cancer","score_opus":0.09118598656295833,"score_gpt":0.3730012733737039,"score_spread":0.2818152868107456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2568497083","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971791,0.0012594466,0.000007939488,0.00015526952,0.00016021794,0.00057866744,0.0002616025,0.00002515221,0.0003726181],"genre_scores_gemma":[0.99526805,0.0039714295,0.00014056395,0.00027626776,0.000066969726,0.000053558153,0.000004408118,0.000030710555,0.00018804861],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979529,0.00044062175,0.00060557004,0.00040923376,0.00022392932,0.00036778432],"domain_scores_gemma":[0.99847037,0.00032016548,0.0004511462,0.0004338774,0.00012630649,0.00019813832],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010582102,0.00032174846,0.00062984385,0.0002660031,0.0002169411,0.000024289462,0.00038683455,0.00030904298,0.000020976451],"category_scores_gemma":[0.00021209913,0.0003218631,0.00008732124,0.0001198915,0.00043402638,0.00020932396,0.00023787057,0.0007173069,0.0000030173846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00095655175,0.000280474,0.007357838,0.00023746946,0.00007446336,0.000008125814,0.0022841075,0.0021595792,0.97107834,0.0004789833,0.000007211337,0.015076871],"study_design_scores_gemma":[0.0025704326,0.000042656156,0.012884883,0.00004104593,0.00015100329,0.000006181199,0.0000466057,0.030837895,0.95245457,0.00039360728,0.0002846166,0.0002864776],"about_ca_topic_score_codex":0.00040356477,"about_ca_topic_score_gemma":0.0000099526915,"teacher_disagreement_score":0.028678317,"about_ca_system_score_codex":0.000019626708,"about_ca_system_score_gemma":0.00007278451,"threshold_uncertainty_score":0.99992335},"labels":[],"label_agreement":null},{"id":"W2576801365","doi":"10.1186/s12906-017-1561-2","title":"Profile of bioactive compounds in Nymphaea alba L. leaves growing in Egypt: hepatoprotective, antioxidant and anti-inflammatory activity","year":2017,"lang":"en","type":"article","venue":"BMC Complementary and Alternative Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Antioxidant; Traditional medicine; Chemistry; Alkaline phosphatase; Superoxide dismutase; Glutathione; Petroleum ether; Lipid peroxidation; Oxidative stress; Biochemistry; Medicine; Enzyme; Chromatography","score_opus":0.1644518602268078,"score_gpt":0.43235944013203137,"score_spread":0.26790757990522357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2576801365","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959621,0.00025265294,0.00019016018,0.00069782103,0.00047438295,0.0010590174,0.00007827839,0.000017969554,0.0012676064],"genre_scores_gemma":[0.99897957,0.0003906245,0.00014892046,0.00015802009,0.00019527071,0.000078049234,0.000010579121,0.000014209672,0.000024763749],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99792105,0.0006458784,0.00045446373,0.0004464289,0.0001897802,0.00034239824],"domain_scores_gemma":[0.99879396,0.00039790108,0.000426437,0.00020900762,0.000054601198,0.000118122465],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001422998,0.00026664065,0.00055603037,0.00032161234,0.00042797215,0.000016784814,0.00023489386,0.00011182876,0.00016571168],"category_scores_gemma":[0.00012110817,0.00024644376,0.000040050287,0.00011313989,0.0008653025,0.0005813196,0.00024003284,0.000653876,0.0000018231302],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007566413,0.00023321135,0.73470336,0.00023981582,0.0000973061,0.000054065666,0.002023029,0.000019075202,0.24636197,0.0009011804,0.0000143330935,0.014595991],"study_design_scores_gemma":[0.005757932,0.00035649212,0.7725529,0.00030042982,0.000038420192,0.000020924632,0.0010392598,0.004067644,0.21397361,0.0011225332,0.00053928257,0.00023053437],"about_ca_topic_score_codex":0.004363654,"about_ca_topic_score_gemma":0.0022915772,"teacher_disagreement_score":0.037849545,"about_ca_system_score_codex":0.00010004521,"about_ca_system_score_gemma":0.00004428235,"threshold_uncertainty_score":0.9999988},"labels":[],"label_agreement":null},{"id":"W2586930280","doi":"10.7759/cureus.1016","title":"Ciprofloxacin-induced Hepatotoxicity in a Healthy Young Adult","year":2017,"lang":"en","type":"article","venue":"Cureus","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hamilton Health Sciences; Hamilton Regional Laboratory Medicine Program; Brandon Regional Health Authority","funders":"","keywords":"Ciprofloxacin; Medicine; Internal medicine; Abdominal pain; Urinary system; Intensive care medicine; Antibiotics; Adverse effect","score_opus":0.20505322064790485,"score_gpt":0.4734680743516551,"score_spread":0.2684148537037503,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2586930280","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9584545,0.00015064824,0.000054932018,0.0020467725,0.0039062365,0.0009757565,0.00003519195,0.00015722246,0.03421874],"genre_scores_gemma":[0.99619865,0.000326607,0.00009236078,0.0020986686,0.0005937518,0.00023716454,0.000010658226,0.000036862722,0.00040524395],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99742794,0.0004896757,0.000500356,0.0005694163,0.00022020357,0.0007924166],"domain_scores_gemma":[0.9982755,0.00011481862,0.00035771972,0.00077380834,0.00013952954,0.00033860584],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0011380708,0.0003250301,0.00041217028,0.00012689427,0.0013013509,0.00009862474,0.00072077126,0.0008033875,0.00049154286],"category_scores_gemma":[0.00056132406,0.00034119136,0.00013433685,0.00014220258,0.00016289525,0.00052229123,0.00019406658,0.0017265899,0.00044436686],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002647201,0.0019659123,0.63698983,0.00028075234,0.00023859642,0.00039024232,0.0045308266,0.000052023766,0.2778553,0.011912132,0.0020773828,0.061059777],"study_design_scores_gemma":[0.0153287025,0.0017196432,0.37335023,0.00022250183,0.00018713743,0.00016959402,0.0007577212,0.013938266,0.53280437,0.0110556325,0.047988247,0.0024779222],"about_ca_topic_score_codex":0.0035568553,"about_ca_topic_score_gemma":0.008778963,"teacher_disagreement_score":0.26363963,"about_ca_system_score_codex":0.00034783888,"about_ca_system_score_gemma":0.00016879025,"threshold_uncertainty_score":0.9999988},"labels":[],"label_agreement":null},{"id":"W2587778570","doi":"10.1080/15563650.2017.1290253","title":"Accuracy of the paracetamol-aminotransferase multiplication product to predict hepatotoxicity in modified-release paracetamol overdose","year":2017,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Health and Medical Research Council","keywords":"Medicine; Ingestion; Acetylcysteine; Acetaminophen; Context (archaeology); Drug overdose; Liver injury; Anesthesia; Pharmacology; Poison control; Internal medicine; Emergency medicine; Chemistry; Biochemistry","score_opus":0.25332408515258587,"score_gpt":0.49935417206064997,"score_spread":0.2460300869080641,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2587778570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9832006,0.00010934506,0.0003721262,0.0068634273,0.0037884929,0.0038470752,0.0001464881,0.00008858409,0.0015838669],"genre_scores_gemma":[0.99466527,0.0003073207,0.0001693338,0.0032737674,0.0005686801,0.0006015673,0.000012119243,0.000040488343,0.0003614314],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99352163,0.0026111826,0.0017021255,0.0010479415,0.00030662867,0.00081051455],"domain_scores_gemma":[0.9942692,0.0021940435,0.00096488267,0.0018653165,0.00021734084,0.0004892358],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0039836876,0.0004298294,0.0009274499,0.00016012548,0.00085097505,0.000049075887,0.0016436105,0.0011583472,0.00021316679],"category_scores_gemma":[0.010539452,0.00036186186,0.0004235449,0.00033145622,0.0010584214,0.0003590702,0.00049320736,0.0025744643,0.0001750633],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025022116,0.0045494377,0.7315794,0.00018598663,0.00021526734,0.000053268122,0.0005956375,0.0037570836,0.10854336,0.0026374704,0.0011257927,0.14425509],"study_design_scores_gemma":[0.0048538726,0.00054166024,0.77423674,0.00007597627,0.0001464794,0.000021830549,0.000024733929,0.009875133,0.18698809,0.0015376183,0.021204002,0.0004938888],"about_ca_topic_score_codex":0.0002968653,"about_ca_topic_score_gemma":0.00068757276,"teacher_disagreement_score":0.1437612,"about_ca_system_score_codex":0.00022618627,"about_ca_system_score_gemma":0.0003863278,"threshold_uncertainty_score":0.99988335},"labels":[],"label_agreement":null},{"id":"W2591690158","doi":"10.18053/jctres.03.2017s1.001","title":"Immune mechanisms of idiosyncratic drug-induced liver injury","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical and Translational Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Liver injury; Immune system; Drug; Medicine; Immune tolerance; Immunology; Pharmacology","score_opus":0.5417890662845071,"score_gpt":0.6081907546125054,"score_spread":0.06640168832799831,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2591690158","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898344,0.0003401093,0.00054223253,0.004777757,0.0010561063,0.00027031862,0.00002044588,0.0000050211765,0.0031535635],"genre_scores_gemma":[0.99760723,0.0009415393,0.0005627493,0.00009449806,0.0005117928,0.0000048142106,0.0000012350731,0.000010296764,0.00026585456],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9962972,0.0013848101,0.0012151863,0.00017074942,0.0006699243,0.00026215005],"domain_scores_gemma":[0.99593365,0.0022187831,0.0006329286,0.00019036593,0.0007510179,0.00027323756],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.013589134,0.000113275484,0.0004799932,0.00019492375,0.00067773566,0.000046087956,0.00042097425,0.00037009566,0.00037052954],"category_scores_gemma":[0.0015603494,0.00009217936,0.00026089163,0.00009954437,0.00055439,0.0003521574,0.00006592756,0.0024709848,0.000023676343],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008028701,0.0019562056,0.04985441,0.0004015057,0.0009254772,0.0001749276,0.0010418268,0.00004427333,0.19244063,0.06523523,0.0005849627,0.6793119],"study_design_scores_gemma":[0.008028169,0.0021365902,0.44498155,0.00032081993,0.00023443684,0.00012870524,0.00015878426,0.0043599205,0.24601126,0.2764857,0.016779492,0.0003745716],"about_ca_topic_score_codex":0.000042406227,"about_ca_topic_score_gemma":0.000024101582,"teacher_disagreement_score":0.6789373,"about_ca_system_score_codex":0.000009056319,"about_ca_system_score_gemma":0.00036518712,"threshold_uncertainty_score":0.99983037},"labels":[],"label_agreement":null},{"id":"W2592161084","doi":"10.1007/s00204-016-1929-y","title":"Erratum to: Inhibition of pannexin1 channels alleviates acetaminophen-induced hepatotoxicity","year":2017,"lang":"en","type":"erratum","venue":"Archives of Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Acetaminophen; Pharmacology; Chemistry; Medicine","score_opus":0.12845091266892278,"score_gpt":0.4052392417140495,"score_spread":0.27678832904512674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2592161084","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6676,0.0011308946,0.00042003952,0.003973069,0.08642783,0.005313399,0.0015603094,0.00033107185,0.23324338],"genre_scores_gemma":[0.95217943,0.0010294664,0.00042284423,0.0011429745,0.002354881,0.0004861883,0.00044531233,0.00015732189,0.041781593],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9933506,0.0018781769,0.0016850166,0.0012770074,0.00048656965,0.0013226048],"domain_scores_gemma":[0.9944993,0.0009456886,0.0023421675,0.0013280376,0.0002673313,0.000617428],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0012561043,0.001042418,0.0023226717,0.0011561892,0.00068678474,0.000042665597,0.0015176497,0.003343845,0.00054083025],"category_scores_gemma":[0.0011938412,0.0011130676,0.00079156226,0.0003194066,0.0010659856,0.0002559693,0.00091764715,0.0045883623,0.0001635523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017239463,0.0018184581,0.00054635643,0.0018639441,0.0012487728,0.0001223167,0.004262546,0.00021582817,0.76015365,0.0017186962,0.19741628,0.028909191],"study_design_scores_gemma":[0.0028204778,0.0032259503,0.0027524661,0.0009130896,0.0006134889,0.00007516669,0.00018915658,0.0013254902,0.7134892,0.012307622,0.26075235,0.0015355693],"about_ca_topic_score_codex":0.0002724736,"about_ca_topic_score_gemma":0.00041124673,"teacher_disagreement_score":0.28457943,"about_ca_system_score_codex":0.00013725573,"about_ca_system_score_gemma":0.0007540777,"threshold_uncertainty_score":0.9991319},"labels":[],"label_agreement":null},{"id":"W2592507340","doi":"10.1080/1547691x.2017.1290716","title":"Effects of immunization and checkpoint inhibition on amodiaquine-induced liver injury","year":2017,"lang":"en","type":"article","venue":"Journal of Immunotoxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Amodiaquine; Liver injury; Medicine; Immunization; Pharmacology; Cancer research; Immunology; Malaria; Chloroquine; Antibody","score_opus":0.07736138491179168,"score_gpt":0.40442147575158155,"score_spread":0.3270600908397899,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2592507340","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952316,0.00038314683,0.00012952373,0.0005806972,0.0023077757,0.0005299489,0.000006872625,0.000016331238,0.0008140704],"genre_scores_gemma":[0.9978186,0.0011446327,0.00014739967,0.0004681374,0.00030597195,0.000020588941,0.0000022581569,0.000022910453,0.00006953087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99787235,0.00073189486,0.00074187474,0.00018240185,0.0001850182,0.000286459],"domain_scores_gemma":[0.9971047,0.00048264096,0.0016964778,0.00027816353,0.00030838736,0.00012962664],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014178626,0.00022561544,0.0005222783,0.00033679613,0.00055395334,0.00003896965,0.00030848212,0.00065439363,0.00009329271],"category_scores_gemma":[0.0009532665,0.00020818104,0.00016290869,0.00009178636,0.00030876623,0.00041541626,0.00013627592,0.0013382954,0.000021738348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015764916,0.00054484815,0.00097198144,0.00015210772,0.00018032447,0.00008182518,0.00057159807,0.000023661374,0.9546156,0.0008050508,0.00011155796,0.040364947],"study_design_scores_gemma":[0.0030566854,0.0026172143,0.04890073,0.00014835881,0.00014294469,0.00017953599,0.000041396295,0.00020713097,0.9420622,0.000851134,0.0016145582,0.00017810539],"about_ca_topic_score_codex":0.000033566685,"about_ca_topic_score_gemma":0.00000754468,"teacher_disagreement_score":0.047928747,"about_ca_system_score_codex":0.00012981032,"about_ca_system_score_gemma":0.00011855867,"threshold_uncertainty_score":0.84893763},"labels":[],"label_agreement":null},{"id":"W2595789214","doi":"10.1111/hepr.12893","title":"Serum markers for mitochondrial dysfunction and cell death are possible predictive indicators for drug‐induced liver injury by direct acting antivirals","year":2017,"lang":"en","type":"article","venue":"Hepatology Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Alberta Innovates - Health Solutions","keywords":"Internal medicine; Alanine transaminase; Medicine; Liver injury; Elevated transaminases; Gastroenterology; SOD2; Transaminase; Immunology; Biology; Superoxide dismutase","score_opus":0.19940028207519045,"score_gpt":0.47151739627681893,"score_spread":0.2721171142016285,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2595789214","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9856653,0.00022653819,0.0003056305,0.0015209041,0.0024313403,0.0038439543,0.0008004714,0.000108124485,0.0050977143],"genre_scores_gemma":[0.99440455,0.0003675534,0.00020534325,0.00024070284,0.0005994268,0.0014778078,0.000050659113,0.000059675913,0.0025942523],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9958775,0.0014242298,0.0003931091,0.00087765034,0.00027850384,0.001149032],"domain_scores_gemma":[0.99559605,0.0028719397,0.0004392853,0.00044101232,0.00033257587,0.00031913447],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0032188257,0.0003247011,0.00052649167,0.00047458577,0.0040548183,0.00015183073,0.0004921883,0.001084657,0.00009853194],"category_scores_gemma":[0.0018198243,0.00033230148,0.00015496476,0.00019540281,0.00053228135,0.00047647156,0.00027716855,0.0016985644,0.00002976397],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.021011999,0.0010146571,0.4897215,0.0011495375,0.0007857008,0.0000494524,0.0027356867,0.0000049665337,0.28397107,0.00031371234,0.10768193,0.0915598],"study_design_scores_gemma":[0.0070628747,0.0015555702,0.011694559,0.00008540029,0.000246409,0.000019158471,0.0012734844,0.009461169,0.85843235,0.0013174498,0.10813881,0.00071277906],"about_ca_topic_score_codex":0.00021302207,"about_ca_topic_score_gemma":0.00020006453,"teacher_disagreement_score":0.5744613,"about_ca_system_score_codex":0.00020815831,"about_ca_system_score_gemma":0.00026486142,"threshold_uncertainty_score":0.9999129},"labels":[],"label_agreement":null},{"id":"W2604305561","doi":"","title":"L’acétaminophène chez les enfants","year":2013,"lang":"fr","type":"article","venue":"Canadian Family Physician","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Gynecology; Medicine; Humanities; Philosophy","score_opus":0.09817289860779031,"score_gpt":0.34478910015955355,"score_spread":0.24661620155176323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2604305561","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.46646193,0.009083388,0.000040643507,0.010200427,0.010770765,0.0017184968,0.000636636,0.00013718048,0.5009505],"genre_scores_gemma":[0.829551,0.00068761676,0.00007805622,0.14097692,0.0027743978,0.00026457247,0.00010137291,0.000104011466,0.02546205],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9956591,0.00091366074,0.00053751783,0.00072377635,0.000229348,0.0019365735],"domain_scores_gemma":[0.9969055,0.0002032868,0.00021023669,0.00048003462,0.0002327125,0.001968246],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0005260953,0.00063292065,0.00056111475,0.00039312756,0.001205232,0.00016502224,0.00058329443,0.0014456899,0.0016440122],"category_scores_gemma":[0.000030370293,0.0007898393,0.00027406635,0.00069612364,0.00074257806,0.00062723004,0.000069161055,0.0023751366,0.015657635],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023321962,0.0002843063,0.0011472659,0.0001938309,0.00035502494,0.00011613285,0.000863931,0.00017624797,0.05188288,0.0044663744,0.12536733,0.8151233],"study_design_scores_gemma":[0.00097072654,0.00014831653,0.018096238,0.0001235483,0.00020441652,0.000007249021,0.0010001705,0.0029762732,0.017007116,0.0030918354,0.9554515,0.00092259626],"about_ca_topic_score_codex":0.21174875,"about_ca_topic_score_gemma":0.03689549,"teacher_disagreement_score":0.8300842,"about_ca_system_score_codex":0.0011028528,"about_ca_system_score_gemma":0.001120772,"threshold_uncertainty_score":0.99992645},"labels":[],"label_agreement":null},{"id":"W2604380428","doi":"","title":"Ramipril-associated cholestasis in the setting of recurrent drug-induced liver injury.","year":2017,"lang":"en","type":"article","venue":"PubMed","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Medicine; Ramipril; Cholestasis; Elevated transaminases; Liver injury; Gastroenterology; Jaundice; Acute kidney injury; Internal medicine; Hyperkalemia; Liver biopsy; Acetaminophen; Bilirubin; Discontinuation; Pharmacology; Biopsy; Blood pressure","score_opus":0.18904507461219272,"score_gpt":0.41127050907316975,"score_spread":0.22222543446097703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2604380428","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866468,0.000084017745,0.0000030721683,0.0023709445,0.0014311173,0.0015699504,0.00005432565,0.00004548581,0.007794294],"genre_scores_gemma":[0.9978421,0.00013214265,0.000010022754,0.00056624244,0.00017897443,0.0010948686,0.000009907657,0.000016842308,0.00014894067],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99736506,0.001126246,0.00041416247,0.0002884257,0.00023794669,0.00056816667],"domain_scores_gemma":[0.9984781,0.00034512134,0.0005342907,0.00044559786,0.000087760825,0.000109120934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004251754,0.00019505482,0.00028807405,0.00013263433,0.000643038,0.00006765039,0.000730952,0.00033770775,0.000038948114],"category_scores_gemma":[0.0009769631,0.00016368873,0.00011948348,0.00020429087,0.0001313379,0.00024360899,0.00013884512,0.0012396175,0.000025849984],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002239707,0.00060972176,0.06028355,0.00006217245,0.00010166503,0.000015896328,0.0031376644,0.000013981222,0.0017011955,0.00028234415,0.00096105866,0.93260676],"study_design_scores_gemma":[0.0014873475,0.000040988507,0.93981117,0.000027806682,0.00008573706,0.0000045861793,0.00023240791,0.00049869367,0.043465946,0.00047588855,0.013615286,0.00025411876],"about_ca_topic_score_codex":0.00039141584,"about_ca_topic_score_gemma":0.0008858254,"teacher_disagreement_score":0.93235266,"about_ca_system_score_codex":0.00014058544,"about_ca_system_score_gemma":0.00004314934,"threshold_uncertainty_score":0.6675033},"labels":[],"label_agreement":null},{"id":"W2604719911","doi":"10.1016/j.meegid.2017.04.001","title":"Association of CYP2B6 gene polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in a Chinese population","year":2017,"lang":"en","type":"article","venue":"Infection Genetics and Evolution","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"National Natural Science Foundation of China; Specialized Research Fund for the Doctoral Program of Higher Education of China; National Science Foundation","keywords":"Medicine; Population; Genotype; Genetics; Biology; Gene; Environmental health","score_opus":0.04681503390474885,"score_gpt":0.36960208797297645,"score_spread":0.3227870540682276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2604719911","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972424,0.0002190609,0.00016204848,0.00044594688,0.0010381368,0.0004922531,0.000027401125,0.000041706062,0.00033106818],"genre_scores_gemma":[0.99833894,0.0011929712,0.00006639703,0.00005940479,0.00020302641,0.000041620024,0.000018301007,0.000016555636,0.00006277584],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99845546,0.00033712934,0.00042225784,0.0003293815,0.00017701926,0.00027874744],"domain_scores_gemma":[0.998941,0.00008717274,0.0005231921,0.00021619473,0.000118488766,0.00011395265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010652598,0.00020474869,0.00030010383,0.00026009855,0.00066960393,0.000059220147,0.000079019854,0.0004972824,0.000023721193],"category_scores_gemma":[0.0002313003,0.00021898308,0.000065871274,0.00017224171,0.00007349386,0.00030096725,0.00008891342,0.0004510212,0.0000059596186],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045089568,0.00012312901,0.8396181,0.00003773136,0.000046532805,0.0000010057693,0.00020268465,0.0003068969,0.151692,0.00010060676,0.000013532598,0.007812677],"study_design_scores_gemma":[0.0011401973,0.00006968419,0.9444894,0.0000236349,0.000068470465,0.000012837593,0.000008054759,0.015080019,0.03720229,0.0015357814,0.00016512952,0.00020447595],"about_ca_topic_score_codex":0.0056838514,"about_ca_topic_score_gemma":0.003184468,"teacher_disagreement_score":0.11448971,"about_ca_system_score_codex":0.00027260545,"about_ca_system_score_gemma":0.00003066783,"threshold_uncertainty_score":0.8929871},"labels":[],"label_agreement":null},{"id":"W2606830885","doi":"10.14740/gr804w","title":"Iron Pill Gastritis: An Under Diagnosed Condition With Potentially Serious Outcomes","year":2017,"lang":"en","type":"article","venue":"Gastroenterology Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Pill; Gastritis; Internal medicine; Gastroenterology; Pharmacology; Stomach","score_opus":0.21607420897030247,"score_gpt":0.505314239381542,"score_spread":0.28924003041123947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2606830885","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99149346,0.000020471325,0.0006953639,0.004264775,0.0007952258,0.0010040075,0.00009697204,0.00012944762,0.0015002604],"genre_scores_gemma":[0.99669385,0.000092670714,0.00023682918,0.0015614915,0.00031275421,0.00033996467,0.00008870523,0.000045990942,0.0006277368],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9951079,0.0021215028,0.00033475514,0.00066707813,0.00045259492,0.001316191],"domain_scores_gemma":[0.9980064,0.00021280165,0.00021444632,0.00078069605,0.00033046544,0.00045517183],"candidate_categories":["metaepi_narrow","sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0022544926,0.00029545074,0.00040330907,0.0003026635,0.002455696,0.00019660736,0.0008634552,0.00051586615,0.0007384888],"category_scores_gemma":[0.00017214908,0.00026734313,0.00009439176,0.0000885205,0.0013094711,0.0006102635,0.00026767244,0.0023615533,0.00028606158],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003688989,0.0012786805,0.9579554,0.0000609852,0.0002771176,0.00065124314,0.00034344947,0.00044686106,0.023731085,0.00045873589,0.0010406134,0.010066821],"study_design_scores_gemma":[0.006523662,0.0028713653,0.98135763,0.000029698664,0.00007533356,0.00030522916,0.00030959118,0.00029969198,0.004379044,0.0010250167,0.0025963173,0.00022744044],"about_ca_topic_score_codex":0.0004514114,"about_ca_topic_score_gemma":0.0033988506,"teacher_disagreement_score":0.02340219,"about_ca_system_score_codex":0.00015241405,"about_ca_system_score_gemma":0.000117178184,"threshold_uncertainty_score":0.9999779},"labels":[],"label_agreement":null},{"id":"W2612108856","doi":"10.1371/journal.pone.0173573","title":"The effect of acetaminophen on ubiquitin homeostasis in Saccharomyces cerevisiae","year":2017,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Cancer Center Amsterdam; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Acetaminophen; DNA damage; Biology; Toxicity; Ubiquitin; Saccharomyces cerevisiae; Pharmacology; Biochemistry; Gene; Chemistry; DNA","score_opus":0.18524659355842749,"score_gpt":0.40581404554280387,"score_spread":0.22056745198437638,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2612108856","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9872124,0.00035838314,9.576197e-7,0.0016268814,0.00026822876,0.00086221186,0.000032704575,0.000035577814,0.009602628],"genre_scores_gemma":[0.99828506,0.0007156209,0.000022287179,0.00014810669,0.0001858154,0.0001616132,0.0000039003253,0.000017408818,0.0004602145],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981373,0.0007653506,0.0002958361,0.00023623552,0.00022166294,0.00034363504],"domain_scores_gemma":[0.9980251,0.0010724345,0.0002993845,0.00047635147,0.00004146414,0.00008525039],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001650507,0.00018097283,0.00037097884,0.00008403227,0.000765429,0.00005162247,0.0005326737,0.00027640624,0.00020613037],"category_scores_gemma":[0.00066126167,0.00013385728,0.00008371115,0.00008110541,0.00022759447,0.00012810653,0.00010798597,0.0008560129,0.00018568027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036925513,0.0023245637,0.21716471,0.0011367791,0.0012105687,0.000047795762,0.001237352,0.000050602666,0.42128327,0.0016441685,0.00048901665,0.34971863],"study_design_scores_gemma":[0.0015903285,0.00069774705,0.026067434,0.00018258051,0.00014974126,0.0000011626026,0.000026281352,0.0003018579,0.9680288,0.00029871397,0.0024987448,0.0001566079],"about_ca_topic_score_codex":0.00007491722,"about_ca_topic_score_gemma":0.00008967595,"teacher_disagreement_score":0.54674554,"about_ca_system_score_codex":0.00006319803,"about_ca_system_score_gemma":0.000024321345,"threshold_uncertainty_score":0.5887138},"labels":[],"label_agreement":null},{"id":"W2615780692","doi":"10.1021/acs.chemrestox.7b00065","title":"Supernatant from Hepatocyte Cultures with Drugs That Cause Idiosyncratic Liver Injury Activates Macrophage Inflammasomes","year":2017,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Inflammasome; Hepatocyte; Macrophage; Liver injury; Metabolite; Chemistry; Amodiaquine; Pharmacology; Cell culture; Biology; Inflammation; Biochemistry; Immunology; In vitro; Chloroquine","score_opus":0.29841391163850134,"score_gpt":0.5087503789373568,"score_spread":0.2103364672988554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2615780692","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99107647,0.00043882523,0.000007861655,0.0029000805,0.00064421963,0.0011852753,0.00011087859,0.000102482365,0.003533927],"genre_scores_gemma":[0.9961729,0.0013651003,0.0001707334,0.00054343103,0.00065739296,0.00052690296,0.000043099266,0.000057845045,0.00046257823],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9949426,0.0014846135,0.0004644997,0.000960176,0.0006596253,0.0014884843],"domain_scores_gemma":[0.99623597,0.0018202314,0.00022761652,0.00091085274,0.00021619686,0.000589151],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0021134706,0.00044593294,0.00064547366,0.0003186246,0.0011172777,0.00021943563,0.0014706767,0.0014049325,0.0012023723],"category_scores_gemma":[0.0012099723,0.00037077762,0.000116974414,0.00028708306,0.0019018694,0.00060847413,0.00081469637,0.0048950757,0.00035286814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0031628974,0.0005631489,0.029986879,0.00011770088,0.00026158683,0.0011984342,0.0025158294,0.00000907018,0.9356403,0.00066573074,0.0011979289,0.02468053],"study_design_scores_gemma":[0.0023282855,0.0003043977,0.00672946,0.00010237918,0.000043041287,0.00003734816,0.00041372908,0.00058734836,0.9639698,0.0031154251,0.02192403,0.0004447159],"about_ca_topic_score_codex":0.0010291198,"about_ca_topic_score_gemma":0.0005179863,"teacher_disagreement_score":0.028329575,"about_ca_system_score_codex":0.00060369424,"about_ca_system_score_gemma":0.00032704213,"threshold_uncertainty_score":0.99989146},"labels":[],"label_agreement":null},{"id":"W2619280991","doi":"10.1016/j.etp.2017.05.005","title":"Attenuation of thioacetamide-induced hepatocellular injury by short-term repeated injections associated with down-regulation of metabolic enzymes and relationship with MHC class II-presenting cells","year":2017,"lang":"en","type":"article","venue":"Experimental and Toxicologic Pathology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Japan Society for the Promotion of Science","keywords":"Thioacetamide; Liver injury; Centrilobular necrosis; Alanine transaminase; TLR4; Inflammation; Necrosis; Internal medicine; Endocrinology; Biology; Immunology; Chemistry; Medicine","score_opus":0.10186567413068442,"score_gpt":0.37675339893971727,"score_spread":0.27488772480903284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2619280991","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996992,0.0005752113,0.00009534968,0.00018671057,0.00025100898,0.00081448513,0.000082142724,0.000060142098,0.0009429343],"genre_scores_gemma":[0.9992202,0.00006597716,0.00014203206,0.0000841414,0.000043506756,0.00013632742,0.00007275288,0.000020160776,0.00021491332],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978334,0.0007231274,0.0004808307,0.000467292,0.000173519,0.0003218437],"domain_scores_gemma":[0.9985347,0.00022605018,0.00068547105,0.00029199207,0.00012568817,0.00013613721],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007097557,0.00028386406,0.0005073489,0.0001624559,0.0011771667,0.000026759748,0.00015439907,0.0006038832,0.00005670101],"category_scores_gemma":[0.00017879873,0.00023652769,0.00005627474,0.0001576841,0.00072686933,0.00033291627,0.00013576412,0.0005617675,0.000001643308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032323325,0.00043641418,0.24145432,0.000018913097,0.00011927639,0.000010950046,0.0013221513,0.000014733718,0.75479555,0.0009431105,0.000025079418,0.00053624285],"study_design_scores_gemma":[0.0012643299,0.0013000333,0.15531774,0.00003076596,0.00014203749,0.000044105218,0.00043012336,0.00079752196,0.8401978,0.00015413397,0.00009307858,0.00022834614],"about_ca_topic_score_codex":0.00004672073,"about_ca_topic_score_gemma":0.000025054671,"teacher_disagreement_score":0.08613658,"about_ca_system_score_codex":0.000044174074,"about_ca_system_score_gemma":0.000053221527,"threshold_uncertainty_score":0.96453196},"labels":[],"label_agreement":null},{"id":"W2619831590","doi":"10.3389/fimmu.2017.00626","title":"Ly6Chi Monocytes and Their Macrophage Descendants Regulate Neutrophil Function and Clearance in Acetaminophen-Induced Liver Injury","year":2017,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":105,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Tel Aviv University; Universität Regensburg; Azrieli Foundation; Israel Science Foundation; Weizmann Institute of Science","keywords":"Innate immune system; Monocyte; CD14; Liver injury; Immunology; Biology; Cell biology; Hepatocyte; Immune system; Chemistry; In vitro; Endocrinology; Biochemistry","score_opus":0.06296866832404618,"score_gpt":0.33774926061425614,"score_spread":0.27478059229020996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2619831590","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98999065,0.0045896242,0.00020183992,0.0004467689,0.003706288,0.0005577031,0.000018121636,0.000051764353,0.00043722885],"genre_scores_gemma":[0.99418545,0.0048108553,0.00025645748,0.00029616038,0.00011061058,0.00007020784,0.000004702936,0.000028930714,0.00023662273],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99787694,0.0006348016,0.00035632713,0.00052508316,0.000056493667,0.000550324],"domain_scores_gemma":[0.9991672,0.0000749229,0.0002434218,0.0003928971,0.000033031196,0.00008853597],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006616488,0.0003030143,0.00046958606,0.0003198296,0.0006162009,0.000058028356,0.00030595678,0.00080358225,0.000033724118],"category_scores_gemma":[0.000099109064,0.00030548873,0.000047635745,0.00012253516,0.0005898506,0.0004227534,0.00023411853,0.0014537158,0.000015717345],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005431556,0.00025378933,0.13854101,0.00009328812,0.0002171429,0.00008266326,0.0018760562,0.00002776942,0.29583865,0.00044432233,0.0002606106,0.55693316],"study_design_scores_gemma":[0.004096024,0.00041246257,0.8996994,0.00006737822,0.00004048126,0.00005426889,0.00036577633,0.0046202177,0.07801081,0.00586119,0.006333341,0.00043863908],"about_ca_topic_score_codex":0.0002858315,"about_ca_topic_score_gemma":0.00016373156,"teacher_disagreement_score":0.7611584,"about_ca_system_score_codex":0.00013422486,"about_ca_system_score_gemma":0.000042072013,"threshold_uncertainty_score":0.99993974},"labels":[],"label_agreement":null},{"id":"W2624684789","doi":"10.1002/phar.1972","title":"Bayesian Forecasting Tool to Predict the Need for Antidote in Acute Acetaminophen Overdose","year":2017,"lang":"en","type":"article","venue":"Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"inVentiv Health Clinical","funders":"","keywords":"Nomogram; Medicine; Acetaminophen; Population; acetaminophen overdose; Antidote; Pharmacokinetics; Bayesian probability; Pharmacology; Emergency medicine; Statistics; Internal medicine; Acetylcysteine; Toxicity; Chemistry; Environmental health; Mathematics","score_opus":0.11879006305580657,"score_gpt":0.4359363571360629,"score_spread":0.3171462940802563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2624684789","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9774039,0.0017796285,0.0005301021,0.014377835,0.0030347654,0.0024508336,0.000064091015,0.000037015758,0.00032184497],"genre_scores_gemma":[0.9781678,0.0055895797,0.00012504196,0.013488282,0.0017353076,0.0001820712,0.0000031922027,0.00006784828,0.0006408873],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964255,0.0012149723,0.00095406093,0.0003421034,0.00028256734,0.0007807656],"domain_scores_gemma":[0.99680245,0.0011860979,0.0011301426,0.00037662394,0.00024112516,0.00026358978],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.006580431,0.00047270086,0.00064284494,0.00029444988,0.0031125883,0.00014877805,0.001567635,0.0002645944,0.0005106566],"category_scores_gemma":[0.00007273385,0.00030244753,0.00027238447,0.00018946732,0.00056370057,0.00059087283,0.00014399004,0.0018720351,0.000008207776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011540185,0.0005223763,0.009030603,0.000042497995,0.0013894245,0.00006702928,0.007967689,0.00091353874,0.8680603,0.00015625094,0.018526373,0.08178375],"study_design_scores_gemma":[0.033824325,0.0017630316,0.008980444,0.00009111875,0.00093643024,0.000513386,0.0005643021,0.011025339,0.70484126,0.005907863,0.23063959,0.00091290777],"about_ca_topic_score_codex":0.000051248626,"about_ca_topic_score_gemma":0.0000392715,"teacher_disagreement_score":0.21211322,"about_ca_system_score_codex":0.00011558523,"about_ca_system_score_gemma":0.0001340236,"threshold_uncertainty_score":0.9999428},"labels":[],"label_agreement":null},{"id":"W2625384916","doi":"10.6000/1929-2279.2017.06.02.2","title":"Isoniazid Induced Toxicities and Idiosyncratic Responses in Male Albino Wistar Rats","year":2017,"lang":"en","type":"article","venue":"Journal of cancer research updates","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Isoniazid; Catalase; Alkaline phosphatase; Chemistry; Superoxide dismutase; Pharmacology; Albumin; Micronucleus test; Micronucleus; Internal medicine; Creatinine; Genotoxicity; Antioxidant; Toxicity; Endocrinology; Biochemistry; Medicine; Enzyme; Tuberculosis","score_opus":0.34962084019569806,"score_gpt":0.5647677706683392,"score_spread":0.2151469304726411,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2625384916","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98702127,0.0025786692,0.0000030410372,0.0075722616,0.0007392368,0.0003448441,0.000026121115,0.0000088420575,0.0017057155],"genre_scores_gemma":[0.9932076,0.004640647,0.00006429617,0.00031827032,0.00049768126,0.00004385322,7.743638e-7,0.000019424137,0.0012074562],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99679625,0.0014324624,0.000519112,0.00021715106,0.00047625756,0.00055877684],"domain_scores_gemma":[0.99798924,0.0006864537,0.00040264343,0.00025770947,0.0003983189,0.00026565287],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0054219128,0.0001723101,0.00038609887,0.00052031875,0.0009315329,0.0002344301,0.0005592661,0.00030379876,0.00065621466],"category_scores_gemma":[0.0011495398,0.00015076871,0.00007197518,0.00017050571,0.00050142227,0.000748454,0.00018155402,0.0024147485,0.00002396699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0045442097,0.00025819466,0.104102865,0.00020377987,0.0002313635,0.00053050113,0.002336046,0.00005359938,0.83557254,0.000624051,0.0036095197,0.047933314],"study_design_scores_gemma":[0.0030758397,0.00090984476,0.070132695,0.00038854106,0.000056986406,0.00023788144,0.0010364404,0.00044867155,0.8617742,0.0055157724,0.05608736,0.0003357469],"about_ca_topic_score_codex":0.0005961249,"about_ca_topic_score_gemma":0.0012541853,"teacher_disagreement_score":0.05247784,"about_ca_system_score_codex":0.0002428666,"about_ca_system_score_gemma":0.00054000196,"threshold_uncertainty_score":0.9998867},"labels":[],"label_agreement":null},{"id":"W2726024278","doi":"10.1093/geroni/igx004.1008","title":"AMYLOID BETA PEPTIDES AS ANTIMICROBIAL PEPTIDES: RELEVANCE FOR ALZHEIMER’S DISEASE?","year":2017,"lang":"en","type":"article","venue":"Innovation in Aging","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Antimicrobial peptides; Amyloid (mycology); Herpes simplex virus; Disease; Antimicrobial; Peptide; Amyloid precursor protein; Amyloid beta; Biology; Alzheimer's disease; Immunology; Computational biology; Neuroscience; Medicine; Microbiology; Virus; Biochemistry; Internal medicine; Pathology","score_opus":0.18202175288003097,"score_gpt":0.45623472044154423,"score_spread":0.27421296756151325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2726024278","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.984123,0.000089194786,0.0010885606,0.005885374,0.0021628703,0.0010282682,0.00006384149,0.0001211039,0.0054378146],"genre_scores_gemma":[0.9949594,0.0000711829,0.00068335014,0.0027575765,0.0005979926,0.00021352831,0.00006672516,0.00003142709,0.00061878],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998396,0.00012481668,0.0005465282,0.00039291012,0.0001250133,0.0004147672],"domain_scores_gemma":[0.99862456,0.00023848523,0.0004695622,0.00035086193,0.00023929964,0.00007723885],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012522229,0.00020715458,0.00021943364,0.000303882,0.0011053507,0.00013598938,0.0003791756,0.0002271491,0.00008121729],"category_scores_gemma":[0.00066056236,0.00023771675,0.00006829191,0.00029991928,0.00017933146,0.0005856281,0.000089422756,0.0006657788,0.00012263612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014276495,0.0006151445,0.24924548,0.00045342487,0.00031180022,0.0000679095,0.0027851982,0.0019477588,0.48958826,0.06561059,0.0116145415,0.17633225],"study_design_scores_gemma":[0.0048934217,0.000108509455,0.089777716,0.0003895539,0.00018925857,0.000021089687,0.00020829107,0.0065257316,0.55151486,0.020799238,0.32453325,0.0010390377],"about_ca_topic_score_codex":0.000109289875,"about_ca_topic_score_gemma":0.00005663941,"teacher_disagreement_score":0.31291872,"about_ca_system_score_codex":0.000092997936,"about_ca_system_score_gemma":0.0001327677,"threshold_uncertainty_score":0.9693808},"labels":[],"label_agreement":null},{"id":"W2726860210","doi":"10.4103/sjg.sjg_621_16","title":"The role of N-acetylcysteine in the treatment of non-acetaminophen acute liver failure","year":2017,"lang":"en","type":"editorial","venue":"Saudi Journal of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Medicine; Liver transplantation; Fulminant hepatic failure; Viral hepatitis; Liver disease; Fulminant hepatitis; Hepatitis; Acetaminophen; Jaundice; Population; Autoimmune hepatitis; Internal medicine; Gastroenterology; Transplantation; Pharmacology","score_opus":0.03397238049330723,"score_gpt":0.36944305952196416,"score_spread":0.3354706790286569,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2726860210","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.61313915,0.0032297466,0.000059122052,0.0014433614,0.38013747,0.0011060506,0.0004053718,0.000007733308,0.0004719978],"genre_scores_gemma":[0.80710304,0.019001346,0.00014213838,0.000112998365,0.17312558,0.00008004351,0.000042858916,0.000050800783,0.00034117556],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99582064,0.0017019499,0.0012082888,0.00024389518,0.0004669061,0.0005583102],"domain_scores_gemma":[0.99479026,0.001104937,0.0030397112,0.00050950784,0.0004514848,0.000104108796],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021170476,0.00040875823,0.0011833181,0.00024019092,0.0003056293,0.00002612322,0.0013085161,0.0011331432,0.000053492855],"category_scores_gemma":[0.00019613099,0.00024343582,0.000524448,0.00008755542,0.00063470105,0.00012216509,0.00008635985,0.0022574647,0.000008065635],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.060659938,0.006710919,0.03062809,0.00074555946,0.013251332,0.0013147916,0.017178774,0.00058634725,0.095528886,0.00007160131,0.6867596,0.08656414],"study_design_scores_gemma":[0.005935009,0.0120237535,0.0010183495,0.00012748815,0.0010358653,0.00026459168,0.00037099243,0.00009300566,0.00756264,0.00017992021,0.97125494,0.00013345275],"about_ca_topic_score_codex":0.000091583446,"about_ca_topic_score_gemma":0.0009532694,"teacher_disagreement_score":0.28449532,"about_ca_system_score_codex":0.0001854916,"about_ca_system_score_gemma":0.00027585737,"threshold_uncertainty_score":0.9927025},"labels":[],"label_agreement":null},{"id":"W2735755505","doi":"10.1139/cjpp-2016-0118","title":"Antioxidant compound (<i>E</i>)-2-benzylidene-4-phenyl-1,3-diselenole protects rats against thioacetamide-induced acute hepatotoxicity","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Universidade Federal de Santa Maria","keywords":"Thioacetamide; Lactate dehydrogenase; Chemistry; Glutathione; Alkaline phosphatase; Lipid peroxidation; Ascorbic acid; Pharmacology; Oxidative stress; Glutathione peroxidase; Antioxidant; Intraperitoneal injection; Internal medicine; Endocrinology; Medicine; Superoxide dismutase; Biochemistry; Enzyme","score_opus":0.08611561180495331,"score_gpt":0.3803236277443029,"score_spread":0.2942080159393496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2735755505","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98736334,0.0005748488,0.00003834547,0.0026302892,0.006770441,0.0008978412,0.000118172706,0.000040413383,0.0015663159],"genre_scores_gemma":[0.99316216,0.00071976025,0.00011229446,0.004324649,0.0013821514,0.000057427267,0.000011107334,0.00005075388,0.00017967208],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9957318,0.0013445537,0.0009022016,0.0005799206,0.00015790944,0.0012836496],"domain_scores_gemma":[0.99587476,0.0003101504,0.0013475742,0.00044155645,0.00044655122,0.0015793843],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0016674014,0.0005538656,0.0010231007,0.00046351837,0.0030505164,0.000121040015,0.0011134852,0.0010646636,0.0011922814],"category_scores_gemma":[0.00017304702,0.00053688145,0.00029641853,0.00016769653,0.0011849732,0.0007015444,0.00014873949,0.002968416,0.0000840114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005668748,0.00014822063,0.0038651268,0.00013390247,0.0008974227,0.0008475498,0.0007299064,0.000110606044,0.9853321,0.0003985711,0.0018324044,0.0051373634],"study_design_scores_gemma":[0.0036236187,0.000679892,0.019350698,0.0000614749,0.00044781074,0.0007175089,0.0000889255,0.0007306557,0.9451892,0.0036805612,0.024786618,0.0006430413],"about_ca_topic_score_codex":0.0012742508,"about_ca_topic_score_gemma":0.003103352,"teacher_disagreement_score":0.040142857,"about_ca_system_score_codex":0.0002513259,"about_ca_system_score_gemma":0.0013347749,"threshold_uncertainty_score":0.99972075},"labels":[],"label_agreement":null},{"id":"W2737414819","doi":"10.1177/1756285617722352","title":"Liver injury and glatiramer acetate, an uncommon association: case report and literature review","year":2017,"lang":"en","type":"review","venue":"Therapeutic Advances in Neurological Disorders","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Alberta Innovates - Health Solutions; Biogen; Sanofi","keywords":"Medicine; Glatiramer acetate; Autoimmune hepatitis; Discontinuation; Liver injury; Magnetic resonance imaging; Liver function; Lesion; Multiple sclerosis; Liver biopsy; Past medical history; Hepatitis; Radiology; Gastroenterology; Internal medicine; Surgery; Biopsy; Immunology","score_opus":0.17526836751665378,"score_gpt":0.49953015378177357,"score_spread":0.3242617862651198,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2737414819","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007464889,0.99513626,0.000011889444,0.00043814586,0.0007043032,0.001810786,0.000058368925,0.00008419875,0.0010095602],"genre_scores_gemma":[0.0011677707,0.99526745,0.000046964567,0.0027443357,0.0001389695,0.00032348122,0.00006001261,0.000041498188,0.00020951987],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99511683,0.0025734063,0.0007736964,0.0008715448,0.00017508931,0.00048943434],"domain_scores_gemma":[0.9974746,0.0008710623,0.00094989926,0.00046000993,0.00005173112,0.00019267996],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.001557905,0.0006059234,0.0015575689,0.00013972246,0.00046552432,0.000082939456,0.00030899083,0.0012842682,0.0000876886],"category_scores_gemma":[0.00035387825,0.00047066505,0.00019380805,0.00028018892,0.00033813494,0.0005542052,0.00016584227,0.0031568801,0.000009725314],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006725908,0.00014055712,0.0004851372,0.0077735214,0.00007628931,0.0067113745,0.00008494097,0.0000025762427,2.8191602e-7,0.000115442286,0.000025311278,0.98451734],"study_design_scores_gemma":[0.00035574246,0.00033181798,0.000075991455,0.0024943496,0.00057880103,0.008825881,0.000005654408,0.0000856431,2.5789822e-7,0.0021000367,0.98466784,0.00047799925],"about_ca_topic_score_codex":0.000010082046,"about_ca_topic_score_gemma":0.00011524032,"teacher_disagreement_score":0.9846425,"about_ca_system_score_codex":0.00004980609,"about_ca_system_score_gemma":0.000051476025,"threshold_uncertainty_score":0.9997745},"labels":[],"label_agreement":null},{"id":"W2742710473","doi":"10.1111/1541-4337.12289","title":"The Regulatory Framework Across International Jurisdictions for Risks Associated with Consumption of Botanical Food Supplements","year":2017,"lang":"en","type":"article","venue":"Comprehensive Reviews in Food Science and Food Safety","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"U.S. Food and Drug Administration; European Food Safety Authority; Agri-Food and Veterinary Authority; World Health Organization","keywords":"Business; Legislature; Food safety; China; Novel food; Consumption (sociology); Food products; Public economics; Marketing; Biotechnology; Geography; Food science; Biology; Economics","score_opus":0.35393757712544177,"score_gpt":0.5104361334448485,"score_spread":0.15649855631940673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2742710473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98973083,0.0038581218,0.0010828857,0.0009934647,0.0015688898,0.001980031,0.00043170797,0.000022749917,0.0003313001],"genre_scores_gemma":[0.9915647,0.0076205754,0.00023313267,0.00027061658,0.000081241735,0.00019745376,0.000010835443,0.0000092137925,0.000012218232],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9980002,0.00031881323,0.0005626154,0.0003908073,0.0003093517,0.000418207],"domain_scores_gemma":[0.9975942,0.00075880403,0.0006196803,0.00041992735,0.00048553158,0.00012184927],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0031220764,0.00018121692,0.00036075778,0.00006196959,0.0027557514,0.000096748474,0.0006705127,0.00022689441,0.000015314792],"category_scores_gemma":[0.0012995021,0.00013324818,0.000092563925,0.00019590584,0.0017311478,0.00032370313,0.0002343942,0.0006433986,0.0000034906195],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029746986,0.0016612234,0.2963331,0.00069497677,0.0017411952,0.0000042300107,0.007400991,0.0003014554,0.020287123,0.0718145,0.0010900552,0.59569645],"study_design_scores_gemma":[0.004387666,0.002605294,0.553709,0.00075967517,0.0001417239,0.00002064711,0.00043281395,0.0018687089,0.008795723,0.006453254,0.42030588,0.0005196659],"about_ca_topic_score_codex":0.000004980598,"about_ca_topic_score_gemma":0.0003514956,"teacher_disagreement_score":0.5951768,"about_ca_system_score_codex":0.00015415206,"about_ca_system_score_gemma":0.00012354541,"threshold_uncertainty_score":0.99854255},"labels":[],"label_agreement":null},{"id":"W2743266814","doi":"10.1097/paf.0000000000000339","title":"Toxic Myocarditis Caused by Acetaminophen in a Multidrug Overdose","year":2017,"lang":"en","type":"article","venue":"American Journal of Forensic Medicine & Pathology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Medicine; Myocarditis; Autopsy; Liver transplantation; Acetaminophen; Complication; Anesthesia; Encephalopathy; Transplantation; Surgery; Internal medicine","score_opus":0.07475986203195452,"score_gpt":0.41373768489801843,"score_spread":0.3389778228660639,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2743266814","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9877588,0.00054610864,0.0003128453,0.0059974347,0.0029024284,0.0002826883,0.00002136469,0.000021597563,0.0021567333],"genre_scores_gemma":[0.9936279,0.0007977667,0.00031279464,0.0041353297,0.00083712296,0.000017265862,0.00001007262,0.000030294359,0.0002314532],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99688834,0.001025768,0.00088879233,0.0003192155,0.00029841464,0.0005794989],"domain_scores_gemma":[0.9968161,0.0004647182,0.0016375892,0.00045092404,0.00018808969,0.00044255576],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0020139145,0.00030654005,0.0010661286,0.0003324953,0.00035440648,0.000016416809,0.00059721194,0.00028111128,0.00024785657],"category_scores_gemma":[0.0013732745,0.00025701846,0.00016173955,0.00019147813,0.0022629795,0.00025630323,0.000096906406,0.0017919714,0.000033783093],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001120705,0.0003937564,0.07582902,0.0000464449,0.00032697959,0.0046696,0.008119429,0.00006822208,0.17589068,0.00027882308,0.019588718,0.71366763],"study_design_scores_gemma":[0.060955,0.028908031,0.31762567,0.0013290432,0.0017900977,0.019389562,0.016650137,0.0028736438,0.17869593,0.009241138,0.35942525,0.0031165127],"about_ca_topic_score_codex":0.0002979222,"about_ca_topic_score_gemma":0.000107189604,"teacher_disagreement_score":0.7105511,"about_ca_system_score_codex":0.0001668815,"about_ca_system_score_gemma":0.00016805911,"threshold_uncertainty_score":0.9999882},"labels":[],"label_agreement":null},{"id":"W2746446279","doi":"","title":"Hydroxycutâinduced Liver Toxicity","year":2014,"lang":"en","type":"article","venue":"Annals of Medical and Health Sciences Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Jaundice; Discontinuation; Weight loss; Adverse effect; Liver enzyme; Drug; Public health; Obesity; Environmental health; Physiology; Internal medicine; Pharmacology; Pathology","score_opus":0.7721433370652844,"score_gpt":0.6605159283367833,"score_spread":0.11162740872850108,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2746446279","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86219466,0.0011933843,0.00011710711,0.12378386,0.0003555574,0.00036387666,0.000005697785,0.000030555366,0.011955298],"genre_scores_gemma":[0.9822547,0.0068031433,0.00007279689,0.010321827,0.00032067843,0.000022401036,0.0000014839757,0.0000048307684,0.00019817262],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9950386,0.0018279795,0.00038550605,0.0003656003,0.001570931,0.00081137626],"domain_scores_gemma":[0.9976999,0.0009738544,0.000100586614,0.00012623266,0.00018728297,0.000912137],"candidate_categories":["metaresearch","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.03793109,0.00010370078,0.0002712975,0.0002682155,0.0011198873,0.00002721327,0.00052807166,0.00037839197,0.00094045955],"category_scores_gemma":[0.0010801613,0.000081601866,0.000046626003,0.0006800318,0.0017374323,0.00013347217,0.00021980201,0.0015141965,0.00006976632],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009455582,0.00049364014,0.005814845,0.0005263364,0.000025372732,0.000011391971,0.0013679635,0.000013489288,0.0018775188,0.04084349,0.017250631,0.93168074],"study_design_scores_gemma":[0.0017753752,0.0046774163,0.025149722,0.00041877996,0.000007747932,0.000084041945,0.0006168698,0.087966785,0.08750576,0.031098478,0.76024216,0.00045684134],"about_ca_topic_score_codex":0.0013123221,"about_ca_topic_score_gemma":0.00024681693,"teacher_disagreement_score":0.9312239,"about_ca_system_score_codex":0.000017467328,"about_ca_system_score_gemma":0.00053824624,"threshold_uncertainty_score":0.9999728},"labels":[],"label_agreement":null},{"id":"W2747268192","doi":"10.1139/cjpp-2017-0247","title":"Role of zinc oxide nanoparticles in alleviating hepatic fibrosis and nephrotoxicity induced by thioacetamide in rats","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":85,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Thioacetamide; Malondialdehyde; Chemistry; Lipid peroxidation; Superoxide dismutase; Internal medicine; Endocrinology; Creatinine; Nephrotoxicity; Oxidative stress; Kidney; Fibrosis; Hydroxyproline; Catalase; Pharmacology; Biochemistry; Medicine","score_opus":0.0558757841390638,"score_gpt":0.35604754151229706,"score_spread":0.30017175737323326,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2747268192","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996915,0.0011666176,0.0000011268351,0.0008690646,0.00045355552,0.00036356677,0.000031705753,0.000004530542,0.00019485425],"genre_scores_gemma":[0.99843913,0.00049546076,0.00005770739,0.0008458752,0.00010766023,0.00002515598,0.0000024984251,0.0000142350455,0.000012295878],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973266,0.0011512629,0.00066917343,0.00025576967,0.00006606814,0.0005311146],"domain_scores_gemma":[0.9981956,0.00049880665,0.0006613361,0.00013282173,0.00008619334,0.00042525784],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015153026,0.00022037097,0.0006040101,0.00033238597,0.00042017514,0.000020190128,0.00032747572,0.0004936269,0.00025895122],"category_scores_gemma":[0.00023240718,0.00022410144,0.000063455765,0.00011734709,0.0005735525,0.00032172882,0.00006604925,0.0012449899,0.0000030589158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003701559,0.00008431975,0.07128192,0.000108715954,0.000080658094,0.000033260883,0.0011601541,0.00009067483,0.9235477,0.00011309158,0.000113034504,0.0030163105],"study_design_scores_gemma":[0.0020214135,0.00026046482,0.15325361,0.000049813832,0.000063639476,0.000039698396,0.00017789808,0.00086293207,0.8395836,0.0025790364,0.0009237678,0.000184128],"about_ca_topic_score_codex":0.0053959433,"about_ca_topic_score_gemma":0.014117278,"teacher_disagreement_score":0.08396412,"about_ca_system_score_codex":0.00010040176,"about_ca_system_score_gemma":0.00036469277,"threshold_uncertainty_score":0.9138592},"labels":[],"label_agreement":null},{"id":"W2749707246","doi":"10.1128/aac.00958-17","title":"No Clinically Relevant Drug-Drug Interactions between Methadone or Buprenorphine-Naloxone and Antiviral Combination Glecaprevir and Pibrentasvir","year":2017,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vale (Canada)","funders":"AbbVie","keywords":"Buprenorphine; Drug; Methadone; (+)-Naloxone; Medicine; Pharmacology; Opioid; Internal medicine","score_opus":0.10667240117818193,"score_gpt":0.4269629703697123,"score_spread":0.32029056919153037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2749707246","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98996973,0.000052255473,0.00011512861,0.007019986,0.0008327204,0.0006263047,0.000105554755,0.00006410788,0.0012141984],"genre_scores_gemma":[0.98424596,0.0071499124,0.00047178258,0.0042404844,0.00041491108,0.000017534581,0.000046192352,0.00003522916,0.0033780164],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982624,0.0003013057,0.00048346375,0.00050577766,0.0001065279,0.00034050655],"domain_scores_gemma":[0.9988131,0.0002556995,0.00040214817,0.0002611252,0.00008601319,0.00018194888],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00076705444,0.0003098052,0.0004582772,0.00009526734,0.0012391331,0.00021315253,0.00021959348,0.00021092531,0.00022951857],"category_scores_gemma":[0.000079434154,0.00026941483,0.00007986857,0.000065412176,0.00043405103,0.0005031018,0.00016578959,0.0007586875,0.00003829253],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020375978,0.0011408747,0.45580283,0.00037459043,0.00086909125,0.000032920187,0.002497986,0.0000011306968,0.1467267,0.00017786285,0.02435189,0.36598653],"study_design_scores_gemma":[0.014143448,0.00051779917,0.43284658,0.0003212707,0.0004954723,0.00009577755,0.00010693191,0.001320539,0.10501028,0.0009792,0.4429683,0.0011944117],"about_ca_topic_score_codex":0.00030681398,"about_ca_topic_score_gemma":0.000111397974,"teacher_disagreement_score":0.4186164,"about_ca_system_score_codex":0.000027783632,"about_ca_system_score_gemma":0.000032987875,"threshold_uncertainty_score":0.9999758},"labels":[],"label_agreement":null},{"id":"W2751187983","doi":"10.1016/j.bcp.2017.09.001","title":"Deficiency of N -acetyltransferase increases the interactions of isoniazid with endobiotics in mouse liver","year":2017,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences","keywords":"Acetylation; Isoniazid; Isonicotinic acid; Chemistry; Metabolism; Biochemistry; Pharmacology; Biology; Hydrazide; Gene; Medicine","score_opus":0.10631290904203165,"score_gpt":0.41628447266302954,"score_spread":0.30997156362099787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2751187983","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99599504,0.00046152517,0.000101113976,0.0006596173,0.00047090626,0.000589143,0.000118837146,0.000025538255,0.0015782556],"genre_scores_gemma":[0.9986567,0.0004315719,0.00013458793,0.00043734696,0.00012327441,0.000065472035,0.000008182309,0.000016582799,0.00012629174],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984475,0.00036814436,0.0004334169,0.00027399685,0.00012849331,0.00034848956],"domain_scores_gemma":[0.99859804,0.0005317381,0.00032101216,0.00030756497,0.0001262803,0.0001153414],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049047166,0.00020135914,0.00033760502,0.000117280884,0.00029676282,0.000010785963,0.0005803601,0.00027107517,0.0005486621],"category_scores_gemma":[0.00015627359,0.00015233268,0.00009987833,0.00014258125,0.0010720292,0.00013715812,0.00011925822,0.0009446258,0.000016918992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011014439,0.0011960609,0.00660864,0.00011634045,0.000096525146,0.000019215568,0.00035521525,0.000113687885,0.9866918,0.00039668762,0.0022873916,0.0010170373],"study_design_scores_gemma":[0.002069953,0.00019983968,0.0029411807,0.000022267144,0.00015011203,0.000039210423,0.000090611386,0.00078808004,0.9896705,0.00006299343,0.0038014397,0.00016377532],"about_ca_topic_score_codex":0.00055549975,"about_ca_topic_score_gemma":0.00007392927,"teacher_disagreement_score":0.0036674591,"about_ca_system_score_codex":0.0000649159,"about_ca_system_score_gemma":0.0001215336,"threshold_uncertainty_score":0.6211946},"labels":[],"label_agreement":null},{"id":"W2753475743","doi":"10.1111/bcp.13423","title":"Dose‐dependent acute liver injury with hypersensitivity features in humans due to a novel microsomal prostaglandin E synthase 1 inhibitor","year":2017,"lang":"en","type":"article","venue":"British Journal of Clinical Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Eli Lilly and Company","keywords":"Tolerability; Medicine; Pharmacology; Liver injury; Adverse effect; Dosing; Autoimmune hepatitis; Nimesulide; Pharmacodynamics; Pharmacokinetics; Toxicity; Placebo; Internal medicine; Hepatitis; Pathology","score_opus":0.12607998957790034,"score_gpt":0.47131060029481175,"score_spread":0.3452306107169114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2753475743","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885468,0.00019430132,0.00016183371,0.0024155898,0.006542399,0.0010413318,0.00030261508,0.00003208971,0.0007630268],"genre_scores_gemma":[0.9903452,0.00062439236,0.0006419164,0.0048903716,0.0030248628,0.000047985337,0.0000058581163,0.000044338773,0.00037508763],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9954803,0.001394649,0.0014543952,0.0005711749,0.0003581254,0.0007413842],"domain_scores_gemma":[0.9965032,0.0008210613,0.0013029162,0.00024641218,0.0004034153,0.0007229965],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.004480753,0.00034901037,0.0012071236,0.00026033126,0.0007860332,0.00017048608,0.0006994939,0.00086854177,0.00036566326],"category_scores_gemma":[0.0007931054,0.00035562136,0.00032187862,0.00014735792,0.00064962887,0.0005635374,0.00028295684,0.0046093836,0.0000734062],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.041680403,0.010542107,0.039764233,0.00017422231,0.0019058733,0.061108906,0.00091482495,0.00033813895,0.546383,0.00006210857,0.022357957,0.27476823],"study_design_scores_gemma":[0.04848913,0.005931562,0.6578728,0.0006863445,0.001405368,0.024619645,0.0001840607,0.00030393797,0.2035634,0.0001668235,0.055309854,0.0014670757],"about_ca_topic_score_codex":0.0002982321,"about_ca_topic_score_gemma":0.0012960755,"teacher_disagreement_score":0.6181086,"about_ca_system_score_codex":0.00015702109,"about_ca_system_score_gemma":0.00043547121,"threshold_uncertainty_score":0.99988955},"labels":[],"label_agreement":null},{"id":"W2756587894","doi":"10.1111/1440-1681.12861","title":"Co‐ingestion of aspirin and acetaminophen promoting fulminant liver failure: A critical review of Reye syndrome in the current perspective at the dawn of the 21st century","year":2017,"lang":"en","type":"review","venue":"Clinical and Experimental Pharmacology and Physiology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Aspirin; Acetaminophen; Toxicity; Medicine; Reye Syndrome; Population; Pharmacology; Fulminant hepatic failure; Intensive care medicine; Internal medicine; Environmental health; Liver transplantation","score_opus":0.279288179126119,"score_gpt":0.5462972327672649,"score_spread":0.26700905364114597,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2756587894","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10406813,0.8918527,1.3855862e-7,0.0007891067,0.0010982588,0.0018788858,0.000112983915,0.0000056234485,0.00019417774],"genre_scores_gemma":[0.29282779,0.7064429,0.0000035413714,0.00035770037,0.00014117274,0.00018983147,0.000016221027,0.000011458156,0.000009395011],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9927477,0.005014305,0.0011953466,0.00057428813,0.00013291597,0.0003353961],"domain_scores_gemma":[0.9956909,0.0027680884,0.0010372285,0.00031501756,0.00008815914,0.00010061065],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.002505106,0.00038925052,0.0017217824,0.00006209938,0.00048374044,0.000006978312,0.0005032822,0.0006235088,0.00013107227],"category_scores_gemma":[0.00037221753,0.00020878122,0.00035903446,0.00013240366,0.004720816,0.000076990764,0.00048277678,0.002165768,0.0000042392558],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001076337,0.0029897315,0.00057122065,0.07964884,0.0009787914,0.00003816707,0.0041353023,5.919073e-7,0.008530982,0.0040438613,0.0008473161,0.8971389],"study_design_scores_gemma":[0.003117916,0.002118555,0.003961467,0.021333817,0.003823322,0.0008115745,0.0010171534,0.000062656676,0.00805618,0.0008880995,0.9540577,0.00075154344],"about_ca_topic_score_codex":0.000030600648,"about_ca_topic_score_gemma":0.000009209724,"teacher_disagreement_score":0.9532104,"about_ca_system_score_codex":0.00004847437,"about_ca_system_score_gemma":0.00012345127,"threshold_uncertainty_score":0.99798775},"labels":[],"label_agreement":null},{"id":"W2761464561","doi":"10.1093/alcalc/agx075.62","title":"S16-4DRUG OF USE INTERACTION WITH-ALCOHOL -INDUCED LIVER INJURY","year":2017,"lang":"en","type":"article","venue":"Alcohol and Alcoholism","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Alcohol; Liver injury; Medicine; Pharmacology; Chemistry; Biochemistry","score_opus":0.2726997747676766,"score_gpt":0.4535607476800583,"score_spread":0.18086097291238168,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2761464561","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9899683,0.00012377602,0.00003460646,0.0008692794,0.0013468541,0.00066198607,0.000059318427,0.00009855329,0.006837297],"genre_scores_gemma":[0.99673957,0.00046608795,0.00015580862,0.00084113225,0.00040224535,0.00008333495,0.000013392671,0.000042270458,0.0012561512],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99802583,0.00028982712,0.0004395627,0.0005266151,0.00023796466,0.00048016635],"domain_scores_gemma":[0.9980894,0.0002525837,0.00058354705,0.0006079726,0.0001881248,0.00027838716],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006237427,0.00036784966,0.0004534724,0.00020198607,0.0011330876,0.00017091469,0.00039796333,0.0004950614,0.00030282463],"category_scores_gemma":[0.00019666072,0.00032117544,0.00013002376,0.00011763511,0.00039322802,0.0012472803,0.00021574991,0.0011177456,0.00010382736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027774875,0.0009078276,0.11341697,0.000257057,0.00093527115,0.00018451172,0.0038772176,0.000059261543,0.5607117,0.0033193699,0.0028136282,0.31073976],"study_design_scores_gemma":[0.005857933,0.0007097334,0.20776954,0.00021829244,0.0005845091,0.0002733136,0.0002881638,0.0021028083,0.6498645,0.00070773775,0.13049506,0.0011283968],"about_ca_topic_score_codex":0.0046807807,"about_ca_topic_score_gemma":0.00057636225,"teacher_disagreement_score":0.30961135,"about_ca_system_score_codex":0.000065534805,"about_ca_system_score_gemma":0.00009713018,"threshold_uncertainty_score":0.999924},"labels":[],"label_agreement":null},{"id":"W2761789773","doi":"10.1186/s13613-017-0323-0","title":"The association between FABP7 serum levels with survival and neurological complications in acetaminophen-induced acute liver failure: a nested case–control study","year":2017,"lang":"en","type":"article","venue":"Annals of Intensive Care","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; University of Alberta","keywords":"Medicine; Acetaminophen; Anesthesiology; Nested case-control study; Liver failure; Internal medicine; Case-control study; Anesthesia; Emergency medicine","score_opus":0.26859763603738473,"score_gpt":0.4500210146032725,"score_spread":0.18142337856588775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2761789773","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9825164,0.00008474248,0.000019079345,0.015103773,0.00025043645,0.0013484743,0.00044957327,0.000029064508,0.00019842693],"genre_scores_gemma":[0.99678546,0.000048602822,0.000007904955,0.0028948486,0.00009986807,0.0001056601,0.0000057955995,0.00001485245,0.00003700966],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9977121,0.0010559829,0.00034038658,0.0003404546,0.00018236016,0.00036873273],"domain_scores_gemma":[0.99345464,0.0011708187,0.0004969542,0.00033753586,0.00442402,0.00011601019],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00091102876,0.00021645235,0.00040895483,0.000076747165,0.0011105655,0.00008135655,0.00030393046,0.00034304566,0.000011749721],"category_scores_gemma":[0.002090579,0.00015880437,0.00007290739,0.00011525471,0.00018693326,0.00019155553,0.00012248277,0.00097224786,0.000008082584],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004833016,0.00011282625,0.9701768,0.00002792751,0.0010067546,0.00051326805,0.0058157737,0.000017883916,0.0027363254,0.0001786198,0.0002111001,0.018719414],"study_design_scores_gemma":[0.0020856962,0.0008018201,0.98350024,0.000016889162,0.00030414574,0.00007624604,0.0077821487,0.00023018521,0.004596208,0.00010717987,0.00031345958,0.0001857987],"about_ca_topic_score_codex":0.0002783709,"about_ca_topic_score_gemma":0.0027550734,"teacher_disagreement_score":0.018533615,"about_ca_system_score_codex":0.00004014552,"about_ca_system_score_gemma":0.000054099743,"threshold_uncertainty_score":0.8541685},"labels":[],"label_agreement":null},{"id":"W2762398523","doi":"10.1017/9781139024105.006","title":"Agricultural and Pharmaceutical Benefits","year":2017,"lang":"en","type":"book-chapter","venue":"Cambridge University Press eBooks","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Agriculture; Business; Geography; Archaeology","score_opus":0.14378847012467358,"score_gpt":0.341260144811855,"score_spread":0.19747167468718144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2762398523","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0063718334,0.0006369567,0.000013072824,0.00011460885,0.0011801636,0.0007766996,0.00056564494,0.00019334238,0.99014765],"genre_scores_gemma":[0.030295903,0.0013025162,0.000023146376,0.00026163214,0.00051591266,0.0000032002383,0.000065815126,0.000043153483,0.9674887],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99832875,0.00014401853,0.00022174824,0.0006431414,0.0002039957,0.00045837948],"domain_scores_gemma":[0.998537,0.00014277965,0.00031162723,0.00037298497,0.00015764876,0.00047798143],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00026602167,0.00051743607,0.0004961148,0.00013831565,0.0010616927,0.000076115175,0.0005116157,0.0014266424,0.00004003129],"category_scores_gemma":[0.000022129612,0.0005530046,0.00021196542,0.0000048771194,0.0005916305,0.00017058462,0.00047111363,0.002229805,0.00006882346],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045667094,0.00004276598,0.0000227144,0.00025041937,0.0005714657,0.00030002475,0.00012764664,0.000010892522,0.0016099366,0.92580247,0.0218631,0.048941884],"study_design_scores_gemma":[0.001379296,0.00006698307,0.0002294601,0.00011279927,0.0006216415,0.00011801577,0.000017504775,0.00008919965,0.006442928,0.000021123105,0.99025846,0.0006426189],"about_ca_topic_score_codex":0.000067993744,"about_ca_topic_score_gemma":0.0000072594985,"teacher_disagreement_score":0.96839535,"about_ca_system_score_codex":0.00018293507,"about_ca_system_score_gemma":0.00007804518,"threshold_uncertainty_score":0.9998697},"labels":[],"label_agreement":null},{"id":"W2765609641","doi":"10.12693/aphyspola.132.1030","title":"Interaction Between Grapefruit Juice and Drugs","year":2017,"lang":"en","type":"article","venue":"Acta Physica Polonica A","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Grapefruit juice; Fruit juice; Food science; Chemistry; Pharmacology; Medicine","score_opus":0.14417912273718433,"score_gpt":0.4498613805093615,"score_spread":0.30568225777217717,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765609641","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9535868,0.000039068032,0.0000049856435,0.02326634,0.0010219408,0.00035273904,0.00003133919,0.00011311929,0.021583654],"genre_scores_gemma":[0.99768203,0.00013844196,0.00003655331,0.00066705403,0.0007997584,0.000056848134,0.00001498931,0.000023935469,0.0005803964],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986754,0.00024153061,0.00021646297,0.00036684825,0.00012123063,0.00037853315],"domain_scores_gemma":[0.9986655,0.00031955057,0.0003004702,0.00047274717,0.000047190737,0.00019455673],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.00037811446,0.00021218778,0.00027637195,0.0000683088,0.001318131,0.000119510776,0.00040077048,0.00030199427,0.000104292594],"category_scores_gemma":[0.0001058762,0.00021505711,0.0000973341,0.00006332176,0.00030980844,0.0005787763,0.00021621509,0.0010539794,0.00021370995],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013516237,0.001499473,0.07912095,0.00035345834,0.0019039648,0.000050652452,0.010872517,0.000015873933,0.44655633,0.01306979,0.06705742,0.37814793],"study_design_scores_gemma":[0.0013194038,0.0001703416,0.060181018,0.00003162891,0.00022157824,0.00001404226,0.000120040786,0.00036161373,0.0684976,0.0014469271,0.8672411,0.00039472315],"about_ca_topic_score_codex":0.00026560255,"about_ca_topic_score_gemma":0.000031758205,"teacher_disagreement_score":0.80018365,"about_ca_system_score_codex":0.00004278595,"about_ca_system_score_gemma":0.00004439699,"threshold_uncertainty_score":0.999982},"labels":[],"label_agreement":null},{"id":"W2766678066","doi":"10.1007/s10047-017-1001-6","title":"Acetaminophen clearance during ex vivo continuous renal replacement therapies","year":2017,"lang":"en","type":"article","venue":"Journal of Artificial Organs","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Ex vivo; Medicine; Renal replacement therapy; Acetaminophen; Cardiac surgery; Nephrology; Metabolic clearance rate; Pharmacology; Urology; Internal medicine; Cardiology; Intensive care medicine; In vivo; Pharmacokinetics; Biology","score_opus":0.10895840879327807,"score_gpt":0.4052181654885878,"score_spread":0.29625975669530974,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2766678066","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917217,0.0001571617,0.0002452287,0.0025775973,0.0026843227,0.00024037823,0.000012315763,0.000030887462,0.0023304268],"genre_scores_gemma":[0.99618906,0.00018763206,0.00017506158,0.0003125767,0.0016317442,0.0000043230366,5.055481e-7,0.000024778534,0.0014742964],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982326,0.00029899046,0.00064543163,0.00019067523,0.0002724428,0.00035983117],"domain_scores_gemma":[0.99819136,0.00008661081,0.0010173428,0.00030538967,0.00021713559,0.00018219215],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00131446,0.00019049588,0.00037101065,0.00011631497,0.0011844796,0.00014022549,0.00046852458,0.00027033658,0.0011053579],"category_scores_gemma":[0.00024326009,0.00017119924,0.00017205052,0.00006893425,0.00021330276,0.0004318247,0.00007417766,0.0010652993,0.00012203376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025965695,0.00031042818,0.007816576,0.000032764405,0.0002937431,0.00018513766,0.0025569552,0.00015341176,0.9647148,0.00029756242,0.0008133624,0.020228643],"study_design_scores_gemma":[0.0015613231,0.00042583275,0.022943769,0.000062565836,0.00012858948,0.00019847233,0.00047568887,0.00016287601,0.91843474,0.00090261805,0.05445217,0.0002513613],"about_ca_topic_score_codex":0.000025606912,"about_ca_topic_score_gemma":0.00005835927,"teacher_disagreement_score":0.05363881,"about_ca_system_score_codex":0.00011545508,"about_ca_system_score_gemma":0.000097604585,"threshold_uncertainty_score":0.9998078},"labels":[],"label_agreement":null},{"id":"W2767018077","doi":"10.1371/journal.pone.0186200","title":"Association and clinical utility of NAT2 in the prediction of isoniazid-induced liver injury in Singaporean patients","year":2017,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Biomedical Research Council; Canadian Institutes of Health Research; National University of Singapore; Agency for Science, Technology and Research; Michael Smith Health Research BC","keywords":"Medicine; Single-nucleotide polymorphism; Internal medicine; Isoniazid; Logistic regression; Population; Genotype; Tuberculosis; Case-control study; Pathology; Biology; Genetics; Environmental health","score_opus":0.28887212378795846,"score_gpt":0.4282187091033555,"score_spread":0.13934658531539706,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2767018077","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99738574,0.0000137386305,0.0000011509292,0.0003154531,0.00022110158,0.00060014887,0.000081828206,0.000009436933,0.0013713813],"genre_scores_gemma":[0.999534,0.00019663245,0.000026794543,0.00011532253,0.000069125555,0.000020581769,0.00000909118,0.000005431241,0.000022989436],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9980555,0.0008965891,0.00049619994,0.00017496664,0.00022107598,0.00015566706],"domain_scores_gemma":[0.99871516,0.00040053407,0.0005258267,0.00020445779,0.00011704906,0.000036966714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0027447098,0.00008671308,0.00026117274,0.00008021349,0.00014464058,0.0000104368855,0.00017410112,0.0004344971,0.00003930623],"category_scores_gemma":[0.0013630945,0.000078165736,0.000042967127,0.00008384881,0.00010030876,0.00017444808,0.000058604233,0.00083700847,0.0000035337084],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028690384,0.0035475527,0.97423285,0.000082684826,0.000093621675,9.176423e-7,0.0008978332,2.9609055e-7,0.008485231,0.00002397605,0.000042268708,0.012305856],"study_design_scores_gemma":[0.0013760562,0.00028129597,0.9439128,0.00006702759,0.000101206104,1.2216948e-7,0.00003516982,0.0025981118,0.05121505,0.00028846032,0.00006891097,0.000055764096],"about_ca_topic_score_codex":0.0003557778,"about_ca_topic_score_gemma":0.00037497556,"teacher_disagreement_score":0.042729817,"about_ca_system_score_codex":0.00005839965,"about_ca_system_score_gemma":0.000038496855,"threshold_uncertainty_score":0.3636432},"labels":[],"label_agreement":null},{"id":"W2767216529","doi":"10.1139/cjpp-2017-0423","title":"Glutamine protection in an experimental model of acetaminophen nephrotoxicity","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Acetaminophen; Pharmacology; Nephrotoxicity; Chemistry; Kidney; Glutamine; Antipyretic; In vivo; Myeloperoxidase; Analgesic; Renal function; Biochemistry; Inflammation; Internal medicine; Medicine; Amino acid; Biology","score_opus":0.16184697829483197,"score_gpt":0.41103083138959284,"score_spread":0.24918385309476088,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2767216529","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99680465,0.000260432,0.000058808964,0.0004721771,0.0014986054,0.0004832738,0.00003436628,0.0000067843603,0.00038087912],"genre_scores_gemma":[0.99874794,0.00006622948,0.00011656938,0.0005808693,0.00037302484,0.00003974298,0.0000035290493,0.000016308904,0.000055799075],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980653,0.00062363094,0.0005374692,0.00025111475,0.00007201269,0.00045049426],"domain_scores_gemma":[0.9983839,0.000070671435,0.00067283434,0.00018680497,0.0001593735,0.00052641815],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000867275,0.00021621851,0.00049959304,0.00036419876,0.0005930432,0.00001738018,0.00046215535,0.00055005006,0.0007691626],"category_scores_gemma":[0.00006274577,0.00021782171,0.00009077936,0.000075776865,0.0008437797,0.0005161738,0.000048364855,0.0012180738,0.0000051834204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00063255586,0.0002009853,0.0047703893,0.0000663704,0.00007554603,0.000042558215,0.0011569109,0.002648172,0.9872374,0.00027700182,0.00008764968,0.0028044607],"study_design_scores_gemma":[0.002805365,0.0008032584,0.013214629,0.000018031002,0.0000704642,0.00009031884,0.00011265264,0.016146215,0.96330446,0.0022722993,0.00094982,0.00021250988],"about_ca_topic_score_codex":0.0012301009,"about_ca_topic_score_gemma":0.0030175906,"teacher_disagreement_score":0.023932964,"about_ca_system_score_codex":0.00013786569,"about_ca_system_score_gemma":0.0005559857,"threshold_uncertainty_score":0.8882512},"labels":[],"label_agreement":null},{"id":"W2768171742","doi":"10.1016/j.vascn.2017.09.020","title":"The Effects of Immunization and Checkpoint Inhibition on Amodiaquine-Induced Liver Injury","year":2017,"lang":"en","type":"article","venue":"Journal of Pharmacological and Toxicological Methods","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Amodiaquine; Liver injury; Medicine; Immunization; Pharmacology; Cancer research; Immunology; Malaria; Chloroquine; Antibody","score_opus":0.1698420672283478,"score_gpt":0.5056939901840518,"score_spread":0.335851922955704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2768171742","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929675,0.00088579004,0.001265797,0.0013941447,0.0020759702,0.0006131685,0.000004824759,0.000022673657,0.00077014044],"genre_scores_gemma":[0.99104315,0.004930331,0.0027204298,0.0007675984,0.00043953254,0.000027297463,6.045012e-7,0.000011649739,0.000059400092],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9958613,0.002462909,0.00080794864,0.00026330826,0.00022569958,0.00037883155],"domain_scores_gemma":[0.9932856,0.0047004134,0.0012877983,0.00016932258,0.00023119873,0.0003256469],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0060216817,0.00027243805,0.0005567852,0.000110058485,0.0013248727,0.00008866133,0.0003505048,0.0006243456,0.00008149991],"category_scores_gemma":[0.004104922,0.00015882481,0.00018159628,0.0001098408,0.0007373713,0.00025453852,0.0002773369,0.0017340078,0.0000031272164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015096578,0.0004040297,0.0006192541,0.000056120884,0.0001429131,0.00007254005,0.0001111334,0.000004116926,0.6933058,0.0016484719,0.00007344457,0.30205253],"study_design_scores_gemma":[0.0023089198,0.0046704807,0.05690964,0.00006442139,0.00031021802,0.000108638334,0.00005200039,0.0004660008,0.9233472,0.007305184,0.0042488133,0.00020850713],"about_ca_topic_score_codex":0.0000054802754,"about_ca_topic_score_gemma":0.0000018921468,"teacher_disagreement_score":0.30184403,"about_ca_system_score_codex":0.00007217068,"about_ca_system_score_gemma":0.00004250628,"threshold_uncertainty_score":0.99997526},"labels":[],"label_agreement":null},{"id":"W2768245619","doi":"10.1016/j.fct.2017.10.055","title":"A 90-day subchronic gavage toxicity study in Fischer 344 rats with 3-methylfuran","year":2017,"lang":"en","type":"article","venue":"Food and Chemical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Uric acid; Creatinine; Internal medicine; Endocrinology; Alkaline phosphatase; Toxicity; Kidney; Gamma-glutamyltransferase; Histopathology; Hematology; Blood urea nitrogen; Nephrotoxicity; Atrophy; Biology; Medicine; Pathology; Biochemistry; Enzyme","score_opus":0.11910023450304383,"score_gpt":0.40989969442760005,"score_spread":0.29079945992455625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2768245619","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989793,0.00018840787,0.000024696577,0.0013828077,0.0005493389,0.0011330971,0.00002896018,0.00009047071,0.006809217],"genre_scores_gemma":[0.9980562,0.00006052228,0.000063837644,0.00085111085,0.00032421763,0.00028037358,0.000008707091,0.000035404453,0.00031968212],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971902,0.0007037279,0.00042824485,0.00073079823,0.00017570851,0.00077132403],"domain_scores_gemma":[0.99852294,0.0003499932,0.00024477535,0.00050728495,0.000056571862,0.00031842152],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011454594,0.00038957706,0.00060418126,0.00012763967,0.0006182883,0.00008014507,0.0005082834,0.0008559236,0.00043376553],"category_scores_gemma":[0.0002494509,0.00034209457,0.00008082684,0.0001483005,0.00056650914,0.00024848574,0.0002749748,0.0017338808,0.000051648545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015168951,0.0031331386,0.11298584,0.00010746446,0.00037296064,0.0002611929,0.002484627,0.000020356101,0.85709196,0.000577576,0.00053341035,0.020914575],"study_design_scores_gemma":[0.009355882,0.003943473,0.056747977,0.00004435273,0.00019209753,0.00010036997,0.0005474625,0.00046941327,0.90863425,0.0015368883,0.01753066,0.00089719833],"about_ca_topic_score_codex":0.000058985835,"about_ca_topic_score_gemma":0.0014024593,"teacher_disagreement_score":0.05623786,"about_ca_system_score_codex":0.0001406934,"about_ca_system_score_gemma":0.00011032554,"threshold_uncertainty_score":0.9999031},"labels":[],"label_agreement":null},{"id":"W2775305225","doi":"","title":"Use of the paracetamol-aminotransferase product to predict hepatotoxicity in modified-release paracetamol overdose","year":2016,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Acetaminophen; Medicine; Pharmacology; Drug overdose; Poison control; Anesthesia; Emergency medicine","score_opus":0.32155674422829417,"score_gpt":0.4656962479873554,"score_spread":0.14413950375906126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2775305225","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98408306,0.000071579656,0.0006836519,0.007276712,0.0040591536,0.0030012506,0.00026667133,0.00011816316,0.0004397715],"genre_scores_gemma":[0.9915523,0.00029087797,0.0001639832,0.0060342685,0.0004658475,0.00039584396,0.000005124942,0.00004857127,0.0010431907],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9912831,0.0044056214,0.0018841171,0.0010854596,0.0003389444,0.0010027344],"domain_scores_gemma":[0.99378365,0.0039689443,0.00042680156,0.0010194504,0.00019587645,0.00060528],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0033222833,0.00047625013,0.0010202855,0.00023091503,0.00025343779,0.000020097887,0.00081459986,0.00123595,0.0005269695],"category_scores_gemma":[0.0055536698,0.00031669697,0.00047988986,0.00077976467,0.0010063462,0.00033569848,0.00033811128,0.001893926,0.0002471691],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036216679,0.0045049377,0.6497005,0.00012037402,0.00027989259,0.00011265125,0.00034417893,0.0021437735,0.22014569,0.0035811258,0.0032228848,0.11222229],"study_design_scores_gemma":[0.0071364986,0.0014875524,0.51499903,0.00019466295,0.00024367607,0.000057690188,0.000020218564,0.0023528207,0.3765533,0.0022353232,0.093824305,0.0008949148],"about_ca_topic_score_codex":0.00013016575,"about_ca_topic_score_gemma":0.0004666825,"teacher_disagreement_score":0.15640761,"about_ca_system_score_codex":0.0002982022,"about_ca_system_score_gemma":0.0003865904,"threshold_uncertainty_score":0.99992853},"labels":[],"label_agreement":null},{"id":"W2786394839","doi":"10.1139/cjpp-2017-0651","title":"Hepatoprotective influence of quercetin and ellagic acid on thioacetamide-induced hepatotoxicity in rats","year":2018,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Thioacetamide; Ellagic acid; Pharmacology; Quercetin; Antioxidant; Oxidative stress; Toxicity; Chemistry; Medicine; Biochemistry; Internal medicine","score_opus":0.06327968499590059,"score_gpt":0.3704287859277574,"score_spread":0.3071491009318568,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2786394839","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966253,0.00035088288,0.0000060732386,0.0006992277,0.0011652207,0.00049850997,0.00003136306,0.000010071102,0.0006133568],"genre_scores_gemma":[0.99644405,0.00027520573,0.000039238414,0.0027621961,0.00041575896,0.000022539663,0.0000016872536,0.000018569704,0.000020761043],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968259,0.0014588039,0.0006676042,0.0003612137,0.0000947455,0.0005917764],"domain_scores_gemma":[0.99806,0.00041120593,0.00049993023,0.0001279334,0.0003205034,0.00058046234],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013868044,0.00029808402,0.0006616192,0.0006405473,0.00033294424,0.000008800424,0.0002726198,0.00070961204,0.0006181018],"category_scores_gemma":[0.00017167951,0.00028614543,0.00008416977,0.000355766,0.0011314243,0.00019135306,0.0000465696,0.0018228521,0.000021305746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009460009,0.00009874872,0.014035517,0.00009737159,0.0001396411,0.000089087,0.0017589966,0.00016158965,0.97927725,0.000506388,0.0001349164,0.0027544622],"study_design_scores_gemma":[0.0018733487,0.0016526114,0.05109327,0.00005684705,0.00007747363,0.00016878278,0.000106453524,0.0003390763,0.93911797,0.0036315564,0.0016334057,0.00024918883],"about_ca_topic_score_codex":0.0017284233,"about_ca_topic_score_gemma":0.0042205676,"teacher_disagreement_score":0.040159293,"about_ca_system_score_codex":0.00014325335,"about_ca_system_score_gemma":0.0006189545,"threshold_uncertainty_score":0.99995905},"labels":[],"label_agreement":null},{"id":"W2789607032","doi":"10.1093/jcag/gwy009.022","title":"A22 A HIDDEN CAUSE OF DRUG-INDUCED LIVER FAILURE","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"","keywords":"Medicine; Nimesulide; Liver transplantation; Internal medicine; Jaundice; Liver function; Hepatitis; Chronic liver disease; Acetaminophen; Cirrhosis; Gastroenterology; Transplantation; Surgery; Pharmacology","score_opus":0.05573190618726914,"score_gpt":0.3379176447984096,"score_spread":0.28218573861114044,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2789607032","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9879677,0.000011255082,0.000012950593,0.008774795,0.002271985,0.00020418371,0.000059755213,0.0000048962197,0.0006924359],"genre_scores_gemma":[0.99671584,0.000017655278,0.00011206167,0.002066228,0.00054028403,0.0000031190614,0.0000014900668,0.000012584909,0.0005307545],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99730957,0.0012695014,0.0006490627,0.00011104733,0.0002619112,0.00039893447],"domain_scores_gemma":[0.99683696,0.00018621796,0.0017656729,0.00015519292,0.000803887,0.00025207954],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002025433,0.00013380729,0.00038481186,0.00031355917,0.00022514067,0.000009307099,0.00042967862,0.00038210943,0.00036595526],"category_scores_gemma":[0.0005337324,0.00011322974,0.00022789082,0.00020102922,0.00015665553,0.00012503852,0.00004443243,0.00091516424,0.000018969642],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009593149,0.00022021068,0.91017425,0.000051257146,0.0012192273,0.00002821979,0.0031367207,0.000056738816,0.046064597,0.00040244262,0.03597877,0.0017082415],"study_design_scores_gemma":[0.012203953,0.0047401693,0.65078354,0.00022576193,0.0015909439,0.0007195815,0.00078855676,0.00074223295,0.1825146,0.001830864,0.14338577,0.00047403816],"about_ca_topic_score_codex":0.004456611,"about_ca_topic_score_gemma":0.467618,"teacher_disagreement_score":0.46316138,"about_ca_system_score_codex":0.00089866086,"about_ca_system_score_gemma":0.0005131695,"threshold_uncertainty_score":0.6737092},"labels":[],"label_agreement":null},{"id":"W2791222998","doi":"10.14740/gr911w","title":"Fatal Acute Liver Failure With Intravenous Amiodarone: A Case Report and Literature Review","year":2018,"lang":"en","type":"article","venue":"Gastroenterology Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Amiodarone; Medicine; Liver failure; Complication; Liver damage; Drug; Intravenous drug; Anesthesia; Internal medicine; Pharmacology; Atrial fibrillation","score_opus":0.10967737806545058,"score_gpt":0.45085779187016517,"score_spread":0.3411804138047146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791222998","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906626,0.0026187524,0.00023926672,0.0038454635,0.00029817046,0.0012041713,0.0000866204,0.00008177271,0.0009632269],"genre_scores_gemma":[0.988414,0.006485778,0.0006057286,0.0028600183,0.00057782856,0.00023552713,0.00006431643,0.000032848286,0.0007239914],"study_design_codex":"case_report","study_design_gemma":"case_report","domain_scores_codex":[0.9959339,0.0017929684,0.0003458639,0.00066655345,0.00027985047,0.0009808901],"domain_scores_gemma":[0.99838746,0.00014800687,0.00011725134,0.00041084224,0.0005716378,0.00036478706],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0027375633,0.00026177565,0.0003882708,0.00025732632,0.00082048454,0.000056157696,0.0002401419,0.0004614599,0.0005468157],"category_scores_gemma":[0.00013859749,0.00021390618,0.000058872167,0.0004402483,0.0013641691,0.00021291235,0.00025100404,0.0028707583,0.00017492421],"study_design_candidate":"case_report","study_design_consensus":"case_report","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005956537,0.00081742683,0.0400948,0.0020631365,0.0013939728,0.8599111,0.005660016,0.000001975093,0.01693144,0.0002704597,0.042880096,0.024019055],"study_design_scores_gemma":[0.0021034116,0.0034241378,0.0023263132,0.0006884999,0.00024950557,0.9470258,0.00025204534,0.00022195707,0.004253298,0.000093896204,0.039109092,0.00025204022],"about_ca_topic_score_codex":0.000051919105,"about_ca_topic_score_gemma":0.00076463615,"teacher_disagreement_score":0.08711472,"about_ca_system_score_codex":0.00007957096,"about_ca_system_score_gemma":0.00009296828,"threshold_uncertainty_score":0.99942964},"labels":[],"label_agreement":null},{"id":"W2791498498","doi":"10.1016/j.toxlet.2018.03.024","title":"Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice","year":2018,"lang":"en","type":"article","venue":"Toxicology Letters","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":99,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Chung Shan Medical University; Ministry of Science and Technology, Taiwan; McGill University","keywords":"Pharmacology; Kaempferol; Oxidative stress; Chemistry; CYP2E1; Naringenin; Nitrotyrosine; Antioxidant; Biochemistry; Flavonoid; Medicine; Enzyme; Cytochrome P450; Nitric oxide synthase","score_opus":0.06381051286279832,"score_gpt":0.3590670140622336,"score_spread":0.2952565011994353,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791498498","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99020433,0.000018080022,0.0011494436,0.005732203,0.00031941102,0.0021361255,0.000032007705,0.00007632715,0.00033208277],"genre_scores_gemma":[0.9957438,0.00011825499,0.0007504185,0.002642185,0.00027309402,0.0003742335,0.00004553433,0.000029002926,0.000023472103],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973472,0.0009568608,0.0005762059,0.0005363817,0.00016703439,0.00041632168],"domain_scores_gemma":[0.99863887,0.000301772,0.0005424641,0.00018122143,0.00024089594,0.00009478455],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007436367,0.0003221812,0.00040805517,0.00035842572,0.00036144693,0.000027642289,0.00015285153,0.00065528514,0.000057178175],"category_scores_gemma":[0.00027555216,0.00033897976,0.00004100812,0.0005369111,0.0005541524,0.00091076636,0.00010677215,0.00087832357,0.00001772726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007287307,0.00016395836,0.0056012706,0.000118268996,0.00017270278,0.0000034855516,0.005290029,0.000042348107,0.9722562,0.00044995948,0.00019328584,0.014979802],"study_design_scores_gemma":[0.0016505568,0.0004893291,0.01716412,0.00007959478,0.000070408794,0.0000081440985,0.00024378557,0.00086622563,0.9781431,0.00047710113,0.000496302,0.00031133994],"about_ca_topic_score_codex":0.00016013,"about_ca_topic_score_gemma":0.00015238597,"teacher_disagreement_score":0.014668463,"about_ca_system_score_codex":0.00021727922,"about_ca_system_score_gemma":0.00009126258,"threshold_uncertainty_score":0.99990624},"labels":[],"label_agreement":null},{"id":"W2792000724","doi":"10.1016/j.fct.2018.02.017","title":"Detoxifying effect of pyridoxine on acetaminophen-induced hepatotoxicity via suppressing oxidative stress injury","year":2018,"lang":"en","type":"article","venue":"Food and Chemical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"CYTED Ciencia y Tecnología para el Desarrollo; National Research Foundation of Korea","keywords":"Pyridoxine; Oxidative stress; Pharmacology; Chemistry; Acetaminophen; Glutathione; Lipid peroxidation; Antioxidant; Hepatoprotection; Viability assay; Apoptosis; Biochemistry; Enzyme; Medicine","score_opus":0.07232281706411585,"score_gpt":0.39529543325445243,"score_spread":0.32297261619033657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792000724","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945162,0.000088566565,0.00015277723,0.00024937774,0.0011537641,0.000810499,0.00012217337,0.00014350234,0.002763145],"genre_scores_gemma":[0.998094,0.000032795222,0.00010900963,0.0007314056,0.00078846887,0.00012632468,0.000026678244,0.000044894572,0.00004639872],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966961,0.0009912682,0.00059558713,0.0007201123,0.00023812382,0.0007587948],"domain_scores_gemma":[0.9978385,0.0010038428,0.000338179,0.00032793885,0.00013258761,0.00035893865],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00082832976,0.0004964739,0.0008070467,0.00020697952,0.0004292381,0.000022756807,0.00033885462,0.0012360401,0.000419928],"category_scores_gemma":[0.00036945828,0.00044742355,0.00016698836,0.0003502744,0.0007991346,0.00016602797,0.00024754743,0.0014541926,0.00005879505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020711727,0.0004301668,0.0024428007,0.00017020067,0.00019092737,0.000008812475,0.00059089984,0.0000037497755,0.95478314,0.0002142205,0.00012294027,0.038970955],"study_design_scores_gemma":[0.002118037,0.0064424113,0.00032989265,0.00007177939,0.00013760311,0.00003341048,0.000045558743,0.00084085023,0.98753756,0.0005897489,0.0014137186,0.00043940463],"about_ca_topic_score_codex":0.0000138858795,"about_ca_topic_score_gemma":0.000017131733,"teacher_disagreement_score":0.03853155,"about_ca_system_score_codex":0.000124265,"about_ca_system_score_gemma":0.000055251592,"threshold_uncertainty_score":0.99979776},"labels":[],"label_agreement":null},{"id":"W2793169339","doi":"10.1007/s10620-018-5023-6","title":"Acute Liver Failure from Tumor Necrosis Factor-α Antagonists: Report of Four Cases and Literature Review","year":2018,"lang":"en","type":"review","venue":"Digestive Diseases and Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Medicine; Infliximab; Internal medicine; Hepatology; Tumor necrosis factor alpha; Liver injury; Gastroenterology; Liver transplantation; Liver failure; Necrosis; Liver biopsy; Biopsy; Pathology; Transplantation","score_opus":0.17484452452312577,"score_gpt":0.4537531410727476,"score_spread":0.27890861654962185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2793169339","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.015288995,0.9772933,0.000002319882,0.00012676996,0.0005082738,0.001048095,0.005585087,0.000037848306,0.000109319066],"genre_scores_gemma":[0.0037570372,0.99503374,0.000080418446,0.0003877217,0.00026944213,0.000112525886,0.00022486839,0.000018136789,0.00011611493],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99733484,0.00058806955,0.0006150967,0.00085153576,0.00025944228,0.00035101126],"domain_scores_gemma":[0.9975502,0.00095422775,0.0007532934,0.00022066892,0.00018994062,0.0003316591],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041806913,0.00049536076,0.0013393546,0.00015585659,0.0006505314,0.00013903934,0.00030488972,0.00035712414,0.00017025799],"category_scores_gemma":[0.00050900516,0.0003521651,0.00032738096,0.00055604306,0.0013570492,0.00033401354,0.00018139878,0.00059049967,0.000010351299],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014989208,0.00054330117,0.029421221,0.08484995,0.0018124256,0.012159598,0.0010529282,2.454746e-7,0.000075596945,0.00035033686,0.00799578,0.8615887],"study_design_scores_gemma":[0.00022707354,0.00027165725,0.003228029,0.038931288,0.0036110957,0.0027733843,0.00005929982,0.000015288702,0.000058477144,0.00016545012,0.95000577,0.0006531986],"about_ca_topic_score_codex":0.000087400025,"about_ca_topic_score_gemma":0.000009823071,"teacher_disagreement_score":0.94201,"about_ca_system_score_codex":0.000037995393,"about_ca_system_score_gemma":0.00032539308,"threshold_uncertainty_score":0.999893},"labels":[],"label_agreement":null},{"id":"W2793981729","doi":"10.1007/s13181-018-0657-5","title":"Correction to: Anaphylactoid Reactions to Intravenous N-Acetylcysteine during Treatment for Acetaminophen Poisoning","year":2018,"lang":"en","type":"erratum","venue":"Journal of Medical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Alberta Children's Hospital; Statistics Canada; University of Calgary; Foothills Medical Centre; Centre Hospitalier Universitaire Sainte-Justine; Queen's University; Alberta Health Services","funders":"","keywords":"Medicine; Anaphylactoid reactions; Acetylcysteine; Acetaminophen; Anesthesia; Pharmacology; Anaphylaxis; Chemistry; Organic chemistry; Immunology; Allergy","score_opus":0.10777655161802788,"score_gpt":0.44044193882205734,"score_spread":0.3326653872040295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2793981729","genre_codex":"editorial","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.31751063,0.0016772937,0.012795216,0.033305533,0.6172962,0.0053000734,0.00026318218,0.00025786884,0.01159401],"genre_scores_gemma":[0.37573045,0.007303806,0.005661844,0.018730734,0.14660552,0.0018999864,0.00033627133,0.0006403967,0.44309098],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99488014,0.00094343757,0.0016416535,0.0006092822,0.0008198819,0.0011055791],"domain_scores_gemma":[0.9950514,0.0010601606,0.0012046635,0.00032534357,0.0006231899,0.0017352368],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0030958601,0.0006256721,0.0014430552,0.0010405115,0.00069751864,0.000054674987,0.0007813588,0.00315994,0.0024293035],"category_scores_gemma":[0.003684638,0.00056240533,0.0005720455,0.0005656774,0.00019385557,0.00014117362,0.00016558773,0.004300088,0.00025001634],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035535677,0.0014114394,0.00005517384,0.00034284918,0.0014015941,0.00035947614,0.0023571562,0.00032304024,0.041783433,0.000039586284,0.8501665,0.09820616],"study_design_scores_gemma":[0.0034370718,0.009688757,0.00029593697,0.0005453841,0.0004230615,0.0016237067,0.00020234352,0.0007881758,0.02121897,0.000089118395,0.9612023,0.00048516286],"about_ca_topic_score_codex":0.00010112782,"about_ca_topic_score_gemma":0.0004973016,"teacher_disagreement_score":0.4706907,"about_ca_system_score_codex":0.0021433185,"about_ca_system_score_gemma":0.0016533029,"threshold_uncertainty_score":0.9996827},"labels":[],"label_agreement":null},{"id":"W2800100671","doi":"10.1080/1547691x.2018.1467982","title":"Use of an animal model to test whether non-alcoholic fatty liver disease increases the risk of idiosyncratic drug-induced liver injury","year":2018,"lang":"en","type":"article","venue":"Journal of Immunotoxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Fatty liver; Drug; Liver injury; Alcoholic liver disease; Medicine; Disease; Pharmacology; Internal medicine; Cirrhosis","score_opus":0.12554379305399044,"score_gpt":0.3962747534231165,"score_spread":0.2707309603691261,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2800100671","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99704134,0.00022023875,0.0003282141,0.00038639945,0.00072496163,0.0009868533,0.00019472226,0.000021615811,0.00009562747],"genre_scores_gemma":[0.99641895,0.0004329795,0.00097161805,0.0014721758,0.0005272276,0.00004405141,0.0000031633235,0.00004762025,0.000082207305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9954618,0.002056659,0.001268686,0.00031674627,0.00036377314,0.0005323396],"domain_scores_gemma":[0.9950759,0.0014672984,0.0015573171,0.00054321566,0.00090571475,0.00045055524],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0025241445,0.0003760272,0.0007733966,0.00044558148,0.0004319523,0.00003254292,0.0007872857,0.00047860993,0.00037744094],"category_scores_gemma":[0.0016169067,0.0002846091,0.00036674188,0.00047837253,0.00058103394,0.00061516376,0.00023170437,0.0015417122,0.000055895576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006710855,0.0030508132,0.014949803,0.00008579495,0.00053459476,0.000060265305,0.002804952,0.0017475984,0.96082914,0.00011097187,0.00082469225,0.008290537],"study_design_scores_gemma":[0.0022213645,0.0068996334,0.10946082,0.00014097989,0.0011683363,0.00018391886,0.00020880003,0.06328088,0.8134598,0.0005249841,0.0019520381,0.000498415],"about_ca_topic_score_codex":0.00043980737,"about_ca_topic_score_gemma":0.0002998752,"teacher_disagreement_score":0.1473693,"about_ca_system_score_codex":0.00014895537,"about_ca_system_score_gemma":0.0005461448,"threshold_uncertainty_score":0.9999606},"labels":[],"label_agreement":null},{"id":"W2801150978","doi":"10.1186/s13104-018-3322-9","title":"A case report of nifedipine-induced hepatitis with jaundice","year":2018,"lang":"en","type":"article","venue":"BMC Research Notes","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; University of British Columbia","funders":"","keywords":"Medicine; Nifedipine; Jaundice; Hepatitis; Virology; Internal medicine","score_opus":0.5129684713715055,"score_gpt":0.5515431715429029,"score_spread":0.038574700171397414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2801150978","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9862923,0.000051755487,0.0007721686,0.00040325415,0.0005448141,0.0008732367,0.000031413303,0.00008789524,0.010943137],"genre_scores_gemma":[0.9968905,0.00003561406,0.0012026521,0.00011930194,0.00091267773,0.00015327941,0.000011928501,0.000031834883,0.0006422516],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964696,0.0013582713,0.0004499074,0.00046571757,0.0005655258,0.00069096836],"domain_scores_gemma":[0.9964023,0.0016331983,0.00019195939,0.0004638601,0.0009980197,0.00031062003],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0044029416,0.00019247713,0.0002917177,0.00036469242,0.000734945,0.000033728993,0.000262172,0.00039572382,0.0008808978],"category_scores_gemma":[0.0020375082,0.00016603572,0.0000787799,0.00088593346,0.0007782028,0.00020380762,0.00014521633,0.0013097937,0.00025575922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033358154,0.001797247,0.41832706,0.00095487764,0.0006551404,0.07967131,0.005940961,0.00006960431,0.43272284,0.0031885123,0.004306072,0.049030554],"study_design_scores_gemma":[0.0019017826,0.0021009485,0.0077064843,0.000092462986,0.00007242361,0.03462654,0.00033601682,0.0020768282,0.9311485,0.001156316,0.01838266,0.00039899157],"about_ca_topic_score_codex":0.004954309,"about_ca_topic_score_gemma":0.00529195,"teacher_disagreement_score":0.49842572,"about_ca_system_score_codex":0.00010491193,"about_ca_system_score_gemma":0.0005083094,"threshold_uncertainty_score":0.96452135},"labels":[],"label_agreement":null},{"id":"W2801555155","doi":"10.14740/jem.v8i2-3.498","title":"Liver Dysfunction due to Anti-Thyroid Drugs","year":2018,"lang":"en","type":"article","venue":"Journal of Endocrinology and Metabolism","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Thyroid dysfunction; Thyroid; Liver dysfunction; Internal medicine; Pharmacology","score_opus":0.06591606107031496,"score_gpt":0.37415185181294963,"score_spread":0.3082357907426347,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2801555155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9835472,0.0023469718,0.001134418,0.001816058,0.0065277163,0.00022825005,0.000009092988,0.00003493504,0.004355336],"genre_scores_gemma":[0.99145156,0.0011855969,0.00057230005,0.003563093,0.0025566274,0.000009766421,0.0000010752102,0.000015773958,0.0006442342],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99822456,0.00049547455,0.00046650582,0.00021748927,0.00014155457,0.00045440852],"domain_scores_gemma":[0.9987816,0.00016539732,0.00029416208,0.00012853424,0.00033589266,0.00029437852],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00076464354,0.0001962318,0.00046205477,0.00038667393,0.00036870505,0.000019438496,0.00018998525,0.00030685886,0.0005236336],"category_scores_gemma":[0.0001824646,0.00017058125,0.000114894196,0.0002338954,0.00026752698,0.0002655889,0.00008569896,0.0010610952,0.0002297089],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022503654,0.0006511251,0.0034328583,0.000070644026,0.0008895903,0.00071457773,0.006381283,0.00008283712,0.48058966,0.016781311,0.020027004,0.46812874],"study_design_scores_gemma":[0.0021161584,0.0004948309,0.026722088,0.000014050798,0.00026481276,0.0025861855,0.00018792525,0.00007494556,0.19492535,0.001483135,0.7709186,0.00021190099],"about_ca_topic_score_codex":0.000025611345,"about_ca_topic_score_gemma":0.000012484926,"teacher_disagreement_score":0.7508916,"about_ca_system_score_codex":0.00003170745,"about_ca_system_score_gemma":0.00007210427,"threshold_uncertainty_score":0.6956101},"labels":[],"label_agreement":null},{"id":"W2806572257","doi":"10.1016/j.ijcard.2018.04.007","title":"Dronedarone, amiodarone and other antiarrhythmic drugs, and acute liver injuries: a case-referent study","year":2018,"lang":"en","type":"article","venue":"International Journal of Cardiology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Sanofi","keywords":"Medicine; Dronedarone; Amiodarone; Cardiology; Antiarrhythmic agent; Internal medicine; Atrial fibrillation; Heart disease","score_opus":0.08997662087502313,"score_gpt":0.43765943829399134,"score_spread":0.3476828174189682,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806572257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935054,0.000415381,0.0006798031,0.00055113254,0.002780701,0.00026732733,0.000056464487,0.000017121698,0.001726638],"genre_scores_gemma":[0.9963678,0.0004308673,0.00011933012,0.0007920603,0.0021680046,0.000010828499,0.0000015290161,0.000015280491,0.00009431497],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982916,0.00064856414,0.00044803397,0.00021076958,0.00019140761,0.00020961044],"domain_scores_gemma":[0.998884,0.00019664147,0.00030579933,0.00009062069,0.00038517846,0.00013773973],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010183555,0.000173129,0.00037668916,0.00025524647,0.00017452444,0.000033276625,0.0001735474,0.0002380683,0.00013408226],"category_scores_gemma":[0.00006230415,0.00015055263,0.00008197109,0.000064668304,0.000398144,0.0001728925,0.0001349255,0.00065411255,0.000024015191],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018753624,0.0013489648,0.4331195,0.0000901337,0.02890219,0.026515553,0.042572446,0.0002470444,0.08106565,0.004657193,0.008590769,0.3541369],"study_design_scores_gemma":[0.022301978,0.0132976305,0.09699735,0.00014664994,0.002755685,0.19900516,0.008099011,0.0020368241,0.03581025,0.0057631475,0.612255,0.0015313395],"about_ca_topic_score_codex":0.00006158806,"about_ca_topic_score_gemma":0.00004527942,"teacher_disagreement_score":0.6036642,"about_ca_system_score_codex":0.00007565305,"about_ca_system_score_gemma":0.000061708684,"threshold_uncertainty_score":0.6139358},"labels":[],"label_agreement":null},{"id":"W2807319022","doi":"10.1139/cjpp-2017-0677","title":"1,2-Dichloroethane-induced hepatotoxicity and apoptosis by inhibition of ERK 1/2 pathways","year":2018,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Apoptosis; Toxicity; MAPK/ERK pathway; Kinase; In vitro; p38 mitogen-activated protein kinases; Phosphorylation; Extracellular; Signal transduction; Activator (genetics); Biology; Chemistry; Cell biology; Internal medicine; Medicine; Biochemistry; Receptor","score_opus":0.07603498766869345,"score_gpt":0.35325917821089575,"score_spread":0.2772241905422023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2807319022","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950841,0.000561073,0.000040371648,0.000762274,0.0024922497,0.0003120744,0.00014197326,0.000014478017,0.0005913989],"genre_scores_gemma":[0.99620974,0.00042261236,0.000052119183,0.0024691517,0.0007625534,0.000015660984,0.000012474799,0.000021218182,0.000034473233],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974802,0.00091738824,0.00064084143,0.00030891554,0.000092010014,0.0005606389],"domain_scores_gemma":[0.9978383,0.00033773223,0.00055745075,0.000105110645,0.00035705668,0.0008043466],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00102126,0.0002766064,0.0005871117,0.00036398042,0.0004960055,0.000010271441,0.00018710329,0.0007287997,0.0017485182],"category_scores_gemma":[0.00008791464,0.0002730966,0.00010213267,0.00025537342,0.0012200975,0.00022361893,0.000045070738,0.0011762938,0.000015788295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041064687,0.000092176495,0.0022344,0.00009409961,0.00022912724,0.000018672124,0.0011440802,0.0000037036327,0.9871638,0.00046953355,0.004268721,0.0038710313],"study_design_scores_gemma":[0.0019800167,0.0012442833,0.0016496084,0.000025565032,0.00019391981,0.00017314646,0.000116202355,0.00018936982,0.98086756,0.0029193598,0.010400948,0.00023999615],"about_ca_topic_score_codex":0.0008160971,"about_ca_topic_score_gemma":0.0008452477,"teacher_disagreement_score":0.006296224,"about_ca_system_score_codex":0.00008700479,"about_ca_system_score_gemma":0.0004921232,"threshold_uncertainty_score":0.9999721},"labels":[],"label_agreement":null},{"id":"W2808746332","doi":"10.1021/acs.chemrestox.8b00091","title":"The Effects of Immune Modulators on Amodiaquine-Induced Liver Injury","year":2018,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Amodiaquine; Immune system; Liver injury; Pharmacology; Medicine; Computational biology; Chemistry; Biology; Immunology; Malaria; Chloroquine","score_opus":0.21502651673312564,"score_gpt":0.5115140209732986,"score_spread":0.2964875042401729,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2808746332","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900213,0.00024480055,0.0000044545236,0.0012007437,0.0017040555,0.0011211147,0.000006649376,0.000046894333,0.0056500006],"genre_scores_gemma":[0.9980604,0.00032766184,0.000027440916,0.0004012732,0.0005588197,0.0003455434,0.0000035566252,0.000029141926,0.00024615656],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99528277,0.0021111653,0.00056549924,0.00049173884,0.0004331098,0.0011157077],"domain_scores_gemma":[0.9927107,0.006120621,0.00013437246,0.00048044763,0.00028749212,0.0002663646],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0038925696,0.00023159367,0.000381674,0.00035028165,0.0004681947,0.000019031588,0.0007506598,0.001021718,0.00018848732],"category_scores_gemma":[0.0035689613,0.00018339271,0.00012666546,0.00090395485,0.0016977952,0.00008099885,0.00034821243,0.0031435185,0.00035863285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014054166,0.0005504732,0.0003820958,0.00011180601,0.000053557058,0.000035701054,0.00034356554,0.0000020932605,0.9234021,0.0049478495,0.0009323311,0.06783306],"study_design_scores_gemma":[0.0011436321,0.0017479102,0.0015829571,0.0000597943,0.000010292364,0.000007420851,0.00004057521,0.0008863913,0.97708046,0.0044408673,0.012831973,0.00016774799],"about_ca_topic_score_codex":0.00008377929,"about_ca_topic_score_gemma":0.000038547845,"teacher_disagreement_score":0.06766531,"about_ca_system_score_codex":0.00036507472,"about_ca_system_score_gemma":0.00020273686,"threshold_uncertainty_score":0.9991563},"labels":[],"label_agreement":null},{"id":"W2809005281","doi":"10.1002/rcm.8206","title":"Absolute quantitation of acetaminophen‐modified human serum albumin in acute liver failure patients by liquid chromatography/tandem mass spectrometry","year":2018,"lang":"en","type":"article","venue":"Rapid Communications in Mass Spectrometry","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta Hospital; University of Alberta; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Chromatography; Acetaminophen; Selected reaction monitoring; Liquid chromatography–mass spectrometry; Metabolite; Human serum albumin; Albumin; Serum albumin; Mass spectrometry; Tandem mass spectrometry; In vivo; Blood proteins; Biochemistry","score_opus":0.07811336730196716,"score_gpt":0.386704687263747,"score_spread":0.30859131996177985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2809005281","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882333,0.0010562595,0.0014149066,0.0007100389,0.00047982452,0.0013096743,0.00018159658,0.00012707993,0.006487301],"genre_scores_gemma":[0.98817194,0.0021078587,0.008759386,0.00021136702,0.000112205285,0.00021863963,0.00024408194,0.000054277214,0.00012025748],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9957904,0.0014356248,0.0010952719,0.0005644429,0.00037058894,0.00074367004],"domain_scores_gemma":[0.9971656,0.00046092086,0.0005909997,0.0013967626,0.00022512415,0.00016058481],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015236146,0.0004211471,0.00063846004,0.0017998983,0.0005259268,0.00004263277,0.0015084223,0.00074562756,0.0007036711],"category_scores_gemma":[0.000114601244,0.000494889,0.00020243617,0.003301124,0.00071378413,0.00045032316,0.00028327704,0.00189169,0.00009070742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037563112,0.0021999937,0.08799111,0.00012757226,0.0004845822,0.000007261785,0.0016111105,0.000026543905,0.8970961,0.007494193,0.0011511816,0.0014347131],"study_design_scores_gemma":[0.010160078,0.0034859309,0.30779418,0.00030829484,0.00041467638,0.000018527768,0.0011334576,0.00666159,0.6510086,0.0064712833,0.010790454,0.0017529204],"about_ca_topic_score_codex":0.00015937512,"about_ca_topic_score_gemma":0.0007225624,"teacher_disagreement_score":0.24608749,"about_ca_system_score_codex":0.00047207339,"about_ca_system_score_gemma":0.00008031636,"threshold_uncertainty_score":0.99975026},"labels":[],"label_agreement":null},{"id":"W2809242708","doi":"10.1007/s11901-018-0407-9","title":"Drug-Induced Liver Injury: Understanding the Different Immune-Mediated Phenotypes and Clinical Management","year":2018,"lang":"en","type":"article","venue":"Current Hepatology Reports","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Alberta Innovates - Health Solutions","keywords":"Phenotype; Liver injury; Immune system; Medicine; Drug; Immunology; Biology; Pharmacology; Gene; Genetics","score_opus":0.22131572657727322,"score_gpt":0.4542068309316119,"score_spread":0.23289110435433868,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2809242708","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9796843,0.0010525354,0.00041028438,0.0008774859,0.012655891,0.0011517958,0.000011062736,0.00020293253,0.0039537307],"genre_scores_gemma":[0.9965381,0.0017848511,0.000021717791,0.00064703944,0.0006429744,0.000102342674,0.000028770013,0.00003136953,0.00020285105],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961935,0.0012186412,0.0009988658,0.00072800205,0.00022022318,0.0006407582],"domain_scores_gemma":[0.9980632,0.0005291328,0.0005506484,0.00049899984,0.00010233589,0.00025567407],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0019320743,0.00037656422,0.0005234313,0.00016690562,0.0009817581,0.000043727236,0.00023926634,0.0004706956,0.00050721],"category_scores_gemma":[0.00016742882,0.00028158058,0.00017759862,0.00026487096,0.0009017412,0.00012693091,0.0003431265,0.001525143,0.000154455],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010481633,0.001733929,0.69859314,0.00033245675,0.0015377688,0.00083255314,0.0032047145,0.0000010562593,0.0032353548,0.0134624615,0.013953131,0.26206526],"study_design_scores_gemma":[0.0060011344,0.001480644,0.15332437,0.00035668578,0.0028316656,0.0020639102,0.0016990318,0.0116058355,0.029129997,0.033547338,0.7550723,0.0028871256],"about_ca_topic_score_codex":0.00003679322,"about_ca_topic_score_gemma":0.0001391156,"teacher_disagreement_score":0.74111915,"about_ca_system_score_codex":0.00018931138,"about_ca_system_score_gemma":0.00007010672,"threshold_uncertainty_score":0.99996364},"labels":[],"label_agreement":null},{"id":"W2883978174","doi":"10.4212/cjhp.v52i1.1765","title":"Amoxicillin-clavulanic acid-induced hepatotoxicity","year":2018,"lang":"en","type":"article","venue":"The Canadian Journal of Hospital Pharmacy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Clavulanic acid; Amoxicillin; Amoxicillin/clavulanic acid; Medicine; Beta-Lactamase Inhibitors; Pharmacology; Chemistry; Antibiotics; Biochemistry","score_opus":0.13185139207814986,"score_gpt":0.4059190004581187,"score_spread":0.2740676083799688,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2883978174","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97515446,0.00049530814,0.0000871269,0.0071088294,0.008734375,0.0005615921,0.000046366273,0.000042903142,0.007769039],"genre_scores_gemma":[0.9919643,0.000075143515,0.000059450635,0.0042513264,0.0033049702,0.000014918421,0.0000033917597,0.00004748947,0.00027903216],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970182,0.00071383535,0.0007464658,0.00026944716,0.0003520099,0.00090005086],"domain_scores_gemma":[0.9969939,0.00017724035,0.00057676114,0.00031840798,0.0006794719,0.001254233],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0022304133,0.00035784213,0.00041147688,0.00032708052,0.0016256054,0.00013244007,0.0010471866,0.00029403187,0.002293663],"category_scores_gemma":[0.000326629,0.00027761929,0.00030872703,0.0005526204,0.0006593613,0.00046979505,0.00005296865,0.0023792384,0.0007060863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018517806,0.0012704442,0.085578434,0.00015823965,0.0029871617,0.0022150122,0.02665798,0.00023901118,0.6013736,0.0069095776,0.09105915,0.17969961],"study_design_scores_gemma":[0.0028585612,0.0013684504,0.0035430507,0.000050430463,0.00028834524,0.0004303604,0.00026107888,0.001086787,0.66631716,0.0035493139,0.31962422,0.0006222208],"about_ca_topic_score_codex":0.0064798626,"about_ca_topic_score_gemma":0.022896169,"teacher_disagreement_score":0.22856505,"about_ca_system_score_codex":0.0005086516,"about_ca_system_score_gemma":0.0017007632,"threshold_uncertainty_score":0.9999676},"labels":[],"label_agreement":null},{"id":"W2884517754","doi":"10.1124/dmd.118.082719","title":"Do In Vitro Assays Predict Drug Candidate Idiosyncratic Drug-Induced Liver Injury Risk?","year":2018,"lang":"en","type":"review","venue":"Drug Metabolism and Disposition","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Metabolite; Mechanism (biology); Drug; Liver injury; Cytotoxicity; In vitro toxicology; Biology; Pharmacology; In vitro; Drug development; Computational biology; Biochemistry","score_opus":0.06305219569152005,"score_gpt":0.3899189201407313,"score_spread":0.3268667244492113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2884517754","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06312568,0.9254666,0.00003127918,0.00007785889,0.00418221,0.0030649493,0.0022244933,0.00020954158,0.0016174049],"genre_scores_gemma":[0.087100685,0.9086383,0.00007186108,0.00029158115,0.0017221215,0.0007322636,0.00088905415,0.00011548008,0.0004386286],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9909973,0.004996855,0.0013557258,0.0012643411,0.00043057703,0.0009551837],"domain_scores_gemma":[0.9971724,0.0005709006,0.0010040911,0.000605669,0.00013718977,0.00050970906],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0035689694,0.0010874019,0.0022682485,0.0008711859,0.0008223047,0.0001840847,0.00050464657,0.0012091186,0.00025906734],"category_scores_gemma":[0.00015986753,0.0009851103,0.0005554418,0.00087675813,0.0002662272,0.0006373318,0.00025346168,0.0032238087,0.00040961447],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052833295,0.00051440945,0.00005706622,0.0062329457,0.0004705886,0.000082181614,0.0022891797,0.0000022422894,0.00085435313,0.00036133753,0.004112421,0.9844949],"study_design_scores_gemma":[0.001723873,0.00004758229,0.0002076178,0.0023532852,0.0041391784,0.000081480066,0.00011832517,0.00049292593,0.0065778773,0.0007987397,0.9820621,0.0013970311],"about_ca_topic_score_codex":0.00086905377,"about_ca_topic_score_gemma":0.00025832898,"teacher_disagreement_score":0.9830979,"about_ca_system_score_codex":0.00025065037,"about_ca_system_score_gemma":0.0003312483,"threshold_uncertainty_score":0.99925995},"labels":[],"label_agreement":null},{"id":"W2885850456","doi":"10.1186/s12887-018-1233-5","title":"A case report of full recovery from severe cerebral edema secondary to acetaminophen-induced hepatotoxicity in a 13 year old girl","year":2018,"lang":"en","type":"article","venue":"BMC Pediatrics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Western University; Muscular Dystrophy Canada; University of Toronto","funders":"","keywords":"Medicine; Acetaminophen; Cerebral edema; Liver failure; Edema; Complication; Liver transplantation; Anesthesia; Toxicity; Girl; Surgery; Internal medicine; Transplantation","score_opus":0.09642250562612777,"score_gpt":0.3649788313609094,"score_spread":0.26855632573478166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2885850456","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99093556,0.000072789546,0.00054637884,0.00018387278,0.0026238048,0.0011288424,0.00047856252,0.00012489132,0.0039052737],"genre_scores_gemma":[0.9937881,0.00003070469,0.002147459,0.00093882746,0.0021408414,0.000108775945,0.00005452699,0.00005260493,0.0007381115],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965482,0.00072411523,0.00092323386,0.0007850465,0.00032693843,0.00069251214],"domain_scores_gemma":[0.9976594,0.00061117834,0.00048537288,0.00057359244,0.0002498141,0.00042068164],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0016184503,0.00039816432,0.0006080321,0.0004891508,0.00025518282,0.000032155545,0.0003377144,0.0010213197,0.001289194],"category_scores_gemma":[0.0006699474,0.00044286717,0.000214643,0.0010471852,0.00010949878,0.00030700897,0.00027061556,0.0013460381,0.00041472344],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008153624,0.0031097517,0.74427503,0.0011935169,0.00045138155,0.028154293,0.011057775,0.00079132937,0.14666288,0.00024369705,0.032217488,0.023689259],"study_design_scores_gemma":[0.03615345,0.008667283,0.19961692,0.00029359144,0.002398404,0.049721733,0.005172815,0.009591016,0.60576963,0.007841506,0.065920256,0.008853416],"about_ca_topic_score_codex":0.0019919034,"about_ca_topic_score_gemma":0.007034905,"teacher_disagreement_score":0.5446581,"about_ca_system_score_codex":0.00027374303,"about_ca_system_score_gemma":0.0005466193,"threshold_uncertainty_score":0.9998023},"labels":[],"label_agreement":null},{"id":"W2888195361","doi":"10.1002/hep.30224","title":"The NACSTOP Trial: A Multicenter, Cluster‐Controlled Trial of Early Cessation of Acetylcysteine in Acetaminophen Overdose","year":2018,"lang":"en","type":"article","venue":"Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Health and Medical Research Council; Medical Research Council","keywords":"Medicine; Acetaminophen; Acetylcysteine; acetaminophen overdose; Interquartile range; Incidence (geometry); Regimen; Adverse effect; Internal medicine; Anesthesia; Gastroenterology","score_opus":0.09325552395835801,"score_gpt":0.41845338669723536,"score_spread":0.32519786273887735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2888195361","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.988275,0.00018448835,0.000089885296,0.0007422581,0.0044072047,0.004208423,0.00001557111,0.000036830377,0.002040374],"genre_scores_gemma":[0.9980966,0.000194083,0.000054225377,0.00028475432,0.0005059884,0.0004649137,0.000006416603,0.000019790448,0.0003732555],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.995508,0.002393343,0.0011458268,0.00031085665,0.00020081943,0.00044113636],"domain_scores_gemma":[0.9971027,0.001475865,0.0007749541,0.0003416878,0.00022159974,0.000083190585],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0024540229,0.00022344376,0.00078192947,0.0002190748,0.00021373715,0.000010002915,0.00035199244,0.000653567,0.0001380168],"category_scores_gemma":[0.000752849,0.00017511165,0.00019850822,0.0003481285,0.0005642796,0.0001292221,0.00010709535,0.0006287341,0.000038291375],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.95676917,0.0011014614,0.007891578,0.00006145696,0.00023563289,0.0000060900657,0.001989807,0.000016429163,0.01944269,0.0013303632,0.0001731369,0.010982162],"study_design_scores_gemma":[0.9124883,0.003871159,0.00060942525,0.000027295093,0.0001761598,0.000009185308,0.00013194239,0.010887992,0.059301313,0.000786431,0.011499524,0.00021129582],"about_ca_topic_score_codex":0.00047383152,"about_ca_topic_score_gemma":0.001039692,"teacher_disagreement_score":0.044280916,"about_ca_system_score_codex":0.00009111387,"about_ca_system_score_gemma":0.00016499656,"threshold_uncertainty_score":0.71408457},"labels":[],"label_agreement":null},{"id":"W2888309806","doi":"10.14740/jmc.v9i9.3108","title":"A Delayed Case of Black Cohosh Associated Drug-Induced Liver Injury","year":2018,"lang":"en","type":"article","venue":"Journal of Medical Cases","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Black cohosh; Medicine; Liver injury; Drug; Acetaminophen; Culprit; Traditional medicine; Internal medicine; Pharmacology","score_opus":0.14014240915843684,"score_gpt":0.45205078963049533,"score_spread":0.3119083804720585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2888309806","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951329,0.00020153783,0.000076318065,0.0013785652,0.002121584,0.00020760446,0.000051862364,0.000026448331,0.00080314686],"genre_scores_gemma":[0.9965294,0.00029427445,0.00005285213,0.0016599592,0.0013063003,0.0000039265474,0.0000027820993,0.000018758737,0.00013174217],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967306,0.001130556,0.0009160639,0.0001644821,0.00070216705,0.00035608828],"domain_scores_gemma":[0.9966258,0.0011491263,0.0008480036,0.00013344512,0.00066411647,0.00057953823],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.003990507,0.00019481716,0.00049795286,0.00022850347,0.00022092507,0.000014621668,0.0003206357,0.00073860947,0.0033115821],"category_scores_gemma":[0.0032284167,0.00016362095,0.00022886427,0.0003585858,0.0005083007,0.00017548543,0.000087132,0.0017985885,0.000077892175],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012756781,0.009754157,0.01255115,0.0006173729,0.005012874,0.15208344,0.018754613,0.00004405913,0.14894518,0.0014462207,0.25672933,0.38130483],"study_design_scores_gemma":[0.0147815,0.011146952,0.002811446,0.00089752045,0.00210704,0.07242726,0.003318389,0.013497683,0.76671714,0.0014029525,0.109639116,0.0012530261],"about_ca_topic_score_codex":0.00039631833,"about_ca_topic_score_gemma":0.00053191435,"teacher_disagreement_score":0.6177719,"about_ca_system_score_codex":0.00013287911,"about_ca_system_score_gemma":0.00046978795,"threshold_uncertainty_score":0.99759954},"labels":[],"label_agreement":null},{"id":"W2894666062","doi":"10.1016/j.toxlet.2018.09.014","title":"Chlordecone potentiates auto-immune hepatitis and promotes brain entry of MHV3 during viral hepatitis in mouse models","year":2018,"lang":"en","type":"article","venue":"Toxicology Letters","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Agence Nationale de la Recherche","keywords":"Mouse hepatitis virus; Hepatitis; Concanavalin A; Immune system; Liver injury; Immunology; Virus; Toxic hepatitis; Inflammation; Medicine; Viral hepatitis; Virology; Biology; Pharmacology; Pathology; Biochemistry","score_opus":0.041289670566690424,"score_gpt":0.3311188415441708,"score_spread":0.2898291709774804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2894666062","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99151105,0.00021148576,0.00028434792,0.005462354,0.0008108768,0.0008606988,0.0000724721,0.00013370921,0.00065300293],"genre_scores_gemma":[0.99468637,0.00036795673,0.0003619826,0.0037242821,0.00023572605,0.00013919143,0.000022649514,0.000041994415,0.00041988093],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971743,0.0007098307,0.0007043603,0.0005388077,0.00014990865,0.000722764],"domain_scores_gemma":[0.998924,0.00028582796,0.00029950778,0.00026236242,0.000070695794,0.00015759935],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007909433,0.0003407275,0.00056650385,0.00040182762,0.00032885734,0.00002347611,0.00027429487,0.0006352314,0.00053510803],"category_scores_gemma":[0.0001269604,0.00038283164,0.00010424817,0.00026711772,0.00084564445,0.00040038038,0.00019088085,0.00096175686,0.000052045365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036504166,0.00033254977,0.06629735,0.00013123316,0.00015549068,0.00007039153,0.0019635053,0.00028103797,0.9264505,0.00042526747,0.00025205442,0.003275556],"study_design_scores_gemma":[0.0033870914,0.0005002254,0.08455891,0.000053761127,0.0000641332,0.000097630684,0.000052431238,0.013290768,0.8954319,0.0014126218,0.0006611875,0.0004893471],"about_ca_topic_score_codex":0.0010737748,"about_ca_topic_score_gemma":0.0011848045,"teacher_disagreement_score":0.031018626,"about_ca_system_score_codex":0.00014825497,"about_ca_system_score_gemma":0.000053610478,"threshold_uncertainty_score":0.9998624},"labels":[],"label_agreement":null},{"id":"W2896117584","doi":"10.1039/c8fo01078a","title":"Polydatin protects against acetaminophen-induced hepatotoxicity in mice <i>via</i> anti-oxidative and anti-apoptotic activities","year":2018,"lang":"en","type":"article","venue":"Food & Function","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Drug Research and Development","funders":"Department of Education of Guangdong Province","keywords":"Acetaminophen; Pharmacology; Apoptosis; Chemistry; Oxidative stress; Oxidative phosphorylation; Oxidative damage; Medicine; Biochemistry","score_opus":0.07994432030307214,"score_gpt":0.3477601608256778,"score_spread":0.26781584052260565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2896117584","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917413,0.00010889982,0.00072811614,0.0002857527,0.0021282972,0.0017749498,0.000047342182,0.00025277646,0.002932595],"genre_scores_gemma":[0.99748147,0.000079434256,0.00010195255,0.0011951685,0.0007205732,0.00025773293,0.000036206467,0.000050636212,0.000076808086],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967969,0.00096821174,0.00050877174,0.0007429612,0.0002612686,0.0007218698],"domain_scores_gemma":[0.9988225,0.00024357864,0.00031827614,0.0002637533,0.00012955276,0.00022234242],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010373937,0.0004585488,0.00050500315,0.0003824106,0.0006975309,0.00006721925,0.00019131259,0.00074147753,0.00021952379],"category_scores_gemma":[0.00015216663,0.0004833401,0.00009600122,0.0006907626,0.0003158877,0.0007115093,0.00013620147,0.0014600428,0.0001759026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019864962,0.0004615835,0.00743757,0.00012061451,0.00017604568,0.000009084786,0.0016146167,0.000036746023,0.9568672,0.00015358606,0.00007866778,0.031057764],"study_design_scores_gemma":[0.0024391513,0.005294867,0.020986719,0.00008037479,0.0000879246,0.000032754186,0.000566242,0.002431129,0.96367544,0.00046467668,0.0033191761,0.0006215202],"about_ca_topic_score_codex":0.00017128886,"about_ca_topic_score_gemma":0.00043616787,"teacher_disagreement_score":0.030436244,"about_ca_system_score_codex":0.00017652851,"about_ca_system_score_gemma":0.00011488435,"threshold_uncertainty_score":0.9997618},"labels":[],"label_agreement":null},{"id":"W2897528830","doi":"10.2147/dddt.s172487","title":"Antioxidative stress effects of vitamins C, E, and B&lt;sub&gt;12&lt;/sub&gt;, and their combination can protect the liver against acetaminophen-induced hepatotoxicity in rats","year":2018,"lang":"en","type":"article","venue":"Drug Design Development and Therapy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"College of Pharmacy and Nutrition, University of Saskatchewan; University of Petra","keywords":"Acetaminophen; Oxidative stress; Pharmacology; Vitamin E; In vivo; Antioxidant; Chemistry; Hepatocyte; Glutathione; Vitamin C; Lipid peroxidation; Superoxide dismutase; Hepatoprotection; Liver injury; Biochemistry; In vitro; Enzyme; Medicine; Biology","score_opus":0.06731345294423799,"score_gpt":0.31041097095283504,"score_spread":0.24309751800859705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897528830","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942097,0.0013270566,0.0005185351,0.00021319088,0.00032369525,0.0031713508,0.000015185392,0.000056471563,0.00016479095],"genre_scores_gemma":[0.99449897,0.0043299883,0.00017496268,0.0004518013,0.00007877432,0.00036784355,0.000015282203,0.00003172674,0.000050673298],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99694425,0.001477027,0.00043764248,0.0005031773,0.00019736821,0.00044055126],"domain_scores_gemma":[0.99849194,0.0007570768,0.00028397603,0.00017651134,0.00014467839,0.00014584167],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0016511607,0.00042784796,0.000454581,0.00024759484,0.00067743886,0.00005755287,0.00019359116,0.00035251916,0.000011743699],"category_scores_gemma":[0.000067387526,0.00032175164,0.000042736305,0.00033657058,0.0004463837,0.0002262572,0.000099913574,0.0005856079,0.000004463745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045828588,0.00033038048,0.0038519274,0.00012510733,0.00018856696,0.000011018578,0.019782161,0.0000028315471,0.7588941,0.00013852736,0.000034297613,0.21618278],"study_design_scores_gemma":[0.0029800048,0.00033870147,0.041495588,0.00013029137,0.00002096212,0.000007375349,0.00021633864,0.0015047617,0.9514976,0.00049358146,0.00093679497,0.00037799522],"about_ca_topic_score_codex":0.000031451007,"about_ca_topic_score_gemma":0.0003410229,"teacher_disagreement_score":0.21580479,"about_ca_system_score_codex":0.00008762668,"about_ca_system_score_gemma":0.00015754622,"threshold_uncertainty_score":0.99992347},"labels":[],"label_agreement":null},{"id":"W2898152099","doi":"10.1371/journal.pone.0206389","title":"Cytokine profiles in acute liver injury—Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group","year":2018,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Yale Liver Center; Duke Clinical Research Institute; National Institute of Diabetes and Digestive and Kidney Diseases; University of North Carolina at Chapel Hill; Claude Pepper Older Americans Independence Center, Wake Forest School of Medicine; U.S. Public Health Service; National Institutes of Health; University of Alberta; University of California, Los Angeles; University of South Carolina; University of Texas Southwestern Medical Center; Wake Forest University; Yale University; Virginia Commonwealth University; University of Kansas; Northwestern University; University of Washington; National Cancer Institute; Emory University; Purdue University; National Center for Advancing Translational Sciences; University of Southern California","keywords":"Medicine; Liver injury; Internal medicine; Acetaminophen; Gastroenterology; Albumin; Liver disease; Chemokine; Drug; Etiology; Immune system; Cohort; Immunology; Inflammation; Pharmacology","score_opus":0.09122326170227946,"score_gpt":0.3401985620602797,"score_spread":0.24897530035800025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898152099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913582,0.00037146377,0.000009029387,0.002123327,0.00068577036,0.0042727008,0.0006137182,0.00015555932,0.00041023784],"genre_scores_gemma":[0.9916032,0.0013345246,0.00026734298,0.003322333,0.0023845478,0.0005324688,0.00007688117,0.0000577286,0.00042096732],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99452966,0.002670069,0.0007209828,0.00082976505,0.00046604057,0.0007834552],"domain_scores_gemma":[0.9972526,0.0013119469,0.0003696842,0.0006588109,0.00020859778,0.00019838863],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0024409115,0.00052330067,0.000682929,0.000116308176,0.0011055522,0.000115541596,0.00071902084,0.0005871223,0.0003940444],"category_scores_gemma":[0.00018292181,0.00035335164,0.0001259239,0.00064007845,0.000696125,0.0003765555,0.00054389593,0.0024411357,0.00038873267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.11555067,0.031712554,0.14733264,0.0003389739,0.029368572,0.0013727344,0.15680723,0.000088305474,0.39303425,0.002210008,0.043916456,0.07826761],"study_design_scores_gemma":[0.06086534,0.007820414,0.26414308,0.0010578061,0.016012987,0.00008397059,0.0035853127,0.061093938,0.5376204,0.0035904457,0.039677445,0.00444882],"about_ca_topic_score_codex":0.0018511432,"about_ca_topic_score_gemma":0.004672267,"teacher_disagreement_score":0.1532219,"about_ca_system_score_codex":0.000113298076,"about_ca_system_score_gemma":0.000077356446,"threshold_uncertainty_score":0.9998918},"labels":[],"label_agreement":null},{"id":"W2898201847","doi":"10.11144/javeriana.umed59-4.acet","title":"Actualización en la comprensión y manejo de la intoxicación por acetaminofén","year":2018,"lang":"es","type":"article","venue":"Universitas Médica","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Encana (Canada)","funders":"","keywords":"Medicine; Gynecology; Humanities; Philosophy","score_opus":0.03954173500827369,"score_gpt":0.3910582564533275,"score_spread":0.3515165214450538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898201847","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.72906023,0.00044726545,0.00095428934,0.0017671214,0.001650982,0.0006981055,0.00027091452,0.0003558141,0.26479527],"genre_scores_gemma":[0.99117374,0.0010998633,0.00051367225,0.0020732055,0.0011876319,0.000008919892,0.000056755584,0.00006530797,0.0038208852],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9935073,0.0041409717,0.00040208353,0.00068874017,0.00030941673,0.00095143635],"domain_scores_gemma":[0.9970662,0.0013654392,0.00029397948,0.00045973973,0.00018102297,0.0006336077],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0017816562,0.0005599428,0.00054249715,0.00047428795,0.0011378169,0.00013171525,0.00076107285,0.0020961682,0.008728653],"category_scores_gemma":[0.00019711468,0.0006461895,0.000279448,0.0005601542,0.0019990446,0.0003537333,0.00043159627,0.0023252282,0.0018761909],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006054817,0.005442551,0.043493457,0.0012963649,0.004918278,0.004274931,0.047755633,0.00028956975,0.2737718,0.21847616,0.23777838,0.15644805],"study_design_scores_gemma":[0.0029104922,0.00053259725,0.008753802,0.00013056437,0.00085835124,0.00033527357,0.0024069864,0.0017626114,0.05770274,0.0009479795,0.92291224,0.0007463453],"about_ca_topic_score_codex":0.00015343868,"about_ca_topic_score_gemma":0.000016628388,"teacher_disagreement_score":0.6851339,"about_ca_system_score_codex":0.0005203545,"about_ca_system_score_gemma":0.00044224065,"threshold_uncertainty_score":0.99997646},"labels":[],"label_agreement":null},{"id":"W2898453518","doi":"10.1096/fasebj.23.1_supplement.760.2","title":"Nrf2‐disrupted mice exhibits heightened liver injury induced by lithocholic acid","year":2009,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Lithocholic acid; Liver injury; Bile acid; Glutathione; Oxidative stress; Alkaline phosphatase; Cholestasis; Biology; Chemistry; Biochemistry; Pharmacology; Internal medicine; Endocrinology; Medicine; Enzyme","score_opus":0.09265740972435514,"score_gpt":0.3883406909928468,"score_spread":0.29568328126849164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898453518","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9879917,0.0009741741,0.00021473516,0.00404507,0.0014800356,0.00045951325,0.000049570324,0.00011068789,0.004674502],"genre_scores_gemma":[0.98757035,0.0007087566,0.000092634196,0.009667647,0.0010334433,0.000015706291,0.000013424295,0.000024721296,0.0008733395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99682903,0.0013657741,0.0005068835,0.0002921741,0.0003155838,0.00069055206],"domain_scores_gemma":[0.9986452,0.0001643439,0.0003419674,0.00025886067,0.00016372852,0.00042589864],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0017916796,0.00033399442,0.0003123055,0.00016090611,0.0013288179,0.0001184641,0.00057696813,0.0005542133,0.0012487979],"category_scores_gemma":[0.00011539553,0.00024942326,0.00019777293,0.00041157313,0.00011677903,0.00037928962,0.000057745256,0.003285428,0.0006213495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005736667,0.00028039748,0.000112871516,0.000006774593,0.000109528344,0.00005017887,0.0012300506,0.000013361357,0.9134943,0.00015809275,0.007223167,0.07674761],"study_design_scores_gemma":[0.0014583375,0.00045487683,0.0012816128,0.000029525072,0.0001396218,0.0006290845,0.000117531745,0.0005371174,0.9634552,0.0014490988,0.030099561,0.00034843982],"about_ca_topic_score_codex":0.000021349415,"about_ca_topic_score_gemma":0.000007837443,"teacher_disagreement_score":0.07639917,"about_ca_system_score_codex":0.0001845745,"about_ca_system_score_gemma":0.00012128205,"threshold_uncertainty_score":0.9999958},"labels":[],"label_agreement":null},{"id":"W2902053966","doi":"10.3390/cells7120247","title":"Paradoxical Role of Matrix Metalloproteinases in Liver Injury and Regeneration after Sterile Acute Hepatic Failure","year":2018,"lang":"en","type":"article","venue":"Cells","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Calgary","funders":"Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Fundação de Desenvolvimento da Pesquisa; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Liver injury; Matrix metalloproteinase; Medicine; Acetaminophen; Inflammation; Matrix metalloproteinase inhibitor; Pharmacology; Necrosis; Intravital microscopy; Hepatocyte; Immunology; Pathology; Biology; Microcirculation; Internal medicine; Biochemistry","score_opus":0.03494421892849427,"score_gpt":0.36423209013364805,"score_spread":0.3292878712051538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902053966","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980261,0.00046189575,0.00009127191,0.000121170306,0.0003096735,0.0005200919,0.000049460847,0.00002593755,0.00039442556],"genre_scores_gemma":[0.9982419,0.00021184991,0.00060096476,0.00024305988,0.00020405695,0.00010342784,0.000008108818,0.000013308608,0.00037332665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99883854,0.0003327765,0.0002755596,0.00023655468,0.00009417383,0.0002223751],"domain_scores_gemma":[0.99956536,0.000061467836,0.00009619358,0.00013491677,0.000053359556,0.00008871643],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035039862,0.00014669029,0.00022179537,0.000116441115,0.0000864495,0.000015419388,0.00008500577,0.00031958093,0.0007438752],"category_scores_gemma":[0.0000148929785,0.0001412857,0.00004768423,0.00016165151,0.00019082452,0.00016102468,0.00006129654,0.00033425767,0.00011260452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006020571,0.00015940204,0.0022158518,0.00006728131,0.00005800433,0.000018596225,0.0009555798,0.000010081942,0.9824215,0.00015304254,0.00019510882,0.01314349],"study_design_scores_gemma":[0.00046129434,0.00028730175,0.0018165116,0.000022044236,0.00008182413,0.000010088318,0.000052481493,0.0030976685,0.97639656,0.0006624957,0.01695538,0.00015632175],"about_ca_topic_score_codex":0.00006452411,"about_ca_topic_score_gemma":0.00018712343,"teacher_disagreement_score":0.016760271,"about_ca_system_score_codex":0.000030879364,"about_ca_system_score_gemma":0.000030992767,"threshold_uncertainty_score":0.8144912},"labels":[],"label_agreement":null},{"id":"W2906150895","doi":"10.4212/cjhp.v52i3.1802","title":"Ranitidine prescribing practices at a community hospital","year":2018,"lang":"en","type":"article","venue":"The Canadian Journal of Hospital Pharmacy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Ranitidine; Medicine; Pharmacology","score_opus":0.20695220514006854,"score_gpt":0.42978462259416583,"score_spread":0.2228324174540973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2906150895","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9673791,0.00056667917,0.000017677268,0.0140377125,0.006621905,0.00053662807,0.00005600955,0.000029924382,0.010754396],"genre_scores_gemma":[0.9948875,0.000096906784,0.000053625805,0.002171967,0.002229746,0.000013354746,0.00000589028,0.000035724603,0.0005053036],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967743,0.0015915104,0.00055801985,0.00015822555,0.00026216405,0.0006557643],"domain_scores_gemma":[0.99655885,0.00053152663,0.0011466142,0.00028794692,0.00061913865,0.00085594715],"candidate_categories":["sts","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0031965817,0.00026896063,0.00029978805,0.00021178537,0.0033555126,0.00013910249,0.0009623765,0.00017612142,0.0017434177],"category_scores_gemma":[0.0009836913,0.00021324924,0.00020051519,0.00032114345,0.000866591,0.0007215572,0.0001033993,0.0030633733,0.00032260298],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0050420705,0.0038489883,0.24397121,0.00041497688,0.005535903,0.0025912363,0.19023997,0.00047202763,0.09859224,0.0047165873,0.32869136,0.115883425],"study_design_scores_gemma":[0.004513427,0.0026493245,0.0070358915,0.000090841546,0.00056898437,0.000670998,0.0017466749,0.00061994715,0.1360264,0.0026704965,0.84272325,0.00068374973],"about_ca_topic_score_codex":0.021004505,"about_ca_topic_score_gemma":0.04579794,"teacher_disagreement_score":0.5140319,"about_ca_system_score_codex":0.0005294204,"about_ca_system_score_gemma":0.0009756714,"threshold_uncertainty_score":0.9992366},"labels":[],"label_agreement":null},{"id":"W2907552518","doi":"10.4212/cjhp.v71i6.2851","title":"Safety of Rectal Administration of Acetaminophen in Neonates","year":2019,"lang":"en","type":"article","venue":"The Canadian Journal of Hospital Pharmacy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; Joseph Brant Hospital; Hospital for Sick Children","funders":"","keywords":"Medicine; Acetaminophen; Interquartile range; Antipyretic; Rectal administration; Gestational age; Nephrotoxicity; Anesthesia; Renal function; Analgesic; Pregnancy; Internal medicine; Toxicity","score_opus":0.05875874769998199,"score_gpt":0.36917453184448235,"score_spread":0.31041578414450033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2907552518","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910105,0.0005049328,0.0000058733144,0.002137173,0.00188272,0.00042631492,0.000051439773,0.0000035683386,0.003977504],"genre_scores_gemma":[0.9993449,0.000103391445,0.000035123398,0.0001913721,0.00014327237,0.0000032555895,0.000004083444,0.000012482559,0.00016212728],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998431,0.00036460912,0.0006614936,0.00010324756,0.0001665121,0.00027308668],"domain_scores_gemma":[0.9986533,0.00021748929,0.00055900094,0.00011829473,0.00021241038,0.00023948656],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013499075,0.00013574112,0.000305663,0.00023415002,0.00010322211,0.000011655742,0.00037155673,0.00012812334,0.0008456314],"category_scores_gemma":[0.000112928275,0.00011160679,0.00013535802,0.00028469542,0.00019519367,0.0002470277,0.000016639342,0.00093289616,0.000024847877],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0070229163,0.0010836469,0.59207577,0.0005528357,0.001234758,0.0004857004,0.023834178,0.0066760783,0.22681226,0.005808748,0.00247924,0.13193385],"study_design_scores_gemma":[0.008590098,0.0024149795,0.08438321,0.00023374466,0.00027591368,0.00029162897,0.0012444147,0.0016764045,0.83654714,0.0035862986,0.060215518,0.00054066745],"about_ca_topic_score_codex":0.003630116,"about_ca_topic_score_gemma":0.007351555,"teacher_disagreement_score":0.60973483,"about_ca_system_score_codex":0.00016677259,"about_ca_system_score_gemma":0.0011201905,"threshold_uncertainty_score":0.9259071},"labels":[],"label_agreement":null},{"id":"W2908525626","doi":"10.1002/cpt.1375","title":"Drug‐Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles","year":2019,"lang":"en","type":"article","venue":"Clinical Pharmacology & Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"NIHR Nottingham Biomedical Research Centre; European Regional Development Fund; Medical Research Council; Svenska Läkaresällskapet; Uppsala Universitet; Radboud Universitair Medisch Centrum; Karolinska Institutet; University of Nottingham; King's College London; Daiichi-Sankyo; Abbott Laboratories; National Institute for Health and Care Research; Biotechnology and Biological Sciences Research Council; Wellcome Trust; Nottingham University Hospitals NHS Trust; King’s College London; Roche; Instituto de Salud Carlos III; Amgen; Radboud Universiteit; Newcastle University; Novartis; AstraZeneca; Vetenskapsrådet; University of Warwick; Pfizer; Merck; Directorate for Biological Sciences; GlaxoSmithKline; Sanofi; Wellcome; Universiteit Utrecht","keywords":"Flucloxacillin; Human leukocyte antigen; Odds ratio; Allele; Medicine; Immunology; Penicillin; HLA-B; Genotype; Internal medicine; Biology; Antigen; Antibiotics; Gene; Genetics; Staphylococcus aureus","score_opus":0.22223027141294577,"score_gpt":0.4858570597651821,"score_spread":0.26362678835223635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2908525626","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9855313,0.00048163204,0.0001208716,0.0024536285,0.007758039,0.0022367788,0.000086687214,0.0002368648,0.0010942442],"genre_scores_gemma":[0.95376104,0.0016086308,0.00040989995,0.04180075,0.0011218624,0.00011985278,0.00002869869,0.000092028036,0.0010572625],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9937172,0.0022935905,0.0016775451,0.0009954215,0.0003402876,0.0009759822],"domain_scores_gemma":[0.99534726,0.0024886054,0.00064643484,0.0005999317,0.0003970376,0.0005207397],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0026469058,0.0005735497,0.0011877031,0.00026595275,0.00042190883,0.000020988877,0.00096963916,0.0012267818,0.0022905245],"category_scores_gemma":[0.000094021154,0.000584979,0.0004887909,0.0005295268,0.00051479833,0.00021170033,0.00033907226,0.0028267964,0.0017347597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027289232,0.0017514102,0.035256185,0.0001442407,0.0012763253,0.00006388099,0.0011537804,0.00043853297,0.9082081,0.00011645879,0.009260171,0.039602038],"study_design_scores_gemma":[0.0042809495,0.0011881934,0.012387863,0.000038093138,0.0004576659,0.000017269553,0.00011122213,0.0030454616,0.6008505,0.00027402674,0.37665418,0.00069455715],"about_ca_topic_score_codex":0.000057860536,"about_ca_topic_score_gemma":0.0000651764,"teacher_disagreement_score":0.367394,"about_ca_system_score_codex":0.00015621954,"about_ca_system_score_gemma":0.00024747965,"threshold_uncertainty_score":0.99966013},"labels":[],"label_agreement":null},{"id":"W2908736094","doi":"10.1016/bs.apha.2018.12.001","title":"Mechanisms of idiosyncratic drug-induced liver injury","year":2019,"lang":"en","type":"review","venue":"Advances in pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":58,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Metabolite; Immune system; Mechanism (biology); Biology; Drug; Computational biology; Immunology; Pharmacology; Biochemistry","score_opus":0.1711743122891088,"score_gpt":0.49999759872207594,"score_spread":0.32882328643296715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2908736094","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00044664188,0.9767286,0.00014555523,0.00004536387,0.013872923,0.0037231268,0.00019608793,0.00012599619,0.004715689],"genre_scores_gemma":[0.0074409433,0.9895215,0.00022164643,0.00068462663,0.000419707,0.0009112006,0.0000711345,0.00012677159,0.00060247764],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99252695,0.0032513267,0.0018151934,0.0010610435,0.0003094978,0.0010359894],"domain_scores_gemma":[0.9961007,0.0016392996,0.0014076781,0.0004761646,0.00013351564,0.0002426074],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0017543193,0.0009617479,0.0032924255,0.0009864686,0.00016865098,0.000012488958,0.0010824316,0.0017726927,0.0020630301],"category_scores_gemma":[0.00010428734,0.00093557057,0.000666516,0.0011255076,0.00027089327,0.0005203364,0.0003418033,0.0039151604,0.00094559713],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018663592,0.0005104804,0.0000074173154,0.022459282,0.00035943562,0.000109896144,0.00018114374,0.000067426314,0.0030318177,0.0023250151,0.00063961965,0.9701218],"study_design_scores_gemma":[0.0012194796,0.0002943638,0.0000011461802,0.0016786853,0.001594242,0.00007848584,0.000029432755,0.00025703528,0.012946037,0.0020010439,0.97905576,0.00084430637],"about_ca_topic_score_codex":0.000030200967,"about_ca_topic_score_gemma":0.000048129747,"teacher_disagreement_score":0.97841614,"about_ca_system_score_codex":0.0004731268,"about_ca_system_score_gemma":0.000611299,"threshold_uncertainty_score":0.9998323},"labels":[],"label_agreement":null},{"id":"W2911369805","doi":"10.5694/j.1326-5377.2003.tb05514.x","title":"The effect of recalling paracetamol on hospital admissions for poisoning","year":2003,"lang":"en","type":"article","venue":"The Medical Journal of Australia","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Citation; Library science; Psychology; Sociology; History; Computer science","score_opus":0.14054754799094207,"score_gpt":0.48330578264368884,"score_spread":0.3427582346527468,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911369805","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98825204,0.00017594508,0.0005475506,0.0072962116,0.0029554998,0.00046181542,0.0000047430963,0.000008242986,0.00029792055],"genre_scores_gemma":[0.9986536,0.00014380837,0.000076076845,0.0002034487,0.00045857584,0.00001695417,5.1841613e-7,0.000010097605,0.0004369048],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974188,0.0012923735,0.0005152024,0.00008983189,0.00038502747,0.00029873117],"domain_scores_gemma":[0.99532413,0.0037018086,0.000423677,0.00011636144,0.00009334452,0.00034067617],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00657719,0.00013420722,0.0002641703,0.00004314593,0.00047269548,0.0000146572365,0.0003652598,0.00029347072,0.00042549547],"category_scores_gemma":[0.0050747627,0.000064746586,0.00023146514,0.000116033334,0.0001962271,0.0000502034,0.00001563894,0.0016166396,0.000013892514],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.028920013,0.00332701,0.032688335,0.0011302484,0.006611406,0.00079615484,0.009586992,0.009791146,0.15585051,0.0590798,0.110557936,0.58166045],"study_design_scores_gemma":[0.005395595,0.006803099,0.0014589799,0.000438135,0.0005649769,0.00040621523,0.00031483293,0.00088595256,0.7361381,0.003883497,0.24343714,0.00027343564],"about_ca_topic_score_codex":0.0000043145506,"about_ca_topic_score_gemma":0.0000022392878,"teacher_disagreement_score":0.58138704,"about_ca_system_score_codex":0.000039361537,"about_ca_system_score_gemma":0.00012311776,"threshold_uncertainty_score":0.7023584},"labels":[],"label_agreement":null},{"id":"W2912602935","doi":"10.1038/s41598-018-38452-z","title":"Association of PXR and CAR Polymorphisms and Antituberculosis Drug-Induced Hepatotoxicity","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Specialized Research Fund for the Doctoral Program of Higher Education of China; National Natural Science Foundation of China","keywords":"Pregnane X receptor; Medicine; Pharmacology; Single-nucleotide polymorphism; Ethambutol; Haplotype; Isoniazid; Pyrazinamide; Population; Tuberculosis; Genotype; Genetics; Biology; Gene; Environmental health; Nuclear receptor","score_opus":0.0451432210386106,"score_gpt":0.34443973828777524,"score_spread":0.2992965172491646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2912602935","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885612,0.00018163283,0.0000052324385,0.00039801517,0.0072957445,0.0007282863,0.000014241254,0.00006487862,0.0027507634],"genre_scores_gemma":[0.9957273,0.000058303674,0.000055137178,0.00013292766,0.000072007264,0.00002217915,0.000015700669,0.00001539663,0.0039010507],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99771327,0.00034020797,0.00053069205,0.0006723,0.00037074293,0.00037280653],"domain_scores_gemma":[0.9985425,0.00016706632,0.0005578356,0.0003559241,0.00018367745,0.00019302419],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0035530182,0.00019279994,0.0003485551,0.00022261572,0.00039176404,0.000083760555,0.0000872442,0.00036820615,0.00033480147],"category_scores_gemma":[0.00019219538,0.00019347481,0.00008388568,0.00039454267,0.00016800834,0.00029609507,0.000108714004,0.0004828378,0.000032435208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021041513,0.00008355275,0.38546786,0.00006909158,0.000072858566,0.000019947174,0.00064179004,0.000009745775,0.6101951,0.000113446724,0.0007757253,0.002529836],"study_design_scores_gemma":[0.00057723845,0.00006333744,0.036859296,0.00003874698,0.00012768575,0.0001298836,0.00012294161,0.0008810567,0.9322781,0.0024263575,0.026179302,0.00031607217],"about_ca_topic_score_codex":0.00029566605,"about_ca_topic_score_gemma":0.0001571602,"teacher_disagreement_score":0.34860858,"about_ca_system_score_codex":0.00010884482,"about_ca_system_score_gemma":0.000093980576,"threshold_uncertainty_score":0.78896743},"labels":[],"label_agreement":null},{"id":"W2916230189","doi":"10.3138/canlivj.2018-0022","title":"Alternative medicine products causing acute liver injury: Pandora’s box is open","year":2019,"lang":"en","type":"editorial","venue":"Canadian Liver Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"William Osler Health System; University of British Columbia; University of Manitoba; Western University; Vancouver General Hospital","funders":"","keywords":"Duty; Medicine; Liver failure; Regulatory authority; Public health; Business; Political science; Medical emergency; Public administration; Surgery; Law; Nursing","score_opus":0.13152381353599235,"score_gpt":0.4300985051591729,"score_spread":0.29857469162318057,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2916230189","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0025648717,0.0021206038,0.00004426851,0.0040828506,0.97605485,0.001995474,0.002298028,0.000042045063,0.010797032],"genre_scores_gemma":[0.011885268,0.0088807875,0.00013093407,0.006926742,0.9490734,0.000065034124,0.00038363013,0.00017693863,0.022477318],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.994998,0.001280915,0.000801896,0.0008889299,0.00075389544,0.0012763814],"domain_scores_gemma":[0.99512106,0.00052189926,0.0009485289,0.00048745095,0.0012796756,0.0016414132],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0027118463,0.00075814215,0.0010708908,0.00090205733,0.0014202732,0.00037672895,0.0014871282,0.0024414002,0.0065079923],"category_scores_gemma":[0.00078536524,0.00071975,0.00018985981,0.00046860022,0.00034865804,0.0008171036,0.0002857296,0.009332348,0.0009474999],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042845283,0.000050006543,0.000051131694,0.00012264967,0.0012709913,0.0018847095,0.0029345527,0.000014832317,0.0005239863,0.00005743621,0.98196626,0.010694988],"study_design_scores_gemma":[0.0024067867,0.00047670671,0.000023823904,0.00042229376,0.0009903968,0.00043268857,0.000091051006,0.00024367835,0.0029741642,0.00037331012,0.99077207,0.0007930405],"about_ca_topic_score_codex":0.11224649,"about_ca_topic_score_gemma":0.030505741,"teacher_disagreement_score":0.081740744,"about_ca_system_score_codex":0.0026825045,"about_ca_system_score_gemma":0.007572075,"threshold_uncertainty_score":0.9998797},"labels":[],"label_agreement":null},{"id":"W2916260541","doi":"10.1097/ftd.0000000000000610","title":"Biomarkers of Drug-Induced Liver Toxicity","year":2019,"lang":"en","type":"review","venue":"Therapeutic Drug Monitoring","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Liver toxicity; Toxicity; Pharmacology; Drug; Medicine; Drug toxicity; Internal medicine","score_opus":0.33704016350287,"score_gpt":0.4774862357133376,"score_spread":0.14044607221046757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2916260541","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008761482,0.97350955,0.000018421168,0.000033620032,0.010958435,0.0024921028,0.000085904176,0.00024877567,0.0038917009],"genre_scores_gemma":[0.045759916,0.9506953,0.0000709492,0.00006936174,0.0013229988,0.00024735605,0.000028608942,0.00017030368,0.0016352481],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9942349,0.0021367583,0.0013259792,0.0008822564,0.00047930118,0.0009407764],"domain_scores_gemma":[0.99632055,0.0012704463,0.0011297837,0.0008333404,0.00015683465,0.00028904722],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0021371571,0.0009938125,0.002462749,0.00057057466,0.00034793053,0.000046801175,0.0010132482,0.0013460726,0.0003345008],"category_scores_gemma":[0.000050115043,0.00092673046,0.0010451456,0.00081563747,0.00018474797,0.00023571884,0.0002515126,0.0027735827,0.0007706681],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007150919,0.0002706205,0.00016474324,0.012630052,0.001613002,0.000019390453,0.0008284077,0.0000075798275,0.0016825064,0.00009608098,0.000089761365,0.98252636],"study_design_scores_gemma":[0.0007989212,0.00007753352,0.00004722339,0.004893323,0.0029298384,0.000045050954,0.00017156613,0.000081170874,0.026008114,0.00009696863,0.9637725,0.0010778229],"about_ca_topic_score_codex":0.0001780902,"about_ca_topic_score_gemma":0.00000903396,"teacher_disagreement_score":0.98144853,"about_ca_system_score_codex":0.0005063852,"about_ca_system_score_gemma":0.0004695828,"threshold_uncertainty_score":0.9999504},"labels":[],"label_agreement":null},{"id":"W2921524066","doi":"10.1177/1740774519836766","title":"Determination of fasiglifam-induced liver toxicity: Insights from the data monitoring committee of the fasiglifam clinical trials program","year":2019,"lang":"en","type":"article","venue":"Clinical Trials","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Medicine; Adverse effect; Alanine transaminase; Liver injury; Toxicity; Aspartate transaminase; Internal medicine; Transaminase; Pharmacology; Drug; Liver function tests; Clinical trial; Biology","score_opus":0.7970184672520017,"score_gpt":0.6334126584100205,"score_spread":0.16360580884198117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921524066","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97605795,0.00046171263,0.00018420209,0.00090544845,0.015496242,0.005741922,0.0004043304,0.00009016037,0.0006580085],"genre_scores_gemma":[0.9936008,0.000871299,0.00064144103,0.00073570904,0.0038202996,0.00012366037,0.00005644089,0.000036775546,0.00011357353],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.93664867,0.05461213,0.006800426,0.0009046688,0.0006148952,0.00041918864],"domain_scores_gemma":[0.9014869,0.09123317,0.004579475,0.0021016656,0.00035853824,0.00024025673],"candidate_categories":["metaresearch","research_integrity"],"consensus_categories":["metaresearch","research_integrity"],"category_scores_codex":[0.07603125,0.0003804998,0.0026897693,0.00007888504,0.00030761835,0.00005477206,0.002240906,0.0017001078,0.0003340075],"category_scores_gemma":[0.065622866,0.00022370557,0.001252384,0.00045419182,0.00058259274,0.0003104265,0.00085703685,0.002799491,0.00012913332],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021612411,0.0023470211,0.123604104,0.00009448377,0.00092566136,0.0000048749102,0.0005012098,0.000013392912,0.05061636,0.00025859682,0.0010858356,0.8183872],"study_design_scores_gemma":[0.026680276,0.0032895957,0.2261922,0.0008808278,0.0047172145,0.000008068584,0.000991963,0.016830098,0.57497066,0.007337099,0.13684493,0.0012570622],"about_ca_topic_score_codex":0.00013487371,"about_ca_topic_score_gemma":0.00006483235,"teacher_disagreement_score":0.81713015,"about_ca_system_score_codex":0.00004591519,"about_ca_system_score_gemma":0.0003540051,"threshold_uncertainty_score":0.9995959},"labels":[],"label_agreement":null},{"id":"W2921994914","doi":"10.1093/jcag/gwz006.059","title":"A60 PATIENT KNOWLEDGE-GAPS IN HEPATOTOXIC EFFECTS OF ACETAMINOPHEN FORMULATIONS","year":2019,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Acetaminophen; Medicine; Exact test; Analgesic; Incidence (geometry); Medical prescription; Cohort; Accidental; Internal medicine; Anesthesia; Pharmacology","score_opus":0.022691179197961292,"score_gpt":0.3156693932816883,"score_spread":0.29297821408372704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921994914","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99462956,0.000051471583,0.000012001465,0.0015350122,0.002497832,0.00046746,0.00002875129,0.0000030361934,0.00077487394],"genre_scores_gemma":[0.998955,0.000028170347,0.0000494136,0.0006170847,0.00007347477,0.000007755737,0.0000022160484,0.000010492039,0.00025635696],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9974738,0.0011558974,0.00072510866,0.00010226874,0.00018786633,0.00035507756],"domain_scores_gemma":[0.9976115,0.00037260837,0.0014005501,0.00013674359,0.000315547,0.0001630524],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012359703,0.00012327298,0.0004226275,0.00043565748,0.000088984525,0.0000055768123,0.00028067967,0.00035633263,0.00010667452],"category_scores_gemma":[0.00041782766,0.000107484666,0.00021351116,0.00024014618,0.000051005773,0.00012289955,0.000039690152,0.00083566573,0.000015545435],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023924703,0.0001987615,0.97823155,0.000087983106,0.00020647267,0.0000042960373,0.0012475722,0.0013131024,0.01655492,0.0001760342,0.00072653743,0.0010135302],"study_design_scores_gemma":[0.0066251983,0.0020636676,0.9273245,0.00020710022,0.00022777662,0.000058082267,0.00012171676,0.0014725275,0.046923224,0.0011635906,0.01364858,0.00016406964],"about_ca_topic_score_codex":0.0015007745,"about_ca_topic_score_gemma":0.120746315,"teacher_disagreement_score":0.11924554,"about_ca_system_score_codex":0.0012350061,"about_ca_system_score_gemma":0.00038175183,"threshold_uncertainty_score":0.89529777},"labels":[],"label_agreement":null},{"id":"W2922328150","doi":"10.1093/jcag/gwz006.061","title":"A62 LIVER CLEANSE, A SOLUTION OR PROBLEM? A CASE REPORT","year":2019,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Medicine; Jaundice; Liver injury; Hepatitis; Fulminant hepatitis; Fulminant hepatic failure; Liver function tests; Liver function; Cirrhosis; Liver biopsy; Natural history; Gastroenterology; Internal medicine; Liver transplantation; Biopsy; Transplantation","score_opus":0.05760044638683408,"score_gpt":0.3409925725168719,"score_spread":0.2833921261300378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922328150","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9874247,0.00001146867,0.000053350974,0.008547137,0.00244696,0.0003933477,0.00003766876,0.0000069577686,0.001078408],"genre_scores_gemma":[0.99460846,0.000019104787,0.00016596021,0.0024540562,0.00021355874,0.0000055906225,0.0000023994855,0.000011845712,0.0025190036],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975355,0.0010653548,0.0006667931,0.0001252285,0.00021190837,0.00039518517],"domain_scores_gemma":[0.9973146,0.00015008468,0.0017191679,0.00014622984,0.00043875934,0.00023121292],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0027397645,0.000121214274,0.0003207465,0.00024182173,0.00022326266,0.000013905549,0.0002259157,0.0005325891,0.00047503132],"category_scores_gemma":[0.0003640305,0.00009334597,0.000205939,0.00016562398,0.000058666694,0.00015127366,0.000033098,0.0013516168,0.000030105508],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020531362,0.00023165687,0.9604107,0.000087982095,0.00080822356,0.005629032,0.0013113416,0.0010758128,0.005996993,0.00014887405,0.020314064,0.0019321449],"study_design_scores_gemma":[0.019476965,0.007342022,0.24764673,0.00029692907,0.0016639414,0.3021871,0.0007639695,0.0055812043,0.00957911,0.0013513832,0.40339294,0.0007177238],"about_ca_topic_score_codex":0.006586589,"about_ca_topic_score_gemma":0.40346307,"teacher_disagreement_score":0.712764,"about_ca_system_score_codex":0.0013201198,"about_ca_system_score_gemma":0.00061084947,"threshold_uncertainty_score":0.9956996},"labels":[],"label_agreement":null},{"id":"W2924380794","doi":"10.1016/j.aprim.2018.09.011","title":"Programa para la adecuación del uso de paracetamol a dosis menores y más seguras: implantación y resultados","year":2019,"lang":"es","type":"letter","venue":"Atención Primaria","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Physics; Humanities; Art","score_opus":0.09503477634240295,"score_gpt":0.4120264965037777,"score_spread":0.3169917201613748,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2924380794","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7986131,0.005389094,0.0008223998,0.13930625,0.012799435,0.01576604,0.0043093297,0.0018130011,0.02118137],"genre_scores_gemma":[0.78856885,0.008252503,0.0024567917,0.17772949,0.007766141,0.0032674372,0.0029915695,0.0006827251,0.008284469],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9843965,0.0062675676,0.0021675846,0.00259715,0.0011129833,0.0034581951],"domain_scores_gemma":[0.9919874,0.0033305725,0.00174893,0.0016476882,0.0005484864,0.0007369435],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"category_scores_codex":[0.004452155,0.0022858412,0.002377613,0.0008126128,0.0013945193,0.0006539744,0.0020810058,0.00896492,0.0015795969],"category_scores_gemma":[0.00058912183,0.0023010694,0.0010604378,0.0011179015,0.0009214908,0.00074673444,0.00074612524,0.012613417,0.004148534],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007923703,0.0036194732,0.10632892,0.009621571,0.009938591,0.0052821767,0.0072320746,0.0005402733,0.15610948,0.0029888356,0.5474154,0.14299953],"study_design_scores_gemma":[0.005597588,0.0008444375,0.01248448,0.0005764805,0.002824213,0.0014651327,0.00015663375,0.002159967,0.037442427,0.0014794262,0.93204963,0.0029195603],"about_ca_topic_score_codex":0.0029846975,"about_ca_topic_score_gemma":0.000078851466,"teacher_disagreement_score":0.3846343,"about_ca_system_score_codex":0.001314114,"about_ca_system_score_gemma":0.0019151401,"threshold_uncertainty_score":0.9999055},"labels":[],"label_agreement":null},{"id":"W2928463868","doi":"10.1097/md.0000000000014992","title":"Herb induced liver injury after using herbal medicine","year":2019,"lang":"en","type":"review","venue":"Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Epidemiology; Traditional medicine; Herb; Demography; Family medicine; Internal medicine; Medicinal herbs","score_opus":0.48417003797723207,"score_gpt":0.5421239383411008,"score_spread":0.05795390036386877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2928463868","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012244376,0.9798587,0.00004466565,0.0005296087,0.010367244,0.0024315068,0.000058911115,0.00017534837,0.005309568],"genre_scores_gemma":[0.0025654687,0.98552495,0.000037483373,0.0027339186,0.006431639,0.00025590035,0.000118387135,0.00014978267,0.00218245],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99457866,0.0017199754,0.00140943,0.00091916695,0.0005301496,0.0008426005],"domain_scores_gemma":[0.997258,0.0006529136,0.0007845397,0.0006830827,0.00015702653,0.00046445418],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0022644566,0.001010323,0.0031655303,0.0006891407,0.00026396042,0.00001209513,0.00057624996,0.002393707,0.00968106],"category_scores_gemma":[0.00031934617,0.0007321477,0.0003805145,0.00093451515,0.0005105755,0.00015970402,0.00020443177,0.004219296,0.0013742745],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016729247,0.000113287104,0.00002375706,0.015016375,0.00048139176,0.00021971772,0.0007055349,0.000001275955,0.00042710773,0.00006898151,0.005180781,0.9775945],"study_design_scores_gemma":[0.0010279611,0.00055159227,0.000008828886,0.013323012,0.003519777,0.0002456359,0.00005139278,0.0001467469,0.0000776099,0.00006211236,0.98031163,0.0006737014],"about_ca_topic_score_codex":0.00037860358,"about_ca_topic_score_gemma":0.000028413395,"teacher_disagreement_score":0.9769208,"about_ca_system_score_codex":0.00053279946,"about_ca_system_score_gemma":0.0003960282,"threshold_uncertainty_score":0.999513},"labels":[],"label_agreement":null},{"id":"W2928712866","doi":"10.1139/bcb-2018-0212","title":"Biological activity of <i>Echinops spinosus</i> on inhibition of paracetamol-induced renal inflammation","year":2019,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Cairo University","keywords":"Pharmacology; Nephrotoxicity; Kidney; Oxidative stress; Creatinine; Lipid peroxidation; Glutathione; Nitric oxide; Inflammation; Chemistry; Blood urea nitrogen; Nitric oxide synthase; Acetaminophen; Biochemistry; Medicine; Endocrinology; Internal medicine; Enzyme","score_opus":0.06783318070855292,"score_gpt":0.35173153028234955,"score_spread":0.2838983495737966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2928712866","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99115723,0.00007889999,0.000025637655,0.00012423663,0.00028096183,0.00032107966,0.00005734344,0.000028709235,0.007925921],"genre_scores_gemma":[0.9993904,0.00012884263,0.000031009527,0.000113887196,0.00012335432,0.000017346214,0.00006465296,0.00000631664,0.00012417727],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987563,0.00033683426,0.00030973784,0.00032105178,0.000061715924,0.00021439472],"domain_scores_gemma":[0.99917185,0.00019029307,0.0003312714,0.0001688868,0.000059480528,0.000078239806],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050654134,0.00017877635,0.0003053113,0.000057087578,0.00007283941,0.0000032112102,0.000089352376,0.0008630174,0.00019595271],"category_scores_gemma":[0.00004831537,0.00015784532,0.000082236,0.000118380645,0.00017601377,0.00004421113,0.0000558824,0.0005231813,0.000024675162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007015302,0.0002046562,0.005257794,0.00016986177,0.000029672983,0.0000013169996,0.00006373577,0.000017536246,0.98012954,0.0003787454,0.000020986387,0.013024643],"study_design_scores_gemma":[0.0010263275,0.0006116089,0.0016202601,0.000024901723,0.000021676693,0.0000059637546,0.000025844583,0.0001506086,0.9937927,0.00040612245,0.002155157,0.00015881319],"about_ca_topic_score_codex":0.000022526272,"about_ca_topic_score_gemma":0.0000011682047,"teacher_disagreement_score":0.013663194,"about_ca_system_score_codex":0.00002567909,"about_ca_system_score_gemma":0.00004421079,"threshold_uncertainty_score":0.6656381},"labels":[],"label_agreement":null},{"id":"W2937806011","doi":"10.1016/j.cmpb.2019.04.012","title":"Predicting daily outcomes in acetaminophen-induced acute liver failure patients with machine learning techniques","year":2019,"lang":"en","type":"article","venue":"Computer Methods and Programs in Biomedicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Acetaminophen; Liver failure; Computer science; Medicine; Intensive care medicine; Machine learning; Artificial intelligence; Internal medicine; Anesthesia","score_opus":0.07980940378037887,"score_gpt":0.4113598202379246,"score_spread":0.33155041645754574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2937806011","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99114937,0.00018918375,0.0055653867,0.00038871955,0.0006597667,0.0017105916,0.0000066141265,0.00018488121,0.00014548001],"genre_scores_gemma":[0.87009007,0.00010764709,0.12881656,0.0005262442,0.00014386332,0.00012583172,0.00006761034,0.000033117907,0.00008903473],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9971247,0.0011704208,0.00047877454,0.00053840346,0.00019234249,0.0004953721],"domain_scores_gemma":[0.9989753,0.00039796796,0.00020234393,0.00019383733,0.00007546322,0.00015512148],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0021879252,0.00033959444,0.00061115745,0.00041880875,0.00012983421,0.000036391757,0.00020833702,0.00044596312,0.00005255248],"category_scores_gemma":[0.000035616944,0.00025414853,0.000049782477,0.00062201347,0.00013800878,0.0002010771,0.00018242792,0.0016211893,0.0000066596212],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013948935,0.00022311648,0.55288523,0.000079155754,0.00007366052,0.00001943648,0.0009711326,0.000004239088,0.0035035117,0.000016040378,0.0000026989665,0.44208232],"study_design_scores_gemma":[0.019184062,0.009086102,0.8200446,0.00096777076,0.0003351115,0.00009745373,0.00040084537,0.067858905,0.023847546,0.00045893682,0.056149524,0.0015691584],"about_ca_topic_score_codex":0.00020327936,"about_ca_topic_score_gemma":0.00008719039,"teacher_disagreement_score":0.44051316,"about_ca_system_score_codex":0.00007726144,"about_ca_system_score_gemma":0.00002682299,"threshold_uncertainty_score":0.99999106},"labels":[],"label_agreement":null},{"id":"W2939249740","doi":"10.1016/j.freeradbiomed.2019.04.012","title":"Circulating Peroxiredoxin-1 is a novel damage-associated molecular pattern and aggravates acute liver injury via promoting inflammation","year":2019,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":76,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; St. Joseph's Hospital; McMaster University","funders":"Xiangya Hospital, Central South University; Natural Science Foundation of Hunan Province; National Natural Science Foundation of China","keywords":"Inflammation; Inflammasome; Medicine; Immunology; Pyrin domain; Peroxiredoxin; Tumor necrosis factor alpha; Liver injury; Pharmacology; Chemistry; Biochemistry","score_opus":0.044486641053510405,"score_gpt":0.3730940503124363,"score_spread":0.3286074092589259,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2939249740","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992398,0.0005882959,0.0011531911,0.004193598,0.000526946,0.0006373707,0.000053779117,0.00008969211,0.00035910486],"genre_scores_gemma":[0.99655664,0.00036530857,0.000098463286,0.0025049306,0.00025361066,0.00003181762,0.00009404496,0.000018192806,0.000077020566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99827915,0.00038348176,0.00039028886,0.00043472872,0.00011156466,0.00040080142],"domain_scores_gemma":[0.9989542,0.00035756076,0.00022352148,0.00017389683,0.000066742345,0.00022409341],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010070037,0.00024691192,0.0004056786,0.00013362264,0.00028434588,0.000009840699,0.00014805948,0.00076274714,0.00040458865],"category_scores_gemma":[0.00042011825,0.00020868532,0.000044727574,0.00017182984,0.0005099567,0.00010636207,0.00013320097,0.0009423535,0.000023894285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000080391226,0.00006665848,0.030797284,0.00010273309,0.0002580051,0.000027005806,0.0018270425,0.0000010941668,0.90037954,0.00038621336,0.00009869426,0.06597533],"study_design_scores_gemma":[0.023151236,0.0048467387,0.07355434,0.0011260152,0.0016720855,0.00082660204,0.00045438032,0.112070076,0.74687797,0.013265109,0.020176604,0.0019788751],"about_ca_topic_score_codex":0.0001626846,"about_ca_topic_score_gemma":0.00002502067,"teacher_disagreement_score":0.1535016,"about_ca_system_score_codex":0.000043481585,"about_ca_system_score_gemma":0.00003457644,"threshold_uncertainty_score":0.85099405},"labels":[],"label_agreement":null},{"id":"W2939747625","doi":"10.1139/apnm-2018-0246","title":"Protective effect of essential oil of <i>Cinnamomum verum</i> bark on hepatic and renal toxicity induced by carbon tetrachloride in rats","year":2019,"lang":"en","type":"article","venue":"Applied Physiology Nutrition and Metabolism","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Carbon tetrachloride; Oxidative stress; Toxicity; Creatinine; Aspartate transaminase; Pharmacology; Lactate dehydrogenase; Alanine transaminase; Alkaline phosphatase; Kidney; Bilirubin; Cinnamomum; Schisandra chinensis; Thiobarbituric acid; TBARS; Biochemistry; Internal medicine; Lipid peroxidation; Medicine; Enzyme; Pathology","score_opus":0.0191393262237424,"score_gpt":0.31463458065103866,"score_spread":0.29549525442729624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2939747625","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970438,0.00038504374,0.0000040223226,0.00008079689,0.00042669105,0.0011650907,0.000058835518,0.00002691857,0.0008088387],"genre_scores_gemma":[0.9987533,0.00045464328,0.000013517583,0.00024516828,0.000114206436,0.00035017074,0.000031830965,0.000018339833,0.000018802491],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979926,0.0006968826,0.00042537556,0.00044566786,0.00013237154,0.00030715278],"domain_scores_gemma":[0.9989973,0.0004241663,0.00026391505,0.0001646262,0.000048281407,0.000101724516],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00066370715,0.00027843117,0.00073566363,0.00021227215,0.00008033438,0.000004818124,0.00010096849,0.0005680819,0.00003809464],"category_scores_gemma":[0.00004031361,0.00026007098,0.00006924578,0.00026922202,0.00021136385,0.00006870299,0.000054991808,0.0009045262,0.0000059918316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024304094,0.00048172532,0.00019691061,0.000494706,0.00008795028,8.6497755e-7,0.00030900096,0.000022923343,0.9887489,0.0008301268,0.000019772722,0.006376685],"study_design_scores_gemma":[0.006787466,0.00023057923,0.008899738,0.00006843617,0.000096427284,0.0000028732175,0.000051998733,0.00035799088,0.98090804,0.0013619484,0.0010139503,0.00022054798],"about_ca_topic_score_codex":0.00013199303,"about_ca_topic_score_gemma":0.000017670136,"teacher_disagreement_score":0.008702828,"about_ca_system_score_codex":0.000027269238,"about_ca_system_score_gemma":0.00002920904,"threshold_uncertainty_score":0.99998516},"labels":[],"label_agreement":null},{"id":"W2943396929","doi":"10.26452/ijrps.v10i2.411","title":"Evaluation of the hepatotoxicity of the anti-diabetic drug Diarid: An ayurvedic formulation in white swiss albino mice","year":2019,"lang":"en","type":"article","venue":"International Journal of Research in Pharmaceutical Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"MacEwan University","funders":"","keywords":"Toxicity; Medicine; Drug; Pharmacology; Acute toxicity; Median lethal dose; Lethal dose; Gastrointestinal tract; Pathological; Physiology; Toxicology; Internal medicine; Biology","score_opus":0.339644027408445,"score_gpt":0.5610807846272164,"score_spread":0.22143675721877143,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943396929","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99000806,0.00022869515,0.000009852365,0.005294084,0.0023609446,0.0007819457,0.000014253499,0.0000033747294,0.0012988037],"genre_scores_gemma":[0.9994448,0.00012710055,0.000031709176,0.00021128757,0.00014015252,0.00001331214,7.6989636e-7,0.000005966656,0.000024926387],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9903127,0.0049390756,0.00081250083,0.00022992869,0.0033223303,0.0003834658],"domain_scores_gemma":[0.9968172,0.0010262992,0.00046787827,0.00015083906,0.0014168111,0.00012100365],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.033067375,0.000118672055,0.00023738002,0.0005701468,0.00015424595,0.000039103114,0.0015891945,0.00015953871,0.0003546512],"category_scores_gemma":[0.0011130696,0.000075353186,0.0001365969,0.0013689443,0.00075729896,0.0006354443,0.0002484116,0.00170171,0.0000069557627],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020420291,0.00062053074,0.83766425,0.000040783638,0.00005446557,0.0000033835547,0.0010641112,0.023795526,0.120625205,0.0008781401,0.000039606843,0.015009826],"study_design_scores_gemma":[0.002738791,0.00015246861,0.36346233,0.00032379653,0.00004583542,0.00003232715,0.00046792888,0.19635049,0.42371655,0.011723041,0.00086141104,0.0001250291],"about_ca_topic_score_codex":0.00018580726,"about_ca_topic_score_gemma":0.0002655556,"teacher_disagreement_score":0.4742019,"about_ca_system_score_codex":0.0004173161,"about_ca_system_score_gemma":0.0007917852,"threshold_uncertainty_score":0.9956606},"labels":[],"label_agreement":null},{"id":"W2950470074","doi":"10.3389/fphar.2019.00782","title":"The Essential Oils and Eucalyptol From Artemisia vulgaris L. Prevent Acetaminophen-Induced Liver Injury by Activating Nrf2–Keap1 and Enhancing APAP Clearance Through Non-Toxic Metabolic Pathway","year":2019,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Eucalyptol; Chemistry; Acetaminophen; Liver injury; CYP2E1; Pharmacology; Malondialdehyde; Superoxide dismutase; Biochemistry; Metabolism; Oxidative stress; Food science; Medicine; Cytochrome P450; Essential oil","score_opus":0.02297459635672089,"score_gpt":0.3358945706060813,"score_spread":0.3129199742493604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950470074","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9806742,0.0072315624,0.0014415986,0.00057113,0.0074831164,0.0017419127,0.000080847014,0.00008668282,0.0006889354],"genre_scores_gemma":[0.9904858,0.00568654,0.0007027759,0.0017088751,0.0005691898,0.0003258864,0.000018245606,0.00006252002,0.0004401753],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99550515,0.0015422165,0.0007716225,0.0009465552,0.00025371212,0.0009807581],"domain_scores_gemma":[0.9982017,0.0007274367,0.00045525806,0.0002912101,0.0000707939,0.00025360237],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0011873649,0.00053000276,0.0008119174,0.00015078255,0.0007452966,0.00008061767,0.0004051426,0.00083931006,0.00029049846],"category_scores_gemma":[0.00008726429,0.0004894582,0.000115285686,0.00035981066,0.00037085108,0.00055192475,0.0002895241,0.002388268,0.000056504374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001029715,0.00025942744,0.0052707405,0.00008708382,0.00040842153,0.000025049758,0.00296174,0.000029964442,0.9016373,0.00006690597,0.004500001,0.083723664],"study_design_scores_gemma":[0.003207073,0.00017540621,0.0026694466,0.00004404633,0.00018499212,0.000019365085,0.000552059,0.006899336,0.92067397,0.00072585355,0.06430641,0.00054202735],"about_ca_topic_score_codex":0.00022097597,"about_ca_topic_score_gemma":0.00004478432,"teacher_disagreement_score":0.083181635,"about_ca_system_score_codex":0.00017159543,"about_ca_system_score_gemma":0.00014475439,"threshold_uncertainty_score":0.9999133},"labels":[],"label_agreement":null},{"id":"W2962821953","doi":"10.1053/j.gastro.2019.03.076","title":"Genome-Wide Association Studies of Drug-Induced Liver Injury Make Progress Beyond the HLA Region","year":2019,"lang":"en","type":"letter","venue":"Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Pharmacogenomics; Genome-wide association study; PTPN22; Odds ratio; Medicine; Liver injury; Genetic association; Bioinformatics; Genetics; Biology; Internal medicine; Gene; Pharmacology; Genotype; Single-nucleotide polymorphism","score_opus":0.09844960576493014,"score_gpt":0.3759174226234329,"score_spread":0.27746781685850275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2962821953","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.57363194,0.00068215345,0.000016115397,0.4165974,0.006538709,0.001850702,0.00015187246,0.00010313033,0.00042796382],"genre_scores_gemma":[0.40098155,0.0010833573,0.000034849087,0.5889827,0.0036788932,0.00048971665,0.00025837345,0.000099654586,0.0043909336],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9930397,0.003642338,0.0009476931,0.0007606443,0.00044513837,0.0011644312],"domain_scores_gemma":[0.995177,0.0019467336,0.001708271,0.0006283551,0.0004663157,0.00007335541],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0017930218,0.00063973037,0.0011266159,0.00035150914,0.00037493327,0.000027471171,0.0007923026,0.0022799133,0.00012129602],"category_scores_gemma":[0.0004115817,0.00053035235,0.0004123496,0.00022178706,0.00045864904,0.00011592232,0.00036467062,0.0061290744,0.00022848368],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009534137,0.00020640124,0.14833376,0.0006574224,0.0023500859,0.00019409748,0.0019047046,0.000021315847,0.0014418181,0.000012674423,0.8414928,0.0024315305],"study_design_scores_gemma":[0.0018548516,0.0011394138,0.016086591,0.000076875156,0.0009697645,0.00009456845,0.00018623962,0.000055381523,0.0031687438,0.00043819184,0.9754844,0.0004450355],"about_ca_topic_score_codex":0.000032530195,"about_ca_topic_score_gemma":0.00010119672,"teacher_disagreement_score":0.17265043,"about_ca_system_score_codex":0.00059876713,"about_ca_system_score_gemma":0.00011010317,"threshold_uncertainty_score":0.9997148},"labels":[],"label_agreement":null},{"id":"W2963314567","doi":"10.1016/j.ebiom.2019.07.054","title":"Emerging novel therapies against paracetamol (acetaminophen) hepatotoxicity","year":2019,"lang":"en","type":"letter","venue":"EBioMedicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Acetaminophen; Medicine; Acetylcysteine; Liver injury; Pharmacology; Antidote; acetaminophen overdose; Analgesic; Internal medicine; Toxicity; Chemistry; Antioxidant","score_opus":0.1237846205411338,"score_gpt":0.4025144070650046,"score_spread":0.27872978652387076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2963314567","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10799045,0.003467549,0.0013100953,0.8318196,0.025635187,0.0044312123,0.00083824794,0.0010336334,0.023474049],"genre_scores_gemma":[0.095100425,0.001070814,0.00022969725,0.8625007,0.017314188,0.00033376983,0.0015177805,0.00024343454,0.021689143],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9944513,0.0008376069,0.001103759,0.0012590707,0.00084801996,0.0015002791],"domain_scores_gemma":[0.99687934,0.0008863425,0.0008054983,0.00095206633,0.00022752244,0.0002492543],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0016952741,0.0011521353,0.001488419,0.00078495353,0.00059338263,0.0000616157,0.0009307306,0.004017138,0.0023364516],"category_scores_gemma":[0.00018599372,0.0010438333,0.00045731713,0.0007573491,0.0005930946,0.00026355212,0.00022740164,0.010087422,0.0019743338],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016654792,0.0003078919,0.00082559243,0.0009045151,0.001033849,0.0004588788,0.0014133794,0.000051686002,0.094004706,0.000041212643,0.8730595,0.02773225],"study_design_scores_gemma":[0.003041294,0.000265928,0.0002183096,0.000266836,0.00036243923,0.00009670494,0.00011028414,0.0015147034,0.012460268,0.00013246357,0.9804484,0.0010823648],"about_ca_topic_score_codex":0.0001230056,"about_ca_topic_score_gemma":0.000012608543,"teacher_disagreement_score":0.10738891,"about_ca_system_score_codex":0.00042220624,"about_ca_system_score_gemma":0.00026716772,"threshold_uncertainty_score":0.9992012},"labels":[],"label_agreement":null},{"id":"W2963506905","doi":"10.1016/j.eclinm.2019.07.009","title":"Improving the management of the paracetamol poisoned patient","year":2019,"lang":"en","type":"article","venue":"EClinicalMedicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Medicine; Acetylcysteine; Adverse effect; Regimen; Acetaminophen; Randomized controlled trial; Anesthesia; Pediatrics; Internal medicine","score_opus":0.10408378335806506,"score_gpt":0.42296369654547844,"score_spread":0.3188799131874134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2963506905","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9801554,0.00021906587,0.00006987745,0.004593341,0.0036833682,0.0013883483,0.0000074714176,0.000037382895,0.009845757],"genre_scores_gemma":[0.99378794,0.0001031558,0.00010580263,0.0042666714,0.0001947692,0.00005628539,0.0000026430628,0.000012559092,0.0014701786],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99821264,0.00047289245,0.0005524532,0.00024174545,0.00025723153,0.0002630478],"domain_scores_gemma":[0.99851143,0.0005288889,0.00033757402,0.0004904488,0.00005376933,0.00007788748],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014843786,0.00014122228,0.0002452064,0.000027304099,0.0002012299,0.0000050734375,0.00039013664,0.00020549133,0.00089359],"category_scores_gemma":[0.00009140518,0.000073988456,0.00014451008,0.00024358263,0.00022113694,0.000043010634,0.00020145961,0.000967969,0.00023460829],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001480989,0.0013770575,0.111706406,0.0008731163,0.0013376129,0.000035067464,0.0031493339,0.0009749443,0.06847687,0.010937362,0.0050095725,0.7946417],"study_design_scores_gemma":[0.0163422,0.0030495443,0.19952919,0.0007924533,0.0017451473,0.00008037303,0.004164443,0.014501154,0.17997772,0.005001143,0.57384676,0.0009698944],"about_ca_topic_score_codex":0.00003590441,"about_ca_topic_score_gemma":0.0000045654533,"teacher_disagreement_score":0.7936718,"about_ca_system_score_codex":0.000033922894,"about_ca_system_score_gemma":0.000032971493,"threshold_uncertainty_score":0.9784184},"labels":[],"label_agreement":null},{"id":"W2965449651","doi":"10.3389/fphar.2019.00837","title":"Mechanistic Studies of Idiosyncratic DILI: Clinical Implications","year":2019,"lang":"en","type":"review","venue":"Frontiers in Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":101,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Innate immune system; Acquired immune system; Biology; Liver injury; Pattern recognition receptor; Mechanism (biology); Immunology; Human leukocyte antigen; Antigen; Pharmacology","score_opus":0.5739006275705014,"score_gpt":0.6116953061298952,"score_spread":0.03779467855939378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2965449651","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00018888967,0.96350783,0.0007254834,0.00021536041,0.03027222,0.0036622845,0.0002705859,0.00009447664,0.0010628793],"genre_scores_gemma":[0.0009162028,0.9948481,0.000872416,0.00060349575,0.00075052667,0.0010975042,0.00009809699,0.000092112736,0.00072154886],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.990689,0.004745478,0.0025933601,0.0009848739,0.00017947533,0.00080783706],"domain_scores_gemma":[0.99529594,0.0023206165,0.0014308258,0.00051029073,0.00020237871,0.00023995269],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.003061045,0.00073999516,0.004427647,0.00086884823,0.00020160149,0.000009889289,0.00093790714,0.0021334959,0.00033078348],"category_scores_gemma":[0.0004581749,0.00070174865,0.00086636253,0.0009967192,0.0006837485,0.00012624115,0.00031639202,0.0036821177,0.0002858849],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013003164,0.0006952527,0.00041779413,0.018157229,0.002892985,0.000037056976,0.00017438094,0.000033605575,0.000110826906,0.0010480011,0.04446333,0.9318395],"study_design_scores_gemma":[0.00141439,0.0002665084,0.000013699023,0.001034189,0.0049416386,0.000047965717,0.00007514236,0.0002930898,0.00016490788,0.003259847,0.98788875,0.0005998837],"about_ca_topic_score_codex":0.000007407562,"about_ca_topic_score_gemma":0.000007675208,"teacher_disagreement_score":0.9434254,"about_ca_system_score_codex":0.00054986373,"about_ca_system_score_gemma":0.0008004083,"threshold_uncertainty_score":0.99954337},"labels":[],"label_agreement":null},{"id":"W2972906095","doi":"10.1039/c9tx00158a","title":"Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use” by D. N. Bateman and J. W. Dear, Toxicol. Res., 2019, 8, 489","year":2019,"lang":"en","type":"article","venue":"Toxicology Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Hospital for Sick Children; Queen's University; Alberta Health Services","funders":"","keywords":"Acetylcysteine; Protocol (science); Perspective (graphical); Medicine; Chemistry; Computer science; Artificial intelligence; Alternative medicine; Pathology; Biochemistry","score_opus":0.19002010937832672,"score_gpt":0.4888190172217171,"score_spread":0.29879890784339036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972906095","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.986478,0.00068110146,0.000005935225,0.0060360976,0.00034868202,0.002179934,0.000106357074,0.000031316617,0.0041325996],"genre_scores_gemma":[0.99611306,0.0005202832,0.00009170039,0.00095897727,0.00005003231,0.00014804844,0.000015910846,0.000036379955,0.0020656073],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99418646,0.0031840056,0.00065129885,0.00064576644,0.0004861766,0.00084627466],"domain_scores_gemma":[0.9959944,0.0027262014,0.00024773827,0.00044803123,0.00034334502,0.00024028968],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.004552496,0.00025765516,0.0007111373,0.0007593324,0.0001565747,0.000021215814,0.00040880495,0.00088956987,0.0006537533],"category_scores_gemma":[0.0007590505,0.00027575475,0.00009793223,0.00076349376,0.0007109885,0.0001882854,0.0002963246,0.0024962244,0.000164451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0055208085,0.0032743674,0.09006444,0.00036981594,0.000405154,0.000070976144,0.0052633085,0.00041049844,0.8441781,0.019490244,0.025617782,0.0053345202],"study_design_scores_gemma":[0.014985244,0.010223599,0.077843785,0.00038934936,0.000096365955,0.00006386178,0.003970102,0.0029995977,0.7467762,0.0036983015,0.1380353,0.00091826584],"about_ca_topic_score_codex":0.0008678295,"about_ca_topic_score_gemma":0.00023099696,"teacher_disagreement_score":0.11241751,"about_ca_system_score_codex":0.00038805834,"about_ca_system_score_gemma":0.00019788409,"threshold_uncertainty_score":0.9999695},"labels":[],"label_agreement":null},{"id":"W2978800811","doi":"10.14740/gr1212","title":"Acute Liver Injury in a Patient Treated With Rosuvastatin: A Rare Adverse Effect","year":2019,"lang":"en","type":"article","venue":"Gastroenterology Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Rosuvastatin; Liver injury; Autoimmune hepatitis; Incidence (geometry); Internal medicine; Population; Hepatitis; Gastroenterology; Liver biopsy; Asymptomatic; Adverse effect; Drug; Biopsy; Pharmacology","score_opus":0.07475535363537586,"score_gpt":0.42458835755261815,"score_spread":0.34983300391724226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2978800811","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99608576,0.000024408238,0.000014819294,0.00029829366,0.00027126903,0.0020640644,0.0000619213,0.00011552072,0.0010639534],"genre_scores_gemma":[0.99819684,0.000056166038,0.0000627796,0.00064852805,0.00005622502,0.00051711174,0.00003576632,0.000046226498,0.0003803572],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99387676,0.0036611157,0.00033056317,0.00059207395,0.0003450545,0.0011944593],"domain_scores_gemma":[0.9988212,0.0003566789,0.0000962211,0.00032121668,0.00016444898,0.00024025224],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0016888505,0.00027302638,0.00041844838,0.00058975833,0.00017440727,0.000016684333,0.00029145743,0.0004205872,0.000765628],"category_scores_gemma":[0.00005345241,0.00022819506,0.00008525782,0.00053777744,0.00032597338,0.00018550378,0.00019561093,0.002665358,0.000703463],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.023418015,0.00047433074,0.92769134,0.00009212978,0.0002489542,0.0008887553,0.0009950851,0.00020045153,0.036018442,0.000023652556,0.0007438812,0.00920495],"study_design_scores_gemma":[0.04289095,0.06648607,0.59294623,0.0004502237,0.00035097267,0.0018867762,0.0011071262,0.012964411,0.25058967,0.00019137382,0.028859403,0.0012768029],"about_ca_topic_score_codex":0.00017522533,"about_ca_topic_score_gemma":0.00027882084,"teacher_disagreement_score":0.33474514,"about_ca_system_score_codex":0.00023695176,"about_ca_system_score_gemma":0.000082192106,"threshold_uncertainty_score":0.9996355},"labels":[],"label_agreement":null},{"id":"W2979536741","doi":"10.5114/pg.2019.88173","title":"Chondroitin sulphate: unmasking auto-immune hepatitis","year":2019,"lang":"en","type":"article","venue":"Gastroenterology Review","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Immune system; Medicine; Virology; Internal medicine; Immunology","score_opus":0.06449414430037441,"score_gpt":0.38808266768243077,"score_spread":0.32358852338205635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2979536741","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9580128,0.022895856,0.00033623842,0.0053697797,0.0044357395,0.0022142972,0.000054380776,0.00031611795,0.0063647497],"genre_scores_gemma":[0.92364013,0.050886467,0.00020561893,0.022657102,0.0002459439,0.0002573382,0.00009401232,0.000048449623,0.0019649065],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.99650854,0.001241123,0.00073390413,0.0005354075,0.00016762766,0.0008133972],"domain_scores_gemma":[0.9987777,0.00012909077,0.00035636517,0.00044375393,0.000093639566,0.00019943906],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001460477,0.0003491302,0.0007912967,0.0001226629,0.00020628754,0.000017573511,0.00042239172,0.00037189497,0.006763713],"category_scores_gemma":[0.00009249735,0.00034679184,0.00028453534,0.00024262637,0.00013730451,0.00021053091,0.0001520547,0.0013633047,0.0038763776],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00079617865,0.00079988065,0.8039635,0.0066596954,0.00078890496,0.00019275941,0.00038508372,0.00012591618,0.048311394,0.0015324788,0.013729344,0.1227149],"study_design_scores_gemma":[0.0038910173,0.0011279458,0.07062725,0.0021062116,0.00050723786,0.00091298996,0.00002026803,0.0010807235,0.0061965385,0.00041596862,0.9124957,0.00061819406],"about_ca_topic_score_codex":0.000056943194,"about_ca_topic_score_gemma":0.00005038644,"teacher_disagreement_score":0.89876634,"about_ca_system_score_codex":0.00011535467,"about_ca_system_score_gemma":0.000046499288,"threshold_uncertainty_score":0.99989843},"labels":[],"label_agreement":null},{"id":"W2980391987","doi":"10.1155/2019/7348929","title":"Global Comparison of Stability Testing Parameters and Testing Methods for Finished Herbal Products","year":2019,"lang":"en","type":"review","venue":"Evidence-based Complementary and Alternative Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Ministry of Food and Drug Safety","keywords":"Harmonization; Product (mathematics); Agency (philosophy); Quality (philosophy); Business; Product testing; Commission; Human health; European commission; Risk-based testing; Medicine; Environmental health; European union; International trade; Marketing; Computer science; Mathematics","score_opus":0.8105395422768499,"score_gpt":0.6228817901342184,"score_spread":0.18765775214263147,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980391987","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011685131,0.9741407,0.0054113185,0.0007119675,0.001875727,0.0055152113,0.0004910166,0.000063345906,0.000105584586],"genre_scores_gemma":[0.061377198,0.79252297,0.1407419,0.0015124951,0.0018551016,0.0012619537,0.00058870664,0.0001086406,0.000031036285],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99388194,0.0029397176,0.0014619852,0.0009554009,0.00026323012,0.0004977216],"domain_scores_gemma":[0.98031634,0.017414032,0.0013578507,0.00031411255,0.00038245838,0.00021519866],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.005054232,0.00062791805,0.0023452903,0.00017205223,0.00035392298,0.00002233949,0.00037026443,0.00024508275,0.00011270665],"category_scores_gemma":[0.00493065,0.0005066315,0.00014187336,0.00067194056,0.000715622,0.00020891489,0.00018736492,0.0008737714,0.000001725825],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023903922,0.00016011963,0.01062509,0.022999626,0.00039545706,0.0000035008222,0.0002641369,0.00006515471,0.0002702109,0.000115291325,0.00013861137,0.96472377],"study_design_scores_gemma":[0.008554206,0.010867556,0.0011274763,0.07286922,0.010100418,0.00009849217,0.0008791034,0.061216246,0.007783273,0.0026788956,0.8216424,0.0021826955],"about_ca_topic_score_codex":0.0005801585,"about_ca_topic_score_gemma":0.00002717117,"teacher_disagreement_score":0.96254104,"about_ca_system_score_codex":0.00024007155,"about_ca_system_score_gemma":0.00035140448,"threshold_uncertainty_score":0.9997385},"labels":[],"label_agreement":null},{"id":"W2980816248","doi":"10.1056/nejmc1911063","title":"Drug-Induced Liver Injury — Types and Phenotypes","year":2019,"lang":"en","type":"letter","venue":"New England Journal of Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Phenotype; Liver injury; Drug; MEDLINE; Bioinformatics; Computational biology; Pharmacology; Genetics; Gene; Biology","score_opus":0.09896719180701125,"score_gpt":0.3861000618657783,"score_spread":0.28713287005876703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980816248","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.16069296,0.0073366505,0.00006831525,0.80460215,0.017936781,0.0007339314,0.00003778858,0.00005837022,0.008533072],"genre_scores_gemma":[0.24119487,0.0053811525,0.00014535304,0.6415256,0.09694797,0.0000062933705,0.000045670982,0.00010557961,0.014647504],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972356,0.00087369914,0.00073133694,0.0002856516,0.000462572,0.0004111584],"domain_scores_gemma":[0.99741673,0.0010700308,0.0008203315,0.00020153755,0.00024959375,0.00024175832],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0018841174,0.00041023758,0.0009237458,0.00043397862,0.00014145448,0.000020254645,0.00033150954,0.0011945546,0.0012898748],"category_scores_gemma":[0.00036078747,0.0003001355,0.00012314138,0.00017196265,0.00017366077,0.00016043414,0.00006107906,0.0068141315,0.00010631092],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005593676,0.000029384684,0.00031624883,0.00022690208,0.00033251516,0.0005408676,0.0012156543,0.000006143892,0.00500576,0.00002856693,0.75845444,0.23328416],"study_design_scores_gemma":[0.011835978,0.00085986056,0.00012706178,0.0003443563,0.000621958,0.0008774911,0.000033498847,0.000057426845,0.002872028,0.0008062878,0.98126704,0.0002970232],"about_ca_topic_score_codex":0.00018801793,"about_ca_topic_score_gemma":0.000032736556,"teacher_disagreement_score":0.23298715,"about_ca_system_score_codex":0.00009135101,"about_ca_system_score_gemma":0.00029617536,"threshold_uncertainty_score":0.9999451},"labels":[],"label_agreement":null},{"id":"W2990351701","doi":"","title":"Dose-dependent acute phase response of aqueous leaf decoction of Nerium oleander in Wistar rats.","year":2018,"lang":"en","type":"article","venue":"PubMed","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centennial College","funders":"","keywords":"Decoction; Traditional medicine; Medicine; Aqueous extract; Pharmacology; Acute toxicity; Dose dependence; Toxicity; Internal medicine","score_opus":0.13096408216709907,"score_gpt":0.41844246376970134,"score_spread":0.2874783816026023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2990351701","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939187,0.0001108829,0.00018627034,0.0004721344,0.0014567357,0.0011308417,0.00005681119,0.000055564826,0.002612028],"genre_scores_gemma":[0.99798506,0.000082768056,0.00004429487,0.00037812782,0.00019914149,0.00048251453,0.000008693992,0.000021465563,0.00079791446],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99764186,0.00092267594,0.00053234195,0.0002878804,0.00017908085,0.00043618688],"domain_scores_gemma":[0.99897414,0.00023169935,0.00027994034,0.00022833528,0.00013582139,0.00015004817],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022845338,0.00017581721,0.00032030567,0.00029860067,0.000105972824,0.000008214285,0.00019023448,0.00039209792,0.00019411987],"category_scores_gemma":[0.00018150422,0.00018091791,0.00009124831,0.00034021062,0.00029120728,0.00016298228,0.00005826604,0.00053552416,0.0000313689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0355465,0.0018474137,0.0024929773,0.000108417174,0.00033464233,0.00006857728,0.0024013373,0.00013332529,0.62659734,0.00015472807,0.0008603368,0.32945442],"study_design_scores_gemma":[0.0051794313,0.00039486762,0.023691345,0.000010712431,0.00011954165,0.00003147582,0.00013788117,0.0006844514,0.95392346,0.00035473835,0.015264395,0.00020768776],"about_ca_topic_score_codex":0.000114681025,"about_ca_topic_score_gemma":0.00018576958,"teacher_disagreement_score":0.32924673,"about_ca_system_score_codex":0.000143815,"about_ca_system_score_gemma":0.00008489187,"threshold_uncertainty_score":0.7377618},"labels":[],"label_agreement":null},{"id":"W2990551955","doi":"10.1186/s12876-019-1122-x","title":"Drug induced hepatitis mimicking Wilson’s disease secondary to the use of complex naturopathic regimens: a case report","year":2019,"lang":"en","type":"article","venue":"BMC Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; McMaster University; Regional Municipality of Waterloo","funders":"","keywords":"Medicine; Context (archaeology); Hepatitis; Internal medicine; Viral hepatitis; Liver injury; Hepatology; Liver disease; Gastroenterology","score_opus":0.17626065799171403,"score_gpt":0.37834212771686226,"score_spread":0.20208146972514823,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2990551955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928859,0.00003835964,0.00058078096,0.0021967494,0.0023864815,0.0015043832,0.0001646175,0.000089366666,0.0001533774],"genre_scores_gemma":[0.98871434,0.000014892998,0.00061521574,0.009702235,0.00021267908,0.00015183864,0.00005168485,0.00003954461,0.00049758755],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9960159,0.0018514189,0.000690482,0.0005946844,0.00019753198,0.00064995297],"domain_scores_gemma":[0.9979399,0.00041655306,0.00044998663,0.0006864667,0.00017124599,0.00033588134],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011202919,0.00031386613,0.00046358458,0.00021542811,0.00028719415,0.000029975905,0.00032848693,0.00026066275,0.0005494922],"category_scores_gemma":[0.0003065255,0.00027479147,0.00020163882,0.00020977484,0.0001517699,0.00020953099,0.00026734147,0.0013714997,0.000164573],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004033608,0.0005029569,0.93239784,0.00029906083,0.00027424304,0.009906648,0.001736986,0.003179099,0.03790838,0.00017876126,0.007193377,0.0023890194],"study_design_scores_gemma":[0.007656298,0.002136438,0.6603901,0.0001992215,0.00069358473,0.05159776,0.00053390325,0.026314346,0.011276982,0.0003099618,0.2378848,0.0010066214],"about_ca_topic_score_codex":0.00046915666,"about_ca_topic_score_gemma":0.0026105216,"teacher_disagreement_score":0.2720078,"about_ca_system_score_codex":0.000111730296,"about_ca_system_score_gemma":0.00015417083,"threshold_uncertainty_score":0.99997044},"labels":[],"label_agreement":null},{"id":"W2995245446","doi":"10.1002/ncp.10459","title":"Pathophysiology of Acute Liver Failure","year":2019,"lang":"en","type":"review","venue":"Nutrition in Clinical Practice","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":148,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta Hospital; University of Alberta; University of Toronto","funders":"","keywords":"Medicine; Pathophysiology; Sepsis; Acetaminophen; Coagulopathy; Liver injury; Hepatic encephalopathy; Encephalopathy; Liver disease; Systemic inflammatory response syndrome; Immunology; Internal medicine; Cirrhosis; Pharmacology","score_opus":0.44547997206687245,"score_gpt":0.6011493684976209,"score_spread":0.15566939643074845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2995245446","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00008015001,0.9887085,0.000041347907,0.0005956001,0.0038293826,0.002708139,0.0003493886,0.00006141041,0.0036261017],"genre_scores_gemma":[0.00011252778,0.99549,0.001127924,0.0014097412,0.0009744717,0.00037031868,0.0002047537,0.00004900044,0.0002612208],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.98890007,0.007407546,0.002339953,0.0007219388,0.00022217615,0.0004083385],"domain_scores_gemma":[0.9841196,0.013083868,0.0019137218,0.00046311136,0.00026076843,0.00015893255],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.004085461,0.00042482183,0.0023116057,0.00030309887,0.00009113242,0.000014765304,0.0004517077,0.003719184,0.00064707734],"category_scores_gemma":[0.0024572855,0.0004058569,0.00089938624,0.00057416153,0.00025794443,0.00038264223,0.00015471596,0.0062184315,0.0015658145],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048318232,0.0029959374,0.000010962924,0.016473914,0.00070095446,0.00015804595,0.000047701466,0.0000018763096,0.000023456312,0.0007323886,0.0064351694,0.9719364],"study_design_scores_gemma":[0.0015367017,0.00042262345,0.000007976162,0.002702373,0.002948274,0.000104911465,0.00002783826,0.000040421033,0.000018266643,0.00082160946,0.9910083,0.00036071055],"about_ca_topic_score_codex":0.000026756341,"about_ca_topic_score_gemma":0.000009080753,"teacher_disagreement_score":0.9845731,"about_ca_system_score_codex":0.00014008088,"about_ca_system_score_gemma":0.00035145186,"threshold_uncertainty_score":0.9998393},"labels":[],"label_agreement":null},{"id":"W2997511956","doi":"10.3390/ijms21010212","title":"Diagnostic Biomarkers in Liver Injury by Drugs, Herbs, and Alcohol: Tricky Dilemma after EMA Correctly and Officially Retracted Letter of Support","year":2019,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Medicine; Liver injury; Biomarker; Intensive care medicine; Pharmacology; Biology; Biochemistry","score_opus":0.09235357722929258,"score_gpt":0.4329169554320699,"score_spread":0.3405633782027774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2997511956","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23624898,0.759362,0.000055189805,0.00034766094,0.0029258402,0.00057759264,0.00015739247,0.0000067106334,0.0003186272],"genre_scores_gemma":[0.21180214,0.78716844,0.000082932245,0.00071461976,0.00015769017,0.000013123763,0.000011589418,0.000016123946,0.00003331673],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99727273,0.00069633813,0.00092279277,0.0003066602,0.0005713247,0.00023013918],"domain_scores_gemma":[0.9977001,0.0008641664,0.001009951,0.0000780318,0.0002291689,0.00011858631],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018665681,0.00026546948,0.0007332443,0.0007199008,0.00004971564,0.00006774754,0.0005179855,0.00046569135,0.00015095726],"category_scores_gemma":[0.0004033873,0.0002210581,0.00021056076,0.0003434035,0.0004160295,0.00028375947,0.00012529953,0.0010017577,0.000008360342],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002358914,0.00023663447,0.001569415,0.0008158529,0.00066151045,0.00058745826,0.0003144251,0.000008678388,0.001983479,0.00004541602,0.0011025347,0.99243873],"study_design_scores_gemma":[0.0015900696,0.00068801036,0.0011702859,0.0044654296,0.0008799149,0.0010830736,0.00006262306,0.00016009726,0.0051000137,0.00012772481,0.98402995,0.00064278534],"about_ca_topic_score_codex":0.00005430023,"about_ca_topic_score_gemma":0.000012457305,"teacher_disagreement_score":0.9917959,"about_ca_system_score_codex":0.0000826249,"about_ca_system_score_gemma":0.00041455886,"threshold_uncertainty_score":0.9014488},"labels":[],"label_agreement":null},{"id":"W2999061288","doi":"10.1007/978-3-030-24432-3_7","title":"Hepatotoxicity: Mechanisms of Liver Injury","year":2020,"lang":"en","type":"book-chapter","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Medicine; Steatohepatitis; Liver disease; Disease; Fatty liver; Liver injury; Pharmacology; Hepatitis; Cirrhosis; Toxic hepatitis; Environmental health; Population; Liver toxicity; Intensive care medicine; Toxicity; Pathology; Immunology; Internal medicine","score_opus":0.15752012288544165,"score_gpt":0.38338916427119213,"score_spread":0.22586904138575048,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2999061288","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00067456556,0.0002992147,0.0031714041,0.00059778144,0.0018604976,0.0014591487,0.0005291329,0.00037185175,0.9910364],"genre_scores_gemma":[0.44662,0.0016743793,0.0010764379,0.008690636,0.0009755999,0.00009087249,0.00014664291,0.00023441894,0.54049104],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976145,0.00018938874,0.0007718495,0.0006561753,0.00037540137,0.00039270733],"domain_scores_gemma":[0.99832505,0.00020585668,0.00054624793,0.000372764,0.00017821832,0.00037187856],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.00056041894,0.0006186164,0.0008878061,0.000266785,0.00019996107,0.000016114562,0.00045605138,0.0022904288,0.015701998],"category_scores_gemma":[0.000051949442,0.00063582236,0.00044828403,0.000087198954,0.00023929104,0.00011864652,0.00026242464,0.0026722827,0.0021317755],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006195725,0.00013261591,0.000012886942,0.00044996926,0.0006333,0.000117322386,0.00019590351,0.000009735063,0.08002943,0.87015367,0.008979933,0.038665652],"study_design_scores_gemma":[0.00049501675,0.0005294057,0.0000045494085,0.000080460675,0.00034278134,0.000024760264,0.000010191751,0.0007635474,0.3677573,0.1218251,0.50749654,0.0006703709],"about_ca_topic_score_codex":0.000055733723,"about_ca_topic_score_gemma":0.00004110938,"teacher_disagreement_score":0.74832857,"about_ca_system_score_codex":0.0001316466,"about_ca_system_score_gemma":0.00019640492,"threshold_uncertainty_score":0.9996286},"labels":[],"label_agreement":null},{"id":"W2999405789","doi":"10.1007/s13181-020-00757-9","title":"Adducts Post Acetaminophen Overdose Treated with a 12-Hour vs 20-Hour Acetylcysteine Infusion","year":2020,"lang":"en","type":"article","venue":"Journal of Medical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Health and Medical Research Council","keywords":"Acetaminophen; Acetylcysteine; Medicine; Regimen; acetaminophen overdose; Alanine transaminase; Adduct; Gastroenterology; Internal medicine; Antidote; Anesthesia; Toxicity; Chemistry; Biochemistry","score_opus":0.10424451070313884,"score_gpt":0.38857510188917427,"score_spread":0.28433059118603543,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2999405789","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93418,0.00044726822,0.00039318315,0.061370924,0.0013729709,0.0005494975,0.000037278838,0.000101123085,0.001547751],"genre_scores_gemma":[0.970663,0.000508171,0.00029581622,0.025669333,0.0023853702,0.00002114201,0.000016763861,0.000054383643,0.00038602497],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99510723,0.0015278233,0.0011204674,0.00041639202,0.0010903,0.00073779497],"domain_scores_gemma":[0.9962044,0.00067613355,0.00089128746,0.00020026295,0.00042114113,0.001606811],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0021428063,0.0004302743,0.0010110923,0.00026504096,0.0002967424,0.000034659628,0.00080582337,0.0015921284,0.006544392],"category_scores_gemma":[0.0015526782,0.00032452622,0.00024793495,0.00048248732,0.00039525796,0.00031338635,0.00022925717,0.0039020195,0.00023849068],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0357315,0.0041677426,0.027152063,0.0006997689,0.0027065058,0.011451065,0.006792309,0.0012664952,0.6951848,0.0008996697,0.066969015,0.14697903],"study_design_scores_gemma":[0.03401756,0.023950508,0.0103348065,0.00038591938,0.0011156378,0.0067793084,0.0009287267,0.006723474,0.14597301,0.00023200555,0.7683649,0.0011941523],"about_ca_topic_score_codex":0.000030378194,"about_ca_topic_score_gemma":0.00009490421,"teacher_disagreement_score":0.70139587,"about_ca_system_score_codex":0.00021289868,"about_ca_system_score_gemma":0.0008481539,"threshold_uncertainty_score":0.99992067},"labels":[],"label_agreement":null},{"id":"W3004331558","doi":"10.14740/gr1254","title":"Concomitant Acute Hepatic Failure and Renal Failure Induced by Intravenous Amiodarone: A Case Report and Literature Review","year":2020,"lang":"en","type":"article","venue":"Gastroenterology Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Amiodarone; Concomitant; Internal medicine; Creatinine; Renal function; Heart failure; Blood urea nitrogen; Coronary artery disease; Gastroenterology; Aspartate transaminase; Cardiology; Atrial fibrillation","score_opus":0.10562427741278173,"score_gpt":0.42716466456372837,"score_spread":0.3215403871509466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3004331558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9519935,0.005114219,0.000093982795,0.040842764,0.00013587408,0.0014316009,0.00019243814,0.00008306873,0.000112501024],"genre_scores_gemma":[0.9828719,0.007908667,0.00023624122,0.00826447,0.00024234041,0.00023832078,0.00011132934,0.000035611632,0.00009115713],"study_design_codex":"bench_or_experimental","study_design_gemma":"case_report","domain_scores_codex":[0.9946581,0.0026645614,0.00058489724,0.0008331837,0.00029915938,0.0009600968],"domain_scores_gemma":[0.99823654,0.00027593633,0.00017877303,0.00028960264,0.00027886342,0.0007402834],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0023597758,0.00034639443,0.000641031,0.00016258167,0.0006364647,0.0000838307,0.00024435134,0.0006646651,0.00017133229],"category_scores_gemma":[0.00042560074,0.0003198175,0.00007956829,0.00044029907,0.0005549487,0.00021181263,0.00034743643,0.004288547,0.000031476156],"study_design_candidate":"case_report","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033856868,0.0005208932,0.029176217,0.003753504,0.0015089889,0.2867039,0.0069552176,0.0000026280347,0.5651083,0.00014364807,0.09112589,0.011615119],"study_design_scores_gemma":[0.012113853,0.01004292,0.0028382554,0.0020936616,0.0011876101,0.82668424,0.0017379349,0.0023511944,0.027005909,0.000504234,0.11217121,0.0012689874],"about_ca_topic_score_codex":0.000039239854,"about_ca_topic_score_gemma":0.00018707843,"teacher_disagreement_score":0.5399803,"about_ca_system_score_codex":0.00007438173,"about_ca_system_score_gemma":0.00009262152,"threshold_uncertainty_score":0.9999254},"labels":[],"label_agreement":null},{"id":"W3004428517","doi":"10.1139/cjpp-2019-0633","title":"Pharmacokinetics and tissue distribution study of herpetotriol in rats by ultrahigh-performance liquid chromatography with tandem mass spectrometry","year":2020,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Pharmacokinetics; Chromatography; Chemistry; Liquid chromatography–mass spectrometry; Pharmacology; Tandem mass spectrometry; High-performance liquid chromatography; Elimination rate constant; Distribution (mathematics); Kidney; Tissue distribution; Mass spectrometry; Medicine; Volume of distribution; Internal medicine","score_opus":0.03389380256854331,"score_gpt":0.32275233418774446,"score_spread":0.28885853161920116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3004428517","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965621,0.0012798068,0.00007452823,0.0007741768,0.0005586622,0.00056692096,0.00010125172,0.000010997345,0.00007154168],"genre_scores_gemma":[0.99757284,0.0010278479,0.00003908233,0.0010295092,0.00026729447,0.000019058807,0.000018760742,0.000018583789,0.000007008338],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99779,0.00073242973,0.00058871304,0.00030866414,0.00010009042,0.0004801511],"domain_scores_gemma":[0.99849457,0.00021009221,0.00041608568,0.00006843689,0.00013567018,0.00067516],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048794813,0.0002739481,0.00061731244,0.00027808655,0.00021786317,0.000008551593,0.00022049138,0.00033545014,0.00050515577],"category_scores_gemma":[0.000024176687,0.00025197302,0.000041142008,0.0005883893,0.0005655457,0.00018416696,0.000021819566,0.0013545367,0.000002699115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016063518,0.00022904048,0.029474828,0.00016437566,0.00032132884,0.00012255572,0.0016980171,0.00045817214,0.9640063,0.000016305656,0.0010049613,0.0008977528],"study_design_scores_gemma":[0.006025535,0.00783141,0.013929178,0.000026641992,0.00031745885,0.0001521475,0.0005088532,0.0005204916,0.9607209,0.00005761346,0.00959198,0.000317767],"about_ca_topic_score_codex":0.00021592515,"about_ca_topic_score_gemma":0.0003101619,"teacher_disagreement_score":0.015545651,"about_ca_system_score_codex":0.00006562443,"about_ca_system_score_gemma":0.00027024848,"threshold_uncertainty_score":0.99999326},"labels":[],"label_agreement":null},{"id":"W3005191572","doi":"10.14740/gr1188","title":"Mifepristone: An Uncommon Cause of Drug-Induced Liver Injury","year":2019,"lang":"en","type":"article","venue":"Gastroenterology Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Mifepristone; Medicine; Liver injury; Jaundice; Drug; Abdominal pain; Liver biopsy; Gastroenterology; Internal medicine; Surgery; Biopsy; Pharmacology; Pregnancy","score_opus":0.2612162519554892,"score_gpt":0.5053005270440135,"score_spread":0.24408427508852432,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3005191572","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99364233,0.00005233409,0.000017696557,0.0005580111,0.0012856926,0.001029807,0.000052539643,0.00008344807,0.003278113],"genre_scores_gemma":[0.99785,0.00009653054,0.000087731896,0.0006407108,0.00022402291,0.0001093652,0.000031081876,0.000038741266,0.0009218383],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9932266,0.004066257,0.00050981564,0.00061615376,0.00046685882,0.0011143085],"domain_scores_gemma":[0.9980328,0.00036632866,0.000171205,0.0006601349,0.0004018992,0.00036760143],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0043004137,0.0002550937,0.00048307894,0.00056684593,0.0003018149,0.000018994167,0.0006977365,0.0005700885,0.0016037219],"category_scores_gemma":[0.00010866336,0.0002610187,0.00012760292,0.0004082799,0.0004519625,0.00027726268,0.0003372221,0.002977785,0.0009776427],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003954752,0.0010087314,0.63629526,0.0001427264,0.00019190637,0.000057782625,0.0014022209,0.000059943373,0.34825513,0.0005208872,0.0021074105,0.0060032695],"study_design_scores_gemma":[0.008706331,0.007913994,0.3795008,0.00010255932,0.00017080801,0.0002915421,0.0014527554,0.005170367,0.57082814,0.0018934929,0.023237925,0.00073125],"about_ca_topic_score_codex":0.00047782212,"about_ca_topic_score_gemma":0.00057490886,"teacher_disagreement_score":0.25679442,"about_ca_system_score_codex":0.0001632465,"about_ca_system_score_gemma":0.00013309244,"threshold_uncertainty_score":0.9999842},"labels":[],"label_agreement":null},{"id":"W3006531513","doi":"10.1016/j.clinbiochem.2020.02.006","title":"Defining appropriate utilization of AST testing","year":2020,"lang":"en","type":"article","venue":"Clinical Biochemistry","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Quality (philosophy); Liver injury; Medicine; Intensive care medicine; Internal medicine; Pharmacology; Physics","score_opus":0.44585360207965546,"score_gpt":0.5088979181931852,"score_spread":0.06304431611352973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3006531513","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9843744,0.0002269379,0.0007231336,0.00075261854,0.00049051445,0.00018469845,0.000041212777,0.00013619293,0.013070296],"genre_scores_gemma":[0.99661124,0.000044187174,0.0011372248,0.0016325992,0.00044568357,0.000011548199,0.000034923163,0.000014761567,0.0000678333],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998461,0.00022392097,0.0006442691,0.000352367,0.00010799845,0.00021041768],"domain_scores_gemma":[0.9984877,0.0006986423,0.000302469,0.00014414218,0.00012307364,0.00024396738],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008608234,0.00013646946,0.00026614234,0.000014997744,0.000114848684,0.000008734415,0.00019352285,0.0005771661,0.00022535892],"category_scores_gemma":[0.0037257585,0.00014156224,0.00011525764,0.00029257787,0.00019399708,0.000044147895,0.00009377008,0.00095071347,0.0001165323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040834866,0.00042093915,0.08757281,0.00050469703,0.00012951563,0.000013192756,0.00026287086,0.00021049264,0.660715,0.0003249994,0.0010491632,0.24838799],"study_design_scores_gemma":[0.0010383853,0.00016319494,0.0015643905,0.00004029376,0.00007537433,0.000005780301,0.00008718482,0.010434915,0.97654,0.00030608472,0.009539901,0.00020444754],"about_ca_topic_score_codex":0.000004014882,"about_ca_topic_score_gemma":2.7133123e-7,"teacher_disagreement_score":0.31582507,"about_ca_system_score_codex":0.000016809654,"about_ca_system_score_gemma":0.000112944086,"threshold_uncertainty_score":0.5772741},"labels":[],"label_agreement":null},{"id":"W3010030124","doi":"10.1371/journal.pone.0229070","title":"Public awareness of acetaminophen and risks of drug induced liver injury: Results of a large outpatient clinic survey","year":2020,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Dalhousie University; University of British Columbia","funders":"","keywords":"Acetaminophen; Medicine; Outpatient clinic; Harm; Adverse effect; Drug; Internal medicine; Family medicine; Anesthesia; Pharmacology; Psychology","score_opus":0.624272761995722,"score_gpt":0.4530241885893819,"score_spread":0.1712485734063401,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3010030124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966684,0.00016273285,0.000011756007,0.00045753355,0.00014843112,0.00072195934,0.0013365851,0.00003270718,0.00045990906],"genre_scores_gemma":[0.9990544,0.00032490038,0.00008698714,0.00028714663,0.00006408459,0.000030010402,0.00007297284,0.000018774052,0.00006072917],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968503,0.0014645022,0.0008030388,0.00032457712,0.00028158954,0.00027599034],"domain_scores_gemma":[0.99780864,0.0006843871,0.00067674153,0.00021712465,0.00041080418,0.00020233163],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021351194,0.00017868857,0.00063033507,0.00012663564,0.000093130744,0.0000057283414,0.00022938917,0.00038792982,0.0001798397],"category_scores_gemma":[0.0013988334,0.00018318986,0.000074994896,0.0004155261,0.00015039174,0.00013687082,0.00018986462,0.0007531137,0.000020082487],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006717225,0.0089636315,0.515861,0.0020005202,0.0014186226,0.000005093536,0.012316073,0.0000070065585,0.44548464,0.00013131458,0.00049708056,0.0065978523],"study_design_scores_gemma":[0.0034978013,0.0010663791,0.099233165,0.000091342,0.00026775294,3.1571085e-7,0.00016989972,0.0015990161,0.89347434,0.000061361425,0.00032733553,0.00021127441],"about_ca_topic_score_codex":0.00054179574,"about_ca_topic_score_gemma":0.00023880348,"teacher_disagreement_score":0.44798973,"about_ca_system_score_codex":0.000023819193,"about_ca_system_score_gemma":0.0001438783,"threshold_uncertainty_score":0.74702656},"labels":[],"label_agreement":null},{"id":"W3010132215","doi":"10.5539/jas.v12n4p298","title":"Effect of Introducing the Jordanian Common Rue (Ruta chalepensis L.) on Liver Enzymes and Lipid Peroxidation in Adult Male Sprague Dawley Rats Toxified With Paracetamol","year":2020,"lang":"en","type":"article","venue":"Journal of Agricultural Science","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"University of Jordan","keywords":"Lipid peroxidation; Bilirubin; Ingestion; Alanine aminotransferase; Liver injury; Liver enzyme; Toxicity; Body weight; Biology; Enzyme; Pharmacology; Animal science; Internal medicine; Endocrinology; Biochemistry; Medicine","score_opus":0.038659432353881786,"score_gpt":0.33244494352901083,"score_spread":0.293785511175129,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3010132215","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940872,0.00012005685,0.000010559065,0.0048032994,0.00033301045,0.000405128,0.0000026143439,0.000007175767,0.00023096312],"genre_scores_gemma":[0.99894005,0.00014876171,0.000058335478,0.00047792186,0.0003453866,0.0000060605216,0.0000013024893,0.0000037458162,0.000018456332],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99829596,0.00059695134,0.00033957127,0.00021036461,0.00032979247,0.00022738212],"domain_scores_gemma":[0.9987557,0.00039180074,0.0004138172,0.00007684372,0.00020171137,0.00016011401],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016633112,0.00015431098,0.00028355047,0.00008235593,0.00027744478,0.000058284415,0.00028895383,0.00010236452,0.00003622346],"category_scores_gemma":[0.0003234316,0.00007431221,0.000051155122,0.00059984915,0.00028356168,0.0004902419,0.000053597116,0.0008706918,0.0000058924643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010963903,0.00008586679,0.008923863,0.000075745425,0.00003293215,0.000033271834,0.0036144068,0.0026887523,0.96516,0.000254297,0.00019235346,0.017842088],"study_design_scores_gemma":[0.0010513772,0.0022802367,0.084527776,0.0001124402,0.00006976647,0.0003961131,0.0004574262,0.0014820645,0.90915424,0.000005114995,0.00032198863,0.00014144943],"about_ca_topic_score_codex":0.000062768275,"about_ca_topic_score_gemma":0.0000865935,"teacher_disagreement_score":0.07560391,"about_ca_system_score_codex":0.000072024915,"about_ca_system_score_gemma":0.000044413446,"threshold_uncertainty_score":0.3782771},"labels":[],"label_agreement":null},{"id":"W3010290644","doi":"10.1007/s10620-020-06166-w","title":"Elevated Serum Liver-Type Fatty Acid Binding Protein Levels in Non-acetaminophen Acute Liver Failure Patients with Organ Dysfunction","year":2020,"lang":"en","type":"article","venue":"Digestive Diseases and Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Blood Services; Translational Research in Oncology; Université de Montréal; University of Alberta","funders":"Baylor University Medical Center; Ministero dello Sviluppo Economico; Astellas Pharma; University of Alberta; University of California, San Diego; University of Oregon; University of Pittsburgh; University of California, Los Angeles; University of South Carolina; National Institute of Diabetes and Digestive and Kidney Diseases; Baylor University; Yale University; Virginia Commonwealth University; Northwestern University; National Institutes of Health; Ohio State University; University of Washington; Emory University; University of Pennsylvania; Massachusetts General Hospital","keywords":"Hepatology; Transplant surgery; Internal medicine; Acetaminophen; Medicine; Gastroenterology; Liver failure; Fatty liver; Organ dysfunction; Endocrinology; Pharmacology; Sepsis; Disease","score_opus":0.0737985869600312,"score_gpt":0.3312544290709402,"score_spread":0.257455842110909,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3010290644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99779487,0.000097002514,0.000088570094,0.0004828357,0.00017578046,0.0009769923,0.00022306762,0.00006397188,0.00009688724],"genre_scores_gemma":[0.9992193,0.000033525797,0.00011592306,0.00042319697,0.00006823718,0.000050547133,0.000034432796,0.00001209868,0.000042748034],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984218,0.0002327538,0.00019193263,0.0005170293,0.0002432082,0.00039326664],"domain_scores_gemma":[0.99930406,0.00006943226,0.00013088157,0.000068556445,0.00013172494,0.00029531954],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000199533,0.0002354619,0.0002280577,0.00011733803,0.0006217643,0.00008391138,0.00018150627,0.00016419844,0.00020373805],"category_scores_gemma":[0.00010361447,0.00018727053,0.0000359555,0.00087839446,0.00038261674,0.0005639733,0.00008435679,0.00041950028,0.000049274327],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043859062,0.00019577726,0.937926,0.00006251789,0.000064267006,0.000042066626,0.0012224301,0.000095293246,0.054954123,0.000054530963,0.000030996544,0.0049133915],"study_design_scores_gemma":[0.0014063952,0.0008406377,0.95061105,0.000056892874,0.00010096974,0.000002246882,0.000391078,0.0032163507,0.042758867,0.000030706164,0.0002758777,0.00030890177],"about_ca_topic_score_codex":0.00004076419,"about_ca_topic_score_gemma":0.000019716805,"teacher_disagreement_score":0.0126850605,"about_ca_system_score_codex":0.0000564187,"about_ca_system_score_gemma":0.00012568028,"threshold_uncertainty_score":0.76366705},"labels":[],"label_agreement":null},{"id":"W3015300982","doi":"10.24095/hpcdp.40.4.05","title":"At-a-glance - Trends in emergency department visits for acetaminophen-related poisonings: 2011–2019","year":2020,"lang":"en","type":"article","venue":"Health Promotion and Chronic Disease Prevention in Canada","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"Public Health Agency of Canada","funders":"","keywords":"Medicine; Emergency department; Pediatrics; Humanities; Gynecology; Medical emergency; Psychiatry; Art","score_opus":0.10042878952179907,"score_gpt":0.4182013594053784,"score_spread":0.3177725698835793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3015300982","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96408504,0.003864432,0.00020159819,0.02799669,0.0012722007,0.001980889,0.00027158996,0.000053806307,0.00027374743],"genre_scores_gemma":[0.9956633,0.0012490753,0.000021012995,0.00096458814,0.00009989736,0.00046320702,0.0003517872,0.00001717445,0.0011699774],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99780136,0.00050918676,0.0006282487,0.00042731914,0.00015542764,0.00047847632],"domain_scores_gemma":[0.9990438,0.00003208414,0.00025895235,0.00009906912,0.0000313331,0.0005347348],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00050407357,0.00018474452,0.00025292268,0.00010514067,0.0002441603,0.0000069427037,0.000091549,0.00012415953,0.002329953],"category_scores_gemma":[0.00002621043,0.00021029226,0.000060279668,0.00026396938,0.000019483352,0.00013172471,0.00004328126,0.00038803325,0.00001897021],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021342817,0.0019999288,0.2039031,0.0053673466,0.00023476641,0.0000777768,0.0023126593,0.0056890915,0.0014047852,0.0023247139,0.06033599,0.7142156],"study_design_scores_gemma":[0.019274374,0.001854844,0.6611021,0.00047609332,0.00014808004,0.000012567865,0.00020443973,0.112164654,0.0012980835,0.0032919375,0.19893909,0.0012337407],"about_ca_topic_score_codex":0.02990884,"about_ca_topic_score_gemma":0.5589095,"teacher_disagreement_score":0.7129818,"about_ca_system_score_codex":0.0021032766,"about_ca_system_score_gemma":0.0015071229,"threshold_uncertainty_score":0.99858207},"labels":[],"label_agreement":null},{"id":"W3019137182","doi":"10.4254/wjh.v12.i4.125","title":"Liver injury induced by paracetamol and challenges associated with intentional and unintentional use","year":2020,"lang":"en","type":"review","venue":"World Journal of Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":159,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Valeant Pharmaceuticals International; Allergan; Exelixis; BeiGene; Gilead Sciences","keywords":"Medicine; Acetaminophen; Liver injury; Intensive care medicine; Drug; Drug overdose; Liver failure; Ingestion; Toxicity; Liver toxicity; Poison control; Pharmacology; Internal medicine; Emergency medicine","score_opus":0.2786398623051659,"score_gpt":0.42341218634808814,"score_spread":0.14477232404292223,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3019137182","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007521108,0.98934895,0.0000189091,0.0014572715,0.00081341184,0.0005063151,0.00015653635,0.000029290806,0.00014823837],"genre_scores_gemma":[0.016232595,0.9825929,0.00006875428,0.0004898089,0.00020231154,0.000033734792,0.00005137493,0.00004763879,0.00028091512],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99588084,0.0021040777,0.0009751425,0.0004113894,0.00024574733,0.00038281817],"domain_scores_gemma":[0.9965266,0.0012192992,0.0014834475,0.000105781626,0.00029543592,0.0003694429],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0010154919,0.0004985608,0.0018472065,0.0005356115,0.00023153546,0.000045606208,0.00023449647,0.000873813,0.00021360272],"category_scores_gemma":[0.00036277217,0.00040025346,0.00027037162,0.0003295232,0.00038860858,0.00029247763,0.0001347444,0.003361301,0.000015775318],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005052723,0.0003715913,0.0010248224,0.0020282124,0.0027902762,0.0005170219,0.00016785407,3.7714977e-7,0.000064057625,0.0022549268,0.0026426665,0.98763293],"study_design_scores_gemma":[0.0009816315,0.00057282345,0.0002061146,0.0016766965,0.001631201,0.002096245,0.000025309515,0.000058002246,0.000024231242,0.00017865408,0.99216455,0.0003845342],"about_ca_topic_score_codex":0.000013940837,"about_ca_topic_score_gemma":0.00014112609,"teacher_disagreement_score":0.98952186,"about_ca_system_score_codex":0.00017467114,"about_ca_system_score_gemma":0.00038352978,"threshold_uncertainty_score":0.9998449},"labels":[],"label_agreement":null},{"id":"W3023257423","doi":"10.1503/cmaj.191532","title":"Warfarin and acetaminophen interaction in a 47-year-old woman","year":2020,"lang":"en","type":"article","venue":"Canadian Medical Association Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Warfarin; Medicine; Acetaminophen; Medical history; Medical prescription; Past medical history; Mitral valve replacement; Rheumatic disease; Surgery; Mitral valve; Internal medicine; Anesthesia; Disease; Atrial fibrillation; Nursing","score_opus":0.07609148284783174,"score_gpt":0.368018943996506,"score_spread":0.29192746114867424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3023257423","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91842496,0.00010293548,0.000038163475,0.07508819,0.0011816672,0.0001752535,0.000014589251,0.000025493553,0.004948757],"genre_scores_gemma":[0.9625197,0.00024573575,0.000028246151,0.035809543,0.0011265256,0.000010310138,0.0000048935603,0.000010820165,0.00024421088],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981886,0.00055071124,0.00034196573,0.00016859219,0.00035574133,0.0003943454],"domain_scores_gemma":[0.9980291,0.0001831251,0.00015108926,0.000037325513,0.00008692915,0.001512423],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015389445,0.000112671776,0.00018280462,0.00015026589,0.0002487557,0.000058161993,0.00013393801,0.00064968545,0.0035818885],"category_scores_gemma":[0.0012298857,0.000118798795,0.0000470333,0.00024111346,0.00003411607,0.00019937,0.000022275484,0.0028201456,0.0002222376],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024085162,0.00013860138,0.6057555,0.00006244022,0.00028763365,0.0010295134,0.009201331,0.00014276213,0.0018346632,0.0010478639,0.066300645,0.3139582],"study_design_scores_gemma":[0.0025794941,0.0001230983,0.052732762,0.000040291096,0.000034112825,0.00023238706,0.0011293257,0.0067286934,0.0006197485,0.00038683976,0.93514025,0.00025302486],"about_ca_topic_score_codex":0.001462371,"about_ca_topic_score_gemma":0.01710916,"teacher_disagreement_score":0.86883956,"about_ca_system_score_codex":0.000711107,"about_ca_system_score_gemma":0.00055534806,"threshold_uncertainty_score":0.99948037},"labels":[],"label_agreement":null},{"id":"W3024267585","doi":"10.1111/bcp.14294","title":"Liver injury associated with the analgetic drug metamizole","year":2020,"lang":"en","type":"letter","venue":"British Journal of Clinical Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Liver injury; Azathioprine; Drug; Metamizole; Etiology; Intensive care medicine; Population; Internal medicine; Pharmacology; Analgesic","score_opus":0.16989803551221747,"score_gpt":0.4559118387883964,"score_spread":0.286013803276179,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3024267585","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10966917,0.0043683923,0.00012704615,0.8628435,0.0189691,0.0015097143,0.00043707443,0.00014512557,0.0019308748],"genre_scores_gemma":[0.1360392,0.0053521614,0.000063904015,0.8331744,0.023048801,0.00005552065,0.000072680894,0.00012321306,0.0020701014],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9832373,0.011749704,0.0026160004,0.00065804634,0.00078802503,0.0009508822],"domain_scores_gemma":[0.9880141,0.006625359,0.003711737,0.00021367962,0.0009016821,0.00053342944],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0060766162,0.00061826996,0.0021342873,0.00021401128,0.0006831588,0.00012067017,0.0015617983,0.0024087077,0.0033088592],"category_scores_gemma":[0.0014283508,0.00051341776,0.0011487509,0.0005957186,0.0013730639,0.0002898543,0.00023474095,0.030183813,0.00021893684],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010937456,0.00046465953,0.00023418498,0.0000958109,0.0034343433,0.018779699,0.00012097288,0.0000781107,0.00021659838,0.0000026417376,0.9408335,0.03464572],"study_design_scores_gemma":[0.004458301,0.0010095474,0.0008652372,0.0001736183,0.0037547583,0.0020798717,0.000030036043,0.00046661677,0.000971971,0.00021986524,0.9853817,0.00058844464],"about_ca_topic_score_codex":0.000054557953,"about_ca_topic_score_gemma":0.000064717904,"teacher_disagreement_score":0.044548217,"about_ca_system_score_codex":0.00017782561,"about_ca_system_score_gemma":0.0009370851,"threshold_uncertainty_score":0.9997317},"labels":[],"label_agreement":null},{"id":"W3024364032","doi":"10.1017/cem.2020.330","title":"P125: Low dose intravenous ketorolac in renal colic, a pilot randomized controlled trial","year":2020,"lang":"en","type":"article","venue":"Canadian Journal of Emergency Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Ketorolac; Renal colic; Randomized controlled trial; Emergency department; Dosing; Adverse effect; Anesthesia; Internal medicine; Analgesic","score_opus":0.2181133761026257,"score_gpt":0.4262369690880275,"score_spread":0.20812359298540178,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3024364032","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.937216,0.0028507898,0.00023463604,0.02108163,0.024720259,0.00449233,0.000021560878,0.000022255592,0.009360574],"genre_scores_gemma":[0.9907341,0.0010159328,0.000018556108,0.0024801665,0.0052388115,0.00011042702,0.0000056163303,0.000025717,0.00037067322],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99492455,0.002011329,0.0019976427,0.00022199214,0.00027981334,0.00056467316],"domain_scores_gemma":[0.996559,0.0005414569,0.00082651206,0.000113624985,0.0002978758,0.0016615168],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0048348554,0.0002895054,0.0018030871,0.00047593145,0.00020571334,0.000007018223,0.00035489758,0.00030204147,0.012395567],"category_scores_gemma":[0.00449498,0.00022534898,0.00035268642,0.000552499,0.00025097496,0.00013677677,0.000011254389,0.0017752323,0.000041807398],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9686675,0.00017955195,0.00022919555,0.000060434206,0.0005294662,0.00044777198,0.0051199025,0.00036283082,0.008790747,0.00035737193,0.013510403,0.0017448306],"study_design_scores_gemma":[0.95015645,0.002675609,0.00009384743,0.00010079163,0.00043722836,0.000028180495,0.00019486682,0.0014452324,0.000533084,0.00066945545,0.043432504,0.00023273927],"about_ca_topic_score_codex":0.0032470808,"about_ca_topic_score_gemma":0.010982855,"teacher_disagreement_score":0.053518135,"about_ca_system_score_codex":0.00020943818,"about_ca_system_score_gemma":0.0014590488,"threshold_uncertainty_score":0.9885072},"labels":[],"label_agreement":null},{"id":"W3024535437","doi":"10.22374/cjgim.v14i4.339","title":"Minding The Gap: Severe Anion Gap Metabolic Acidosis Associated With 5-Oxoproline Secondary To Chronic Acetaminophen Use","year":2019,"lang":"en","type":"article","venue":"Canadian Journal of General Internal Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; University of Toronto","funders":"","keywords":"Anion gap; Acetaminophen; Metabolic acidosis; Medicine; Internal medicine; Acidosis; Gastroenterology; Abdominal pain; Anesthesia","score_opus":0.11182875447174491,"score_gpt":0.3663012011446506,"score_spread":0.2544724466729057,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3024535437","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9841727,0.0015415951,0.00012390545,0.0069550322,0.0040276647,0.00049705425,0.000056143846,0.000012298741,0.0026135775],"genre_scores_gemma":[0.98363805,0.00011813934,0.000065054475,0.006834415,0.001992113,0.000011511196,0.00001407814,0.000034873225,0.0072917948],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977477,0.0005407536,0.0005803716,0.00022896896,0.0003132736,0.000588917],"domain_scores_gemma":[0.9978258,0.00022812132,0.00047036159,0.00019341786,0.00033182112,0.0009504803],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015890482,0.00028027483,0.00052037963,0.00044910453,0.00027821385,0.000055297256,0.0005369992,0.0002696983,0.0030855194],"category_scores_gemma":[0.0003315922,0.00018116597,0.00011160927,0.00041460025,0.00017569687,0.0003120309,0.00003352473,0.0018639498,0.000078660065],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003056559,0.0002416799,0.2875268,0.00020617998,0.0059477775,0.0020334907,0.01709029,0.012707314,0.4216909,0.0016265656,0.08624571,0.16162673],"study_design_scores_gemma":[0.014108201,0.006759292,0.13072966,0.0020000322,0.0016152257,0.0048035826,0.0011626913,0.003899106,0.088279925,0.0005486351,0.74481595,0.0012777274],"about_ca_topic_score_codex":0.0060604913,"about_ca_topic_score_gemma":0.031013519,"teacher_disagreement_score":0.65857023,"about_ca_system_score_codex":0.0006061772,"about_ca_system_score_gemma":0.00090665126,"threshold_uncertainty_score":0.9978258},"labels":[],"label_agreement":null},{"id":"W3026966500","doi":"10.47883/jszmc.v11i01.50","title":"Impact of Co-enzyme Q-10 on Liver Functions and Histology in INH Induced Rat Model","year":2020,"lang":"en","type":"article","venue":"Journal of Sheikh Zayed Medical College","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Humber Polytechnic","funders":"","keywords":"Isoniazid; Medicine; Hepatitis; Liver function; Liver function tests; Internal medicine; Liver enzyme; Liver injury; Enzyme; Liver disease; Tuberculosis; Gastroenterology; Pharmacology; Immunology; Chemistry; Pathology; Biochemistry","score_opus":0.17333489365025076,"score_gpt":0.4329827774910291,"score_spread":0.2596478838407783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3026966500","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923103,0.0002729797,0.0002831614,0.003789363,0.0005514646,0.00029627827,0.000057917237,0.000015500495,0.0024230608],"genre_scores_gemma":[0.997191,0.00026454078,0.000059114056,0.0019784514,0.0003000117,0.000008630968,0.0000034624713,0.000015926562,0.00017887323],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99771124,0.0005834712,0.00079144846,0.00020233316,0.00040497506,0.00030653185],"domain_scores_gemma":[0.99811536,0.0005191586,0.00041182927,0.00008970219,0.00016176158,0.00070217735],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0012058509,0.0002033468,0.000596458,0.00030709623,0.00012021277,0.0000058152195,0.00022178804,0.0007457355,0.0017675372],"category_scores_gemma":[0.0009940474,0.00016797382,0.00023326601,0.0003862042,0.00020834628,0.00016458277,0.000052632156,0.0024578606,0.000028082415],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.05155536,0.007792765,0.027951181,0.000788441,0.002566256,0.0046992423,0.012230993,0.017905172,0.6267059,0.004152884,0.1801614,0.06349039],"study_design_scores_gemma":[0.06768438,0.036839213,0.025389006,0.0008943787,0.0015812083,0.0035893505,0.0022193484,0.61910844,0.15327686,0.0031524359,0.083903074,0.0023622948],"about_ca_topic_score_codex":0.000025961934,"about_ca_topic_score_gemma":0.000031409825,"teacher_disagreement_score":0.60120326,"about_ca_system_score_codex":0.00022152512,"about_ca_system_score_gemma":0.00080385106,"threshold_uncertainty_score":0.99984354},"labels":[],"label_agreement":null},{"id":"W3035067066","doi":"10.1111/jsap.13135","title":"The World Small Animal Veterinary Association ( <scp>WSAVA</scp> )","year":2020,"lang":"en","type":"article","venue":"Journal of Small Animal Practice","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Guelph; Université de Montréal","funders":"Japan Society of Applied Physics","keywords":"Medicine; Guideline; Audit; Certification; Pharmacovigilance; Quality (philosophy); Family medicine; Pharmacology; Adverse effect; Business; Accounting","score_opus":0.21213819471228318,"score_gpt":0.4196621316412004,"score_spread":0.20752393692891724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3035067066","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93025136,0.001016871,0.00017409159,0.038147487,0.0018123222,0.0004412645,0.00001619407,0.000076717166,0.028063707],"genre_scores_gemma":[0.9831795,0.0006951916,0.0012591019,0.010257668,0.0029236742,0.000014672058,0.0000022861543,0.00004256386,0.0016253227],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99583143,0.0020202014,0.0008844851,0.00026617068,0.00042242685,0.0005752945],"domain_scores_gemma":[0.9900236,0.0067809727,0.001986199,0.00012783665,0.0006503365,0.00043102482],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0048091947,0.000280655,0.00038233743,0.00012004156,0.000785459,0.00019599419,0.0005333778,0.00041263056,0.00010737991],"category_scores_gemma":[0.007875392,0.00023091817,0.0002697197,0.00051313743,0.0000841669,0.0008373087,0.00015274175,0.0037399991,0.0002739222],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0145560205,0.0016681384,0.013037052,0.00025938608,0.0027213248,0.0018106985,0.0058186585,0.0006065716,0.84963876,0.002960796,0.06576383,0.04115875],"study_design_scores_gemma":[0.0014270206,0.0028570495,0.00519958,0.000023392944,0.0004854358,0.000536839,0.0011451303,0.0013676618,0.029507784,0.00014842156,0.95716673,0.00013496327],"about_ca_topic_score_codex":0.000022586053,"about_ca_topic_score_gemma":0.000047577996,"teacher_disagreement_score":0.8914029,"about_ca_system_score_codex":0.00032640435,"about_ca_system_score_gemma":0.00024400759,"threshold_uncertainty_score":0.9985584},"labels":[],"label_agreement":null},{"id":"W3035686784","doi":"10.20944/preprints202006.0122.v1","title":"Synergistic Hepatoprotective Interaction between &amp;alpha;-Tocopherol and Ascorbic Acid on Paracetamol Induced Liver Damage in Rats","year":2020,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Global Health Research","funders":"","keywords":"Ascorbic acid; Chemistry; Antioxidant; Acetaminophen; Lipid peroxidation; Malondialdehyde; alpha-Tocopherol; Internal medicine; Pharmacology; Biochemistry; Endocrinology; Vitamin E; Medicine; Food science","score_opus":0.5088848361175599,"score_gpt":0.49057477365588725,"score_spread":0.018310062461672605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3035686784","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883525,0.0000902267,0.0002211093,0.00086975825,0.0019747943,0.0045133852,0.00011656129,0.0003284709,0.003533221],"genre_scores_gemma":[0.99581563,0.00025713615,0.00007039765,0.0008021662,0.00080207974,0.0017500917,0.00012711145,0.000104180646,0.00027122194],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99334747,0.0025545284,0.0010145026,0.0019298284,0.0004055338,0.0007481159],"domain_scores_gemma":[0.99706674,0.00064236607,0.00074871833,0.0008832385,0.000157629,0.0005012959],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0017290869,0.0008985336,0.001108053,0.0004994975,0.00037160015,0.000062798514,0.0006734741,0.002120906,0.0012326312],"category_scores_gemma":[0.0009169903,0.0010223192,0.00025818901,0.00041938698,0.00020922619,0.00028544205,0.0014827211,0.009266851,0.0025972645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022540786,0.00078187947,0.36465162,0.0010873656,0.00085690134,0.00028229592,0.0063531096,0.001609541,0.60540754,0.00021247944,0.00007172346,0.016431471],"study_design_scores_gemma":[0.0018765948,0.00021793297,0.32983097,0.0005085269,0.00034497914,0.00001528218,0.00015422187,0.0025717719,0.6548225,0.0037659013,0.0047020605,0.0011892106],"about_ca_topic_score_codex":0.0012533589,"about_ca_topic_score_gemma":0.0005080184,"teacher_disagreement_score":0.049415,"about_ca_system_score_codex":0.00070388947,"about_ca_system_score_gemma":0.000261651,"threshold_uncertainty_score":0.9996804},"labels":[],"label_agreement":null},{"id":"W3040613922","doi":"10.1016/j.cgh.2020.06.067","title":"A High Serum Level of Taurocholic Acid Is Correlated With the Severity and Resolution of Drug-induced Liver Injury","year":2020,"lang":"en","type":"article","venue":"Clinical Gastroenterology and Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Natural Science Foundation of China","keywords":"Medicine; Taurocholic acid; Internal medicine; Gastroenterology; Bile acid; Cholestasis; Liver injury; Glycocholic acid; Liver biopsy; Body mass index; Ursodeoxycholic acid; Endocrinology; Biopsy; Cholic acid","score_opus":0.24363089138821153,"score_gpt":0.4166537347490587,"score_spread":0.17302284336084717,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3040613922","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9861685,0.00014183814,0.00045628377,0.012156259,0.0004076841,0.00043095622,0.0001615201,0.000033212174,0.000043764154],"genre_scores_gemma":[0.98606193,0.00045202218,0.00018544332,0.013125261,0.00010188718,0.000024497629,0.000008820882,0.000015232862,0.000024897075],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9966035,0.0016967285,0.0007279109,0.00048138486,0.00009559369,0.00039491526],"domain_scores_gemma":[0.9984588,0.00047287514,0.00049936614,0.00019879291,0.00013712815,0.00023300883],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009335432,0.00024131183,0.00074962707,0.00006789937,0.00020420231,0.0000046407736,0.00021825517,0.00070187694,0.00013488684],"category_scores_gemma":[0.00014087424,0.00018405236,0.00010299882,0.00016014636,0.0014397885,0.00008561956,0.000208688,0.0016394815,0.00001067084],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013710376,0.00047535723,0.9578246,0.00019231696,0.00058027403,0.00003995837,0.002108975,0.000009630558,0.008762245,0.0006365231,0.0024658365,0.013193946],"study_design_scores_gemma":[0.011386563,0.010244538,0.9134369,0.000060607865,0.00107567,0.0005835271,0.0005520037,0.010158088,0.044177298,0.0006783794,0.007181951,0.0004644604],"about_ca_topic_score_codex":0.00012617055,"about_ca_topic_score_gemma":0.00029690913,"teacher_disagreement_score":0.04438765,"about_ca_system_score_codex":0.000012671288,"about_ca_system_score_gemma":0.00006925921,"threshold_uncertainty_score":0.7505438},"labels":[],"label_agreement":null},{"id":"W3042711712","doi":"10.47070/ijapr.v8i7.1433","title":"CRITICAL ANALYSIS OF PURVA KARMA PRIOR TO NASYA W.S.R. SNEHA NASYA","year":2020,"lang":"en","type":"article","venue":"International Journal of Ayurveda and Pharma Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Shared Services Canada","funders":"","keywords":"Karma; Medicine; Context (archaeology); Bioavailability; Pharmacology; Drug","score_opus":0.4429943793380631,"score_gpt":0.5996448003217657,"score_spread":0.15665042098370258,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3042711712","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97164077,0.0005146042,0.0011035225,0.022953726,0.0012734743,0.00027910672,0.00015551843,0.000016682983,0.002062584],"genre_scores_gemma":[0.9957793,0.000562483,0.0003586124,0.0022601173,0.00091619935,0.000011965968,0.000008500214,0.000017051756,0.00008582343],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9960729,0.0012412205,0.0008032436,0.00028244467,0.0011954011,0.0004048074],"domain_scores_gemma":[0.99505943,0.0015662872,0.00021760038,0.00010375884,0.002303297,0.0007496196],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0038342576,0.00017306114,0.00047170246,0.0010565041,0.00019621382,0.000094217816,0.00075469364,0.00021726814,0.0018804253],"category_scores_gemma":[0.0019692485,0.00016088752,0.00027872162,0.0011822,0.00028508427,0.00035430957,0.00026030297,0.0017813308,0.000056820158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0119927395,0.0016022013,0.053996224,0.0002609295,0.010449997,0.0009782023,0.011297108,0.004539113,0.6761059,0.005095231,0.015356551,0.20832582],"study_design_scores_gemma":[0.0068486375,0.0026775429,0.034323085,0.00017225859,0.0016336765,0.0003304999,0.0016671867,0.036884516,0.5368818,0.001896182,0.37590793,0.00077668426],"about_ca_topic_score_codex":0.00006291682,"about_ca_topic_score_gemma":0.000011958866,"teacher_disagreement_score":0.36055136,"about_ca_system_score_codex":0.00012548019,"about_ca_system_score_gemma":0.00023578775,"threshold_uncertainty_score":0.999032},"labels":[],"label_agreement":null},{"id":"W3042872506","doi":"10.1093/jcag/gwaa017","title":"Role of<i>N</i>-Acetylcysteine in the Treatment of Acute Nonacetaminophen, Nonalcoholic and Nonviral Hepatitis: A Meta-analysis","year":2020,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Impact; McMaster University","funders":"","keywords":"Medicine; Internal medicine; Placebo; Meta-analysis; Alcoholic hepatitis; Randomized controlled trial; Odds ratio; Population; Hepatitis; Cirrhosis; Alcoholic liver disease; Pathology","score_opus":0.07703110774305619,"score_gpt":0.3383110643602366,"score_spread":0.2612799566171804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3042872506","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9831738,0.00019736937,0.000016105016,0.015842916,0.00012646188,0.0002641107,0.00026865816,0.0000013195136,0.00010926976],"genre_scores_gemma":[0.9973378,0.00024164136,0.00006871091,0.0022234456,0.00006832719,0.000011000898,0.0000044994986,0.0000058752903,0.00003866671],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99730974,0.0014314813,0.00070240145,0.00010591248,0.00021982448,0.00023062015],"domain_scores_gemma":[0.9979479,0.00019429356,0.0014265341,0.00011115222,0.00018388359,0.00013627076],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011035923,0.0001306143,0.0008623664,0.000247279,0.0000786925,0.0000064300975,0.00026746315,0.00019038869,0.00008919289],"category_scores_gemma":[0.00007710981,0.00008603159,0.0006713002,0.00036834073,0.0000988271,0.00006725966,0.000017095526,0.00037208997,9.2867447e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006199952,0.0002621999,0.92820096,0.000020827163,0.050629105,0.000011804672,0.0050479476,0.0016920083,0.012943828,0.00007470842,0.00018556736,0.00031106587],"study_design_scores_gemma":[0.0088137435,0.0074535003,0.7901893,0.000011613531,0.15453434,0.00012140976,0.0006782537,0.003956429,0.020887954,0.00040066158,0.0127297845,0.00022300782],"about_ca_topic_score_codex":0.0067389207,"about_ca_topic_score_gemma":0.18178959,"teacher_disagreement_score":0.17505068,"about_ca_system_score_codex":0.0002827024,"about_ca_system_score_gemma":0.00014517843,"threshold_uncertainty_score":0.9998753},"labels":[],"label_agreement":null},{"id":"W3045444247","doi":"10.5539/jfr.v9n5p14","title":"Efficacy of the Aqueous Extracts of Justicia Galeopsis Leaves on the Improvement of Hematological Parameters in Anemic Rats","year":2020,"lang":"en","type":"article","venue":"Journal of Food Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Hematocrit; Hemoglobin; Anemia; Distilled water; Phenylhydrazine; Aqueous extract; Kidney; Medicine; Body weight; Spleen; Traditional medicine; Chemistry; Animal science; Pharmacology; Internal medicine; Biology; Chromatography","score_opus":0.4528737338675817,"score_gpt":0.4916278189743958,"score_spread":0.03875408510681411,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3045444247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99322784,0.0002960003,0.000009653397,0.005009499,0.00024743937,0.00059261394,0.00000957832,0.0000027108274,0.0006046894],"genre_scores_gemma":[0.999338,0.00022519837,0.000034357232,0.00029363614,0.000078982855,0.000008921244,2.1335794e-7,0.00000764159,0.0000130587405],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966876,0.001513752,0.0007599765,0.00013097303,0.00061229954,0.00029543115],"domain_scores_gemma":[0.9960588,0.0028316535,0.0005454572,0.00015865135,0.00028888325,0.000116520416],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0032702226,0.000111388385,0.00037556994,0.0001649604,0.00011088945,0.0000072937037,0.0005533442,0.00023799133,0.00008853121],"category_scores_gemma":[0.0022252474,0.0000624425,0.00019468494,0.00056329125,0.0004206157,0.000047453228,0.000109805114,0.002383067,0.0000031526654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0031526505,0.0010625467,0.0020169811,0.00029155173,0.00020979649,0.00003150969,0.0023040022,0.0022111633,0.9733194,0.00070845924,0.00056040514,0.014131502],"study_design_scores_gemma":[0.0011250074,0.0026748534,0.0046205632,0.00013884253,0.000045652607,0.000023697046,0.0005676905,0.00038200535,0.9893615,0.00074100675,0.00026306006,0.000056079432],"about_ca_topic_score_codex":0.000015655898,"about_ca_topic_score_gemma":0.000010389851,"teacher_disagreement_score":0.01604211,"about_ca_system_score_codex":0.000060993025,"about_ca_system_score_gemma":0.00021806241,"threshold_uncertainty_score":0.99991846},"labels":[],"label_agreement":null},{"id":"W3045798300","doi":"10.1111/jvp.12893","title":"Pharmacokinetics of acetaminophen after intravenous and oral administration in fasted and fed Labrador Retriever dogs","year":2020,"lang":"en","type":"article","venue":"Journal of Veterinary Pharmacology and Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Università di Pisa","keywords":"Acetaminophen; Pharmacokinetics; Bioavailability; Labrador Retriever; Plasma concentration; Medicine; Oral administration; Anesthesia; Pharmacology; Surgery","score_opus":0.12322106831309435,"score_gpt":0.40521269319657205,"score_spread":0.28199162488347773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3045798300","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99404943,0.002279908,0.000097841206,0.0024992991,0.0006185548,0.00035352958,0.000030414041,0.0000129058735,0.000058140988],"genre_scores_gemma":[0.9905897,0.0050906534,0.00034318358,0.0037000047,0.00022564536,0.000009554595,0.000002394814,0.000019631389,0.00001924425],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99802667,0.00069806376,0.00065717427,0.0002211949,0.00012919084,0.0002677312],"domain_scores_gemma":[0.9989209,0.00026556433,0.0004071352,0.00005223707,0.000114095266,0.00024004097],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068637624,0.00023872634,0.0004890342,0.00016056467,0.000094660434,0.000018624625,0.00012273813,0.00036724476,0.00015708193],"category_scores_gemma":[0.000021230348,0.00022709325,0.00005367307,0.00021583417,0.0003506819,0.00023887525,0.000088912406,0.0011263844,0.0000015278324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.019293088,0.0005701669,0.023412693,0.00039784363,0.0005936098,0.000712797,0.005906118,0.000032943655,0.8725349,0.000051954277,0.000068763,0.076425165],"study_design_scores_gemma":[0.04268399,0.03880915,0.20919634,0.00022644547,0.003512805,0.007308923,0.0016086475,0.019625528,0.52836555,0.0015253895,0.1453888,0.0017484395],"about_ca_topic_score_codex":0.000004807916,"about_ca_topic_score_gemma":0.00000349423,"teacher_disagreement_score":0.34416932,"about_ca_system_score_codex":0.000030419273,"about_ca_system_score_gemma":0.00008259124,"threshold_uncertainty_score":0.92605937},"labels":[],"label_agreement":null},{"id":"W3046586005","doi":"10.3138/canlivj-2020-0009","title":"Rituximab-induced autoimmune hepatitis: A case study and literature review","year":2020,"lang":"en","type":"article","venue":"Canadian Liver Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Rituximab; Medicine; CD20; Autoimmune hepatitis; Lymphoma; Immunology; Monoclonal antibody; Monoclonal; Hepatitis; Liver injury; Hepatitis B; Antibody; Internal medicine","score_opus":0.13728859479452774,"score_gpt":0.39127726065089036,"score_spread":0.2539886658563626,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3046586005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94249284,0.046910472,0.000015695952,0.0076653245,0.0009483711,0.0010113722,0.00007362943,0.00004965757,0.00083264185],"genre_scores_gemma":[0.9609672,0.018064216,0.000049479695,0.020160835,0.00058180845,0.000028676943,0.000005505356,0.000022905615,0.000119362485],"study_design_codex":"case_report","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979088,0.000860176,0.0003732943,0.00027738206,0.00013076818,0.00044960607],"domain_scores_gemma":[0.99804026,0.000068298825,0.00014420562,0.00012414396,0.00016380526,0.0014593087],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00079538755,0.00023255458,0.000368156,0.00016002009,0.0009239158,0.00013238587,0.00018378317,0.00027641625,0.0009870906],"category_scores_gemma":[0.00016278277,0.00022940086,0.00009131704,0.00040239622,0.000051638646,0.0003115466,0.000039321636,0.0024904332,0.0001186255],"study_design_candidate":"case_report","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018870101,0.0006767859,0.027920863,0.0019177105,0.0010680575,0.46605223,0.04755994,0.0000128557895,0.0033960291,0.0002561199,0.043317113,0.4076336],"study_design_scores_gemma":[0.011550269,0.002665504,0.012793826,0.0027486186,0.0017241251,0.31055838,0.0048817014,0.0059125796,0.0010309004,0.00019119057,0.64396,0.0019829208],"about_ca_topic_score_codex":0.012596158,"about_ca_topic_score_gemma":0.029405262,"teacher_disagreement_score":0.60064286,"about_ca_system_score_codex":0.0001854532,"about_ca_system_score_gemma":0.00043388738,"threshold_uncertainty_score":0.99992615},"labels":[],"label_agreement":null},{"id":"W3053144365","doi":"10.1093/pch/pxaa068.098","title":"99 Newly approved IV acetaminophen in Canada: Should we switch from oral to IV? A systematic review","year":2020,"lang":"en","type":"review","venue":"Paediatrics & Child Health","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Western University; Université de Montréal","funders":"","keywords":"Acetaminophen; Medicine; Placebo; Analgesic; Pharmacokinetics; Pharmacodynamics; Population; Anesthesia; Bioavailability; Pharmacology; Alternative medicine","score_opus":0.18105146139487904,"score_gpt":0.425322646814117,"score_spread":0.24427118541923798,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3053144365","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000013557653,0.966237,0.00008222435,0.014403015,0.0027748812,0.014708384,0.001202974,0.00014019317,0.00043779006],"genre_scores_gemma":[0.000116411546,0.9625418,0.00023298681,0.03329447,0.0013193521,0.0017930623,0.0004642394,0.00015303025,0.00008464654],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.98806036,0.005028639,0.0033164993,0.0013833258,0.00076447363,0.0014467058],"domain_scores_gemma":[0.99418855,0.0014687928,0.0018779181,0.00082240114,0.0001151667,0.0015271469],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0033315152,0.0012123939,0.0068848007,0.00046657046,0.00046055924,0.00004967794,0.0012466159,0.0011716557,0.00022107257],"category_scores_gemma":[0.0010379254,0.0010876501,0.00064146187,0.0025796527,0.000034189197,0.00011825813,0.00035387638,0.0062175044,0.00057225575],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":true,"about_ca_system_consensus":true,"study_design_scores_codex":[0.000027451897,0.00013929876,0.00005232386,0.7068815,0.0003060734,0.000087453765,0.00044402783,0.00001204167,2.0113005e-7,0.000055145076,0.016451996,0.2755425],"study_design_scores_gemma":[0.000659069,0.00010609992,0.000012397247,0.110840134,0.0022818174,0.000037262653,0.000052564774,0.00015389378,6.8930075e-7,0.000048473,0.8849353,0.000872304],"about_ca_topic_score_codex":0.31624597,"about_ca_topic_score_gemma":0.456123,"teacher_disagreement_score":0.8684833,"about_ca_system_score_codex":0.0048715672,"about_ca_system_score_gemma":0.011078537,"threshold_uncertainty_score":0.99915737},"labels":[],"label_agreement":null},{"id":"W3061543625","doi":"10.21037/atm-2020-ubih-05","title":"Mechanism of idiosyncratic drug induced liver injury (DILI): unresolved basic issues","year":2021,"lang":"en","type":"review","venue":"Annals of Translational Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Immune system; Mechanism (biology); Causality (physics); Immunology; Drug; Innate immune system; Medicine; Bioinformatics; Biology; Pharmacology","score_opus":0.43176895699514267,"score_gpt":0.5290119358740372,"score_spread":0.09724297887889449,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3061543625","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007265378,0.9923933,0.00014409117,0.0023445787,0.0014336155,0.0012997224,0.0003307585,0.00004584626,0.0012815509],"genre_scores_gemma":[0.015086941,0.98236644,0.00013083014,0.0006667514,0.00079700025,0.000106839,0.00042916855,0.000057805977,0.00035823404],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9951087,0.0016821441,0.0016744722,0.0005145055,0.000629345,0.0003907967],"domain_scores_gemma":[0.99666667,0.0013042762,0.00092283555,0.00036150607,0.00052311324,0.00022157979],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0022556193,0.0005646671,0.0025750084,0.00054834783,0.0001491753,0.000005576718,0.00042281355,0.0010072562,0.0026870442],"category_scores_gemma":[0.00029976424,0.000487633,0.00063729123,0.0007675672,0.000286976,0.0001488137,0.000045407975,0.0015257627,0.000038514998],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014657233,0.00043421204,0.000008844477,0.018228373,0.0014191557,0.000038406917,0.0013282222,0.00000871138,0.0019628217,0.014686992,0.0035363573,0.95820135],"study_design_scores_gemma":[0.0008586279,0.0004117344,0.000013252092,0.013340503,0.0018925453,0.000034585366,0.00006692301,0.00018957426,0.017199758,0.0039576464,0.96151143,0.00052341766],"about_ca_topic_score_codex":0.00016730651,"about_ca_topic_score_gemma":0.000042288226,"teacher_disagreement_score":0.9579751,"about_ca_system_score_codex":0.00002429048,"about_ca_system_score_gemma":0.0005108061,"threshold_uncertainty_score":0.9997575},"labels":[],"label_agreement":null},{"id":"W30790198","doi":"10.1007/s12630-019-01322-x","title":"Hematological alterations in broiler chicks during different seasons supplemented with herbal formulations","year":2008,"lang":"en","type":"article","venue":"Veterinary World","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University Hospital Foundation; Canadian Donation and Transplantation Research Program","keywords":"Broiler; Winter season; Biology; Summer season; Veterinary medicine; Animal science; Wet season; Traditional medicine; Medicine; Ecology; Geography","score_opus":0.175549609155884,"score_gpt":0.4047572852073636,"score_spread":0.2292076760514796,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W30790198","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932074,0.00003823395,0.00027138734,0.0010264855,0.0002872154,0.0006475566,0.000058564132,0.00014467335,0.004318474],"genre_scores_gemma":[0.9961956,0.000032061816,0.0003197908,0.00029889212,0.00012054067,0.00032171552,0.00008203884,0.00002109806,0.0026082234],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99846154,0.00031799352,0.00029769537,0.00032482023,0.00014137679,0.0004565773],"domain_scores_gemma":[0.99940443,0.00013346701,0.000083990766,0.00018182823,0.00003341747,0.00016285207],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00013241963,0.00023695064,0.00025609616,0.00024586602,0.00068862224,0.00001786419,0.00013742637,0.00015066644,0.0015591595],"category_scores_gemma":[0.000014482429,0.00020383789,0.00007207253,0.00042866683,0.00012144307,0.00021245272,0.000078976176,0.00081638544,0.00006128689],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0051653916,0.004212581,0.7798921,0.00031156623,0.00041546658,0.0028431886,0.004777505,0.0053801564,0.1861492,0.006510676,0.0023099678,0.002032205],"study_design_scores_gemma":[0.011130998,0.0016664056,0.81341255,0.00021323272,0.00012501939,0.003989954,0.00023271551,0.012936302,0.07743496,0.0008202224,0.07656357,0.0014740727],"about_ca_topic_score_codex":0.000029620482,"about_ca_topic_score_gemma":0.00058327836,"teacher_disagreement_score":0.108714245,"about_ca_system_score_codex":0.00012976726,"about_ca_system_score_gemma":0.000038732007,"threshold_uncertainty_score":0.9993535},"labels":[],"label_agreement":null},{"id":"W3083890406","doi":"10.1016/j.cgh.2020.09.016","title":"Clinical and Neurologic Outcomes in Acetaminophen-Induced Acute Liver Failure: A 21-Year Multicenter Cohort Study","year":2020,"lang":"en","type":"article","venue":"Clinical Gastroenterology and Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Baylor University Medical Center; University of Alberta; University of California, San Diego; University of Oregon; Genentech; University of Pittsburgh; Northwestern University; University of Washington; Emory University; National Institutes of Health; Ohio State University; Virginia Commonwealth University; Yale University; University of Pennsylvania; Massachusetts General Hospital; University of California, Los Angeles; University of South Carolina; National Institute of Diabetes and Digestive and Kidney Diseases; Baylor University; Merck","keywords":"Medicine; Internal medicine; Cohort; Comorbidity; Delirium; Cohort study; Retrospective cohort study; Odds ratio; Intensive care medicine","score_opus":0.17148889202577947,"score_gpt":0.45129823262393753,"score_spread":0.2798093405981581,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3083890406","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98608553,0.00005547051,0.00006773197,0.010304515,0.001502522,0.0017354934,0.000026797756,0.00012656905,0.0000953714],"genre_scores_gemma":[0.9695374,0.00057302957,0.00022477125,0.029159412,0.00027259655,0.00016406988,0.0000106618045,0.000031644406,0.000026434871],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9902853,0.0056555616,0.0016872684,0.0013757532,0.00013398007,0.0008621332],"domain_scores_gemma":[0.997111,0.0014425323,0.00038112156,0.00031780568,0.00007602706,0.00067151187],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0026218551,0.00048072846,0.001673813,0.00014422642,0.00023635985,0.000024529287,0.0003753482,0.0014137658,0.00024638968],"category_scores_gemma":[0.0007345235,0.00043451833,0.0002373238,0.00015015031,0.0011285772,0.00015957649,0.00055972824,0.0038930366,0.00014020223],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004852351,0.0017897355,0.9886739,0.000029178842,0.00062365667,0.00071759627,0.00038477223,0.0000020575844,0.00015589374,0.000082131744,0.00022021901,0.002468459],"study_design_scores_gemma":[0.011355737,0.006259448,0.97689545,0.0000038434737,0.0005025667,0.00011330021,0.0001749642,0.0027004308,0.000025511097,0.00011785125,0.0016048154,0.00024610115],"about_ca_topic_score_codex":0.000048602327,"about_ca_topic_score_gemma":0.00077893736,"teacher_disagreement_score":0.018854896,"about_ca_system_score_codex":0.000020978883,"about_ca_system_score_gemma":0.000053152595,"threshold_uncertainty_score":0.9998826},"labels":[],"label_agreement":null},{"id":"W3103844081","doi":"10.1111/bcp.14631","title":"<i>N</i>‐acetylcysteine for acetaminophen toxicity: The one‐bag regimen","year":2020,"lang":"en","type":"letter","venue":"British Journal of Clinical Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Regimen; Medicine; Acetylcysteine; Bolus (digestion); Dosing; Acetaminophen; Antidote; Toxicity; Pharmacology; Surgery; Internal medicine; Chemistry","score_opus":0.29836363702356145,"score_gpt":0.4865365769098365,"score_spread":0.18817293988627504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3103844081","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016145537,0.003913205,0.0008059689,0.93840116,0.034470182,0.0032517887,0.00063103327,0.00013527359,0.0022458646],"genre_scores_gemma":[0.015552047,0.006233317,0.00073000253,0.89150375,0.082028076,0.00023798557,0.000116049065,0.00017185266,0.003426904],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.98623717,0.00670229,0.0041803387,0.00089558493,0.0007433335,0.0012412794],"domain_scores_gemma":[0.9846007,0.009254955,0.004171112,0.0003400228,0.0009981556,0.00063504453],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.007592682,0.00071209297,0.0027319577,0.00020165014,0.00086280983,0.0001464033,0.0021894216,0.003971466,0.0019009648],"category_scores_gemma":[0.0024960658,0.00068834494,0.001964274,0.00039718306,0.0010919212,0.0003058573,0.00034516014,0.022622146,0.0002155253],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016907093,0.00054894807,0.00004620432,0.00041691007,0.0026592382,0.0030957162,0.00011201204,0.00009216558,0.003033583,0.000015888258,0.91817635,0.07011225],"study_design_scores_gemma":[0.009144158,0.0017606443,0.000056326844,0.00018606006,0.0028531158,0.002295789,0.000029125977,0.0005057365,0.0065352516,0.0017194769,0.9742457,0.0006686093],"about_ca_topic_score_codex":0.0000314192,"about_ca_topic_score_gemma":0.000017267468,"teacher_disagreement_score":0.06944364,"about_ca_system_score_codex":0.00020359065,"about_ca_system_score_gemma":0.0010267638,"threshold_uncertainty_score":0.9995568},"labels":[],"label_agreement":null},{"id":"W3113759994","doi":"10.14740/jmc3611","title":"Use of N-Acetylcysteine in Amphetamine-Induced Acute Liver Failure","year":2020,"lang":"en","type":"article","venue":"Journal of Medical Cases","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Acetylcysteine; Recreational Drug; Amphetamine; Drug; Recreational use; Ingestion; Ecstasy; Liver failure; Complication; Pharmacology; Anesthesia; Surgery; Internal medicine; Recreation; Psychiatry","score_opus":0.29338950447289575,"score_gpt":0.4393233092853776,"score_spread":0.14593380481248186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3113759994","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9853311,0.00029038574,0.00018899118,0.013305352,0.00060973293,0.00017729799,0.000021198846,0.000014207545,0.00006173701],"genre_scores_gemma":[0.99478793,0.00065151823,0.00023916172,0.0036354866,0.0006374475,0.000003813958,0.000002543333,0.0000130618555,0.00002903772],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976286,0.0005862858,0.0007734092,0.00013932736,0.00063234405,0.00023998007],"domain_scores_gemma":[0.99802953,0.00076559506,0.00044687634,0.00008060236,0.00015661148,0.0005207678],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010586816,0.00015472836,0.00048257218,0.00014721252,0.000051695293,0.000012696109,0.0002822546,0.00053548784,0.0013388837],"category_scores_gemma":[0.002005882,0.00012709068,0.00017048002,0.00034769197,0.00011094036,0.0002689238,0.00007716346,0.0017367615,0.000022832597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0067062657,0.002423182,0.019699411,0.0009040315,0.0014881508,0.03845759,0.007209932,0.0006987057,0.7162042,0.0007461176,0.03572111,0.16974132],"study_design_scores_gemma":[0.012913099,0.0051787514,0.0043346374,0.0006234028,0.00083924265,0.00879947,0.0010668,0.014162333,0.6211865,0.00010849084,0.3300816,0.00070565223],"about_ca_topic_score_codex":0.000077573866,"about_ca_topic_score_gemma":0.00010729062,"teacher_disagreement_score":0.29436052,"about_ca_system_score_codex":0.000052527477,"about_ca_system_score_gemma":0.00025337347,"threshold_uncertainty_score":0.999574},"labels":[],"label_agreement":null},{"id":"W3122938643","doi":"10.1111/bcp.14755","title":"Predicting mortality from acetaminophen poisoning shortly after hospital presentation","year":2021,"lang":"en","type":"article","venue":"British Journal of Clinical Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Western University; University of Toronto; Dalhousie University; University of British Columbia; Centre for Drug Research and Development; Alberta Children's Hospital; South Health Campus; University of Calgary; University of Alberta; Queen's University; Alberta Health Services","funders":"Research Services, University of Calgary; Alberta Innovates; American College of Medical Toxicology; Alberta Health Services","keywords":"Medicine; Acetaminophen; Ingestion; Case fatality rate; Hepatic encephalopathy; Internal medicine; Anesthesia; Emergency medicine; Epidemiology","score_opus":0.17656163433897298,"score_gpt":0.5046679569565375,"score_spread":0.32810632261756456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3122938643","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97554076,0.002491414,0.0004145048,0.0011584503,0.01863487,0.0003449206,0.0001444887,0.000055866847,0.001214741],"genre_scores_gemma":[0.9861758,0.0021806117,0.000651534,0.003736777,0.006913623,0.000036366953,0.000036205573,0.00003561948,0.00023348282],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99303544,0.0033099519,0.0022319267,0.00048827726,0.00040285414,0.0005315644],"domain_scores_gemma":[0.9954749,0.0019374202,0.0011883631,0.00014410923,0.00071393885,0.00054129364],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0032838543,0.00024834333,0.0008651777,0.0000834606,0.00029249088,0.000087355984,0.00036529178,0.0008235679,0.004513846],"category_scores_gemma":[0.0015768562,0.0003036718,0.00056216837,0.000255643,0.00031371904,0.0005970585,0.00018294014,0.0037883548,0.00006297482],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013192896,0.0024126256,0.7870097,0.000066101675,0.0022084706,0.010333373,0.000640112,0.00064187415,0.018359568,0.000014431102,0.010517598,0.16647682],"study_design_scores_gemma":[0.009201739,0.00066977186,0.8862679,0.00017546753,0.0016687189,0.0014637263,0.0004257605,0.0030689822,0.049772426,0.0016265187,0.045066047,0.0005929675],"about_ca_topic_score_codex":0.00016669338,"about_ca_topic_score_gemma":0.00015684115,"teacher_disagreement_score":0.16588385,"about_ca_system_score_codex":0.000093022674,"about_ca_system_score_gemma":0.0004569023,"threshold_uncertainty_score":0.9999415},"labels":[],"label_agreement":null},{"id":"W3124785042","doi":"","title":"For Peace and Pain: The Medical Legitimization of Afghanistan’s Poppy Crop","year":2011,"lang":"en","type":"article","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Afghan; Opium; Poppy; Status quo; Politics; Political science; Medicine; Development economics; Public administration; Law; Economic growth; Geography; Economics","score_opus":0.24838035291852134,"score_gpt":0.4245112762660251,"score_spread":0.17613092334750374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3124785042","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5292074,0.000940152,0.28831282,0.015178029,0.0031850978,0.0049956697,0.00011556207,0.0003744071,0.15769085],"genre_scores_gemma":[0.99440765,0.00018546855,0.00077276805,0.0029141253,0.00013141056,0.000104786064,0.0000075360786,0.000011893063,0.0014643677],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99890107,0.0004249898,0.00022220408,0.00015145338,0.00011701166,0.00018325851],"domain_scores_gemma":[0.9991944,0.0004162942,0.00008997963,0.000102172045,0.00008853762,0.00010865645],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0021401145,0.00009879792,0.00012990611,0.000039143986,0.00024683066,0.0000074981613,0.00013824172,0.0002951293,0.001763915],"category_scores_gemma":[0.00030723802,0.0000700319,0.000048789338,0.000089680856,0.00020558572,0.000073110954,0.00003621647,0.00030125762,0.0000080393365],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004171959,0.0021638838,0.01610159,0.001094115,0.00086952373,0.00003907976,0.019613573,0.00014275184,0.044205897,0.38898954,0.057426848,0.46518123],"study_design_scores_gemma":[0.004012587,0.00096909556,0.0024210964,0.000048626465,0.00024144542,0.00008596935,0.0014986645,0.06337313,0.3234807,0.011461915,0.5918782,0.00052859786],"about_ca_topic_score_codex":0.00008928072,"about_ca_topic_score_gemma":0.00011458523,"teacher_disagreement_score":0.53445137,"about_ca_system_score_codex":0.000015416375,"about_ca_system_score_gemma":0.00006221997,"threshold_uncertainty_score":0.9991486},"labels":[],"label_agreement":null},{"id":"W3125315716","doi":"10.1016/j.microc.2021.105964","title":"Green analytical method for the determination of sofosbuvir, ledipasvir, ribavirin and complex silymarin flavonoids simultaneously in biological fluids","year":2021,"lang":"en","type":"article","venue":"Microchemical Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Ledipasvir; Sofosbuvir; Formic acid; Ribavirin; Cirrhosis; Chemistry; Chromatography; Hepatitis C virus; Medicine; Gastroenterology; Virus; Virology","score_opus":0.18057674303548882,"score_gpt":0.45683432052214196,"score_spread":0.27625757748665314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3125315716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93780875,0.0005353438,0.058155596,0.002571721,0.00031094812,0.00037455163,0.00003846962,0.000019066332,0.00018555082],"genre_scores_gemma":[0.98469347,0.00035189305,0.0131348055,0.0012002921,0.00036382294,0.000026808684,0.000023036959,0.000015803525,0.00019006997],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997991,0.0006363672,0.0005854233,0.00028458907,0.00012909822,0.00037352237],"domain_scores_gemma":[0.9970221,0.0023426665,0.00015270295,0.00011592769,0.00020457477,0.0001620435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015613945,0.00018897816,0.0003682855,0.000092739094,0.0002575815,0.000034372293,0.00022892744,0.0005019303,0.0002410643],"category_scores_gemma":[0.00060197274,0.00014507637,0.00016416005,0.00023462977,0.0002550461,0.00007059498,0.00013065309,0.0012804852,0.000004250468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038289113,0.00020778945,0.0024097504,0.000037133497,0.000060677852,0.000049883296,0.00024784714,0.000046593286,0.86510617,0.00016476666,0.00021983731,0.13106664],"study_design_scores_gemma":[0.0030682688,0.00022784017,0.002744417,0.00003383717,0.00017632554,0.0013678295,0.00026957688,0.14201932,0.811316,0.0038756083,0.03459789,0.0003030592],"about_ca_topic_score_codex":0.00002940206,"about_ca_topic_score_gemma":0.000040972798,"teacher_disagreement_score":0.14197274,"about_ca_system_score_codex":0.00009765806,"about_ca_system_score_gemma":0.00009549229,"threshold_uncertainty_score":0.59160423},"labels":[],"label_agreement":null},{"id":"W3126315721","doi":"10.1002/hep4.1663","title":"Collaboration Is Needed to Translate Pharmacology Data Into Better Health Outcomes in Chronic Liver Disease","year":2021,"lang":"en","type":"letter","venue":"Hepatology Communications","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Health Innovation, Investment and Research Office","keywords":"Medicine; Clinical pharmacology; Informatics; Pharmacology; Political science","score_opus":0.2817063238075705,"score_gpt":0.5055172958126591,"score_spread":0.22381097200508865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3126315721","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.014038016,0.010437463,0.00027679728,0.9677382,0.002426001,0.0028418514,0.0016902814,0.00020307166,0.00034831985],"genre_scores_gemma":[0.06862014,0.009570311,0.0013653686,0.90807194,0.0009352377,0.0014348153,0.009151936,0.00011298579,0.0007373009],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.98979884,0.00623332,0.0013265302,0.0012881459,0.0002905736,0.0010625774],"domain_scores_gemma":[0.9934034,0.0012891002,0.00053881825,0.004051261,0.00027714323,0.0004403021],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0010626969,0.00071250135,0.0012957116,0.00082765194,0.0010271713,0.000080813115,0.0035813358,0.002171289,0.0014553784],"category_scores_gemma":[0.00014707596,0.0008281023,0.0002001284,0.0012358029,0.0005322644,0.00041770464,0.0015320602,0.0074871387,0.0006650393],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010639261,0.00046281883,0.0034739298,0.00044430507,0.0005205118,0.00030413215,0.004048779,0.00005524679,0.0009758079,0.00009011346,0.9783159,0.011202049],"study_design_scores_gemma":[0.0014399049,0.00009979881,0.0004185329,0.00008072501,0.00034867926,0.00002310833,0.00010972359,0.011554497,0.0006023549,0.0004294184,0.98420507,0.0006882154],"about_ca_topic_score_codex":0.0029523904,"about_ca_topic_score_gemma":0.016511073,"teacher_disagreement_score":0.059666287,"about_ca_system_score_codex":0.0014418202,"about_ca_system_score_gemma":0.0031876476,"threshold_uncertainty_score":0.9994574},"labels":[],"label_agreement":null},{"id":"W3129527788","doi":"10.1139/cjpp-2021-0008","title":"Quercetin modulates NRF2 and NF-κB/TLR-4 pathways to protect against isoniazid- and rifampicin-induced hepatotoxicity in vivo","year":2021,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Pharmacology; Quercetin; Isoniazid; Aspartate transaminase; Liver injury; Alanine transaminase; Medicine; Rifampicin; Liver function; Oxidative stress; Alkaline phosphatase; Immunology; Antioxidant; Chemistry; Internal medicine; Biochemistry; Pathology; Tuberculosis; Enzyme","score_opus":0.07435086531060411,"score_gpt":0.35216275480560283,"score_spread":0.2778118894949987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3129527788","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932169,0.0013762362,0.000015322601,0.0027134186,0.0014912488,0.00065445655,0.00008549453,0.000018099681,0.00042886278],"genre_scores_gemma":[0.9911275,0.0008268269,0.00014713855,0.0072937584,0.00044649435,0.000051426698,0.0000051704283,0.000029712388,0.000071966504],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963613,0.0015193678,0.0006744731,0.0005408633,0.000092249735,0.00081173837],"domain_scores_gemma":[0.9976873,0.00043257486,0.00028192793,0.00013705203,0.00023804102,0.0012231375],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010984112,0.00038133658,0.00077483995,0.0005358412,0.0005000032,0.000033193857,0.00020687834,0.00077769835,0.0008216731],"category_scores_gemma":[0.00020355315,0.0003911039,0.00008985527,0.00038895354,0.00038370065,0.00020714862,0.00009807977,0.0019397966,0.00001133492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003677735,0.00012395678,0.011012598,0.00015844042,0.0001654068,0.00054007705,0.0023482803,0.0002370435,0.97809565,0.00025177273,0.00057617715,0.0061228243],"study_design_scores_gemma":[0.0031708493,0.00076114916,0.016247233,0.00007364581,0.000121600686,0.00067349727,0.00038394204,0.00081629463,0.9580174,0.0025773968,0.016664645,0.00049235765],"about_ca_topic_score_codex":0.00097421213,"about_ca_topic_score_gemma":0.0072336914,"teacher_disagreement_score":0.02007826,"about_ca_system_score_codex":0.00016410374,"about_ca_system_score_gemma":0.00087772805,"threshold_uncertainty_score":0.9998541},"labels":[],"label_agreement":null},{"id":"W3131444297","doi":"10.1016/j.transci.2021.103094","title":"Symmetrical peripheral gangrene in critical illness","year":2021,"lang":"en","type":"review","venue":"Transfusion and Apheresis Science","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; Hamilton General Hospital; Hamilton Health Sciences; McMaster University; Hamilton Regional Laboratory Medicine Program","funders":"","keywords":"Medicine; Shock (circulatory); Disseminated intravascular coagulation; Anticoagulant; Gangrene; Liver disease; Septic shock; Immunology; Sepsis; Internal medicine; Gastroenterology; Intensive care medicine; Surgery","score_opus":0.27428637590730237,"score_gpt":0.5300207840305374,"score_spread":0.25573440812323506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3131444297","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0031066132,0.99009895,0.00013223752,0.0002321855,0.0015201484,0.00067138736,0.000041158935,0.00006399828,0.0041333176],"genre_scores_gemma":[0.008052033,0.99097586,0.00013333854,0.0002831277,0.00015326812,0.00011416809,0.000008339108,0.000025448178,0.00025441544],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964801,0.0009195587,0.0005876972,0.000926484,0.00039896675,0.00068717793],"domain_scores_gemma":[0.9984397,0.0007210224,0.0000781107,0.00023803381,0.000098020006,0.00042509494],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0017604457,0.00040465035,0.0011247097,0.0005127252,0.00074944476,0.000120925935,0.00044858432,0.00081550487,0.0016192999],"category_scores_gemma":[0.0004059035,0.00034663585,0.00024757377,0.0027914778,0.0010637783,0.00024090908,0.00011708955,0.0017549722,0.00003999574],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015985339,0.00021621322,0.000030870582,0.0019172523,0.000012960913,0.000091762326,0.00026498162,0.000002049304,0.00027643767,0.0020025768,0.00006151386,0.9951074],"study_design_scores_gemma":[0.00046743435,0.00006463777,0.000046979305,0.0020720419,0.00021065213,0.00015727313,0.00015881853,0.00026143657,0.00053257594,0.00012155124,0.9953302,0.00057641265],"about_ca_topic_score_codex":0.00010762269,"about_ca_topic_score_gemma":0.00013424466,"teacher_disagreement_score":0.99526864,"about_ca_system_score_codex":0.00018502884,"about_ca_system_score_gemma":0.00057465147,"threshold_uncertainty_score":0.99989855},"labels":[],"label_agreement":null},{"id":"W3133576030","doi":"10.1002/hep.31783","title":"Prognostic Value of the 13C‐Methacetin Breath Test in Adults with Acute Liver Failure and Non‐acetaminophen Acute Liver Injury","year":2021,"lang":"en","type":"article","venue":"Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Valeant Pharmaceuticals International; Alexion Pharmaceuticals; National Institute of Diabetes and Digestive and Kidney Diseases; University of Arkansas; Gilead Sciences","keywords":"Medicine; Internal medicine; Breath test; Acetaminophen; Gastroenterology; Receiver operating characteristic; Prospective cohort study; Liver transplantation; Liver disease; Cohort; Anesthesia; Transplantation","score_opus":0.027324472821784136,"score_gpt":0.323514199525452,"score_spread":0.2961897267036679,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133576030","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953317,0.00044075467,0.00006240965,0.0016750441,0.00041648402,0.0009686635,0.0001477855,0.000045162564,0.0009120116],"genre_scores_gemma":[0.9963641,0.001066815,0.000638943,0.001218109,0.000077695346,0.0001587519,0.0000214617,0.00003165763,0.00042242554],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974026,0.00095248246,0.00040614547,0.0005475391,0.00016587204,0.0005253253],"domain_scores_gemma":[0.99845684,0.0006561022,0.00023362791,0.00034032483,0.0001714876,0.00014163856],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004130312,0.00031879387,0.0005308988,0.00013560445,0.00022100372,0.000014767866,0.00026796633,0.000713242,0.00026238107],"category_scores_gemma":[0.00015652864,0.00024821117,0.00009395973,0.0005615641,0.00048310225,0.0001345928,0.00025356648,0.0013395728,0.00004473105],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010803896,0.00076115935,0.9467125,0.00034247027,0.0005307421,0.00171038,0.0033612105,0.000022114255,0.036981054,0.0007593568,0.0008350347,0.0069036153],"study_design_scores_gemma":[0.009719094,0.001875757,0.37842008,0.0005985432,0.002225482,0.0062943017,0.0006745666,0.024749244,0.55323863,0.000865844,0.020002749,0.0013356745],"about_ca_topic_score_codex":0.00026109946,"about_ca_topic_score_gemma":0.0013174841,"teacher_disagreement_score":0.5682924,"about_ca_system_score_codex":0.000072640636,"about_ca_system_score_gemma":0.0003059641,"threshold_uncertainty_score":0.999997},"labels":[],"label_agreement":null},{"id":"W3134486170","doi":"10.1055/s-0041-1723030","title":"Assessing Toxicity in Drug Trials in Liver Disease","year":2021,"lang":"en","type":"article","venue":"Seminars in Liver Disease","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"","keywords":"Drug; Clinical trial; Medicine; Intensive care medicine; Liver injury; Drug trial; Liver toxicity; Drug toxicity; Liver disease; Pharmacology; Hepatitis; Liver function; Toxicity; Disease; Drug development; Internal medicine","score_opus":0.19286304812672136,"score_gpt":0.4564016694823199,"score_spread":0.2635386213555986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3134486170","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98735917,0.0074160784,0.000037662987,0.00083971955,0.0011678478,0.000984917,0.00013959654,0.000068950736,0.0019860505],"genre_scores_gemma":[0.9937107,0.003026189,0.00015828584,0.0017454928,0.00027909523,0.00024365669,0.0000810821,0.00003428962,0.0007212158],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99211854,0.0051605366,0.00095125864,0.00075792754,0.00030115177,0.0007106013],"domain_scores_gemma":[0.9970929,0.0015532356,0.0002378106,0.00037085146,0.000076253826,0.000668943],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0044177948,0.00036184565,0.0006982769,0.00045779892,0.00018062371,0.000096427335,0.00028857664,0.00033686325,0.001417579],"category_scores_gemma":[0.002426661,0.00040841624,0.0002574305,0.00092871726,0.00016904916,0.00074312044,0.00020847736,0.0014935969,0.000121411824],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040583615,0.0066030724,0.80473,0.0010987988,0.000109277265,0.02218019,0.0052837874,0.0047770534,0.014449041,0.0013099378,0.0025575913,0.13284291],"study_design_scores_gemma":[0.007525408,0.000052454987,0.904565,0.0016779586,0.00041271406,0.000021427853,0.001213924,0.025380872,0.032990564,0.006845683,0.017880147,0.0014338832],"about_ca_topic_score_codex":0.0003581431,"about_ca_topic_score_gemma":0.0013238149,"teacher_disagreement_score":0.13140903,"about_ca_system_score_codex":0.00052086124,"about_ca_system_score_gemma":0.00065039034,"threshold_uncertainty_score":0.99983674},"labels":[],"label_agreement":null},{"id":"W3135992875","doi":"10.1111/jgh.15504","title":"Systemic quinolones and risk of acute liver failure III: A nested case–control study using a US electronic health records database","year":2021,"lang":"en","type":"article","venue":"Journal of Gastroenterology and Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario; Statistics Canada; Institut du Savoir Montfort; NOSM University; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; University of Ottawa","keywords":"Medicine; Nested case-control study; Odds ratio; Incidence (geometry); Confidence interval; Confounding; Internal medicine; Pediatrics","score_opus":0.05458400036168017,"score_gpt":0.373885281112617,"score_spread":0.31930128075093683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135992875","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932166,0.0030544265,0.0017346074,0.000589182,0.00072084804,0.0005043164,0.00016202789,0.000014927992,0.0000030677963],"genre_scores_gemma":[0.9931284,0.005514791,0.00032300045,0.0008420349,0.00014809909,0.00001235594,0.0000044375693,0.000017916247,0.000008945545],"study_design_codex":"observational","study_design_gemma":"case_report","domain_scores_codex":[0.99336874,0.0045189876,0.0010176105,0.00034998875,0.00011194502,0.00063269597],"domain_scores_gemma":[0.99760795,0.00031573584,0.00134016,0.00019264298,0.00029342412,0.00025006555],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0020144668,0.00027458268,0.0011482289,0.00032280825,0.00037846895,0.000013192416,0.00013678725,0.0003961193,0.00007503525],"category_scores_gemma":[0.00008042637,0.0002560144,0.00013464148,0.00016421491,0.00028315018,0.00020311822,0.00010984364,0.0018114835,0.0000011444133],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005518004,0.00062985276,0.97404695,0.00015123002,0.0031271912,0.0058360263,0.0015042188,0.00005503792,0.0069502927,0.000055450157,0.00006663736,0.0020590979],"study_design_scores_gemma":[0.03227454,0.020737238,0.13788137,0.0002227574,0.008369884,0.7796884,0.0043841666,0.012390757,0.0023132276,0.00029938912,0.0009440234,0.0004942462],"about_ca_topic_score_codex":0.00046991318,"about_ca_topic_score_gemma":0.0055803703,"teacher_disagreement_score":0.8361656,"about_ca_system_score_codex":0.000112647365,"about_ca_system_score_gemma":0.00035741535,"threshold_uncertainty_score":0.9999892},"labels":[],"label_agreement":null},{"id":"W3136412351","doi":"10.1002/iub.2467","title":"The effect of Chinese herbal medicine on digestive system and liver functions should not be neglected in COVID‐19: An updated systematic review and meta‐analysis","year":2021,"lang":"en","type":"review","venue":"IUBMB Life","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"China Postdoctoral Science Foundation","keywords":"Coronavirus disease 2019 (COVID-19); Meta-analysis; Traditional medicine; 2019-20 coronavirus outbreak; Medicine; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Traditional Chinese medicine; Alternative medicine; Intensive care medicine; Internal medicine; Virology; Pathology; Infectious disease (medical specialty); Disease","score_opus":0.2158943698688299,"score_gpt":0.4770776636374779,"score_spread":0.261183293768648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3136412351","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00026102617,0.9926612,0.000019273306,0.00085384346,0.0002849931,0.005358506,0.0003094163,0.00008068385,0.00017108921],"genre_scores_gemma":[0.012073138,0.9837205,0.0000030259769,0.0019250775,0.000100728736,0.0015649879,0.0003871991,0.000041226827,0.00018410828],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9845039,0.012675459,0.0014547014,0.00067971007,0.0003358401,0.0003503806],"domain_scores_gemma":[0.9923051,0.0054018665,0.0010112011,0.0005571471,0.00013826978,0.00058644154],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0040289867,0.0007172938,0.006797401,0.00044102976,0.00047005434,0.00004145339,0.00029255217,0.0008100297,0.00032407913],"category_scores_gemma":[0.002591704,0.00038849912,0.00069866655,0.002068715,0.00030445567,0.00011287764,0.000104240826,0.0016942631,0.000009481493],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017089806,0.00012125859,0.00004151895,0.89198905,0.102097385,0.00010066166,0.00037410404,0.000051354487,0.000007098547,0.0001713545,0.00035455372,0.0045207697],"study_design_scores_gemma":[0.0010603616,0.00070467405,0.000027462484,0.029267933,0.9054523,0.00020064111,0.00010905347,0.0005773653,0.000009849915,0.0000027171784,0.062003545,0.0005840942],"about_ca_topic_score_codex":0.00025858716,"about_ca_topic_score_gemma":0.0002820101,"teacher_disagreement_score":0.8627211,"about_ca_system_score_codex":0.00021173431,"about_ca_system_score_gemma":0.00026348603,"threshold_uncertainty_score":0.9998567},"labels":[],"label_agreement":null},{"id":"W3137866140","doi":"10.3390/ijms22063281","title":"Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice","year":2021,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Acetaminophen; Necrosis; Liver injury; Apoptosis; Liver transplantation; Medicine; Toxicity; Internal medicine; Unfolded protein response; Tumor necrosis factor alpha; Programmed cell death; Endocrinology; Pharmacology; Chemistry; Transplantation; Biochemistry","score_opus":0.13401107768501455,"score_gpt":0.4402418267532602,"score_spread":0.30623074906824566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3137866140","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99448335,0.00035492185,0.00018593346,0.0014599215,0.0013285328,0.000089085355,0.000017118933,0.0000045464294,0.0020765753],"genre_scores_gemma":[0.9985807,0.00011416142,0.00029984143,0.00079813687,0.00013464155,0.0000022377733,0.000001839102,0.0000061310066,0.00006230564],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99814034,0.00045203752,0.00044203686,0.00018291769,0.0005823889,0.00020027084],"domain_scores_gemma":[0.99884826,0.00023328324,0.00040367778,0.00007311522,0.0003403919,0.00010126013],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011866249,0.00013020863,0.00022016073,0.0003507571,0.000080937854,0.000058396738,0.0005679101,0.00015081571,0.00038058762],"category_scores_gemma":[0.00018510697,0.000110409484,0.00019171611,0.00034723108,0.00021402618,0.00027240816,0.00007846212,0.0005794054,0.000016012455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003761115,0.00064396876,0.014481614,0.000014453933,0.0002034179,0.0022707714,0.0011483761,0.0060113547,0.96473384,0.0015495215,0.00012552607,0.008441039],"study_design_scores_gemma":[0.0013147851,0.00036645797,0.020126171,0.00009785398,0.00003199825,0.00043123704,0.00017173469,0.0015789774,0.97356254,0.0010404006,0.0011426738,0.0001351499],"about_ca_topic_score_codex":0.00009273327,"about_ca_topic_score_gemma":0.000043591128,"teacher_disagreement_score":0.008828715,"about_ca_system_score_codex":0.00015500236,"about_ca_system_score_gemma":0.00049782946,"threshold_uncertainty_score":0.45023683},"labels":[],"label_agreement":null},{"id":"W3138079302","doi":"10.3390/ijms22062954","title":"Idiosyncratic Drug-Induced Liver Injury: Mechanistic and Clinical Challenges","year":2021,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Mitacs; University of Toronto","keywords":"Immune system; Liver injury; Biology; Innate immune system; Acquired immune system; Cytotoxic T cell; Immunology; CD8; Antigen; Inflammation; Oxidative stress; Autoimmunity; Pharmacology; Genetics; Biochemistry","score_opus":0.3537588585131145,"score_gpt":0.5423861288860732,"score_spread":0.18862727037295868,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3138079302","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.003238943,0.9883086,0.00021031611,0.00055992545,0.0065977247,0.00027871283,0.000019048299,0.000013961717,0.00077274715],"genre_scores_gemma":[0.016044818,0.9822599,0.00049890316,0.00037240222,0.00074544013,0.00001087245,0.0000036463377,0.000019367906,0.000044622167],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99545217,0.0020274564,0.0011519894,0.00041237072,0.0006982875,0.00025773817],"domain_scores_gemma":[0.9972076,0.00078001653,0.0012010748,0.00012530795,0.00045303386,0.0002329999],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0042472156,0.0003139687,0.0010685781,0.00044483753,0.00018183871,0.0001358507,0.0009830337,0.00051326386,0.00014004561],"category_scores_gemma":[0.0006519451,0.00025538466,0.000581096,0.00024017507,0.00029868478,0.00021716287,0.0002351318,0.0016481237,0.00003224568],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013675675,0.00013087878,0.000005601743,0.00039169364,0.0006910745,0.00073095784,0.00010332673,0.0000026040398,0.000114035574,0.0036532383,0.00008366461,0.99407923],"study_design_scores_gemma":[0.00051461894,0.00044223113,0.000009798354,0.0044372207,0.0012906989,0.0022426208,0.00015137365,0.00017580602,0.0010428703,0.0021438182,0.98706883,0.0004800916],"about_ca_topic_score_codex":0.000007812686,"about_ca_topic_score_gemma":0.000010253726,"teacher_disagreement_score":0.9935992,"about_ca_system_score_codex":0.000117606454,"about_ca_system_score_gemma":0.0008252974,"threshold_uncertainty_score":0.99998987},"labels":[],"label_agreement":null},{"id":"W3139314105","doi":"10.1093/pch/pxaa137","title":"Newly approved IV acetaminophen in Canada: Switching from oral to IV acetaminophen. Is IV worth the price difference? A systematic review","year":2021,"lang":"en","type":"review","venue":"Paediatrics & Child Health","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Western University; Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; Université de Sherbrooke","funders":"","keywords":"Medicine; Acetaminophen; Observational study; Oral administration; Route of administration; Bioavailability; Clinical trial; Intensive care unit; Anesthesia; Emergency medicine; Intensive care medicine; Internal medicine; Pharmacology","score_opus":0.11363354821276272,"score_gpt":0.39471057551751565,"score_spread":0.2810770273047529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3139314105","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004913502,0.9758972,0.00019326754,0.0058720745,0.002926312,0.013443778,0.0007347193,0.00009845602,0.00034282304],"genre_scores_gemma":[0.0010134723,0.96428615,0.00019609185,0.030632269,0.0011080544,0.0019954396,0.0003765802,0.00014399564,0.00024796207],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.9846145,0.007557311,0.0034834568,0.001587482,0.0009754468,0.0017817854],"domain_scores_gemma":[0.9919807,0.0028019205,0.0025302563,0.0014171854,0.00020067857,0.0010692744],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0051326198,0.0013842146,0.0064116996,0.00042667816,0.0010478864,0.0001235984,0.0017515443,0.0010490343,0.00026080981],"category_scores_gemma":[0.0012653805,0.0010411509,0.0007799665,0.0029621697,0.000049155504,0.00013622508,0.00058027107,0.0070349574,0.00018321641],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":true,"about_ca_system_consensus":true,"study_design_scores_codex":[0.00002593493,0.00030477816,0.00038269197,0.63540524,0.0007480503,0.00009077428,0.0022518693,0.00001873054,7.578401e-7,0.00012382277,0.0064462083,0.35420117],"study_design_scores_gemma":[0.0012752856,0.00015390394,0.00036841133,0.2069195,0.0051457416,0.00011384662,0.0003383184,0.00042796158,0.0000021401816,0.0001004701,0.78326875,0.0018856372],"about_ca_topic_score_codex":0.25648236,"about_ca_topic_score_gemma":0.3466956,"teacher_disagreement_score":0.77682257,"about_ca_system_score_codex":0.004163567,"about_ca_system_score_gemma":0.010763723,"threshold_uncertainty_score":0.99989086},"labels":[],"label_agreement":null},{"id":"W3147408645","doi":"10.14205/2309-4435.2013.01.02.2","title":"Alternanthera sessilis and Alternanthera bettzickiana Improved Superoxide Dismutase and Catalase Activities in the Livers of Ovariectomized Mice","year":2013,"lang":"en","type":"article","venue":"Journal of Applied Biopharmaceutics and Pharmacokinetics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Ovariectomized rat; Catalase; Superoxide dismutase; Biology; Food science; Botany; Horticulture; Enzyme; Biochemistry","score_opus":0.04555842837514172,"score_gpt":0.35419643524408645,"score_spread":0.3086380068689447,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3147408645","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947595,0.0024101033,0.00006805921,0.0009787844,0.000508961,0.0009201841,0.00010667122,0.00001283487,0.00023489691],"genre_scores_gemma":[0.98334783,0.014152949,0.00041932834,0.0017044051,0.000280186,0.0000375277,0.000005486176,0.000031974745,0.000020334941],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99777937,0.0003773332,0.00083779386,0.0002949535,0.00027091135,0.00043962811],"domain_scores_gemma":[0.9979971,0.00077850424,0.0006457836,0.00014473683,0.00012225019,0.00031161093],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014001159,0.00038447627,0.0005863921,0.0002737361,0.00021782803,0.00010435659,0.00031933605,0.00026280934,0.00011945296],"category_scores_gemma":[0.000031259646,0.00028711473,0.00009445511,0.00025593655,0.00056688004,0.00029465868,0.00012583686,0.0014062874,0.0000020806433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017309964,0.00040009315,0.0022329006,0.0003048886,0.0003365369,0.00004824281,0.006426875,0.00011377764,0.91251814,0.00016421231,0.00019474931,0.075528555],"study_design_scores_gemma":[0.014518193,0.00044990907,0.0030774635,0.00010003885,0.0008302888,0.00042959495,0.0029419744,0.024897523,0.93360347,0.0009822836,0.0175345,0.0006347385],"about_ca_topic_score_codex":0.00015742204,"about_ca_topic_score_gemma":0.00001375121,"teacher_disagreement_score":0.07489382,"about_ca_system_score_codex":0.000041463438,"about_ca_system_score_gemma":0.00007406692,"threshold_uncertainty_score":0.9999581},"labels":[],"label_agreement":null},{"id":"W3149295991","doi":"10.1016/j.toxrep.2021.03.031","title":"Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy","year":2021,"lang":"en","type":"article","venue":"Toxicology Reports","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Renal replacement therapy; Medicine; Metabolic acidosis; acetaminophen overdose; Acetaminophen; Lactic acidosis; Hemodialysis; Intensive care medicine; Refractory (planetary science); Acute kidney injury; Acetylcysteine; Fulminant hepatic failure; Acidosis; Anesthesia; Internal medicine; Liver transplantation; Transplantation","score_opus":0.07470429435108071,"score_gpt":0.3791759640334719,"score_spread":0.3044716696823912,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3149295991","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98540455,0.002476809,0.0002863943,0.002699338,0.0013800267,0.0013167766,0.00003141709,0.0002001083,0.0062045995],"genre_scores_gemma":[0.9839706,0.0012235389,0.0011290811,0.0072147306,0.00036937237,0.000598621,0.00004541143,0.00006419501,0.005384473],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9961287,0.00094037806,0.0007397412,0.0010869604,0.00032078728,0.00078343134],"domain_scores_gemma":[0.99772304,0.0002651571,0.00048490104,0.00068320025,0.00028876733,0.00055493356],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011802482,0.0004821461,0.00074855005,0.00023500505,0.00051730673,0.00005523056,0.00015447629,0.0007392083,0.0015684008],"category_scores_gemma":[0.00021882786,0.0004370606,0.000120808516,0.00058696594,0.0002469567,0.00025000723,0.00022214289,0.0011140809,0.00005044433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026609786,0.0010347579,0.024969291,0.00006533282,0.0011433491,0.00413799,0.001893061,0.00046347524,0.89986974,0.00060683215,0.0028923936,0.060262788],"study_design_scores_gemma":[0.0023538584,0.0010183541,0.013509997,0.00002646229,0.00018707183,0.002129522,0.00019584247,0.000047425237,0.50021774,0.00024706637,0.47956842,0.0004982668],"about_ca_topic_score_codex":0.000050557883,"about_ca_topic_score_gemma":0.00014869498,"teacher_disagreement_score":0.47667602,"about_ca_system_score_codex":0.00016838907,"about_ca_system_score_gemma":0.00039104375,"threshold_uncertainty_score":0.99980813},"labels":[],"label_agreement":null},{"id":"W3150039760","doi":"10.14740/ijcp143w","title":"A Child With Acute Liver and Kidney Failure Ongoing Encephalopathy: Effectiveness of Plasmapheresis on Acetaminophen Overdose, A Case Report","year":2014,"lang":"en","type":"article","venue":"International Journal of Clinical Pediatrics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Acetaminophen; Plasmapheresis; acetaminophen overdose; Encephalopathy; Liver failure; Hepatic encephalopathy; Analgesic; Acute kidney injury; Toxicity; Anesthesia; Intensive care medicine; Internal medicine; Cirrhosis; Acetylcysteine; Immunology","score_opus":0.06664782823721495,"score_gpt":0.43152161361495756,"score_spread":0.3648737853777426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3150039760","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931968,0.00006715546,0.0024148792,0.0005385179,0.0020410775,0.00021556315,0.000049941606,0.000014178804,0.0014618877],"genre_scores_gemma":[0.9963536,0.00047840673,0.00093839417,0.0005817895,0.0015792417,0.0000056562526,0.0000068814206,0.000017217966,0.00003880836],"study_design_codex":"observational","study_design_gemma":"case_report","domain_scores_codex":[0.99699175,0.001044423,0.0010491915,0.00025159397,0.0004887737,0.00017428437],"domain_scores_gemma":[0.9940464,0.0034826633,0.0013502516,0.00012597673,0.0006662695,0.0003284581],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004276073,0.00018443112,0.00048854563,0.00023307775,0.00011010618,0.000029476423,0.00026302514,0.00037594663,0.0000661978],"category_scores_gemma":[0.0031165837,0.00014762617,0.00019902387,0.00016815803,0.00016404565,0.00023728049,0.000077988916,0.0013994783,0.000006638443],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.029069435,0.0039784154,0.69260883,0.0006983128,0.0041550086,0.15058467,0.0012842581,0.003205425,0.0026235674,0.0038325812,0.00231673,0.105642766],"study_design_scores_gemma":[0.058229055,0.016957432,0.2509656,0.0020594143,0.0068428293,0.48481646,0.00047912388,0.010373884,0.0558223,0.0052272384,0.10569054,0.0025361413],"about_ca_topic_score_codex":0.000027979191,"about_ca_topic_score_gemma":0.000015428677,"teacher_disagreement_score":0.44164324,"about_ca_system_score_codex":0.000056326375,"about_ca_system_score_gemma":0.00023573598,"threshold_uncertainty_score":0.6080115},"labels":[],"label_agreement":null},{"id":"W3152835287","doi":"10.1016/j.jhep.2021.03.013","title":"A novel microRNA-based prognostic model outperforms standard prognostic models in patients with acetaminophen-induced acute liver failure","year":2021,"lang":"en","type":"article","venue":"Journal of Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; University of Alberta","funders":"Baylor University Medical Center; University of Alberta; University of California, San Diego; University of Oregon; University of Pittsburgh; University of California, Los Angeles; University of South Carolina; National Institute of Diabetes and Digestive and Kidney Diseases; Baylor University; Yale University; Virginia Commonwealth University; Northwestern University; Ohio State University; University of Washington; Roche Organ Transplant Research Foundation; Emory University; University of Pennsylvania; Massachusetts General Hospital","keywords":"Medicine; microRNA; Logistic regression; Acetaminophen; Internal medicine; Proportional hazards model; Liver failure; Time point; Oncology; Liver injury; Pharmacology; Biology; Gene","score_opus":0.07410665376391912,"score_gpt":0.33953259285801346,"score_spread":0.26542593909409434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3152835287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.985133,0.00015340556,0.011769449,0.0011330864,0.0007439254,0.0007780348,0.000089082845,0.00003444814,0.00016560151],"genre_scores_gemma":[0.9915546,0.000038746326,0.007041262,0.0010964625,0.0000979423,0.000052732965,0.00002833359,0.00005013651,0.00003978495],"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.996947,0.000515454,0.0009449158,0.00042116747,0.0004478735,0.0007236162],"domain_scores_gemma":[0.9973832,0.00035628848,0.0007034592,0.00024297589,0.0010096929,0.00030442546],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008114006,0.00041056913,0.00088505505,0.00040636162,0.00021929012,0.00003962324,0.00034343448,0.00076174975,0.00010973356],"category_scores_gemma":[0.00023397057,0.0003371242,0.00019996605,0.00049197517,0.00015377386,0.0004859899,0.00008510733,0.0022149645,0.000016084618],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0089341495,0.004425745,0.847773,0.0003267881,0.0012072228,0.0016045203,0.0019301759,0.06295969,0.062031504,0.00041955832,0.00031543165,0.008072181],"study_design_scores_gemma":[0.06549361,0.008224931,0.05149801,0.00079500204,0.003190205,0.0025926798,0.0005110381,0.6123371,0.24735945,0.003061895,0.0024257314,0.0025103053],"about_ca_topic_score_codex":0.000012297203,"about_ca_topic_score_gemma":0.00023711762,"teacher_disagreement_score":0.796275,"about_ca_system_score_codex":0.00035427083,"about_ca_system_score_gemma":0.0014040101,"threshold_uncertainty_score":0.9999081},"labels":[],"label_agreement":null},{"id":"W3153557095","doi":"10.21203/rs.3.rs-342681/v1","title":"Antimicrobial-associated Organ Injury among the Older Adults: A Systematic Review and Meta-Analysis","year":2021,"lang":"en","type":"review","venue":"Research Square","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Funnel plot; Medicine; Publication bias; Meta-analysis; Population; Cohort study; Systematic review; Cohort; Antimicrobial; MEDLINE; Internal medicine; Environmental health; Biology","score_opus":0.2983552733555416,"score_gpt":0.5389654199690131,"score_spread":0.24061014661347158,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3153557095","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00003464243,0.98687136,0.000004629674,0.0007522756,0.00012638107,0.011060582,0.0008278912,0.00008831512,0.00023394116],"genre_scores_gemma":[0.0007047005,0.9919196,0.000004648366,0.0009846784,0.00008274915,0.0035414896,0.00037303357,0.000083777275,0.0023053326],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.97144985,0.024388235,0.0014681689,0.0009761737,0.00076335965,0.0009542253],"domain_scores_gemma":[0.9928569,0.0039298027,0.0008311616,0.001072718,0.0009658218,0.00034355864],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.013005794,0.00071885635,0.0074789915,0.0007365274,0.0011868502,0.0002151335,0.0008700339,0.0013958148,0.002801888],"category_scores_gemma":[0.003260616,0.0004347627,0.003061985,0.0053581935,0.00043334102,0.00015071683,0.00052959396,0.0054302146,0.00023974477],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000054445704,0.00021399182,0.000008867938,0.84245205,0.14834425,0.000060735765,0.00027355537,4.98213e-7,6.9344077e-7,0.000039432925,0.0039299615,0.0046705552],"study_design_scores_gemma":[0.0001802396,0.00004932232,0.0000049240525,0.08359557,0.77548605,0.00003508393,0.00011243969,0.000018097302,0.000017458107,0.000007306891,0.13997994,0.0005135708],"about_ca_topic_score_codex":0.0001870062,"about_ca_topic_score_gemma":0.0002406035,"teacher_disagreement_score":0.7588565,"about_ca_system_score_codex":0.0003522284,"about_ca_system_score_gemma":0.00047054183,"threshold_uncertainty_score":0.9999006},"labels":[],"label_agreement":null},{"id":"W3153863274","doi":"10.1136/gutjnl-2020-basl.9","title":"O9 Redefining poor prognostic criteria for acetaminophen-induced acute liver failure using regeneration and cell-death linked miRNA signatures","year":2020,"lang":"en","type":"article","venue":"Abstracts","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; University of Alberta","funders":"","keywords":"microRNA; Medicine; Liver transplantation; Logistic regression; Receiver operating characteristic; Internal medicine; Liver failure; Retrospective cohort study; Oncology; Transplantation; Biology; Gene","score_opus":0.2065039124448524,"score_gpt":0.40276455748451084,"score_spread":0.19626064503965845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3153863274","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99434185,0.0002460606,0.0005074757,0.002187424,0.00070904987,0.0013275828,0.00007644184,0.00015010581,0.0004540084],"genre_scores_gemma":[0.99128467,0.00006816695,0.0048835054,0.002627141,0.00082064094,0.00009833485,0.000085928295,0.000044723172,0.00008686361],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998272,0.00023289806,0.00040158193,0.0005036697,0.00014301216,0.0004468429],"domain_scores_gemma":[0.998861,0.0003308957,0.00026189515,0.000114613205,0.0001333773,0.00029822756],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00044187048,0.00030367408,0.00030189104,0.000078682395,0.0005700691,0.000106795655,0.00013749806,0.00073388295,0.00009611086],"category_scores_gemma":[0.00023986775,0.0003136677,0.000091200476,0.00014699146,0.000049392933,0.00032754117,0.000059554226,0.0009469135,0.00003283938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003471998,0.00009490263,0.00022034938,0.00019002895,0.00012242592,0.00006908498,0.0016661785,0.00068082556,0.99185663,0.00015185076,0.00079583446,0.0038046944],"study_design_scores_gemma":[0.0023017193,0.00047356664,0.0035278366,0.000053220057,0.00054799847,0.000050447536,0.00016080441,0.06662897,0.9174802,0.000247709,0.00799894,0.000528626],"about_ca_topic_score_codex":0.000039880422,"about_ca_topic_score_gemma":0.000018176119,"teacher_disagreement_score":0.074376464,"about_ca_system_score_codex":0.000055105742,"about_ca_system_score_gemma":0.000099326724,"threshold_uncertainty_score":0.9999315},"labels":[],"label_agreement":null},{"id":"W3163365580","doi":"10.1503/cmaj.202026-f","title":"Atteinte hépatique médicamenteuse","year":2021,"lang":"fr","type":"article","venue":"Canadian Medical Association Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Incidence (geometry); Gynecology; Physics","score_opus":0.05554991431042366,"score_gpt":0.3760116485280639,"score_spread":0.32046173421764024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3163365580","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.1606963,0.013130623,0.0007575139,0.7224751,0.047092903,0.00041420848,0.00041293178,0.00006502278,0.054955363],"genre_scores_gemma":[0.52847594,0.021641765,0.00044530322,0.29342785,0.02480534,0.000057215024,0.00010156051,0.00011750471,0.13092753],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99265635,0.0036186047,0.0008786593,0.00035765,0.0011805935,0.001308172],"domain_scores_gemma":[0.99302423,0.0007146617,0.00045403422,0.00016982529,0.0010671028,0.004570127],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.005550439,0.0002994557,0.0004337238,0.000227521,0.0011230154,0.00021134288,0.00037209524,0.0030774157,0.09972257],"category_scores_gemma":[0.0048078815,0.00036061803,0.00031716583,0.00056767865,0.00016235738,0.00032363593,0.00005814485,0.008005433,0.0033803224],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":true,"study_design_scores_codex":[0.000032641517,0.00037886784,0.032440674,0.00008471687,0.0010676874,0.008335501,0.0012478635,0.00006718029,0.0007273178,0.0042876895,0.6079213,0.34340858],"study_design_scores_gemma":[0.0016436792,0.0000685918,0.002608522,0.00019992876,0.00017103917,0.0029887015,0.00046561827,0.0012967025,0.0031232445,0.0011006047,0.98598826,0.00034509954],"about_ca_topic_score_codex":0.0045922054,"about_ca_topic_score_gemma":0.08295077,"teacher_disagreement_score":0.4290473,"about_ca_system_score_codex":0.004054182,"about_ca_system_score_gemma":0.012923322,"threshold_uncertainty_score":0.9998846},"labels":[],"label_agreement":null},{"id":"W3168396934","doi":"10.52711/0974-360x.2021.00510","title":"Hypouricemic Significance of Ledum Palustre (Marsh Tea): A Review","year":2021,"lang":"en","type":"review","venue":"Research Journal of Pharmacy and Technology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Allopurinol; Uric acid; Traditional medicine; Evergreen; Shrub; Toxicology; Botany; Medicine; Biology; Chemistry; Internal medicine","score_opus":0.4214169925239461,"score_gpt":0.5830227002934255,"score_spread":0.1616057077694794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3168396934","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003512615,0.994798,0.000020315347,0.0017962381,0.00073421554,0.0014964674,0.00008815339,0.000038389866,0.00067697145],"genre_scores_gemma":[0.0012559708,0.99736106,0.00015656085,0.00013630268,0.0004488717,0.00015676457,0.000017391772,0.00005706612,0.00041001718],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9919279,0.0040492965,0.001960955,0.000528599,0.0006631421,0.0008700906],"domain_scores_gemma":[0.9943696,0.0017205008,0.0016190539,0.00042051214,0.0014963074,0.00037401967],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.007888765,0.0005124692,0.0030088068,0.0018602046,0.00034574498,0.000026356345,0.0011365052,0.001182374,0.0007883235],"category_scores_gemma":[0.0017846944,0.000431978,0.00060162315,0.002953705,0.0010801358,0.00019213607,0.00046082996,0.010003262,0.000037802703],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006199603,0.00034926468,0.000044736025,0.045329392,0.00076237076,0.00055534084,0.000031355234,3.3607768e-7,0.0016052277,0.00047768533,0.008269812,0.9425125],"study_design_scores_gemma":[0.0010095745,0.00027515518,2.4096136e-7,0.02631615,0.0012996993,0.0027106805,0.000059609192,0.00001454908,0.0055834753,0.00059326395,0.9618256,0.00031201172],"about_ca_topic_score_codex":0.000016721448,"about_ca_topic_score_gemma":0.0000027922017,"teacher_disagreement_score":0.95355576,"about_ca_system_score_codex":0.00025367158,"about_ca_system_score_gemma":0.0022386329,"threshold_uncertainty_score":0.9998132},"labels":[],"label_agreement":null},{"id":"W3171068542","doi":"10.15562/phytomedicine.2020.118","title":"Assessment of thrombolytic, antioxidant and analgesic properties of a medicinal plant of Asteraceae family growing in Bangladesh","year":2020,"lang":"en","type":"article","venue":"Discovery Phytomedicine - Journal of Natural Products Research and Ethnopharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Asteraceae; Traditional medicine; Antioxidant; Analgesic; Medicinal plants; Medicine; Biology; Botany; Pharmacology","score_opus":0.23051805882317952,"score_gpt":0.46184886331209174,"score_spread":0.23133080448891222,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3171068542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9762962,0.016451217,0.000011607476,0.005822639,0.0006728891,0.000602182,0.000033071836,0.0000050919616,0.000105128216],"genre_scores_gemma":[0.9939458,0.0050265584,0.00009596207,0.00044533648,0.00043880922,0.0000075872276,0.0000045297684,0.000014765623,0.000020688944],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99630994,0.0010971173,0.0011220607,0.0003259078,0.00068220374,0.00046278336],"domain_scores_gemma":[0.99780536,0.0005476278,0.00063662004,0.000104409766,0.00068076374,0.00022523873],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0036240264,0.00022302699,0.0009984951,0.00069573155,0.0000988169,0.000010415323,0.00028934333,0.00020215084,0.000024509485],"category_scores_gemma":[0.0005827644,0.00016193009,0.00006901942,0.0009127986,0.0013216885,0.0006322469,0.0001816054,0.0026310633,3.3374604e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0031612292,0.00042320933,0.00943919,0.0020544112,0.00033284337,0.00014412045,0.0022760278,0.00006446209,0.97759223,0.00010513414,0.0003221943,0.004084925],"study_design_scores_gemma":[0.0060343635,0.004279061,0.0687617,0.00076870626,0.00017790572,0.00014416776,0.0027213702,0.0019442057,0.91429704,0.00022908417,0.0004611362,0.00018127526],"about_ca_topic_score_codex":0.00006840641,"about_ca_topic_score_gemma":0.000005436619,"teacher_disagreement_score":0.06329522,"about_ca_system_score_codex":0.00006452328,"about_ca_system_score_gemma":0.0004948108,"threshold_uncertainty_score":0.9996699},"labels":[],"label_agreement":null},{"id":"W3174171423","doi":"10.1096/fasebj.2018.32.1_supplement.lb654","title":"Deficiency of <i>N</i> ‐Acetyltransferase Potentiates Isoniazid‐Endobiotics Interactions and Contributes to Isoniazid Hepatotoxicity","year":2018,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences","keywords":"Isoniazid; Chemistry; Pharmacology; Niacin; Nicotinamide adenine dinucleotide phosphate; Biochemistry; Enzyme; Medicine; Oxidase test; Tuberculosis","score_opus":0.07471361453116508,"score_gpt":0.38903976740117496,"score_spread":0.31432615287000987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174171423","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9833988,0.0004360906,0.008701535,0.0034084267,0.0019330201,0.00051249383,0.00011108719,0.000046104018,0.0014524541],"genre_scores_gemma":[0.9962921,0.00036220418,0.00027534636,0.0024147995,0.00041691784,0.000013552772,0.0000025825025,0.000019726178,0.00020277973],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979458,0.0006078445,0.0005386654,0.00023006588,0.00018988339,0.00048774213],"domain_scores_gemma":[0.9985241,0.00044098284,0.00021490644,0.00020278778,0.00033915637,0.0002780436],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015542873,0.00023272706,0.00031217615,0.00020559678,0.0012733567,0.00008091096,0.00034698698,0.00019796744,0.00040801396],"category_scores_gemma":[0.00022047608,0.00017659544,0.00013791026,0.00042734988,0.0005135348,0.0002064658,0.000092374576,0.0013013732,0.0001050391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054351933,0.00033011156,0.011485116,0.000031931657,0.00017948453,0.00001195095,0.0017203786,0.00013485366,0.97291493,0.0013802935,0.0013748794,0.009892548],"study_design_scores_gemma":[0.0012192636,0.00045241072,0.0026799338,0.00006103727,0.00021787679,0.00047247397,0.00045543563,0.0015106319,0.9786616,0.0018764762,0.012181143,0.00021173156],"about_ca_topic_score_codex":0.000077632925,"about_ca_topic_score_gemma":0.00015223665,"teacher_disagreement_score":0.012893302,"about_ca_system_score_codex":0.000085631895,"about_ca_system_score_gemma":0.000121832694,"threshold_uncertainty_score":0.97937596},"labels":[],"label_agreement":null},{"id":"W3175444389","doi":"10.22271/plants.2021.v9.i3a.1292","title":"Hepatoprotective plants role in human health: A cross-kingdom review","year":2021,"lang":"en","type":"review","venue":"Journal of Medicinal Plants Studies","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"FPInnovations","funders":"Science and Engineering Research Board; Department of Science and Technology, Ministry of Science and Technology, India","keywords":"Detoxification (alternative medicine); Human health; Biology; Medicine; Pharmacology; Environmental health; Alternative medicine; Pathology","score_opus":0.47433098609054214,"score_gpt":0.6021882068171928,"score_spread":0.12785722072665062,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175444389","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00091618794,0.9935255,0.00000442378,0.0005020751,0.002827517,0.0014434776,0.0001372485,0.0000220981,0.0006214817],"genre_scores_gemma":[0.00055524166,0.99609584,0.000025949657,0.0015961777,0.0013884264,0.00011773443,0.00003562222,0.000044945064,0.00014006144],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99230593,0.0029923897,0.0028220653,0.0004666311,0.00069010403,0.00072289247],"domain_scores_gemma":[0.9946758,0.0011862982,0.0032334963,0.00023529808,0.00032994297,0.00033912767],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.006924178,0.0006900977,0.005478436,0.00061839103,0.0005278262,0.000024241815,0.0005268851,0.00073569466,0.00017476604],"category_scores_gemma":[0.00095597596,0.00051390304,0.0006841754,0.0004441433,0.00027555804,0.00017847384,0.00018570421,0.0056135315,0.000032320004],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011394169,0.00035762918,0.00018735473,0.051556125,0.0021763395,0.002009684,0.0013368498,0.0000046005025,0.00001018989,0.00004733622,0.00683166,0.9353683],"study_design_scores_gemma":[0.0010442476,0.00046722236,0.00003608473,0.17158842,0.000659865,0.0032025534,0.00039111899,0.0000017156215,0.00003172325,0.00018409219,0.822051,0.00034194594],"about_ca_topic_score_codex":0.00010123726,"about_ca_topic_score_gemma":0.00019050634,"teacher_disagreement_score":0.93502635,"about_ca_system_score_codex":0.0009000807,"about_ca_system_score_gemma":0.0009948021,"threshold_uncertainty_score":0.99973124},"labels":[],"label_agreement":null},{"id":"W3178353515","doi":"10.1155/2021/6695967","title":"Massive Acetaminophen Overdose Treated Successfully with N-Acetylcysteine, Fomepizole, and Hemodialysis","year":2021,"lang":"en","type":"article","venue":"Case Reports in Critical Care","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Health Services; University of Calgary","funders":"","keywords":"Acetylcysteine; Acetaminophen; Hemodialysis; Medicine; acetaminophen overdose; Anesthesia; Internal medicine; Chemistry","score_opus":0.09653110185048987,"score_gpt":0.43114949603956304,"score_spread":0.3346183941890732,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3178353515","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905817,0.0017918643,0.00012297103,0.0006583614,0.00044904187,0.00040316393,0.00008170572,0.00009103951,0.0058201673],"genre_scores_gemma":[0.99838996,0.00007393256,0.00032098312,0.0005757878,0.00015415903,0.00013987103,0.00006423241,0.000032492473,0.00024860314],"study_design_codex":"case_report","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975626,0.0005514573,0.0005001272,0.00068518455,0.00020729021,0.000493341],"domain_scores_gemma":[0.9982549,0.00048594284,0.00010243858,0.00034710992,0.0004590791,0.00035051006],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037893472,0.00029027075,0.0004633777,0.00014172982,0.00031782946,0.00006917703,0.000045498815,0.00051649194,0.00040694364],"category_scores_gemma":[0.0006783245,0.00027567716,0.00008996854,0.0005291382,0.0003253588,0.00022771634,0.00010377869,0.0009123694,0.0000075234148],"study_design_candidate":"case_report","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003905794,0.00039431924,0.08858051,0.0010150134,0.0001823901,0.86053723,0.0023195734,0.00042700375,0.014634944,0.0009831128,0.000096013355,0.030439287],"study_design_scores_gemma":[0.0073832544,0.00091911026,0.0098146135,0.00041080947,0.0020310848,0.33478153,0.022640282,0.002361583,0.59034556,0.001985081,0.024987422,0.0023396718],"about_ca_topic_score_codex":0.00020981023,"about_ca_topic_score_gemma":0.00067628955,"teacher_disagreement_score":0.5757106,"about_ca_system_score_codex":0.00020610802,"about_ca_system_score_gemma":0.00020774682,"threshold_uncertainty_score":0.99996954},"labels":[],"label_agreement":null},{"id":"W3185172885","doi":"10.2196/29226","title":"Predicting Antituberculosis Drug–Induced Liver Injury Using an Interpretable Machine Learning Method: Model Development and Validation Study","year":2021,"lang":"en","type":"article","venue":"JMIR Medical Informatics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Sanming Project of Medicine in Shenzhen; Science, Technology and Innovation Commission of Shenzhen Municipality","keywords":"Medicine; Receiver operating characteristic; Pyrazinamide; Ethambutol; Liver injury; Aspartate transaminase; Tuberculosis; Internal medicine; Machine learning; Artificial intelligence; Mycobacterium tuberculosis; Pathology","score_opus":0.1489582230874151,"score_gpt":0.45395172504896714,"score_spread":0.30499350196155206,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3185172885","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98160344,0.000041800144,0.01638133,0.00005345789,0.00037612134,0.0006353424,0.000009383334,0.00015461212,0.0007444822],"genre_scores_gemma":[0.9839696,0.000057687652,0.014825369,0.0007654138,0.00010636101,0.000079084966,0.000062334686,0.000023588656,0.00011053395],"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9971346,0.0008905348,0.0008231213,0.0002362074,0.0005226304,0.0003929001],"domain_scores_gemma":[0.9987776,0.00021348955,0.00026107527,0.00016908391,0.00016079276,0.0004179042],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0027893868,0.00025378837,0.0003499632,0.00016560688,0.00068107975,0.00008806422,0.00018023624,0.00044222057,0.0002907816],"category_scores_gemma":[0.00028622543,0.00024911328,0.00004915433,0.00031050554,0.000055438653,0.0008068323,0.0002969874,0.001790574,0.000019165223],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041710082,0.0037910654,0.100755855,0.0012653343,0.0009221892,0.00013260315,0.27411422,0.023802005,0.02872907,0.00028507688,0.00009450205,0.565691],"study_design_scores_gemma":[0.00085852994,0.00010731501,0.00030714387,0.00007850183,0.00010403872,0.00006656156,0.0047504716,0.92927116,0.06288091,0.000036431717,0.0012704929,0.0002684646],"about_ca_topic_score_codex":0.00009530029,"about_ca_topic_score_gemma":0.00009969353,"teacher_disagreement_score":0.9054691,"about_ca_system_score_codex":0.00013732324,"about_ca_system_score_gemma":0.00034609597,"threshold_uncertainty_score":0.9999961},"labels":[],"label_agreement":null},{"id":"W3186887221","doi":"10.1139/cjpp-2020-0763","title":"S-ketamine alleviates carbon tetrachloride-induced hepatic injury and oxidative stress by targeting the Nrf2/HO-1 signaling pathway","year":2021,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Oxidative stress; Superoxide dismutase; Aspartate transaminase; Liver injury; Glutathione; Alanine transaminase; Glutathione peroxidase; Malondialdehyde; Chemistry; Alkaline phosphatase; Liver cell; Pharmacology; Biochemistry; Biology; Internal medicine; Endocrinology; Medicine; Enzyme","score_opus":0.044151250907993406,"score_gpt":0.3353825619205496,"score_spread":0.29123131101255617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3186887221","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9892678,0.005097305,0.000011277726,0.002375946,0.0026126122,0.00028528325,0.00009348184,0.0000143004245,0.00024194497],"genre_scores_gemma":[0.9950532,0.0008117236,0.000033920245,0.0031041743,0.00080636336,0.000025286556,0.000026116682,0.000026901305,0.00011233222],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99640155,0.001846173,0.0006255554,0.0003650408,0.00010163763,0.0006600695],"domain_scores_gemma":[0.997317,0.0011090244,0.00047385725,0.00011048541,0.00033921882,0.0006504168],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012094694,0.00032706122,0.00056458067,0.00018372606,0.0007892249,0.0000320774,0.0002609272,0.0005321545,0.0007735652],"category_scores_gemma":[0.00024184065,0.00027181616,0.00010521605,0.00026364138,0.0005128977,0.00017451809,0.00006341172,0.0021059765,0.000004090511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018154895,0.00008005122,0.005062344,0.00010389105,0.00046237875,0.00018916916,0.0015675303,0.00008732482,0.98716825,0.00011002974,0.0009370682,0.00405043],"study_design_scores_gemma":[0.0012153095,0.0003800569,0.001008459,0.00003028159,0.00026441217,0.00021626883,0.0006512529,0.0004954473,0.97966474,0.0010477946,0.014741627,0.00028434393],"about_ca_topic_score_codex":0.0006900887,"about_ca_topic_score_gemma":0.00077616796,"teacher_disagreement_score":0.013804558,"about_ca_system_score_codex":0.00010558924,"about_ca_system_score_gemma":0.0007658829,"threshold_uncertainty_score":0.9999734},"labels":[],"label_agreement":null},{"id":"W3190418806","doi":"10.51441/biomedica/5-282","title":"Effects of Ribavirin on Thickness of Testicular Capsule in Albino Rats","year":2021,"lang":"en","type":"article","venue":"BIOMEDICA","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Continental (Canada)","funders":"","keywords":"Capsule; Medicine; Edema; Ribavirin; Andrology; Internal medicine; Endocrinology; Biology; Immunology","score_opus":0.06811014129445583,"score_gpt":0.39964542420943067,"score_spread":0.3315352829149748,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3190418806","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994434,0.0005820093,0.000073678224,0.00051122194,0.0012087558,0.00035743398,0.000024163437,0.000026132157,0.0027825977],"genre_scores_gemma":[0.9987774,0.00017424028,0.00012080179,0.0004966072,0.00009814624,0.00004436334,0.00001621362,0.0000113163005,0.00026091724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998385,0.0005912737,0.0003444791,0.00022861554,0.00021044668,0.00024018495],"domain_scores_gemma":[0.99898446,0.00051054085,0.00013996135,0.0001648324,0.00008521328,0.00011501949],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006335747,0.00013225464,0.00030560134,0.00016906676,0.00004742801,0.0000028498448,0.00014165102,0.00041213675,0.00032883685],"category_scores_gemma":[0.0005137172,0.00012777149,0.00007411479,0.0005399358,0.00021275647,0.000037512527,0.000055226163,0.00055036123,0.000060409166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009078674,0.0009548447,0.0010986843,0.0005643158,0.00006317916,0.00020893483,0.00051456946,0.000024888033,0.97952193,0.0005357714,0.00058109016,0.015840983],"study_design_scores_gemma":[0.0014839233,0.00016956808,0.008806061,0.0001636146,0.000051128125,0.000017944434,0.000033552333,0.00029580595,0.9723131,0.00034597138,0.016201442,0.00011789996],"about_ca_topic_score_codex":0.00006938534,"about_ca_topic_score_gemma":0.000014789547,"teacher_disagreement_score":0.015723083,"about_ca_system_score_codex":0.000046786277,"about_ca_system_score_gemma":0.00017998158,"threshold_uncertainty_score":0.52103704},"labels":[],"label_agreement":null},{"id":"W3195474249","doi":"10.3389/fchem.2021.736788","title":"Protein Targets of Acetaminophen Covalent Binding in Rat and Mouse Liver Studied by LC-MS/MS","year":2021,"lang":"en","type":"article","venue":"Frontiers in Chemistry","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Acetaminophen; Selected reaction monitoring; Tandem mass spectrometry; Chromatography; Biochemistry; Mass spectrometry","score_opus":0.0505498986069707,"score_gpt":0.3355226823311008,"score_spread":0.2849727837241301,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3195474249","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933348,0.0038866673,0.00012534196,0.00019579049,0.00046602657,0.00044176797,0.000071681294,0.000025828827,0.0014521426],"genre_scores_gemma":[0.99405825,0.0009908859,0.00083439786,0.00010820351,0.000069645306,0.00012717763,0.000050182898,0.000020021182,0.00374122],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99854624,0.00022882682,0.00036194458,0.00037937227,0.00013507128,0.00034852375],"domain_scores_gemma":[0.99949306,0.00005860581,0.00013824957,0.0001562712,0.000048490892,0.0001053092],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005325256,0.00020285204,0.00037192577,0.00006194528,0.00009257741,0.00001144938,0.00013924867,0.00047003277,0.00022392906],"category_scores_gemma":[0.00012414342,0.00023094802,0.000052364718,0.00025221027,0.00015901044,0.00009262826,0.000115924646,0.00091367034,0.000004255251],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017019187,0.00037510428,0.041471656,0.00053536304,0.00008262143,0.00008936641,0.0008425802,0.000051494007,0.9473906,0.0000042430106,0.0045798193,0.0044069663],"study_design_scores_gemma":[0.0018748001,0.000021113821,0.00032424976,0.000066649154,0.000027568705,0.000007665486,0.00050860737,0.00081983855,0.98026997,0.000091850496,0.015766026,0.00022163795],"about_ca_topic_score_codex":0.00003559486,"about_ca_topic_score_gemma":0.000021941716,"teacher_disagreement_score":0.041147407,"about_ca_system_score_codex":0.00020428623,"about_ca_system_score_gemma":0.00008496134,"threshold_uncertainty_score":0.9417787},"labels":[],"label_agreement":null},{"id":"W3195845431","doi":"10.1111/bcp.15049","title":"Pharmacokinetics of 2 oral paracetamol formulations in hospitalized octogenarians","year":2021,"lang":"en","type":"article","venue":"British Journal of Clinical Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Pharmacokinetics; Medicine; Dosing; Interquartile range; Analgesic; Bioequivalence; Acetaminophen; Trough Concentration; Pharmacology; Internal medicine","score_opus":0.22447889606580243,"score_gpt":0.5246169595739876,"score_spread":0.30013806350818517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3195845431","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98448473,0.0016410908,0.0005493599,0.0017462262,0.008542634,0.00043302396,0.000082592254,0.000024464242,0.0024959063],"genre_scores_gemma":[0.987868,0.0060275528,0.0015133275,0.0031490044,0.0010115055,0.000018583209,0.00001574586,0.00003227082,0.00036398473],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9927948,0.0029925136,0.003034815,0.00033614892,0.00031329136,0.00052839745],"domain_scores_gemma":[0.99580336,0.001419857,0.0013898251,0.00013250989,0.00084364426,0.00041080272],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0043206215,0.00023280241,0.0011983196,0.00022497242,0.00014824851,0.000024582892,0.00041750417,0.00073204905,0.0031421008],"category_scores_gemma":[0.0012493572,0.00028250646,0.0005937261,0.00062474346,0.00037773873,0.0003167603,0.00012286122,0.0029859578,0.000027272043],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040324354,0.0103053395,0.1586571,0.0002987547,0.0022030848,0.010217244,0.00063652237,0.010234187,0.13480331,0.00045326378,0.028835388,0.63932335],"study_design_scores_gemma":[0.04950228,0.0016092173,0.20754436,0.00029572676,0.0018260531,0.007105397,0.00020763333,0.008766424,0.19544546,0.0059124753,0.52076006,0.0010249069],"about_ca_topic_score_codex":0.00004157393,"about_ca_topic_score_gemma":0.00010036557,"teacher_disagreement_score":0.63829845,"about_ca_system_score_codex":0.00007723797,"about_ca_system_score_gemma":0.0006582569,"threshold_uncertainty_score":0.9999627},"labels":[],"label_agreement":null},{"id":"W3197484264","doi":"10.1016/j.jceh.2021.08.026","title":"Tinospora Cordifolia (Giloy) and Autoimmune-like Liver Injury – A Classic Case of Primum Non Nocere, “First, Do No Harm”","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical and Experimental Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Primum non nocere; Tinospora cordifolia; Medicine; Harm; Intensive care medicine; Traditional medicine; Law","score_opus":0.1338090212992655,"score_gpt":0.47464918172917525,"score_spread":0.3408401604299097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197484264","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909082,0.0035222732,0.000029649775,0.00046614793,0.0036154578,0.00021560518,0.000031509986,0.00001477028,0.0011963825],"genre_scores_gemma":[0.9946891,0.0026131566,0.00047464872,0.0015233734,0.00041504498,0.0000086353075,0.0000040113982,0.000020664558,0.00025137916],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99680007,0.00077767373,0.0015822207,0.00034833234,0.000150644,0.0003410828],"domain_scores_gemma":[0.9974198,0.0006505508,0.0010908056,0.00017185013,0.0002906622,0.00037637822],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012460668,0.00026291903,0.0010337486,0.00012046655,0.0002776844,0.000022705635,0.00014557257,0.000769516,0.00072748313],"category_scores_gemma":[0.00022583888,0.00023388978,0.00028615305,0.00015504475,0.0007569328,0.00021364649,0.00022415318,0.0015103652,0.000026160387],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.022334306,0.010054972,0.60565877,0.00096297037,0.002337876,0.029742671,0.005206004,0.000017471184,0.17388979,0.0023403375,0.016179148,0.13127568],"study_design_scores_gemma":[0.023560813,0.009831598,0.03505214,0.0003368947,0.0010434074,0.057043824,0.0025270903,0.008818829,0.5356093,0.0015389543,0.32325304,0.0013841338],"about_ca_topic_score_codex":0.00009278964,"about_ca_topic_score_gemma":0.000024381996,"teacher_disagreement_score":0.57060665,"about_ca_system_score_codex":0.000040103594,"about_ca_system_score_gemma":0.00023974071,"threshold_uncertainty_score":0.9537748},"labels":[],"label_agreement":null},{"id":"W3201145314","doi":"10.18311/ti/2021/v28i1/26394","title":"Reversal of Hepato-renal Impairment Induced by Meloxicam Paracetamol Toxicity in a Labrador Dog","year":2021,"lang":"en","type":"article","venue":"Toxicology International","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Lethargy; Abdomen; Hepatosplenomegaly; Anorexia; Pallor; Jaundice; Gastroenterology; Pathology; Internal medicine; Surgery","score_opus":0.07414078707582201,"score_gpt":0.40794524379976915,"score_spread":0.33380445672394715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3201145314","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9860779,0.0001472015,0.00019652865,0.0040130545,0.0024114202,0.00050234824,0.00026774578,0.00007659675,0.006307187],"genre_scores_gemma":[0.9949897,0.00011269874,0.00033407973,0.002736115,0.00025284005,0.00016751025,0.00015173916,0.000025573803,0.0012297292],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967324,0.0009377708,0.00083191565,0.00057763443,0.00036442085,0.00055586494],"domain_scores_gemma":[0.99853486,0.00040688613,0.00034549192,0.00025805406,0.00024195299,0.00021275142],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010538016,0.00031053598,0.00050789875,0.0002799088,0.00013906803,0.000021626443,0.00046631583,0.00084503065,0.005185973],"category_scores_gemma":[0.00032798492,0.0003440361,0.00019074175,0.00043857243,0.00020533646,0.00023511126,0.00022033461,0.0013813752,0.00014866768],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000708182,0.0027520116,0.018967612,0.000043446078,0.00042646157,0.0002957059,0.0008524525,0.00023057747,0.95739895,0.0024768005,0.0048962743,0.010951537],"study_design_scores_gemma":[0.004126491,0.00040153807,0.018157857,0.00003959979,0.00006404674,0.00020716606,0.00018451283,0.002189828,0.9427284,0.0009661248,0.03053681,0.00039764334],"about_ca_topic_score_codex":0.00017058999,"about_ca_topic_score_gemma":0.00050036557,"teacher_disagreement_score":0.025640536,"about_ca_system_score_codex":0.00041923622,"about_ca_system_score_gemma":0.00033889094,"threshold_uncertainty_score":0.9999012},"labels":[],"label_agreement":null},{"id":"W3202368121","doi":"10.1136/archdischild-2021-321952","title":"Dosing of enteral acetaminophen in critically ill children: a cohort study","year":2021,"lang":"en","type":"article","venue":"Archives of Disease in Childhood","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; University of Toronto; Institute for Clinical Evaluative Sciences; Women's College Hospital; Centre Hospitalier Universitaire Sainte-Justine; Hospital for Sick Children","funders":"","keywords":"Medicine; Acetaminophen; Dosing; Retrospective cohort study; Emergency medicine; Cohort study; Relative risk; Pediatrics; Cumulative dose; Enteral administration; Cohort; Anesthesia; Internal medicine; Confidence interval; Parenteral nutrition","score_opus":0.036210155223003575,"score_gpt":0.36845291137637654,"score_spread":0.33224275615337295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3202368121","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99568135,0.00026586902,0.000025781395,0.00033351028,0.0001997676,0.001282952,0.00012152241,0.000021178199,0.0020680577],"genre_scores_gemma":[0.99895996,0.000084001585,0.00021197768,0.00049761037,0.00006621104,0.00009693616,0.00004199016,0.000017815613,0.000023473836],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9974916,0.0009831537,0.00059627055,0.00039496442,0.00019364229,0.00034037067],"domain_scores_gemma":[0.99892837,0.0004126778,0.00011531087,0.00027920233,0.000069726244,0.00019471427],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037017168,0.00019125249,0.00040741605,0.00025327076,0.00006666169,0.000008635882,0.00022986783,0.000094241936,0.00016266716],"category_scores_gemma":[0.00049386354,0.00021018067,0.00014657754,0.00029956043,0.00018078666,0.00011157617,0.00016603059,0.0006698528,0.000005226926],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046692806,0.0066581955,0.9748179,0.00008787745,0.00015875969,0.00007837233,0.004005865,0.0004378406,0.006049183,0.0002606188,0.0000035122878,0.006974947],"study_design_scores_gemma":[0.00316838,0.00015155635,0.9790034,0.00014957704,0.00011048095,0.000005081386,0.00032498688,0.00042413903,0.013858602,0.002603644,0.000019968622,0.00018013145],"about_ca_topic_score_codex":0.00011018108,"about_ca_topic_score_gemma":0.00014772973,"teacher_disagreement_score":0.007809419,"about_ca_system_score_codex":0.000025073585,"about_ca_system_score_gemma":0.0001897538,"threshold_uncertainty_score":0.85709196},"labels":[],"label_agreement":null},{"id":"W3203501611","doi":"10.4212/cjhp.v74i4.3082","title":"Stability of N-Acetylcysteine 60 mg/mL in Extemporaneously Compounded Injectable Solutions","year":2021,"lang":"en","type":"article","venue":"The Canadian Journal of Hospital Pharmacy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"Institut National de Santé Publique du Québec; Université de Montréal; Université du Québec à Montréal","funders":"Institut National de Santé Publique du Québec","keywords":"Acetylcysteine; Medicine; Chemistry; Biochemistry","score_opus":0.14534276431868676,"score_gpt":0.3800734670242346,"score_spread":0.23473070270554786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203501611","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98448914,0.0022306757,0.000047668207,0.0067460933,0.002411141,0.00040630889,0.000093009716,0.000011615364,0.0035643259],"genre_scores_gemma":[0.9987299,0.00015358033,0.000078694626,0.0005935851,0.00026686466,0.000010704458,0.00000887848,0.000020677353,0.00013710734],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971616,0.0010198798,0.0008184002,0.00019202117,0.00022917995,0.00057886646],"domain_scores_gemma":[0.99794614,0.0003101443,0.00044452652,0.00024032111,0.00054168375,0.00051719183],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0022488767,0.00020556788,0.00043000706,0.00021513847,0.0005095592,0.000045016095,0.00043804513,0.00016313513,0.0013363238],"category_scores_gemma":[0.0003339081,0.00018275855,0.00020600195,0.00062464445,0.000400434,0.00029737194,0.0000485494,0.0016683834,0.000024310113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022873348,0.004123882,0.20210947,0.0008715633,0.002100096,0.008063302,0.04021056,0.012085836,0.67227876,0.00689838,0.017507745,0.031463068],"study_design_scores_gemma":[0.015310606,0.001408415,0.013335119,0.00030292367,0.00060774834,0.002144263,0.0041400883,0.0047848755,0.726124,0.011474398,0.21914051,0.0012270656],"about_ca_topic_score_codex":0.014782901,"about_ca_topic_score_gemma":0.077783614,"teacher_disagreement_score":0.20163277,"about_ca_system_score_codex":0.00048042124,"about_ca_system_score_gemma":0.0030132215,"threshold_uncertainty_score":0.99957657},"labels":[],"label_agreement":null},{"id":"W3204543229","doi":"10.2174/1875692118666210928170636","title":"Association of N-acetyltransferase-2 Polymorphism with AntituberculosisInduced Hepatotoxicity: A Meta-analysis","year":2021,"lang":"en","type":"article","venue":"Current pharmacogenomics and personalized medicine (Online)/Current pharmacogenomics and personalized medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Ministry of Higher Education, Malaysia","keywords":"Meta-analysis; Internal medicine; Genotype; Allele; Confidence interval; Medicine; Sample size determination; Polymorphism (computer science); Statistic; Genetics; Biology; Statistics; Gene","score_opus":0.25183903271997715,"score_gpt":0.445379740521194,"score_spread":0.19354070780121685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204543229","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.772642,0.20736901,0.0009479835,0.010837403,0.002566765,0.001618192,0.0035893293,0.00013273074,0.00029657158],"genre_scores_gemma":[0.73644024,0.25236785,0.0003657479,0.0044188877,0.0025967564,0.00022518577,0.0026322857,0.00017741782,0.0007756484],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9916607,0.0016231266,0.0021895987,0.001905604,0.0012635587,0.0013574039],"domain_scores_gemma":[0.99418616,0.0012096628,0.0014508005,0.00052742875,0.0010800508,0.0015458876],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0031751879,0.0014873334,0.0041826596,0.0010934264,0.00080996676,0.00006467986,0.00051949854,0.00057936076,0.0049410905],"category_scores_gemma":[0.00025726925,0.0012089148,0.0011962677,0.0019914834,0.0015289345,0.00035456245,0.00022137687,0.0027830028,0.0000087490625],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0047072545,0.0037068124,0.01781957,0.0029679874,0.15122712,0.00019965073,0.012258361,0.00020006909,0.7271007,0.0021442613,0.0035786955,0.07408958],"study_design_scores_gemma":[0.03901071,0.0008686322,0.0011359508,0.00044478397,0.36551318,0.00045511877,0.0019445756,0.012167689,0.033281874,0.00042443105,0.54227257,0.0024804918],"about_ca_topic_score_codex":0.00029579177,"about_ca_topic_score_gemma":0.00014768733,"teacher_disagreement_score":0.69381875,"about_ca_system_score_codex":0.0003905802,"about_ca_system_score_gemma":0.00058638584,"threshold_uncertainty_score":0.99978757},"labels":[],"label_agreement":null},{"id":"W3211872568","doi":"10.1080/15563650.2021.1998518","title":"Comparing development of liver injury using the two versus three bag acetylcysteine regimen despite early treatment in paracetamol overdose","year":2021,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Calgary; Alberta Health Services","funders":"National Health and Medical Research Council","keywords":"Regimen; Acetylcysteine; Medicine; Acetaminophen; Ingestion; acetaminophen overdose; Cohort; Surgery; Anesthesia; Internal medicine; Chemistry","score_opus":0.4896270767622958,"score_gpt":0.5285632420242261,"score_spread":0.03893616526193033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3211872568","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944299,0.00042710511,0.0004054113,0.0003620311,0.0026195997,0.0008641714,0.0000113881215,0.00004725107,0.0008331593],"genre_scores_gemma":[0.99616694,0.00020312691,0.0023809327,0.00055506907,0.00034926055,0.000114582224,0.0000116684405,0.000027596767,0.00019078968],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99524134,0.0020980898,0.001294155,0.00058928906,0.00017421324,0.0006029372],"domain_scores_gemma":[0.99664474,0.0021318218,0.00044280977,0.0004438699,0.00013201339,0.00020475732],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0021517852,0.00031648081,0.0008203733,0.00011757829,0.00033482333,0.000019776426,0.00033074763,0.000713699,0.00033026614],"category_scores_gemma":[0.0004163512,0.00026632595,0.00023620385,0.00044412207,0.00044349095,0.00012054762,0.0003063172,0.0012522084,0.00008243753],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015881196,0.007564066,0.49236557,0.00017901805,0.0023290792,0.00069412217,0.0056406427,0.005856733,0.17861584,0.004313244,0.00016855232,0.28639194],"study_design_scores_gemma":[0.039745674,0.0046126302,0.28044173,0.0001935981,0.00096485263,0.00012794729,0.0004864066,0.038484458,0.5080987,0.0011706686,0.12425062,0.0014226508],"about_ca_topic_score_codex":0.0001490117,"about_ca_topic_score_gemma":0.0032338959,"teacher_disagreement_score":0.3294829,"about_ca_system_score_codex":0.000547907,"about_ca_system_score_gemma":0.0006644924,"threshold_uncertainty_score":0.9999789},"labels":[],"label_agreement":null},{"id":"W3217102241","doi":"10.1016/j.sapharm.2021.11.008","title":"Deprescribing paracetamol in pain conditions: A scoping review","year":2021,"lang":"en","type":"review","venue":"Research in Social and Administrative Pharmacy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Deprescribing; Discontinuation; Medicine; Psychological intervention; Acetaminophen; Osteoarthritis; Tramadol; Physical therapy; Analgesic; Intensive care medicine; Alternative medicine; Polypharmacy; Anesthesia; Psychiatry","score_opus":0.8445864549296149,"score_gpt":0.698103644718567,"score_spread":0.14648281021104792,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3217102241","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00010896593,0.9899169,0.000007640958,0.000986088,0.00025127392,0.0050216313,0.00022546721,0.000037970953,0.003444055],"genre_scores_gemma":[0.0016606706,0.99354154,0.000022528038,0.00064480177,0.0005709626,0.0031872403,0.0002078713,0.000037907612,0.00012650157],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.97786206,0.018607644,0.0011994942,0.0008714764,0.00044449815,0.0010148517],"domain_scores_gemma":[0.99537826,0.0036375995,0.00031083255,0.00016607917,0.00018623627,0.0003209969],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.011309888,0.0005082597,0.002003341,0.00040058765,0.00077949464,0.000103966864,0.00035335965,0.0005797523,0.000690143],"category_scores_gemma":[0.0012251902,0.0005149811,0.00032603598,0.0021395492,0.0005429265,0.00026397838,0.0002510676,0.005063905,0.000059442118],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029614477,0.00038840083,0.00019621874,0.09388853,0.00011938287,0.0006705844,0.0003171952,2.9417686e-7,0.000010666074,0.000978902,0.00073986675,0.90266037],"study_design_scores_gemma":[0.0010376261,0.000069375994,0.00000945375,0.24915922,0.00018474458,0.00007483504,0.00027337085,0.0000351602,0.0000526771,0.00082215376,0.74770373,0.0005776457],"about_ca_topic_score_codex":0.0001488037,"about_ca_topic_score_gemma":0.00036524137,"teacher_disagreement_score":0.9020827,"about_ca_system_score_codex":0.00058685645,"about_ca_system_score_gemma":0.0027579812,"threshold_uncertainty_score":0.99973017},"labels":[],"label_agreement":null},{"id":"W37179616","doi":"10.1177/039139880803100511","title":"Acetaminophen-Induced Acute Liver Failure Treated with Single-Pass Albumin Dialysis: Report of a Case","year":2008,"lang":"en","type":"article","venue":"The International Journal of Artificial Organs","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Liver transplantation; Albumin; acetaminophen overdose; Acetaminophen; Hepatic encephalopathy; Dialysis; Liver function; Liver disease; Liver function tests; Coagulopathy; Bilirubin; Renal function; Acute kidney injury; Encephalopathy; Internal medicine; Gastroenterology; Hemofiltration; Hemodialysis; Anesthesia; Transplantation; Acetylcysteine; Cirrhosis","score_opus":0.12833877645148598,"score_gpt":0.3689211357702371,"score_spread":0.24058235931875113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W37179616","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951967,0.000034353314,0.000582064,0.002683841,0.00085886114,0.00022055363,0.00003108913,0.000022542283,0.00036998303],"genre_scores_gemma":[0.99826336,0.000042587388,0.0003063817,0.00031085245,0.0007671921,0.0000066862435,0.000007549512,0.000022113198,0.0002732981],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99797684,0.00033656764,0.00079183374,0.00017020357,0.0005101694,0.00021441358],"domain_scores_gemma":[0.99757975,0.00026442445,0.000987433,0.00017455479,0.000868309,0.00012555049],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082282786,0.00019343957,0.0003398722,0.00023095564,0.00027156202,0.000026959455,0.0004369844,0.00020853861,0.00035469557],"category_scores_gemma":[0.00015338504,0.00013267399,0.00018972137,0.00030751168,0.00022940309,0.00025679526,0.000056631503,0.0007989577,0.000027100794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020019275,0.0008145329,0.0025328838,0.000008160988,0.0026216537,0.045011304,0.004631076,0.000411604,0.9331944,0.00017536522,0.0006719367,0.0079251705],"study_design_scores_gemma":[0.00095863384,0.00046987072,0.00071878405,0.000031998166,0.00069311116,0.08959136,0.0005432348,0.00048841577,0.90241086,0.00012045898,0.0037983875,0.00017487719],"about_ca_topic_score_codex":0.00020159966,"about_ca_topic_score_gemma":0.00039855475,"teacher_disagreement_score":0.044580057,"about_ca_system_score_codex":0.00015852791,"about_ca_system_score_gemma":0.00022704563,"threshold_uncertainty_score":0.54102886},"labels":[],"label_agreement":null},{"id":"W4200326660","doi":"10.7717/peerj.12579","title":"Preclinical models of acute liver failure: a comprehensive review","year":2021,"lang":"en","type":"review","venue":"PeerJ","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canada Research Chairs","keywords":"Medicine; Liver failure; Intensive care medicine; Disease; Liver disease; Pathophysiology; Bioinformatics; Pathology; Internal medicine; Biology","score_opus":0.49553420958325695,"score_gpt":0.5471045929467134,"score_spread":0.051570383363456485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200326660","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000062048807,0.9935446,0.00012036486,0.00029639096,0.0012856743,0.0022668638,0.0005481561,0.00008985778,0.0018418994],"genre_scores_gemma":[0.000011798395,0.995782,0.00041727116,0.0014365801,0.00038367134,0.00042702348,0.00042230848,0.00006616851,0.0010531496],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9946023,0.0025114731,0.0013971372,0.0007051484,0.000316719,0.00046720097],"domain_scores_gemma":[0.99671733,0.0011287292,0.0008939781,0.0005834817,0.00042001635,0.00025643702],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0010232466,0.0006014865,0.0034764914,0.00014507535,0.00015561172,0.000016188196,0.0005511737,0.0016028223,0.0017265293],"category_scores_gemma":[0.00015513001,0.00054078904,0.0015047614,0.0005343032,0.00020543592,0.00013899739,0.00029592295,0.0030308783,0.00040438178],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017433114,0.000268405,8.328862e-7,0.08609685,0.001963214,0.00011927259,0.000083865016,0.0000093986455,0.000011272722,0.00060991885,0.021240842,0.8895787],"study_design_scores_gemma":[0.0003250832,0.00007369799,4.5153e-7,0.02389387,0.007857564,0.00024823198,0.0000045723073,0.00018054932,0.00006205402,0.00015313075,0.96674424,0.00045652845],"about_ca_topic_score_codex":0.000019734152,"about_ca_topic_score_gemma":0.0000070655233,"teacher_disagreement_score":0.9455034,"about_ca_system_score_codex":0.00011572241,"about_ca_system_score_gemma":0.00055210374,"threshold_uncertainty_score":0.99970436},"labels":[],"label_agreement":null},{"id":"W4200385343","doi":"10.21203/rs.3.rs-1157913/v1","title":"Liver Enzymes After Acetaminophen Error in Critically Ill Children: A Cohort Study","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; Women's College Hospital; University of Toronto","funders":"Groupe canadien de recherche en soins intensifs","keywords":"Critically ill; Acetaminophen; Medicine; Liver enzyme; Cohort; Cohort study; Intensive care medicine; Internal medicine; Pharmacology","score_opus":0.17914394671281395,"score_gpt":0.4990142801751683,"score_spread":0.3198703334623544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200385343","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9836218,0.003611558,0.000030620184,0.0009340271,0.0010286074,0.007458185,0.00022391429,0.00014153478,0.002949752],"genre_scores_gemma":[0.99164915,0.00075886433,0.00014080928,0.00085842446,0.00067411485,0.004545837,0.00018560173,0.00008503091,0.0011021751],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.986995,0.007977786,0.0007595196,0.001546848,0.0012640398,0.0014568064],"domain_scores_gemma":[0.9956826,0.00092373724,0.0001075632,0.00095742877,0.0018216429,0.0005070287],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0067097326,0.00057121133,0.0008689773,0.00083193573,0.0004506949,0.0002496687,0.0008258944,0.0018436016,0.0047944146],"category_scores_gemma":[0.0018379173,0.0006009582,0.00030181085,0.0007723841,0.00043998493,0.00020861764,0.0021896514,0.011400207,0.0004543322],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00075349904,0.004352184,0.97490907,0.00085092784,0.0006059719,0.0021318838,0.0057201968,0.0002677698,0.00045878874,0.00012800393,0.0006254756,0.009196248],"study_design_scores_gemma":[0.0016068808,0.00043434266,0.98619264,0.00037174879,0.00014605922,0.00003449113,0.0020246743,0.0012885429,0.0047342274,0.00030849528,0.0021734424,0.00068447593],"about_ca_topic_score_codex":0.0019585541,"about_ca_topic_score_gemma":0.0023824305,"teacher_disagreement_score":0.011283569,"about_ca_system_score_codex":0.00070903084,"about_ca_system_score_gemma":0.0007872915,"threshold_uncertainty_score":0.99964416},"labels":[],"label_agreement":null},{"id":"W4206301278","doi":"10.1007/s42452-021-04859-z","title":"Hepatoprotective activity of the ethanolic extract of Morus indica roots from Indian Bodo tribes","year":2022,"lang":"en","type":"article","venue":"SN Applied Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Department of Science and Technology, Ministry of Science and Technology, India","keywords":"Antioxidant; Traditional medicine; Lipid peroxidation; Chemistry; Pharmacology; Bilirubin; CCL4; Biochemistry; Biology; Medicine; Carbon tetrachloride; Internal medicine","score_opus":0.12127972876208096,"score_gpt":0.39535800272967103,"score_spread":0.2740782739675901,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206301278","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98822206,0.00009243448,0.00004636215,0.00038332824,0.00078482187,0.000916774,0.00024317781,0.000035391018,0.009275643],"genre_scores_gemma":[0.9992676,0.0000150816995,0.000067132365,0.000266683,0.00007479896,0.0002445117,0.0000029846494,0.000009112142,0.000052122577],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99766433,0.0007812346,0.00030021172,0.00038690813,0.0005250977,0.00034219096],"domain_scores_gemma":[0.99871093,0.00043695082,0.0005041952,0.00023201924,0.00003142599,0.00008448276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019233766,0.000168266,0.0002966528,0.00019246536,0.001217383,0.000013564254,0.00079763256,0.00020624425,0.00081931864],"category_scores_gemma":[0.00007616261,0.00013498862,0.00012345366,0.0011539776,0.00089526625,0.00010837026,0.00032621252,0.0012868904,0.000010576367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028589397,0.0004556624,0.011402297,0.000026483618,0.000085104366,0.0000029351481,0.004782505,0.0011541328,0.9238488,0.001358342,0.00006167866,0.05653618],"study_design_scores_gemma":[0.0005726893,0.00014258723,0.031421557,0.0000069642033,0.000039768944,0.000005082021,0.0010247099,0.0005555638,0.9552402,0.0078050243,0.0030222123,0.00016365407],"about_ca_topic_score_codex":0.0008009063,"about_ca_topic_score_gemma":0.0001915423,"teacher_disagreement_score":0.056372523,"about_ca_system_score_codex":0.00009608311,"about_ca_system_score_gemma":0.0003210169,"threshold_uncertainty_score":0.93632483},"labels":[],"label_agreement":null},{"id":"W4206737985","doi":"10.1001/jama.288.23.2967","title":"Update: Fatal and Severe Liver Injuries Associated With Rifampin and Pyrazinamide Treatment for Latent Tuberculosis Infection","year":2002,"lang":"en","type":"article","venue":"JAMA","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Health Canada; Centers for Disease Control and Prevention; Washington State University; Kaiser Permanente","keywords":"Medicine; Pyrazinamide; Tuberculosis; Latent tuberculosis; Rifampicin; Internal medicine; Mycobacterium tuberculosis; Pathology","score_opus":0.09098552226784327,"score_gpt":0.35087458330392857,"score_spread":0.2598890610360853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206737985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99655133,0.0004033736,0.000056662906,0.0012002068,0.00020047901,0.00077178463,0.00014950732,0.00010086,0.0005657913],"genre_scores_gemma":[0.9964378,0.0019339627,0.00007575299,0.00059085625,0.00012397602,0.00020178838,0.00005353503,0.000019130986,0.00056318333],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9990609,0.00017554418,0.00015894431,0.00027179634,0.00007248667,0.00026028548],"domain_scores_gemma":[0.9994699,0.00019016434,0.000070257985,0.00007940432,0.00007002213,0.00012025581],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002345684,0.00019630376,0.00020465537,0.00008014333,0.00041188076,0.00005600523,0.000031760675,0.00037165254,0.00015405845],"category_scores_gemma":[0.000063800995,0.0001643437,0.000044452554,0.000116206356,0.00012175578,0.0002610313,0.000027044298,0.00029597367,0.00002152836],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021182646,0.0016541994,0.3187842,0.0002800925,0.0017798614,0.000050261468,0.005915948,0.00027394012,0.012452187,0.0011657409,0.004366712,0.6511586],"study_design_scores_gemma":[0.026783329,0.005492658,0.51647043,0.00019652402,0.0017776425,0.0003083555,0.00021205997,0.05590475,0.18311764,0.0015066835,0.20656677,0.0016631576],"about_ca_topic_score_codex":0.0001882397,"about_ca_topic_score_gemma":0.000508001,"teacher_disagreement_score":0.6494954,"about_ca_system_score_codex":0.00014239782,"about_ca_system_score_gemma":0.000012310542,"threshold_uncertainty_score":0.6701741},"labels":[],"label_agreement":null},{"id":"W4210620339","doi":"10.1016/j.biopha.2022.112673","title":"Investigations of the antipyretic effect and safety of Prasachandaeng, a traditional remedy from Thailand national list of essential medicines","year":2022,"lang":"en","type":"article","venue":"Biomedicine & Pharmacotherapy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Antipyretic; Medicine; Acetaminophen; Histopathology; CYP2E1; Liver function; Pharmacology; Liver injury; Kidney; Traditional medicine; Internal medicine; Metabolism; Cytochrome P450; Analgesic; Pathology","score_opus":0.08223916363122132,"score_gpt":0.38948878593803465,"score_spread":0.30724962230681335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210620339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990617,0.001148276,0.00011389469,0.0038378723,0.0015266921,0.0008762014,0.0012558408,0.00002170918,0.00060255855],"genre_scores_gemma":[0.9976586,0.00038624412,0.00005740677,0.0011544288,0.000433823,0.000090856876,0.0001370027,0.000016899467,0.00006473251],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997389,0.0009788253,0.0005994725,0.00023464857,0.0006321282,0.0001659136],"domain_scores_gemma":[0.9982314,0.00088670885,0.0005152924,0.0001275435,0.00013682753,0.00010223553],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0014982263,0.00018000168,0.00039373696,0.00022192381,0.00032798317,0.0000026376554,0.00025414373,0.000111685484,0.0020915684],"category_scores_gemma":[0.00010436234,0.00013672037,0.000110322035,0.0005635081,0.00096688647,0.00006694238,0.000060317852,0.00054427737,6.1692305e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011752283,0.00035485328,0.03435202,0.00014583865,0.00035133338,0.0000019912422,0.0016659448,0.0001124143,0.9544037,0.00045114962,0.0027107098,0.0042747976],"study_design_scores_gemma":[0.010888832,0.0009303082,0.03457883,0.00012050428,0.00038641194,0.000040389674,0.00015387178,0.0034129787,0.9107301,0.0022555436,0.03629406,0.00020812346],"about_ca_topic_score_codex":0.00019323548,"about_ca_topic_score_gemma":0.000014170681,"teacher_disagreement_score":0.04367358,"about_ca_system_score_codex":0.000054369422,"about_ca_system_score_gemma":0.00021879068,"threshold_uncertainty_score":0.99882066},"labels":[],"label_agreement":null},{"id":"W4210858469","doi":"10.4103/sjg.sjg_406_21","title":"N-acetylcysteine for non-acetaminophen induced acute liver failure","year":2022,"lang":"en","type":"review","venue":"Saudi Journal of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"","keywords":"Acetylcysteine; Medicine; Acetaminophen; Intensive care medicine; Liver failure; Adverse effect; Prospective cohort study; Clinical trial; acetaminophen overdose; Pharmacology; Internal medicine; Antioxidant","score_opus":0.1904195202292436,"score_gpt":0.4403089932380174,"score_spread":0.24988947300877382,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210858469","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009744746,0.9692901,0.0017394588,0.00081986125,0.013085007,0.0041430546,0.0007958823,0.00007960133,0.0003023281],"genre_scores_gemma":[0.0015111298,0.9937198,0.0008374866,0.0010367177,0.0018436078,0.00043320132,0.0001286755,0.00013009305,0.00035926572],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9942138,0.0021186047,0.0018340809,0.0005256039,0.00032013323,0.0009877757],"domain_scores_gemma":[0.9954245,0.00063703436,0.0029529785,0.00035884228,0.00023399784,0.0003926284],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0023447261,0.00077100715,0.0031503567,0.00076007127,0.00046258056,0.000033334793,0.0011012217,0.001258286,0.0015879285],"category_scores_gemma":[0.00015644959,0.00068879017,0.0016427926,0.00031406563,0.00016569605,0.00022035264,0.00032030974,0.004810385,0.000060784365],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040316554,0.0008102177,0.00009515883,0.010363257,0.008010176,0.00088131276,0.0005213509,0.000034195564,0.0011491468,0.000044540164,0.015095139,0.9589639],"study_design_scores_gemma":[0.0032966256,0.0057839546,0.000006107974,0.00067123584,0.0044646845,0.0055180406,0.000048459013,0.000038833994,0.00009514091,0.00004374033,0.97971046,0.0003227089],"about_ca_topic_score_codex":0.0000055022238,"about_ca_topic_score_gemma":0.000031107564,"teacher_disagreement_score":0.96461535,"about_ca_system_score_codex":0.0005232726,"about_ca_system_score_gemma":0.0004421568,"threshold_uncertainty_score":0.9995563},"labels":[],"label_agreement":null},{"id":"W4211175126","doi":"10.1016/s0140-6736(19)31894-x","title":"Acute liver failure","year":2019,"lang":"en","type":"review","venue":"The Lancet","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":809,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Genentech; Novo Nordisk; Sanofi; University of South Carolina; Southwestern Medical Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; Mallinckrodt Pharmaceuticals; U.S. Food and Drug Administration; Bristol-Myers Squibb","keywords":"Medicine; Liver failure; Liver transplantation; Cirrhosis; Liver injury; Liver disease; Chronic liver disease; Internal medicine; Intensive care medicine; Viral hepatitis; Autoimmune hepatitis; Gastroenterology; Hepatitis; Transplantation","score_opus":0.3953703379579782,"score_gpt":0.500046169497749,"score_spread":0.10467583153977084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4211175126","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00002189179,0.9809474,0.000017518889,0.00076134625,0.002485601,0.0015570124,0.00037245342,0.00016663838,0.013670157],"genre_scores_gemma":[0.00004586493,0.9883718,0.000046179706,0.0017881674,0.003523746,0.000222103,0.00010398534,0.000054352582,0.005843818],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973297,0.0012431479,0.00036540267,0.00036877207,0.00014710546,0.0005458489],"domain_scores_gemma":[0.99835753,0.00048903964,0.0003227814,0.00069964054,0.00003687606,0.00009412223],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0009734466,0.00041983876,0.0016874417,0.00008449111,0.0002999317,0.00004679686,0.0009912979,0.0011172171,0.0013983387],"category_scores_gemma":[0.000037465008,0.00026343975,0.00043894252,0.0002786477,0.00012016893,0.00007882214,0.00018288005,0.0032927291,0.008308733],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039932842,0.000039356084,0.0000030813453,0.00568977,0.00078469777,0.000032774766,0.0001603105,0.0000030272802,0.000010745828,0.0010265824,0.080578014,0.9116317],"study_design_scores_gemma":[0.00042568106,0.000033685963,0.0000013889586,0.0008095561,0.0021299939,0.00014414235,0.0000056462877,0.000039454837,0.000041090447,0.00015326316,0.99589187,0.00032425733],"about_ca_topic_score_codex":0.000011276387,"about_ca_topic_score_gemma":0.000017035176,"teacher_disagreement_score":0.91531384,"about_ca_system_score_codex":0.0001082246,"about_ca_system_score_gemma":0.00016189573,"threshold_uncertainty_score":0.99998176},"labels":[],"label_agreement":null},{"id":"W4213036259","doi":"10.2196/32415","title":"Correction: Predicting Antituberculosis Drug–Induced Liver Injury Using an Interpretable Machine Learning Method: Model Development and Validation Study","year":2021,"lang":"en","type":"article","venue":"JMIR Medical Informatics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Computer science; Liver injury; Drug development; Drug; Artificial intelligence; Machine learning; Medicine; Medical physics; Pharmacology","score_opus":0.13494374113960764,"score_gpt":0.44636736663227905,"score_spread":0.31142362549267144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213036259","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9712929,0.00003771408,0.025459092,0.000047869307,0.0011784846,0.00060382806,0.000006386765,0.00017793779,0.0011957452],"genre_scores_gemma":[0.9893283,0.00005852756,0.009346967,0.0006782239,0.00015223125,0.00008577937,0.00006272097,0.000023331035,0.00026389313],"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9971956,0.00088150264,0.0008080808,0.00024147538,0.00050806766,0.00036528645],"domain_scores_gemma":[0.99873275,0.00025641234,0.00027141423,0.0001620841,0.00018465907,0.00039270366],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0025552567,0.00025178352,0.00034045047,0.00016912041,0.000789764,0.00009250453,0.00015785261,0.00044466235,0.000362839],"category_scores_gemma":[0.00033853416,0.0002516169,0.000050161507,0.00035557026,0.000054830478,0.00082014455,0.0002503392,0.0019300288,0.000019611709],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039769898,0.0030607875,0.058272235,0.00075223675,0.0007219463,0.000094581665,0.20186721,0.030554218,0.012987229,0.00010873509,0.0003354056,0.6908477],"study_design_scores_gemma":[0.0007699224,0.00012229991,0.00031301085,0.00009118969,0.00010362813,0.00011404835,0.005657726,0.9349432,0.055527207,0.000019525363,0.0020752656,0.0002630042],"about_ca_topic_score_codex":0.00009821712,"about_ca_topic_score_gemma":0.00011139412,"teacher_disagreement_score":0.90438896,"about_ca_system_score_codex":0.00016445431,"about_ca_system_score_gemma":0.0003655396,"threshold_uncertainty_score":0.9999936},"labels":[],"label_agreement":null},{"id":"W4214889038","doi":"10.22541/au.164630374.47492079/v1","title":"Cloxacillin-induced acute vanishing bile duct syndrome: a case study and literature review","year":2022,"lang":"en","type":"preprint","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Oakville-Trafalgar Memorial Hospital; HalTech; University of Saskatchewan","funders":"","keywords":"Cloxacillin; Cholestasis; Medicine; Gastroenterology; Internal medicine; Liver transplantation; Liver biopsy; Liver injury; Biopsy; Antibiotics; Transplantation; Penicillin; Chemistry","score_opus":0.16628576704421116,"score_gpt":0.4692646435363268,"score_spread":0.30297887649211563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4214889038","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9597246,0.024302978,0.000021956816,0.0013078041,0.004701883,0.0066557303,0.00045686925,0.00042778937,0.00240036],"genre_scores_gemma":[0.9525281,0.038295887,0.00019647632,0.0042615407,0.00032445346,0.0019368257,0.00021512253,0.00009250507,0.0021490434],"study_design_codex":"case_report","study_design_gemma":"case_report","domain_scores_codex":[0.993595,0.0029639325,0.0009348201,0.001438586,0.0004072073,0.00066045584],"domain_scores_gemma":[0.99768674,0.00036221935,0.0004974003,0.00084713014,0.00018413538,0.0004223566],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0032494096,0.000822156,0.0011839638,0.0003305814,0.0012127022,0.0002346218,0.00056014536,0.001223538,0.0034246487],"category_scores_gemma":[0.00014316541,0.0007848202,0.00032645796,0.00067774864,0.00007832929,0.00027353692,0.0019496148,0.0093478225,0.00005699587],"study_design_candidate":"case_report","study_design_consensus":"case_report","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008812683,0.008542875,0.0065049776,0.033653043,0.012492486,0.690791,0.041897647,0.00045791795,0.01401614,0.00053203304,0.022336602,0.16789402],"study_design_scores_gemma":[0.014110012,0.0071564605,0.0010389726,0.0108505245,0.0206843,0.48870596,0.016875274,0.0057404195,0.010042139,0.0041876887,0.40957448,0.011033763],"about_ca_topic_score_codex":0.00042219582,"about_ca_topic_score_gemma":0.000152133,"teacher_disagreement_score":0.38723788,"about_ca_system_score_codex":0.00027564674,"about_ca_system_score_gemma":0.00025121265,"threshold_uncertainty_score":0.9994603},"labels":[],"label_agreement":null},{"id":"W4224224089","doi":"10.1503/cmaj.210703","title":"Treating acetaminophen overdose","year":2022,"lang":"en","type":"article","venue":"Canadian Medical Association Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; University of Calgary; Queen's University; Alberta Health Services","funders":"","keywords":"Acetylcysteine; Antidote; acetaminophen overdose; Acetaminophen; Medicine; Drug overdose; Presentation (obstetrics); Emergency medicine; Medical emergency; Anesthesia; Intensive care medicine; Poison control; Surgery; Internal medicine; Toxicity; Chemistry","score_opus":0.05623704988362758,"score_gpt":0.36735493020715204,"score_spread":0.31111788032352444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224224089","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91266674,0.0002729783,0.00006011984,0.034975324,0.0067253346,0.0002887678,0.00013008385,0.000071755916,0.044808924],"genre_scores_gemma":[0.96744907,0.00005856237,0.00003393382,0.027217465,0.0018312364,0.000043715674,0.000016028653,0.000017384538,0.003332603],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966954,0.0012927906,0.00036541253,0.00015837126,0.00091093266,0.00057707186],"domain_scores_gemma":[0.9978839,0.00030388866,0.0002471829,0.00006984645,0.00012542446,0.001369744],"candidate_categories":["sts","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004147129,0.00011994496,0.00017419878,0.0002017185,0.002099349,0.000049643317,0.00028975593,0.0004183443,0.045012545],"category_scores_gemma":[0.0009600686,0.00013210707,0.00010915742,0.00032053262,0.000030051753,0.00012371081,0.000048307407,0.0039025885,0.00027581348],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009644801,0.00027063256,0.15382217,0.000018207022,0.0005383099,0.0017604311,0.0037596473,0.001107154,0.0013127245,0.002045529,0.3098811,0.52538764],"study_design_scores_gemma":[0.001124063,0.00007376339,0.004194187,0.0000050254866,0.00003333445,0.00060442113,0.00062891643,0.0020253654,0.00023987314,0.00048780316,0.9904212,0.00016206862],"about_ca_topic_score_codex":0.002063398,"about_ca_topic_score_gemma":0.0052125794,"teacher_disagreement_score":0.6805401,"about_ca_system_score_codex":0.002672131,"about_ca_system_score_gemma":0.0019905653,"threshold_uncertainty_score":0.9991998},"labels":[],"label_agreement":null},{"id":"W4224281239","doi":"10.1503/cmaj.210842","title":"Impact of acetaminophen product labelling changes in Canada on hospital admissions for accidental acetaminophen overdose: a population-based study","year":2022,"lang":"en","type":"article","venue":"Canadian Medical Association Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"Ontario Drug Policy Research Network; Toronto Rehabilitation Institute; University of Toronto; University Health Network","funders":"","keywords":"Accidental; Medicine; Acetaminophen; Emergency medicine; Population; Drug overdose; Medical emergency; acetaminophen overdose; Intensive care unit; Poison control; Intensive care medicine; Anesthesia; Environmental health; Acetylcysteine","score_opus":0.04549493568941549,"score_gpt":0.37181421846385304,"score_spread":0.32631928277443756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224281239","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98924416,0.000050992257,0.0000039451947,0.0073240534,0.0019103786,0.0010328675,0.0003541358,0.000009654735,0.00006982173],"genre_scores_gemma":[0.9970077,0.000007291293,0.000013218544,0.0020483998,0.000578598,0.00015857714,0.00006185762,0.000020323874,0.000104025305],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9968729,0.0009164484,0.00048937387,0.00023883782,0.00092945487,0.0005529936],"domain_scores_gemma":[0.9977144,0.00054875674,0.00043140704,0.00010274069,0.00017062736,0.0010320583],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0023745797,0.00017477556,0.00031833898,0.00032203965,0.00076730194,0.000021663096,0.00029588272,0.00018707389,0.0053016213],"category_scores_gemma":[0.001741734,0.00017680043,0.000112820315,0.00039547007,0.000009323033,0.000075744676,0.000027857184,0.0018775181,0.000003208193],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":true,"about_ca_system_consensus":true,"study_design_scores_codex":[0.00013298941,0.0004406615,0.9748729,0.000010911377,0.00019085455,0.000105057865,0.0007623257,0.006819478,0.00012751098,0.000011446265,0.003880471,0.012645429],"study_design_scores_gemma":[0.0047286847,0.0012826911,0.97544,0.000034451223,0.00008684518,0.00002639064,0.00186074,0.0061926935,0.00043226965,0.00008012055,0.009487161,0.00034790486],"about_ca_topic_score_codex":0.7055615,"about_ca_topic_score_gemma":0.95603037,"teacher_disagreement_score":0.25046885,"about_ca_system_score_codex":0.0100661665,"about_ca_system_score_gemma":0.0125695625,"threshold_uncertainty_score":0.9956077},"labels":[],"label_agreement":null},{"id":"W4224990437","doi":"10.21203/rs.3.rs-1557481/v1","title":"Mapping the incidence of drug-induced liver injury worldwide: a systematic review and meta-analysis","year":2022,"lang":"en","type":"review","venue":"Research Square","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Natural Science Foundation of China","keywords":"Meta-analysis; Drug; Liver injury; Incidence (geometry); Medicine; Internal medicine; Pharmacology; Mathematics","score_opus":0.5637762485993909,"score_gpt":0.5544329368371926,"score_spread":0.00934331176219827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224990437","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000022110298,0.9882051,0.000006329171,0.00042501144,0.00012206934,0.010258831,0.00033616333,0.000047928144,0.00057646434],"genre_scores_gemma":[0.0013378893,0.9891457,0.00001285707,0.00046197436,0.00006279543,0.0071358797,0.000059170787,0.000053589356,0.0017301424],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.9710334,0.024509883,0.0016762161,0.00080691965,0.0012252092,0.00074834767],"domain_scores_gemma":[0.98967755,0.0073657217,0.001112935,0.0011865018,0.00039696737,0.00026032407],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.023232887,0.0005888843,0.006235033,0.0014603193,0.0011547128,0.000070316055,0.0013267897,0.00049376127,0.005038659],"category_scores_gemma":[0.0020731813,0.00037068155,0.0026527334,0.006414386,0.000336649,0.000154372,0.0010005231,0.005626147,0.00013273983],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008566263,0.000106058964,0.0000020890993,0.91130733,0.06601464,0.00003805392,0.00060497824,0.0000016685369,0.000003833858,0.00017577324,0.00058274873,0.021154236],"study_design_scores_gemma":[0.00007668454,0.00007672765,0.0000018004525,0.017791547,0.46790177,0.00004664877,0.00028041017,0.000047680256,0.000019005567,0.00006674172,0.51329094,0.0004000492],"about_ca_topic_score_codex":0.00029309106,"about_ca_topic_score_gemma":0.00012073245,"teacher_disagreement_score":0.8935158,"about_ca_system_score_codex":0.0003638689,"about_ca_system_score_gemma":0.0005143282,"threshold_uncertainty_score":0.99987453},"labels":[],"label_agreement":null},{"id":"W4229376362","doi":"10.1503/cmaj.220651","title":"Correction to “Impact of acetaminophen product labelling changes in Canada on hospital admissions for accidental acetaminophen overdose: a population-based study”","year":2022,"lang":"en","type":"erratum","venue":"Canadian Medical Association Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Acetaminophen; Labelling; Accidental; Medicine; acetaminophen overdose; Population; Medical emergency; Emergency medicine; Anesthesia; Environmental health; Chemistry","score_opus":0.04141479295399546,"score_gpt":0.3698284096535319,"score_spread":0.32841361669953645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4229376362","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8577605,0.00020543573,0.0000105835015,0.014038365,0.12175648,0.0037035933,0.0014452487,0.00003250906,0.0010472672],"genre_scores_gemma":[0.9823928,0.00005615308,0.000013194494,0.0038758637,0.0044929995,0.00034758728,0.00057087,0.000069021655,0.0081815375],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.9950358,0.0012291039,0.00085426803,0.00048436702,0.0015347238,0.0008617107],"domain_scores_gemma":[0.9956249,0.00091373187,0.00091352325,0.0001891766,0.00038936074,0.0019693074],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0028074787,0.00040627277,0.0007229497,0.00081891805,0.00080541224,0.00005183492,0.00049553264,0.0007900742,0.009452438],"category_scores_gemma":[0.006676351,0.0004231033,0.00023117555,0.00069313514,0.000011578969,0.00009413164,0.000042727534,0.0057414914,0.000010800751],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":true,"about_ca_system_consensus":true,"study_design_scores_codex":[0.00018978605,0.0003892615,0.25920048,0.000045492536,0.00039942158,0.00014467312,0.00079103623,0.0050661955,0.000021586739,0.000002232845,0.71540844,0.018341407],"study_design_scores_gemma":[0.004606411,0.0027909349,0.49423677,0.000543085,0.00036815723,0.000046440124,0.001943023,0.008771835,0.00022389696,0.000040126328,0.48526934,0.0011599893],"about_ca_topic_score_codex":0.8506628,"about_ca_topic_score_gemma":0.99096453,"teacher_disagreement_score":0.23503628,"about_ca_system_score_codex":0.024262158,"about_ca_system_score_gemma":0.033607256,"threshold_uncertainty_score":0.9998221},"labels":[],"label_agreement":null},{"id":"W4232187265","doi":"10.2174/157016108784912019","title":"Amiodarone Hepatotoxicity","year":2008,"lang":"en","type":"review","venue":"Current Vascular Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Amiodarone; Medicine; Discontinuation; Drug; Intensive care medicine; Adverse effect; Toxicity; Incidence (geometry); Drug toxicity; Pharmacology; Internal medicine","score_opus":0.33181310272324477,"score_gpt":0.5187338005798461,"score_spread":0.18692069785660131,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4232187265","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002620613,0.9685898,0.00024303762,0.00004533964,0.023479639,0.004454335,0.0003657877,0.0006856203,0.0018744149],"genre_scores_gemma":[0.000097815166,0.99179715,0.00005775968,0.00048619797,0.0041704997,0.002136512,0.0006514602,0.0002460848,0.00035652076],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9884672,0.005398218,0.0018944553,0.0017976102,0.00058727525,0.0018552337],"domain_scores_gemma":[0.9960315,0.0008231562,0.0011336547,0.00081493397,0.00023379219,0.000962942],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"category_scores_codex":[0.0013708641,0.0017543552,0.0040075923,0.0009667432,0.0011344583,0.000046919715,0.0014949895,0.0029361423,0.003824167],"category_scores_gemma":[0.00013688437,0.0016918293,0.002759028,0.0012930227,0.00076824427,0.00028093116,0.000596236,0.008208327,0.005686742],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039453334,0.0011248891,0.000016473834,0.0089147715,0.0017886489,0.00017684561,0.0001443125,0.000019775427,0.00007743576,0.00013402368,0.03320641,0.95435697],"study_design_scores_gemma":[0.001776333,0.00011714702,0.000004330536,0.0010659831,0.003562773,0.0005771471,0.0000049791943,0.00019731898,0.0004133745,0.000074668984,0.9906521,0.0015538549],"about_ca_topic_score_codex":0.000024964182,"about_ca_topic_score_gemma":0.000006402346,"teacher_disagreement_score":0.9574457,"about_ca_system_score_codex":0.0009629453,"about_ca_system_score_gemma":0.0011452662,"threshold_uncertainty_score":0.99952024},"labels":[],"label_agreement":null},{"id":"W4233034411","doi":"10.14740/jmc3108w","title":"A Delayed Case of Black Cohosh Associated Drug-Induced Liver Injury","year":2018,"lang":"en","type":"article","venue":"Journal of Medical Cases","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Black cohosh; Medicine; Liver injury; Drug; Acetaminophen; Culprit; Over-the-counter; Medical prescription; Traditional medicine; Internal medicine; Pharmacology","score_opus":0.14014240915843684,"score_gpt":0.45205078963049533,"score_spread":0.3119083804720585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4233034411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951329,0.00020153783,0.000076318065,0.0013785652,0.002121584,0.00020760446,0.000051862364,0.000026448331,0.00080314686],"genre_scores_gemma":[0.9965294,0.00029427445,0.00005285213,0.0016599592,0.0013063003,0.0000039265474,0.0000027820993,0.000018758737,0.00013174217],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967306,0.001130556,0.0009160639,0.0001644821,0.00070216705,0.00035608828],"domain_scores_gemma":[0.9966258,0.0011491263,0.0008480036,0.00013344512,0.00066411647,0.00057953823],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.003990507,0.00019481716,0.00049795286,0.00022850347,0.00022092507,0.000014621668,0.0003206357,0.00073860947,0.0033115821],"category_scores_gemma":[0.0032284167,0.00016362095,0.00022886427,0.0003585858,0.0005083007,0.00017548543,0.000087132,0.0017985885,0.000077892175],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012756781,0.009754157,0.01255115,0.0006173729,0.005012874,0.15208344,0.018754613,0.00004405913,0.14894518,0.0014462207,0.25672933,0.38130483],"study_design_scores_gemma":[0.0147815,0.011146952,0.002811446,0.00089752045,0.00210704,0.07242726,0.003318389,0.013497683,0.76671714,0.0014029525,0.109639116,0.0012530261],"about_ca_topic_score_codex":0.00039631833,"about_ca_topic_score_gemma":0.00053191435,"teacher_disagreement_score":0.6177719,"about_ca_system_score_codex":0.00013287911,"about_ca_system_score_gemma":0.00046978795,"threshold_uncertainty_score":0.99759954},"labels":[],"label_agreement":null},{"id":"W4236340443","doi":"10.1007/s40278-019-62556-8","title":"Hepatotoxicity with tocilizumab: Canadian and NZ warnings","year":2019,"lang":"en","type":"article","venue":"Reactions Weekly","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Tocilizumab; Medicine; Pharmacology; Internal medicine; Rheumatoid arthritis","score_opus":0.06592762606951606,"score_gpt":0.36019245171184705,"score_spread":0.294264825642331,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4236340443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.943959,0.000058409525,0.000038423208,0.0019038607,0.00062939496,0.0007262141,0.000037859063,0.00014794976,0.052498877],"genre_scores_gemma":[0.98966336,0.00009159818,0.000106430845,0.0009910683,0.0001328258,0.000081505765,0.000018745344,0.000027433567,0.008887018],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986082,0.0002039597,0.00021105201,0.00037052517,0.000130882,0.0004754087],"domain_scores_gemma":[0.99897426,0.00015857932,0.000101714104,0.00022396064,0.00008599199,0.00045548586],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00043372155,0.00021069382,0.00021902932,0.00023956601,0.00055287,0.000042139316,0.00011855501,0.0003968781,0.0012613676],"category_scores_gemma":[0.00004341248,0.00019967592,0.00005185438,0.00031173867,0.00011467072,0.00028202822,0.000027266335,0.0011116412,0.00087502116],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010870085,0.00067296106,0.70323867,0.00043424743,0.0008356887,0.00017198791,0.005296729,0.0008923925,0.18351826,0.013378538,0.008898989,0.08157453],"study_design_scores_gemma":[0.0014556329,0.0003275816,0.04050594,0.00004083926,0.00008599306,0.00030892465,0.00038301395,0.0031824615,0.016357746,0.00049268274,0.9363968,0.00046243248],"about_ca_topic_score_codex":0.045406803,"about_ca_topic_score_gemma":0.041095246,"teacher_disagreement_score":0.92749774,"about_ca_system_score_codex":0.0002829192,"about_ca_system_score_gemma":0.0002833186,"threshold_uncertainty_score":0.9999029},"labels":[],"label_agreement":null},{"id":"W4240089460","doi":"10.3410/f.1166605.627617","title":"Faculty Opinions recommendation of T-type calcium channel inhibition underlies the analgesic effects of the endogenous lipoamino acids.","year":2009,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Analgesic; Endogeny; Calcium channel; Pharmacology; Chemistry; Analgesic agents; Calcium; Medicine; Biochemistry; Organic chemistry","score_opus":0.13518420912035511,"score_gpt":0.42621242821009586,"score_spread":0.29102821908974075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240089460","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000038967042,0.0017289803,0.000029885,0.11217637,0.0030582068,0.002933901,0.87991273,0.000036358353,0.00008462276],"genre_scores_gemma":[0.0032717132,0.0009313724,0.000033593034,0.007772804,0.00044313716,0.0002031793,0.98692846,0.000023895058,0.00039185525],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99417853,0.0023381454,0.0014765875,0.000542887,0.0010299617,0.0004338941],"domain_scores_gemma":[0.9927076,0.0005617323,0.002069867,0.001184347,0.003272042,0.00020442849],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0021950433,0.00056279683,0.0008944687,0.00028947764,0.0007092858,0.00006131411,0.0014879517,0.0013645181,0.00018636255],"category_scores_gemma":[0.004532619,0.00030938958,0.00071209,0.002473139,0.0007013105,0.00024769746,0.00041424853,0.002605734,0.00003194961],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000473634,0.0006403543,0.0000058825667,0.006634516,0.00026278148,4.357713e-7,0.0004560652,0.0000018520732,0.00016167689,0.0002020326,0.9875343,0.0040527424],"study_design_scores_gemma":[0.0008164078,0.00026957507,0.001299483,0.0045427475,0.0005578638,0.000067154426,0.000047790094,0.00002725074,0.004978746,0.00016823561,0.98693526,0.00028947066],"about_ca_topic_score_codex":0.00009061029,"about_ca_topic_score_gemma":0.000016829998,"teacher_disagreement_score":0.107015744,"about_ca_system_score_codex":0.00016930644,"about_ca_system_score_gemma":0.0005385117,"threshold_uncertainty_score":0.9999358},"labels":[],"label_agreement":null},{"id":"W4240112120","doi":"10.2165/00128413-200615420-00058","title":"Health Canada is warning against the use of the Triaminic Vapour Patch, which contains camphor, eucalyptus oil and menthol,","year":2006,"lang":"en","type":"article","venue":"Inpharma Weekly","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Menthol; Camphor; Medicine; Eucalyptus oil; Eucalyptus; Pharmacy; Traditional medicine; Environmental health; Toxicology; Botany; Organic chemistry; Family medicine; Biology; Chemistry","score_opus":0.13088043866062968,"score_gpt":0.3714705709660939,"score_spread":0.24059013230546425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240112120","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96122944,0.0009956034,0.000024371984,0.03379128,0.0018505352,0.00046973382,0.00030183487,0.000049682105,0.0012875022],"genre_scores_gemma":[0.97781944,0.000799648,0.000028435736,0.018576453,0.00030346276,0.00007533656,0.00002038171,0.000030465133,0.002346375],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99648947,0.001546575,0.0006699014,0.0003578679,0.00034034866,0.00059583917],"domain_scores_gemma":[0.9980461,0.0007688885,0.00050574366,0.00032734335,0.0001669314,0.00018497925],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011739129,0.0002984962,0.00041159254,0.00006741342,0.0009972854,0.00004907115,0.00034699004,0.00024456135,0.00011432033],"category_scores_gemma":[0.00014793538,0.00020711382,0.00010540337,0.00046139746,0.00019874658,0.00016401257,0.00014584037,0.0013360473,0.000008834548],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012558796,0.0010625547,0.09715383,0.0006508197,0.0009655948,0.0000736683,0.008453926,0.0064805434,0.07233119,0.0007829038,0.40276676,0.4080223],"study_design_scores_gemma":[0.0029853138,0.00008633152,0.017030021,0.000062363746,0.0001395849,0.00003646643,0.00037734222,0.0071555446,0.03109847,0.00008758133,0.9405919,0.00034908118],"about_ca_topic_score_codex":0.3673585,"about_ca_topic_score_gemma":0.34519154,"teacher_disagreement_score":0.5378251,"about_ca_system_score_codex":0.0003241299,"about_ca_system_score_gemma":0.0010931339,"threshold_uncertainty_score":0.84458566},"labels":[],"label_agreement":null},{"id":"W4241320413","doi":"10.1002/14651858.cd012123","title":"N-acetylcysteine for non-paracetamol (acetaminophen)-related acute liver failure","year":2016,"lang":"en","type":"article","venue":"Cochrane Database of Systematic Reviews","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Vancouver General Hospital; Fraser Health","funders":"","keywords":"Acetylcysteine; Acetaminophen; Liver failure; Medicine; Placebo; acetaminophen overdose; Intervention (counseling); Protocol (science); Anesthesia; Intensive care medicine; Internal medicine; Alternative medicine; Psychiatry; Chemistry; Antioxidant","score_opus":0.15559689364335816,"score_gpt":0.4267984864479254,"score_spread":0.27120159280456724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4241320413","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.37325484,0.29006782,0.15860924,0.0059264884,0.0145801995,0.13713378,0.0125852,0.0010115175,0.0068309386],"genre_scores_gemma":[0.8610641,0.10766974,0.007356995,0.0009940112,0.00070997584,0.010439116,0.0007085569,0.00019267833,0.010864855],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99469095,0.0016345106,0.0022346233,0.00058125216,0.00031336493,0.00054530974],"domain_scores_gemma":[0.9952821,0.0015229739,0.0015288085,0.0010773612,0.00032009577,0.00026863386],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0056121885,0.0005054112,0.0021147693,0.00019234102,0.00024198432,0.00002070573,0.00062013615,0.0004569937,0.0010564146],"category_scores_gemma":[0.0015107892,0.0003145608,0.000536417,0.00037429132,0.00019383115,0.00044476247,0.00012385046,0.00040415308,0.0014398033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025387853,0.00033519382,0.00004751527,0.33805647,0.000833667,0.000036860416,0.0005939444,0.000003942669,0.64120406,0.0014026645,0.012798721,0.0044330703],"study_design_scores_gemma":[0.018228577,0.001127641,0.000051311374,0.29801348,0.008218031,0.00090297655,0.0003026064,0.0050942353,0.54686254,0.00037485655,0.11854805,0.0022757088],"about_ca_topic_score_codex":0.000012933599,"about_ca_topic_score_gemma":0.000018334425,"teacher_disagreement_score":0.48780924,"about_ca_system_score_codex":0.000111320274,"about_ca_system_score_gemma":0.00008055367,"threshold_uncertainty_score":0.9999306},"labels":[],"label_agreement":null},{"id":"W4246197441","doi":"10.1515/iupac.73.0049","title":"Anisidine Value (ANV)","year":2016,"lang":"en","type":"dataset","venue":"IUPAC Standards Online","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Okanagan College","funders":"","keywords":"Table (database); Commission; Product (mathematics); Food science; Chemistry; Biochemistry; Value (mathematics); Human nutrition; Organic chemistry; Polymer science; Mathematics; Computer science; Political science; Data mining; Law; Statistics","score_opus":0.09018910511515228,"score_gpt":0.5310584952495244,"score_spread":0.44086939013437215,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4246197441","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011432726,0.00078457285,0.00015845397,0.0018913429,0.0064855013,0.0009440955,0.98774904,0.00024328261,0.00060043146],"genre_scores_gemma":[0.0004336789,0.0031947393,0.000037439302,0.0028508897,0.004006514,0.00015226108,0.987684,0.00008348473,0.0015569573],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99543947,0.00095419824,0.0008376444,0.0008934459,0.0009009013,0.00097431516],"domain_scores_gemma":[0.9972072,0.00042533234,0.00052159274,0.000841098,0.00048970734,0.0005150156],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0021942356,0.00081482995,0.0009619626,0.0003874118,0.00056222576,0.00006147326,0.00078168674,0.0023502167,0.019203668],"category_scores_gemma":[0.0007000811,0.0006813393,0.00035678333,0.00036258454,0.00034038344,0.00018834116,0.00028967264,0.003125039,0.00008253893],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006436496,0.00058181357,0.000018400458,0.0002460765,0.00036964283,0.00017086425,0.000030063668,0.000018209219,0.00094554527,0.00009944453,0.9812224,0.015653871],"study_design_scores_gemma":[0.0022845962,0.0003843545,0.000020059892,0.00021334001,0.0004079963,0.000079235986,0.000015810088,0.000046662175,0.004058323,0.0008993886,0.9907636,0.00082664296],"about_ca_topic_score_codex":0.00020692198,"about_ca_topic_score_gemma":0.0004710192,"teacher_disagreement_score":0.019121129,"about_ca_system_score_codex":0.00081782683,"about_ca_system_score_gemma":0.0009843871,"threshold_uncertainty_score":0.99956375},"labels":[],"label_agreement":null},{"id":"W4246240070","doi":"10.1080/714028806","title":"Case report and review of the role of late Nacetylcysteine administration in fulminant hepatic failure secondary to acetaminophen toxicity in infancy","year":2002,"lang":"en","type":"article","venue":"Clinical Intensive Care","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Western Ontario","funders":"","keywords":"Medicine; Acetaminophen; Fulminant hepatic failure; Metabolic acidosis; acetaminophen overdose; Toxicity; Encephalopathy; Fulminant; Anesthesia; Jaundice; Toxic encephalopathy; Pediatric intensive care unit; Intensive care medicine; Gastroenterology; Internal medicine; Acetylcysteine; Liver transplantation","score_opus":0.11877700470140136,"score_gpt":0.43414044860247436,"score_spread":0.315363443901073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4246240070","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98927665,0.0061418964,0.0000026605846,0.0021301094,0.00041998693,0.0011811204,0.00006584554,0.000009869331,0.00077184686],"genre_scores_gemma":[0.99364907,0.001588046,0.000046556444,0.004487804,0.000051862375,0.00006181093,0.000009930002,0.000010554941,0.00009439709],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972504,0.0008212376,0.0012763909,0.00032961063,0.000116744915,0.0002056316],"domain_scores_gemma":[0.9977968,0.00048831716,0.00045080035,0.0003066894,0.0008365478,0.00012087978],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010737651,0.0001679416,0.0006057514,0.00008464405,0.000057631765,0.0000040417963,0.00013887898,0.0003813857,0.00017934763],"category_scores_gemma":[0.004402847,0.0001361813,0.00014311494,0.00036522534,0.00021059113,0.000079897225,0.00013321625,0.0010873199,0.00000778781],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011454952,0.0013008867,0.6692468,0.015531458,0.00031608474,0.020480068,0.022232799,0.00011984128,0.04358269,0.00027607696,0.0029401118,0.2228277],"study_design_scores_gemma":[0.0112743685,0.005207607,0.17629436,0.026324397,0.0010894159,0.025884314,0.030835394,0.006003416,0.64402336,0.0013643545,0.06955923,0.002139765],"about_ca_topic_score_codex":0.000099758705,"about_ca_topic_score_gemma":0.0014735318,"teacher_disagreement_score":0.6004407,"about_ca_system_score_codex":0.000055496446,"about_ca_system_score_gemma":0.00009596343,"threshold_uncertainty_score":0.5553313},"labels":[],"label_agreement":null},{"id":"W4247429975","doi":"10.1139/apnm-2017-0668","title":"Hepatoprotective and antioxidant properties of the aqueous extract of <i>Olea europaea</i> leaves against Diclofenac-induced liver damages in mice","year":2018,"lang":"en","type":"article","venue":"Applied Physiology Nutrition and Metabolism","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":true,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Olea; Diclofenac; Damages; Antioxidant; Liver toxicity; Aqueous extract; Traditional medicine; Chemistry; Pig liver; Aqueous solution; Botany; Biology; Biochemistry; Medicine; Toxicity; Enzyme; Organic chemistry","score_opus":0.06503664315610512,"score_gpt":0.3185211807917765,"score_spread":0.25348453763567136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4247429975","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951803,0.0024793646,0.000010098131,0.00016925426,0.00034343972,0.001064983,0.00003119792,0.000028106097,0.0006932578],"genre_scores_gemma":[0.9956197,0.0032538637,0.00007079163,0.0006774548,0.00019821999,0.00013949967,0.0000029193056,0.000017217782,0.000020332118],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983048,0.00059688924,0.00038225477,0.0003473836,0.00009883893,0.00026982263],"domain_scores_gemma":[0.99927205,0.00010664346,0.00027050247,0.00016527808,0.00011650282,0.000069045855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004310654,0.00021949531,0.0004354226,0.00013869313,0.00023199129,0.000007204681,0.00015736542,0.00033983222,0.000016227525],"category_scores_gemma":[0.000049509406,0.00016801794,0.000065720415,0.00026946532,0.0009128457,0.000104591534,0.0001199267,0.00063995906,0.0000050296403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041429728,0.00040839994,0.0001791647,0.00021160694,0.000056736215,0.0000014651963,0.0013219663,0.000002074212,0.97186226,0.0016602502,0.000021790622,0.023860004],"study_design_scores_gemma":[0.0021336426,0.000047256657,0.07286463,0.000079015954,0.00006280927,0.000012408699,0.00033224514,0.00022739285,0.917789,0.0011751158,0.0051060733,0.000170409],"about_ca_topic_score_codex":0.000121748824,"about_ca_topic_score_gemma":0.000043990985,"teacher_disagreement_score":0.072685465,"about_ca_system_score_codex":0.000013021877,"about_ca_system_score_gemma":0.000038640992,"threshold_uncertainty_score":0.68515724},"labels":[],"label_agreement":null},{"id":"W4250833257","doi":"10.1007/s40278-015-5063-z","title":"Rivaroxaban-related liver injury: Canadian reports","year":2015,"lang":"en","type":"article","venue":"Reactions Weekly","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Rivaroxaban; Liver injury; Medicine; Pharmacology; Internal medicine","score_opus":0.1789416851004713,"score_gpt":0.4164638118746889,"score_spread":0.2375221267742176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4250833257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6395032,0.00069427706,0.00010895942,0.00890487,0.009851671,0.0013520729,0.00013253075,0.00074675836,0.3387057],"genre_scores_gemma":[0.9847362,0.000086596694,0.00010631543,0.0012956324,0.00028303123,0.00012247931,0.00004870655,0.000030956286,0.013290063],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981775,0.00037742377,0.00042164055,0.00035648173,0.00017063174,0.00049628527],"domain_scores_gemma":[0.99824387,0.00009070385,0.00018390115,0.00033220736,0.0002481494,0.00090114935],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0011224801,0.00022074494,0.00025952744,0.00034157303,0.0005135383,0.00003515543,0.00013091521,0.00064380903,0.0015429999],"category_scores_gemma":[0.00031416872,0.00022536241,0.00016062593,0.0004970187,0.00010898894,0.00029842506,0.000032693355,0.0012424511,0.0015645671],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00062827836,0.0022384827,0.024470452,0.00017189923,0.007798497,0.004216256,0.0070843315,0.003305591,0.087985225,0.024294803,0.7194488,0.1183574],"study_design_scores_gemma":[0.00031664767,0.00009230408,0.0011364615,0.000006526322,0.00044562056,0.0005851748,0.00013692808,0.0007926899,0.007567459,0.0022067588,0.98643273,0.00028067714],"about_ca_topic_score_codex":0.08863101,"about_ca_topic_score_gemma":0.026028235,"teacher_disagreement_score":0.34523305,"about_ca_system_score_codex":0.00054301653,"about_ca_system_score_gemma":0.00066755776,"threshold_uncertainty_score":0.99936974},"labels":[],"label_agreement":null},{"id":"W4253250098","doi":"10.1542/peds.2011-3035d","title":"Chronic Acetaminophen Exposure in Pediatric Acute Liver Failure","year":2013,"lang":"en","type":"article","venue":"PEDIATRICS","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Hospital for Sick Children; University of Arkansas for Medical Sciences; University of Pittsburgh; Johns Hopkins University; University of Cincinnati; University of Washington","keywords":"Medicine; Acetaminophen; Liver failure; Intensive care medicine; Internal medicine; Anesthesia","score_opus":0.05791655135927054,"score_gpt":0.34919866079567935,"score_spread":0.2912821094364088,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4253250098","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894432,0.0029941273,0.00014229302,0.0010979844,0.0016284992,0.0011621985,0.000037001268,0.000197806,0.0032969136],"genre_scores_gemma":[0.9883771,0.005078839,0.0003224841,0.00058559305,0.0036690184,0.0005060435,0.000029071323,0.000041857176,0.0013900026],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9976257,0.00040944948,0.00047617996,0.00046777003,0.00025379905,0.00076710776],"domain_scores_gemma":[0.9988284,0.00029552262,0.00019146978,0.0002750634,0.00012647877,0.00028305437],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00059115735,0.00032424272,0.00031589845,0.00043004635,0.00023861209,0.00005578355,0.0003910628,0.000855586,0.0027619605],"category_scores_gemma":[0.00009856882,0.00033084198,0.00012780887,0.0009945527,0.00006275443,0.00047495528,0.00014230459,0.0017712788,0.0033825317],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012145349,0.0008221868,0.8232308,0.0008051758,0.00015076471,0.00032098632,0.0030437787,0.0013950743,0.009387843,0.0007317465,0.052359838,0.10763033],"study_design_scores_gemma":[0.014488376,0.0016797034,0.60023934,0.00002853163,0.0021979313,0.00026091957,0.00045577003,0.013674252,0.020519247,0.0048003397,0.33760893,0.0040466688],"about_ca_topic_score_codex":0.00014929182,"about_ca_topic_score_gemma":0.00019126332,"teacher_disagreement_score":0.28524908,"about_ca_system_score_codex":0.00030115043,"about_ca_system_score_gemma":0.00021846776,"threshold_uncertainty_score":0.99991435},"labels":[],"label_agreement":null},{"id":"W4280559249","doi":"10.1136/bmj.o1197","title":"Acute hepatitis of unknown origin in children","year":2022,"lang":"en","type":"editorial","venue":"BMJ","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of Toronto; Toronto General Hospital; University of Saskatchewan","funders":"","keywords":"Acute hepatitis; Medicine; Hepatitis; Virology; Geology","score_opus":0.06301875381774497,"score_gpt":0.43837989291133067,"score_spread":0.3753611390935857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280559249","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.08528832,0.00030339623,0.000008390835,0.00037659853,0.90123576,0.0018426671,0.0021544572,0.00010105206,0.008689336],"genre_scores_gemma":[0.039630633,0.0035197728,0.00014892263,0.00039675456,0.943175,0.001300651,0.0027124884,0.00013699774,0.008978734],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99662566,0.0010764989,0.0007766986,0.00051569665,0.0005357174,0.00046974595],"domain_scores_gemma":[0.9982201,0.0006546382,0.00053962145,0.0003549565,0.000108678134,0.00012201897],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0016802156,0.00036608704,0.0006785293,0.0003770935,0.00019650326,0.000014362782,0.0005503216,0.0018295433,0.004245141],"category_scores_gemma":[0.00035989832,0.00041512508,0.00020886728,0.000478501,0.00012160774,0.00010198139,0.0002392033,0.004363086,0.00009548043],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032111863,0.00027939212,0.010970615,0.00009001105,0.0004793164,0.00006065857,0.00023268037,0.00014786569,0.0005535301,0.00015675162,0.9809371,0.005770909],"study_design_scores_gemma":[0.0016311449,0.00018982771,0.0010136415,0.00003899301,0.00023162088,0.000016376907,0.000007772799,0.00009976839,0.0028170173,0.00028242503,0.99325955,0.00041187447],"about_ca_topic_score_codex":0.0015327238,"about_ca_topic_score_gemma":0.00045734344,"teacher_disagreement_score":0.04565769,"about_ca_system_score_codex":0.0003640951,"about_ca_system_score_gemma":0.00062310265,"threshold_uncertainty_score":0.99983007},"labels":[],"label_agreement":null},{"id":"W4283326716","doi":"10.1111/bcp.15445","title":"Cloxacillin‐induced acute vanishing bile duct syndrome: A case study and literature review","year":2022,"lang":"en","type":"review","venue":"British Journal of Clinical Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Hamilton Health Sciences; HalTech; University of Saskatchewan","funders":"","keywords":"Cholestasis; Medicine; Cloxacillin; Gastroenterology; Internal medicine; Liver transplantation; Liver biopsy; Liver injury; Biopsy; Transplantation; Antibiotics; Penicillin; Biology","score_opus":0.38286142693374214,"score_gpt":0.5812692488881208,"score_spread":0.19840782195437867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283326716","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03230981,0.9460472,0.000003736613,0.00023926004,0.016819827,0.0039684256,0.00036810528,0.000071544026,0.00017211173],"genre_scores_gemma":[0.001778358,0.9907007,0.00007382473,0.003772556,0.0028627645,0.0003715642,0.00005477332,0.0001370202,0.0002484222],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9740904,0.017695533,0.0056966455,0.0010785918,0.00057976367,0.0008590523],"domain_scores_gemma":[0.98845714,0.005135193,0.004610703,0.00033659182,0.00041795845,0.0010424082],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.016004479,0.0008999722,0.006313683,0.0004890015,0.00102084,0.0001795541,0.0010853782,0.0018536763,0.0037405286],"category_scores_gemma":[0.0015037253,0.0009158895,0.0020143935,0.0011974518,0.0003096672,0.00054380565,0.0006643683,0.018966587,0.000043663305],"study_design_candidate":"case_report","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011216095,0.0015270502,0.000014655753,0.009441254,0.0031498363,0.32157847,0.00012414921,0.0000011739847,0.0000040584696,0.0000011603157,0.011423339,0.6526227],"study_design_scores_gemma":[0.0021918083,0.0014984054,0.0000043030786,0.007438798,0.009708849,0.41868213,0.00007928138,0.000007450327,0.0000015341085,0.000018830518,0.5599102,0.00045844915],"about_ca_topic_score_codex":0.000048622744,"about_ca_topic_score_gemma":0.000025426516,"teacher_disagreement_score":0.6521642,"about_ca_system_score_codex":0.00025111897,"about_ca_system_score_gemma":0.0011098561,"threshold_uncertainty_score":0.9994421},"labels":[],"label_agreement":null},{"id":"W4283654066","doi":"10.1016/j.xkme.2022.100515","title":"Acetaminophen Exacerbates Hypertension: A #NephJC Editorial on PATH-BP","year":2022,"lang":"en","type":"editorial","venue":"Kidney Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Department of Medicine, University of Toronto","keywords":"Acetaminophen; Medicine; Analgesic; Adverse effect; Journal club; Anesthesia; Internal medicine","score_opus":0.09544704490405426,"score_gpt":0.4007017991645763,"score_spread":0.30525475426052207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283654066","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009020845,0.00062126527,0.0000047209987,0.006072215,0.97688085,0.0013358694,0.0011688347,0.0004431737,0.012571015],"genre_scores_gemma":[0.001473979,0.001289778,0.0000274736,0.007369948,0.9740878,0.0005782747,0.0027573206,0.00018182654,0.012233647],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9919198,0.002361622,0.0010149148,0.0013530566,0.0022846663,0.0010659479],"domain_scores_gemma":[0.9923592,0.0043844017,0.0006623486,0.00086081866,0.00046944883,0.0012637513],"candidate_categories":["metaresearch","metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0043091592,0.0010272998,0.0014972553,0.00037780157,0.0016833612,0.000047479207,0.00095526513,0.0040947194,0.018527284],"category_scores_gemma":[0.011349767,0.000900541,0.00030487252,0.0005907772,0.0006107302,0.00013647322,0.00036672075,0.013328244,0.0009144139],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001657273,0.0004318039,0.000018019291,0.00035205728,0.0003840824,0.00029165123,0.000976416,0.000028617093,0.003887826,0.000047399237,0.98834836,0.003576493],"study_design_scores_gemma":[0.0064559407,0.0019035239,0.00000765489,0.00033121332,0.0006454508,0.000025414998,0.00016311313,0.00020337901,0.0009255513,0.00032528903,0.988171,0.0008424697],"about_ca_topic_score_codex":0.00043446443,"about_ca_topic_score_gemma":0.000011297268,"teacher_disagreement_score":0.01761287,"about_ca_system_score_codex":0.0007314273,"about_ca_system_score_gemma":0.001588168,"threshold_uncertainty_score":0.9998635},"labels":[],"label_agreement":null},{"id":"W4284665085","doi":"10.1093/jalm/jfac059","title":"On the Analytic Characteristics of Commercial Acetaminophen Assays in the United States","year":2022,"lang":"en","type":"review","venue":"The Journal of Applied Laboratory Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Acetaminophen; Analyte; Coefficient of variation; Food and drug administration; Overdiagnosis; Clearance; Medicine; Pharmacology; Accuracy and precision; Chemistry; Chromatography; Internal medicine; Statistics; Mathematics; Urology","score_opus":0.2255515533545394,"score_gpt":0.4439771496522977,"score_spread":0.21842559629775826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4284665085","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.069765136,0.90650755,0.000038467606,0.007525192,0.0044550467,0.004868997,0.00068306446,0.0000381984,0.0061183353],"genre_scores_gemma":[0.03165856,0.9618441,0.0000021103401,0.0054660873,0.00082229194,0.00006568929,0.00008290716,0.000038786617,0.000019486453],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9925217,0.0049268147,0.0014512119,0.00014631658,0.00064971944,0.0003042431],"domain_scores_gemma":[0.9882564,0.008740825,0.0023102367,0.00043938204,0.00016357996,0.00008958973],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.014773046,0.00039458842,0.0015069975,0.0004676607,0.0004071187,0.000010298304,0.0013575911,0.00035033876,0.0011736217],"category_scores_gemma":[0.00049376016,0.00017128924,0.00017165842,0.0018381056,0.00055888045,0.0000317192,0.00009059291,0.0057764207,0.000015654992],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003996746,0.0018698784,0.00004699762,0.008613418,0.0038996148,0.00030435133,0.03487871,0.00088590046,0.00044115595,0.020162804,0.052653164,0.8722473],"study_design_scores_gemma":[0.0007622542,0.0004212493,0.000044725235,0.00081018935,0.0023329817,0.000042893385,0.0017900686,0.00005355567,0.000043140706,0.0005511788,0.99298614,0.00016162028],"about_ca_topic_score_codex":0.00002578983,"about_ca_topic_score_gemma":0.000010125788,"teacher_disagreement_score":0.940333,"about_ca_system_score_codex":0.00021020992,"about_ca_system_score_gemma":0.00040465847,"threshold_uncertainty_score":0.99973947},"labels":[],"label_agreement":null},{"id":"W4286670717","doi":"10.3389/fphar.2022.934467","title":"Alanine Aminotransferase and Bilirubin Dynamic Evolution Pattern as a Novel Model for the Prediction of Acute Liver Failure in Drug-Induced Liver Injury","year":2022,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Outstanding Youth Science Fund Project of National Natural Science Foundation of China; Chinese Foundation for Hepatitis Prevention and Control; National Natural Science Foundation of China","keywords":"Bilirubin; Liver injury; Alanine aminotransferase; Liver failure; Drug; Medicine; Liver toxicity; Pharmacology; Internal medicine; Gastroenterology; Toxicity","score_opus":0.04654965339934039,"score_gpt":0.3443493815649064,"score_spread":0.297799728165566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286670717","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9387254,0.0004692584,0.052164506,0.0011901628,0.0034436358,0.0026868072,0.0012273076,0.000054907912,0.00003798258],"genre_scores_gemma":[0.99552923,0.00067679636,0.0005158303,0.0011909031,0.00010041977,0.0016459086,0.00007657555,0.000037182006,0.00022717193],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9974999,0.000683305,0.0005707932,0.0005250877,0.00019049118,0.00053043786],"domain_scores_gemma":[0.9991865,0.00028231277,0.0001934495,0.00016249357,0.00007113482,0.00010411733],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011991984,0.00028876404,0.00041853634,0.00052498205,0.0004113591,0.000008402959,0.0003409861,0.00034354784,0.00019092909],"category_scores_gemma":[0.000023412713,0.0002886519,0.00011523676,0.0004854045,0.00021431316,0.00020790272,0.0001648658,0.001616853,0.0000025676188],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006331024,0.0020260438,0.023188222,0.0003135068,0.0009039932,0.00008106159,0.010332767,0.0385329,0.85544974,0.00028805184,0.012505584,0.05004709],"study_design_scores_gemma":[0.0060170228,0.00040579302,0.0031183353,0.000011207499,0.0004526248,0.000057749363,0.00058609684,0.9623474,0.022331929,0.0005363835,0.0038699738,0.00026548852],"about_ca_topic_score_codex":0.00044339694,"about_ca_topic_score_gemma":0.00047152504,"teacher_disagreement_score":0.9238145,"about_ca_system_score_codex":0.00059600733,"about_ca_system_score_gemma":0.00019112289,"threshold_uncertainty_score":0.99995655},"labels":[],"label_agreement":null},{"id":"W4286716242","doi":"10.2337/dc22-0712","title":"Incretin-Based Drugs and the Risk of Acute Liver Injury Among Patients With Type 2 Diabetes","year":2022,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Janssen Pharmaceuticals; Canadian Institutes of Health Research; McGill University; Pfizer","keywords":"Medicine; Type 2 diabetes; Incretin; Diabetes mellitus; Internal medicine; Liver injury; Endocrinology","score_opus":0.014896531695026891,"score_gpt":0.28615946215135746,"score_spread":0.27126293045633054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286716242","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99682766,0.00034597344,7.0927547e-7,0.00008410002,0.0004403577,0.0007579642,0.00094223313,0.000047477937,0.0005535118],"genre_scores_gemma":[0.99856925,0.000041481013,0.000024631714,0.00088631915,0.000044586344,0.00020959252,0.00016430802,0.000023747722,0.00003611283],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9978262,0.0011759669,0.00019941134,0.00023846928,0.0002607893,0.00029912154],"domain_scores_gemma":[0.9987684,0.0004960256,0.00023564795,0.00019527272,0.00022255455,0.00008208191],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000693026,0.00017971241,0.00026529952,0.00009168098,0.00066086464,0.000015460111,0.00021000206,0.00013177007,0.00030566627],"category_scores_gemma":[0.00006961496,0.000131682,0.00007683148,0.00030916062,0.0004362917,0.00007360656,0.00015680636,0.00091444765,0.000012334627],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00056680717,0.00006752588,0.98691297,0.0000727519,0.00033229194,8.906078e-7,0.002411564,0.00023185136,0.0005472239,0.000029416096,0.00030498952,0.00852172],"study_design_scores_gemma":[0.009324627,0.0016306008,0.8492777,0.000044369965,0.0018448074,1.9598919e-7,0.0012669371,0.008095271,0.10863923,0.00025048773,0.018978719,0.0006470759],"about_ca_topic_score_codex":0.000041776282,"about_ca_topic_score_gemma":0.000007940697,"teacher_disagreement_score":0.13763529,"about_ca_system_score_codex":0.000059106835,"about_ca_system_score_gemma":0.000051027637,"threshold_uncertainty_score":0.5369836},"labels":[],"label_agreement":null},{"id":"W4292065811","doi":"10.21203/rs.3.rs-1919227/v1","title":"Molecular docking analysis and anti-apoptotic activity of Hypericum triquetrifolium Turra (St. John's-wort) in Cyclophosphamide-induced lung injury","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Hypericum; Cyclophosphamide; Apoptosis; Pharmacology; Traditional medicine; Docking (animal); Chemistry; Biology; Medicine; Biochemistry; Internal medicine; Veterinary medicine; Chemotherapy","score_opus":0.1184543667701241,"score_gpt":0.4840086945504737,"score_spread":0.3655543277803496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4292065811","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99271274,0.0013845215,0.00013911395,0.00046332055,0.000798581,0.0026343332,0.00043318796,0.00009904154,0.0013351454],"genre_scores_gemma":[0.9966451,0.00210327,0.000049774484,0.00008194807,0.00014741112,0.0006928711,0.00014502932,0.00006999165,0.00006463138],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9892987,0.0060897865,0.00087518437,0.0013254172,0.0012010974,0.0012098138],"domain_scores_gemma":[0.9966454,0.0011795769,0.0004905417,0.000850403,0.00043117427,0.0004029187],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0070272507,0.00057183433,0.0013798523,0.0033083134,0.00060510053,0.000099970974,0.00076841796,0.0015141814,0.00090695824],"category_scores_gemma":[0.0008473944,0.0006420144,0.00052213494,0.0047423886,0.00029355215,0.00019570443,0.0020849213,0.010372028,0.000007064448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025809538,0.002773566,0.40582785,0.0063840863,0.004613634,0.0010551313,0.0039420887,0.05326324,0.47663468,0.00048250728,0.00023998879,0.042202283],"study_design_scores_gemma":[0.0025525,0.00062160497,0.25521052,0.0004799784,0.0012750678,0.000018506602,0.0007925669,0.04712848,0.68526775,0.0014656254,0.0036111863,0.0015762451],"about_ca_topic_score_codex":0.003231561,"about_ca_topic_score_gemma":0.0002706011,"teacher_disagreement_score":0.20863305,"about_ca_system_score_codex":0.0010008673,"about_ca_system_score_gemma":0.00073622767,"threshold_uncertainty_score":0.9997821},"labels":[],"label_agreement":null},{"id":"W4292296491","doi":"10.1139/cjpp-2022-0127","title":"Nicotinamide adenine dinucleotide attenuates acetaminophen-induced acute liver injury via activation of PARP1, Sirt1, and Nrf2 in mice","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"NAD+ kinase; PARP1; Nicotinamide adenine dinucleotide; Nicotinamide; Chemistry; Superoxide dismutase; Glutathione peroxidase; Liver injury; Nicotinamide mononucleotide; Malondialdehyde; SOD2; Pharmacology; Biochemistry; Glutathione; Sirtuin 1; Poly ADP ribose polymerase; Molecular biology; Oxidative stress; Biology; Downregulation and upregulation; Enzyme; Polymerase","score_opus":0.049149541356912345,"score_gpt":0.3414088657428398,"score_spread":0.29225932438592744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4292296491","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957935,0.00061891193,0.000014619138,0.0014478052,0.0015572931,0.00038070747,0.00008589116,0.000008893036,0.00009237534],"genre_scores_gemma":[0.99706876,0.00040973406,0.00005721471,0.0020697983,0.0002546642,0.000038475016,0.000015271089,0.000021655207,0.00006439768],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970138,0.0014370569,0.0006358658,0.0003002062,0.00010005511,0.00051300094],"domain_scores_gemma":[0.99830014,0.0004631159,0.0005855545,0.00008484902,0.00013796559,0.0004283672],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010100887,0.00024950298,0.0005690597,0.0006068198,0.00046637046,0.000006891689,0.00028001468,0.00033056652,0.00186352],"category_scores_gemma":[0.0000536771,0.00026766196,0.00008875763,0.00034874064,0.0003944346,0.00023712325,0.00010282275,0.0019601781,0.000004536495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001061,0.00012928325,0.0071641444,0.0000974294,0.0003095557,0.00012326468,0.0014587347,0.00039309263,0.9821561,0.00015336434,0.00087189453,0.006082136],"study_design_scores_gemma":[0.0032606353,0.0014395862,0.024730574,0.000024572777,0.0003410142,0.00056241534,0.0003076707,0.0017810899,0.95780045,0.0020908054,0.0073059523,0.0003552413],"about_ca_topic_score_codex":0.001410648,"about_ca_topic_score_gemma":0.0007673086,"teacher_disagreement_score":0.02435566,"about_ca_system_score_codex":0.00021227353,"about_ca_system_score_gemma":0.00045613988,"threshold_uncertainty_score":0.9999775},"labels":[],"label_agreement":null},{"id":"W4292394995","doi":"10.1139/cjpp-2021-0628","title":"Effect of 4-hydroxychalcone as preventive and curative treatment in Wistar rats with liver injury","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Steatosis; Medicine; Gastroenterology; Carbon tetrachloride; Hepatotoxin; Internal medicine; Liver injury; Glutathione; Fibrosis; Malondialdehyde; Oxidative stress; Toxicity; Biology; Chemistry; Enzyme","score_opus":0.033107198936760916,"score_gpt":0.3684754063920079,"score_spread":0.335368207455247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4292394995","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99624187,0.0015794543,0.0000022724787,0.00040518434,0.00075489184,0.0006121822,0.00009074047,0.0000041739554,0.000309218],"genre_scores_gemma":[0.9985652,0.00045363745,0.000011609137,0.00062573253,0.00010994314,0.000089331326,0.000007531496,0.000013175739,0.00012384975],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963239,0.0026711468,0.0003521241,0.00023200492,0.0000642793,0.00035658563],"domain_scores_gemma":[0.99860704,0.0005573859,0.0003550452,0.000061601284,0.000070101276,0.0003488025],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00086246233,0.00022100842,0.000544456,0.0003980687,0.00035175015,0.0000038336407,0.00013188792,0.00018993417,0.0020181807],"category_scores_gemma":[0.000021748001,0.0001857292,0.0000661079,0.00021821733,0.00055724726,0.00012228853,0.000036535526,0.0010095836,0.0000032076166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009206535,0.00031523363,0.01249877,0.0002041291,0.0008979883,0.0008519135,0.007796716,0.0010923898,0.9481009,0.0004238779,0.0005276991,0.018083835],"study_design_scores_gemma":[0.006681773,0.020414129,0.003705769,0.000026011936,0.00045277696,0.0008373882,0.00039474684,0.00044320355,0.9400325,0.00111907,0.025585925,0.00030670897],"about_ca_topic_score_codex":0.0016833888,"about_ca_topic_score_gemma":0.0015827727,"teacher_disagreement_score":0.025058227,"about_ca_system_score_codex":0.00021720132,"about_ca_system_score_gemma":0.00062085723,"threshold_uncertainty_score":0.9988941},"labels":[],"label_agreement":null},{"id":"W4292488318","doi":"10.1007/s00330-022-09041-6","title":"Identification of MRI features associated with injury type, severity, and prognosis in drug-induced liver injury","year":2022,"lang":"en","type":"article","venue":"European Radiology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Natural Science Foundation of China","keywords":"Medicine; Liver injury; Internal medicine; Odds ratio; Ascites; Interventional radiology; Gastroenterology; Magnetic resonance imaging; Liver transplantation; Confidence interval; Culprit; Neuroradiology; Surgery; Radiology; Transplantation; Neurology","score_opus":0.05520864429480346,"score_gpt":0.3496054994614809,"score_spread":0.29439685516667746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4292488318","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960823,0.00019223569,0.0000052605433,0.0003535277,0.0006473215,0.0005820324,0.000097449156,0.00006908615,0.0019707584],"genre_scores_gemma":[0.9984574,0.0001445891,0.000019830306,0.0005782293,0.00007742994,0.00005997935,0.00004886445,0.000030925872,0.0005828022],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9950789,0.0037592791,0.00038145224,0.0003678179,0.00012339445,0.00028915846],"domain_scores_gemma":[0.99920505,0.00019315869,0.0003020821,0.00014954856,0.0000746697,0.00007551674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021067183,0.00017480055,0.00028273722,0.00024837276,0.00029160987,0.000010496769,0.00023226975,0.00013562017,0.00015705828],"category_scores_gemma":[0.00013761541,0.00017850801,0.000037323032,0.00050677796,0.00017175182,0.00009408855,0.00018768066,0.0011841614,0.000018211218],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0042307395,0.0018816411,0.20372017,0.0001686216,0.00064473675,0.0004396201,0.010360911,0.00070499454,0.70510256,0.0016027372,0.018526983,0.052616265],"study_design_scores_gemma":[0.0028234664,0.0020018846,0.8068569,0.000041028685,0.00021155308,0.00036681854,0.0005092498,0.0012273222,0.15736139,0.00037521814,0.027436133,0.0007890504],"about_ca_topic_score_codex":0.00008095624,"about_ca_topic_score_gemma":0.00009423397,"teacher_disagreement_score":0.6031367,"about_ca_system_score_codex":0.00011374308,"about_ca_system_score_gemma":0.000059949158,"threshold_uncertainty_score":0.72793454},"labels":[],"label_agreement":null},{"id":"W4298839826","doi":"10.17615/xt9g-6k72","title":"Hepatotoxicity Due to Hydroxycut: A Case Series","year":2020,"lang":"en","type":"article","venue":"UNC Libraries","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Series (stratigraphy); Computer science; Geology; Paleontology","score_opus":0.1585572950941015,"score_gpt":0.37498632921981473,"score_spread":0.21642903412571324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4298839826","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9549651,0.00019742986,0.0018951055,0.02341041,0.0012406986,0.0010837165,0.00018794354,0.0008388978,0.01618069],"genre_scores_gemma":[0.9704734,0.000008262652,0.0035331587,0.02400532,0.0008512325,0.00014371869,0.000021960768,0.000046517907,0.0009164345],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979675,0.00041680914,0.00038370967,0.0005034321,0.00017815384,0.00055038795],"domain_scores_gemma":[0.9986735,0.0001985946,0.000098741264,0.00023115987,0.00005907171,0.0007389364],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00030522427,0.00033059512,0.00039643655,0.00010855482,0.000705907,0.00014065085,0.00029851162,0.00044377908,0.0018022584],"category_scores_gemma":[0.000314315,0.0003326233,0.0001262978,0.0006297689,0.0002072619,0.0009404261,0.00025965017,0.000979687,0.0010809979],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006070336,0.0010866364,0.017986832,0.00096334436,0.0009891618,0.038391843,0.06855137,0.0021587566,0.18050814,0.50761926,0.10366212,0.07201219],"study_design_scores_gemma":[0.00092173537,0.0005074291,0.00012988625,0.000016050944,0.00007854391,0.0031374579,0.00072388403,0.0021392244,0.51143736,0.020750904,0.4595262,0.0006313446],"about_ca_topic_score_codex":0.0000722188,"about_ca_topic_score_gemma":0.00006480267,"teacher_disagreement_score":0.48686835,"about_ca_system_score_codex":0.000042913925,"about_ca_system_score_gemma":0.00014634295,"threshold_uncertainty_score":0.99991256},"labels":[],"label_agreement":null},{"id":"W4306173514","doi":"10.3389/fimmu.2022.1038067","title":"Corrigendum: Susceptibility to infections during acute liver injury depends on transient disruption of liver macrophage niche","year":2022,"lang":"en","type":"erratum","venue":"Frontiers in Immunology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Directorate for Biological Sciences; Universidade Federal de Minas Gerais","keywords":"Liver injury; Niche; Macrophage; Transient (computer programming); Immunology; Medicine; Biology; Cell biology; Internal medicine; Computer science; Genetics; Ecology","score_opus":0.05017001410891949,"score_gpt":0.35396873389250016,"score_spread":0.3037987197835807,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4306173514","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.77632815,0.0034134833,0.0010963116,0.00028602933,0.20543772,0.0029408536,0.0017151798,0.0002452324,0.0085370485],"genre_scores_gemma":[0.9103132,0.013773054,0.00038768884,0.000855672,0.0009925588,0.0012958806,0.0010089736,0.00019081913,0.071182184],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99443835,0.0022892999,0.0009784937,0.0010449109,0.00032259274,0.0009263353],"domain_scores_gemma":[0.9983624,0.00010986208,0.00048701346,0.0007325263,0.00012564586,0.00018255852],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0010427058,0.00065051037,0.0010711342,0.0014076969,0.0006435104,0.000017890698,0.0006997974,0.0024231775,0.0035191365],"category_scores_gemma":[0.00014152477,0.0007623348,0.00040640746,0.0009737638,0.00039863063,0.0001580462,0.00035612934,0.0075024795,0.00012595991],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013384871,0.0057235053,0.013350248,0.0011423508,0.0039187376,0.00097156456,0.010513398,0.0015106665,0.12202821,0.00030191866,0.7339945,0.09316004],"study_design_scores_gemma":[0.0028391478,0.0032134468,0.057753347,0.000155254,0.0007499371,0.00014331062,0.00048990553,0.0008422329,0.034536105,0.00023639534,0.89769596,0.0013449389],"about_ca_topic_score_codex":0.00063926296,"about_ca_topic_score_gemma":0.00077343755,"teacher_disagreement_score":0.20444517,"about_ca_system_score_codex":0.0016483027,"about_ca_system_score_gemma":0.00032076178,"threshold_uncertainty_score":0.99948275},"labels":[],"label_agreement":null},{"id":"W4306353440","doi":"10.56588/iabcd.v1i2.56","title":"A REVIEW ON HEPATOPROTECTIVE PLANTS AND COMPOUNDS","year":2022,"lang":"en","type":"review","venue":"International Association of Biologicals and Computational Digest","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Impact","funders":"","keywords":"Phytochemistry; Phytochemical; Detoxification (alternative medicine); Medicinal plants; Traditional medicine; Pharmacology; Medicine; Biology; Biotechnology; Alternative medicine","score_opus":0.21455652437131092,"score_gpt":0.46695719714115835,"score_spread":0.25240067276984746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4306353440","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007036209,0.98956877,0.000015242,0.00079462957,0.00077331817,0.0010514997,0.001228152,0.000048550075,0.0058162413],"genre_scores_gemma":[0.0032767954,0.99343187,0.000035277662,0.0016641512,0.00014959455,0.00030312993,0.0008534477,0.000013817525,0.00027192576],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974831,0.00092716457,0.00067428907,0.00041675987,0.0003181128,0.00018057432],"domain_scores_gemma":[0.9960781,0.0026111132,0.0010365966,0.00006677424,0.00012089259,0.000086560016],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011516255,0.00029237976,0.00089779776,0.00017433707,0.00025788764,0.000025680552,0.00021035297,0.00044600875,0.00057233474],"category_scores_gemma":[0.00043656517,0.00024250227,0.00020596915,0.00014742358,0.00008216266,0.00006052532,0.00015749189,0.0009355466,0.000030177529],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006753008,0.00038166557,0.00060463476,0.0036399974,0.0007082655,0.000008244412,0.00007603814,0.00006430388,0.000004972152,0.0038991722,0.002030409,0.9885148],"study_design_scores_gemma":[0.00031944364,0.0001970482,0.0005694623,0.0025493104,0.00012402073,0.0000363535,0.000010480846,0.00012875657,0.0000031846525,0.0022319753,0.9935913,0.00023865138],"about_ca_topic_score_codex":0.000018810002,"about_ca_topic_score_gemma":0.0000024383833,"teacher_disagreement_score":0.9915609,"about_ca_system_score_codex":0.00034305945,"about_ca_system_score_gemma":0.00008417725,"threshold_uncertainty_score":0.98889554},"labels":[],"label_agreement":null},{"id":"W4308053489","doi":"10.1007/s12072-022-10405-9","title":"Comparison of the prognostic models for mortality in idiosyncratic drug-induced liver injury","year":2022,"lang":"en","type":"article","venue":"Hepatology International","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Natural Science Foundation of China","keywords":"Medicine; Hepatology; Liver transplantation; Internal medicine; Potency; Liver injury; Liver disease; Gastroenterology; Surgery; Transplantation","score_opus":0.24576248053452482,"score_gpt":0.4780588737191039,"score_spread":0.23229639318457906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308053489","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913646,0.00007217947,0.00031713615,0.0012953423,0.0038257637,0.0011466668,0.0002114122,0.000034756158,0.0017321255],"genre_scores_gemma":[0.9978087,0.000010589654,0.000070265036,0.00088383764,0.00009019492,0.0009044247,0.000040733998,0.000015312948,0.00017593897],"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99768865,0.0008997424,0.00057096005,0.0002968114,0.0002632158,0.0002806371],"domain_scores_gemma":[0.99885297,0.00047332497,0.0003197751,0.00018861433,0.00011566277,0.00004963825],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009608991,0.00015661588,0.00031417733,0.00017282425,0.0003378693,0.000006973133,0.00056108955,0.00018242757,0.0005471717],"category_scores_gemma":[0.00017216397,0.00014865962,0.00014978983,0.00024031343,0.00012792375,0.000116021416,0.00025239537,0.0010039667,0.000008237626],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042433015,0.0010395431,0.95529073,0.00006278542,0.00019585241,0.000007917583,0.0020990644,0.0069538043,0.012963488,0.016820868,0.0014502616,0.0026913309],"study_design_scores_gemma":[0.002534868,0.00028992875,0.062312346,0.000025492896,0.00017259581,0.000062505474,0.0006233886,0.8078767,0.086739555,0.023387898,0.015553939,0.00042078225],"about_ca_topic_score_codex":0.00021172031,"about_ca_topic_score_gemma":0.0005374322,"teacher_disagreement_score":0.8929784,"about_ca_system_score_codex":0.00023450927,"about_ca_system_score_gemma":0.00018338532,"threshold_uncertainty_score":0.6062163},"labels":[],"label_agreement":null},{"id":"W4308730659","doi":"10.1186/s12879-022-07838-w","title":"Prevalence of hepatotoxicity among HIV-infected patients in Ethiopia: a systematic review and meta-analysis","year":2022,"lang":"en","type":"review","venue":"BMC Infectious Diseases","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Meta-analysis; Medicine; Publication bias; Subgroup analysis; Funnel plot; Cochrane Library; Medical microbiology; Internal medicine; Environmental health; Immunology","score_opus":0.17105367388840817,"score_gpt":0.4260032986866916,"score_spread":0.2549496247982834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308730659","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018922898,0.98605525,0.000020278667,0.0000042785073,0.00020062813,0.009089139,0.0023166016,0.00014827245,0.00027325566],"genre_scores_gemma":[0.010353826,0.9825801,0.000005140024,0.00023780204,0.000024686544,0.006221949,0.00028447577,0.000059773563,0.00023221236],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9875371,0.008568277,0.0020559048,0.00089882687,0.0004489334,0.0004909472],"domain_scores_gemma":[0.99448985,0.0022844002,0.002064809,0.0007049925,0.00016106621,0.00029488333],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0017302932,0.0008418364,0.007486732,0.0010128487,0.000318061,0.00003124158,0.00044282418,0.00070448586,0.003125509],"category_scores_gemma":[0.0017287725,0.00069996546,0.0030875457,0.0023697484,0.00023171614,0.0002105347,0.00031771045,0.0017478422,0.000032852266],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011770442,0.00093922636,0.05520633,0.90198183,0.04115337,0.00000925178,0.000059695463,0.000034741457,5.2540752e-8,0.000031083666,0.000037944912,0.00053471193],"study_design_scores_gemma":[0.00052304077,0.00012342773,0.0023972157,0.009566261,0.98110795,0.000012873773,0.0000051777247,0.00005879941,0.0000018441166,0.00004049922,0.0054401006,0.00072279084],"about_ca_topic_score_codex":0.00019860672,"about_ca_topic_score_gemma":0.0003016071,"teacher_disagreement_score":0.9399546,"about_ca_system_score_codex":0.00036769995,"about_ca_system_score_gemma":0.0003148596,"threshold_uncertainty_score":0.99954516},"labels":[],"label_agreement":null},{"id":"W4309941554","doi":"10.1038/s41467-022-34262-0","title":"Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Cancer Institute; Instituto de Salud Carlos III; Euskal Herriko Unibertsitatea; National Institutes of Health; Universidad de Navarra; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas; Banco Bilbao Vizcaya Argentaria; Ikerbasque, Basque Foundation for Science; Silence Therapeutics; Instituto de Investigación Marqués de Valdecilla; “la Caixa” Foundation; Ministerio de Economía y Competitividad; Spanish Clinical Research Network; Newcastle University; Cancer Research UK; Ministerio de Ciencia e Innovación; Ministerio de Ciencia, Innovación y Universidades; Fundación Científica Asociación Española Contra el Cáncer; Universidad de Málaga; York University; E-Rare; Agencia Estatal de Investigación; Universitat de València; McGill University","keywords":"Endoplasmic reticulum; Acetaminophen; Pharmacology; Cyclin D1; Chemistry; Magnesium; Cell biology; Cyclin; Liver injury; Medicine; Cancer research; Biochemistry; Biology; Cell cycle; Apoptosis","score_opus":0.16110273957889332,"score_gpt":0.4177137300851816,"score_spread":0.2566109905062883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309941554","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9416374,0.006851447,0.00015554855,0.0063709286,0.00322669,0.0024166624,0.00016921603,0.000545427,0.03862671],"genre_scores_gemma":[0.99122715,0.00062549894,0.0018352872,0.0032184531,0.00029614547,0.0011707672,0.00019716678,0.000053417218,0.0013760874],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9959621,0.0022726662,0.00042464276,0.0004635137,0.00036265075,0.0005144391],"domain_scores_gemma":[0.99697876,0.0004996949,0.00029776755,0.0019248053,0.00015208455,0.00014690215],"candidate_categories":["metaepi_narrow","sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0013607747,0.00030441312,0.0002967022,0.00015560244,0.0031156323,0.00004306365,0.001954566,0.00075100904,0.0004462462],"category_scores_gemma":[0.00025248644,0.0003545138,0.00015096995,0.0008215404,0.00017803421,0.00031483744,0.0012347335,0.008311934,0.00016403652],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025588187,0.0015176098,0.003002153,0.00016143642,0.0001698549,0.00008649094,0.0053971107,0.0011496522,0.95484614,0.014571771,0.0053809364,0.0134609435],"study_design_scores_gemma":[0.0014534465,0.00016260573,0.0025025215,0.000020295094,0.00010033625,0.000027248037,0.0005541987,0.008717172,0.1564881,0.00083195796,0.828507,0.00063509203],"about_ca_topic_score_codex":0.00008611718,"about_ca_topic_score_gemma":0.00014280963,"teacher_disagreement_score":0.8231261,"about_ca_system_score_codex":0.00042013745,"about_ca_system_score_gemma":0.00016856092,"threshold_uncertainty_score":0.9998907},"labels":[],"label_agreement":null},{"id":"W4318250355","doi":"10.3138/jammi-2022-0029","title":"Hepatotoxicity and tuberculosis treatment outcomes in chronic liver disease","year":2023,"lang":"en","type":"article","venue":"Journal of the Association of Medical Microbiology and Infectious Disease Canada","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; St. Michael's Hospital; West Park Healthcare Centre; University of Calgary","funders":"Centers for Disease Control and Prevention; International Union Against Tuberculosis and Lung Disease; World Health Organization","keywords":"Tuberculosis; Medicine; Disease; Chronic liver disease; Intensive care medicine; Internal medicine; Pathology; Cirrhosis","score_opus":0.028626050525225804,"score_gpt":0.3333269026124801,"score_spread":0.3047008520872543,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318250355","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9889062,0.00069473713,0.0000018174155,0.009035086,0.0009811146,0.00021754763,0.00012273258,0.000008943891,0.000031829113],"genre_scores_gemma":[0.995568,0.0029233373,6.3396584e-7,0.0012236041,0.00011131859,0.0000115973935,0.000006132457,0.0000058342466,0.00014955926],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9983385,0.00073801127,0.0003958239,0.00012512213,0.00017920557,0.0002232943],"domain_scores_gemma":[0.99847794,0.00064863963,0.0003806576,0.000074583324,0.000077987315,0.00034018428],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010431751,0.0001254695,0.0003087253,0.00010894999,0.00016835688,0.0000063899843,0.00012057207,0.00025263085,0.000098111355],"category_scores_gemma":[0.0010529667,0.000087270746,0.00010559871,0.00019303709,0.000112387155,0.00005999397,0.00006599266,0.0005204605,0.0000015997434],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012656715,0.00016825472,0.9905294,0.00007344016,0.00030776337,0.00006486259,0.00009994103,0.00015774302,0.0024476678,0.00012078554,0.002034973,0.0038685715],"study_design_scores_gemma":[0.0025753241,0.00014643303,0.97312945,0.00007242297,0.00025366232,0.000029391442,0.000024476085,0.000995025,0.001621474,0.0003863674,0.020633198,0.00013276623],"about_ca_topic_score_codex":0.017723478,"about_ca_topic_score_gemma":0.15814622,"teacher_disagreement_score":0.14042273,"about_ca_system_score_codex":0.0011588902,"about_ca_system_score_gemma":0.0014693326,"threshold_uncertainty_score":0.9888176},"labels":[],"label_agreement":null},{"id":"W4319456556","doi":"10.1159/000529169","title":"Non-Intentional N-Acetylcysteine Overdose Associated with Cerebral Edema and Brain Death","year":2023,"lang":"en","type":"article","venue":"Case Reports in Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Stollery Children's Hospital; University of Alberta; University of Saskatchewan; University of Calgary","funders":"","keywords":"Acetylcysteine; Dosing; Medicine; Anesthesia; acetaminophen overdose; Acetaminophen; Toxicity; Cerebral edema; Pharmacology; Internal medicine","score_opus":0.0682522367722544,"score_gpt":0.372299333796298,"score_spread":0.3040470970240436,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319456556","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960972,0.000020538788,0.00015822907,0.0014536337,0.00090846245,0.00055513735,0.00003545926,0.00015629626,0.00061502046],"genre_scores_gemma":[0.9971531,0.000016369058,0.000052607586,0.0015952376,0.00013096313,0.0001489453,0.00011257012,0.000030784722,0.00075940107],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99764663,0.00044449823,0.0005429054,0.0005391755,0.00014255723,0.0006842593],"domain_scores_gemma":[0.9989944,0.0002159178,0.00029764898,0.00020234077,0.00008211183,0.00020759794],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015475749,0.0002574779,0.00039232126,0.00031991056,0.00023111423,0.00001963835,0.000056401277,0.00040258456,0.000177419],"category_scores_gemma":[0.00025987293,0.00024722845,0.000072189934,0.00031463619,0.00021808941,0.00014058372,0.00012559678,0.0008413723,0.000018368017],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00074800494,0.0002683734,0.8973875,0.000047765207,0.00022241494,0.09422939,0.00037808923,0.0005883342,0.0036660766,0.00009724145,0.0015596867,0.00080709],"study_design_scores_gemma":[0.01143901,0.00277138,0.6844613,0.00019416655,0.00025042353,0.27166566,0.00054201594,0.016831107,0.0031454517,0.001387753,0.0066560456,0.00065568247],"about_ca_topic_score_codex":0.00011981776,"about_ca_topic_score_gemma":0.0011956511,"teacher_disagreement_score":0.21292622,"about_ca_system_score_codex":0.00014274518,"about_ca_system_score_gemma":0.000060098213,"threshold_uncertainty_score":0.999998},"labels":[],"label_agreement":null},{"id":"W4319990619","doi":"10.5863/1551-6776-28.1.20","title":"The Three W's of Acetaminophen In Children: Who, Why, and Which Administration Mode?","year":2023,"lang":"en","type":"article","venue":"The Journal of Pediatric Pharmacology and Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Acetaminophen; Medicine; Administration (probate law); Intensive care medicine; Pharmacology; Political science","score_opus":0.07993922012112314,"score_gpt":0.4031191892716914,"score_spread":0.32317996915056824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319990619","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908463,0.0037654904,0.00008446745,0.0038320085,0.0008910577,0.00041933308,0.000015826496,0.000016473401,0.00012905068],"genre_scores_gemma":[0.9590161,0.03951991,0.000012414947,0.0007307752,0.0006495699,0.00001033189,0.0000017901444,0.000013576158,0.000045545512],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99781483,0.0009855954,0.0005779713,0.00012302767,0.00017609113,0.0003224895],"domain_scores_gemma":[0.99776834,0.0013804175,0.0005016111,0.00010275999,0.00015427366,0.00009260059],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003262562,0.00017558693,0.00028101078,0.00020376284,0.00043922232,0.000016773356,0.0003121224,0.00029385107,0.000025662002],"category_scores_gemma":[0.000045275207,0.000112691305,0.000053199456,0.0006210612,0.00028527898,0.00014542094,0.000086405315,0.0012797371,0.0000044838403],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008303231,0.0009635598,0.7276043,0.0002362859,0.0025411788,0.00005489487,0.008744583,0.0037301746,0.119950004,0.0027213201,0.0056426628,0.11950775],"study_design_scores_gemma":[0.019083584,0.0038694933,0.7219315,0.00004417915,0.006733894,0.0016334343,0.001506835,0.04693565,0.119907714,0.045790203,0.031397674,0.0011658119],"about_ca_topic_score_codex":0.000014217786,"about_ca_topic_score_gemma":0.000082082785,"teacher_disagreement_score":0.11834194,"about_ca_system_score_codex":0.000027390337,"about_ca_system_score_gemma":0.00015181427,"threshold_uncertainty_score":0.5559892},"labels":[],"label_agreement":null},{"id":"W4320526216","doi":"10.1016/j.sciaf.2023.e01575","title":"Acute and sub-acute toxicological evaluation of ethanol extract of Alchornea cordifolia leaves in Wistar rats","year":2023,"lang":"en","type":"article","venue":"Scientific African","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Faculty of Veterinary Medicine, University of Calgary; Ahmadu Bello University","keywords":"Acute toxicity; Toxicity; Medicinal plants; Traditional medicine; Medicine; Pharmacology; Biology; Internal medicine","score_opus":0.23338779731263773,"score_gpt":0.45943739012690543,"score_spread":0.2260495928142677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4320526216","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949439,0.000121421595,0.000026728458,0.00032424237,0.0014377446,0.00082386396,0.0001747893,0.00005991827,0.0020873654],"genre_scores_gemma":[0.99908,0.00007937281,0.00006429433,0.000040685136,0.00003927816,0.000091061,0.00004087534,0.000011802265,0.0005526328],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972818,0.00089374935,0.0004832357,0.0004644434,0.00047484928,0.0004019429],"domain_scores_gemma":[0.9988718,0.00027003858,0.00026535924,0.00022822659,0.00022994372,0.00013465332],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0050505376,0.00016912645,0.00033904766,0.0004669591,0.0002186495,0.000027561198,0.0002241716,0.00031719066,0.0002643722],"category_scores_gemma":[0.00017541874,0.00016142598,0.0000822471,0.0015026359,0.0007404553,0.00016354313,0.00010850224,0.00049498415,0.0000456967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028370478,0.00022587148,0.0028844029,0.000038598242,0.00010540508,0.000016555698,0.0026549345,0.00029874264,0.96206933,0.00021770751,0.0006708985,0.03053383],"study_design_scores_gemma":[0.0012679932,0.00023232924,0.022541473,0.00002645914,0.00028432164,0.000011550885,0.00064580917,0.015733335,0.9539733,0.0023536508,0.0027119701,0.00021778754],"about_ca_topic_score_codex":0.000020060645,"about_ca_topic_score_gemma":0.00009556948,"teacher_disagreement_score":0.030316042,"about_ca_system_score_codex":0.00011572067,"about_ca_system_score_gemma":0.00026641038,"threshold_uncertainty_score":0.658276},"labels":[],"label_agreement":null},{"id":"W4321995520","doi":"10.14740/jmc4044","title":"Chronic Oral Amiodarone as a Cause of Acute Liver Failure","year":2023,"lang":"en","type":"article","venue":"Journal of Medical Cases","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Amiodarone; Etiology; Liver failure; Toxicity; Internal medicine; Atrial fibrillation","score_opus":0.16923652033870806,"score_gpt":0.4667020870440116,"score_spread":0.29746556670530355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321995520","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9881376,0.00074898027,0.000075557415,0.009068838,0.0015025536,0.000159174,0.0000373679,0.000041565756,0.00022834771],"genre_scores_gemma":[0.9947749,0.002791117,0.000049912003,0.0008368074,0.001157791,0.0000064722817,0.0000062197537,0.000015001038,0.00036178212],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99771833,0.00049394375,0.0005759737,0.00012447001,0.0007674053,0.00031986434],"domain_scores_gemma":[0.9982985,0.0006205738,0.00038044064,0.00010339192,0.0001662669,0.0004307884],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0020900313,0.0001445569,0.0003870928,0.0002448449,0.00013110027,0.000010993029,0.00031624638,0.000545279,0.0041446155],"category_scores_gemma":[0.0007663048,0.00011619331,0.0001957588,0.00041821066,0.00024191188,0.000159516,0.000092270006,0.00161424,0.0002538733],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003922422,0.0020334243,0.010680744,0.0012761009,0.006893581,0.10422179,0.00510296,0.0006372899,0.1429026,0.0030854102,0.3389828,0.38026088],"study_design_scores_gemma":[0.010512285,0.005653349,0.005827125,0.00064551074,0.0022651302,0.026790706,0.00092604157,0.0049214363,0.25427395,0.0016011002,0.6859025,0.0006808622],"about_ca_topic_score_codex":0.00008057874,"about_ca_topic_score_gemma":0.0001233528,"teacher_disagreement_score":0.37958002,"about_ca_system_score_codex":0.000111216345,"about_ca_system_score_gemma":0.00060980755,"threshold_uncertainty_score":0.99676573},"labels":[],"label_agreement":null},{"id":"W4323347771","doi":"10.1001/jama.2023.1080","title":"Association of FDA Mandate Limiting Acetaminophen (Paracetamol) in Prescription Combination Opioid Products and Subsequent Hospitalizations and Acute Liver Failure","year":2023,"lang":"en","type":"article","venue":"JAMA","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Medicine; Acetaminophen; Opioid; Odds ratio; Medical prescription; Toxicity; Anesthesia; Internal medicine; Emergency medicine; Pharmacology","score_opus":0.056093360966803146,"score_gpt":0.33961995358842934,"score_spread":0.28352659262162616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4323347771","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99465114,0.00015387805,0.000043225315,0.0035667159,0.0003848402,0.00076135696,0.00005401479,0.000084923304,0.00029988372],"genre_scores_gemma":[0.9972298,0.00129415,0.00011433249,0.00015058421,0.00009585928,0.00009073232,0.0001324254,0.000014194258,0.00087788334],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986725,0.0003707342,0.00029360532,0.0002682349,0.00015299415,0.00024194637],"domain_scores_gemma":[0.9992865,0.00015601005,0.00024012878,0.000092071816,0.00016641474,0.000058894915],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010896001,0.00013076433,0.00018876581,0.00022264449,0.0001873676,0.000045969882,0.00006691916,0.0003476369,0.000027469512],"category_scores_gemma":[0.00033164996,0.0001443722,0.000023708082,0.0004826155,0.000056420096,0.00046164377,0.00007401286,0.00042339586,0.000018872553],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031189164,0.0005154133,0.61603594,0.00095492287,0.0004632176,0.000047373127,0.013545392,0.00056477607,0.29843527,0.005450518,0.005183802,0.0584915],"study_design_scores_gemma":[0.0045292517,0.00023841401,0.7888176,0.00011245345,0.00029492922,0.000017855189,0.00052386185,0.028677182,0.16151577,0.0024789765,0.012407226,0.00038646345],"about_ca_topic_score_codex":0.00006896863,"about_ca_topic_score_gemma":0.00012685072,"teacher_disagreement_score":0.17278169,"about_ca_system_score_codex":0.00012610528,"about_ca_system_score_gemma":0.000033217195,"threshold_uncertainty_score":0.5887327},"labels":[],"label_agreement":null},{"id":"W4323351388","doi":"10.1093/jcag/gwac036.261","title":"A261 SEVERE ACUTE LIVER INJURY SECONDARY TO WILSON’S DISEASE: A CASE REPORT AND REVIEW OF THE LITERATURE","year":2023,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Jaundice; Liver injury; Viral hepatitis; Liver biopsy; Gastroenterology; Internal medicine; Liver disease; Abdominal pain; Cholestasis; Pathology; Biopsy","score_opus":0.029234951902658114,"score_gpt":0.34150352264772194,"score_spread":0.3122685707450638,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4323351388","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9532008,0.00046810842,0.0000019422032,0.04363331,0.0016523491,0.00040153693,0.00052565243,0.0000052423734,0.00011106494],"genre_scores_gemma":[0.9848157,0.0014608836,0.00001986691,0.012428689,0.00016113538,0.000009099391,0.000006628724,0.000010074108,0.0010878776],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.997812,0.0010574084,0.00055051246,0.000114824266,0.00019757032,0.00026773298],"domain_scores_gemma":[0.997889,0.00010680605,0.0011339723,0.0001760022,0.00038882863,0.0003054369],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002159444,0.00011296541,0.00032212405,0.00018932509,0.0002252476,0.000011271712,0.00023911719,0.00020696699,0.00009371043],"category_scores_gemma":[0.000705301,0.00008017633,0.00021125271,0.0003572549,0.00006442224,0.00009823419,0.0000794689,0.0009333526,0.0000034572886],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013300462,0.00013242588,0.6518958,0.0019852186,0.0018136115,0.011824428,0.002651668,0.00018161414,0.0024927459,0.00009444483,0.32122126,0.004376734],"study_design_scores_gemma":[0.0034978797,0.001231099,0.6937752,0.0045979773,0.0023034317,0.06447672,0.0001776641,0.00020689527,0.0019189063,0.0008119295,0.22664022,0.00036208073],"about_ca_topic_score_codex":0.0005347115,"about_ca_topic_score_gemma":0.029626707,"teacher_disagreement_score":0.09458104,"about_ca_system_score_codex":0.0004612584,"about_ca_system_score_gemma":0.00050451927,"threshold_uncertainty_score":0.9880801},"labels":[],"label_agreement":null},{"id":"W4323360343","doi":"10.7759/cureus.35852","title":"Use of Oral N-Acetylcysteine (NAC) in Non-Acetaminophen-Induced Acute Hepatic Failure","year":2023,"lang":"en","type":"article","venue":"Cureus","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Grand River Hospital","funders":"","keywords":"Medicine; Acetylcysteine; Acetaminophen; Liver failure; acetaminophen overdose; Gastroenterology; Internal medicine; Pharmacology; Antioxidant; Biochemistry","score_opus":0.21134816550155872,"score_gpt":0.42964453043676576,"score_spread":0.21829636493520704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4323360343","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995917,0.00004191487,0.000055338453,0.00076508545,0.0014471264,0.00086631405,0.0000795366,0.00019442764,0.00063323043],"genre_scores_gemma":[0.9976644,0.00019869833,0.00025473736,0.00040223775,0.00012414578,0.00015714797,0.00006502413,0.000041919866,0.0010916671],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99779433,0.00044691007,0.00054815505,0.0003976602,0.00021368168,0.00059926225],"domain_scores_gemma":[0.99888986,0.00026508296,0.00020632267,0.00036255672,0.00009600821,0.00018017835],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007751986,0.00029495117,0.0005024619,0.0002758555,0.00015701861,0.000024291025,0.00029799077,0.0006328143,0.0004013614],"category_scores_gemma":[0.00015781619,0.00030134938,0.00013882807,0.0010626549,0.000103983984,0.00037382985,0.0001474587,0.0009628367,0.000449786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003389591,0.00035076292,0.01676635,0.00018634895,0.00037047526,0.00019712269,0.002724603,0.0009390361,0.962549,0.00034945834,0.0035616094,0.011666281],"study_design_scores_gemma":[0.0057726232,0.0009885529,0.02916395,0.0001532693,0.00042166372,0.00006816098,0.00068580045,0.03494113,0.844031,0.0008196421,0.08187724,0.001076967],"about_ca_topic_score_codex":0.0006443938,"about_ca_topic_score_gemma":0.0012164029,"teacher_disagreement_score":0.11851799,"about_ca_system_score_codex":0.00015331451,"about_ca_system_score_gemma":0.000096940224,"threshold_uncertainty_score":0.99994385},"labels":[],"label_agreement":null},{"id":"W4327918566","doi":"10.47070/ayushdhara.v10i1.1162","title":"Efficacy of Virechana in Treating Raised Uric Acid Level in Gouty Arthritis - A Cohort Study","year":2023,"lang":"en","type":"article","venue":"AYUSHDHARA","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Gout; Hyperuricemia; Gouty arthritis; Internal medicine; Uric acid; Cohort; Arthritis; Surgery; Gastroenterology; Physical therapy","score_opus":0.21643842413520467,"score_gpt":0.4495466148428066,"score_spread":0.23310819070760194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4327918566","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946621,0.0001197253,0.0000193125,0.00014937572,0.0005234397,0.0019064462,0.00004815246,0.00013736248,0.0024340542],"genre_scores_gemma":[0.9988367,0.00019303092,0.000031659663,0.00015685803,0.00009184734,0.00037826024,0.000028867413,0.000026891306,0.00025589686],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99732715,0.0008917306,0.0006441406,0.00043179528,0.00020715561,0.00049801526],"domain_scores_gemma":[0.99896336,0.0004924561,0.00016953847,0.0002316038,0.000040608862,0.00010243041],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002222279,0.0002255168,0.00050331483,0.00057700335,0.00013615943,0.000012444275,0.00021821307,0.00033443066,0.0003797507],"category_scores_gemma":[0.00032812348,0.00024903752,0.000091704096,0.001578801,0.000071773924,0.00014445087,0.000091817354,0.0009249466,0.0002410745],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005856003,0.0024240692,0.8013762,0.00005917205,0.00014176442,0.0002674646,0.006663957,0.00070085,0.06918883,0.00009316408,0.00020745382,0.11829145],"study_design_scores_gemma":[0.008080832,0.00036813968,0.91919565,0.00008435216,0.00003954262,0.000008536052,0.00085810554,0.0022483338,0.06759524,0.00022804436,0.0009813242,0.0003118889],"about_ca_topic_score_codex":0.0006833399,"about_ca_topic_score_gemma":0.001244213,"teacher_disagreement_score":0.117979564,"about_ca_system_score_codex":0.0001315011,"about_ca_system_score_gemma":0.000082637554,"threshold_uncertainty_score":0.9999962},"labels":[],"label_agreement":null},{"id":"W4360993486","doi":"10.1097/hc9.0000000000000102","title":"Hepatic C-X-C chemokine receptor type 6–expressing innate lymphocytes limit detrimental myeloid hyperactivation in acute liver injury","year":2023,"lang":"en","type":"article","venue":"Hepatology Communications","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Novo Nordisk; Berlin Institute of Health; Bundesministerium für Bildung und Forschung; CSL Behring; Gilead Sciences; Alnylam Pharmaceuticals; Pfizer; Allergan; Deutsche Forschungsgemeinschaft; Bristol-Myers Squibb","keywords":"Liver injury; Chemokine; Immunology; Inflammation; Innate immune system; Myeloid; Biology; Natural killer T cell; Chemokine receptor; Immunophenotyping; CD8; Cancer research; Flow cytometry; Immune system; Endocrinology","score_opus":0.17731003102698847,"score_gpt":0.44003498452370055,"score_spread":0.2627249534967121,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4360993486","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909712,0.0005470204,0.000029671648,0.003604963,0.0010020247,0.00067289645,0.000059237816,0.00039926628,0.0027137238],"genre_scores_gemma":[0.9895204,0.006725024,0.0010224524,0.0013883818,0.00007633732,0.000304613,0.0004854489,0.000042823176,0.00043454397],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971206,0.0012550164,0.00057321665,0.00037921706,0.00014410277,0.00052783295],"domain_scores_gemma":[0.99762017,0.0009813419,0.00025348493,0.0008571875,0.00015574465,0.00013204955],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00086203206,0.00026922792,0.0003719016,0.00060425454,0.00075460284,0.000031021416,0.00074748474,0.00063126936,0.00038694532],"category_scores_gemma":[0.00032946377,0.00030650315,0.00008548264,0.001703535,0.0003414256,0.00038149298,0.0005131891,0.001339414,0.0013671254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00084307184,0.0010755769,0.17945535,0.00008406458,0.00039493787,0.00006157146,0.0032826005,0.00012876106,0.7393181,0.0021081618,0.0052115456,0.06803626],"study_design_scores_gemma":[0.0040037674,0.00041840674,0.02827923,0.00014715036,0.00030496967,0.00019845489,0.0005568648,0.10603445,0.59133863,0.0019439152,0.26559564,0.0011784798],"about_ca_topic_score_codex":0.0003836442,"about_ca_topic_score_gemma":0.00025076384,"teacher_disagreement_score":0.2603841,"about_ca_system_score_codex":0.00046244715,"about_ca_system_score_gemma":0.00026023336,"threshold_uncertainty_score":0.9999387},"labels":[],"label_agreement":null},{"id":"W4362601094","doi":"10.14670/hh-18-614","title":"Histopathological characteristics of liver biopsy performed at different time points in drug-induced liver injury.","year":2024,"lang":"en","type":"article","venue":"PubMed","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Liver injury; Liver biopsy; Biopsy; Cholestasis; Internal medicine; Gastroenterology; Pathological; Necrosis; Bilirubin; Alkaline phosphatase; Pathology; Biology","score_opus":0.09699674680447394,"score_gpt":0.3394752337006072,"score_spread":0.24247848689613327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362601094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99235135,0.00025033628,0.000007529884,0.00034567903,0.0023701945,0.0012509387,0.00010688994,0.00016647941,0.003150576],"genre_scores_gemma":[0.99439716,0.00025393814,0.000018317387,0.00031801852,0.00030263973,0.00093621557,0.000040886123,0.00003332627,0.0036995115],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99740857,0.0006391354,0.0005775413,0.00049784535,0.00022250279,0.00065443455],"domain_scores_gemma":[0.99900836,0.00033147912,0.00014397578,0.00021860568,0.00005638964,0.00024118951],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011179685,0.000313631,0.00047434392,0.00033550287,0.00014371877,0.00002980656,0.00025340967,0.0005502756,0.00097114017],"category_scores_gemma":[0.0001660456,0.0002749237,0.00017044571,0.00033454355,0.00017486935,0.00015769538,0.00026925586,0.0011558342,0.0005330974],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013345826,0.0011410468,0.023001725,0.0006522008,0.00014398004,0.00079440005,0.0026538072,0.0000031245931,0.13359055,0.0005818881,0.0014978466,0.83460486],"study_design_scores_gemma":[0.0010935887,0.0001304316,0.7880428,0.00007142674,0.00016994236,0.00017186756,0.000020189022,0.004258026,0.171757,0.0003269137,0.03333105,0.00062675617],"about_ca_topic_score_codex":0.00005440652,"about_ca_topic_score_gemma":0.000026438778,"teacher_disagreement_score":0.8339781,"about_ca_system_score_codex":0.00055152824,"about_ca_system_score_gemma":0.000035519177,"threshold_uncertainty_score":0.9999703},"labels":[],"label_agreement":null},{"id":"W4364374893","doi":"10.3389/fphar.2023.1193099","title":"Editorial: Advances in drug-induced diseases","year":2023,"lang":"en","type":"editorial","venue":"Frontiers in Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Impact","funders":"Chongqing Science and Technology Commission","keywords":"Medicine; Drug; Pharmacology","score_opus":0.038292516038576384,"score_gpt":0.4158379258438581,"score_spread":0.37754540980528173,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4364374893","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002390812,0.0046988702,0.000028223069,0.0003629615,0.9875728,0.0018731528,0.0008742656,0.00052171847,0.0016772004],"genre_scores_gemma":[0.0027689727,0.020066408,0.000082437655,0.00035311226,0.9723913,0.0018288386,0.00069821754,0.000234846,0.0015758426],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9912725,0.002910681,0.0014305651,0.0016004596,0.0008715055,0.0019142719],"domain_scores_gemma":[0.9947317,0.0034204843,0.0006591097,0.00041441977,0.00026510816,0.0005091465],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0024891158,0.001041851,0.0017705219,0.0019215466,0.0003168852,0.000051545878,0.0013150218,0.0047872397,0.00036690457],"category_scores_gemma":[0.0014765289,0.0012066319,0.00028356205,0.0017012954,0.00038286377,0.0006213084,0.00037249184,0.009587574,0.00045821286],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015385597,0.00063793885,0.0015060134,0.00047597603,0.00020819457,0.00034166253,0.00043290344,0.0005856432,0.0013423642,0.000013856216,0.97763664,0.015280248],"study_design_scores_gemma":[0.005569534,0.00017054816,0.00006265511,0.00012069615,0.0003063487,0.0000014712122,0.00017333581,0.0005591847,0.001904763,0.0018386265,0.988199,0.0010938549],"about_ca_topic_score_codex":0.00037681448,"about_ca_topic_score_gemma":0.0008989719,"teacher_disagreement_score":0.015367538,"about_ca_system_score_codex":0.0015574506,"about_ca_system_score_gemma":0.001094991,"threshold_uncertainty_score":0.99903834},"labels":[],"label_agreement":null},{"id":"W4366336896","doi":"10.1101/2023.04.17.537197","title":"Growth Hormone Accelerates Recovery From Acetaminophen-Induced Murine Liver Injury","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Acetaminophen; Liver injury; Medicine; Messenger RNA; Toxicity; Testosterone (patch); Hormone; Programmed cell death; Pharmacology; Endocrinology; Internal medicine; Biology; Apoptosis; Gene; Biochemistry","score_opus":0.10902884709383727,"score_gpt":0.33368899060250773,"score_spread":0.22466014350867047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366336896","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9829069,0.0013129523,0.00026167842,0.00064211525,0.009446994,0.0018873184,0.0016847203,0.0017985038,0.000058859794],"genre_scores_gemma":[0.9891647,0.0045018136,0.0009037827,0.0011916433,0.002900746,0.0009033018,0.00000895812,0.00034708428,0.00007798802],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9939629,0.0011312674,0.0011138035,0.001960494,0.0005480708,0.0012834786],"domain_scores_gemma":[0.9958523,0.00055935915,0.00085580995,0.0013510707,0.00067977404,0.0007016664],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0016695391,0.0012370631,0.0012036349,0.00066477817,0.00068901345,0.0003135416,0.0012359215,0.0032869074,0.0005571113],"category_scores_gemma":[0.0005889296,0.0014220712,0.00042928135,0.0009732788,0.00021495097,0.00048212576,0.0013462352,0.005381745,0.0022401824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054192886,0.00045876054,0.003033731,0.00033644267,0.0010173869,0.00027424836,0.000051199335,0.000074142765,0.9903566,0.00017814348,0.0036095337,0.00006783907],"study_design_scores_gemma":[0.0013132602,0.00022337375,0.06899979,0.00021408759,0.0005207479,5.1275443e-8,0.000006291449,0.0010961093,0.9171635,0.000089482346,0.008736917,0.0016363811],"about_ca_topic_score_codex":0.0011320144,"about_ca_topic_score_gemma":0.0000262993,"teacher_disagreement_score":0.07319313,"about_ca_system_score_codex":0.0006984338,"about_ca_system_score_gemma":0.00072217605,"threshold_uncertainty_score":0.99882287},"labels":[],"label_agreement":null},{"id":"W4366495356","doi":"10.15562/phytomedicine.2022.198","title":"Plants secondary metabolites and antiviral properties","year":2023,"lang":"en","type":"article","venue":"Discovery Phytomedicine - Journal of Natural Products Research and Ethnopharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Pandemic; Coronavirus disease 2019 (COVID-19); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Virology; 2019-20 coronavirus outbreak; Adjuvant; SAFER; Viral replication; Biology; Virus; Medicine; Pharmacology; Immunology; Infectious disease (medical specialty); Disease; Internal medicine","score_opus":0.24265287383839232,"score_gpt":0.4780681497719114,"score_spread":0.2354152759335191,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366495356","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9607265,0.02315632,0.0000013879179,0.011749974,0.0032893582,0.0005698027,0.000038851096,0.000049095455,0.00041869897],"genre_scores_gemma":[0.97830474,0.016782695,0.000024253575,0.00076900417,0.0019482457,0.000022646134,0.000016664657,0.000026478712,0.0021052572],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996286,0.0012192564,0.0006081756,0.00043619936,0.0005600295,0.000890385],"domain_scores_gemma":[0.9979395,0.0007525719,0.0002529736,0.00013665982,0.00062639965,0.00029187475],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0050601833,0.00027978094,0.00062062684,0.0010783285,0.00058683916,0.00007531135,0.00031305538,0.00028730868,0.000054014472],"category_scores_gemma":[0.00091311074,0.00020010798,0.00006365047,0.001027018,0.0013946994,0.0010742893,0.0002869687,0.0042417576,0.00003355694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024563686,0.00017566652,0.001512983,0.00044747346,0.00035895518,0.00043816192,0.0014209191,0.0000064786836,0.92665166,0.00009347999,0.015331163,0.05110669],"study_design_scores_gemma":[0.0052978992,0.0017289106,0.015045501,0.00016170621,0.0001361077,0.00067954336,0.0017863913,0.00050893374,0.8784503,0.0027575276,0.09307063,0.00037656957],"about_ca_topic_score_codex":0.000025122432,"about_ca_topic_score_gemma":0.000005520096,"teacher_disagreement_score":0.07773947,"about_ca_system_score_codex":0.00006212846,"about_ca_system_score_gemma":0.00034754453,"threshold_uncertainty_score":0.9980555},"labels":[],"label_agreement":null},{"id":"W4376131204","doi":"10.1016/j.jhep.2023.04.033","title":"Nomenclature, diagnosis and management of drug-induced autoimmune-like hepatitis (DI-ALH): An expert opinion meeting report","year":2023,"lang":"en","type":"review","venue":"Journal of Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":150,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"NIHR Nottingham Biomedical Research Centre; Universitätsklinikum Hamburg-Eppendorf; Instituto de Salud Carlos III; Medical School, University of Michigan; National Institutes of Health; Renji Hospital; Spanish Clinical Research Network; Assistance publique-Hôpitaux de Paris; Universitätsspital Zürich; Universidade do Porto; European Regional Development Fund; Universität Zürich; National Cancer Institute; Háskóli Íslands; Landspítali Háskólasjúkrahús; Newcastle upon Tyne Hospitals NHS Foundation Trust; Humanitas Research Hospital; Medizinischen Hochschule Hannover; University of Toronto; Shanghai Jiao Tong University; Vrije Universiteit Amsterdam; Humanitas University; Università degli Studi di Milano-Bicocca; University of Bern; University of Nottingham; European Cooperation in Science and Technology; Johns Hopkins University; Università degli Studi di Padova; Nottingham University Hospitals NHS Trust; Università degli Studi di Palermo; National Institute for Health and Care Research; King's College London; Amsterdam University Medical Centers; Indiana University Health; Sheffield Teaching Hospitals NHS Foundation Trust; Inselspital, Universitätsspital Bern; Eli Lilly and Company; Birmingham Biomedical Research Centre; Universidad de Málaga; Universidad Nacional de Rosario; Institut National de la Santé et de la Recherche Médicale; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas; Sir Jules Thorn Charitable Trust","keywords":"Autoimmune hepatitis; Medicine; Immunosuppression; Hepatitis; Liver injury; Drug; Immunology; Internal medicine; Pharmacology","score_opus":0.26233849462929676,"score_gpt":0.49128887446930297,"score_spread":0.2289503798400062,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376131204","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.023167955,0.9642838,0.000027062737,0.00025458107,0.010074074,0.0013721662,0.00004781852,0.00008883605,0.0006836565],"genre_scores_gemma":[0.0030918738,0.9949694,0.0005348712,0.00018556311,0.00061397214,0.00026989807,0.00007008054,0.00010989421,0.00015444637],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99315673,0.002226384,0.0029240923,0.0006251171,0.00041843313,0.0006492196],"domain_scores_gemma":[0.994186,0.0008380002,0.0038613686,0.0004874804,0.00029302412,0.0003341718],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0034410583,0.0006834667,0.003008486,0.00091914146,0.0003365115,0.000034904657,0.000653882,0.001554566,0.000109096865],"category_scores_gemma":[0.00015417539,0.0006160769,0.0007021267,0.00065729243,0.00020823814,0.00030316674,0.00033123672,0.002491261,0.00002746026],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014572318,0.0006415366,0.004523497,0.016218081,0.0032222492,0.003410246,0.0008627432,0.000008213453,0.00013619242,0.00035513958,0.002833719,0.96764266],"study_design_scores_gemma":[0.00088198006,0.00041038403,0.00025059617,0.0066159014,0.0011389368,0.004749338,0.00010257199,0.00006443329,0.0004158733,0.00027885637,0.9845177,0.0005734089],"about_ca_topic_score_codex":0.000313174,"about_ca_topic_score_gemma":0.00009805251,"teacher_disagreement_score":0.981684,"about_ca_system_score_codex":0.00030361506,"about_ca_system_score_gemma":0.00037161203,"threshold_uncertainty_score":0.99981004},"labels":[],"label_agreement":null},{"id":"W4376616796","doi":"10.1097/hep.0000000000000458","title":"Future directions in acute liver failure","year":2023,"lang":"en","type":"review","venue":"Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":123,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Cancer Institute; Vagelos College of Physicians and Surgeons, Columbia University; Imperial College London; University of Alberta; Institut National de la Santé et de la Recherche Médicale; University of Texas Southwestern Medical Center; University of South Carolina; Virginia Commonwealth University; Medical School, University of Michigan; Université de Montréal; Northwestern University; Medical University of South Carolina; Southwestern Medical Foundation; University of Pennsylvania; University of Pittsburgh; National Institute of Diabetes and Digestive and Kidney Diseases; Johns Hopkins University; University of Southern California","keywords":"Medicine; Hepatic encephalopathy; Cirrhosis; Liver disease; Liver injury; Liver failure; Gastroenterology; Internal medicine; Natural history; Encephalopathy; Intensive care medicine","score_opus":0.22744888405329658,"score_gpt":0.47553296142121126,"score_spread":0.24808407736791468,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376616796","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00021024971,0.9871381,0.000008737738,0.0005414326,0.007549082,0.0017132314,0.00029652854,0.0005322737,0.0020103753],"genre_scores_gemma":[0.00007052997,0.9942063,0.00006273309,0.00045465125,0.0012484152,0.0012162611,0.0002683087,0.00012535055,0.0023474437],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99497896,0.0021949804,0.0009297011,0.00084746425,0.00014645747,0.00090244255],"domain_scores_gemma":[0.99819356,0.00067648455,0.00040328767,0.00042920542,0.00006427881,0.00023319799],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0007720789,0.0006875496,0.0021067827,0.0009703033,0.00035647047,0.000024327841,0.00051278545,0.0039626053,0.0010966433],"category_scores_gemma":[0.000083220344,0.0006531145,0.00060530973,0.0015436163,0.0001899808,0.00011983242,0.00021033047,0.0047236574,0.0052396073],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030884476,0.00018185882,0.00019619206,0.005043659,0.000750807,0.0011487475,0.00032473472,0.0000010075837,0.0000033579813,0.001440037,0.009297227,0.9815815],"study_design_scores_gemma":[0.00038936955,0.00005236106,0.00001041086,0.00067661016,0.0011242717,0.0007981995,0.000030245557,0.00014969021,0.000010731985,0.0002607205,0.995927,0.00057038467],"about_ca_topic_score_codex":0.00016685954,"about_ca_topic_score_gemma":0.0029010153,"teacher_disagreement_score":0.9866298,"about_ca_system_score_codex":0.00039929475,"about_ca_system_score_gemma":0.00045800064,"threshold_uncertainty_score":0.9998165},"labels":[],"label_agreement":null},{"id":"W4379276081","doi":"10.33380/2305-2066-2023-12-2-146-153","title":"Phase I Pharmacokinetics Study of Drug for Infusion «Areplivir» (INN: Favipiravir) (LLC \"PROMOMED RUS\", Russia)","year":2023,"lang":"en","type":"article","venue":"Drug development & registration","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Public Health Association","funders":"","keywords":"Pharmacokinetics; Pharmacology; Drug; Medicine; Favipiravir; Coronavirus disease 2019 (COVID-19); Internal medicine; Disease","score_opus":0.1664712180694004,"score_gpt":0.44900681623139765,"score_spread":0.28253559816199725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379276081","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99106133,0.00005107683,0.00060102355,0.0011904936,0.0017468715,0.0037469133,0.000068958805,0.00036982857,0.0011635158],"genre_scores_gemma":[0.9936178,0.00012243501,0.00053133204,0.0004641642,0.00022520352,0.0010690541,0.000563105,0.000052154417,0.0033547883],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966987,0.00046524612,0.001096107,0.0006510561,0.00051985035,0.00056906533],"domain_scores_gemma":[0.9983316,0.00026460143,0.0006107707,0.0003385552,0.0002505667,0.00020391397],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0026412138,0.00039460332,0.00044180927,0.00043687076,0.000721536,0.000052153984,0.0003538601,0.000250034,0.00017910053],"category_scores_gemma":[0.00013176432,0.0004143557,0.00011649429,0.0009131405,0.000102903694,0.0002841548,0.00011270923,0.0006237597,0.00013098789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026720625,0.010898043,0.0058629946,0.0007411478,0.00056551176,0.00006437825,0.047004383,0.0014593119,0.5865972,0.0004917363,0.052025974,0.29161724],"study_design_scores_gemma":[0.015747,0.0007581603,0.0045766756,0.00008260416,0.00025054585,0.000009855941,0.0033443004,0.009417614,0.57812536,0.00039106756,0.38647202,0.00082477153],"about_ca_topic_score_codex":0.000053545526,"about_ca_topic_score_gemma":0.00018242723,"teacher_disagreement_score":0.33444607,"about_ca_system_score_codex":0.00017688755,"about_ca_system_score_gemma":0.00029915734,"threshold_uncertainty_score":0.99983084},"labels":[],"label_agreement":null},{"id":"W4379522682","doi":"10.1136/annrheumdis-2023-eular.2761","title":"POS0023 PERFORMANCE OF BASDAI VS. ASDAS IN EVALUATING AXIAL INVOLVEMENT IN PATIENTS WITH PSA TREATED WITH GUSELKUMAB: POOLED ANALYSIS OF TWO PHASE 3 STUDIES","year":2023,"lang":"en","type":"article","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Toronto Western Hospital","funders":"","keywords":"Medicine; BASDAI; Internal medicine; Arthritis; Psoriatic arthritis","score_opus":0.168737350630239,"score_gpt":0.46556270413966094,"score_spread":0.29682535350942196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379522682","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984363,0.00003197715,0.000007483577,0.000057058398,0.000086915636,0.0009697137,0.000045964334,0.000054952736,0.00030968298],"genre_scores_gemma":[0.99923533,0.00007766534,0.00012411822,0.00012449399,0.000016646769,0.00014276116,0.000112999995,0.000017430864,0.00014853972],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99765384,0.00055237557,0.00068905635,0.00034873662,0.00037331163,0.0003826808],"domain_scores_gemma":[0.99883014,0.0002649086,0.00033964985,0.00019460471,0.0003016924,0.000069025366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016359641,0.00024244143,0.0006924011,0.0014360454,0.000107276355,0.000005751508,0.00014857878,0.00014509157,0.00023429912],"category_scores_gemma":[0.00006585701,0.00018574698,0.00007255582,0.0043112906,0.00015238326,0.00018414439,0.00006591024,0.0004318562,0.000009268721],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0053120125,0.001374276,0.9427764,0.00016255316,0.0026002505,0.000007422281,0.0032563144,0.030030299,0.0060801404,0.000033869997,0.000019119818,0.008347368],"study_design_scores_gemma":[0.033619255,0.006107539,0.60455936,0.00022672443,0.0030648673,4.908744e-7,0.00144093,0.19943893,0.15097138,0.00003229631,0.00004567457,0.0004925299],"about_ca_topic_score_codex":0.00045151962,"about_ca_topic_score_gemma":0.0025160427,"teacher_disagreement_score":0.338217,"about_ca_system_score_codex":0.00016755518,"about_ca_system_score_gemma":0.000089260044,"threshold_uncertainty_score":0.75745416},"labels":[],"label_agreement":null},{"id":"W4380568963","doi":"10.46747/cfp.6906403","title":"When beauty is more than skin deep","year":2023,"lang":"en","type":"article","venue":"Canadian Family Physician","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; Maple Leaf Medical Clinic; University Health Network","funders":"","keywords":"Medicine; Dermatology; Chronic hepatitis; Hair dyes; Ingredient; Cosmetics; Pathology; Immunology; Chemistry","score_opus":0.10279670906963671,"score_gpt":0.3694660394601191,"score_spread":0.26666933039048235,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380568963","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.79103863,0.0002844971,0.00003986531,0.0067303856,0.0031664704,0.0008851864,0.0005525757,0.00046442414,0.19683793],"genre_scores_gemma":[0.8274251,0.00006541521,0.000033369924,0.16869467,0.0009501415,0.00012509494,0.00015461913,0.00006093119,0.002490654],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977861,0.0002205438,0.00025199624,0.00045983755,0.0001881063,0.0010933876],"domain_scores_gemma":[0.9985258,0.000092195776,0.000085020736,0.0003456686,0.00007802625,0.0008732627],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00042092762,0.000295489,0.00027827773,0.00039411293,0.0007041213,0.00004921032,0.00039630802,0.00047846927,0.00010125986],"category_scores_gemma":[0.000016852668,0.00033848453,0.00017195089,0.0007614081,0.00016384308,0.00019625176,0.00004963267,0.00093874725,0.0051701753],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009105902,0.00016274904,0.0027702446,0.0001258546,0.00048297344,0.00032721166,0.010226914,0.00061958004,0.040020786,0.0025166404,0.47405252,0.46860346],"study_design_scores_gemma":[0.0005945278,0.000052441486,0.016396204,0.00001994002,0.000067309826,0.0000017336944,0.0012113682,0.004804856,0.01698994,0.004516417,0.9548517,0.0004935675],"about_ca_topic_score_codex":0.013939871,"about_ca_topic_score_gemma":0.021544205,"teacher_disagreement_score":0.48079917,"about_ca_system_score_codex":0.0003831776,"about_ca_system_score_gemma":0.00040478658,"threshold_uncertainty_score":0.9999067},"labels":[],"label_agreement":null},{"id":"W4382139144","doi":"10.22374/cjgim.v18i1.657","title":"A Massive Acetaminophen Overdose with Unusual Pharmacokinetics","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of General Internal Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Pharmacokinetics; Acetaminophen; Medicine; Plasma concentration; Humanities; Pharmacology; Philosophy","score_opus":0.11736648988041119,"score_gpt":0.4100289120125563,"score_spread":0.2926624221321451,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382139144","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9746897,0.00053673505,0.0004118887,0.0079628555,0.0051849424,0.00024304059,0.000045556415,0.000033795288,0.010891456],"genre_scores_gemma":[0.9858631,0.00021426876,0.000119505945,0.0035371482,0.00307806,0.00000859747,0.000012040025,0.0000343862,0.0071329274],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981314,0.00029077928,0.00053707376,0.00018720735,0.00028775985,0.00056579703],"domain_scores_gemma":[0.9977692,0.0001562259,0.00036336033,0.00011981234,0.00034511252,0.0012463358],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008909548,0.000242516,0.00039261693,0.0007264366,0.00021692063,0.000023541437,0.0003959565,0.00021841838,0.0016262574],"category_scores_gemma":[0.00019255975,0.0001825395,0.00009225775,0.00058415474,0.00037314245,0.00015803405,0.000023886176,0.0013813644,0.00010322603],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027854792,0.00015941184,0.051281344,0.00023068773,0.0024386488,0.021157218,0.011002364,0.0153283905,0.30425775,0.0032911524,0.4501135,0.13795406],"study_design_scores_gemma":[0.009575881,0.0034180454,0.013478669,0.00055444613,0.00065281766,0.0030717652,0.0010543067,0.008934695,0.103792295,0.0015263672,0.853275,0.00066573336],"about_ca_topic_score_codex":0.0035482394,"about_ca_topic_score_gemma":0.0034109137,"teacher_disagreement_score":0.40316147,"about_ca_system_score_codex":0.00028029474,"about_ca_system_score_gemma":0.0006389869,"threshold_uncertainty_score":0.9992864},"labels":[],"label_agreement":null},{"id":"W4383873240","doi":"10.1080/19490976.2023.2231590","title":"Phenylpropionic acid produced by gut microbiota alleviates acetaminophen-induced hepatotoxicity","year":2023,"lang":"en","type":"article","venue":"Gut Microbes","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health; Ministry of Health, British Columbia; National Research Foundation; National Center for Complementary and Integrative Health; University of Chicago; Purdue University; Chicago Community Trust","keywords":"Gut flora; Acetaminophen; Metabolite; Biology; CYP2E1; Cecum; Drug metabolism; Metabolism; Pharmacology; In vivo; Liver injury; Microbiology; Biochemistry; Cytochrome P450","score_opus":0.12543079580242464,"score_gpt":0.4039449844468337,"score_spread":0.278514188644409,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383873240","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98897827,0.00087543216,0.000043272572,0.0027161993,0.0027682714,0.0017513,0.00032841918,0.0012156836,0.0013231257],"genre_scores_gemma":[0.9912853,0.00075405784,0.00015350191,0.0019487223,0.000580804,0.00032395497,0.0003153823,0.000115325005,0.0045229094],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9954509,0.0008651033,0.00078795204,0.0011727519,0.00027791568,0.0014453745],"domain_scores_gemma":[0.9981665,0.00023938378,0.00032622652,0.0006862725,0.00019657545,0.00038503556],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001371155,0.0007052537,0.0006838059,0.00036781616,0.0010762895,0.00012236957,0.00078826974,0.0010679633,0.0011717108],"category_scores_gemma":[0.00023820858,0.0007100167,0.0003137917,0.0011934693,0.00025215722,0.00036586757,0.00037618115,0.0017780339,0.005294962],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015526259,0.0003987221,0.0019812426,0.00017342073,0.0002509303,0.00003388697,0.0008783986,0.000022618426,0.9434427,0.00009123298,0.045226745,0.0073448652],"study_design_scores_gemma":[0.0015458916,0.00015988434,0.0021011736,0.000049102946,0.000110379435,0.000043845153,0.00014385827,0.00037533164,0.86680394,0.0002635785,0.12765223,0.00075076387],"about_ca_topic_score_codex":0.00017193382,"about_ca_topic_score_gemma":0.000079639976,"teacher_disagreement_score":0.08242548,"about_ca_system_score_codex":0.00027702947,"about_ca_system_score_gemma":0.00019874396,"threshold_uncertainty_score":0.9997414},"labels":[],"label_agreement":null},{"id":"W4384626589","doi":"10.1111/1751-2980.13205","title":"Mapping the incidence of drug‐induced liver injury: A systematic review and meta‐analysis","year":2023,"lang":"en","type":"review","venue":"Journal of Digestive Diseases","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Natural Science Foundation of China","keywords":"Medicine; Meta-analysis; Incidence (geometry); Drug; Liver injury; MEDLINE; Systematic review; Pharmacology; Internal medicine","score_opus":0.2998789666593968,"score_gpt":0.4734881530714648,"score_spread":0.17360918641206802,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384626589","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00018557972,0.9966309,0.000014569838,0.00018311867,0.00021940249,0.0023194219,0.00039593808,0.000020511965,0.00003055311],"genre_scores_gemma":[0.0028859568,0.99609286,0.000009063078,0.00041172307,0.00011098511,0.00027379952,0.000010301975,0.000032981363,0.00017235105],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99334973,0.0038951514,0.0018092796,0.00027453355,0.00040178065,0.00026950604],"domain_scores_gemma":[0.9918987,0.0032505859,0.0038117506,0.00030774926,0.00047884881,0.00025232285],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0027570163,0.0004723524,0.0058035958,0.00067359523,0.00023701091,0.000035698344,0.0005918685,0.00027871082,0.0001353335],"category_scores_gemma":[0.0015968553,0.0002677356,0.0028559742,0.0017562099,0.00018854527,0.00020157339,0.00016129029,0.0013559894,0.00002785719],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025326577,0.0001521849,0.00003921161,0.82171243,0.17175816,0.000082983715,0.00039925135,0.00000693972,0.000002493632,0.000052718813,0.000253952,0.0055143503],"study_design_scores_gemma":[0.00010182526,0.00007903187,0.000072257346,0.06073438,0.93058795,0.00008086744,0.00015154306,0.000012944457,0.000011282645,0.00007077059,0.007814506,0.00028262005],"about_ca_topic_score_codex":0.00002567677,"about_ca_topic_score_gemma":0.000006464688,"teacher_disagreement_score":0.76097804,"about_ca_system_score_codex":0.00011089206,"about_ca_system_score_gemma":0.0003990314,"threshold_uncertainty_score":0.99997747},"labels":[],"label_agreement":null},{"id":"W4385294451","doi":"10.1111/apa.16920","title":"Paediatric acute hepatitis and therapeutic doses of paracetamol","year":2023,"lang":"en","type":"article","venue":"Acta Paediatrica","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Acute hepatitis; Intensive care medicine; Hepatitis; Internal medicine","score_opus":0.08575452509914558,"score_gpt":0.39461306977918426,"score_spread":0.3088585446800387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385294451","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935342,0.0013171019,0.000023326218,0.001411335,0.0010844179,0.0005421455,0.000129058,0.00026868065,0.0016897016],"genre_scores_gemma":[0.9863015,0.012003393,0.00007138398,0.00058265746,0.00044305672,0.00009522027,0.00002914737,0.000029875351,0.0004437808],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.99818045,0.00040792627,0.0003886465,0.00034003035,0.00021123022,0.00047172734],"domain_scores_gemma":[0.9984488,0.0008486049,0.00021950711,0.0002157094,0.000074860436,0.00019253141],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006804821,0.0002289455,0.00033779233,0.00038078523,0.00027281867,0.000019491343,0.00021892926,0.00042617004,0.00027672815],"category_scores_gemma":[0.00011734456,0.00021908528,0.00012385761,0.0012196928,0.00014244486,0.00012957217,0.00012617835,0.00063572085,0.00024066417],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00056961284,0.0005434039,0.5035535,0.00041289444,0.0010773237,0.00016414461,0.0033065756,0.00016034924,0.13159859,0.0013381914,0.020780183,0.33649522],"study_design_scores_gemma":[0.00701563,0.0013885273,0.41130465,0.000029325438,0.0026793138,0.00016130743,0.0004262317,0.011266709,0.12650122,0.010095239,0.42725042,0.001881416],"about_ca_topic_score_codex":0.00008111034,"about_ca_topic_score_gemma":0.00001461337,"teacher_disagreement_score":0.40647024,"about_ca_system_score_codex":0.0000351986,"about_ca_system_score_gemma":0.00007727359,"threshold_uncertainty_score":0.8934038},"labels":[],"label_agreement":null},{"id":"W4385521495","doi":"10.3390/vetsci10080500","title":"Hypoadrenocorticism in a Dog Following Recovery from Alpha-Amanitin Intoxication","year":2023,"lang":"en","type":"article","venue":"Veterinary Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Alpha (finance); Chemistry; Medicine; Clinical psychology","score_opus":0.31774732807672523,"score_gpt":0.47781153802205667,"score_spread":0.16006420994533144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385521495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99133646,0.00011673164,0.000056690464,0.00077023706,0.0023891393,0.00034704962,0.000023265298,0.00021499167,0.0047454233],"genre_scores_gemma":[0.9982139,0.00014882762,0.00027960155,0.00065420574,0.00018314709,0.00012149885,0.00002547544,0.000010595009,0.00036276368],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980875,0.00047382418,0.00032846152,0.00044761103,0.0002101815,0.00045241907],"domain_scores_gemma":[0.9991624,0.00047725762,0.00010287485,0.00014238329,0.000016051208,0.0000990492],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015915057,0.000157888,0.00018790805,0.00038685856,0.00047816127,0.00006103858,0.00035248155,0.0002199084,0.0003132572],"category_scores_gemma":[0.00015767186,0.00015878116,0.00009258743,0.0012050907,0.00017606492,0.00050534104,0.00012269893,0.00043708063,0.0007401688],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001590881,0.00023363164,0.034141034,0.000031131116,0.00007016242,0.0004481581,0.0035827043,0.0012951836,0.77447826,0.00044695832,0.0006340239,0.18447965],"study_design_scores_gemma":[0.0040903105,0.003224749,0.59671456,0.00030138163,0.00014180406,0.00012821732,0.003787832,0.058854066,0.14150263,0.060577173,0.12874483,0.0019324188],"about_ca_topic_score_codex":0.00039043694,"about_ca_topic_score_gemma":0.00008181646,"teacher_disagreement_score":0.63297564,"about_ca_system_score_codex":0.000084121704,"about_ca_system_score_gemma":0.00008579363,"threshold_uncertainty_score":0.9513619},"labels":[],"label_agreement":null},{"id":"W4385666813","doi":"10.1001/jamanetworkopen.2023.27739","title":"Management of Acetaminophen Poisoning in the US and Canada","year":2023,"lang":"en","type":"article","venue":"JAMA Network Open","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":85,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Queen's University; University of Calgary","funders":"","keywords":"Acetaminophen; Medicine; Guideline; Ingestion; Emergency department; Nomogram; Emergency medicine; Medical emergency; Anesthesia; Internal medicine; Psychiatry","score_opus":0.113584847101308,"score_gpt":0.4033121859741877,"score_spread":0.2897273388728797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385666813","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97198117,0.00014467476,0.000005401537,0.0030376727,0.0004885632,0.0008017973,0.000009919427,0.000015679212,0.023515094],"genre_scores_gemma":[0.9966015,0.0003796759,0.00007597335,0.0018381784,0.0001324588,0.000120452816,0.000012504872,0.000008334845,0.0008309219],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986777,0.0005303922,0.00020982817,0.0001669491,0.00011625053,0.00029893641],"domain_scores_gemma":[0.9994277,0.00028369468,0.00008580226,0.00014002639,0.00001555469,0.00004725696],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021361404,0.000095539224,0.00015409762,0.0000325348,0.00021306897,0.00004253847,0.00043623868,0.000120997574,0.00008815147],"category_scores_gemma":[0.000014137612,0.0000780927,0.000017301467,0.00042259783,0.000040283026,0.00010671506,0.00029903863,0.00046721075,0.00001348633],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00095197617,0.00018868427,0.5230916,0.00043584424,0.0006259926,0.0009532037,0.0059083807,0.048737597,0.0005809009,0.015201475,0.10241457,0.30090976],"study_design_scores_gemma":[0.0019577888,0.000059728445,0.6370221,0.00014552216,0.00007294213,0.00001677206,0.0014285138,0.008625194,0.0008090718,0.0018534029,0.34777573,0.00023326949],"about_ca_topic_score_codex":0.11520126,"about_ca_topic_score_gemma":0.1660803,"teacher_disagreement_score":0.30067647,"about_ca_system_score_codex":0.000049587114,"about_ca_system_score_gemma":0.00005892683,"threshold_uncertainty_score":0.8906907},"labels":[],"label_agreement":null},{"id":"W4385791507","doi":"10.1136/ebm-2023-pod.74","title":"74 Acetaminophen (paracetamol) deprescribing in long-term care: case series from Edmonton, Canada","year":2023,"lang":"en","type":"article","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Acetaminophen; Medicine; Deprescribing; Adverse effect; Pregabalin; Anesthesia; Codeine; Polypharmacy; Internal medicine; Morphine","score_opus":0.09655732999529096,"score_gpt":0.3773577201529909,"score_spread":0.2808003901577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385791507","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9897005,0.00049370056,0.00003999266,0.0008100039,0.0021450617,0.0007124568,0.00018061373,0.00029161805,0.0056260778],"genre_scores_gemma":[0.9958281,0.00017585154,0.000064490465,0.00095866347,0.00030871131,0.0001558359,0.00018258826,0.000036441837,0.0022893054],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976086,0.00051187223,0.0004454978,0.0005162707,0.00021134599,0.0007064018],"domain_scores_gemma":[0.9989394,0.0003165812,0.00010172393,0.00030503652,0.00007241145,0.0002648672],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004200223,0.00031007576,0.00035129255,0.00017447062,0.00045118004,0.000045893674,0.0002557229,0.0004509355,0.0012557408],"category_scores_gemma":[0.00007715125,0.00032502474,0.00007412808,0.0005283506,0.000089335634,0.00032951133,0.00016240627,0.0010339316,0.00020963808],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00084335485,0.0002626947,0.7531941,0.00040131985,0.0004876541,0.050413948,0.010278653,0.0043235114,0.062325336,0.00046575454,0.013598736,0.10340494],"study_design_scores_gemma":[0.008396444,0.00026427556,0.31823927,0.00017468618,0.00045344967,0.0032711995,0.01126881,0.006328199,0.5759819,0.0008423191,0.07205378,0.0027256606],"about_ca_topic_score_codex":0.56339353,"about_ca_topic_score_gemma":0.9638546,"teacher_disagreement_score":0.51365656,"about_ca_system_score_codex":0.00039110004,"about_ca_system_score_gemma":0.0004163459,"threshold_uncertainty_score":0.9999202},"labels":[],"label_agreement":null},{"id":"W4386484155","doi":"10.1016/j.msksp.2023.102856","title":"Barriers and facilitators to reducing paracetamol use in low back pain: A qualitative study","year":2023,"lang":"en","type":"article","venue":"Musculoskeletal Science and Practice","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Deprescribing; Medicine; Qualitative research; Thematic analysis; Health care; Psychological intervention; Health professionals; Polypharmacy; Nursing; Intensive care medicine","score_opus":0.15556743545582288,"score_gpt":0.4962282212950001,"score_spread":0.34066078583917725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386484155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99374205,0.0000318011,0.000045607296,0.003369526,0.00039442716,0.0012736573,0.000017148932,0.00006792291,0.0010578436],"genre_scores_gemma":[0.99758923,0.00007406026,0.00018582921,0.0016705141,0.00004690717,0.00015131806,0.0000019182419,0.000010974912,0.0002692194],"study_design_codex":"qualitative","study_design_gemma":"qualitative","domain_scores_codex":[0.99409544,0.0038412903,0.000326421,0.00069642585,0.00042710145,0.00061331445],"domain_scores_gemma":[0.99513865,0.0038278652,0.00010717149,0.00018783766,0.00018038011,0.0005580831],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.023510866,0.00020743124,0.00023317504,0.00041994706,0.00078387186,0.00016767776,0.0001937048,0.00014891115,0.00009752155],"category_scores_gemma":[0.016583027,0.00019810848,0.00003259366,0.0024622572,0.0005267449,0.0018944216,0.00019705048,0.0007214597,0.00021301616],"study_design_candidate":"qualitative","study_design_consensus":"qualitative","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020110337,0.00085937,0.06606464,0.00061682984,0.00022218881,0.0003272612,0.63365906,0.0018946916,0.08546878,0.0008404777,0.0024175402,0.20561811],"study_design_scores_gemma":[0.0050448077,0.003998107,0.11164961,0.00021283298,0.00019215027,0.00010547708,0.727073,0.014897147,0.0046318825,0.00088277034,0.12933706,0.0019751159],"about_ca_topic_score_codex":0.0010888173,"about_ca_topic_score_gemma":0.0002895308,"teacher_disagreement_score":0.203643,"about_ca_system_score_codex":0.00012334528,"about_ca_system_score_gemma":0.00019469415,"threshold_uncertainty_score":0.9917007},"labels":[],"label_agreement":null},{"id":"W4386564012","doi":"10.3138/canlivj-2023-0004","title":"Combination vardenifil and tadalifil drug induced liver injury; case report and review of the literature of liver injury associated with phosphodiesterase type 5 inhibitors","year":2023,"lang":"en","type":"article","venue":"Canadian Liver Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Vardenafil; Tadalafil; Medicine; Cholestasis; Liver injury; Erectile dysfunction; cGMP-specific phosphodiesterase type 5; Internal medicine; Gastroenterology; Surgery","score_opus":0.05319292872193297,"score_gpt":0.33802155571223363,"score_spread":0.28482862699030065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386564012","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924408,0.0052040946,4.4578255e-7,0.00065782916,0.00078987714,0.00049382204,0.00018321887,0.0000159875,0.00021391138],"genre_scores_gemma":[0.988573,0.009672729,0.000011020502,0.0010316079,0.000095107345,0.000009179231,0.000022930097,0.000019025947,0.0005653728],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.99815047,0.0007184175,0.00043788523,0.00020561837,0.00020363272,0.00028398447],"domain_scores_gemma":[0.9982407,0.00016040148,0.00051357754,0.00015592469,0.00056256354,0.00036680908],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016254591,0.0001912942,0.00030555122,0.0002587466,0.00047653037,0.000039635834,0.00011791249,0.00029320846,0.00015883808],"category_scores_gemma":[0.00036869862,0.00014944606,0.00006686884,0.00079887017,0.00018841852,0.00023385182,0.000052473482,0.0012133911,0.0000042290594],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002399192,0.001191644,0.17434697,0.0157943,0.0040562022,0.20796551,0.068658404,0.000050754297,0.038306933,0.0013466622,0.311096,0.17478743],"study_design_scores_gemma":[0.012508819,0.004176051,0.29885593,0.050616182,0.005071263,0.2207642,0.0032806613,0.0028537707,0.25310588,0.0017662571,0.1428188,0.0041821813],"about_ca_topic_score_codex":0.0044133156,"about_ca_topic_score_gemma":0.009686466,"teacher_disagreement_score":0.21479894,"about_ca_system_score_codex":0.00018875154,"about_ca_system_score_gemma":0.000585761,"threshold_uncertainty_score":0.6671642},"labels":[],"label_agreement":null},{"id":"W4386726580","doi":"10.1080/15563650.2023.2256469","title":"A food product as a potential serious cause of liver injury","year":2023,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Kingston General Hospital; Queen's University","funders":"","keywords":"Liver injury; Medicine; Drug; Medical prescription; Epigastric pain; Food and drug administration; Intensive care medicine; Internal medicine; Pharmacology","score_opus":0.2727009108758021,"score_gpt":0.5115284544814446,"score_spread":0.23882754360564246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386726580","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98758066,0.00017959284,0.00003923399,0.00253736,0.005658112,0.001100504,0.00009806702,0.00037505708,0.0024314343],"genre_scores_gemma":[0.9926268,0.0010019212,0.00009060966,0.0032951704,0.0011571447,0.00016341843,0.000029802455,0.000042416832,0.0015927398],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99539685,0.0018871707,0.0010992496,0.0006964592,0.00020452133,0.0007157578],"domain_scores_gemma":[0.997694,0.0009437062,0.00039163162,0.00044075254,0.0001804123,0.00034947175],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00276219,0.0002856417,0.0006987197,0.00027246532,0.00026692246,0.000012632229,0.00043230646,0.001181618,0.0015584155],"category_scores_gemma":[0.0015915526,0.00028747093,0.00034856913,0.0007530007,0.00070435886,0.00012382683,0.00031424125,0.001835365,0.0023003304],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009993546,0.0063479915,0.037952226,0.00062153983,0.0028955415,0.0015044175,0.0016688072,0.0008169345,0.2936254,0.010731887,0.06107766,0.57276404],"study_design_scores_gemma":[0.008733187,0.019499095,0.12480589,0.00006998796,0.0010651747,0.0005793031,0.00024167057,0.0054422705,0.26940814,0.018682389,0.54984474,0.0016281627],"about_ca_topic_score_codex":0.000037445505,"about_ca_topic_score_gemma":0.00007593132,"teacher_disagreement_score":0.5711359,"about_ca_system_score_codex":0.00005806595,"about_ca_system_score_gemma":0.00030263647,"threshold_uncertainty_score":0.99995774},"labels":[],"label_agreement":null},{"id":"W4387114975","doi":"10.4212/cjhp.3415","title":"Acetaminophen Dose Considerations in Frail and Malnourished Elderly Patients: A Case Report of Hepatotoxicity with Therapeutic Doses","year":2023,"lang":"en","type":"article","venue":"The Canadian Journal of Hospital Pharmacy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Hôpital Notre-Dame","funders":"","keywords":"Acetaminophen; Medicine; Intensive care medicine; Pharmacology","score_opus":0.08611810898323531,"score_gpt":0.36740399656599554,"score_spread":0.28128588758276024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387114975","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993767,0.0003601618,0.0000071682766,0.0039243153,0.00073141034,0.00068320346,0.00006660102,0.000017274573,0.00044284717],"genre_scores_gemma":[0.9990716,0.00007513865,0.000043061256,0.00055188074,0.00012340341,0.000024827546,0.0000061295827,0.000023255987,0.000080703045],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998052,0.0004911448,0.0006542114,0.00018667792,0.00019987815,0.00041606845],"domain_scores_gemma":[0.99815303,0.00040749932,0.00050040946,0.00016834703,0.00034394546,0.00042675107],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013606065,0.00021022758,0.00034042855,0.0003922644,0.00052423717,0.00005883162,0.0001712189,0.00013221202,0.00023179718],"category_scores_gemma":[0.00024051194,0.00015688283,0.00008546505,0.00050507847,0.0004218077,0.00034402974,0.000025662364,0.0010931658,0.000009304844],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00061829644,0.000640052,0.8663935,0.00015958147,0.0009371145,0.08631826,0.018790951,0.0013990493,0.0023348632,0.00067111285,0.003460519,0.01827669],"study_design_scores_gemma":[0.04711284,0.009356133,0.651065,0.00060799904,0.0023195082,0.105489634,0.0071649426,0.004768607,0.096988425,0.025109055,0.046950046,0.003067816],"about_ca_topic_score_codex":0.009021245,"about_ca_topic_score_gemma":0.0330674,"teacher_disagreement_score":0.21532851,"about_ca_system_score_codex":0.00014694249,"about_ca_system_score_gemma":0.00096607185,"threshold_uncertainty_score":0.9975778},"labels":[],"label_agreement":null},{"id":"W4387150447","doi":"10.56499/jppres23.1732_11.6.1002","title":"Hepatoprotective study of Indonesian water kefir against CCl4-induced liver injury in rats","year":2023,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmacognosy Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Encana (Canada)","funders":"","keywords":"CCL4; Carbon tetrachloride; Liver injury; Kefir; Metabolite; Chemistry; Pharmacology; Biochemistry; Medicine; Lactic acid; Biology; Organic chemistry","score_opus":0.3808855873334365,"score_gpt":0.5441619935910128,"score_spread":0.16327640625757628,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387150447","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99275035,0.00019763384,0.0000073325814,0.000812169,0.0021055222,0.0028472198,0.00003880922,0.00009050498,0.0011504736],"genre_scores_gemma":[0.996577,0.0015215538,0.000018793964,0.00029742182,0.000989747,0.0002702037,0.000009234116,0.000095281124,0.00022072782],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.98725444,0.0067680846,0.0019374274,0.0006543354,0.0017632464,0.0016224459],"domain_scores_gemma":[0.99577916,0.0010303853,0.0006038828,0.00034546046,0.0015559786,0.00068510656],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.015276274,0.000525663,0.0010106529,0.003560712,0.00062693714,0.000072657545,0.0012327954,0.0003942631,0.000879762],"category_scores_gemma":[0.0003965152,0.0004427581,0.00034544404,0.0033759808,0.00028362198,0.0009310862,0.00056509225,0.0073527927,0.0004608228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005750577,0.00399158,0.0358615,0.00024899695,0.0005283231,0.0021366547,0.009954297,0.0004313108,0.86519426,0.000008462693,0.0012560916,0.07463796],"study_design_scores_gemma":[0.01177858,0.0014798506,0.0054713315,0.0001110392,0.0001462987,0.00008607061,0.002422143,0.005349783,0.9573425,0.00020290814,0.015144527,0.0004649883],"about_ca_topic_score_codex":0.0005446884,"about_ca_topic_score_gemma":0.00008592685,"teacher_disagreement_score":0.09214824,"about_ca_system_score_codex":0.00047472515,"about_ca_system_score_gemma":0.00053644355,"threshold_uncertainty_score":0.9998024},"labels":[],"label_agreement":null},{"id":"W4388068261","doi":"10.7748/en.31.6.10.s4","title":"New protocol for treating paracetamol overdose","year":2023,"lang":"en","type":"article","venue":"Emergency Nurse","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"World Federation of Science Journalists","funders":"","keywords":"Medicine; Protocol (science); Drug overdose; Emergency medicine; Medical emergency; Anesthesia; Intensive care medicine; Poison control; Alternative medicine","score_opus":0.2195760380191404,"score_gpt":0.5222110663782505,"score_spread":0.30263502835911016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388068261","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.24151123,0.00007385147,0.007021398,0.0072154915,0.018404212,0.6177501,0.00029111336,0.0037115605,0.10402102],"genre_scores_gemma":[0.090488926,0.000039706036,0.0014663334,0.0006766177,0.0038415613,0.78755563,0.00011399179,0.00015735276,0.115659855],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982328,0.00022042006,0.00043132828,0.00037910204,0.00014888043,0.0005874719],"domain_scores_gemma":[0.9991524,0.00013123595,0.00016219265,0.00022087994,0.00007145814,0.0002618294],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0006502541,0.00024183202,0.00022122992,0.00015129415,0.0005007047,0.000012960846,0.00021258484,0.0003582707,0.0058027105],"category_scores_gemma":[0.00017375666,0.00024114392,0.0001890042,0.00060355105,0.000030636736,0.00017630776,0.00002980454,0.00047200776,0.0013514267],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014029094,0.0004782602,0.011165652,0.00040938758,0.00023092692,0.00002589548,0.0032189607,0.001189418,0.07833736,0.0043235654,0.60833955,0.29087815],"study_design_scores_gemma":[0.0032521433,0.00024608063,0.002539167,0.00002572225,0.000069470756,0.0000065545414,0.00016204179,0.008055177,0.071986966,0.005979929,0.9072823,0.00039446304],"about_ca_topic_score_codex":0.000077622055,"about_ca_topic_score_gemma":0.000045884826,"teacher_disagreement_score":0.29894274,"about_ca_system_score_codex":0.000060970462,"about_ca_system_score_gemma":0.00011099985,"threshold_uncertainty_score":0.9994261},"labels":[],"label_agreement":null},{"id":"W4388157271","doi":"10.1002/vrc2.756","title":"Manifestation of oculorenal syndrome in a dog chronically receiving zonisamide","year":2023,"lang":"en","type":"article","venue":"Veterinary Record Case Reports","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Zonisamide; Proteinuria; Histopathology; Uveitis; Nephropathy; Metabolic acidosis; Pediatrics; Labrador Retriever; Internal medicine; Surgery; Pathology; Epilepsy; Kidney; Diabetes mellitus; Endocrinology; Ophthalmology","score_opus":0.16699484814999263,"score_gpt":0.43827369721790044,"score_spread":0.2712788490679078,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388157271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99517167,0.000054572592,0.000050558385,0.00015134152,0.0018459015,0.0005523026,0.00001670125,0.00018747996,0.001969505],"genre_scores_gemma":[0.99881995,0.00022154128,0.00020928655,0.000072290706,0.000090828864,0.00014919652,0.000037726284,0.000029848454,0.00036930898],"study_design_codex":"case_report","study_design_gemma":"case_report","domain_scores_codex":[0.9976268,0.0004941315,0.0008493369,0.0004281927,0.000169135,0.0004324121],"domain_scores_gemma":[0.99882954,0.0002960835,0.00039967865,0.00027412374,0.000061859435,0.000138684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017740305,0.00020534359,0.0003342904,0.0003752455,0.00016702806,0.0000152066095,0.000068879854,0.00035438073,0.00039619932],"category_scores_gemma":[0.00017415319,0.00022545429,0.0001181199,0.0006974582,0.00009147625,0.00021826728,0.000105308434,0.0006785388,0.000059854465],"study_design_candidate":"case_report","study_design_consensus":"case_report","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037456717,0.00033000027,0.024417562,0.0005369848,0.00011076495,0.7816465,0.0008054507,0.0010556381,0.094801605,0.000052209904,0.0002624219,0.09560628],"study_design_scores_gemma":[0.0016809456,0.002849838,0.086755924,0.00040458672,0.00012129899,0.83439595,0.00040862904,0.009738014,0.01489913,0.0024739378,0.045394737,0.0008769872],"about_ca_topic_score_codex":0.00060207734,"about_ca_topic_score_gemma":0.00024932853,"teacher_disagreement_score":0.09472929,"about_ca_system_score_codex":0.00017536044,"about_ca_system_score_gemma":0.00012476914,"threshold_uncertainty_score":0.9193759},"labels":[],"label_agreement":null},{"id":"W4388540516","doi":"10.1016/j.anai.2023.08.056","title":"SAFETY OF ANTI-SARS-COV-2 MONOCLONAL ANTIBODY THERAPIES: CLINICAL CHARACTERISTICS AND OUTCOMES OF ADVERSE DRUG REACTIONS","year":2023,"lang":"en","type":"article","venue":"Annals of Allergy Asthma & Immunology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Cégep de Saint-Laurent","funders":"","keywords":"Medicine; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Monoclonal antibody; Drug; Adverse effect; Virology; Drug reaction; Monoclonal; Antibody; Intensive care medicine; Pharmacology; Immunology; Internal medicine; Infectious disease (medical specialty)","score_opus":0.1728031734571845,"score_gpt":0.4711927993974789,"score_spread":0.2983896259402944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388540516","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99506104,0.00044516442,0.00005313536,0.0020279964,0.0012952787,0.00029974268,0.00022162343,0.00007376558,0.0005222545],"genre_scores_gemma":[0.98262477,0.016330458,0.00010638283,0.0004915688,0.0000750791,0.000015595122,0.000094437935,0.000026084945,0.00023562173],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.996799,0.0009247475,0.0013613888,0.00034551244,0.0001515334,0.00041784998],"domain_scores_gemma":[0.9974084,0.0009446303,0.0009091506,0.00033996356,0.0003353251,0.00006255783],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0017394806,0.00026457847,0.00092402525,0.0003430185,0.00017872793,0.0000027319456,0.00029762284,0.00061274075,0.00013909393],"category_scores_gemma":[0.00029413673,0.0002611886,0.00030777667,0.00038690897,0.0009296574,0.0001618604,0.00018204346,0.00084077683,0.000042397758],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022651125,0.001291178,0.042940028,0.00014952823,0.004815445,0.000030038436,0.002081229,0.00007838911,0.91420543,0.008598713,0.00068398303,0.022860926],"study_design_scores_gemma":[0.0013675542,0.0003726953,0.63695186,0.00003999342,0.000014318186,0.00001702043,0.0003890895,0.0003130768,0.21519685,0.0006611143,0.14446133,0.00021510654],"about_ca_topic_score_codex":0.00021707865,"about_ca_topic_score_gemma":0.000038900598,"teacher_disagreement_score":0.6990086,"about_ca_system_score_codex":0.00001001295,"about_ca_system_score_gemma":0.00010804825,"threshold_uncertainty_score":0.999984},"labels":[],"label_agreement":null},{"id":"W4389298639","doi":"10.1097/meg.0000000000002689","title":"Association of BMI with mortality in drug-induced liver injury","year":2023,"lang":"en","type":"article","venue":"European Journal of Gastroenterology & Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"First Quantum Minerals (Canada)","funders":"","keywords":"Medicine; Underweight; Overweight; Internal medicine; Body mass index; Proportional hazards model; Cause of death; Gastroenterology; Liver transplantation; Obesity; Mortality rate; Transplantation; Disease","score_opus":0.08405171077723489,"score_gpt":0.36877833601170723,"score_spread":0.28472662523447234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389298639","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99528456,0.00002454158,0.00013999881,0.0014323058,0.0014771062,0.00023726212,0.000022760132,0.00004639831,0.001335061],"genre_scores_gemma":[0.9982824,0.00023023844,0.00013163881,0.00095993263,0.00021002321,0.0000068491067,0.000007943285,0.000034489167,0.00013652873],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9919282,0.0058027986,0.0011023959,0.00027542043,0.00024916243,0.0006419852],"domain_scores_gemma":[0.99771184,0.00030287614,0.0013344663,0.00019744333,0.00028007955,0.00017328406],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0053225206,0.0002460821,0.00071428623,0.00066265464,0.000101228776,0.000007704117,0.00040035724,0.00022086683,0.00016162617],"category_scores_gemma":[0.00017408741,0.00022559715,0.00016785474,0.00046470133,0.00018431248,0.00018362595,0.00011222648,0.0017221905,0.00011666953],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030092164,0.00032455576,0.9659605,0.000048118858,0.00044351417,0.0013322321,0.0007631262,0.00022453153,0.022324963,0.00005245617,0.0024489984,0.0030677603],"study_design_scores_gemma":[0.007588967,0.0051398776,0.9393336,0.00009445937,0.00041078732,0.00088914135,0.0002929812,0.00077323575,0.024334492,0.00013552232,0.020706972,0.00029991867],"about_ca_topic_score_codex":0.000058960984,"about_ca_topic_score_gemma":0.0008072131,"teacher_disagreement_score":0.026626883,"about_ca_system_score_codex":0.00017811205,"about_ca_system_score_gemma":0.000102200465,"threshold_uncertainty_score":0.9199585},"labels":[],"label_agreement":null},{"id":"W4389541955","doi":"10.1139/cjpp-2023-0253","title":"The role of melatonin in preventing amiodarone-induced rat liver damage","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja","keywords":"Melatonin; Amiodarone; Hepatocyte; Cell damage; Pharmacology; Xanthine oxidase; Programmed cell death; Apoptosis; Endocrinology; Chemistry; Oxidative stress; Internal medicine; Mitochondrion; Reactive oxygen species; Biology; Medicine; Biochemistry; Enzyme","score_opus":0.0644888174168392,"score_gpt":0.36838852990024795,"score_spread":0.30389971248340875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389541955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942401,0.0015609951,0.0000013200196,0.0007200747,0.0024371843,0.00029321553,0.000016140224,0.000012192433,0.00071874587],"genre_scores_gemma":[0.9981348,0.0009164919,0.00001299103,0.00041643908,0.00032411586,0.000020373243,0.0000046346836,0.000016101141,0.00015407566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971762,0.0013270633,0.0006024328,0.00019737807,0.000075309785,0.00062166865],"domain_scores_gemma":[0.998106,0.00087683107,0.00041892217,0.0001025387,0.00013450658,0.00036121957],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019617663,0.00018521406,0.000399358,0.00044647485,0.0005066423,0.000010133316,0.00035271182,0.00043307652,0.0005747225],"category_scores_gemma":[0.000114418996,0.00015605577,0.00011223105,0.0004832965,0.00045487352,0.00015210881,0.000053478958,0.0014876171,0.00003399519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024496525,0.000040960018,0.010357584,0.000057652112,0.00016852345,0.000121653466,0.001571669,0.0003752403,0.9705546,0.0011001541,0.00085583417,0.014551166],"study_design_scores_gemma":[0.0018600521,0.0003341751,0.029615637,0.000030628304,0.00013259499,0.00011976912,0.00065831345,0.0028391886,0.89874035,0.0078226,0.057621606,0.00022508667],"about_ca_topic_score_codex":0.00074567203,"about_ca_topic_score_gemma":0.0031884213,"teacher_disagreement_score":0.07181425,"about_ca_system_score_codex":0.000085447005,"about_ca_system_score_gemma":0.00058845273,"threshold_uncertainty_score":0.6463039},"labels":[],"label_agreement":null},{"id":"W4391294242","doi":"10.1016/j.biopha.2024.116183","title":"Editor’s Note on “Deaths induced by compassionate use of hydroxychloroquine during the first COVID-19 wave: An estimate” [Biomedicine &amp; Pharmacotherapy, 171 (2024) 116055]","year":2024,"lang":"en","type":"editorial","venue":"Biomedicine & Pharmacotherapy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"","keywords":"Hydroxychloroquine; Coronavirus disease 2019 (COVID-19); Biomedicine; Pharmacotherapy; Medicine; Compassionate Use; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); 2019-20 coronavirus outbreak; Drug repositioning; Pharmacology; Intensive care medicine; Virology; Drug; Internal medicine; Bioinformatics; Clinical trial; Biology","score_opus":0.11147906563759456,"score_gpt":0.46525563677487214,"score_spread":0.35377657113727756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391294242","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.046410907,0.0044495976,0.00027883518,0.016677005,0.92108184,0.004122675,0.0057573467,0.0009883317,0.00023343676],"genre_scores_gemma":[0.026772112,0.018037157,0.00012564533,0.014505218,0.92711085,0.0010955484,0.0033066834,0.0007329903,0.008313768],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9888223,0.0017017031,0.0024999795,0.002335356,0.0027831823,0.001857483],"domain_scores_gemma":[0.9909486,0.0035638788,0.0015863258,0.0014665127,0.0005576753,0.0018769802],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.0037173938,0.0022615604,0.0023381538,0.0017076815,0.0015167426,0.00019135677,0.0015978358,0.0032470478,0.00711178],"category_scores_gemma":[0.00041239522,0.0016785398,0.0006588668,0.002184114,0.0013948597,0.0005747745,0.00026517623,0.008350228,0.0003904842],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0047025713,0.0012414783,0.000019905578,0.001245527,0.0011248703,0.00015612735,0.0014135855,0.00018555878,0.3344333,0.000009008237,0.64848477,0.006983332],"study_design_scores_gemma":[0.013002872,0.0015553185,0.000019776662,0.00057840283,0.0009961524,0.00006506086,0.000051486033,0.0032724817,0.055971134,0.00007985767,0.9229351,0.0014723385],"about_ca_topic_score_codex":0.0014620713,"about_ca_topic_score_gemma":0.00017334487,"teacher_disagreement_score":0.27846214,"about_ca_system_score_codex":0.0016233791,"about_ca_system_score_gemma":0.0012941324,"threshold_uncertainty_score":0.99978316},"labels":[],"label_agreement":null},{"id":"W4391719095","doi":"10.1007/s43678-023-00641-9","title":"Assessing the frequency and types of errors involved in the use of a modified intravenous N-acetylcysteine protocol for acetaminophen overdose","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Emergency Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; St. Michael's Hospital; Western University","funders":"","keywords":"Dosing; Medicine; Protocol (science); acetaminophen overdose; Acetaminophen; Emergency department; Emergency medicine; Acetylcysteine; Anesthesia; Pharmacology","score_opus":0.4923841342226049,"score_gpt":0.5021842543196066,"score_spread":0.009800120097001652,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391719095","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9596848,0.0018269288,0.00068289536,0.006610648,0.0038263788,0.026503868,0.000053377342,0.0000077789755,0.0008033563],"genre_scores_gemma":[0.9972035,0.00007667769,0.0001006085,0.00021042004,0.00040670868,0.0019135711,0.0000028260142,0.000013685111,0.00007199427],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99833995,0.00043731974,0.0007469507,0.00010954995,0.00014018589,0.0002260464],"domain_scores_gemma":[0.99878997,0.0004256502,0.0003215045,0.00011967717,0.00018413473,0.00015908391],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002027108,0.0001319826,0.00029397526,0.00026158796,0.00013219246,0.000010334291,0.0002199807,0.0001579239,0.00033381913],"category_scores_gemma":[0.00059645943,0.00007589831,0.00006976479,0.00040191718,0.00023552828,0.00022310951,0.000008085464,0.00064614846,4.511126e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019593907,0.00091377227,0.056651004,0.012281315,0.002856336,0.0007056699,0.16157874,0.009447908,0.52850235,0.035590306,0.060276378,0.12923683],"study_design_scores_gemma":[0.016411964,0.008580169,0.034079663,0.0057341317,0.002367571,0.0003885246,0.015648855,0.04820296,0.03172259,0.032156307,0.80347455,0.0012327463],"about_ca_topic_score_codex":0.00420894,"about_ca_topic_score_gemma":0.009183947,"teacher_disagreement_score":0.74319816,"about_ca_system_score_codex":0.00006729814,"about_ca_system_score_gemma":0.00060726894,"threshold_uncertainty_score":0.6362686},"labels":[],"label_agreement":null},{"id":"W4391845032","doi":"10.1007/s43678-024-00660-0","title":"N-acetylcysteine for acetaminophen poisoning: translating poison center protocols to the bedside","year":2024,"lang":"en","type":"letter","venue":"Canadian Journal of Emergency Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Atlantic School of Theology; Dalhousie University; University of Toronto","funders":"","keywords":"Acetylcysteine; Acetaminophen; Medicine; Medical emergency; Center (category theory); Chemistry; Pharmacology","score_opus":0.38083578259488665,"score_gpt":0.49423721118218644,"score_spread":0.11340142858729979,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391845032","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001152153,0.0020741862,0.00056122604,0.947546,0.03183997,0.012352758,0.00034493493,0.00002920901,0.004099529],"genre_scores_gemma":[0.031953234,0.00027286547,0.00044239705,0.79214025,0.12760256,0.008737864,0.00034447585,0.00047284365,0.03803351],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.996061,0.00055991916,0.001569953,0.00040432837,0.00040570533,0.0009990708],"domain_scores_gemma":[0.9973532,0.00026942676,0.0006875104,0.00032548042,0.00053337443,0.00083101407],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002624742,0.0005427637,0.0008664295,0.000691968,0.0005603823,0.00002714336,0.00088787783,0.0011414629,0.003911035],"category_scores_gemma":[0.0007370984,0.0003763467,0.00045580964,0.00057040283,0.000132089,0.00012537959,0.00002198672,0.0054886076,0.0001061955],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010070227,0.000013860601,0.0001895363,0.00072753936,0.00045461985,0.0002754008,0.004325874,0.00009357293,0.0015856402,0.0000428558,0.9865738,0.0056165555],"study_design_scores_gemma":[0.0012435458,0.0009627833,0.000020122807,0.0011219837,0.00054570375,0.00012927952,0.00024312473,0.00016621975,0.0006228902,0.0005196531,0.9940588,0.00036589493],"about_ca_topic_score_codex":0.001557713,"about_ca_topic_score_gemma":0.011173631,"teacher_disagreement_score":0.15540577,"about_ca_system_score_codex":0.00039387943,"about_ca_system_score_gemma":0.0011070394,"threshold_uncertainty_score":0.99986887},"labels":[],"label_agreement":null},{"id":"W4391886458","doi":"10.1093/jcag/gwad061.228","title":"A228 RISANKIZUMAB - DRUG INDUCED LIVER INJURY; A CASE REPORT","year":2024,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Drug; Liver injury; Medicine; Pharmacology","score_opus":0.05325613985323041,"score_gpt":0.36024211939780604,"score_spread":0.3069859795445756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391886458","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98100525,0.000053293403,0.000022610577,0.011681803,0.006173622,0.00022292671,0.00007854191,0.000014723204,0.0007472169],"genre_scores_gemma":[0.99651057,0.000029363002,0.000041115974,0.0018246936,0.0005048454,0.000006541869,0.0000025828526,0.000016993354,0.0010632812],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.99723697,0.0012299136,0.00073095225,0.00015221722,0.0002446278,0.00040534325],"domain_scores_gemma":[0.99807507,0.00021055952,0.0009596257,0.00015311966,0.00031223407,0.00028942057],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0031555088,0.00014837804,0.0003276613,0.0004119051,0.00028209735,0.000035990004,0.00026794733,0.0003946507,0.0002865888],"category_scores_gemma":[0.00047484992,0.00012317332,0.00028828697,0.00024791132,0.00007030495,0.00018048754,0.000040937623,0.0016926781,0.00002194806],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024116088,0.0005597229,0.6045076,0.00035703843,0.004785143,0.07293284,0.009072965,0.0008104465,0.022648565,0.0013322663,0.2614206,0.019161174],"study_design_scores_gemma":[0.007331337,0.003241691,0.07442757,0.00045584983,0.0025444115,0.25728306,0.00082488876,0.004832483,0.033194106,0.0031758454,0.6118926,0.00079619937],"about_ca_topic_score_codex":0.00918362,"about_ca_topic_score_gemma":0.28488106,"teacher_disagreement_score":0.5300801,"about_ca_system_score_codex":0.001715137,"about_ca_system_score_gemma":0.0007839048,"threshold_uncertainty_score":0.9974143},"labels":[],"label_agreement":null},{"id":"W4392168991","doi":"10.3138/canlivj-2023-0021","title":"Effects of silymarin use on liver enzymes and metabolic factors in metabolic dysfunction-associated steatotic liver disease: a systematic review and meta-analysis","year":2024,"lang":"en","type":"review","venue":"Canadian Liver Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Meta-analysis; Liver enzyme; Medicine; Liver dysfunction; Fatty liver; Metabolic disease; Liver disease; Internal medicine; Disease; Enzyme; Gastroenterology; Biochemistry; Biology","score_opus":0.17778140125591332,"score_gpt":0.3894350557446317,"score_spread":0.2116536544887184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392168991","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00068679964,0.994763,0.000003391122,0.000048782178,0.00041373834,0.0033350254,0.000701488,0.000025184432,0.000022596007],"genre_scores_gemma":[0.008784507,0.9889108,0.0000053278072,0.00076985476,0.00007082884,0.00030916726,0.000052696523,0.00007026621,0.0010265554],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9916125,0.0053472864,0.0013869508,0.0006504325,0.00034786094,0.0006549971],"domain_scores_gemma":[0.9954143,0.0017411658,0.0009903951,0.00032221372,0.00017066771,0.0013612335],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0019739612,0.00089293293,0.006619432,0.0024583477,0.00034073618,0.00017886021,0.00032101735,0.0007692639,0.00058906287],"category_scores_gemma":[0.00096989796,0.0006436619,0.0020509341,0.001670686,0.00015866211,0.00032961945,0.00007778753,0.0027980686,0.000053973905],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019902614,0.00021115674,0.00021621691,0.73137033,0.25795612,0.0015907174,0.0006061123,0.000014155449,6.686062e-7,0.0012081768,0.0006039122,0.006202549],"study_design_scores_gemma":[0.0002823616,0.0000520295,0.0008009857,0.01678699,0.9222764,0.00012732254,0.000013276143,0.0000885002,0.000008558373,0.000022170427,0.05896319,0.0005782398],"about_ca_topic_score_codex":0.009435117,"about_ca_topic_score_gemma":0.02225062,"teacher_disagreement_score":0.71458334,"about_ca_system_score_codex":0.00043939333,"about_ca_system_score_gemma":0.00084689585,"threshold_uncertainty_score":0.9996015},"labels":[],"label_agreement":null},{"id":"W4392604477","doi":"10.1101/2024.03.06.24303823","title":"Nephroprotective effects of cilastatin in people at risk of acute kidney injury: A systematic review and meta-analysis","year":2024,"lang":"en","type":"review","venue":"medRxiv","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Alberta; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Cilastatin; Medicine; Imipenem; Meta-analysis; Randomized controlled trial; Internal medicine; Observational study; Imipenem/cilastatin; Intensive care medicine; Antibiotics; Antibiotic resistance; Biology; Microbiology","score_opus":0.1029866318736852,"score_gpt":0.4437339892068735,"score_spread":0.3407473573331883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392604477","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005155358,0.98914874,0.00002853916,0.000079104284,0.00021328966,0.00789567,0.0019905919,0.000038506863,0.00009005475],"genre_scores_gemma":[0.001229289,0.99464494,0.000041702457,0.00023264186,0.000019441857,0.0031161488,0.000058564943,0.00005426671,0.0006029859],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99035174,0.006493992,0.0018465071,0.00067632814,0.00028599202,0.0003454388],"domain_scores_gemma":[0.99623084,0.0010092888,0.0018679275,0.00055282697,0.00012106578,0.0002180625],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0036341278,0.0006847819,0.009848486,0.0008993726,0.000102299826,0.000011722061,0.0003547476,0.00073658396,0.00031495525],"category_scores_gemma":[0.0010154616,0.000469309,0.002524652,0.002793398,0.0001520793,0.00007096027,0.00025737207,0.0017810512,0.00009368452],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019420571,0.000091054964,0.000035234512,0.8085066,0.18951084,0.000021362624,0.0004125767,7.655609e-7,0.00003339336,0.000020915824,0.0001255135,0.00122233],"study_design_scores_gemma":[0.0001752673,0.0001365131,0.000008052756,0.028029816,0.95568645,0.000021501328,0.0000049064747,0.000034723973,0.00049623946,0.000080184196,0.014981043,0.00034530123],"about_ca_topic_score_codex":0.00011176162,"about_ca_topic_score_gemma":0.00009876608,"teacher_disagreement_score":0.7804768,"about_ca_system_score_codex":0.00020845623,"about_ca_system_score_gemma":0.00019534865,"threshold_uncertainty_score":0.9997759},"labels":[],"label_agreement":null},{"id":"W4392706606","doi":"10.1002/rcm.9731","title":"Perturbations in human bile acid profiles following drug‐induced liver injury investigated using semitargeted high‐resolution mass spectrometry","year":2024,"lang":"en","type":"article","venue":"Rapid Communications in Mass Spectrometry","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta Hospital; University of Alberta; Université de Montréal; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Université du Québec à Montréal","keywords":"Chemistry; Taurine; Chromatography; Acetaminophen; Mass spectrometry; Liver injury; Glucuronide; Sulfation; Resolution (logic); Tandem mass spectrometry; Drug metabolism; Urine; Pharmacology; Metabolism; Amino acid; Biochemistry","score_opus":0.1245864197593121,"score_gpt":0.40719803119514136,"score_spread":0.28261161143582925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392706606","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9849967,0.005379328,0.0016376289,0.0016676086,0.0013152622,0.0013331745,0.00010528287,0.00053981517,0.0030252344],"genre_scores_gemma":[0.976031,0.0010384639,0.021483755,0.00022416566,0.00022996415,0.00036706374,0.00029915414,0.00008912575,0.00023730412],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99475646,0.0022444122,0.0010205796,0.0007455037,0.0003586144,0.0008744152],"domain_scores_gemma":[0.99743754,0.00075366406,0.00022222393,0.0012817414,0.000090195994,0.00021463445],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.002377949,0.00048995134,0.0005653807,0.003104656,0.0009369415,0.00016337035,0.0011818631,0.0007363145,0.00078525615],"category_scores_gemma":[0.0003232014,0.00056709524,0.00026526532,0.005687029,0.00029473213,0.0007497289,0.00031899312,0.0038328134,0.00009859979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041334057,0.00042717403,0.0070546716,0.00012362647,0.00021060635,0.00004084975,0.0012297665,0.00045883693,0.9803574,0.0085129365,0.00021298401,0.0013297768],"study_design_scores_gemma":[0.002156893,0.00030639285,0.01582016,0.0006840755,0.00034054957,0.00004241972,0.001619111,0.23474985,0.71367514,0.024649903,0.0043605072,0.0015949726],"about_ca_topic_score_codex":0.0007077518,"about_ca_topic_score_gemma":0.0003214896,"teacher_disagreement_score":0.26668227,"about_ca_system_score_codex":0.0019237878,"about_ca_system_score_gemma":0.000322695,"threshold_uncertainty_score":0.9996781},"labels":[],"label_agreement":null},{"id":"W4392787624","doi":"10.1177/1934578x241228944","title":"Hepatoprotective Effects of a Chemically-Characterized Extract from <i>Cistus ladanifer</i> : <i>In Vivo</i> and <i>in Silico</i> Investigations","year":2024,"lang":"en","type":"article","venue":"Natural Product Communications","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"In silico; In vivo; Chemistry; Traditional medicine; Botany; Biochemistry; Biology; Biotechnology; Medicine","score_opus":0.057760400852060724,"score_gpt":0.3766109571789902,"score_spread":0.31885055632692944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392787624","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9785989,0.012550008,0.000018143548,0.005024274,0.0006735057,0.001604667,0.00011873107,0.00014573215,0.0012660208],"genre_scores_gemma":[0.99570936,0.0018293115,0.001119843,0.00054680125,0.00010506092,0.00043394964,0.00006516889,0.00002731157,0.00016316619],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976774,0.0008328458,0.000551926,0.00048603193,0.00014745563,0.00030432898],"domain_scores_gemma":[0.99725723,0.0016809984,0.00013289052,0.00073013466,0.00008977914,0.00010897444],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0007052538,0.00024987047,0.00037416196,0.0002536036,0.00018648483,0.000040780986,0.0004917306,0.0003000564,0.000038033897],"category_scores_gemma":[0.0006242855,0.00025322268,0.00008464263,0.0008288823,0.00040388422,0.00036444733,0.00025339195,0.0023986883,0.000019903217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012290193,0.00031099608,0.002866311,0.00022234056,0.00006879635,0.000012243725,0.0016755271,0.000008739739,0.9797266,0.0007007076,0.00014871308,0.014136116],"study_design_scores_gemma":[0.0012292537,0.000048272082,0.011870131,0.0004206295,0.00009971583,0.0000241661,0.000061600746,0.006520689,0.9443502,0.005836985,0.029160855,0.00037749996],"about_ca_topic_score_codex":0.00069617335,"about_ca_topic_score_gemma":0.0008158632,"teacher_disagreement_score":0.035376403,"about_ca_system_score_codex":0.00015036768,"about_ca_system_score_gemma":0.00014272032,"threshold_uncertainty_score":0.999992},"labels":[],"label_agreement":null},{"id":"W4392798013","doi":"10.1007/s40278-024-54315-7","title":"One lot of Pediatrix Acetaminophen Oral Solution recalled in Canada","year":2024,"lang":"en","type":"article","venue":"Reactions Weekly","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Acetaminophen; Business; Medicine; Pharmacology","score_opus":0.1475419039058673,"score_gpt":0.39964298473658494,"score_spread":0.25210108083071764,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392798013","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9832461,0.0006207329,0.0003749016,0.0027045002,0.003116267,0.0005082859,0.00007867083,0.00011531059,0.009235253],"genre_scores_gemma":[0.99712807,0.00037145807,0.00015246648,0.00012839986,0.00025936085,0.00006623991,0.000026305912,0.000018648172,0.0018490396],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985172,0.00032391745,0.0004197294,0.00025741075,0.00016974166,0.0003119987],"domain_scores_gemma":[0.99929273,0.00030358756,0.000086810396,0.00014784907,0.000056563505,0.00011244101],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006144229,0.00013784484,0.00023312756,0.00023711441,0.00012823968,0.0000131387,0.00011698765,0.00025883372,0.00054832426],"category_scores_gemma":[0.00008252641,0.00015811092,0.00007245361,0.0005627728,0.000050226663,0.0001837936,0.000032902888,0.0010227466,0.00011407291],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007280501,0.0012796473,0.017514909,0.001217301,0.00065947167,0.00016032044,0.0015565144,0.004727286,0.6596362,0.0066063,0.018345881,0.2875681],"study_design_scores_gemma":[0.0026094106,0.0003006208,0.042168923,0.00025285504,0.0004992524,0.000096200354,0.0007908379,0.04844002,0.14246807,0.0024407732,0.75905925,0.0008738057],"about_ca_topic_score_codex":0.5514004,"about_ca_topic_score_gemma":0.67647755,"teacher_disagreement_score":0.74071336,"about_ca_system_score_codex":0.0008820454,"about_ca_system_score_gemma":0.0011838803,"threshold_uncertainty_score":0.6447576},"labels":[],"label_agreement":null},{"id":"W4393001199","doi":"10.3390/pediatric16010020","title":"Two versus Three Infusion Regimens of N-Acetylcysteine for Acetaminophen Overdose","year":2024,"lang":"en","type":"article","venue":"Pediatric Reports","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Montreal Children's Hospital; McGill University Health Centre; University of Saskatchewan","funders":"Taif University; McGill University","keywords":"Medicine; Regimen; Acetaminophen; Adverse effect; Liver transplantation; Acetylcysteine; acetaminophen overdose; Toxicity; Antidote; Transplantation; Anesthesia; Internal medicine","score_opus":0.1416547780766008,"score_gpt":0.44349392436341034,"score_spread":0.3018391462868095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393001199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9733635,0.0028802494,0.0011277585,0.00030281564,0.01044727,0.0012944858,0.000046295132,0.00026013106,0.010277499],"genre_scores_gemma":[0.99538237,0.00043794842,0.00050662673,0.000080562306,0.0019238042,0.00019195752,0.00004374229,0.00003860605,0.0013943862],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981424,0.00011813976,0.00066603185,0.00046316945,0.00023426743,0.00037595772],"domain_scores_gemma":[0.99848735,0.00059773464,0.00031804095,0.00031483994,0.000130043,0.00015201322],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013303356,0.00022858677,0.00032366047,0.00024071596,0.00018266602,0.000025895131,0.00011554377,0.00036103264,0.00035617355],"category_scores_gemma":[0.00028775865,0.00021875811,0.00021720704,0.00049443485,0.00006571586,0.00018567072,0.0000919379,0.0005354495,0.000039323306],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009864589,0.0024532138,0.112354405,0.009926624,0.002526361,0.0043981695,0.0057367557,0.0065074116,0.4069187,0.021218356,0.08721944,0.33087596],"study_design_scores_gemma":[0.008739931,0.0018925705,0.0028797213,0.00009700314,0.0027255607,0.00064190937,0.00011424965,0.014840303,0.15545729,0.01341417,0.7978435,0.0013537558],"about_ca_topic_score_codex":0.00009359782,"about_ca_topic_score_gemma":0.000030508954,"teacher_disagreement_score":0.7106241,"about_ca_system_score_codex":0.00011678476,"about_ca_system_score_gemma":0.00020285007,"threshold_uncertainty_score":0.8920697},"labels":[],"label_agreement":null},{"id":"W4393017336","doi":"10.7202/1108442ar","title":"La prise en charge des surdoses d’acétaminophène à l’urgence : sujet étonnamment complexe !","year":2023,"lang":"fr","type":"article","venue":"Soins d’urgence La revue de l’Association des infirmières et infirmiers d’urgence du Québec","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean","funders":"","keywords":"Physics; Philosophy","score_opus":0.09999474701879148,"score_gpt":0.3878555421486971,"score_spread":0.28786079512990564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393017336","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.922186,0.0037396913,0.0011448405,0.053190935,0.007150705,0.002230902,0.0009420583,0.0012415575,0.008173315],"genre_scores_gemma":[0.9711719,0.007307549,0.0004322058,0.002315782,0.00145801,0.0009001767,0.00025688647,0.0002265841,0.015930887],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.98359054,0.007828488,0.0022397435,0.0016326158,0.0010874048,0.0036212115],"domain_scores_gemma":[0.98625386,0.008684786,0.0016930352,0.00093659596,0.00086828804,0.001563412],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"category_scores_codex":[0.013898697,0.0014213574,0.0014962906,0.0009798192,0.0025489647,0.00048359288,0.0015131132,0.0030203967,0.0063477145],"category_scores_gemma":[0.005161612,0.0017545621,0.00093430706,0.003475988,0.002233484,0.0018800998,0.00073996966,0.0042727157,0.0035934204],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007360833,0.0025307294,0.62091386,0.003392002,0.0021384358,0.001296952,0.054575615,0.017594684,0.01760207,0.1690866,0.04197653,0.06815644],"study_design_scores_gemma":[0.0014457066,0.00027269791,0.031164993,0.00071793864,0.00055593165,0.0003344765,0.0020574236,0.019630868,0.008078893,0.003580957,0.93044066,0.0017194265],"about_ca_topic_score_codex":0.06900414,"about_ca_topic_score_gemma":0.05481575,"teacher_disagreement_score":0.88846415,"about_ca_system_score_codex":0.0062017348,"about_ca_system_score_gemma":0.0038293598,"threshold_uncertainty_score":0.9998537},"labels":[],"label_agreement":null},{"id":"W4393147481","doi":"10.1080/15563650.2024.2328351","title":"Assessing the impact of a new medical toxicology service on the treatment of paracetamol overdose at a large tertiary care hospital","year":2024,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Medicine; Retrospective cohort study; Emergency medicine; Drug overdose; Generalizability theory; Clinical toxicology; Medical emergency; Incidence (geometry); Intensive care medicine; Toxicology; Poison control; Surgery; Psychology","score_opus":0.2137684179537592,"score_gpt":0.5504193046001377,"score_spread":0.33665088664637843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393147481","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9775065,0.0017836178,0.00006644962,0.0135549875,0.003623504,0.0014286436,0.00011719798,0.00009771984,0.0018213806],"genre_scores_gemma":[0.9931985,0.00095109124,0.000030751147,0.004177669,0.0010641243,0.00016219029,0.000029572082,0.000041369905,0.00034470935],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9941344,0.002986222,0.0012251526,0.00063301844,0.00031743836,0.00070376764],"domain_scores_gemma":[0.9896578,0.008837285,0.00039533194,0.0005765645,0.00013722261,0.0003957705],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0021374216,0.0004133391,0.0008301485,0.00011982122,0.00037360357,0.000033825163,0.00062513433,0.0016294958,0.0038175094],"category_scores_gemma":[0.0009243395,0.0002260364,0.0008550295,0.00047716303,0.0006821567,0.000123258,0.0002240422,0.0016701521,0.00024850958],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033685167,0.022710351,0.2424362,0.0007402237,0.008297872,0.0011380721,0.032185387,0.0013980821,0.025033973,0.009146327,0.037840508,0.6157045],"study_design_scores_gemma":[0.014539199,0.026355712,0.46428004,0.00048427779,0.0020172987,0.00040210667,0.0028395231,0.04056878,0.06572506,0.0045817993,0.3767724,0.001433817],"about_ca_topic_score_codex":0.00015719462,"about_ca_topic_score_gemma":0.00027030552,"teacher_disagreement_score":0.6142707,"about_ca_system_score_codex":0.00045748282,"about_ca_system_score_gemma":0.0011352105,"threshold_uncertainty_score":0.9996666},"labels":[],"label_agreement":null},{"id":"W4394260219","doi":"10.6084/m9.figshare.21353324","title":"Naringin regulates mitochondrial dynamics to protect against acetaminophen-induced hepatotoxicity by activating the AMPK/Nrf2 signaling pathway in vitro","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; University of Toronto","funders":"","keywords":"Naringin; AMPK; In vitro; Chemistry; Acetaminophen; Pharmacology; Signal transduction; Cell biology; Biology; Biochemistry; Phosphorylation; Protein kinase A","score_opus":0.09697589331176411,"score_gpt":0.36021624489494275,"score_spread":0.26324035158317866,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394260219","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.02922894,0.00010414973,0.0000019479544,0.00034054488,0.0017795173,0.0055531743,0.9626261,0.00020596797,0.00015967544],"genre_scores_gemma":[0.026382044,0.000010290559,0.000030941224,0.0019295039,0.00083363085,0.0073711574,0.96312,0.00012170455,0.0002007485],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99330133,0.0022389805,0.0010566809,0.0013407216,0.00073670107,0.0013255756],"domain_scores_gemma":[0.9964125,0.0012384561,0.00087011344,0.00094446726,0.00015021964,0.00038420997],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00097426673,0.001031156,0.00096863066,0.00049014366,0.0015207609,0.00021253318,0.0017841565,0.0018649439,0.100812055],"category_scores_gemma":[0.002596349,0.0009903883,0.0003664097,0.0012549305,0.000038728856,0.0002649608,0.0011575861,0.00796204,0.0006034341],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00056501874,0.00029810463,0.000002471221,0.00046887645,0.0001522423,0.0000989467,0.0003115985,0.0010590096,0.1943363,7.978128e-7,0.7944028,0.008303843],"study_design_scores_gemma":[0.0008389458,0.00013442579,0.000004267915,0.00044505234,0.000029255501,0.0000155097,0.000107787426,0.0014931469,0.32020873,0.000021221445,0.6758771,0.00082456484],"about_ca_topic_score_codex":0.00044014314,"about_ca_topic_score_gemma":0.00047017535,"teacher_disagreement_score":0.12587243,"about_ca_system_score_codex":0.00157552,"about_ca_system_score_gemma":0.0004921129,"threshold_uncertainty_score":0.9997791},"labels":[],"label_agreement":null},{"id":"W4396502708","doi":"10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a7348","title":"Poutine-induced Hypoxemia: A Case Report","year":2024,"lang":"en","type":"article","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke","funders":"","keywords":"Hypoxemia; Computer science; Medicine; Cardiology","score_opus":0.2077502302446147,"score_gpt":0.47918959881116674,"score_spread":0.27143936856655204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396502708","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84571725,0.00028031817,0.0006646842,0.002526769,0.005139889,0.00052738003,0.000018778219,0.0010049372,0.14411998],"genre_scores_gemma":[0.9835688,0.000028981198,0.0002036504,0.0013780197,0.0008216873,0.00010503633,0.000015644824,0.000036408197,0.013841788],"study_design_codex":"case_report","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981776,0.0002779274,0.00043237655,0.00050578435,0.00014834003,0.00045796865],"domain_scores_gemma":[0.9990409,0.00030538885,0.000060833525,0.0002674722,0.00006990376,0.0002554892],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0012711644,0.00024215587,0.00021767277,0.000191596,0.00035314073,0.00007625036,0.00012651639,0.0006247808,0.003143734],"category_scores_gemma":[0.00014064787,0.0002172445,0.00015944608,0.00045296983,0.0000619602,0.00022106794,0.000074373675,0.0015565072,0.0016133913],"study_design_candidate":"case_report","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014046697,0.00032517494,0.0006532297,0.00028129088,0.00046726572,0.5658831,0.0014372831,0.000060364036,0.22149272,0.014619023,0.028129816,0.16651024],"study_design_scores_gemma":[0.0005819457,0.00011936921,0.00006330651,0.00003140815,0.00018142204,0.23991667,0.00026048542,0.009170434,0.2398798,0.0020665433,0.50725365,0.00047499937],"about_ca_topic_score_codex":0.000298181,"about_ca_topic_score_gemma":0.00013033212,"teacher_disagreement_score":0.4791238,"about_ca_system_score_codex":0.00012749791,"about_ca_system_score_gemma":0.00017192372,"threshold_uncertainty_score":0.999164},"labels":[],"label_agreement":null},{"id":"W4396505291","doi":"10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a1122","title":"Sepsis Patients With Hyperinflammatory and Hypoinflammatory Phenotypes Respond Differently to Polymyxin B Compared to Sham in a Secondary Analysis of Euphrates","year":2024,"lang":"en","type":"article","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Iridian Spectral Technologies (Canada)","funders":"","keywords":"Sepsis; Polymyxin B; Phenotype; Medicine; Polymyxin; Internal medicine; Immunology; Biology; Microbiology; Antibiotics; Genetics; Gene","score_opus":0.04380257704050659,"score_gpt":0.36147656368091086,"score_spread":0.31767398664040425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396505291","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953433,0.00019356592,0.00008901564,0.00037278226,0.0002527218,0.00079013576,0.00015286428,0.00010894953,0.0026966503],"genre_scores_gemma":[0.99830115,0.000011481632,0.00023046299,0.0007633352,0.000039420822,0.00011446434,0.000031582913,0.000026717229,0.000481411],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981876,0.0003228108,0.00046564636,0.00047486732,0.0001938889,0.0003551599],"domain_scores_gemma":[0.99900967,0.00035759123,0.00006399583,0.00019879895,0.00008249235,0.00028747463],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00048458108,0.00026474483,0.00051659433,0.001325015,0.00010471271,0.000045389526,0.00015543666,0.00021970794,0.00092306413],"category_scores_gemma":[0.00004106875,0.00022694597,0.00008623706,0.0015039,0.00008253846,0.00017553703,0.000112847585,0.0004960863,0.00005706128],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005556268,0.00065468805,0.79614544,0.0006127478,0.0035957661,0.00007817365,0.014235149,0.0026293127,0.09704683,0.001452825,0.0008306256,0.07716217],"study_design_scores_gemma":[0.0015059308,0.00031223553,0.9281831,0.00009422827,0.0006838718,0.0000017896067,0.0004594172,0.0043924083,0.052337036,0.000095473784,0.011449389,0.0004851319],"about_ca_topic_score_codex":0.00015122791,"about_ca_topic_score_gemma":0.0016212562,"teacher_disagreement_score":0.13203764,"about_ca_system_score_codex":0.000102175996,"about_ca_system_score_gemma":0.00009964548,"threshold_uncertainty_score":0.9999902},"labels":[],"label_agreement":null},{"id":"W4399900296","doi":"10.1002/ped4.12438","title":"International outbreak of acute pediatric hepatitis: Was acetaminophen the missing link?","year":2024,"lang":"en","type":"article","venue":"Pediatric Investigation","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Outbreak; Medicine; Acetaminophen; Epidemiology; Pediatrics; Internal medicine; Virology; Pharmacology","score_opus":0.08205436208101297,"score_gpt":0.37900741320527015,"score_spread":0.2969530511242572,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399900296","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9701402,0.0019000568,0.0010337974,0.012514818,0.0077280095,0.00063201337,0.00014875777,0.00027929177,0.0056230584],"genre_scores_gemma":[0.9884713,0.0039601545,0.0004862507,0.0008791588,0.005309608,0.00008368348,0.00010753978,0.00003056514,0.0006717318],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981278,0.0003940951,0.00052882737,0.00033274826,0.00032876516,0.00028771654],"domain_scores_gemma":[0.99882096,0.00047423792,0.00022892962,0.0001829845,0.0001526927,0.00014017343],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011238123,0.00020992449,0.00018783861,0.00033311162,0.0003067845,0.000084632,0.00033389928,0.00037843396,0.00033738336],"category_scores_gemma":[0.00015879923,0.00017429233,0.00013625152,0.00078041386,0.00013552594,0.00037098175,0.00009034422,0.0009673238,0.00023874],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024450873,0.0002956594,0.5921667,0.0015863639,0.0012646848,0.00012937267,0.014995575,0.0017123927,0.052164946,0.014608126,0.028935522,0.29189616],"study_design_scores_gemma":[0.004143924,0.00066849164,0.1819608,0.00016252196,0.01018956,0.00030928594,0.00030681922,0.21301349,0.2022403,0.08526711,0.29918712,0.0025505642],"about_ca_topic_score_codex":0.00011296123,"about_ca_topic_score_gemma":0.0000068379477,"teacher_disagreement_score":0.4102059,"about_ca_system_score_codex":0.00012720434,"about_ca_system_score_gemma":0.00024795966,"threshold_uncertainty_score":0.7107435},"labels":[],"label_agreement":null},{"id":"W4400664213","doi":"10.1503/cmaj.150837-l","title":"Acetaminophen as a cause of “non-acetaminophen-related acute liver failure”","year":2024,"lang":"en","type":"letter","venue":"Canadian Medical Association Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chills; Acetaminophen; Medicine; Anorexia; Abdominal pain; Liver failure; Internal medicine; Anesthesia","score_opus":0.041717863252600546,"score_gpt":0.3516561190360686,"score_spread":0.309938255783468,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400664213","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04932401,0.0010515443,0.00002357553,0.92185515,0.014104937,0.0008372895,0.0006993249,0.00010798555,0.011996191],"genre_scores_gemma":[0.05853184,0.0018866727,0.00007236005,0.89156187,0.015227988,0.000088494075,0.00033982337,0.00017406816,0.032116897],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99379635,0.0014254918,0.0012656013,0.0005117004,0.0017449709,0.001255878],"domain_scores_gemma":[0.9958904,0.0006031517,0.000951766,0.00024663532,0.0006091905,0.0016988509],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0031776344,0.0005513445,0.0008838268,0.0008223805,0.00053266244,0.00014539403,0.000774494,0.008793284,0.021775424],"category_scores_gemma":[0.0009248188,0.0005476117,0.00051990186,0.00064033293,0.00020244023,0.00022120915,0.00008074581,0.021498758,0.00387854],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018939645,0.00003747799,0.0004031863,0.00015177412,0.0031931933,0.0126643125,0.0010455617,0.000007000654,0.00021549314,0.00005368917,0.9699626,0.012246791],"study_design_scores_gemma":[0.0011487147,0.0001425174,0.00021193227,0.0002462967,0.0012277426,0.0023142372,0.00008051468,0.0006444983,0.00058585266,0.00057129166,0.9923092,0.0005171869],"about_ca_topic_score_codex":0.002995488,"about_ca_topic_score_gemma":0.0057738046,"teacher_disagreement_score":0.030293284,"about_ca_system_score_codex":0.0025548427,"about_ca_system_score_gemma":0.0063404227,"threshold_uncertainty_score":0.99969757},"labels":[],"label_agreement":null},{"id":"W4400744959","doi":"10.21203/rs.3.rs-4618612/v1","title":"Cholinergic agonist Carbachol improves N-acetylcysteine treatment on Paracetamol-induced experimental hepatotoxicity in mice","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SAIT Polytechnic","funders":"","keywords":"Carbachol; Agonist; Acetylcysteine; Cholinergic; Pharmacology; Medicine; Chemistry; Anesthesia; Endocrinology; Internal medicine; Receptor; Biochemistry; Antioxidant","score_opus":0.2763933630525264,"score_gpt":0.5280480067095252,"score_spread":0.25165464365699886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400744959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97547626,0.0030817296,0.0000019012211,0.0016557984,0.003227913,0.0059434623,0.0005238781,0.00037486592,0.009714187],"genre_scores_gemma":[0.98886055,0.00094195706,0.00004179723,0.00027020296,0.0015250815,0.004863547,0.00029699376,0.00017129084,0.003028604],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99021953,0.003853937,0.0010092575,0.0020314753,0.0010906252,0.0017951663],"domain_scores_gemma":[0.99707574,0.0007545391,0.0002355076,0.0009858278,0.00026381834,0.0006845461],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0033386336,0.0010543918,0.0011165699,0.0013006539,0.0007187489,0.00032457887,0.00084171694,0.0024836694,0.00038619107],"category_scores_gemma":[0.00023427213,0.000985795,0.0005718658,0.00096046075,0.00035881964,0.0001229055,0.0014100736,0.010787334,0.0011670856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028702018,0.0060339067,0.0011862734,0.0022716408,0.00057591405,0.0014099459,0.006049343,0.0042621843,0.9554773,0.0008899095,0.0011584881,0.017814903],"study_design_scores_gemma":[0.0041904547,0.003036437,0.00074242125,0.0008735347,0.00010480341,0.000043873468,0.0010357668,0.020017253,0.9479194,0.0013944578,0.019464469,0.001177121],"about_ca_topic_score_codex":0.0040963213,"about_ca_topic_score_gemma":0.00084895495,"teacher_disagreement_score":0.01830598,"about_ca_system_score_codex":0.0040599676,"about_ca_system_score_gemma":0.0010750848,"threshold_uncertainty_score":0.99976325},"labels":[],"label_agreement":null},{"id":"W4400764945","doi":"10.3390/cimb46070448","title":"Phytotherapy-Induced Hepatocytotoxicity: A Case Report","year":2024,"lang":"en","type":"review","venue":"Current Issues in Molecular Biology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemokine; Medicine; Proinflammatory cytokine; Toxicity; Pharmacology; Immune system; Immunology; Inflammation; Internal medicine","score_opus":0.2701614282187833,"score_gpt":0.5653254490017865,"score_spread":0.2951640207830032,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400764945","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0019279479,0.98326075,0.00038738866,0.00011661916,0.009956877,0.0030133324,0.00019320355,0.00031692986,0.00082696724],"genre_scores_gemma":[0.0020600408,0.9941668,0.000112011025,0.00018364326,0.0010398785,0.0015602675,0.0004348651,0.00017594689,0.00026657662],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99247503,0.003015256,0.0016626214,0.0016109766,0.000181399,0.0010547104],"domain_scores_gemma":[0.9978894,0.00025335787,0.00060618576,0.000867336,0.00009079292,0.0002929022],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0018408793,0.0011663176,0.002600263,0.0010242527,0.00019643187,0.00006480372,0.00062482816,0.0027612427,0.00031131261],"category_scores_gemma":[0.00024549922,0.001029641,0.0009859616,0.0011326867,0.00026364374,0.00007711777,0.00036041925,0.0053724544,0.0008918899],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025608522,0.0003558397,0.0000132038385,0.0084858425,0.0005141646,0.07766157,0.00024185728,0.0000017691406,0.0005388228,0.0017851164,0.00047850327,0.9098977],"study_design_scores_gemma":[0.00040935926,0.00015390362,1.00133924e-7,0.0029335252,0.0010426186,0.03222632,0.000013386554,0.000098779965,0.00114825,0.0023100404,0.95870984,0.00095389935],"about_ca_topic_score_codex":0.00010376044,"about_ca_topic_score_gemma":0.000077174685,"teacher_disagreement_score":0.95823133,"about_ca_system_score_codex":0.00049814786,"about_ca_system_score_gemma":0.00047129884,"threshold_uncertainty_score":0.99988604},"labels":[],"label_agreement":null},{"id":"W4401231822","doi":"10.1136/annrheumdis-2024-eular.25","title":"AB0472 EFFICACY OF GUSELKUMAB IN BIONAIVE PSORIATIC ARTHRITIS PATIENTS WITH SEVERE DISEASE ACTIVITY: POST-HOC ANALYSIS OF A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY","year":2024,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Psoriatic arthritis; Medicine; Placebo; Double blind; Post-hoc analysis; Arthritis; Internal medicine; Dermatology; Alternative medicine; Pathology","score_opus":0.08820157614001951,"score_gpt":0.42176197818181704,"score_spread":0.33356040204179754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401231822","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99017215,0.001822763,0.00003402821,0.00041888075,0.0003452559,0.00622853,0.0008747029,0.00003983906,0.00006383634],"genre_scores_gemma":[0.9986425,0.00052396033,0.0000074253117,0.00008491245,0.000019693254,0.0005970357,0.00005951668,0.000025570518,0.00003940666],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9956336,0.0020272688,0.0010846166,0.0003835419,0.0005555514,0.000315416],"domain_scores_gemma":[0.9953325,0.0028957499,0.00076476234,0.00046082083,0.0003335001,0.00021271536],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014129801,0.00033842924,0.0017470117,0.00075605384,0.00012244386,0.000029494551,0.00035557337,0.00012775608,0.0003182574],"category_scores_gemma":[0.0008135264,0.00022474308,0.0008975837,0.0015130272,0.00032607443,0.00026563086,0.00010029492,0.0003587728,0.000006680477],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.91054827,0.014005066,0.0041641747,0.0007054379,0.014503003,0.000011904253,0.0027667321,0.005798344,0.000040728657,0.00018654854,0.000046003024,0.04722381],"study_design_scores_gemma":[0.93999505,0.0014125956,0.017333923,0.001239327,0.01623075,8.801869e-7,0.00047240112,0.021090057,0.0010203132,0.0007660587,0.000018249646,0.00042036557],"about_ca_topic_score_codex":0.00023064084,"about_ca_topic_score_gemma":0.00014077743,"teacher_disagreement_score":0.046803445,"about_ca_system_score_codex":0.00003697015,"about_ca_system_score_gemma":0.00030756256,"threshold_uncertainty_score":0.91647565},"labels":[],"label_agreement":null},{"id":"W4401388801","doi":"10.1111/apt.18201","title":"Editorial: The future of managing drug induced liver injury","year":2024,"lang":"en","type":"editorial","venue":"Alimentary Pharmacology & Therapeutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. John’s Health Sciences Centre","funders":"","keywords":"Medicine; Drug; Liver injury; MEDLINE; Intensive care medicine; Pharmacology; Law","score_opus":0.05222711963505704,"score_gpt":0.40435892234955617,"score_spread":0.3521318027144991,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401388801","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007254688,0.011079129,0.0000040534374,0.005333477,0.97218263,0.0019359213,0.0010545838,0.00033013677,0.0008253607],"genre_scores_gemma":[0.00904879,0.023483982,0.000028349084,0.008696623,0.9562145,0.00040461836,0.00046047376,0.00023850691,0.0014241751],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9927833,0.0026399153,0.0012368718,0.0011077058,0.0010961001,0.0011360869],"domain_scores_gemma":[0.9955609,0.0022131456,0.00082941813,0.0006761576,0.0004540489,0.0002663586],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0027709054,0.001127188,0.0010754194,0.00047079314,0.000774758,0.000082599625,0.0017257163,0.0035386109,0.0013453424],"category_scores_gemma":[0.000002640489,0.0009327102,0.0005853443,0.00073681487,0.0006542729,0.0002760238,0.0006456619,0.010655983,0.0005303084],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012439671,0.00046054245,0.00001628832,0.00045416638,0.012678299,0.000054344513,0.0019423038,0.000026190935,0.039893754,0.000074547745,0.9300879,0.013067683],"study_design_scores_gemma":[0.0014198789,0.00035275836,0.0000022016623,0.00008045572,0.015921488,0.000009268269,0.00035715746,0.00029588828,0.06350272,0.00090894836,0.91637725,0.00077197875],"about_ca_topic_score_codex":0.00031382588,"about_ca_topic_score_gemma":0.00011027496,"teacher_disagreement_score":0.023608968,"about_ca_system_score_codex":0.0005547327,"about_ca_system_score_gemma":0.0007725622,"threshold_uncertainty_score":0.99956757},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"high"},{"model":"gpt","categories":[],"domain":null,"study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"high"}],"label_agreement":"agree"},{"id":"W4401873018","doi":"10.1016/j.biopha.2024.117353","title":"Retraction notice to 'Deaths induced by compassionate use of hydroxychloroquine during the first COVID-19 wave: an estimate' [Biomedicine &amp; Pharmacotherapy, Volume 171 (2024) 116055]","year":2024,"lang":"en","type":"retraction","venue":"Biomedicine & Pharmacotherapy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":true,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec","funders":"","keywords":"Hydroxychloroquine; Biomedicine; Notice; Coronavirus disease 2019 (COVID-19); Pharmacotherapy; Medicine; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); 2019-20 coronavirus outbreak; Compassionate Use; Intensive care medicine; Virology; Internal medicine; Political science; Bioinformatics","score_opus":0.21888278484983503,"score_gpt":0.4854300297357387,"score_spread":0.26654724488590364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401873018","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6973278,0.022236463,0.0023712942,0.103736855,0.14745004,0.014601634,0.008150492,0.0025810362,0.0015443881],"genre_scores_gemma":[0.5806342,0.11515437,0.0009206455,0.08905672,0.057079054,0.0035877605,0.008787917,0.0021871135,0.14259227],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9905997,0.0015466678,0.0023737426,0.0020415362,0.0018581466,0.0015801893],"domain_scores_gemma":[0.9937998,0.0010730488,0.0015085584,0.0011742063,0.00051363284,0.0019307738],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.0037472968,0.0017913232,0.0019620245,0.0021600944,0.0014544269,0.00019035154,0.0010207772,0.0029231184,0.014033072],"category_scores_gemma":[0.00022610123,0.0014253616,0.00055243116,0.0032028907,0.0007309252,0.0008756575,0.0001900402,0.0076167607,0.0006809245],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033538796,0.0010602707,0.00012679934,0.0017638908,0.0012218258,0.00012561838,0.0017250814,0.0002722418,0.5300943,0.0000074395225,0.4279534,0.032295223],"study_design_scores_gemma":[0.0062443195,0.0011130552,0.00029668695,0.00054551114,0.001305436,0.0003954901,0.00010667603,0.0062481663,0.058895912,0.000034665645,0.9235194,0.0012947334],"about_ca_topic_score_codex":0.0026360757,"about_ca_topic_score_gemma":0.00027618982,"teacher_disagreement_score":0.49556595,"about_ca_system_score_codex":0.0019997724,"about_ca_system_score_gemma":0.0007872433,"threshold_uncertainty_score":0.99984556},"labels":[],"label_agreement":null},{"id":"W4403507195","doi":"10.5539/jsd.v17n6p95","title":"Quinclorac (QCR) Herbicide Induces Hepatotoxicity, Cytotoxicity, and Oxidative Stress in Zebrafish Liver (ZF-L) Cells: An Evaluation of a Seized Formulation","year":2024,"lang":"en","type":"article","venue":"Journal of Sustainable Development","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Oxidative stress; Cytotoxicity; Zebrafish; Chemistry; Pharmacology; Biochemistry; Biology; In vitro; Gene","score_opus":0.1019956015885264,"score_gpt":0.39686154489162445,"score_spread":0.29486594330309807,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403507195","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964066,0.0009852385,0.00039343382,0.00016213598,0.00043365167,0.0011993241,0.000010186352,0.000032236334,0.00037717813],"genre_scores_gemma":[0.9984908,0.00023101197,0.0007976433,0.000116838615,0.00014884149,0.00006902766,0.0000126686955,0.00002905541,0.00010407289],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99622273,0.0011400335,0.0011038061,0.0003166767,0.00074443413,0.0004723435],"domain_scores_gemma":[0.99776304,0.0003230433,0.000565153,0.00011856561,0.0010150606,0.00021515189],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.007377874,0.0002849413,0.00048584363,0.00095602026,0.00023481231,0.00010017629,0.00022916072,0.00042159331,0.00017583888],"category_scores_gemma":[0.00022084356,0.00026913825,0.000088475565,0.0007073659,0.00008885388,0.0014443664,0.00014561557,0.0010704112,0.000005530651],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018086825,0.0022566465,0.012108763,0.0025121365,0.0008485142,0.0010497906,0.06086398,0.0072462694,0.8446561,0.0026583758,0.00029459363,0.063696146],"study_design_scores_gemma":[0.0023297002,0.00041437408,0.014182335,0.00036662442,0.00019706071,0.0000850325,0.009010095,0.01941938,0.94850856,0.0032752594,0.0018609072,0.00035069897],"about_ca_topic_score_codex":0.00016449831,"about_ca_topic_score_gemma":0.00021023792,"teacher_disagreement_score":0.10385243,"about_ca_system_score_codex":0.0010719793,"about_ca_system_score_gemma":0.0013125965,"threshold_uncertainty_score":0.9999761},"labels":[],"label_agreement":null},{"id":"W4403904791","doi":"10.1016/s1473-3099(24)00598-x","title":"Predictable excess hepatotoxicity in the SimpliciTB trial","year":2024,"lang":"en","type":"letter","venue":"The Lancet Infectious Diseases","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Internal medicine","score_opus":0.15580663763189814,"score_gpt":0.42608931410672696,"score_spread":0.27028267647482884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403904791","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.308915,0.003328705,0.000040330855,0.61394787,0.015473577,0.008402338,0.0026072364,0.0016318904,0.045653068],"genre_scores_gemma":[0.427494,0.0006549092,8.1534904e-7,0.54308265,0.025246613,0.002162833,0.00027327528,0.000081144746,0.0010037787],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99368614,0.0033028536,0.0006422568,0.00070972886,0.0005411716,0.0011178241],"domain_scores_gemma":[0.9965346,0.0020772847,0.00030058838,0.00090807263,0.00007223535,0.00010725372],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0018661282,0.000652553,0.00088979106,0.00025355848,0.00075181527,0.00030180573,0.0012868295,0.0015661878,0.0006267844],"category_scores_gemma":[0.0003214667,0.00040341864,0.00043206115,0.0008059908,0.00038043127,0.0001798706,0.00021653953,0.009241401,0.00066115597],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002308055,0.00040160402,0.00317488,0.00060162164,0.00034710314,0.00042359912,0.00067847,0.00021821693,0.00003751186,0.0002937903,0.98930216,0.0022130073],"study_design_scores_gemma":[0.008996157,0.00027835282,0.00050025695,0.00010558393,0.00072301296,0.000094588366,0.000042943924,0.0005500611,0.00014482648,0.015385727,0.9726673,0.00051118754],"about_ca_topic_score_codex":0.0004931184,"about_ca_topic_score_gemma":0.0002632691,"teacher_disagreement_score":0.11857899,"about_ca_system_score_codex":0.00028286703,"about_ca_system_score_gemma":0.0002724646,"threshold_uncertainty_score":0.99984175},"labels":[],"label_agreement":null},{"id":"W4404120946","doi":"10.24908/qap.v1i2.17352","title":"Thapsigargin: An Unlikely Drug in the Battle Against Viral Pandemics","year":2024,"lang":"en","type":"article","venue":"Qapsule Queen s Undergraduate Health Sciences Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Battle; Pandemic; Drug; Virology; Thapsigargin; Coronavirus disease 2019 (COVID-19); Medicine; Pharmacology; History; Ancient history; Internal medicine; Infectious disease (medical specialty); Disease","score_opus":0.1460836602190165,"score_gpt":0.46686531951347615,"score_spread":0.3207816592944597,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404120946","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8211254,0.0029812115,0.0016685339,0.1527698,0.011495368,0.00090853084,0.00003487294,0.00023832559,0.00877795],"genre_scores_gemma":[0.98332417,0.004346857,0.00040531906,0.010561002,0.0009826164,0.00003310094,0.000009851711,0.000023657472,0.0003134433],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99430996,0.0027268531,0.00077077415,0.00051329104,0.00063296413,0.0010461437],"domain_scores_gemma":[0.9982424,0.0008014903,0.0002486694,0.0001991662,0.000064939624,0.00044336557],"candidate_categories":["sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.01143021,0.00029336332,0.00031471666,0.000459015,0.0020458393,0.00049830176,0.00087566295,0.00023398873,0.000057204154],"category_scores_gemma":[0.000103198065,0.00020389659,0.0001411142,0.001219982,0.0005288128,0.0009870185,0.000059284215,0.0034289546,0.000094517905],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043208708,0.0019502991,0.027376933,0.000846775,0.0002766927,0.0011154106,0.049695827,0.02485802,0.0046936916,0.10755079,0.08954586,0.6916576],"study_design_scores_gemma":[0.002746983,0.0018892487,0.005155674,0.0005816271,0.00008940266,0.0018238992,0.0082413,0.11887266,0.0030551567,0.15256622,0.7036567,0.0013211615],"about_ca_topic_score_codex":0.00040599966,"about_ca_topic_score_gemma":0.00047219393,"teacher_disagreement_score":0.69033647,"about_ca_system_score_codex":0.00038387964,"about_ca_system_score_gemma":0.0013799618,"threshold_uncertainty_score":0.99925333},"labels":[],"label_agreement":null},{"id":"W4404319493","doi":"10.3390/curroncol31110525","title":"Risk Factors of Immune-Mediated Hepatotoxicity Induced by Immune Checkpoint Inhibitors in Cancer Patients: A Systematic Review and Meta-Analysis","year":2024,"lang":"en","type":"review","venue":"Current Oncology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Meta-analysis; Immune system; Cancer; Bioinformatics; Oncology; Pharmacology; Immunology; Internal medicine; Biology","score_opus":0.3475820585585179,"score_gpt":0.519175842810672,"score_spread":0.17159378425215405,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404319493","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0051391586,0.9810129,0.0000030435024,0.00007710471,0.001909376,0.008298671,0.003419825,0.00008716647,0.000052789776],"genre_scores_gemma":[0.009876868,0.9845742,0.000003225327,0.00007630411,0.00005391185,0.0044277515,0.00085321924,0.00008373347,0.000050770137],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.98557764,0.00734617,0.0048506293,0.0011171743,0.0003782701,0.0007301091],"domain_scores_gemma":[0.993224,0.0014551374,0.004147309,0.0005945661,0.0002741496,0.0003048281],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0040641306,0.0012449767,0.013743649,0.0012647038,0.00017295979,0.000027749104,0.0006132372,0.0019604336,0.00059312355],"category_scores_gemma":[0.00113996,0.00088554574,0.0039218836,0.0029117952,0.0002642213,0.00015446109,0.00039466802,0.0049807234,0.000073210904],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022064158,0.0019339966,0.00028864635,0.8555872,0.12472087,0.00000701496,0.0006061527,0.0000018483303,0.000033168937,0.000008434325,0.00026768754,0.016522946],"study_design_scores_gemma":[0.00056559854,0.00028521154,0.00001902804,0.017892297,0.8609029,0.0000040563605,0.000035701705,0.00006178617,0.00017401789,0.000019619549,0.11921377,0.00082604017],"about_ca_topic_score_codex":0.00089355797,"about_ca_topic_score_gemma":0.0002672863,"teacher_disagreement_score":0.8376949,"about_ca_system_score_codex":0.0011329302,"about_ca_system_score_gemma":0.00049940986,"threshold_uncertainty_score":0.99935955},"labels":[],"label_agreement":null},{"id":"W4404716728","doi":"10.51731/cjht.2024.1033","title":"Remdesivir (Veklury)","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Virology; Medicine","score_opus":0.1986343850936048,"score_gpt":0.45803941880608745,"score_spread":0.2594050337124827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404716728","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3507589,0.40365958,0.0029779905,0.20713618,0.020652816,0.0011723328,0.0001372988,0.0015286087,0.011976273],"genre_scores_gemma":[0.9968453,0.0013484866,0.00022023743,0.0011813248,0.00006829172,0.000010249444,0.0000016684377,0.000019354342,0.0003050726],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99835074,0.00025314305,0.00055746746,0.00016487596,0.00010849647,0.00056525273],"domain_scores_gemma":[0.9992229,0.000167897,0.00019636088,0.00015027222,0.00010278513,0.00015978249],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019763731,0.00015249614,0.0002900319,0.0008986644,0.00044519434,0.00006352994,0.0003748627,0.0004834765,0.0002058416],"category_scores_gemma":[0.00037737912,0.00013595968,0.000112369555,0.0005551452,0.00025876658,0.00021544218,0.000018526976,0.0020304313,0.00012876294],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013346326,0.000013754131,0.0005714452,0.00017786346,0.00007305789,0.0003981355,0.0004565975,0.000045111763,0.0008016254,0.0070196236,0.017191937,0.9732375],"study_design_scores_gemma":[0.00018426706,0.00021892661,0.00038567215,0.00016411018,0.000020439744,0.0005260653,0.000612017,0.00016829392,0.008533652,0.012705623,0.9763454,0.00013549461],"about_ca_topic_score_codex":0.0012496882,"about_ca_topic_score_gemma":0.0017067564,"teacher_disagreement_score":0.97310203,"about_ca_system_score_codex":0.00052799727,"about_ca_system_score_gemma":0.0028014642,"threshold_uncertainty_score":0.88213265},"labels":[],"label_agreement":null},{"id":"W4404886780","doi":"10.1097/01.eem.0001095468.99599.b8","title":"Acetaminophen in Pregnancy is Probably Safe, but No One Really Knows for Sure","year":2024,"lang":"en","type":"article","venue":"Emergency Medicine News","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Pregnancy; Acetaminophen; Psychology; Obstetrics; Medicine; Pharmacology","score_opus":0.20750069518856762,"score_gpt":0.4530762943097798,"score_spread":0.24557559912121218,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404886780","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.32983762,0.045797046,0.0026772644,0.0393873,0.05927703,0.012947098,0.00051239145,0.0010874325,0.5084768],"genre_scores_gemma":[0.7660422,0.024513572,0.0010218472,0.00318777,0.009519824,0.0032498143,0.0003015746,0.00022865133,0.19193475],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99711084,0.00035528885,0.0009178238,0.00067398563,0.00027239107,0.0006696897],"domain_scores_gemma":[0.9988823,0.00024257855,0.00014130755,0.00030826902,0.00018062374,0.00024491962],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011011224,0.000366559,0.0005059472,0.0003071885,0.00020341657,0.000008186557,0.0003167397,0.00059582293,0.012205094],"category_scores_gemma":[0.0003750077,0.00032931851,0.00016238556,0.00067604077,0.00010844291,0.00022443625,0.000058935686,0.0012125572,0.0006999878],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010818437,0.0010617154,0.0066652475,0.004544487,0.000702824,0.00010126415,0.009294523,0.00008773337,0.19776268,0.009478411,0.48935717,0.2798621],"study_design_scores_gemma":[0.0023010804,0.0007908894,0.0012895323,0.0009231209,0.00026893034,0.000012583093,0.00015667552,0.0030544999,0.01422752,0.007048356,0.96944135,0.00048545253],"about_ca_topic_score_codex":0.00054253486,"about_ca_topic_score_gemma":0.00073692657,"teacher_disagreement_score":0.48008418,"about_ca_system_score_codex":0.0001412413,"about_ca_system_score_gemma":0.00019021804,"threshold_uncertainty_score":0.9999159},"labels":[],"label_agreement":null},{"id":"W4406451018","doi":"10.1016/s1283-0828(08)39383-1","title":"10.1016/s1283-0828(08)39383-1","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Philosophy","score_opus":0.05903417797473162,"score_gpt":0.3292903615746265,"score_spread":0.2702561835998949,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406451018","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011826991,0.00008323479,0.0000030870851,0.00088535575,0.000031703225,0.00064047804,0.00006193317,0.00034578706,0.9861214],"genre_scores_gemma":[0.0048546838,0.0000030354465,0.000065077424,0.0007223898,0.00052699464,0.00012212063,0.000031029776,0.000040498086,0.99363416],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981158,0.0003945873,0.0003209018,0.0004019664,0.00018205818,0.0005847336],"domain_scores_gemma":[0.99903804,0.00015903756,0.000062397776,0.0002892517,0.000065709704,0.0003855419],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0006349315,0.00027113332,0.00027708148,0.00013811787,0.00039402934,0.000037425267,0.0003284245,0.00045646945,0.99751353],"category_scores_gemma":[0.000056751895,0.00028612444,0.00012237822,0.00037569026,0.000089992776,0.00016635882,0.000058099526,0.00087151036,0.9952736],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005215658,0.00021096016,0.0000012509126,0.00001778669,0.00007352519,0.000019826499,0.00009493639,0.0004590923,0.0031256794,0.0000061783817,0.18930642,0.8061628],"study_design_scores_gemma":[0.00076963444,0.0002196489,0.000033616154,0.000012197663,0.00006408377,0.000033130298,0.0000023880946,0.0008425819,0.011854768,0.000074429605,0.98574626,0.00034724214],"about_ca_topic_score_codex":0.00003722736,"about_ca_topic_score_gemma":0.0000013587876,"teacher_disagreement_score":0.8058155,"about_ca_system_score_codex":0.000100999765,"about_ca_system_score_gemma":0.000062289524,"threshold_uncertainty_score":0.9999591},"labels":[],"label_agreement":null},{"id":"W4406469350","doi":"10.1111/liv.16239","title":"Development and Validation of a Novel Model to Discriminate Idiosyncratic Drug‐Induced Liver Injury and Autoimmune Hepatitis","year":2025,"lang":"en","type":"article","venue":"Liver International","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Sinai Hospital","funders":"National Key Research and Development Program of China","keywords":"Autoimmune hepatitis; Liver injury; Drug; Medicine; Hepatitis; Drug development; Immunology; Pharmacology","score_opus":0.11538580831534608,"score_gpt":0.3977545619953591,"score_spread":0.282368753680013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406469350","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887347,0.0000632557,0.0069668875,0.0006948804,0.00067431125,0.00037901677,0.00005295046,0.000032072694,0.002401931],"genre_scores_gemma":[0.9923429,0.00012216669,0.004850329,0.0007263615,0.00003483788,0.00007756356,0.000023075863,0.000008277622,0.0018144953],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990809,0.00007593466,0.00030815153,0.00024470352,0.00014507528,0.00014525464],"domain_scores_gemma":[0.9995407,0.00009151321,0.00009803525,0.00007992067,0.00012159179,0.000068250054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036688024,0.00014012863,0.00016148029,0.00023758342,0.00015953796,0.000027595295,0.00013838048,0.00013560269,0.000083941675],"category_scores_gemma":[0.00005937239,0.00014914753,0.000028997905,0.00011853372,0.00005619761,0.00018768151,0.00017756478,0.00026490923,0.000010669928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007009004,0.0008469913,0.010775642,0.0003921571,0.0006499803,0.0000123675,0.018657593,0.0016283736,0.69894654,0.046998065,0.0009101232,0.21948129],"study_design_scores_gemma":[0.0015156103,0.00006301364,0.037164032,0.00017379683,0.000108617656,0.000012457407,0.00016227466,0.2635438,0.68824196,0.0008422315,0.007849816,0.00032233575],"about_ca_topic_score_codex":0.0001775173,"about_ca_topic_score_gemma":0.000085274514,"teacher_disagreement_score":0.26191545,"about_ca_system_score_codex":0.00009854504,"about_ca_system_score_gemma":0.00009094692,"threshold_uncertainty_score":0.608206},"labels":[],"label_agreement":null},{"id":"W4406554903","doi":"10.1016/s1634-6939(18)78364-6","title":"10.1016/s1634-6939(18)78364-6","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine","score_opus":0.07741255948780984,"score_gpt":0.34378042683342913,"score_spread":0.2663678673456193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406554903","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008796726,0.0000803394,0.0000034035545,0.0007532531,0.000030973315,0.00062834955,0.000059525708,0.00035211866,0.9892953],"genre_scores_gemma":[0.0054594288,0.0000030015135,0.00006939962,0.00069479446,0.0005405471,0.000119895885,0.000030182526,0.000041414405,0.99304134],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981267,0.00039467178,0.00032113888,0.00040013803,0.0001814961,0.0005758637],"domain_scores_gemma":[0.99903464,0.00016242276,0.000062476254,0.0002890014,0.00006591032,0.0003855509],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0006236748,0.00027081682,0.00027654978,0.00014021616,0.00038856117,0.0000375993,0.0003285447,0.00045586567,0.998386],"category_scores_gemma":[0.00005695526,0.0002861334,0.0001222951,0.0003752151,0.00008997426,0.00016608373,0.00005747262,0.00086714164,0.99385124],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045521828,0.00020005999,0.0000011547038,0.000016256801,0.000068765585,0.00001822826,0.000075029464,0.00043278592,0.0030335751,0.0000038054834,0.2953899,0.7003052],"study_design_scores_gemma":[0.0007575412,0.00021982755,0.00003636617,0.0000124110575,0.000064749,0.000033365737,0.0000022318968,0.0009833227,0.011940609,0.0000615978,0.98554075,0.00034725043],"about_ca_topic_score_codex":0.000039377002,"about_ca_topic_score_gemma":0.0000010438839,"teacher_disagreement_score":0.69995797,"about_ca_system_score_codex":0.00009975217,"about_ca_system_score_gemma":0.000060461134,"threshold_uncertainty_score":0.9999591},"labels":[],"label_agreement":null},{"id":"W4406565706","doi":"10.1016/s9999-9919(14)00145-0","title":"10.1016/s9999-9919(14)00145-0","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Drug overdose; Medicine; Emergency medicine; Anesthesia; Medical emergency; Poison control","score_opus":0.05794133234906789,"score_gpt":0.33050893458125574,"score_spread":0.27256760223218784,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406565706","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009367252,0.00008010078,0.0000034740704,0.0009145233,0.000033701806,0.0006252872,0.00006122815,0.0003435635,0.98857087],"genre_scores_gemma":[0.0053897095,0.000003134817,0.00006777818,0.0006930327,0.0005648267,0.00012122261,0.00003298328,0.000040157196,0.9930872],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99813,0.0003901119,0.00031841404,0.00039959248,0.00018466111,0.00057718885],"domain_scores_gemma":[0.9990299,0.0001596167,0.00006328984,0.00029139966,0.00007349559,0.00038230262],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00064289843,0.00026983916,0.00027698404,0.00013621956,0.00039497012,0.000037745744,0.00033130863,0.00046548457,0.99725866],"category_scores_gemma":[0.00006339611,0.00028507714,0.00012018753,0.00036322576,0.000088391804,0.00016783022,0.000055865457,0.0009444687,0.993868],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044721438,0.00020699762,0.0000010277961,0.00001645864,0.000070433285,0.000018839892,0.000086628956,0.00045886333,0.0028955506,0.0000052159353,0.2100365,0.7857563],"study_design_scores_gemma":[0.00076809817,0.00021479817,0.0000307635,0.000012362121,0.00006392111,0.00003169748,0.0000019215624,0.00089099293,0.011500714,0.000065789514,0.9860725,0.00034644292],"about_ca_topic_score_codex":0.000035902714,"about_ca_topic_score_gemma":0.0000013002964,"teacher_disagreement_score":0.7854098,"about_ca_system_score_codex":0.00009646719,"about_ca_system_score_gemma":0.000057498295,"threshold_uncertainty_score":0.9999601},"labels":[],"label_agreement":null},{"id":"W4406579564","doi":"10.1016/s1541-9800(11)70562-2","title":"10.1016/s1541-9800(11)70562-2","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Drug; Drug overdose; Medicine; Medical emergency; Pharmacology; Poison control","score_opus":0.0590977304969231,"score_gpt":0.3304903843015167,"score_spread":0.27139265380459365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406579564","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016534735,0.000069388574,0.0000030888443,0.0009678945,0.000032111962,0.0006293182,0.000058282993,0.00034038478,0.9813648],"genre_scores_gemma":[0.006345945,0.0000024787475,0.00007340859,0.0006814282,0.0005411992,0.00011778737,0.00003087537,0.00004006086,0.9921668],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981369,0.00039767305,0.00031819654,0.00039685692,0.00018026627,0.000570132],"domain_scores_gemma":[0.99903977,0.0001718564,0.000061805724,0.00028797358,0.000063491745,0.0003751322],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00063741306,0.00026756743,0.0002726229,0.00013577197,0.00038827088,0.00003701564,0.00032954695,0.00045399586,0.9976316],"category_scores_gemma":[0.000057175203,0.00028277258,0.00012024676,0.0003594222,0.00008962009,0.00016125149,0.000057121833,0.0007468849,0.9931938],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039529643,0.0002324616,0.0000027209792,0.000019370933,0.0000645083,0.00002076916,0.000102284976,0.0005130342,0.002842052,0.000006855814,0.23465385,0.7611468],"study_design_scores_gemma":[0.0007277924,0.00018220753,0.000046730293,0.000012274361,0.0000632157,0.00003226093,0.0000023227988,0.0010180331,0.011211876,0.000059903083,0.9862998,0.0003435924],"about_ca_topic_score_codex":0.000054429107,"about_ca_topic_score_gemma":0.000002593636,"teacher_disagreement_score":0.7608032,"about_ca_system_score_codex":0.00010025943,"about_ca_system_score_gemma":0.0000610768,"threshold_uncertainty_score":0.99996245},"labels":[],"label_agreement":null},{"id":"W4406629472","doi":"10.1101/2025.01.20.25320827","title":"Genetic polymorphism and risk of anti-tuberculosis drug-induced liver injury (AT-DILI): a systematic review and meta-analysis","year":2025,"lang":"en","type":"review","venue":"medRxiv","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Meta-analysis; Liver injury; Drug; Medicine; Tuberculosis; Systematic review; Polymorphism (computer science); Internal medicine; Pharmacology; MEDLINE; Biology; Genetics; Genotype; Gene; Pathology","score_opus":0.14375448633031987,"score_gpt":0.4202499160687993,"score_spread":0.2764954297384794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406629472","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0053408043,0.9882347,0.0000084123985,0.000104770224,0.0002290289,0.0051039313,0.0007030562,0.00006479593,0.00021049049],"genre_scores_gemma":[0.00340373,0.9933552,0.000053882333,0.00048533222,0.000044080312,0.0013085051,0.00003203561,0.000051522147,0.0012657143],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9894965,0.0067154476,0.0019961637,0.0009981565,0.00031557103,0.000478148],"domain_scores_gemma":[0.99520427,0.0016447379,0.0018076614,0.0008873934,0.00015783362,0.00029809788],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0032611017,0.00092964596,0.00967785,0.000922839,0.00039191532,0.000030236495,0.00047313745,0.0009843156,0.00071419403],"category_scores_gemma":[0.00053740526,0.0006956829,0.0025420624,0.0017303576,0.00021700191,0.000092997594,0.00039506,0.0014900302,0.00006158307],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007890715,0.000112966154,0.0002730955,0.8216788,0.16808465,0.000022411728,0.00011015347,0.0000010981661,0.000023578015,0.000021156055,0.00012175491,0.009542423],"study_design_scores_gemma":[0.00016330506,0.000043428794,0.00007211812,0.011426257,0.9662568,0.000056528406,0.000005448156,0.000034537596,0.00019195893,0.00002567853,0.021140771,0.0005831459],"about_ca_topic_score_codex":0.00025342157,"about_ca_topic_score_gemma":0.00011742736,"teacher_disagreement_score":0.81025255,"about_ca_system_score_codex":0.000110236564,"about_ca_system_score_gemma":0.00015439258,"threshold_uncertainty_score":0.99954945},"labels":[],"label_agreement":null},{"id":"W4406646165","doi":"10.1016/b978-84-8086-959-1.00355-2","title":"10.1016/b978-84-8086-959-1.00355-2","year":2000,"lang":"en","type":"book-chapter","venue":"Time to knit","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine","score_opus":0.07066564238243146,"score_gpt":0.315895588383517,"score_spread":0.24522994600108555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406646165","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000013745965,0.00037586185,0.0000029320431,0.00045501062,0.00008248269,0.0013669928,0.0004499222,0.0004614108,0.99679166],"genre_scores_gemma":[0.00003186272,0.000013682989,0.000041517393,0.0006698366,0.0014531794,0.00012985595,0.00023547235,0.00018160761,0.997243],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971178,0.00023832731,0.000671496,0.00084127166,0.00036376336,0.0007673268],"domain_scores_gemma":[0.99814755,0.00026670558,0.00027363785,0.00057802204,0.00014286634,0.00059124536],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.00067106885,0.0008035711,0.0007863308,0.00043502066,0.0004673791,0.00006027684,0.0006098657,0.0022174956,0.9973831],"category_scores_gemma":[0.000047426754,0.00089427625,0.00036843037,0.00012315456,0.00019777624,0.00014188151,0.00017409677,0.0028560432,0.9950291],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058276876,0.000104090526,5.3452197e-8,0.000060783095,0.0003187132,0.000075554344,0.00005142327,0.00009136866,0.00043490558,0.00020179973,0.23680672,0.76127183],"study_design_scores_gemma":[0.0007130091,0.0003850033,0.0000010183488,0.000098348624,0.00034308262,0.00006438962,6.338554e-7,0.00015654534,0.0014414747,0.0009512663,0.9948802,0.000965004],"about_ca_topic_score_codex":0.000029345423,"about_ca_topic_score_gemma":0.0000026688872,"teacher_disagreement_score":0.76030684,"about_ca_system_score_codex":0.00026532175,"about_ca_system_score_gemma":0.00019021408,"threshold_uncertainty_score":0.9994444},"labels":[],"label_agreement":null},{"id":"W4406715359","doi":"10.1016/j.fct.2025.115277","title":"A proposed screening strategy for evaluating the genotoxicity potential of botanicals and botanical extracts","year":2025,"lang":"en","type":"review","venue":"Food and Chemical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"National Institute of Environmental Health Sciences; U.S. Food and Drug Administration; U.S. Department of Health and Human Services; National Institutes of Health; European Food Safety Authority; Health and Environmental Sciences Institute","keywords":"Genotoxicity; CAS Registry Number; Traditional medicine; Chemistry; Pharmacology; Computational biology; Toxicology; Biology; Medicine; Toxicity; Organic chemistry","score_opus":0.3128544692308305,"score_gpt":0.5100530476164312,"score_spread":0.19719857838560073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406715359","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.022753805,0.9695788,0.00095286773,0.0003240888,0.00064571394,0.004821763,0.00043038133,0.00008244392,0.0004101292],"genre_scores_gemma":[0.106728144,0.8899458,0.0010265089,0.00048440893,0.0006384248,0.0008134436,0.00008275542,0.000063044936,0.00021746595],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99586433,0.0012876308,0.0011748315,0.00080580596,0.00020018882,0.00066723925],"domain_scores_gemma":[0.9953707,0.0033046857,0.00065005047,0.00028906934,0.00013841101,0.00024711288],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0019258711,0.0005659921,0.001837338,0.00010633504,0.00043943696,0.000043567274,0.0004225589,0.0022792425,0.000081972874],"category_scores_gemma":[0.0009915141,0.00042075547,0.00045980068,0.00027529718,0.0006441172,0.000070480106,0.00034486369,0.0020577742,0.000002241369],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040987204,0.00029251314,0.0000025937566,0.009468318,0.0006869496,0.000005315942,0.000054213884,0.000008520566,0.0371563,0.0012321476,0.00012221301,0.95056105],"study_design_scores_gemma":[0.0072974474,0.008327302,0.00003274155,0.0059087467,0.011269475,0.00079312216,0.0001995614,0.0049847867,0.053871237,0.009811462,0.8951771,0.0023269926],"about_ca_topic_score_codex":0.000004668177,"about_ca_topic_score_gemma":0.000007504242,"teacher_disagreement_score":0.948234,"about_ca_system_score_codex":0.000067897105,"about_ca_system_score_gemma":0.00039759927,"threshold_uncertainty_score":0.9998244},"labels":[],"label_agreement":null},{"id":"W4406725300","doi":"10.1016/b978-84-9113-949-2.00088-3","title":"10.1016/b978-84-9113-949-2.00088-3","year":2000,"lang":"en","type":"book-chapter","venue":"Time to knit","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine","score_opus":0.07026925409188442,"score_gpt":0.3153674137284268,"score_spread":0.24509815963654238,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406725300","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000018850016,0.0004387239,0.0000021184946,0.00047631573,0.00008977877,0.0014008844,0.00044210991,0.00049387646,0.99663734],"genre_scores_gemma":[0.000042929765,0.000015126486,0.000036834626,0.0007108069,0.001523626,0.00013625275,0.00022576445,0.00019323023,0.99711543],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99701947,0.0002475259,0.0006945987,0.0008691368,0.00037835233,0.00079089135],"domain_scores_gemma":[0.99808806,0.00028096474,0.0002749494,0.00059785193,0.00014187144,0.00061632437],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.00068232697,0.00083187205,0.00081932935,0.0004541831,0.00047925254,0.000060599956,0.0006358504,0.0022575408,0.9974414],"category_scores_gemma":[0.000045215795,0.00092532224,0.00040020715,0.00012391996,0.00020715492,0.00014634905,0.00018063949,0.0029417342,0.9948122],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006828186,0.00011564805,5.0452847e-8,0.00006464239,0.0003667643,0.00008647422,0.000057701236,0.0001322446,0.00036460164,0.00020625094,0.19450323,0.8034196],"study_design_scores_gemma":[0.00075719156,0.00034183892,0.0000011850592,0.00009932585,0.00035214645,0.00007273596,6.415404e-7,0.00014037365,0.0014332143,0.0010710919,0.9947339,0.0009963241],"about_ca_topic_score_codex":0.00003196816,"about_ca_topic_score_gemma":0.0000027565532,"teacher_disagreement_score":0.80242324,"about_ca_system_score_codex":0.00028167458,"about_ca_system_score_gemma":0.00020305104,"threshold_uncertainty_score":0.99935853},"labels":[],"label_agreement":null},{"id":"W4407006763","doi":"10.51731/cjht.2025.1068","title":"Amivantamab (Rybrevant)","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Computer science","score_opus":0.13011247310058613,"score_gpt":0.4548316854798537,"score_spread":0.3247192123792676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407006763","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5704671,0.12722783,0.0038911754,0.26084858,0.014421572,0.001517402,0.00010814471,0.00069142465,0.020826764],"genre_scores_gemma":[0.9952246,0.0009927956,0.00021237167,0.0031403278,0.0000225441,0.0000100041325,0.0000014867504,0.000009069408,0.00038680306],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982934,0.00028493427,0.0006326403,0.00014538602,0.000083334584,0.00056031597],"domain_scores_gemma":[0.9990206,0.00015348184,0.00036610244,0.00018330423,0.00016322116,0.00011333815],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015529889,0.00015054386,0.0003645407,0.00097226456,0.0006309503,0.00002756367,0.00048202815,0.00047657816,0.000101702484],"category_scores_gemma":[0.0005851522,0.0001405628,0.00009841793,0.00057491555,0.00028988073,0.00012881595,0.000028331771,0.0016685181,0.000036113055],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036019774,0.00003362633,0.0058294055,0.00013509805,0.00009337902,0.000091273345,0.00024159829,0.000059458012,0.00069519447,0.00720881,0.018035384,0.96754074],"study_design_scores_gemma":[0.00064344745,0.00016930257,0.002644612,0.00014349267,0.0000265287,0.0001395334,0.001165318,0.000059539943,0.013837771,0.016129635,0.9649106,0.00013021633],"about_ca_topic_score_codex":0.001526796,"about_ca_topic_score_gemma":0.0028467055,"teacher_disagreement_score":0.96741056,"about_ca_system_score_codex":0.0005552789,"about_ca_system_score_gemma":0.0029074403,"threshold_uncertainty_score":0.7248973},"labels":[],"label_agreement":null},{"id":"W4407067743","doi":"10.1080/17425255.2025.2461484","title":"Evaluating the synergistic use of advanced liver models and AI for the prediction of drug-induced liver injury","year":2025,"lang":"en","type":"review","venue":"Expert Opinion on Drug Metabolism & Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Innovative Medicines Initiative; Ontario Institute for Cancer Research; Robert Bosch","keywords":"Liver injury; Drug; Medicine; Pharmacology","score_opus":0.3582357515422824,"score_gpt":0.5096603489358854,"score_spread":0.15142459739360303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407067743","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014326276,0.979115,0.0008117648,0.00059269485,0.010067081,0.0068824813,0.0008837941,0.0000856821,0.00012886609],"genre_scores_gemma":[0.0059093814,0.98737985,0.00035383264,0.0014654133,0.00090211787,0.003287253,0.0001015836,0.00007776098,0.0005228353],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99238235,0.00413549,0.0015791421,0.0008905914,0.00039584644,0.0006165961],"domain_scores_gemma":[0.9873552,0.009921456,0.001353956,0.0007989621,0.000425358,0.00014510169],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002651357,0.0007778392,0.0021363052,0.0004862789,0.000764891,0.000037357997,0.00075159624,0.0011995995,0.000098906225],"category_scores_gemma":[0.001250012,0.00051375263,0.0007071911,0.0006040754,0.00053432136,0.00031202196,0.00033795304,0.0020246175,0.0000073050464],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00066468754,0.00038116728,6.5321206e-7,0.0034279074,0.00070106453,0.000001232359,0.0017558316,0.0014346751,0.0016969928,0.008862693,0.0030042615,0.9780688],"study_design_scores_gemma":[0.0012709494,0.00039837544,0.0000122786205,0.0019021085,0.0010214837,0.000013541072,0.00013795555,0.022762077,0.004435043,0.00053651765,0.96708256,0.00042709112],"about_ca_topic_score_codex":0.0001254971,"about_ca_topic_score_gemma":0.000021798965,"teacher_disagreement_score":0.97764176,"about_ca_system_score_codex":0.00014246443,"about_ca_system_score_gemma":0.00064942095,"threshold_uncertainty_score":0.9997314},"labels":[],"label_agreement":null},{"id":"W4407285603","doi":"10.1093/jcag/gwae059.241","title":"A241 AMOXICILLIN-CLAVULANATE INDUCED LIVER INJURY WITH CONCOMITANT AMPULLARY STENOSIS: A CASE REPORT AND LITERATURE REVIEW","year":2025,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Concomitant; Amoxicillin; Stenosis; Medicine; Liver injury; Internal medicine; Antibiotics; Biology; Microbiology","score_opus":0.030883507098586328,"score_gpt":0.3358474976366985,"score_spread":0.3049639905381122,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407285603","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97763383,0.0012511009,0.000015325739,0.01915546,0.0011006542,0.00042517835,0.00007363966,0.0000060650123,0.0003387316],"genre_scores_gemma":[0.98486835,0.0023511306,0.000062166895,0.012231593,0.00009853802,0.000009331986,0.0000037762247,0.000009208142,0.00036591993],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99746215,0.001235581,0.00067561603,0.00014915406,0.00016928294,0.00030819883],"domain_scores_gemma":[0.99747723,0.00014518418,0.0013989192,0.0001579588,0.00060718606,0.0002135229],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0023378097,0.00015907957,0.0004753182,0.00028529772,0.00026430725,0.000022006227,0.00019215902,0.00038616153,0.00003212159],"category_scores_gemma":[0.00044310975,0.0001176089,0.00013622138,0.0002976478,0.00008306698,0.00012097846,0.00003904112,0.0013681629,0.0000010371152],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021336162,0.000255183,0.9143229,0.0012385412,0.0028779167,0.031133782,0.0012541993,0.00008506962,0.0046368595,0.00035928492,0.037614487,0.004088148],"study_design_scores_gemma":[0.023706522,0.009496831,0.41416678,0.017880026,0.008640112,0.3157023,0.00092516287,0.0010040574,0.015416671,0.0018992677,0.1897832,0.001379094],"about_ca_topic_score_codex":0.0013619015,"about_ca_topic_score_gemma":0.08945854,"teacher_disagreement_score":0.50015616,"about_ca_system_score_codex":0.00071333774,"about_ca_system_score_gemma":0.0005004521,"threshold_uncertainty_score":0.92715645},"labels":[],"label_agreement":null},{"id":"W4407349081","doi":"10.1111/liv.70022","title":"Acute Transient Aminotransferase Elevation is Common With Intrathecal Methotrexate, but Liver Injury is Infrequent","year":2025,"lang":"en","type":"article","venue":"Liver International","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health; Center for Cancer Research","keywords":"Medicine; Methotrexate; Internal medicine; Liver injury; Gastroenterology; Incidence (geometry); Liver enzyme; Retrospective cohort study","score_opus":0.07329254810326553,"score_gpt":0.40994283643202206,"score_spread":0.33665028832875654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407349081","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9658743,0.00010771544,0.011673709,0.0038304264,0.0017570407,0.0007043301,0.0006111479,0.0001279987,0.015313325],"genre_scores_gemma":[0.9822097,0.0004945671,0.0005874301,0.012426384,0.00020389006,0.00013622113,0.00011170899,0.000018866152,0.0038112213],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982811,0.000287379,0.00039299688,0.00041792783,0.00031594848,0.0003046004],"domain_scores_gemma":[0.9992073,0.00016091956,0.000103951206,0.00017988602,0.00023064743,0.00011728789],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00037766207,0.00027033399,0.00023498872,0.00027570786,0.00025805624,0.000059049828,0.00034832594,0.00037746516,0.0027949729],"category_scores_gemma":[0.000012785947,0.00025465357,0.00012698189,0.0002808712,0.00015971906,0.00033649817,0.00004736637,0.00096405455,0.00017273474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010086355,0.003306758,0.025865687,0.00033873058,0.0070530735,0.0005438592,0.01841402,0.00057307794,0.45007294,0.044890817,0.041043386,0.3978113],"study_design_scores_gemma":[0.0025845638,0.00030227043,0.008815761,0.00008436308,0.00044371522,0.000056397734,0.000101813326,0.016068613,0.78664774,0.0013472916,0.18310368,0.0004437757],"about_ca_topic_score_codex":0.0002638882,"about_ca_topic_score_gemma":0.00010076327,"teacher_disagreement_score":0.3973675,"about_ca_system_score_codex":0.00025142703,"about_ca_system_score_gemma":0.00012045343,"threshold_uncertainty_score":0.9999906},"labels":[],"label_agreement":null},{"id":"W4408191848","doi":"10.1080/15563650.2025.2471915","title":"Out-of-hospital assessment and triage of paracetamol (acetaminophen) exposure in the United States and Canada: a consensus guideline","year":2025,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Queen's University; University of Calgary","funders":"","keywords":"Guideline; Triage; Acetaminophen; Medicine; Clinical toxicology; Medical emergency; Emergency medicine; Emergency department; Intensive care medicine; Toxicology; Anesthesia; Nursing; Pathology","score_opus":0.15616268644495543,"score_gpt":0.4936217073510094,"score_spread":0.33745902090605395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408191848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98583746,0.00036213803,0.000097591575,0.009882422,0.002104877,0.0008705991,0.00008247902,0.000013263232,0.0007491825],"genre_scores_gemma":[0.99391496,0.0008160789,0.0003130691,0.0046316623,0.0000750498,0.00008356363,0.000029649076,0.000007694719,0.00012827829],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9954498,0.0024658358,0.0013383491,0.0003338561,0.000116190065,0.00029596454],"domain_scores_gemma":[0.9936986,0.0054471,0.00038148274,0.0002242117,0.00014894328,0.000099691206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0036730322,0.00018863346,0.0006448789,0.00013968715,0.0001128916,0.000007414618,0.00021200278,0.0005519181,0.00007054907],"category_scores_gemma":[0.0009953089,0.00014983273,0.00006899274,0.00026937557,0.0007406745,0.000025827743,0.00012260671,0.0011572527,7.4503197e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002232946,0.0038155003,0.88625854,0.0004925862,0.0010398767,0.00024013627,0.002331601,0.0007431096,0.006466857,0.013464556,0.028773472,0.054140832],"study_design_scores_gemma":[0.02125786,0.005735354,0.5705123,0.00014379446,0.00084772764,0.00002841867,0.0055873357,0.01825837,0.009240458,0.009596232,0.35800213,0.0007900191],"about_ca_topic_score_codex":0.0143157635,"about_ca_topic_score_gemma":0.07696388,"teacher_disagreement_score":0.32922867,"about_ca_system_score_codex":0.00006391005,"about_ca_system_score_gemma":0.0005842557,"threshold_uncertainty_score":0.992248},"labels":[],"label_agreement":null},{"id":"W4408294361","doi":"10.1097/lvt.0000000000000594","title":"Failure to rescue in acute liver failure: A multicenter cohort study","year":2025,"lang":"en","type":"article","venue":"Liver Transplantation","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta Hospital; Alberta Hospital Edmonton","funders":"","keywords":"Medicine; Liver transplantation; Complication; Retrospective cohort study; Surgery; Cohort; Sepsis; Cohort study; Internal medicine; Odds ratio; Transplantation","score_opus":0.04455313017145196,"score_gpt":0.3837102754765739,"score_spread":0.3391571453051219,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408294361","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99185485,0.00003800923,0.0020734188,0.00078157015,0.0006823725,0.0028619203,0.00007127814,0.000107266926,0.0015293122],"genre_scores_gemma":[0.9965704,0.00028402405,0.00041520514,0.0015538422,0.00006565822,0.00044761813,0.0000660103,0.000015174847,0.00058205886],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99803954,0.00063968037,0.00035514787,0.00044944484,0.00016890734,0.0003472649],"domain_scores_gemma":[0.9994481,0.00015503325,0.000046726724,0.0001697663,0.00007156336,0.000108817585],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006128979,0.00022225497,0.00024542093,0.0003713616,0.00021339097,0.000033676264,0.00020033409,0.00032904735,0.00029473027],"category_scores_gemma":[0.000016192056,0.00023453204,0.00006820232,0.00054161873,0.000037075482,0.00025009707,0.000025060906,0.0007765973,0.00027977183],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0039890325,0.0021497342,0.8923561,0.000507684,0.0008469174,0.0013089053,0.030179312,0.002327295,0.051659293,0.00068380043,0.0012760229,0.012715895],"study_design_scores_gemma":[0.006420106,0.0002995192,0.91489327,0.00013828826,0.0009663869,0.000033164113,0.0007938535,0.0043083914,0.059353463,0.00009522337,0.012213389,0.00048494045],"about_ca_topic_score_codex":0.00071682944,"about_ca_topic_score_gemma":0.010775207,"teacher_disagreement_score":0.029385459,"about_ca_system_score_codex":0.00013761448,"about_ca_system_score_gemma":0.00005234664,"threshold_uncertainty_score":0.9563939},"labels":[],"label_agreement":null},{"id":"W4408791372","doi":"10.3390/pharmaceutics17040407","title":"Solidago canadensis L. Herb Extract, Its Amino Acids Preparations and 3D-Printed Dosage Forms: Phytochemical, Technological, Molecular Docking and Pharmacological Research","year":2025,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"NordForsk; Eesti Teadusagentuur; European Commission","keywords":"Phytochemical; Antimicrobial; Traditional medicine; Herb; Antibacterial activity; Chemistry; Amino acid; Saponin; Enterococcus faecalis; Biology; Biochemistry; Bacteria; Microbiology; Medicine; Escherichia coli; Medicinal herbs","score_opus":0.2209183161611842,"score_gpt":0.5082421756202836,"score_spread":0.28732385945909944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408791372","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.975961,0.0040936987,0.0007255973,0.004539,0.00053259055,0.0019921188,0.00006896057,0.00043156333,0.011655462],"genre_scores_gemma":[0.9922895,0.003336125,0.00049778813,0.002585252,0.00012099753,0.00051324244,0.000020797946,0.000035249446,0.0006010827],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99580353,0.0010313619,0.00065901846,0.0009334756,0.00040076207,0.001171867],"domain_scores_gemma":[0.9976251,0.0010436559,0.00015992067,0.00031068778,0.00036428112,0.0004963415],"candidate_categories":["metaepi_narrow","sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0022859182,0.0004812117,0.0005065102,0.00051978085,0.0013341017,0.00016382433,0.0004692586,0.0010436546,0.00035052458],"category_scores_gemma":[0.0006671432,0.00046796785,0.00010340123,0.0011204398,0.0011007597,0.00029949623,0.0006637719,0.0038821413,0.000046618625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037008812,0.0005002207,0.0018314727,0.00024229448,0.0004091076,0.00014583566,0.0003668914,0.0002758757,0.9457972,0.004001971,0.0013067503,0.0447523],"study_design_scores_gemma":[0.0017481559,0.00009972917,0.00028868913,0.000062176754,0.0003448242,0.00008958197,0.00032473373,0.03076995,0.773662,0.0018438298,0.19033003,0.0004363408],"about_ca_topic_score_codex":0.00003742025,"about_ca_topic_score_gemma":0.00004508637,"teacher_disagreement_score":0.18902327,"about_ca_system_score_codex":0.0003114388,"about_ca_system_score_gemma":0.00022185477,"threshold_uncertainty_score":0.999966},"labels":[],"label_agreement":null},{"id":"W4408928307","doi":"10.1159/000545507","title":"LKM Immunofluorescence Is Associated with DILI, Especially after Metamizole Intake","year":2025,"lang":"en","type":"article","venue":"Digestive Diseases","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Medicine; Immunofluorescence; Metamizole; Internal medicine; Immunology; Pharmacology; Antibody","score_opus":0.0463090591246651,"score_gpt":0.3768496010326063,"score_spread":0.3305405419079412,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408928307","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98579216,0.0015226285,0.00019443237,0.0008563546,0.0008426211,0.00078131404,0.00063606916,0.00022911523,0.0091453055],"genre_scores_gemma":[0.9917808,0.00013394355,0.00002539506,0.0040757456,0.00010736315,0.0003825956,0.00008528317,0.000022978462,0.0033858796],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981107,0.00047599603,0.0002834954,0.00045418783,0.00020922086,0.00046640035],"domain_scores_gemma":[0.9987261,0.00045479785,0.00013363149,0.00023477108,0.0002569059,0.00019379263],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00023611535,0.0003130522,0.0003444384,0.00017309001,0.00041141725,0.00006190761,0.00026108453,0.00028355396,0.0010708168],"category_scores_gemma":[0.0003677591,0.0002775503,0.0001540608,0.00057171634,0.00034230165,0.00024901555,0.00009552517,0.00066434505,0.0001470115],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0061939247,0.002585254,0.91831243,0.000134587,0.0022730066,0.00033564944,0.0018032235,0.00019007754,0.010999703,0.002609209,0.006150922,0.048412036],"study_design_scores_gemma":[0.002216116,0.00020330978,0.89890736,0.00021909214,0.00082187814,0.000003559355,0.00021506299,0.0004195812,0.054979254,0.0011146935,0.040364653,0.00053545146],"about_ca_topic_score_codex":0.00005320242,"about_ca_topic_score_gemma":0.00004964058,"teacher_disagreement_score":0.047876585,"about_ca_system_score_codex":0.00020011257,"about_ca_system_score_gemma":0.00029602673,"threshold_uncertainty_score":0.9999677},"labels":[],"label_agreement":null},{"id":"W4409086172","doi":"10.1080/15563650.2025.2479721","title":"Paracetamol (acetaminophen) poisoning; consensus definitions of poisoning types and outcomes to be used in the clinical toxicology recommendations collaborative systematic review","year":2025,"lang":"en","type":"review","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre intégré de santé et de services sociaux de Chaudière-Appalaches; Centre Intégré de Santé et de Services Sociaux des Laurentides; Université de Sherbrooke","funders":"","keywords":"Medicine; Acetaminophen; Ingestion; Poison control; Workgroup; Clinical toxicology; Drug overdose; Nomogram; Analgesic; Anesthesia; Emergency medicine; Toxicology; Intensive care medicine; Pharmacology; Internal medicine","score_opus":0.5109327253996827,"score_gpt":0.5891535790671144,"score_spread":0.0782208536674317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409086172","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0016402833,0.9585073,0.00004094423,0.018953973,0.0041651726,0.013778219,0.00080965064,0.00011312325,0.0019913567],"genre_scores_gemma":[0.0011017093,0.9732902,0.0006969587,0.020743828,0.00018196728,0.0033343276,0.0001635314,0.000053113028,0.00043437487],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.96309423,0.028232746,0.0063438364,0.0012248534,0.00027346163,0.00083086715],"domain_scores_gemma":[0.9280397,0.06781642,0.002481038,0.00093600806,0.00036144324,0.00036538005],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.015028803,0.00089069805,0.007996533,0.0005940955,0.0004781143,0.00004471373,0.0010864679,0.0030310233,0.0003007982],"category_scores_gemma":[0.029530147,0.0006606331,0.0011577065,0.001855085,0.0010920146,0.00008425894,0.00045159404,0.0048424485,0.00015512021],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035825244,0.0061457483,0.004282432,0.7187653,0.006093122,0.00028059256,0.0016665576,0.00001810601,0.0000084764315,0.03246819,0.027502738,0.20241049],"study_design_scores_gemma":[0.0033410704,0.0023565355,0.0005745248,0.14521848,0.0160153,0.00025323706,0.0008776372,0.000043623862,0.000009152523,0.0014506048,0.8284177,0.0014421049],"about_ca_topic_score_codex":0.000015794018,"about_ca_topic_score_gemma":0.00050724525,"teacher_disagreement_score":0.800915,"about_ca_system_score_codex":0.00019550651,"about_ca_system_score_gemma":0.0014795642,"threshold_uncertainty_score":0.9995845},"labels":[],"label_agreement":null},{"id":"W4409126367","doi":"10.12688/f1000research.161606.1","title":"Assesing Conversion Rate, Treatment Success and Mortality of Drug Induce Liver Injury from First Line Antituberculosis Regiment: A Systematic Review and Meta -Analysis","year":2025,"lang":"en","type":"review","venue":"F1000Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Open peer review; Meta-analysis; Medicine; Liver injury; Plant biology; Drug; Pharmacology; First line; Intensive care medicine; Physiology; Internal medicine; Biology","score_opus":0.3148928827514283,"score_gpt":0.5224238734163019,"score_spread":0.20753099066487363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409126367","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014816289,0.9901806,0.000014103764,0.00021651309,0.0001190896,0.0062329164,0.0014828149,0.000043252465,0.00022909367],"genre_scores_gemma":[0.0033857527,0.9938125,0.000023049899,0.00017803922,0.00004294229,0.0009866791,0.00032604902,0.00003165081,0.0012133654],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99104327,0.0060572526,0.0012320519,0.0008642483,0.00037709723,0.00042610336],"domain_scores_gemma":[0.9950806,0.0029805533,0.0007190165,0.0006950614,0.00025575623,0.0002689963],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0037367325,0.0006252398,0.0058072372,0.0007764122,0.00043966793,0.00007705957,0.00042227822,0.0007142502,0.00077075965],"category_scores_gemma":[0.0003336491,0.00046379335,0.001079101,0.001676249,0.00027459965,0.00020430221,0.00040151627,0.001173844,0.000025655818],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031992367,0.0003321836,0.00015524434,0.8825988,0.10895117,0.00003599399,0.00014773362,0.0000017630856,0.000009004803,0.000035828496,0.00016931881,0.0075309523],"study_design_scores_gemma":[0.00042645552,0.0001349417,0.00003949641,0.03771596,0.9207216,0.000007823938,0.000022658254,0.00018085781,0.00089545664,0.000037420563,0.039294697,0.00052261405],"about_ca_topic_score_codex":0.0029159547,"about_ca_topic_score_gemma":0.00039588302,"teacher_disagreement_score":0.84488285,"about_ca_system_score_codex":0.00027252437,"about_ca_system_score_gemma":0.0003290366,"threshold_uncertainty_score":0.99978137},"labels":[],"label_agreement":null},{"id":"W4409252005","doi":"10.37349/emed.2025.1001302","title":"Vanishing bile duct syndrome in drug-induced liver injury: clinical and pathologic perspectives","year":2025,"lang":"en","type":"article","venue":"Exploration of Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Western University; Mount Sinai Hospital","funders":"","keywords":"Bile duct; Medicine; Liver injury; Drug; Gastroenterology; Internal medicine; Pathology; Pharmacology","score_opus":0.24446881013092703,"score_gpt":0.49010879478817027,"score_spread":0.24563998465724324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409252005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9845192,0.00086876814,0.00037052418,0.008888301,0.0014129655,0.000598646,0.0000061945393,0.00006325167,0.0032721893],"genre_scores_gemma":[0.99664116,0.00169075,0.00012330858,0.0009268571,0.00018537583,0.000065537264,0.000009111355,0.000008951668,0.00034895045],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99769974,0.0010109923,0.0006029873,0.00035425063,0.00013724959,0.00019477241],"domain_scores_gemma":[0.99897826,0.00048038253,0.00018419742,0.00015810214,0.00011390475,0.00008512782],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0027303204,0.00016070456,0.00040915926,0.0003372297,0.00013720493,0.000007640519,0.00012696223,0.000318488,0.00018825218],"category_scores_gemma":[0.00084398943,0.00014191882,0.00004600592,0.00047431982,0.0004049445,0.0003966247,0.00006443141,0.000902908,0.000016424996],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032042647,0.003314061,0.09231308,0.0009961226,0.0005168431,0.0008676453,0.094218425,0.00023825662,0.2919869,0.10458656,0.012367135,0.3953907],"study_design_scores_gemma":[0.04553225,0.009518643,0.3261908,0.0030101193,0.0010935735,0.00039878825,0.12634689,0.013024884,0.22535755,0.13425376,0.112581566,0.0026911916],"about_ca_topic_score_codex":0.000113656955,"about_ca_topic_score_gemma":0.00009912888,"teacher_disagreement_score":0.3926995,"about_ca_system_score_codex":0.00005182848,"about_ca_system_score_gemma":0.000073900184,"threshold_uncertainty_score":0.57872814},"labels":[],"label_agreement":null},{"id":"W4409603286","doi":"10.1080/17425255.2025.2495955","title":"DILI prediction in drug development: present and future","year":2025,"lang":"en","type":"review","venue":"Expert Opinion on Drug Metabolism & Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Drug development; Drug; Medicine; Intensive care medicine; Pharmacology","score_opus":0.11548341045726622,"score_gpt":0.4469003716693024,"score_spread":0.3314169612120362,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409603286","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00018760747,0.96638554,0.000014599319,0.0016907608,0.02159522,0.0034041356,0.00017018602,0.00025755723,0.0062944093],"genre_scores_gemma":[0.00007169966,0.985701,0.00018727504,0.0014595083,0.005742923,0.0028286162,0.00039116465,0.00009262163,0.0035251947],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9913767,0.004019046,0.0016660929,0.0015163381,0.00037069968,0.0010511084],"domain_scores_gemma":[0.9971491,0.0011629697,0.0006138262,0.00057710183,0.00009540794,0.000401566],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0018606347,0.001163819,0.0026652035,0.0014504561,0.00061540195,0.00006312799,0.0006774462,0.002422486,0.00075133186],"category_scores_gemma":[0.00012445152,0.0010696071,0.00040731876,0.0009793686,0.00025988065,0.00024781912,0.0004139615,0.0037981917,0.00023648435],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014937916,0.0006589828,0.000009112139,0.0027838035,0.0002965504,0.000022258679,0.0022907958,0.00001176214,0.000019849023,0.0021596074,0.02023548,0.9713624],"study_design_scores_gemma":[0.0015334891,0.000047999438,0.00008686273,0.001734264,0.00011428245,0.000046873236,0.00016841394,0.000046233545,0.0004705097,0.00014087575,0.9948338,0.00077634584],"about_ca_topic_score_codex":0.00006249701,"about_ca_topic_score_gemma":0.000067967085,"teacher_disagreement_score":0.97459835,"about_ca_system_score_codex":0.0004660867,"about_ca_system_score_gemma":0.0009182705,"threshold_uncertainty_score":0.9991754},"labels":[],"label_agreement":null},{"id":"W4410168824","doi":"10.1080/15563650.2025.2493732","title":"Comment on “out-of-hospital assessment and triage of paracetamol (acetaminophen) exposure in the United States and Canada”","year":2025,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Triage; Acetaminophen; Medicine; Emergency medicine; Clinical toxicology; Medical emergency; Anesthesia; Toxicology","score_opus":0.1552951393266598,"score_gpt":0.48561528769670853,"score_spread":0.33032014837004875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410168824","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9744817,0.0001388269,0.0000490281,0.021464687,0.0019411992,0.0008713599,0.000053217373,0.0000103943,0.0009895626],"genre_scores_gemma":[0.982936,0.00087716785,0.000068780515,0.015856864,0.00005355525,0.00011414602,0.000022740709,0.000006687257,0.00006405936],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99592185,0.0025356081,0.00085227855,0.00030160643,0.000120891455,0.00026778804],"domain_scores_gemma":[0.9934612,0.0058868034,0.0002790749,0.00021787231,0.00006547077,0.00008959811],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0027567393,0.00017667006,0.00053977495,0.00013034572,0.00012172546,0.000007820662,0.00021660447,0.00046068078,0.00006135409],"category_scores_gemma":[0.00041129577,0.00013763378,0.00006159983,0.00021547008,0.0004938748,0.00003158714,0.000105019666,0.0012081983,9.756499e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025134753,0.0065514045,0.8728288,0.0005079059,0.00087506487,0.0001176736,0.0029063185,0.00055904617,0.002193731,0.038517885,0.02225419,0.0501745],"study_design_scores_gemma":[0.012809569,0.0071467096,0.59015083,0.00013938801,0.0003810387,0.0000049294576,0.0027354117,0.004287876,0.009913861,0.0056756623,0.36628148,0.00047321958],"about_ca_topic_score_codex":0.007438267,"about_ca_topic_score_gemma":0.027451178,"teacher_disagreement_score":0.34402728,"about_ca_system_score_codex":0.00007860791,"about_ca_system_score_gemma":0.00027062948,"threshold_uncertainty_score":0.9991713},"labels":[],"label_agreement":null},{"id":"W4410496241","doi":"10.1053/j.gastro.2025.03.056","title":"Development of Acute Kidney Injury in a Patient With Alcohol-Related Cirrhosis: The Importance of Diagnosing the Cause of Acute Kidney Injury","year":2025,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Liver Centre; University Health Network","funders":"National Institutes of Health; Grifols; Instituto de Salud Carlos III; National Institute of Diabetes and Digestive and Kidney Diseases; Gilead Sciences; Pfizer","keywords":"Acute kidney injury; Medicine; Cirrhosis; Intensive care medicine; Alcohol; Internal medicine","score_opus":0.03609183213967293,"score_gpt":0.36205643914177726,"score_spread":0.32596460700210433,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410496241","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941221,0.000027378966,0.00013040581,0.0034397955,0.0006857169,0.00094871415,0.0003926273,0.00002299753,0.00023029033],"genre_scores_gemma":[0.99309146,0.00015600899,0.00031777393,0.0060591525,0.000015181514,0.0002685949,0.00004498337,0.00001671246,0.000030146182],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99719566,0.00077492703,0.0010470402,0.00032614972,0.00017151338,0.0004847318],"domain_scores_gemma":[0.99855804,0.000110752735,0.00071584946,0.00036814407,0.00013868355,0.000108508735],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000911032,0.00026455667,0.00051922497,0.00025769306,0.00018007914,0.000005331848,0.000432409,0.0003085481,0.000090677924],"category_scores_gemma":[0.00008034755,0.0001782979,0.00011001145,0.000506926,0.0005227047,0.000085360036,0.0002199106,0.00095664116,0.00000307613],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0068214643,0.0009813402,0.8494134,0.00016902517,0.0043583685,0.00004721047,0.006895395,0.00005208875,0.12168201,0.00044230858,0.0039038989,0.0052334727],"study_design_scores_gemma":[0.0065752873,0.0024859754,0.2289292,0.00062240683,0.002169123,0.00013810395,0.00044382774,0.00061711244,0.7455378,0.0007434379,0.011368839,0.00036885872],"about_ca_topic_score_codex":0.00004843352,"about_ca_topic_score_gemma":0.00007256474,"teacher_disagreement_score":0.6238558,"about_ca_system_score_codex":0.000103570186,"about_ca_system_score_gemma":0.00036100298,"threshold_uncertainty_score":0.7270777},"labels":[],"label_agreement":null},{"id":"W4410646231","doi":"10.51731/cjht.2025.1131","title":"Amivantamab (Rybrevant)","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Geology","score_opus":0.13011247310058613,"score_gpt":0.4548316854798537,"score_spread":0.3247192123792676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410646231","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5704671,0.12722783,0.0038911754,0.26084858,0.014421572,0.001517402,0.00010814471,0.00069142465,0.020826764],"genre_scores_gemma":[0.9952246,0.0009927956,0.00021237167,0.0031403278,0.0000225441,0.0000100041325,0.0000014867504,0.000009069408,0.00038680306],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982934,0.00028493427,0.0006326403,0.00014538602,0.000083334584,0.00056031597],"domain_scores_gemma":[0.9990206,0.00015348184,0.00036610244,0.00018330423,0.00016322116,0.00011333815],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015529889,0.00015054386,0.0003645407,0.00097226456,0.0006309503,0.00002756367,0.00048202815,0.00047657816,0.000101702484],"category_scores_gemma":[0.0005851522,0.0001405628,0.00009841793,0.00057491555,0.00028988073,0.00012881595,0.000028331771,0.0016685181,0.000036113055],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036019774,0.00003362633,0.0058294055,0.00013509805,0.00009337902,0.000091273345,0.00024159829,0.000059458012,0.00069519447,0.00720881,0.018035384,0.96754074],"study_design_scores_gemma":[0.00064344745,0.00016930257,0.002644612,0.00014349267,0.0000265287,0.0001395334,0.001165318,0.000059539943,0.013837771,0.016129635,0.9649106,0.00013021633],"about_ca_topic_score_codex":0.001526796,"about_ca_topic_score_gemma":0.0028467055,"teacher_disagreement_score":0.96741056,"about_ca_system_score_codex":0.0005552789,"about_ca_system_score_gemma":0.0029074403,"threshold_uncertainty_score":0.7248973},"labels":[],"label_agreement":null},{"id":"W4410789528","doi":"10.3350/cmh.2025.0548","title":"Rising drug overdose deaths in chronic liver disease in the United States, 2015–2023","year":2025,"lang":"en","type":"article","venue":"Clinical and Molecular Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"British Columbia Centre on Substance Use; University of British Columbia","funders":"","keywords":"Medicine; Drug; Liver disease; Chronic liver disease; Drug overdose; Disease; Internal medicine; Intensive care medicine; Environmental health; Cirrhosis; Pharmacology; Poison control","score_opus":0.09886042436306193,"score_gpt":0.464816785718211,"score_spread":0.3659563613551491,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410789528","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98587966,0.004710455,0.00031875077,0.007054086,0.00073346525,0.00063133216,0.000020044316,0.00003382671,0.0006183903],"genre_scores_gemma":[0.9788648,0.005555233,0.000023341196,0.01515217,0.0000669489,0.00009126769,0.000060248225,0.000011024707,0.00017496018],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9955841,0.0028165886,0.0006088726,0.00045512267,0.000088291854,0.00044705343],"domain_scores_gemma":[0.99834335,0.0011120335,0.00009392595,0.00025351153,0.000040896055,0.00015626564],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018048533,0.00020488033,0.00036129294,0.00028247587,0.00016071653,0.000020587535,0.00026030262,0.0004540686,0.00007400791],"category_scores_gemma":[0.00037108507,0.0001720775,0.0001100623,0.0006141323,0.00043670152,0.000057567682,0.00015041027,0.0016435616,0.000039792052],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018387601,0.001615712,0.9146771,0.0004554718,0.00023232853,0.0038316138,0.0010757725,0.0020755352,0.0012480972,0.022767622,0.007534994,0.042647038],"study_design_scores_gemma":[0.008935349,0.0002908152,0.19380859,0.00024801277,0.00038143084,0.00004421953,0.00021216887,0.15277185,0.002014879,0.036085002,0.6044535,0.0007541999],"about_ca_topic_score_codex":0.0014173685,"about_ca_topic_score_gemma":0.0018309283,"teacher_disagreement_score":0.72086847,"about_ca_system_score_codex":0.000094787436,"about_ca_system_score_gemma":0.00026900173,"threshold_uncertainty_score":0.7140549},"labels":[],"label_agreement":null},{"id":"W4410893407","doi":"10.1080/15563650.2025.2505128","title":"Authors’ reply to comment on Fox et al. “Out-of-hospital assessment and triage of paracetamol (acetaminophen) exposure in the United States and Canada: a consensus guideline”","year":2025,"lang":"en","type":"article","venue":"Clinical Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Johnson and Johnson","keywords":"Guideline; Triage; Acetaminophen; Medicine; Medical emergency; Clinical toxicology; Emergency medicine; Anesthesia; Toxicology; Pathology","score_opus":0.17710225106050367,"score_gpt":0.5095710522828998,"score_spread":0.3324688012223961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410893407","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7915989,0.00009788443,0.00011863886,0.20438814,0.0019586263,0.0012074198,0.00009303442,0.000014208884,0.0005231076],"genre_scores_gemma":[0.8021179,0.00030173798,0.0004223547,0.1968444,0.00003115579,0.00015064357,0.00002935846,0.000009260163,0.000093192946],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9938157,0.00380219,0.0014266806,0.00045473868,0.00016553907,0.00033515337],"domain_scores_gemma":[0.9918903,0.0071254782,0.00037254614,0.00031907947,0.00014952126,0.00014304776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006038452,0.00022986185,0.0006826041,0.00018386621,0.00012909643,0.000011655757,0.00024367083,0.00039528828,0.000056478457],"category_scores_gemma":[0.0014330331,0.00018533948,0.00007626249,0.00025972945,0.00040171834,0.000022678678,0.0001643485,0.0013827052,0.0000013889874],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004718541,0.005478316,0.17730391,0.00026266745,0.0009985744,0.00023483906,0.0045183552,0.0016728659,0.003638298,0.019879507,0.7433107,0.03798342],"study_design_scores_gemma":[0.005253534,0.0038463932,0.053138394,0.000073799085,0.0001536485,0.0000051065385,0.0012210244,0.002385767,0.0028230958,0.0019506881,0.9288933,0.00025520683],"about_ca_topic_score_codex":0.016858803,"about_ca_topic_score_gemma":0.028068319,"teacher_disagreement_score":0.18558265,"about_ca_system_score_codex":0.00010819836,"about_ca_system_score_gemma":0.00049664965,"threshold_uncertainty_score":0.98968804},"labels":[],"label_agreement":null},{"id":"W4410946750","doi":"10.1021/acsomega.5c00222","title":"Liver–Skin Microphysiological System for Evaluating Topical Drug Delivery-Induced Liver Injury","year":2025,"lang":"en","type":"article","venue":"ACS Omega","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Guangdong Academy of Sciences; Natural Science Foundation of Hubei Province","keywords":"Liver injury; Drug; Drug delivery; Pharmacology; Medicine; Business; Chemistry","score_opus":0.1374959234998483,"score_gpt":0.43027086279585197,"score_spread":0.2927749392960037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410946750","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923003,0.00043252442,0.00038947802,0.0003915574,0.002609738,0.0014485773,0.000056872515,0.00023519869,0.0021358095],"genre_scores_gemma":[0.9954081,0.00010325041,0.0005892106,0.001801004,0.0005569891,0.00042699362,0.000026457019,0.000020715563,0.0010672685],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99737513,0.0008148786,0.000475184,0.00055555,0.0001635819,0.00061569887],"domain_scores_gemma":[0.99831784,0.0008677352,0.00015549321,0.00027476996,0.00022736436,0.00015679798],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011799046,0.00029908092,0.00041457004,0.00016852375,0.0007154327,0.000050859733,0.00039482818,0.0006811239,0.00006168552],"category_scores_gemma":[0.0002233821,0.00028245768,0.00021432072,0.0003269198,0.000104737184,0.00016202293,0.00019764439,0.0010093864,0.00019861235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013410962,0.0003400592,0.0005141657,0.0005609308,0.00024196586,0.000027250842,0.00060798327,0.000059932852,0.81665295,0.004782341,0.004865046,0.1700063],"study_design_scores_gemma":[0.0026147198,0.00058487244,0.002658355,0.0001451697,0.00032339976,0.000018322862,0.0003437166,0.01304999,0.9042507,0.0011555015,0.07429327,0.0005619794],"about_ca_topic_score_codex":0.00019138139,"about_ca_topic_score_gemma":0.000036377045,"teacher_disagreement_score":0.16944432,"about_ca_system_score_codex":0.00031685387,"about_ca_system_score_gemma":0.00016786807,"threshold_uncertainty_score":0.99996275},"labels":[],"label_agreement":null},{"id":"W4411273222","doi":"10.1016/j.jbc.2025.109031","title":"Abstract 1469 Biochemical screening of phytochemicals and identification of a potential inhibitor of SARS-CoV-2 Mpro and investigating its thermodynamic impact on the structural stability","year":2025,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Identification (biology); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); Metabolic stability; Chemistry; Biochemistry; Biology; Medicine; In vitro; Botany; Internal medicine","score_opus":0.13179705386718998,"score_gpt":0.4162621698765376,"score_spread":0.2844651160093476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411273222","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99897015,0.00033696042,0.000051770996,0.00021698253,0.00006947244,0.00018362084,0.00006538503,0.0000053939066,0.00010025365],"genre_scores_gemma":[0.9997322,0.00005629807,0.00007573707,0.000051914976,0.00007056809,0.0000034156153,0.000004430032,0.0000038405096,0.0000016290822],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986043,0.00016810182,0.0007868874,0.00016456733,0.00013443426,0.0001417003],"domain_scores_gemma":[0.9982408,0.0004963419,0.00089865335,0.000104184175,0.0002038887,0.000056120945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011450527,0.00014929191,0.00036516035,0.000038457303,0.000072977855,0.000009088826,0.00016882934,0.000404655,0.000040007584],"category_scores_gemma":[0.00084867916,0.00009147187,0.00014409359,0.00014237146,0.0005343026,0.000056823952,0.00007214015,0.0008008776,8.729461e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005377398,0.0000954238,0.006823818,0.00026635025,0.000107463755,9.970436e-7,0.000087997876,0.00003233313,0.99028045,0.000012931922,0.000012735791,0.001741758],"study_design_scores_gemma":[0.00048488282,0.00009652385,0.036068067,0.000121242156,0.000052584688,0.000018368906,0.00011427562,0.0030895073,0.95891315,0.00096747396,0.0000020869863,0.000071809474],"about_ca_topic_score_codex":0.000006537153,"about_ca_topic_score_gemma":1.3521517e-7,"teacher_disagreement_score":0.031367276,"about_ca_system_score_codex":0.000035075114,"about_ca_system_score_gemma":0.000059355054,"threshold_uncertainty_score":0.37301147},"labels":[],"label_agreement":null},{"id":"W4411656944","doi":"10.51847/leqxryewlf","title":"10.51847/leqXrYEwlf","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Traditional medicine; Oxalate; Chemistry; Pharmacology; Medicine; Organic chemistry","score_opus":0.0650692383997908,"score_gpt":0.3434754782528041,"score_spread":0.2784062398530133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411656944","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.02523264,0.000052974192,0.0000021401977,0.0010290092,0.000042001164,0.0004887294,0.000037630667,0.00028740085,0.9728275],"genre_scores_gemma":[0.0113704875,0.000003236388,0.000058640217,0.0010316098,0.00039707363,0.000088706365,0.000019983034,0.000028664148,0.9870016],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985791,0.00029073714,0.00023970312,0.00030603123,0.0001369265,0.0004474895],"domain_scores_gemma":[0.9992709,0.000118567856,0.000041206236,0.00022288506,0.00003772348,0.0003087009],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004929605,0.00019943544,0.00020531153,0.00010560975,0.0003017989,0.000026905076,0.00024979998,0.00033792606,0.9940389],"category_scores_gemma":[0.000037070797,0.00021015778,0.000088632405,0.00029808885,0.000062218176,0.00012583863,0.000040104595,0.00059112225,0.98323524],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036333315,0.00015362319,0.000001906495,0.00001045712,0.000049228387,0.000014723727,0.0000670123,0.00043858957,0.0035269584,0.000011652876,0.021754466,0.9736081],"study_design_scores_gemma":[0.00055755384,0.00017102643,0.00004342066,0.000007866436,0.000042614938,0.000024781604,0.0000011814404,0.0008407441,0.0053162836,0.000026760868,0.9927103,0.0002574953],"about_ca_topic_score_codex":0.000038239094,"about_ca_topic_score_gemma":7.521023e-7,"teacher_disagreement_score":0.9733505,"about_ca_system_score_codex":0.00007007618,"about_ca_system_score_gemma":0.00004250747,"threshold_uncertainty_score":0.85699856},"labels":[],"label_agreement":null},{"id":"W4411660550","doi":"10.51847/f8yxwoqqsz","title":"10.51847/f8YXWOqqSz","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Acetaminophen; Liver failure; Medicine; Internal medicine; Pharmacology","score_opus":0.06573417172335891,"score_gpt":0.3441372807386639,"score_spread":0.27840310901530496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411660550","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.030390846,0.000054316988,0.000002178602,0.00083270355,0.00004123361,0.00049368886,0.000037725185,0.00028825458,0.967859],"genre_scores_gemma":[0.014514687,0.0000031323204,0.0000583587,0.001065763,0.00038989948,0.00008854506,0.000019881918,0.000028691935,0.98383105],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985694,0.00029730838,0.00024076235,0.00030616575,0.00013724921,0.00044906986],"domain_scores_gemma":[0.999257,0.000121066034,0.000041319432,0.00022235647,0.000048037364,0.00031017585],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004968327,0.00020002162,0.00020633943,0.00010529475,0.00030372068,0.000026781281,0.00024809595,0.00033870028,0.9939854],"category_scores_gemma":[0.000041997562,0.0002106499,0.00008879375,0.00030282824,0.00006289321,0.00012520504,0.000039609593,0.0005937411,0.9831551],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036990622,0.00015866212,0.0000023088837,0.000010934761,0.000048874746,0.00001456204,0.00006897398,0.0004271404,0.004263831,0.0000083688565,0.025969716,0.9686567],"study_design_scores_gemma":[0.00055470236,0.00017534594,0.00006033646,0.000007937706,0.000042914886,0.000024339442,0.0000014220411,0.0008653117,0.005356879,0.000023833185,0.9926277,0.00025932404],"about_ca_topic_score_codex":0.000028243441,"about_ca_topic_score_gemma":6.370319e-7,"teacher_disagreement_score":0.9683974,"about_ca_system_score_codex":0.000072067196,"about_ca_system_score_gemma":0.000042918422,"threshold_uncertainty_score":0.8590054},"labels":[],"label_agreement":null},{"id":"W4411671071","doi":"10.1016/j.jamda.2025.105722","title":"Usage and Costs of Regular Acetaminophen (Paracetamol) in Canadian Long-Term Care Facilities","year":2025,"lang":"en","type":"article","venue":"Journal of the American Medical Directors Association","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Western University; Alberta Health Services; Alberta Health; University of Alberta","funders":"Pfizer Canada; University of Alberta; Pfizer","keywords":"Medicine; Acetaminophen; Term (time); Long-term care; Medical emergency; Emergency medicine; Intensive care medicine; Anesthesia; Nursing","score_opus":0.02642257200111839,"score_gpt":0.3733549018168054,"score_spread":0.346932329815687,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411671071","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99435145,0.0007332751,0.00001473148,0.002701743,0.00096749864,0.00018921506,0.000025181916,0.000005955451,0.0010109599],"genre_scores_gemma":[0.99817467,0.0005322588,0.000013974184,0.0006998114,0.000089235895,0.00000511339,0.0000022660668,0.000005347826,0.00047733125],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9976335,0.0011378387,0.00046548605,0.00010564408,0.00038192808,0.00027559238],"domain_scores_gemma":[0.99823684,0.0005789965,0.0006990913,0.000089061316,0.00017047938,0.0002255086],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019801988,0.0001098943,0.00038480246,0.00024596145,0.00013466917,0.000012820382,0.0002413254,0.00023012422,0.000076152246],"category_scores_gemma":[0.0021860679,0.000086656306,0.00010909194,0.00044897335,0.00021143178,0.00008573081,0.000043599706,0.00092622626,0.0000014312199],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007779718,0.000049643284,0.91607726,0.000049964063,0.00014972259,0.0000123092605,0.0012513128,0.000026548332,0.0020542326,0.000054238015,0.0004464744,0.079750516],"study_design_scores_gemma":[0.00081995147,0.000085971915,0.982843,0.0002046406,0.000111900685,0.000009303844,0.0005590652,0.00014183074,0.009269823,0.000092942384,0.0057634134,0.000098178585],"about_ca_topic_score_codex":0.042066876,"about_ca_topic_score_gemma":0.08318469,"teacher_disagreement_score":0.07965234,"about_ca_system_score_codex":0.0014720106,"about_ca_system_score_gemma":0.0006021135,"threshold_uncertainty_score":0.9643121},"labels":[],"label_agreement":null},{"id":"W4412136497","doi":"10.1021/acscentsci.5c00576","title":"Carbamate Prodrugs Restrict <i>In Vivo</i> Metabolism and Improve the Pharmacokinetics of Isoniazid","year":2025,"lang":"en","type":"article","venue":"ACS Central Science","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Department of Science and Technology, Ministry of Science and Technology, India; Biotechnology Industry Research Assistance Council; Translational Health Science and Technology Institute; Department of Biotechnology, Ministry of Science and Technology, India","keywords":"Prodrug; Pharmacokinetics; In vivo; Carbamate; Pharmacology; Isoniazid; Chemistry; Medicine; Virology; Biochemistry; Biology; Pathology; Biotechnology; Tuberculosis","score_opus":0.03829752533773941,"score_gpt":0.38131088776783156,"score_spread":0.3430133624300922,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412136497","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887296,0.00067525345,0.000029826653,0.002078139,0.0017470837,0.0007410177,0.000029847284,0.000029641064,0.005939621],"genre_scores_gemma":[0.99726856,0.0008740476,0.00006151203,0.0012869114,0.000071928946,0.0000382351,4.777513e-7,0.000005278774,0.00039306926],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983028,0.00022870817,0.00030936662,0.0003480474,0.00021680501,0.0005942648],"domain_scores_gemma":[0.9992895,0.00018885982,0.00012105515,0.00019256375,0.0000874802,0.0001205081],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001443374,0.00015001981,0.0001919238,0.00015568701,0.00035722283,0.00003809941,0.00048431402,0.00012894391,0.0000348624],"category_scores_gemma":[0.00017036838,0.00011277483,0.000036489047,0.0012733581,0.0008868555,0.0002197523,0.00018109671,0.0006181154,0.0000032144505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009680062,0.00011348267,0.008911352,0.000053069703,0.000020039797,0.000003968908,0.0010872659,0.00021950483,0.9585816,0.005761399,0.00034878714,0.024802685],"study_design_scores_gemma":[0.00079634803,0.000026704856,0.020613883,0.00001849273,0.0000605806,0.000004069608,0.00012601877,0.0032931676,0.93262255,0.0009858108,0.04132737,0.0001250137],"about_ca_topic_score_codex":0.0002432412,"about_ca_topic_score_gemma":0.000049957605,"teacher_disagreement_score":0.04097858,"about_ca_system_score_codex":0.00007120631,"about_ca_system_score_gemma":0.0002659536,"threshold_uncertainty_score":0.4598824},"labels":[],"label_agreement":null},{"id":"W4412196015","doi":"10.3390/curroncol32070393","title":"The Effect of Prophylactic Hepatoprotective Therapy on Drug-Induced Liver Injury in Patients Undergoing Chemotherapy for Cervical Cancer: A Retrospective Analysis Based on Propensity Score Matching","year":2025,"lang":"en","type":"article","venue":"Current Oncology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Internal medicine; Liver injury; Incidence (geometry); Propensity score matching; Chemotherapy; Retrospective cohort study; Cervical cancer; Adverse effect; Common Terminology Criteria for Adverse Events; Liver cancer; Drug; Gastroenterology; Cancer; Surgery; Pharmacology","score_opus":0.12120954610312813,"score_gpt":0.44714521406545504,"score_spread":0.3259356679623269,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412196015","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913394,0.00011641255,0.00023491977,0.0007491503,0.0019115651,0.005223753,0.00004827824,0.000049899507,0.00032662752],"genre_scores_gemma":[0.9974116,0.0001945555,0.0000115619305,0.000539271,0.000111326386,0.001670434,0.000014987193,0.000023870285,0.000022364786],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99587667,0.0022763012,0.00050099747,0.0006168603,0.00023849093,0.0004906566],"domain_scores_gemma":[0.996818,0.0021200068,0.00042660342,0.00030961234,0.00024304319,0.00008272082],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0018139653,0.00036182956,0.0007843424,0.00050653407,0.00056131236,0.000022909033,0.00031525298,0.00042941683,0.000036198933],"category_scores_gemma":[0.000304421,0.0002617625,0.00031842897,0.0011458937,0.00016530055,0.000075327895,0.00005311348,0.0016040404,0.000004861639],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.021936929,0.0016030886,0.64689463,0.00028288524,0.0006110806,0.0000021452772,0.0007314299,0.00096275535,0.0017735742,0.00024790733,0.000056866986,0.3248967],"study_design_scores_gemma":[0.015887266,0.010166755,0.7545585,0.00025317108,0.00054090406,2.6782484e-7,0.00003573758,0.016081188,0.19831802,0.0012372578,0.002456144,0.0004647822],"about_ca_topic_score_codex":0.00022575738,"about_ca_topic_score_gemma":0.0008497357,"teacher_disagreement_score":0.32443193,"about_ca_system_score_codex":0.0014817193,"about_ca_system_score_gemma":0.00037558086,"threshold_uncertainty_score":0.99998343},"labels":[],"label_agreement":null},{"id":"W4413116840","doi":"10.15441/ceem.25.059","title":"The role of fomepizole in acetaminophen-related poisoning: a narrative review","year":2025,"lang":"en","type":"review","venue":"Clinical and Experimental Emergency Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"","keywords":"Medicine; Acetaminophen; Acetylcysteine; acetaminophen overdose; Antidote; Dosing; Intensive care medicine; Toxicity; Pharmacology; Internal medicine","score_opus":0.2266660087859508,"score_gpt":0.5742193298481821,"score_spread":0.34755332106223136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413116840","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000728357,0.98232144,4.2544355e-7,0.00047808746,0.0038959056,0.0017424453,0.000015020167,0.000026230035,0.010792104],"genre_scores_gemma":[0.001641884,0.9952791,0.0000037988787,0.00019145035,0.0002485977,0.000412135,0.000042011972,0.000019047258,0.002162006],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99419606,0.0020299638,0.0027416996,0.0005025224,0.00017876217,0.00035097112],"domain_scores_gemma":[0.99744445,0.0012433539,0.0007676361,0.00028490552,0.00006544548,0.00019421718],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0027555039,0.0004315764,0.00214747,0.0001230201,0.0002890915,0.0000020676057,0.0003730419,0.00077905983,0.0013361248],"category_scores_gemma":[0.00094211986,0.00026659825,0.0004247918,0.0006603382,0.0007566061,0.0000554286,0.00019191758,0.0019263177,0.000025134148],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009474784,0.00045872724,0.00022099508,0.012374182,0.00043081204,0.000006095603,0.0012813362,2.5472016e-7,0.000059422637,0.0009902308,0.003817084,0.9802661],"study_design_scores_gemma":[0.0008035628,0.00038028232,0.000015650909,0.022563944,0.00059239304,0.000008867213,0.00091372,0.00002223938,0.00011926345,0.00054667663,0.9737916,0.00024182531],"about_ca_topic_score_codex":0.00005910933,"about_ca_topic_score_gemma":0.000014991684,"teacher_disagreement_score":0.9800243,"about_ca_system_score_codex":0.000052284464,"about_ca_system_score_gemma":0.00016352888,"threshold_uncertainty_score":0.9999786},"labels":[],"label_agreement":null},{"id":"W4413423902","doi":"10.36497/jri.v45i3.693","title":"Non-Genetic Risk Factors for First-Line Anti-Tuberculosis Drug-Induced Liver Injury in Active Pulmonary Tuberculosis Patients: A Systematic Review and Meta-Analysis","year":2025,"lang":"en","type":"article","venue":"Jurnal Respirologi Indonesia","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Pulmonary tuberculosis; Meta-analysis; Medicine; Tuberculosis; Drug; First line; Liver injury; Internal medicine; Intensive care medicine; Pharmacology; Pathology","score_opus":0.07362979602816781,"score_gpt":0.37839420869359514,"score_spread":0.3047644126654273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413423902","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9845707,0.007218361,0.00014786755,0.0012963947,0.00026207892,0.005886662,0.00044174722,0.00006395696,0.00011226242],"genre_scores_gemma":[0.98519796,0.008882014,0.000042120897,0.0034328124,0.000040429688,0.0022567299,0.000047394507,0.00003451113,0.00006600364],"study_design_codex":"observational","study_design_gemma":"meta_analysis","domain_scores_codex":[0.994669,0.0019282359,0.0014982991,0.0008933796,0.00030845474,0.00070262887],"domain_scores_gemma":[0.9962177,0.0018497104,0.00085317995,0.0005100822,0.0003290393,0.00024023419],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0020186792,0.00066096586,0.0028819619,0.0011161187,0.0006216923,0.00005098328,0.00045040628,0.00078773726,0.00012500558],"category_scores_gemma":[0.0009039977,0.00051597203,0.001244467,0.0019136869,0.00013374886,0.000282271,0.00018734719,0.001486114,0.000016524047],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020891945,0.0036586558,0.6993435,0.092744045,0.1919637,0.000089382746,0.0013786284,0.0019854417,0.0020929684,0.00008600843,0.00047213284,0.0040963264],"study_design_scores_gemma":[0.0017291679,0.00050171267,0.47923207,0.000661328,0.503692,0.000008910941,0.000100318706,0.0039951107,0.008631046,0.00029325855,0.00026372614,0.0008913452],"about_ca_topic_score_codex":0.00041083407,"about_ca_topic_score_gemma":0.00033460735,"teacher_disagreement_score":0.31172827,"about_ca_system_score_codex":0.00027229995,"about_ca_system_score_gemma":0.00008736776,"threshold_uncertainty_score":0.9997292},"labels":[],"label_agreement":null},{"id":"W4413596049","doi":"10.1186/s10020-025-01324-0","title":"CpG-oligodeoxynucleotides challenged macrophages ameliorate acetaminophen induced liver injury by activating TLR9/IRG1/itaconate metabolic pathway","year":2025,"lang":"en","type":"article","venue":"Molecular Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"CpG Oligodeoxynucleotide; TLR9; Cytotoxicity; Pharmacology; Acetaminophen; In vivo; Liver injury; Immune system; Apoptosis; In vitro; Biology; Cancer research; Immunology; Biochemistry; Gene expression; Gene; DNA methylation","score_opus":0.07205983458167249,"score_gpt":0.39976256623268785,"score_spread":0.3277027316510154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413596049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97152084,0.0086415475,0.0015443428,0.004934542,0.001921213,0.001137238,0.000058895424,0.00032361853,0.009917784],"genre_scores_gemma":[0.9880995,0.0014341206,0.00012491015,0.008353301,0.00031408976,0.00029061493,0.00005432615,0.00006664856,0.0012624562],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9960205,0.0012893284,0.0007222435,0.0007696071,0.00039026793,0.0008080411],"domain_scores_gemma":[0.9983134,0.0003133271,0.00034004851,0.0004862118,0.0002282774,0.0003186906],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00151618,0.000578969,0.00081911765,0.0004625354,0.0005694138,0.000035699046,0.0005144078,0.00073860097,0.0008179882],"category_scores_gemma":[0.00050190225,0.00053557206,0.00016470601,0.0009267012,0.0003480321,0.00022547788,0.00022306522,0.0020167285,0.00014841814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022618697,0.0001932267,0.00010922699,0.00013490827,0.00043097214,0.00013306522,0.000982733,0.000030257801,0.87803197,0.0022113337,0.0012675282,0.116248615],"study_design_scores_gemma":[0.0023807872,0.00024926514,0.0013174608,0.00014969175,0.00024672184,0.000012340472,0.0003149501,0.0008950762,0.87797743,0.0012486564,0.114766665,0.00044097612],"about_ca_topic_score_codex":0.00024892646,"about_ca_topic_score_gemma":0.000016799844,"teacher_disagreement_score":0.11580764,"about_ca_system_score_codex":0.00012960336,"about_ca_system_score_gemma":0.00015073606,"threshold_uncertainty_score":0.9997096},"labels":[],"label_agreement":null},{"id":"W4413602743","doi":"10.64628/aam.wdn4n4dag","title":"Acetaminophen overdose is a leading cause of liver injury, but it is largely preventable","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Waterloo","funders":"","keywords":"Acetaminophen; Liver injury; Medicine; acetaminophen overdose; Intensive care medicine; Medical emergency; Emergency medicine; Internal medicine; Anesthesia; Acetylcysteine; Chemistry","score_opus":0.3484099334468912,"score_gpt":0.4787105224012477,"score_spread":0.13030058895435648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413602743","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9629432,0.00061851216,0.00074965734,0.0038094383,0.0056754253,0.0030987223,0.0025847643,0.00060645357,0.019913804],"genre_scores_gemma":[0.8498873,0.0028288763,0.00042518816,0.007733567,0.00058305543,0.00030113387,0.000118558215,0.00012714513,0.13799517],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99620795,0.0006878726,0.00091075577,0.0009791828,0.00041675413,0.000797509],"domain_scores_gemma":[0.99780905,0.0003523415,0.00061217,0.0007136844,0.00021999465,0.00029273384],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0015326289,0.0006249229,0.0009135122,0.00040313907,0.00033170488,0.00006002434,0.000707894,0.0021824318,0.009266553],"category_scores_gemma":[0.0001223908,0.0006659218,0.00044979248,0.0003822215,0.0001860066,0.00022154521,0.0013896814,0.0033639215,0.0021997846],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001481888,0.0021602416,0.018163953,0.0058496115,0.005411078,0.0002569626,0.022482691,0.0010644455,0.16091739,0.0013418613,0.75778884,0.023081038],"study_design_scores_gemma":[0.0013910598,0.00022741473,0.0012423301,0.0003546723,0.0009565254,0.000021878992,0.00035607483,0.0076919454,0.827171,0.004497294,0.15498462,0.0011051695],"about_ca_topic_score_codex":0.0020895752,"about_ca_topic_score_gemma":0.00029525047,"teacher_disagreement_score":0.6662536,"about_ca_system_score_codex":0.0003022291,"about_ca_system_score_gemma":0.00036508834,"threshold_uncertainty_score":0.9995792},"labels":[],"label_agreement":null},{"id":"W4413603334","doi":"10.64628/aap.u3end6a3m","title":"La surdose d’acétaminophène est l’une des principales causes de lésions hépatiques. Voici comment l’éviter","year":2023,"lang":"fr","type":"preprint","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Waterloo","funders":"","keywords":"Philosophy; Art","score_opus":0.2684306080277253,"score_gpt":0.4611386664706926,"score_spread":0.19270805844296734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413603334","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93768376,0.0009902036,0.0036232467,0.021077175,0.0064414004,0.003311871,0.00086863514,0.0012178039,0.024785912],"genre_scores_gemma":[0.9497865,0.012891727,0.0023142959,0.0063144425,0.001126529,0.0012958115,0.0005145716,0.00023935034,0.0255168],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.98926073,0.005535752,0.0014677221,0.0014035526,0.00046439611,0.0018678379],"domain_scores_gemma":[0.99378824,0.003237867,0.00064980856,0.0009294985,0.0003832115,0.0010113701],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"category_scores_codex":[0.004706798,0.0012817687,0.0012206854,0.0005115699,0.0015742773,0.00022780926,0.00097147626,0.004222223,0.0032265743],"category_scores_gemma":[0.0005311832,0.0013452853,0.00062172575,0.00076400646,0.0016530247,0.00031699418,0.0015708912,0.0070454758,0.0026866875],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022315627,0.014144317,0.43564087,0.0097281765,0.0071588787,0.003770087,0.059419107,0.038259123,0.09082933,0.14767694,0.046916563,0.14422505],"study_design_scores_gemma":[0.0027873549,0.00046519737,0.09069265,0.001079751,0.0014068945,0.00031139568,0.0015718928,0.011318171,0.114880264,0.021909257,0.7514603,0.0021168834],"about_ca_topic_score_codex":0.009537904,"about_ca_topic_score_gemma":0.012199541,"teacher_disagreement_score":0.7045437,"about_ca_system_score_codex":0.001976061,"about_ca_system_score_gemma":0.0008448468,"threshold_uncertainty_score":0.99999344},"labels":[],"label_agreement":null},{"id":"W4413838790","doi":"10.1080/17474124.2025.2551265","title":"What’s new in the critical care management of acute liver failure: a focus on global accessibility","year":2025,"lang":"en","type":"review","venue":"Expert Review of Gastroenterology & Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta Hospital; University of Alberta","funders":"","keywords":"Medicine; Intensive care medicine; Liver failure; Focus (optics); Liver transplantation; Critical pathways; Internal medicine; Process management; Transplantation","score_opus":0.1040206433195438,"score_gpt":0.49486433096523263,"score_spread":0.39084368764568883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413838790","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015445816,0.9878838,0.00011539125,0.0042536333,0.003071337,0.0034740658,0.00021124844,0.000035903675,0.00080015714],"genre_scores_gemma":[0.0018645093,0.989636,0.00032803754,0.006863471,0.0001696851,0.0009548096,0.00012508211,0.000025639141,0.00003277252],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9884979,0.007106945,0.0021373115,0.0010577613,0.00031726345,0.0008828218],"domain_scores_gemma":[0.99676865,0.0009191542,0.000882683,0.0010826937,0.00017227758,0.00017456351],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0015107512,0.00083495333,0.0039981985,0.00027968705,0.0001307976,0.000018029628,0.0017177151,0.0013286694,0.00042377473],"category_scores_gemma":[0.00015755912,0.0006144161,0.0011874442,0.0007178139,0.0006824352,0.00018178322,0.0004887102,0.0020321654,0.00004705799],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005558352,0.00072371116,0.0006013351,0.15063062,0.0011383746,0.00041588684,0.0003603248,2.3684794e-7,8.9330143e-7,0.0027783853,0.00657252,0.8362219],"study_design_scores_gemma":[0.0012942924,0.0012665971,0.00008348721,0.06915054,0.0041557555,0.00048688095,0.00021210338,0.0000045832353,0.000026716418,0.00048386783,0.92247236,0.0003627995],"about_ca_topic_score_codex":0.00010836565,"about_ca_topic_score_gemma":0.00034584047,"teacher_disagreement_score":0.9158999,"about_ca_system_score_codex":0.00038265763,"about_ca_system_score_gemma":0.00042096333,"threshold_uncertainty_score":0.9999678},"labels":[],"label_agreement":null},{"id":"W4414075605","doi":"10.1016/j.toxlet.2025.07.226","title":"P04-09 Changes in miRNA levels as biomarkers for drug-induced liver injury in human plasma","year":2025,"lang":"en","type":"article","venue":"Toxicology Letters","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"PROTO Manufacturing (Canada)","funders":"","keywords":"Liver injury; microRNA; Alanine aminotransferase; Cohort; Drug; Therapeutic drug monitoring; Incidence (geometry); Alanine transaminase; Real-time polymerase chain reaction","score_opus":0.11800468772681943,"score_gpt":0.427736065464604,"score_spread":0.3097313777377846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414075605","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9693462,0.00006415843,0.000049861697,0.022280892,0.0026080608,0.0022921208,0.00005024467,0.00014016275,0.003168274],"genre_scores_gemma":[0.97349054,0.000042023657,0.00013922459,0.024004653,0.00020840699,0.001128287,0.000028382,0.000040279872,0.00091817917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99629146,0.0010924593,0.0006424674,0.00077668484,0.00013742116,0.0010595333],"domain_scores_gemma":[0.9984901,0.0007837934,0.00020948343,0.0003074359,0.000052955278,0.00015624698],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0017254391,0.0004457617,0.00061302487,0.0012906748,0.0003938172,0.000029952653,0.00050903123,0.001032967,0.00047620106],"category_scores_gemma":[0.00020568605,0.0005144597,0.00015205568,0.0008244404,0.00030060485,0.00018169625,0.00015250985,0.0015282051,0.000114971146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009975707,0.0005053421,0.0101068225,0.00016240947,0.00021475225,0.00011210993,0.0012132981,0.00010771822,0.9524364,0.0016760507,0.006647792,0.025819719],"study_design_scores_gemma":[0.007072972,0.00041917016,0.02482689,0.0001240307,0.00012161761,0.000019922258,0.00026805943,0.0016244812,0.9029346,0.0016676605,0.060130265,0.0007903084],"about_ca_topic_score_codex":0.0004050188,"about_ca_topic_score_gemma":0.0048839776,"teacher_disagreement_score":0.05348247,"about_ca_system_score_codex":0.00059747713,"about_ca_system_score_gemma":0.00016106888,"threshold_uncertainty_score":0.9997307},"labels":[],"label_agreement":null},{"id":"W4414338200","doi":"10.1007/s00210-025-04638-2","title":"Retraction Note: The crucial role of oxidative stress in non-alcoholic fatty liver disease-induced male reproductive toxicity: the ameliorative effects of Iranian indigenous probiotics","year":2025,"lang":"en","type":"article","venue":"Naunyn-Schmiedeberg s Archives of Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":true,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Oxidative stress; Indigenous; Fatty liver; Oxidative damage","score_opus":0.029359624476693106,"score_gpt":0.3670374626388468,"score_spread":0.3376778381621537,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414338200","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883825,0.0008934485,0.00047870062,0.0010911191,0.0020772964,0.0044405535,0.00015261803,0.000034035038,0.0024497008],"genre_scores_gemma":[0.9975667,0.0006550773,0.00019788886,0.0006168712,0.00037999765,0.00035908888,0.000021038988,0.00003149184,0.00017182135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99443007,0.0029381893,0.0010165988,0.0006919459,0.00029581768,0.0006273566],"domain_scores_gemma":[0.9951944,0.0029427418,0.0010019031,0.00046516967,0.0002530755,0.00014270635],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0010589844,0.0004478829,0.0008241997,0.0005877415,0.00046972558,0.000012768543,0.0008380976,0.0005685181,0.000098136516],"category_scores_gemma":[0.00057120767,0.00034489244,0.00029092008,0.0011214517,0.0011762892,0.00020785576,0.00031300602,0.002460518,0.0000070510623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005381558,0.0018799774,0.007142979,0.0007272611,0.0007164919,0.000025529722,0.023217695,0.0025304689,0.9298683,0.00078706193,0.00013121529,0.027591487],"study_design_scores_gemma":[0.0023668248,0.0005956894,0.051993616,0.00017399047,0.0005753272,0.000005614107,0.00081268314,0.0036887014,0.9371729,0.0018047427,0.0005449617,0.00026496593],"about_ca_topic_score_codex":0.0006618071,"about_ca_topic_score_gemma":0.0005172161,"teacher_disagreement_score":0.04485064,"about_ca_system_score_codex":0.00013905276,"about_ca_system_score_gemma":0.0006535464,"threshold_uncertainty_score":0.9999003},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"high"},{"model":"gpt","categories":["research_integrity"],"domain":null,"study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"high"}],"label_agreement":"split"},{"id":"W4414709653","doi":"10.26538/tjnpr/v9i9.9","title":"Chitosan Nanoparticles as a Therapeutic Agent for Mitigating Paracetamol-Induced Liver Damage in White Male Albino Rats","year":2025,"lang":"en","type":"article","venue":"Tropical Journal of Natural Product Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Trent University; Nottingham Trent University; University of Baghdad","keywords":"Comet assay; Chitosan; DNA damage; Antioxidant; Infiltration (HVAC); Liver damage; Therapeutic effect; Distilled water","score_opus":0.22479981781196046,"score_gpt":0.5029554399393847,"score_spread":0.2781556221274243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414709653","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9842073,0.0023083512,0.000021429561,0.010191462,0.0011858451,0.0011997841,0.0000036580852,0.00001821159,0.0008639991],"genre_scores_gemma":[0.9968484,0.00021786634,0.0003302757,0.0007351104,0.0005870962,0.0000626166,0.0000022390623,0.00001696544,0.0011994019],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9956483,0.0020470358,0.0006907135,0.0003639301,0.00048105093,0.00076893356],"domain_scores_gemma":[0.9981423,0.00087188446,0.00019284923,0.00021191445,0.00040506606,0.00017601221],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0023263264,0.00020591945,0.00040602955,0.0005049494,0.000410934,0.00008189526,0.0004862937,0.00026794514,0.00016791577],"category_scores_gemma":[0.0012219617,0.00016692329,0.00018175937,0.00083310634,0.00022917906,0.00028241446,0.000121466524,0.00365084,0.000027304555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002027694,0.00045069034,0.018599477,0.00018459356,0.00015057066,0.00014017262,0.0006142531,0.00009313827,0.9111237,0.0014991413,0.00056476734,0.06455179],"study_design_scores_gemma":[0.0023980897,0.0006584974,0.066824704,0.00015965645,0.000059808528,0.00013098297,0.00026636012,0.001833839,0.91716474,0.002650489,0.0076589477,0.00019389993],"about_ca_topic_score_codex":0.000028618391,"about_ca_topic_score_gemma":0.000058949085,"teacher_disagreement_score":0.0643579,"about_ca_system_score_codex":0.00018868594,"about_ca_system_score_gemma":0.00038411806,"threshold_uncertainty_score":0.99864775},"labels":[],"label_agreement":null},{"id":"W4416097560","doi":"10.1111/his.70027","title":"The validation of histological criteria from the IAIH‐PG to distinguish AIH from drug‐induced liver injury","year":2025,"lang":"en","type":"article","venue":"Histopathology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Hamilton Health Sciences","funders":"Ministry of Science and Technology of the People's Republic of China","keywords":"Liver injury; Diagnostic accuracy; Biopsy; Anatomical pathology; Histology","score_opus":0.10964913522993824,"score_gpt":0.4244642235339365,"score_spread":0.31481508830399824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416097560","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9782531,0.0008112786,0.00047737345,0.0055671846,0.007038892,0.0006644763,0.00022302102,0.00010068177,0.0068639405],"genre_scores_gemma":[0.99317974,0.000089031346,0.00021738965,0.0045776204,0.00045221313,0.00017324557,0.000061219194,0.000015493635,0.0012340317],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963786,0.0020735029,0.0005537779,0.00047565752,0.00013970365,0.0003787794],"domain_scores_gemma":[0.9970024,0.0019818537,0.00025748942,0.000501237,0.00016281189,0.000094165334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001235977,0.00023913282,0.00036724468,0.0000852798,0.0008936205,0.000025884701,0.00063975924,0.0004805101,0.000591511],"category_scores_gemma":[0.0011539246,0.00017075028,0.00013492104,0.000292188,0.00040730316,0.000058332047,0.0002471066,0.0009871955,0.00016928921],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040319893,0.00054118235,0.020340934,0.000040185205,0.00010454541,0.000104309496,0.008442729,0.000028849792,0.7980788,0.012595641,0.0828318,0.07285905],"study_design_scores_gemma":[0.0008825755,0.00033310926,0.08076114,0.000041999672,0.0002930403,0.00001117919,0.00046594083,0.0003413271,0.1806341,0.0115409,0.72434044,0.00035426382],"about_ca_topic_score_codex":0.0011153647,"about_ca_topic_score_gemma":0.0007555457,"teacher_disagreement_score":0.64150864,"about_ca_system_score_codex":0.0002823811,"about_ca_system_score_gemma":0.00011922951,"threshold_uncertainty_score":0.69629943},"labels":[],"label_agreement":null},{"id":"W4416148255","doi":"10.4212/cjhp.3827","title":"Pharmacist-Led Assessment of Drug-Induced Liver Injury in Hospitalized Patients","year":2025,"lang":"en","type":"article","venue":"The Canadian Journal of Hospital Pharmacy","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"","keywords":"Liver injury; Liver function; MEDLINE; Liver function tests; Function (biology)","score_opus":0.05768897958736388,"score_gpt":0.4129036865372136,"score_spread":0.3552147069498497,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416148255","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98385984,0.00032354335,0.00001698909,0.00257891,0.0065403567,0.00096873695,0.00007840572,0.000013998985,0.005619205],"genre_scores_gemma":[0.99783534,0.00020807557,0.00005770542,0.0013827009,0.00019950328,0.00003406876,0.0000077722825,0.000025394733,0.0002494183],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.996855,0.00092877273,0.0010538333,0.00023769311,0.0003195291,0.0006051514],"domain_scores_gemma":[0.99781233,0.00023368926,0.00068425597,0.00022774532,0.0005598308,0.00048214567],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0020009424,0.00031682322,0.00054031657,0.0007318163,0.00042268762,0.00005460349,0.0008273972,0.00017952941,0.00051348313],"category_scores_gemma":[0.00020228921,0.00026653166,0.0002794672,0.0008080232,0.00027951336,0.00040256162,0.00006609164,0.0020197493,0.000022047672],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00095396925,0.0016643952,0.89886373,0.00025867685,0.001012391,0.00031855507,0.0051727667,0.00042993628,0.011752756,0.002056001,0.016172495,0.061344344],"study_design_scores_gemma":[0.032554127,0.0016669597,0.51391864,0.00058185094,0.0011989864,0.00004192105,0.0005722888,0.0061675804,0.24441892,0.004989557,0.19231719,0.0015719631],"about_ca_topic_score_codex":0.0066601792,"about_ca_topic_score_gemma":0.004324232,"teacher_disagreement_score":0.38494506,"about_ca_system_score_codex":0.000724815,"about_ca_system_score_gemma":0.0021562518,"threshold_uncertainty_score":0.99997866},"labels":[],"label_agreement":null},{"id":"W4416230058","doi":"10.1016/j.amjmed.2025.11.007","title":"Updates for healthcare providers: Myths about acetaminophen","year":2025,"lang":"en","type":"article","venue":"The American Journal of Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Population Health Research Institute","funders":"U.S. Food and Drug Administration; Amgen","keywords":"Acetaminophen; Health care; Mythology; Opioid; MEDLINE; Over-the-counter","score_opus":0.10507986635067747,"score_gpt":0.47393882924976855,"score_spread":0.3688589628990911,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416230058","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.63516366,0.0043694354,0.004810439,0.34862906,0.003489995,0.0011057343,0.00002079021,0.00004722289,0.002363655],"genre_scores_gemma":[0.9718647,0.00082204386,0.00029983572,0.025293786,0.0010542509,0.00003337558,0.0000030575063,0.0000125322185,0.00061644515],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99820876,0.0006403197,0.00054533186,0.00013097774,0.00017375812,0.00030084126],"domain_scores_gemma":[0.9977175,0.000952253,0.00071766885,0.00016759375,0.00029893,0.00014603161],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0024549328,0.00015526837,0.0004980978,0.00018897613,0.0003177701,0.000009815731,0.00039520205,0.00008406921,0.000085036],"category_scores_gemma":[0.00046673365,0.00009410073,0.00011398842,0.00040439132,0.00081537024,0.0000902892,0.000033311455,0.0009529937,0.0000075058247],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0038208128,0.00016670857,0.0022482502,0.0002244324,0.000691085,0.00002175889,0.0046067205,0.0001553537,0.031847034,0.0036752475,0.049279664,0.9032629],"study_design_scores_gemma":[0.007734504,0.0052489787,0.0057880464,0.00060916215,0.00096820923,0.00031682156,0.012456334,0.0010625438,0.030952677,0.0148595935,0.91968405,0.00031906323],"about_ca_topic_score_codex":0.000084200954,"about_ca_topic_score_gemma":0.000014734265,"teacher_disagreement_score":0.90294385,"about_ca_system_score_codex":0.00009809142,"about_ca_system_score_gemma":0.00022726617,"threshold_uncertainty_score":0.41403362},"labels":[],"label_agreement":null},{"id":"W4416333924","doi":"10.1038/s41598-025-24262-7","title":"Identifying high-risk drugs and demographic patterns in drug-induced liver injury from FAERS and CVARD analyses","year":2025,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Adverse Event Reporting System; Drug; Adverse effect; Liver injury; MEDLINE; Pharmacoepidemiology; Drug reaction","score_opus":0.0946448378303666,"score_gpt":0.4182747378196011,"score_spread":0.3236298999892345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416333924","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900903,0.00066410005,0.00012555567,0.00016637107,0.007819858,0.00057122257,0.000036522542,0.000091707916,0.00043435203],"genre_scores_gemma":[0.9984996,0.00042404307,0.000114138296,0.00023224394,0.00007481327,0.000062629784,0.00004293313,0.000014837837,0.0005347735],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969017,0.0006739542,0.00065553386,0.0010646322,0.00026182598,0.0004423515],"domain_scores_gemma":[0.9986664,0.00026868092,0.00035203266,0.00043052668,0.000091643,0.00019070857],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002686419,0.00026623855,0.0003713867,0.00087888754,0.000804665,0.00026998404,0.00014474957,0.000344072,0.00015305221],"category_scores_gemma":[0.00015697366,0.00026983296,0.000094321826,0.0010292422,0.00032496813,0.00035306957,0.0002075731,0.000959252,0.000009790803],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000101731464,0.0001474875,0.7101244,0.00013583532,0.00024926537,0.00037588374,0.003636908,0.00003400183,0.2084148,0.0001180099,0.001163646,0.07549808],"study_design_scores_gemma":[0.0014567684,0.000049409722,0.37084007,0.00030930393,0.00061107567,0.00005190133,0.0018222964,0.0018904578,0.5722038,0.035360698,0.014601479,0.0008027221],"about_ca_topic_score_codex":0.0067311726,"about_ca_topic_score_gemma":0.002932494,"teacher_disagreement_score":0.36378902,"about_ca_system_score_codex":0.00007448133,"about_ca_system_score_gemma":0.00010059061,"threshold_uncertainty_score":0.9999754},"labels":[],"label_agreement":null},{"id":"W4416781717","doi":"10.1186/s40360-025-01051-6","title":"Epidemiology of drug-related liver injury among the elderly: a systematic review and meta-analysis of incidence, and risk factors","year":2025,"lang":"en","type":"article","venue":"BMC Pharmacology and Toxicology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Incidence (geometry); Epidemiology; Diabetes mellitus; Disease; Risk factor; Population; Chronic liver disease; Liver injury","score_opus":0.126737628594673,"score_gpt":0.4314753493685676,"score_spread":0.3047377207738946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416781717","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89069027,0.10510469,0.000117741154,0.0007595732,0.00037930146,0.0025230662,0.00016680313,0.00004112813,0.00021741005],"genre_scores_gemma":[0.9676345,0.028838709,0.0000610447,0.0024480198,0.000013723446,0.00046695655,0.0000111766085,0.000013543523,0.0005123063],"study_design_codex":"observational","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9880574,0.0091684675,0.0015691217,0.00062906725,0.00009517191,0.00048076964],"domain_scores_gemma":[0.98885685,0.009105828,0.0013645927,0.00031989574,0.00017682742,0.00017601493],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0058060624,0.0004340805,0.0035734111,0.00066024374,0.00045286896,0.0000038713047,0.00034133918,0.00083405606,0.00068771804],"category_scores_gemma":[0.0011686711,0.0002952687,0.00053838064,0.0011072858,0.002126967,0.00013904696,0.0003187761,0.0013434883,0.00000306632],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051292597,0.0005412033,0.68306494,0.057569668,0.24410605,0.000013426106,0.0018131707,0.00032097212,0.0028245696,0.007973847,0.00095247285,0.00030677498],"study_design_scores_gemma":[0.0012102328,0.0004654268,0.11804131,0.00020529015,0.8662038,0.000032171312,0.0002369255,0.003951808,0.006786752,0.00225243,0.00021037993,0.00040351067],"about_ca_topic_score_codex":0.00034224737,"about_ca_topic_score_gemma":0.0005383202,"teacher_disagreement_score":0.62209773,"about_ca_system_score_codex":0.000037283884,"about_ca_system_score_gemma":0.00010837323,"threshold_uncertainty_score":0.99994993},"labels":[],"label_agreement":null},{"id":"W4417060527","doi":"10.3138/canlivj-2025-0039","title":"Drug-induced liver injury secondary to anakinra in a patient with systemic juvenile idiopathic arthritis—Case report and literature overview","year":2025,"lang":"en","type":"article","venue":"Canadian Liver Journal","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario; Royal University Hospital; University of Ottawa; University of Saskatchewan","funders":"","keywords":"Anakinra; Liver injury; Liver biopsy; Liver enzyme; Biopsy; Liver function; Liver function tests","score_opus":0.038066888729552086,"score_gpt":0.3293136844839752,"score_spread":0.2912467957544231,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417060527","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97937584,0.016185883,0.000017192282,0.0009882216,0.0013206352,0.00080296927,0.00009932926,0.000026039821,0.0011839103],"genre_scores_gemma":[0.99356174,0.001305434,0.000058176665,0.0044791894,0.00021171247,0.00007277401,0.0000075312405,0.000022731134,0.0002807283],"study_design_codex":"case_report","study_design_gemma":"case_report","domain_scores_codex":[0.9974603,0.00075038045,0.0006288124,0.00041489906,0.00014582886,0.00059977773],"domain_scores_gemma":[0.9983523,0.00005527622,0.00022167843,0.00021837963,0.0002143939,0.0009379776],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0012868245,0.00028898785,0.00043786428,0.00088483066,0.0006218044,0.00015739261,0.00015345118,0.0004305061,0.00020847011],"category_scores_gemma":[0.00009145364,0.0002844414,0.00007624168,0.0007529838,0.000054897366,0.00033108794,0.000052565658,0.0026319087,0.000026138556],"study_design_candidate":"case_report","study_design_consensus":"case_report","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033028264,0.00012226652,0.008879685,0.0005716472,0.00019566725,0.7037867,0.0097617,0.00010072074,0.0020551977,0.00044523826,0.0050337324,0.26871717],"study_design_scores_gemma":[0.0032362766,0.0006937229,0.003975933,0.006148458,0.000183909,0.8677709,0.002054877,0.0007242832,0.005459134,0.0003730375,0.10836504,0.0010144312],"about_ca_topic_score_codex":0.012137609,"about_ca_topic_score_gemma":0.16309749,"teacher_disagreement_score":0.26770276,"about_ca_system_score_codex":0.00082347187,"about_ca_system_score_gemma":0.0017322416,"threshold_uncertainty_score":0.9999608},"labels":[],"label_agreement":null},{"id":"W4417469088","doi":"10.52609/jmlph.v6i1.223","title":"Methotrexate-Induced Hepatotoxicity in a Patient with a History of Alcohol Abuse: Case Report","year":2025,"lang":"en","type":"article","venue":"The Journal of Medicine Law & Public Health","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Rheumatoid arthritis; Alcohol abuse; Alcohol; Adverse effect; Alcohol and health","score_opus":0.22016097114322858,"score_gpt":0.4570908172309548,"score_spread":0.23692984608772621,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417469088","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95143723,0.0019268127,0.0006522052,0.030548733,0.0017240199,0.00086511247,0.00000484422,0.000025570404,0.012815484],"genre_scores_gemma":[0.9876186,0.00046617334,0.0001441919,0.011309605,0.00019271635,0.00002126456,0.00000235304,0.00001509957,0.00022999952],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99342257,0.0036771696,0.0017013309,0.0002041468,0.00047380364,0.00052099355],"domain_scores_gemma":[0.9961004,0.0009026857,0.0017643794,0.000368784,0.00047524917,0.00038848747],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.015421027,0.00024094133,0.0008335187,0.00046578574,0.00020468207,0.000004856005,0.00032215717,0.00026059285,0.00016557623],"category_scores_gemma":[0.00053998036,0.0001496141,0.00009017752,0.0007248529,0.00049958844,0.00020793357,0.00004402617,0.0022052382,0.0000016085215],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.014872623,0.010222621,0.0232534,0.004496065,0.004350399,0.1395319,0.22589315,0.0017895926,0.07824669,0.0505803,0.09052352,0.35623974],"study_design_scores_gemma":[0.016422378,0.006595557,0.0018518171,0.0012587759,0.0005206313,0.16150412,0.006607396,0.0018545423,0.012930785,0.0018102223,0.7881051,0.0005387072],"about_ca_topic_score_codex":0.0062057995,"about_ca_topic_score_gemma":0.0027585288,"teacher_disagreement_score":0.6975815,"about_ca_system_score_codex":0.0013477388,"about_ca_system_score_gemma":0.0025086359,"threshold_uncertainty_score":0.9580785},"labels":[],"label_agreement":null},{"id":"W44455618","doi":"10.1177/070674370204700409","title":"Hepatic Adverse Reactions Associated with Nefazodone","year":2002,"lang":"en","type":"article","venue":"The Canadian Journal of Psychiatry","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":79,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Nefazodone; Adverse effect; Medicine; Adverse drug reaction; Drug; Internal medicine; Psychiatry","score_opus":0.10012538637992638,"score_gpt":0.34374196084721226,"score_spread":0.24361657446728588,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W44455618","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95160055,0.0007220136,0.000052105544,0.026283437,0.005001826,0.0002875965,0.000032156935,0.000025847316,0.01599448],"genre_scores_gemma":[0.99548554,0.00004756575,0.00017522156,0.002208657,0.0005270609,0.000005847295,0.000001928328,0.000018934203,0.0015292274],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985828,0.0004589418,0.00035831696,0.000096148826,0.00014951092,0.00035428707],"domain_scores_gemma":[0.9986459,0.00014425625,0.00040228182,0.00014855432,0.00015670859,0.0005023157],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009289541,0.000139681,0.0001811322,0.00020374585,0.0009194588,0.00002496765,0.00026642496,0.0002360631,0.0021821198],"category_scores_gemma":[0.00013245239,0.00010053156,0.00011084807,0.00038220757,0.0001999184,0.00015885787,0.00000514193,0.0015084104,0.00015344883],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007454747,0.0015939275,0.6625876,0.00015763746,0.0047879256,0.0007884776,0.016267454,0.014884487,0.0022332994,0.03764496,0.22554825,0.032760527],"study_design_scores_gemma":[0.013227989,0.0025932733,0.2033949,0.00091141346,0.0030290154,0.0048706406,0.0036452306,0.009393212,0.002751774,0.04304627,0.7111852,0.001951058],"about_ca_topic_score_codex":0.0036759384,"about_ca_topic_score_gemma":0.31274343,"teacher_disagreement_score":0.48563695,"about_ca_system_score_codex":0.00024153887,"about_ca_system_score_gemma":0.00076277374,"threshold_uncertainty_score":0.99873},"labels":[],"label_agreement":null},{"id":"W6907937010","doi":"10.25446/oxford.25691937","title":"53584: The sun used to shine","year":2024,"lang":"en","type":"other","venue":"University of Oxford","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Frost (temperature); Receipt; Poetry; Period (music); George (robot); Quarter (Canadian coin)","score_opus":0.12582551652725166,"score_gpt":0.37765803172591655,"score_spread":0.2518325151986649,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6907937010","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005929764,0.00038553533,0.00033801017,0.0036358747,0.0022673781,0.00088761025,0.0003304583,0.00029461313,0.98593074],"genre_scores_gemma":[0.03587029,0.00031786578,0.000153612,0.000579578,0.00035140515,0.0000014248036,0.000023724746,0.00013025702,0.96257186],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990922,0.00017650737,0.000104310464,0.00026670206,0.00013221872,0.00022804271],"domain_scores_gemma":[0.9994292,0.00007194823,0.00010812587,0.00024145964,0.000027763968,0.0001214727],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00031274767,0.00019249463,0.000255582,0.00024660135,0.00013191067,0.000009277675,0.00043338235,0.0005997826,0.009411546],"category_scores_gemma":[0.000017593957,0.0001760224,0.00014646897,0.00026555936,0.0001507759,0.00002968373,0.00016758215,0.0008838263,0.0013506699],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013397184,0.000084410734,0.00018900925,0.00020799287,0.00037896226,0.00006172555,0.0020445595,0.000028918977,0.0010093556,0.0017812866,0.98564607,0.00843376],"study_design_scores_gemma":[0.00035517706,0.00006746019,0.00004976638,0.000076454526,0.00020817913,0.000004522069,0.00029197882,0.00005745545,0.0008590402,0.0002450018,0.99760073,0.00018420824],"about_ca_topic_score_codex":0.0006669118,"about_ca_topic_score_gemma":0.0021021727,"teacher_disagreement_score":0.029940529,"about_ca_system_score_codex":0.000070077615,"about_ca_system_score_gemma":0.00006313124,"threshold_uncertainty_score":0.9994269},"labels":[],"label_agreement":null},{"id":"W6929691417","doi":"10.5167/uzh-197429","title":"Global Responses to the \"War on Terror\"","year":2018,"lang":"en","type":"article","venue":"Zurich Open Repository and Archive (University of Zurich)","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Geopolitics; Terrorism; Politics; Power (physics); Privilege (computing); Memoir; Accountability; Perspective (graphical); Foreign policy","score_opus":0.08786202624114141,"score_gpt":0.37904473084056944,"score_spread":0.291182704599428,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6929691417","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9256301,0.00004700985,0.0016219986,0.0024109457,0.00069643336,0.00077005837,0.00011379367,0.000045031957,0.06866464],"genre_scores_gemma":[0.9936601,0.000035745303,0.0009777675,0.0012311308,0.00021721923,0.0000029146652,0.0000051072648,0.000008048155,0.003861954],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99741477,0.0016708352,0.0001393462,0.00036866247,0.00014219253,0.00026420393],"domain_scores_gemma":[0.99883807,0.0004569459,0.00013225967,0.00028212377,0.000079085425,0.00021153502],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.001088701,0.00015985334,0.00020905491,0.00009020667,0.001629128,0.00003196901,0.0007206503,0.000142705,0.000146857],"category_scores_gemma":[0.00006394167,0.00014590479,0.00006772924,0.00030110826,0.00044085455,0.0001898741,0.00055083656,0.00034019558,0.00014860283],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.041988082,0.0028915908,0.17502323,0.00025876795,0.0016610823,0.00093944505,0.06900833,0.0005366862,0.17729263,0.023967026,0.38078493,0.1256482],"study_design_scores_gemma":[0.0017298161,0.0019663484,0.15858501,0.000075296644,0.0001798536,0.00013854566,0.003401937,0.0006700702,0.014532946,0.0022806036,0.81599176,0.00044779648],"about_ca_topic_score_codex":0.0004869085,"about_ca_topic_score_gemma":0.00040398585,"teacher_disagreement_score":0.43520686,"about_ca_system_score_codex":0.00005349637,"about_ca_system_score_gemma":0.000081165286,"threshold_uncertainty_score":0.9996706},"labels":[],"label_agreement":null},{"id":"W6938908124","doi":"10.60692/hv3jn-c4366","title":"Role of polymorphic bile salt export pump (BSEP, ABCB11) transporters in anti-tuberculosis drug-induced liver injury in a Chinese cohort","year":2016,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Bile Salt Export Pump; Odds ratio; Genotype; Liver injury; Genotyping; Logistic regression; Polymorphism (computer science); TaqMan","score_opus":0.04811680129062202,"score_gpt":0.29963976082446087,"score_spread":0.25152295953383885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6938908124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992879,0.0000046081122,0.00012824824,0.00008164124,0.0006104178,0.004234008,0.00023663737,0.00013081117,0.0016946733],"genre_scores_gemma":[0.9976574,0.0000044212184,0.000011746478,0.00018985177,0.000093432514,0.0019560684,0.000019786112,0.000022500513,0.00004480192],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9970379,0.0004279042,0.001415264,0.00029953627,0.00031986262,0.00049953326],"domain_scores_gemma":[0.9987846,0.000041332354,0.00053990906,0.00034230392,0.00012147747,0.00017036327],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015040025,0.00035277643,0.0005837532,0.0009500857,0.00010740711,0.000024764508,0.0002666813,0.0005256013,0.00019662357],"category_scores_gemma":[0.000026838672,0.0002662425,0.00016296025,0.00071356614,0.00007657078,0.0010430515,0.000044390355,0.00046628137,0.000304909],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043457234,0.00003948999,0.9564088,0.00036743918,0.00007648089,0.000013398642,0.028855223,0.00010824489,0.009401329,0.000033434724,0.000012082386,0.0042494917],"study_design_scores_gemma":[0.0043943143,0.000101097205,0.8311146,0.00039374345,0.00006404605,0.00004221534,0.0035220645,0.0026118474,0.1568053,0.0000076250894,0.0004006435,0.00054248486],"about_ca_topic_score_codex":0.0002648285,"about_ca_topic_score_gemma":0.000024718338,"teacher_disagreement_score":0.14740397,"about_ca_system_score_codex":0.0002902383,"about_ca_system_score_gemma":0.000101191916,"threshold_uncertainty_score":0.99997896},"labels":[],"label_agreement":null},{"id":"W6939480231","doi":"10.6084/m9.figshare.28548226.v1","title":"Out-of-hospital assessment and triage of paracetamol (acetaminophen) exposure in the United States and Canada: a consensus guideline","year":2025,"lang":"en","type":"article","venue":"Figshare","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Ingestion; Triage; Guideline; Emergency department; Clinical toxicology; Delphi method; Occupational safety and health; Poison control","score_opus":0.11089993278676159,"score_gpt":0.4172063608021656,"score_spread":0.30630642801540403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6939480231","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9649708,0.00057485106,0.0000031243324,0.0019973777,0.00030962913,0.0008287485,0.030506277,0.000012890224,0.0007963038],"genre_scores_gemma":[0.99414444,0.000065477056,0.00005475448,0.0010194993,0.00002635177,0.00016330648,0.0044332263,0.000005913603,0.00008702359],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986786,0.000466824,0.00040593333,0.00016778936,0.00010881211,0.0001719955],"domain_scores_gemma":[0.9986571,0.0008583899,0.00017568802,0.00012849014,0.0001337857,0.000046542562],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00042450672,0.00013328843,0.00024142812,0.000102457605,0.00009241137,0.000010301216,0.00012412772,0.00017201526,0.0020222405],"category_scores_gemma":[0.00038154313,0.0001080694,0.000026225083,0.00021647057,0.000041383286,0.000029664054,0.000066456974,0.00047251125,0.0000015902192],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010081386,0.001506171,0.07851367,0.0035770335,0.0009938941,0.00031638675,0.010748625,0.0023961149,0.007821083,0.0013404461,0.85394096,0.037837464],"study_design_scores_gemma":[0.008910704,0.00087023096,0.10924415,0.0012474386,0.00028018112,0.0000146894445,0.0062245317,0.020944713,0.03592413,0.0008968977,0.8147748,0.0006675441],"about_ca_topic_score_codex":0.019273877,"about_ca_topic_score_gemma":0.052170735,"teacher_disagreement_score":0.039166193,"about_ca_system_score_codex":0.000051279156,"about_ca_system_score_gemma":0.00033053674,"threshold_uncertainty_score":0.99889004},"labels":[],"label_agreement":null},{"id":"W6939507244","doi":"10.60692/t5ws7-jtg44","title":"Role of polymorphic bile salt export pump (BSEP, ABCB11) transporters in anti-tuberculosis drug-induced liver injury in a Chinese cohort","year":2016,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Bile Salt Export Pump; Odds ratio; Genotype; Liver injury; Genotyping; Logistic regression; Polymorphism (computer science); TaqMan","score_opus":0.04811680129062202,"score_gpt":0.29963976082446087,"score_spread":0.25152295953383885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6939507244","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992879,0.0000046081122,0.00012824824,0.00008164124,0.0006104178,0.004234008,0.00023663737,0.00013081117,0.0016946733],"genre_scores_gemma":[0.9976574,0.0000044212184,0.000011746478,0.00018985177,0.000093432514,0.0019560684,0.000019786112,0.000022500513,0.00004480192],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9970379,0.0004279042,0.001415264,0.00029953627,0.00031986262,0.00049953326],"domain_scores_gemma":[0.9987846,0.000041332354,0.00053990906,0.00034230392,0.00012147747,0.00017036327],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015040025,0.00035277643,0.0005837532,0.0009500857,0.00010740711,0.000024764508,0.0002666813,0.0005256013,0.00019662357],"category_scores_gemma":[0.000026838672,0.0002662425,0.00016296025,0.00071356614,0.00007657078,0.0010430515,0.000044390355,0.00046628137,0.000304909],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043457234,0.00003948999,0.9564088,0.00036743918,0.00007648089,0.000013398642,0.028855223,0.00010824489,0.009401329,0.000033434724,0.000012082386,0.0042494917],"study_design_scores_gemma":[0.0043943143,0.000101097205,0.8311146,0.00039374345,0.00006404605,0.00004221534,0.0035220645,0.0026118474,0.1568053,0.0000076250894,0.0004006435,0.00054248486],"about_ca_topic_score_codex":0.0002648285,"about_ca_topic_score_gemma":0.000024718338,"teacher_disagreement_score":0.14740397,"about_ca_system_score_codex":0.0002902383,"about_ca_system_score_gemma":0.000101191916,"threshold_uncertainty_score":0.99997896},"labels":[],"label_agreement":null},{"id":"W6958298975","doi":"10.6084/m9.figshare.28548226","title":"Out-of-hospital assessment and triage of paracetamol (acetaminophen) exposure in the United States and Canada: a consensus guideline","year":2025,"lang":"en","type":"article","venue":"Figshare","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Ingestion; Triage; Guideline; Emergency department; Clinical toxicology; Delphi method; Occupational safety and health; Poison control","score_opus":0.11089993278676159,"score_gpt":0.4172063608021656,"score_spread":0.30630642801540403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6958298975","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9649708,0.00057485106,0.0000031243324,0.0019973777,0.00030962913,0.0008287485,0.030506277,0.000012890224,0.0007963038],"genre_scores_gemma":[0.99414444,0.000065477056,0.00005475448,0.0010194993,0.00002635177,0.00016330648,0.0044332263,0.000005913603,0.00008702359],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986786,0.000466824,0.00040593333,0.00016778936,0.00010881211,0.0001719955],"domain_scores_gemma":[0.9986571,0.0008583899,0.00017568802,0.00012849014,0.0001337857,0.000046542562],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00042450672,0.00013328843,0.00024142812,0.000102457605,0.00009241137,0.000010301216,0.00012412772,0.00017201526,0.0020222405],"category_scores_gemma":[0.00038154313,0.0001080694,0.000026225083,0.00021647057,0.000041383286,0.000029664054,0.000066456974,0.00047251125,0.0000015902192],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010081386,0.001506171,0.07851367,0.0035770335,0.0009938941,0.00031638675,0.010748625,0.0023961149,0.007821083,0.0013404461,0.85394096,0.037837464],"study_design_scores_gemma":[0.008910704,0.00087023096,0.10924415,0.0012474386,0.00028018112,0.0000146894445,0.0062245317,0.020944713,0.03592413,0.0008968977,0.8147748,0.0006675441],"about_ca_topic_score_codex":0.019273877,"about_ca_topic_score_gemma":0.052170735,"teacher_disagreement_score":0.039166193,"about_ca_system_score_codex":0.000051279156,"about_ca_system_score_gemma":0.00033053674,"threshold_uncertainty_score":0.99889004},"labels":[],"label_agreement":null},{"id":"W6958390679","doi":"10.6084/m9.figshare.2064096","title":"Post-print: The time-course of inflammatory cytokine secretion in a rat model of postoperative pain does not coincide with the onset of mechanical hyperalgesia. DOI: 10.1139/Y07-054","year":2016,"lang":"en","type":"article","venue":"Figshare","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Cytokine; Hyperalgesia; Secretion; Tumor necrosis factor alpha; Rat model; Inflammation; Postoperative pain; Proinflammatory cytokine","score_opus":0.0586282339297229,"score_gpt":0.32765752790399444,"score_spread":0.26902929397427156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6958390679","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94392043,0.000045831817,0.000047844274,0.005431754,0.000050652412,0.0012309427,0.04894227,0.00003246561,0.00029783114],"genre_scores_gemma":[0.9971535,0.000011165468,0.000034685723,0.001018757,0.000039342216,0.0002431155,0.0009745393,0.000021346506,0.000503538],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975722,0.0012766562,0.00043646415,0.00023973103,0.00022078196,0.00025415386],"domain_scores_gemma":[0.99749047,0.0013565475,0.00037381117,0.00030956144,0.00040151144,0.00006810975],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011395576,0.00021923645,0.00033868587,0.00008178769,0.0001289349,0.000006740166,0.00036237363,0.00032496333,0.01997596],"category_scores_gemma":[0.0007088977,0.000101191625,0.00010725039,0.00017580845,0.00012928263,0.00015104172,0.0001200306,0.0005577339,0.00010632306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020574594,0.000231467,0.00019560223,0.00016444619,0.00012477103,0.000010594062,0.0017984785,0.0016163735,0.9845812,0.00022798573,0.004480129,0.004511491],"study_design_scores_gemma":[0.001401659,0.00038379463,0.0006401435,0.00056028354,0.00005250163,0.0000151291415,0.00024446507,0.019594979,0.97302496,0.00021893953,0.0036703353,0.00019278027],"about_ca_topic_score_codex":0.000027451148,"about_ca_topic_score_gemma":0.0002504896,"teacher_disagreement_score":0.053233106,"about_ca_system_score_codex":0.00006168457,"about_ca_system_score_gemma":0.0002706552,"threshold_uncertainty_score":0.9809199},"labels":[],"label_agreement":null},{"id":"W6980391736","doi":"","title":"Canadian Labour Papers on Microfilm - Finding Aid","year":2013,"lang":"en","type":"other","venue":"QSpace (Queen's University Library)","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Microform; Listing (finance); Work (physics); Data collection","score_opus":0.029185465731597506,"score_gpt":0.27392262054355143,"score_spread":0.24473715481195393,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6980391736","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0065241107,0.00004510553,0.0000067439987,0.034788717,0.0019481975,0.0010305224,0.0008579582,0.00072289794,0.95407575],"genre_scores_gemma":[0.020658303,0.0008549343,0.0002453435,0.00389394,0.00052664464,0.000006174775,0.00022885653,0.00034206652,0.9732437],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975051,0.0006069605,0.0001593264,0.0006768877,0.00017791033,0.0008737979],"domain_scores_gemma":[0.99835,0.000119541524,0.0002456969,0.00041185267,0.00002112515,0.0008517405],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000092984985,0.0005626783,0.0004625637,0.001202057,0.00055102305,0.0000717521,0.0006645029,0.0019474656,0.0551618],"category_scores_gemma":[0.000019427884,0.0006652723,0.00020851065,0.0005280198,0.00015395672,0.0003716136,0.00014908414,0.0021265163,0.0043827943],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000086616405,0.00007372855,0.0024906972,0.00010836236,0.00026927548,0.0002968907,0.00017004076,0.000020132245,0.00010398971,0.0053033284,0.98944944,0.0016274845],"study_design_scores_gemma":[0.0007916208,0.00009522081,0.0004897909,0.00012418478,0.000100123,0.0000012461114,0.00020667072,0.000005666828,0.004184641,0.00005123368,0.9932539,0.0006957367],"about_ca_topic_score_codex":0.31230098,"about_ca_topic_score_gemma":0.021670455,"teacher_disagreement_score":0.29063052,"about_ca_system_score_codex":0.000509395,"about_ca_system_score_gemma":0.0006210384,"threshold_uncertainty_score":0.99957985},"labels":[],"label_agreement":null},{"id":"W6996061735","doi":"","title":"Prenatal Origins of Endometriosis Pathology and Pain: Reviewing the Evidence of a Role for Low Testosterone","year":2023,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Endometriosis; Testosterone (patch); Infertility; Estrogen; Pelvic pain; Etiology","score_opus":0.5518087836014485,"score_gpt":0.6200430915775641,"score_spread":0.06823430797611563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6996061735","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96616185,0.0304331,0.0003488436,0.0005100783,0.00063809386,0.0015699038,0.00012625486,0.000029671815,0.00018220062],"genre_scores_gemma":[0.95739335,0.04159312,0.0001074713,0.00045545952,0.00012797513,0.00022775192,0.000006318376,0.000026528634,0.000062056155],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99652123,0.0015444132,0.0009267661,0.00034162178,0.0002890932,0.00037686198],"domain_scores_gemma":[0.99122214,0.006943115,0.0010568333,0.00030946938,0.00032410581,0.00014433556],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008811327,0.0002347827,0.0007903177,0.00066215754,0.00032432086,0.00009434235,0.0012628033,0.00024232244,0.0007734923],"category_scores_gemma":[0.004420664,0.00018524894,0.00019267679,0.0014564468,0.00029193418,0.0008815241,0.000566356,0.0006490756,0.0000055033975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007365202,0.00024327902,0.116122186,0.0019633858,0.00032400936,0.000020920099,0.00085772225,0.00021998733,0.72741187,0.00016301947,0.0019075603,0.15002953],"study_design_scores_gemma":[0.0014152845,0.00015105605,0.06556599,0.0023520472,0.00039594286,0.00005597863,0.00021506584,0.0015013403,0.90209115,0.0033753277,0.022510057,0.0003707818],"about_ca_topic_score_codex":0.00020989556,"about_ca_topic_score_gemma":0.000026493462,"teacher_disagreement_score":0.17467925,"about_ca_system_score_codex":0.000073123905,"about_ca_system_score_gemma":0.000119291624,"threshold_uncertainty_score":0.84691983},"labels":[],"label_agreement":null},{"id":"W6996769874","doi":"","title":"Tetragon Financial Group Limited: Performance Report For Quarter Ended 31 March 2015 - Mergers and Acquisitions (MERGERAC) News","year":2015,"lang":"en","type":"other","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Quarter (Canadian coin); Mergers and acquisitions; Group (periodic table); Financial services","score_opus":0.10010445250060597,"score_gpt":0.4041873339589567,"score_spread":0.3040828814583507,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6996769874","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008797852,0.0014660012,0.0016380833,0.0025803891,0.0092190495,0.0045286324,0.0013274828,0.0007838492,0.9696587],"genre_scores_gemma":[0.014863954,0.0018745776,0.0017766407,0.0028532296,0.0039393744,0.0013790636,0.003037056,0.0004244826,0.9698516],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974233,0.00026710844,0.0006068647,0.00076319533,0.00025344896,0.0006860879],"domain_scores_gemma":[0.9985083,0.00016165676,0.000395249,0.0003915687,0.00014822435,0.00039502123],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011110343,0.00054147345,0.0006144422,0.00048236854,0.00037850134,0.00003761045,0.00022336963,0.0017854722,0.002958177],"category_scores_gemma":[0.00013211626,0.00053059566,0.0001709121,0.0003021978,0.00019478136,0.00017799191,0.00007318061,0.0012529155,0.0002166762],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033944883,0.00023115495,0.00026404104,0.00026029727,0.00018210358,0.000041401912,0.00016997637,0.000011252896,0.0018540986,0.00020329432,0.9895145,0.006928399],"study_design_scores_gemma":[0.0015307585,0.00035242658,0.00014603253,0.000060494138,0.00023921105,0.00011092047,0.00007917896,0.0010850162,0.0009138529,0.00024083436,0.9946011,0.00064020144],"about_ca_topic_score_codex":0.0002283123,"about_ca_topic_score_gemma":0.00077631464,"teacher_disagreement_score":0.006288198,"about_ca_system_score_codex":0.0001359184,"about_ca_system_score_gemma":0.00033115194,"threshold_uncertainty_score":0.99971455},"labels":[],"label_agreement":null},{"id":"W7006852698","doi":"","title":"До питання щодо зарубіжного досвіду формування і розвитку інституту звільнення від відбування покарання на прикладі Канади","year":2022,"lang":"uk","type":"article","venue":"eKNUTSHIR","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Legislation; Staffing; Transparency (behavior); Government (linguistics); Punishment (psychology); Best practice; Focus (optics)","score_opus":0.18111755182000247,"score_gpt":0.44265973939006853,"score_spread":0.2615421875700661,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7006852698","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.73963016,0.013755446,0.00040368573,0.02467634,0.051076278,0.008785188,0.004690331,0.0023886072,0.15459397],"genre_scores_gemma":[0.9168527,0.001693742,0.00026351394,0.016121149,0.0052250074,0.0019023916,0.00086149276,0.0005217727,0.056558207],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.97980046,0.00738828,0.0029866751,0.0032822043,0.0022344408,0.004307933],"domain_scores_gemma":[0.99175835,0.0017537208,0.0017755245,0.0022748471,0.000507356,0.0019301979],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"category_scores_codex":[0.006647438,0.0023983382,0.0024644625,0.001407072,0.007119178,0.00045434176,0.0032303324,0.0026889744,0.053651094],"category_scores_gemma":[0.00054070185,0.0028804846,0.0015922127,0.0032316947,0.0011419195,0.0010616662,0.0026527706,0.01332989,0.007964871],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011094941,0.01546026,0.023469642,0.002789088,0.006741357,0.0047029504,0.025471242,0.014973307,0.14193723,0.03377293,0.5462689,0.17331816],"study_design_scores_gemma":[0.007384039,0.0018377965,0.002405674,0.00012833737,0.0012410177,0.00072542235,0.002511518,0.0073924693,0.04086494,0.006380125,0.9258976,0.0032310395],"about_ca_topic_score_codex":0.0011949586,"about_ca_topic_score_gemma":0.0004971873,"teacher_disagreement_score":0.37962872,"about_ca_system_score_codex":0.002449129,"about_ca_system_score_gemma":0.002517246,"threshold_uncertainty_score":0.99887544},"labels":[],"label_agreement":null},{"id":"W7029052129","doi":"","title":"Home Places: Contemporary Native American Writing from Sun Tracks","year":2022,"lang":"en","type":"article","venue":"Project Muse (Johns Hopkins University)","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Native american; Metis; Ethnography; Narrative","score_opus":0.09680101028259742,"score_gpt":0.33924846835995387,"score_spread":0.24244745807735646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7029052129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.69085675,0.000008370051,0.00017758585,0.00036747698,0.00068138115,0.00084887666,0.0007189228,0.0003442776,0.30599633],"genre_scores_gemma":[0.9936048,0.0045109014,0.000154237,0.001115937,0.00023100091,0.000036001984,0.00017038589,0.000041479045,0.00013524893],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964197,0.0018242396,0.00029408277,0.0006371263,0.00030119158,0.0005236366],"domain_scores_gemma":[0.998454,0.0006462403,0.0003573307,0.00026049322,0.000099100704,0.00018283991],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.00063551386,0.00032654117,0.0004184011,0.0044785063,0.0013149132,0.000036373145,0.0005848313,0.00019572729,0.00073784095],"category_scores_gemma":[0.000052318483,0.000408466,0.00019457436,0.0057752416,0.00028856358,0.00044570782,0.00040671186,0.0019783608,0.000049728897],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.020143464,0.008283126,0.094335504,0.0003979932,0.005250802,0.008390498,0.20967354,0.0042430246,0.009114477,0.009946842,0.011877238,0.6183435],"study_design_scores_gemma":[0.002440259,0.00039901442,0.00040813797,0.000012968701,0.000109281675,0.000019428888,0.010966006,0.0016313578,0.00439815,0.000011649125,0.9791017,0.0005020001],"about_ca_topic_score_codex":0.059254777,"about_ca_topic_score_gemma":0.0033973015,"teacher_disagreement_score":0.9672245,"about_ca_system_score_codex":0.00064792926,"about_ca_system_score_gemma":0.0006009702,"threshold_uncertainty_score":0.9999852},"labels":[],"label_agreement":null},{"id":"W7031283143","doi":"","title":"Acknowledgments","year":2017,"lang":"en","type":"book-chapter","venue":"OpenEdition (OpenEdition)","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Social work; Work (physics); Social research","score_opus":0.1449450477496679,"score_gpt":0.3960564839362526,"score_spread":0.2511114361865847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7031283143","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00019466491,0.00054833456,0.00019166383,0.0077274037,0.013294323,0.001889045,0.0015039587,0.00031015265,0.97434044],"genre_scores_gemma":[0.03398406,0.0017806165,0.00016982983,0.023483481,0.004738029,0.00062962406,0.0034430875,0.0001932525,0.93157804],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963194,0.00027669364,0.00090897037,0.001104832,0.0006498879,0.0007402089],"domain_scores_gemma":[0.99645656,0.00025164505,0.0011353883,0.0010218895,0.0005549212,0.0005796197],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0011533836,0.0009213117,0.0008940864,0.0003977333,0.0021359134,0.00029983703,0.0010989885,0.0024833581,0.051561993],"category_scores_gemma":[0.00017944945,0.0010241306,0.00046660873,0.00004829204,0.00052248506,0.005595679,0.00038972276,0.002945186,0.034685146],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007234059,0.0005909992,0.000053283737,0.00047099596,0.0011913137,0.00045092814,0.00018543194,0.000074545096,0.0021063488,0.67540514,0.20218892,0.1165587],"study_design_scores_gemma":[0.0017530868,0.00021302664,0.00031388327,0.0003642622,0.00040619043,0.00008291918,0.000010319311,0.00007329809,0.0066589173,0.030934952,0.9581283,0.0010608695],"about_ca_topic_score_codex":0.00002241846,"about_ca_topic_score_gemma":0.00068539043,"teacher_disagreement_score":0.75593936,"about_ca_system_score_codex":0.0005025868,"about_ca_system_score_gemma":0.00034672662,"threshold_uncertainty_score":0.9993551},"labels":[],"label_agreement":null},{"id":"W7034208822","doi":"","title":"TerraForm Power Reports Third Quarter 2017 Results | Phoenix Arizona Business News - Phoenix Real Estate News - Consumer News","year":2017,"lang":"en","type":"other","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Phoenix; Quarter (Canadian coin); Real estate; Power (physics); News media; News analytics; News bureau","score_opus":0.09088147127186516,"score_gpt":0.3911187899064404,"score_spread":0.30023731863457526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7034208822","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0027398912,0.0002479098,0.00014899106,0.0020269528,0.015410572,0.0028717443,0.00070841674,0.0011500808,0.97469544],"genre_scores_gemma":[0.011022513,0.015785662,0.0004813583,0.0030513487,0.002543984,0.00040164337,0.0010813087,0.0007790775,0.9648531],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99328864,0.000763302,0.0016700994,0.00201295,0.0006408601,0.0016241708],"domain_scores_gemma":[0.99318033,0.00025193946,0.002936482,0.0025258982,0.00030454027,0.0008008089],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"category_scores_codex":[0.0013148887,0.0015534853,0.0016773195,0.00074107485,0.0010398361,0.0003165199,0.0010241492,0.0040020444,0.00817905],"category_scores_gemma":[0.00033842368,0.0013959904,0.00051997823,0.0003356983,0.0007272882,0.00055500434,0.00034129873,0.0034734528,0.0022603036],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011490128,0.0004265742,0.0007897846,0.00018008052,0.00069285603,0.001278516,0.0011395209,0.000008038463,0.0022587974,0.000035763223,0.9235374,0.068503685],"study_design_scores_gemma":[0.0033733689,0.00020367528,0.00039663544,0.00023857458,0.00047235028,0.00062844995,0.00019739129,0.000035597437,0.0022025572,0.0001954403,0.99041057,0.0016453714],"about_ca_topic_score_codex":0.050887737,"about_ca_topic_score_gemma":0.055624757,"teacher_disagreement_score":0.066873215,"about_ca_system_score_codex":0.00028055534,"about_ca_system_score_gemma":0.0008443057,"threshold_uncertainty_score":0.99972135},"labels":[],"label_agreement":null},{"id":"W7034353609","doi":"","title":"Spindrift Live at The Connecticut Yankee on 2007-03-23","year":2007,"lang":"en","type":"other","venue":"Bulletin of Miscellaneous Information (Royal Gardens Kew)","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Yankee; Guitar; Bass (fish); Mile; Nova scotia","score_opus":0.03427007211963042,"score_gpt":0.30018224099693447,"score_spread":0.26591216887730407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7034353609","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00066914695,0.0004014337,5.2035335e-7,0.00052684057,0.0025701323,0.0013218306,0.00028241597,0.00025032842,0.99397737],"genre_scores_gemma":[0.0027610266,0.0005996029,0.000062194165,0.0039937696,0.00081941235,0.00005593577,0.00019388458,0.00014770568,0.99136645],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974686,0.0004345171,0.0007427252,0.00032522963,0.00045416682,0.0005747576],"domain_scores_gemma":[0.9976507,0.0006794627,0.0008426367,0.000458107,0.00015542073,0.0002136762],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0010429315,0.0005203536,0.00049700524,0.0001535037,0.00037528,0.000037531467,0.00045769266,0.0015537018,0.7584966],"category_scores_gemma":[0.0002431166,0.00043620536,0.00026491674,0.00001754073,0.00036399724,3.8324774e-7,0.0001410494,0.0015914192,0.22381923],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005364493,0.00012566704,0.0000075551734,0.00028682174,0.0002253882,0.000042149433,0.0003433503,0.0004494759,0.000003869371,0.00012687345,0.99383235,0.004020056],"study_design_scores_gemma":[0.0009912023,0.00030977363,0.000013457733,0.00015832456,0.00015938678,0.000135866,0.00013628867,0.00003978114,0.0005286715,0.000017614117,0.997047,0.0004626153],"about_ca_topic_score_codex":0.002151955,"about_ca_topic_score_gemma":0.001924327,"teacher_disagreement_score":0.5346773,"about_ca_system_score_codex":0.00017823183,"about_ca_system_score_gemma":0.000052944055,"threshold_uncertainty_score":0.99980897},"labels":[],"label_agreement":null},{"id":"W7034527351","doi":"","title":"Trevali Awarded New Brunswick Developer of the Year","year":2011,"lang":"en","type":"other","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Work (physics); Government (linguistics)","score_opus":0.18038477799855218,"score_gpt":0.403060788806256,"score_spread":0.22267601080770383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7034527351","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008303038,0.00039093883,0.0001454034,0.00030414085,0.0034502544,0.0008613727,0.000026319849,0.00018471005,0.99380654],"genre_scores_gemma":[0.0063613127,0.0004407942,0.0004293421,0.0011491036,0.0006602875,0.000013215049,0.000008190317,0.00021940737,0.99071836],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985021,0.000413197,0.00032119767,0.0002959915,0.00016397594,0.0003035799],"domain_scores_gemma":[0.9990676,0.000056496785,0.0003046098,0.00038416963,0.000040352712,0.00014676644],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00036814724,0.00029211256,0.00036493113,0.00014110738,0.000092868766,0.0000052154664,0.0005013909,0.0012710062,0.07297537],"category_scores_gemma":[0.000052051924,0.000204249,0.00018571044,0.00022994172,0.0001671647,0.000028453458,0.00012480996,0.00115219,0.0020030371],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000068650465,0.00009931139,0.0026291378,0.00012258814,0.00029479276,0.0000021054027,0.0004288926,0.000001774229,0.0011825891,0.006743777,0.9759909,0.012435502],"study_design_scores_gemma":[0.0006940285,0.000027430884,0.0011253795,0.000067312576,0.00014469572,0.000005593498,0.000024113746,0.0000047870103,0.031910095,0.00041259787,0.965328,0.00025597686],"about_ca_topic_score_codex":0.0049657375,"about_ca_topic_score_gemma":0.004829024,"teacher_disagreement_score":0.07097233,"about_ca_system_score_codex":0.00004267962,"about_ca_system_score_gemma":0.00085699605,"threshold_uncertainty_score":0.998774},"labels":[],"label_agreement":null},{"id":"W7038923251","doi":"","title":"La combinaison de l'UDCA ou du NCX-1000 avec des antioxydants liposolubles procure une meilleure protection aux hépatocytes de souris contre la toxicité de l'amiodarone","year":2016,"lang":"fr","type":"dissertation","venue":"Papyrus : Institutional Repository (Université de Montréal)","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Université de Montréal","keywords":"Quality (philosophy); Context (archaeology); Power (physics); Scope (computer science)","score_opus":0.023091862820703864,"score_gpt":0.269478321249257,"score_spread":0.24638645842855317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7038923251","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9619937,0.009156419,0.002675176,0.002182886,0.0017604774,0.0020029675,0.000287558,0.00040928277,0.019531557],"genre_scores_gemma":[0.96541256,0.0047916663,0.00041516803,0.00028326863,0.0007129467,0.00038837123,0.00022025134,0.000116358606,0.027659383],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9929652,0.00309086,0.0008117604,0.0010729627,0.0006196301,0.0014395864],"domain_scores_gemma":[0.99637026,0.0007188684,0.0009491374,0.0004112734,0.0006673278,0.0008831609],"candidate_categories":["metaepi_narrow","sts","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0016495903,0.0010538929,0.000900247,0.0005546243,0.012642146,0.00016608619,0.0007006189,0.0035283312,0.00018224989],"category_scores_gemma":[0.00028682174,0.0011707217,0.0005965874,0.0006733985,0.0012951575,0.0007915013,0.00019728477,0.0028468398,0.00010928082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":true,"study_design_scores_codex":[0.008573823,0.0024708668,0.08295287,0.0021125313,0.0023008317,0.00545036,0.093673855,0.003876038,0.72233707,0.021052415,0.0009366616,0.054262683],"study_design_scores_gemma":[0.009181531,0.0008950089,0.09333186,0.002310194,0.0022916915,0.0096807955,0.019888707,0.011595225,0.67477196,0.0054146037,0.16837658,0.0022618114],"about_ca_topic_score_codex":0.029135836,"about_ca_topic_score_gemma":0.015145245,"teacher_disagreement_score":0.16743992,"about_ca_system_score_codex":0.009502827,"about_ca_system_score_gemma":0.006001392,"threshold_uncertainty_score":0.99963367},"labels":[],"label_agreement":null},{"id":"W7084391164","doi":"10.5281/zenodo.17253871","title":"Two-way travel (TWT) time retrievals of subsurface reflectors in Phlegra Montes, Mars using SHallow RADar (SHARAD)","year":2025,"lang":"en","type":"dataset","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Ground-penetrating radar; Radar; Mars Exploration Program; Dielectric permittivity; Radar imaging; Surface (topology); Glaciology","score_opus":0.14090652162723455,"score_gpt":0.39862656721409323,"score_spread":0.2577200455868587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7084391164","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.017958267,0.00049833406,0.00016880281,0.00026285887,0.00084114016,0.0020527097,0.96284807,0.00033589551,0.015033939],"genre_scores_gemma":[0.019918814,0.0009633517,0.00020448721,0.00038032234,0.00029726417,3.8086648e-7,0.9756153,0.00087257015,0.0017474946],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9947255,0.0024612136,0.0008327965,0.00079005887,0.0004939755,0.0006964118],"domain_scores_gemma":[0.9979101,0.00018064056,0.0004921147,0.00068669853,0.00048411565,0.0002463762],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.002618353,0.0004460143,0.00067713496,0.0009030141,0.0012851058,0.00018252632,0.0015645896,0.000782322,0.012953733],"category_scores_gemma":[0.0010374322,0.000518381,0.00016849466,0.0015537237,0.0002888938,0.0002361009,0.00096489023,0.0024116142,0.001087486],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069058203,0.0005325781,0.000007559526,0.0005912252,0.00024475052,0.00006905033,0.00029260275,0.00041539347,0.05801297,0.00010581843,0.9292191,0.00981832],"study_design_scores_gemma":[0.0015269005,0.00021534043,0.000074755044,0.00020794869,0.0001454526,0.00005610533,0.000070831324,0.0015506848,0.010079925,0.00007171042,0.98556536,0.00043496708],"about_ca_topic_score_codex":0.0005219442,"about_ca_topic_score_gemma":0.000019109864,"teacher_disagreement_score":0.05634623,"about_ca_system_score_codex":0.00060568994,"about_ca_system_score_gemma":0.000048519167,"threshold_uncertainty_score":0.99988985},"labels":[],"label_agreement":null},{"id":"W7118012597","doi":"10.1007/978-3-032-10050-4_25","title":"Liver Function Assessment","year":2025,"lang":"en","type":"book-chapter","venue":"","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Health; Alberta Health Services","funders":"","keywords":"Drug; Liver function tests; Liver function; Liver toxicity; Multitude; Human liver; Liver dysfunction; Liver damage","score_opus":0.15106976894137122,"score_gpt":0.4287318690435475,"score_spread":0.2776621001021763,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7118012597","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00005017584,0.00041453994,0.0027236117,0.00044170322,0.004797898,0.00086165295,0.000074389536,0.00031982112,0.9903162],"genre_scores_gemma":[0.01111526,0.000828966,0.00023004468,0.004397658,0.00072479754,0.000076992976,0.0001333292,0.000040896088,0.98245203],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984039,0.00014318412,0.00040527782,0.0005127439,0.00021430035,0.00032059485],"domain_scores_gemma":[0.99897957,0.0002298596,0.00020154977,0.00029070725,0.00014224737,0.0001560685],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.00056478544,0.00042826746,0.0003979942,0.0002799173,0.0003671806,0.000031279505,0.00020559845,0.0018866839,0.028427735],"category_scores_gemma":[0.000014670111,0.00043116408,0.00025304712,0.000050432875,0.000104100676,0.00010272752,0.00012652414,0.0026523685,0.0017640652],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016941717,0.00010174849,0.00003989481,0.00021025026,0.00060272735,0.00004309617,0.000037760907,0.000031090483,0.0006670591,0.593597,0.092853844,0.3116461],"study_design_scores_gemma":[0.0005207943,0.00012950078,0.00007028046,0.00006233285,0.00045218036,0.000009803252,0.000005812675,0.00090308086,0.0014726041,0.019415203,0.97654486,0.0004135346],"about_ca_topic_score_codex":0.000035384495,"about_ca_topic_score_gemma":0.000075545,"teacher_disagreement_score":0.883691,"about_ca_system_score_codex":0.00031210604,"about_ca_system_score_gemma":0.00027424208,"threshold_uncertainty_score":0.99981403},"labels":[],"label_agreement":null},{"id":"W7128371256","doi":"10.1080/14622416.2026.2624364","title":"The role of NAT2 genetic variants in anti-tuberculosis drug-induced liver injury (AT-DILI): a meta-analysis","year":2025,"lang":"en","type":"article","venue":"Pharmacogenomics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Liver injury; Genetic variants; Genetic variation; Pharmacogenetics; Gene; Genotype","score_opus":0.09736738622647005,"score_gpt":0.39714595269565756,"score_spread":0.2997785664691875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7128371256","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9848891,0.0076581785,0.000044929693,0.00072602264,0.000876272,0.0011294186,0.00022029012,0.00006271141,0.0043931147],"genre_scores_gemma":[0.9946113,0.0029055034,0.00011351048,0.0012642599,0.00009215985,0.0002964575,0.000016433267,0.000032969736,0.0006673951],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9959617,0.0014614911,0.0010089411,0.0006293978,0.000249024,0.000689445],"domain_scores_gemma":[0.99796027,0.0007865823,0.00039271312,0.0005114591,0.0001712071,0.00017778565],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0020287253,0.0004257083,0.0010355382,0.0006716271,0.00063986285,0.000041311043,0.0007361014,0.0003821694,0.00086655346],"category_scores_gemma":[0.00008123534,0.00036453744,0.0010053726,0.0018465128,0.00019202805,0.00013759956,0.0003549351,0.0011066399,0.00010911817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010246136,0.0009666109,0.022092348,0.00012421657,0.09910612,0.000042705666,0.0015410311,0.007957472,0.8226858,0.0012079239,0.00064245565,0.042608753],"study_design_scores_gemma":[0.0012713796,0.000038537764,0.0063403985,0.000004366956,0.06919897,0.000008184807,0.0001271718,0.035170622,0.83311707,0.0014035895,0.052841283,0.00047843947],"about_ca_topic_score_codex":0.0007038533,"about_ca_topic_score_gemma":0.00072355726,"teacher_disagreement_score":0.052198827,"about_ca_system_score_codex":0.0003265819,"about_ca_system_score_gemma":0.00019581585,"threshold_uncertainty_score":0.9998807},"labels":[],"label_agreement":null},{"id":"W83034125","doi":"10.1016/b978-0-12-398339-8.00003-3","title":"Animal Models of Idiosyncratic Drug Reactions","year":2012,"lang":"en","type":"review","venue":"Advances in pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":58,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Therapure Biopharma (Canada); University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Mechanism (biology); Immune system; Drug; Rash; Medicine; Pharmacology; Immunology; Internal medicine","score_opus":0.24060955753826507,"score_gpt":0.5122178013078554,"score_spread":0.27160824376959036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W83034125","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00025161906,0.97861606,0.00010138867,0.00006154946,0.006675592,0.0019598962,0.00015598894,0.00011582466,0.012062096],"genre_scores_gemma":[0.011759867,0.9852206,0.00022419902,0.0002248842,0.00091337494,0.0010096348,0.000070830174,0.000091085494,0.00048550838],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99386394,0.0025948915,0.0016807764,0.00066869095,0.000216028,0.0009756665],"domain_scores_gemma":[0.996631,0.0015060229,0.001161139,0.00031785076,0.00010196103,0.00028200183],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0016775919,0.0007166157,0.0022511885,0.000749616,0.00021502117,0.000008283096,0.00067273097,0.0012234509,0.0014559081],"category_scores_gemma":[0.00005140533,0.00070249406,0.0004999671,0.0009482149,0.0004224249,0.0009382437,0.00019908267,0.0034544412,0.00025373755],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017469963,0.0008416826,0.000025303869,0.016254673,0.0003701244,0.00004376879,0.00034967586,0.0008551739,0.00055069773,0.0030290545,0.00044262555,0.9770625],"study_design_scores_gemma":[0.00080940704,0.000092626186,0.0000010481343,0.0008741381,0.0017681214,0.0001238532,0.00003316092,0.00065268384,0.0013016602,0.0016662519,0.99209553,0.0005815242],"about_ca_topic_score_codex":0.00003506977,"about_ca_topic_score_gemma":0.00005290996,"teacher_disagreement_score":0.9916529,"about_ca_system_score_codex":0.00040096085,"about_ca_system_score_gemma":0.00034573994,"threshold_uncertainty_score":0.9995426},"labels":[],"label_agreement":null},{"id":"W973722855","doi":"10.1007/s40262-015-0301-3","title":"Population Pharmacokinetics of Intravenous Paracetamol (Acetaminophen) in Preterm and Term Neonates: Model Development and External Evaluation","year":2015,"lang":"en","type":"article","venue":"Clinical Pharmacokinetics","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":58,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of Child Health and Human Development; National Institutes of Health; National Center for Advancing Translational Sciences; Children's National Hospital; Fonds Wetenschappelijk Onderzoek; American Foundation for Pharmaceutical Education; Vlaamse regering; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Howard Hughes Medical Institute","keywords":"NONMEM; Gestational age; Medicine; Acetaminophen; Population; Volume of distribution; Confidence interval; Coefficient of variation; Birth weight; Standard error; Anesthesia; Pharmacokinetics; Statistics; Internal medicine; Pregnancy; Mathematics","score_opus":0.3384928192421123,"score_gpt":0.5012615931518831,"score_spread":0.16276877390977085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W973722855","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99417835,0.0015901863,0.0011010318,0.0001657086,0.0010708832,0.001294136,0.000023678287,0.00005094373,0.0005250565],"genre_scores_gemma":[0.9947467,0.0010180554,0.0031317302,0.00059170974,0.00025099135,0.00009946284,0.000037817274,0.000035881993,0.00008765345],"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99615324,0.000996636,0.0014039604,0.0005624939,0.00044811456,0.000435537],"domain_scores_gemma":[0.9981532,0.00043157136,0.00047070577,0.00019008438,0.00026840865,0.00048601272],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004126067,0.00034302677,0.0005683379,0.00021409748,0.000110420944,0.0000299085,0.00021529326,0.00049210724,0.00006490947],"category_scores_gemma":[0.000363351,0.00035620105,0.000068202695,0.0002235723,0.00029716405,0.00021835964,0.00017952108,0.0011577077,0.0000099745685],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013390767,0.0010235518,0.13378705,0.00028495886,0.00017115219,0.000025250532,0.0042535057,0.021776324,0.021374632,0.00014284845,0.00010911228,0.8157125],"study_design_scores_gemma":[0.012668444,0.00040705138,0.105749145,0.00013214075,0.00059471634,0.000048528513,0.00009032792,0.8250756,0.04721236,0.0035101653,0.0038543367,0.0006571915],"about_ca_topic_score_codex":0.000023570035,"about_ca_topic_score_gemma":0.000022735592,"teacher_disagreement_score":0.8150553,"about_ca_system_score_codex":0.00014434877,"about_ca_system_score_gemma":0.00021381816,"threshold_uncertainty_score":0.999889},"labels":[],"label_agreement":null}]}