{"meta":{"query_hash":"8aaea33d6f0c","filters":{"topic":"Protein purification and stability"},"cohort_total":371,"direct_labels_cover":1,"predictions_cover":371,"exported":371,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/8aaea33d6f0c","api":"https://metacan.xera.ac/api/v1/cohort?topic=Protein+purification+and+stability"},"results":[{"id":"W1086543529","doi":"10.1016/j.chroma.2015.08.004","title":"Determination of adsorption isotherm parameters for minor whey proteins by gradient elution preparative liquid chromatography","year":2015,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland; Western University","funders":"","keywords":"Chemistry; Chromatography; Elution; Adsorption; Simulated moving bed; Fractionation; Whey protein; Expanded bed adsorption; Organic chemistry","score_opus":0.018164706278870887,"score_gpt":0.2710957167297625,"score_spread":0.2529310104508916,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1086543529","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9290322,0.0020347156,0.06774693,0.00010693789,0.0001248921,0.0007781302,0.000061605926,0.000008413042,0.00010614933],"genre_scores_gemma":[0.98792136,0.00011324997,0.011693054,0.000037877708,0.000058342514,0.0000983212,0.000049032475,0.000015314452,0.00001344187],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985792,0.00014785003,0.0006154574,0.00021257489,0.0002716787,0.00017322564],"domain_scores_gemma":[0.9980646,0.000015314936,0.0008854845,0.00025095107,0.00063677685,0.00014691637],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00066180836,0.00016122076,0.00026316947,0.00020937182,0.000040856514,0.00001880019,0.00019387915,0.00015346313,0.0000037311938],"category_scores_gemma":[0.00016167841,0.00014256353,0.00039541256,0.0002295493,0.00016075782,0.00002896122,0.000017724915,0.00007362478,4.1956628e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016406216,0.000543848,0.0015565015,0.0001054988,0.00015075313,5.134071e-7,0.0004897766,0.000015318614,0.9914986,0.00011646375,0.0018027422,0.0020793863],"study_design_scores_gemma":[0.002136114,0.00581321,0.0017101637,0.000079477286,0.00007986726,0.00004931847,0.00028247116,0.00018494242,0.97758156,0.0009377587,0.010908842,0.00023630372],"about_ca_topic_score_codex":0.000008244413,"about_ca_topic_score_gemma":0.000009446301,"teacher_disagreement_score":0.05888914,"about_ca_system_score_codex":0.00002690004,"about_ca_system_score_gemma":0.00012047486,"threshold_uncertainty_score":0.5813572},"labels":[],"label_agreement":null},{"id":"W1128661185","doi":"10.1016/j.chroma.2015.08.056","title":"Negative chromatography purification of hepatitis B virus-like particles using poly(oligo(ethylene glycol) methacrylate) grafted cationic adsorbent","year":2015,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Ministério da Ciência, Tecnologia e Inovação; Canadian Bureau for International Education","keywords":"Chemistry; Ethylene glycol; Size-exclusion chromatography; Chromatography; Elution; Adsorption; Cationic polymerization; Methacrylate; Polymer chemistry; Polymer; Monomer; Nuclear chemistry; Organic chemistry","score_opus":0.024025283314541974,"score_gpt":0.27480585614101777,"score_spread":0.2507805728264758,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1128661185","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98478067,0.0078275055,0.0065568886,0.00015336927,0.00020660475,0.000314935,0.00005440509,0.0000149088655,0.00009072811],"genre_scores_gemma":[0.98836625,0.0009569788,0.010420572,0.00008496708,0.000106829546,0.00001816846,0.000017384698,0.00002422053,0.0000046146342],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976899,0.00033405784,0.000964945,0.00027762083,0.00047487672,0.00025858343],"domain_scores_gemma":[0.99706024,0.000032691605,0.0011435169,0.0004881891,0.0009976872,0.00027767118],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008490147,0.00022264638,0.00038821166,0.00034644906,0.00008746137,0.000038423408,0.00033129012,0.0001815828,0.000021631431],"category_scores_gemma":[0.00022357247,0.00020618529,0.00042506316,0.0007815914,0.0002840951,0.00004269965,0.000049078695,0.00015246791,0.0000018827251],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041166026,0.0005870252,0.05550594,0.0000669654,0.00047961957,0.00000493197,0.00069172104,0.00012184468,0.9389201,0.00030499103,0.00031610279,0.0025891266],"study_design_scores_gemma":[0.0016037493,0.0007212947,0.08341853,0.00007910245,0.0001481052,0.000102537815,0.0003198833,0.00030159473,0.90768284,0.0021766718,0.0031440472,0.0003016448],"about_ca_topic_score_codex":0.0003009699,"about_ca_topic_score_gemma":0.00013170038,"teacher_disagreement_score":0.031237243,"about_ca_system_score_codex":0.00004213166,"about_ca_system_score_gemma":0.0003598806,"threshold_uncertainty_score":0.8407992},"labels":[],"label_agreement":null},{"id":"W1189282217","doi":"10.1016/j.ces.2015.08.031","title":"Oxidative protein refolding on size exclusion chromatography: From batch single-column to multi-column counter-current continuous processing","year":2015,"lang":"en","type":"article","venue":"Chemical Engineering Science","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland; Western University","funders":"","keywords":"Simulated moving bed; Chemistry; Size-exclusion chromatography; Chromatography; Chaotropic agent; Downstream processing; Column (typography); Work (physics); Reagent; Adsorption; Thermodynamics; Organic chemistry; Computer science","score_opus":0.021236237478899044,"score_gpt":0.2643594216593108,"score_spread":0.24312318418041176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1189282217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9804796,0.00034842218,0.018273955,0.00010236384,0.00015056542,0.0004850724,0.000017135835,0.00007353333,0.000069351656],"genre_scores_gemma":[0.9831389,0.0000018229913,0.016533716,0.00006545738,0.00009881449,0.00010446515,0.000016183441,0.000017858478,0.000022791544],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982896,0.000016760869,0.00024009398,0.0006956814,0.000392862,0.00036499603],"domain_scores_gemma":[0.9989073,0.00001891505,0.000072876384,0.0004029358,0.0002523105,0.00034561698],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041228498,0.00019359068,0.00017227502,0.000055364228,0.000094168565,0.000103971885,0.00047763888,0.00009399566,0.000004590286],"category_scores_gemma":[0.0017288867,0.00019060606,0.000050952032,0.0004446913,0.00018086485,0.000021129086,0.00021092301,0.00015502995,0.000008717487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035744724,0.00013404613,0.000100893194,0.000018588275,0.0000030850003,7.2160503e-7,0.0002137865,0.00010392203,0.99526334,0.000008334018,0.000026226731,0.0040913415],"study_design_scores_gemma":[0.00040592585,0.0001202541,0.00055745087,0.00014223601,0.0000034037564,0.0000014565352,0.000049766255,0.0032848597,0.99244976,0.000019750056,0.002702658,0.00026247755],"about_ca_topic_score_codex":0.000016629514,"about_ca_topic_score_gemma":0.0000013829722,"teacher_disagreement_score":0.0038288638,"about_ca_system_score_codex":0.00015341795,"about_ca_system_score_gemma":0.00015559052,"threshold_uncertainty_score":0.77726895},"labels":[],"label_agreement":null},{"id":"W1481675000","doi":"10.1023/a:1010938111292","title":"Purification and characterization of β‐methylaspartase from Fusobacterium varium","year":2001,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Chemistry; Deamination; Ammonium sulfate precipitation; Chromatography; Enzyme; Yield (engineering); Size-exclusion chromatography; Ion chromatography; Ammonium sulfate; Specific activity; Biochemistry","score_opus":0.005046854487907085,"score_gpt":0.2009265526467267,"score_spread":0.19587969815881962,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1481675000","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9853115,0.001568826,0.012358043,0.00021454965,0.000029727233,0.00014257214,0.00008454092,0.00001122207,0.00027902235],"genre_scores_gemma":[0.997281,0.00016496351,0.0004285106,0.000105828476,0.000057442045,0.000021063972,0.0017982001,0.000014917762,0.0001280792],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904203,0.000055900826,0.00022787676,0.00041490173,0.00010380015,0.00015547997],"domain_scores_gemma":[0.9992712,0.000005086682,0.000114802286,0.00040945018,0.00008101889,0.000118452896],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013709084,0.00014925972,0.00013714438,0.00002129012,0.000046578785,0.000024901772,0.00009817467,0.00018538028,0.0000295251],"category_scores_gemma":[0.00004702503,0.00016043242,0.000046597503,0.00007306289,0.00012649431,0.0000052626524,0.00006887141,0.00006490941,0.0000013472306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006096068,0.00006314147,0.0026662597,0.000033979286,0.000026207057,0.0000030411777,0.000015859614,1.4673202e-7,0.99501973,0.000078270255,0.000005182031,0.0020272294],"study_design_scores_gemma":[0.0003079555,0.000041457282,0.003461459,0.000008114944,0.000024552675,0.000007845773,0.000028383796,0.00002790916,0.9922381,0.000119915654,0.0035698977,0.00016443143],"about_ca_topic_score_codex":0.000017542872,"about_ca_topic_score_gemma":7.4536854e-7,"teacher_disagreement_score":0.011969498,"about_ca_system_score_codex":0.00000662672,"about_ca_system_score_gemma":0.00003098174,"threshold_uncertainty_score":0.65422446},"labels":[],"label_agreement":null},{"id":"W1487843056","doi":"10.1002/9781118870914.ch6","title":"Protein Subunit Vaccine Purification","year":2014,"lang":"en","type":"other","venue":"","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Biopharmaceutical; Protein subunit; Process development; Automation; Process (computing); Product (mathematics); Biotechnology; Engineering; Computer science; Biology; Process engineering; Biochemistry; Gene","score_opus":0.007867023304131752,"score_gpt":0.23604423245603381,"score_spread":0.22817720915190207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1487843056","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00034194233,0.0016823612,0.015935786,0.0004661575,0.000097982345,0.0010680521,0.00003200188,0.00013761412,0.9802381],"genre_scores_gemma":[0.022736318,0.000098911005,0.0017196618,0.00017290375,0.00041627078,0.00018532548,0.00066571473,0.00020289609,0.973802],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99910057,0.000076006116,0.00016934359,0.00041165846,0.00010024232,0.00014220229],"domain_scores_gemma":[0.9989049,0.0000017043773,0.00013457924,0.00084613566,0.00004667467,0.000066027],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00017054837,0.00017885111,0.00014651762,0.000057285106,0.00002505234,0.000015607293,0.00022896919,0.00038470794,0.0028314488],"category_scores_gemma":[0.00007620136,0.00015920514,0.000064676584,0.00005318848,0.000026645137,5.2599785e-7,0.000042353655,0.000082917824,0.00043638598],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037219655,0.00011698449,0.00014235673,0.00012827438,0.000063946594,3.0296133e-7,0.000003946485,2.7123625e-7,0.14895985,0.003615908,0.83550733,0.011423644],"study_design_scores_gemma":[0.00019871436,0.000051307812,0.00016206874,0.000013678787,0.0000064740766,0.0000010143343,0.0000026234572,0.0000052559685,0.032298885,0.000065452274,0.96700007,0.00019448552],"about_ca_topic_score_codex":0.000043782828,"about_ca_topic_score_gemma":0.00013688224,"teacher_disagreement_score":0.13149273,"about_ca_system_score_codex":0.0000072592893,"about_ca_system_score_gemma":0.00004585353,"threshold_uncertainty_score":0.9980801},"labels":[],"label_agreement":null},{"id":"W1521151466","doi":"10.1016/s1872-2075(09)60011-x","title":"Stability Improvement of a Therapeutic Protein by Reducing Agent Pretreatment","year":2008,"lang":"en","type":"article","venue":"Chinese journal of biotechnology/Shengwu gongcheng xuebao","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Recombinant DNA; Protein stability; Chemistry; Reducing agent; Extracellular; Biochemistry","score_opus":0.011678797976266512,"score_gpt":0.23879378560984707,"score_spread":0.22711498763358057,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1521151466","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9874067,0.0073653497,0.0033345746,0.00090637035,0.0001416841,0.00067472056,0.000034107434,0.00002603446,0.00011050679],"genre_scores_gemma":[0.9973074,0.0007080205,0.0016547398,0.000049460526,0.000074855714,0.000040385366,0.000018570647,0.000025949756,0.00012061412],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99786484,0.00012433075,0.00095720385,0.0004174177,0.00031749398,0.00031873878],"domain_scores_gemma":[0.99791664,0.000021446109,0.00076115294,0.0008617899,0.0003139271,0.00012505775],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00078537664,0.0003193833,0.0005086211,0.00013362014,0.00012981198,0.000010528661,0.00052521715,0.0004510591,0.000037865324],"category_scores_gemma":[0.00046317905,0.00023190498,0.0003059086,0.0002860214,0.0004589603,0.000016626289,0.00013894873,0.00042438798,0.0000022914812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026282467,0.0007301828,0.003591346,0.000064118896,0.00019169548,0.00000599643,0.000188811,0.000010246951,0.9845561,0.000044415086,0.00011188206,0.010242394],"study_design_scores_gemma":[0.0011661897,0.0015388699,0.0032523694,0.000034815,0.000034123772,0.00009005488,0.00013252597,0.000037252143,0.9898416,0.00035142797,0.003306499,0.00021428222],"about_ca_topic_score_codex":0.0000348958,"about_ca_topic_score_gemma":0.000006379682,"teacher_disagreement_score":0.010028112,"about_ca_system_score_codex":0.00012926146,"about_ca_system_score_gemma":0.0002453472,"threshold_uncertainty_score":0.94568104},"labels":[],"label_agreement":null},{"id":"W1572971914","doi":"10.1002/btpr.2148","title":"Selecting polymers for two‐phase partitioning bioreactors ( <scp>TPPB</scp> s): Consideration of thermodynamic affinity, crystallinity, and glass transition temperature","year":2015,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Crystallinity; Polymer; Amorphous solid; Glass transition; Dissolution; Chemical engineering; Partition coefficient; Materials science; Phase (matter); Thermodynamics; Chemistry; Organic chemistry; Composite material","score_opus":0.019215065974046767,"score_gpt":0.2917327341914786,"score_spread":0.27251766821743184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1572971914","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926962,0.0022656224,0.0031245744,0.0009815989,0.00007168439,0.0006424034,0.0000957853,0.00007554959,0.00004657037],"genre_scores_gemma":[0.9972627,0.000052200354,0.0021623434,0.000054493306,0.00004961881,0.000112893424,0.00027909322,0.00001730221,0.000009365358],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896544,0.00008985214,0.00026760978,0.0003636191,0.000095558746,0.00021794562],"domain_scores_gemma":[0.999182,0.000037337795,0.00017686184,0.00032285703,0.00020694286,0.000074000716],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040859255,0.00015491275,0.00017930097,0.00008688197,0.00012920363,0.000032009255,0.0001383724,0.0004902971,0.0000012306919],"category_scores_gemma":[0.0005482811,0.000152387,0.00005496178,0.00014075612,0.00042077206,0.000012658088,0.000060798957,0.00014233151,3.150199e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010292317,0.00024524474,0.0013078633,0.000057150515,0.000063362626,8.809475e-7,0.00022967314,0.00001574044,0.98803514,0.0023370802,0.00006728514,0.0075376616],"study_design_scores_gemma":[0.0022810495,0.0008120842,0.000348595,0.00002199937,0.00003468537,0.000027769081,0.0006351481,0.0009899329,0.9925293,0.0009139234,0.0013002102,0.000105341256],"about_ca_topic_score_codex":0.0000110346755,"about_ca_topic_score_gemma":0.0000461485,"teacher_disagreement_score":0.00743232,"about_ca_system_score_codex":0.000018539185,"about_ca_system_score_gemma":0.00012075387,"threshold_uncertainty_score":0.62141615},"labels":[],"label_agreement":null},{"id":"W170754621","doi":"10.1007/978-3-642-01888-6_8","title":"A Computational Intelligent Based Approach for the Development of a Minimal Defined Medium: Application to Human Interleukin-3 Production by Streptomyces lividans 66","year":2009,"lang":"en","type":"book-chapter","venue":"Studies in computational intelligence","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Amino acid; Recombinant DNA; Biochemistry; Biology; Computational biology; Chemistry; Gene","score_opus":0.06234597855626741,"score_gpt":0.3455041827782658,"score_spread":0.2831582042219984,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W170754621","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008946086,0.0023676334,0.9924594,0.0006132607,0.00012327329,0.0022017001,0.00010655043,0.000017758703,0.001215818],"genre_scores_gemma":[0.85574985,0.00008250426,0.1374836,0.00023897282,0.00016679538,0.0010432559,0.0019917928,0.00003816798,0.0032050614],"study_design_codex":"simulation_or_modeling","study_design_gemma":"not_applicable","domain_scores_codex":[0.99767077,0.000042700183,0.00096147356,0.0007489956,0.00038982512,0.00018626364],"domain_scores_gemma":[0.99818134,0.00025019408,0.00038844065,0.00031288454,0.00081461645,0.000052542182],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00067762355,0.00032278814,0.0003379564,0.00013583097,0.00020264514,0.000016804483,0.0004219588,0.00015586818,0.000008818074],"category_scores_gemma":[0.00024748623,0.0002815646,0.00012914544,0.00009836899,0.00034571215,0.0000055961177,0.00012625448,0.00015712364,0.0000039287575],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007232088,0.00086331624,0.00017147574,0.0007914061,0.00079413125,4.022697e-7,0.0040104096,0.7775146,0.002476229,0.028596714,0.0035498722,0.18050823],"study_design_scores_gemma":[0.002471163,0.0047649126,0.0032181,0.002031646,0.0005598093,0.000030822084,0.0076764384,0.18021153,0.20622176,0.24992217,0.33705896,0.0058326893],"about_ca_topic_score_codex":0.0000033348208,"about_ca_topic_score_gemma":0.00005963837,"teacher_disagreement_score":0.8549758,"about_ca_system_score_codex":0.00015824431,"about_ca_system_score_gemma":0.00029399313,"threshold_uncertainty_score":0.99996364},"labels":[],"label_agreement":null},{"id":"W1776230857","doi":"10.1002/btpr.2113","title":"Advective hydrogel membrane chromatography for monoclonal antibody purification in bioprocessing","year":2015,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Natrix Separations (Canada)","funders":"","keywords":"Chemistry; Chromatography; Membrane; Downstream processing; Monoclonal antibody; Bioprocess; Ion chromatography; Yield (engineering); Column chromatography; Affinity chromatography; Elution; Biochemistry; Chemical engineering; Materials science; Antibody; Biology","score_opus":0.019540839471737802,"score_gpt":0.3042979814777156,"score_spread":0.2847571420059778,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1776230857","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9846568,0.005797687,0.0067589167,0.0015816098,0.000090899746,0.00086889626,0.00002731391,0.00010336192,0.00011449071],"genre_scores_gemma":[0.9907262,0.000086514076,0.008413836,0.00004638425,0.000049091104,0.00041163474,0.00022475043,0.000018456034,0.00002316377],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99879587,0.00003432923,0.00025712478,0.000529603,0.00009997628,0.0002831108],"domain_scores_gemma":[0.99922013,0.000006505596,0.00012824858,0.00042680764,0.0001478198,0.000070462986],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003988066,0.00015739069,0.00016860658,0.0001837752,0.00006832022,0.000018191955,0.00029240927,0.00053140684,0.000001416526],"category_scores_gemma":[0.00016875779,0.00015634886,0.00006691473,0.0003514139,0.00039408077,0.000008765282,0.0000674342,0.00010963929,0.0000039476486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036889745,0.0004576239,0.029960366,0.000076182645,0.000052362797,0.0000027138615,0.00008831529,0.0000074323584,0.9286411,0.0040856493,0.00006490004,0.0361945],"study_design_scores_gemma":[0.0012335595,0.00030548463,0.004802483,0.000017945173,0.000009676817,0.000018926183,0.00016187053,0.00043106888,0.97207826,0.0017873618,0.018906806,0.00024656425],"about_ca_topic_score_codex":0.000007848219,"about_ca_topic_score_gemma":0.000014982799,"teacher_disagreement_score":0.043437198,"about_ca_system_score_codex":0.000027759994,"about_ca_system_score_gemma":0.00012248388,"threshold_uncertainty_score":0.6375721},"labels":[],"label_agreement":null},{"id":"W1810954636","doi":"10.1016/s0076-6879(03)01026-7","title":"Evaluating Carbohydrate–Protein Binding Interactions Using Frontal Affinity Chromatography Coupled to Mass Spectrometry","year":2003,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Chromatography; Mass spectrometry; Electrospray ionization; Elution; Electrospray; Biotinylation; Affinity chromatography; Lectin; Dissociation constant; Sample preparation in mass spectrometry; Enzyme; Biochemistry","score_opus":0.08138085840285109,"score_gpt":0.4528883267801049,"score_spread":0.3715074683772538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1810954636","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.69658095,0.0005628181,0.29921424,0.00012448842,0.0011434335,0.0010158947,0.00001977677,0.000052191433,0.0012862134],"genre_scores_gemma":[0.39734074,0.00001678067,0.6017442,0.0002979139,0.00008682303,0.00033102013,0.000026683652,0.00006168436,0.0000941456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.97875357,0.016250392,0.0015189896,0.0018881127,0.00027991133,0.0013090437],"domain_scores_gemma":[0.99627364,0.0013109107,0.00047977892,0.0014580572,0.00018264586,0.00029494893],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.013748992,0.0007119408,0.0011947703,0.0015931494,0.00027764455,0.00004657215,0.0007450046,0.0010089941,0.0004348914],"category_scores_gemma":[0.010413105,0.00078570435,0.00033000758,0.0019041206,0.0004829406,0.000026503893,0.0002649378,0.0013757895,0.000032182856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003398816,0.00047564815,0.006327352,0.000032922555,0.00009728379,0.00003969155,0.00025169653,0.0010456286,0.9856539,0.0019268634,0.00001564033,0.0037935108],"study_design_scores_gemma":[0.002979403,0.0016279663,0.037839644,0.00010178166,0.00007608997,0.00030163268,0.00078085606,0.0019844812,0.93687505,0.013538524,0.0024259211,0.0014686616],"about_ca_topic_score_codex":0.00036170834,"about_ca_topic_score_gemma":0.00077941024,"teacher_disagreement_score":0.30252996,"about_ca_system_score_codex":0.0004402792,"about_ca_system_score_gemma":0.000312525,"threshold_uncertainty_score":0.9994594},"labels":[],"label_agreement":null},{"id":"W1847586862","doi":"10.1007/978-0-387-73657-0_23","title":"Molecular Modeling Approach to Achieving Erythropoietin Mimetic Peptides","year":2009,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Erythropoietin; Chemistry; Computational biology; Computer science; Medicine; Biology; Internal medicine","score_opus":0.024891575209181293,"score_gpt":0.34672893470012284,"score_spread":0.32183735949094155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1847586862","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9147024,0.0632496,0.015731758,0.00092376024,0.00007091499,0.00028838104,0.0000014728461,0.000012486872,0.005019183],"genre_scores_gemma":[0.9927316,0.00095037895,0.004675486,0.0014658561,0.00008505522,0.000036837293,0.000037940335,0.000006066363,0.000010835178],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990473,0.00006980629,0.00022015956,0.00041195485,0.00004861587,0.00020218726],"domain_scores_gemma":[0.9996578,0.0000079163165,0.00003262997,0.00019944664,0.000020267385,0.0000819477],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017492769,0.00013667985,0.00018043179,0.000058123125,0.00004495771,0.000003962305,0.000120067,0.000083787236,0.0000050573085],"category_scores_gemma":[0.0000950791,0.000109348315,0.000024589413,0.00009241217,0.00014490045,0.0000067577694,0.000051049527,0.0000723016,0.0000011354246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000078873185,0.00011894218,0.0006926796,0.00000713686,0.000003926414,7.164765e-7,0.00024054792,0.00022563832,0.98196805,0.0019183436,0.00001028345,0.014734887],"study_design_scores_gemma":[0.0036731993,0.0074195825,0.001536389,0.00014647354,0.000021857699,0.00008584692,0.008283713,0.0046286234,0.92020565,0.0050107306,0.0478606,0.0011273306],"about_ca_topic_score_codex":0.000012632537,"about_ca_topic_score_gemma":0.0000023416885,"teacher_disagreement_score":0.0780291,"about_ca_system_score_codex":0.000013060808,"about_ca_system_score_gemma":0.000009415709,"threshold_uncertainty_score":0.4459095},"labels":[],"label_agreement":null},{"id":"W1865824976","doi":"10.1080/19420862.2015.1069454","title":"Development of a quantitative mass spectrometry multi-attribute method for characterization, quality control testing and disposition of biologics","year":2015,"lang":"en","type":"article","venue":"mAbs","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":222,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Zymeworks (Canada)","funders":"","keywords":"Quality by Design; Orbitrap; Critical quality attributes; Computer science; Process analytical technology; Quality (philosophy); Process (computing); Identification (biology); Mass spectrometry; Pharmaceutical manufacturing; Biochemical engineering; Process engineering; Chromatography; Data mining; Chemistry; Work in process; Engineering; Pharmacology; Medicine","score_opus":0.10801251208153193,"score_gpt":0.37258677765215725,"score_spread":0.26457426557062536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1865824976","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.43824962,0.000082445564,0.56129074,0.000038413247,0.000015372236,0.0001919049,0.0001243592,0.0000028415125,0.000004290708],"genre_scores_gemma":[0.6085869,0.0000029175187,0.39119688,0.000015992151,0.0000059586687,0.000023665085,0.00015658155,0.000002422924,0.0000086871205],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993442,0.00010288244,0.00027424042,0.00015454466,0.000051767984,0.00007232481],"domain_scores_gemma":[0.99921983,0.0000721198,0.00020302416,0.00010511176,0.00036576545,0.000034152657],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008996643,0.00006018424,0.0001377604,0.00002229706,0.000028449604,0.0000038288294,0.000047788184,0.000060471553,8.89356e-7],"category_scores_gemma":[0.0018256273,0.00005320561,0.000022062597,0.00006779146,0.00004201216,0.0000029801806,0.000018082692,0.000020244104,1.5803096e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010947192,0.000053564385,0.01945291,0.00005564934,0.00002274863,2.0433463e-8,0.00011349786,0.0000015049002,0.9781014,0.00042169148,0.0000011461179,0.0016664313],"study_design_scores_gemma":[0.0013005541,0.0002830922,0.24269764,0.000011396514,0.000011530009,6.239528e-7,0.00021706893,0.0006803608,0.754049,0.00022273237,0.0004236183,0.00010238216],"about_ca_topic_score_codex":0.0000050820677,"about_ca_topic_score_gemma":0.0000037000273,"teacher_disagreement_score":0.22405237,"about_ca_system_score_codex":0.000011005582,"about_ca_system_score_gemma":0.00006310011,"threshold_uncertainty_score":0.21855782},"labels":[],"label_agreement":null},{"id":"W1923101441","doi":"10.1002/bit.25166","title":"A new mixed‐mode model for interpreting and predicting protein elution during isoelectric chromatofocusing","year":2013,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chromatofocusing; Isoelectric point; Elution; Chemistry; Isoelectric focusing; Chromatography; Ionic strength; Ion exchange; Equilibrium constant; Analytical Chemistry (journal); Aqueous solution; Thermodynamics; Ion; Physical chemistry; Biochemistry; Organic chemistry","score_opus":0.004337954674725478,"score_gpt":0.20470534127153095,"score_spread":0.20036738659680547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1923101441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.69974685,0.0011512304,0.2982148,0.0003647187,0.000020678533,0.0004117045,0.000004039242,0.000080029116,0.0000059554386],"genre_scores_gemma":[0.97659254,0.000074616335,0.023071663,0.000013732255,0.00004337247,0.000109219305,0.000010054988,0.00001564885,0.00006914291],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99921006,0.000009220236,0.00017093203,0.00033026535,0.000035891564,0.0002436553],"domain_scores_gemma":[0.99968743,0.0000059384197,0.000051044623,0.00016688522,0.000028108341,0.00006061157],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009571633,0.00013660289,0.00011280476,0.00008675491,0.00012509048,0.00002934103,0.000080289676,0.00031525322,0.0000013778007],"category_scores_gemma":[0.00011531152,0.00013641923,0.000028769236,0.000081236605,0.000052014817,0.00001291175,0.00009511613,0.00011514057,5.56685e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014335708,0.0000066813827,0.0004027371,0.00006931722,0.00001805346,1.1139771e-7,0.00002830377,0.000120581855,0.985294,0.0003124791,0.000008233324,0.0137251625],"study_design_scores_gemma":[0.0003194011,0.00007271504,0.0010068708,0.00003791898,0.000008014222,0.00002244987,0.000026671234,0.25878546,0.73913157,0.00029442346,0.00013219341,0.00016233358],"about_ca_topic_score_codex":0.00001987876,"about_ca_topic_score_gemma":0.000008405995,"teacher_disagreement_score":0.2768457,"about_ca_system_score_codex":0.000016433696,"about_ca_system_score_gemma":0.000024039984,"threshold_uncertainty_score":0.5563015},"labels":[],"label_agreement":null},{"id":"W1934086637","doi":"10.1002/jssc.201300511","title":"Purification and analysis of mono‐<scp>PEG</scp>ylated HSA by hydrophobic interaction membrane chromatography","year":2013,"lang":"en","type":"article","venue":"Journal of Separation Science","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; PEG ratio; Chromatography; Membrane; Elution; Lyotropic; Salt (chemistry); Hydrophobic effect; Gel permeation chromatography; Polyvinylidene fluoride; Hydrophilic interaction chromatography; High-performance liquid chromatography; Phase (matter); Organic chemistry; Biochemistry; Polymer","score_opus":0.009106738724265321,"score_gpt":0.28573018288971663,"score_spread":0.2766234441654513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1934086637","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99226576,0.00057166204,0.006612351,0.00011310377,0.00006118632,0.00012709982,0.0000052752434,0.00000293565,0.00024062624],"genre_scores_gemma":[0.9990181,0.00029376376,0.0005474978,0.000041504292,0.000016178776,0.000005874916,0.00001887366,0.0000027332617,0.00005547979],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894005,0.000058482052,0.0004393353,0.00018966553,0.00027411498,0.00009836164],"domain_scores_gemma":[0.9984924,0.000022642045,0.00056424283,0.00020249526,0.0006254257,0.00009280049],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006674373,0.000073168245,0.00015431692,0.00032493216,0.00008357587,0.00007021629,0.00018059541,0.00005930817,0.000017890576],"category_scores_gemma":[0.00020297906,0.00006226867,0.00008331553,0.0009868505,0.00022461225,0.00008441142,0.000019899842,0.00006629277,0.0000023949804],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000074399377,0.000051442967,0.0033282258,0.0000043212112,0.00005732681,5.699751e-8,0.00013900756,0.00014704044,0.9951846,0.000015910438,0.00022920314,0.0008354461],"study_design_scores_gemma":[0.00017747702,0.00015191198,0.0825357,0.0000049718387,0.00007259982,0.000008967085,0.00016787114,0.006173224,0.90851146,0.000050557934,0.0021054328,0.00003981674],"about_ca_topic_score_codex":0.00001931084,"about_ca_topic_score_gemma":0.000003392442,"teacher_disagreement_score":0.08667311,"about_ca_system_score_codex":0.0000170268,"about_ca_system_score_gemma":0.00007557209,"threshold_uncertainty_score":0.25392428},"labels":[],"label_agreement":null},{"id":"W1961668975","doi":"10.1371/journal.pone.0126420","title":"A Multilaboratory Comparison of Calibration Accuracy and the Performance of External References in Analytical Ultracentrifugation","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"National Institute of Biomedical Imaging and Bioengineering; National Heart, Lung, and Blood Institute; National Institute of Diabetes and Digestive and Kidney Diseases; Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie; National Institutes of Health; French Infrastructure for Integrated Structural Biology; Centre National de la Recherche Scientifique; National Research Foundation of Korea; Agence Nationale de la Recherche; Max-Planck-Gesellschaft; Deutsche Forschungsgemeinschaft; National Cancer Institute; National Research Foundation; European Regional Development Fund; European Commission; National Institute of General Medical Sciences; University of Utah; National Science Foundation","keywords":"Calibration; Standard deviation; Accuracy and precision; Magnification; Analytical Chemistry (journal); Analytical Ultracentrifugation; Range (aeronautics); Calibration curve; Reproducibility; Chemistry; Chromatography; Mathematics; Statistics; Optics; Materials science; Physics; Ultracentrifuge; Detection limit","score_opus":0.06819979971993181,"score_gpt":0.2960940549171755,"score_spread":0.22789425519724368,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1961668975","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986798,0.00084361987,0.00016908297,0.000093260765,0.000004691297,0.0001525188,0.000004595766,0.0000013911568,0.00005100872],"genre_scores_gemma":[0.9993671,0.00010840709,0.00046932785,0.000010260772,0.000011856342,0.0000094956495,0.000012156126,0.0000015210031,0.000009864399],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99948376,0.000085413216,0.00019322758,0.00008207845,0.00011351312,0.000041978397],"domain_scores_gemma":[0.99962115,0.000023556038,0.00010049671,0.00011714298,0.00011543833,0.000022188931],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030313848,0.000034206398,0.00010549692,0.0000146572465,0.000010097361,0.0000041410167,0.000056674697,0.000040075898,0.0000025088075],"category_scores_gemma":[0.00041192555,0.000024684496,0.000008959049,0.000056368684,0.00012063738,0.000006314276,0.000014735085,0.000041707994,2.1241716e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006178249,0.00056160457,0.49590957,0.000066162334,0.000016553613,2.8589128e-8,0.00048837723,0.000041317322,0.50095195,0.00038250504,0.0000047070275,0.0009593793],"study_design_scores_gemma":[0.00092162116,0.000121358615,0.07446656,0.000030754203,0.000013541537,1.05125025e-7,0.0001572355,0.04943452,0.874761,0.000037187154,0.000018981074,0.00003715199],"about_ca_topic_score_codex":0.000016693326,"about_ca_topic_score_gemma":0.000013780084,"teacher_disagreement_score":0.42144302,"about_ca_system_score_codex":0.0000043766922,"about_ca_system_score_gemma":0.00004453607,"threshold_uncertainty_score":0.10066045},"labels":[],"label_agreement":null},{"id":"W1965539555","doi":"10.1016/j.biotechadv.2013.01.007","title":"Recent advances in bioprocessing application of membrane chromatography","year":2013,"lang":"en","type":"review","venue":"Biotechnology Advances","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":254,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Bioprocess; Chromatography; Membrane; Chemistry; Biomolecule; Membrane technology; Filtration (mathematics); Chemical engineering; Engineering; Biochemistry","score_opus":0.013927969120414364,"score_gpt":0.3119263838994471,"score_spread":0.2979984147790327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965539555","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006039461,0.996727,0.0017788821,0.00006911265,0.0000823462,0.00096698845,0.000031763753,0.000047440295,0.00023606137],"genre_scores_gemma":[0.0002758441,0.9967789,0.0020334409,0.000010825271,0.000034206092,0.0006283125,0.00019953343,0.000024802117,0.0000141288265],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982013,0.000083782106,0.000684689,0.00067933276,0.00010408388,0.00024678],"domain_scores_gemma":[0.9985068,0.000023150109,0.00063178403,0.0007224354,0.00008037437,0.000035450837],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019940286,0.00031165805,0.00081911753,0.0002999296,0.000044412398,0.0000071233026,0.0005231898,0.0009845396,0.000012357713],"category_scores_gemma":[0.00016356842,0.00026483875,0.00016481135,0.00070821407,0.0004505423,0.000015916661,0.00010400885,0.00025259718,0.00001126572],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000061215633,0.000072948904,0.000023831279,0.0035734407,0.000017504548,2.5092552e-7,0.0000019244058,9.766711e-7,0.0023492463,0.00030844912,0.0000029755777,0.99364233],"study_design_scores_gemma":[0.000115528244,0.00006269722,0.0000033749072,0.0006129947,0.000029267172,0.000008906507,0.00001703314,0.0000026658831,0.01831994,0.0002987419,0.9802821,0.00024674597],"about_ca_topic_score_codex":0.000003144387,"about_ca_topic_score_gemma":0.0000344305,"teacher_disagreement_score":0.99339557,"about_ca_system_score_codex":0.000023602015,"about_ca_system_score_gemma":0.00010648558,"threshold_uncertainty_score":0.9999804},"labels":[],"label_agreement":null},{"id":"W1965744617","doi":"10.1016/j.chroma.2011.05.017","title":"Zonal rate model for stacked membrane chromatography. I: Characterizing solute dispersion under flow-through conditions","year":2011,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Dispersion (optics); Volumetric flow rate; Chromatography; Inlet; Membrane; Flow (mathematics); Elution; Stack (abstract data type); Residence time distribution; Mechanics; Analytical Chemistry (journal); Geology","score_opus":0.0364075868182998,"score_gpt":0.2703620733250873,"score_spread":0.23395448650678752,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965744617","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.79591244,0.00091421424,0.2017381,0.00030195332,0.0002273127,0.0003882072,0.00020468394,0.000019695366,0.00029336356],"genre_scores_gemma":[0.9758882,0.0005262239,0.022783779,0.0004454882,0.00013454037,0.0000386646,0.0001221587,0.000029139004,0.000031816286],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998535,0.000094755545,0.00060203363,0.0002728001,0.00019538836,0.00030006137],"domain_scores_gemma":[0.9986587,0.000021014986,0.00048545783,0.00033472737,0.00034229003,0.00015780496],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045457986,0.00021568152,0.00030323525,0.00016025294,0.00019942707,0.000033592503,0.0002858028,0.00017153246,0.0000657763],"category_scores_gemma":[0.000041428313,0.00019187825,0.00064986834,0.00020542329,0.00020466872,0.000047743157,0.000040687934,0.00014425207,0.0000019565348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006198608,0.0005021523,0.0008450766,0.000106130756,0.00045135885,0.000004213477,0.0005305341,0.00016744553,0.9937374,0.0016357932,0.0011539633,0.0002460436],"study_design_scores_gemma":[0.008241164,0.0019273849,0.044577025,0.00028566315,0.0004872864,0.0003555036,0.0007802302,0.017697057,0.8826509,0.021214444,0.020388758,0.0013945892],"about_ca_topic_score_codex":0.000003929329,"about_ca_topic_score_gemma":0.000005455316,"teacher_disagreement_score":0.17997573,"about_ca_system_score_codex":0.000012979227,"about_ca_system_score_gemma":0.00014328769,"threshold_uncertainty_score":0.78245676},"labels":[],"label_agreement":null},{"id":"W1967158487","doi":"10.1016/j.molbiopara.2010.04.008","title":"Characterization of the monomer–dimer equilibrium of recombinant histo-aspartic protease from Plasmodium falciparum","year":2010,"lang":"en","type":"article","venue":"Molecular and Biochemical Parasitology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Recombinant DNA; Biochemistry; Protease; Dissociation constant; Biology; Chaps; Enteropeptidase; Monomer; Size-exclusion chromatography; Dimer; Fusion protein; Peptide; Plasmodium falciparum; Chromatography; Chemistry; Enzyme; Organic chemistry","score_opus":0.007090087996041609,"score_gpt":0.24237019894461312,"score_spread":0.2352801109485715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967158487","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979179,0.0002661085,0.0005305254,0.00055519276,0.00027393713,0.00033354457,0.000038241837,0.0000057722386,0.00007876441],"genre_scores_gemma":[0.9993905,0.000009045262,0.00024723588,0.000102110534,0.00002740097,0.000040655486,0.00013310846,0.000010469748,0.000039496015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898016,0.0000950986,0.00031680646,0.0003384097,0.00010199166,0.00016755208],"domain_scores_gemma":[0.9991334,0.000011255244,0.00018206718,0.0005111683,0.000087700646,0.00007440513],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000114353614,0.00013289659,0.00021091792,0.0000217614,0.00002922747,0.0000049290497,0.00022628487,0.00028462367,0.0000200913],"category_scores_gemma":[0.00015807866,0.00010360045,0.000099147044,0.00007636997,0.00041639258,0.0000034843874,0.00013093083,0.00015892411,0.000001561058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012659069,0.000129215,0.015021139,0.000020540443,0.000027534157,4.7189397e-7,0.000020820127,3.789196e-7,0.9841795,0.0001528224,0.000030586943,0.00029043318],"study_design_scores_gemma":[0.00033923695,0.00007786703,0.037568696,0.0000055318924,0.000026351652,0.0000055753903,0.000004146649,0.00005073737,0.9600656,0.00031455822,0.0014316657,0.000110020905],"about_ca_topic_score_codex":0.000046360816,"about_ca_topic_score_gemma":0.0000055734813,"teacher_disagreement_score":0.024113854,"about_ca_system_score_codex":0.000004311292,"about_ca_system_score_gemma":0.000059053582,"threshold_uncertainty_score":0.42247036},"labels":[],"label_agreement":null},{"id":"W1968080795","doi":"10.1016/j.biotechadv.2011.07.013","title":"Disulfide bond formation and its impact on the biological activity and stability of recombinant therapeutic proteins produced by Escherichia coli expression system","year":2011,"lang":"en","type":"review","venue":"Biotechnology Advances","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Disulfide bond; Recombinant DNA; Chemistry; Escherichia coli; Biological activity; Biochemistry; Combinatorial chemistry; In vitro; Gene","score_opus":0.03831121246219597,"score_gpt":0.30770046516682464,"score_spread":0.26938925270462866,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968080795","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.18800437,0.8094859,0.0001798949,0.00009085107,0.000051518,0.0020478,0.00008898451,0.00003489132,0.000015749722],"genre_scores_gemma":[0.37849298,0.62108165,0.000046881632,0.00000401791,0.000007848048,0.00032765866,0.000026101792,0.000009720248,0.0000031256516],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982714,0.00045571243,0.00038382318,0.00060490903,0.00007360733,0.00021051498],"domain_scores_gemma":[0.9986373,0.0000779326,0.00055570947,0.0006294208,0.000054371958,0.00004526232],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00060676044,0.00033576525,0.0006716747,0.000043818065,0.00013915516,0.000010717527,0.0002753936,0.00081873144,0.0000036710514],"category_scores_gemma":[0.0003165618,0.00017390077,0.00011928843,0.00012723912,0.0003814225,0.000014416153,0.00015687123,0.00032456845,0.0000011171938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021661242,0.00022823387,0.00003475644,0.003844388,0.00006766583,2.4305282e-7,0.000021390164,1.6539868e-8,0.5216263,0.0011345148,0.000013822024,0.47281206],"study_design_scores_gemma":[0.00016110831,0.0008537473,0.00008740354,0.0007034712,0.00004874751,0.000009393641,0.000050007347,0.0000041254134,0.80868864,0.00011527493,0.18901372,0.00026436796],"about_ca_topic_score_codex":0.000004838107,"about_ca_topic_score_gemma":0.0000025146371,"teacher_disagreement_score":0.47254768,"about_ca_system_score_codex":0.00004179456,"about_ca_system_score_gemma":0.00006543997,"threshold_uncertainty_score":0.70914674},"labels":[],"label_agreement":null},{"id":"W1968444923","doi":"10.1016/j.biologicals.2010.07.005","title":"Excipient exchange in the comparison of preparations of the same biologic made by different manufacturing processes: An exploratory study with recombinant human growth hormone (rhGH)","year":2010,"lang":"en","type":"article","venue":"Biologicals","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Excipient; Chemistry; Innovator; Drug; Human growth hormone; Mannitol; Pharmacology; Chromatography; Biochemical engineering; Biochemistry; Hormone; Growth hormone; Medicine; Business; Entrepreneurship; Engineering","score_opus":0.03874264423928938,"score_gpt":0.30944956827301373,"score_spread":0.27070692403372437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968444923","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99812174,0.00048572724,0.000057820438,0.00011682978,0.000033436187,0.0010941306,0.000032327876,0.000008362521,0.00004961637],"genre_scores_gemma":[0.9994163,0.00005600346,0.000043536133,0.00003892286,0.000018425517,0.00033335856,0.000070711,0.0000049018477,0.000017852662],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99860835,0.0004282745,0.00036212758,0.00033122397,0.00011650425,0.00015349397],"domain_scores_gemma":[0.99903536,0.00003713425,0.0002506869,0.00056376006,0.0000797533,0.000033328433],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051116827,0.00014619513,0.00023110874,0.000021140298,0.000105723615,0.00001112626,0.0005051359,0.00013074398,0.000012600519],"category_scores_gemma":[0.00012632067,0.00006330024,0.000042361677,0.00009650319,0.00025408427,0.0000053643835,0.00010623214,0.00015813022,3.822431e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011241859,0.0025979627,0.116526924,0.00002739014,0.00001748847,1.5080566e-7,0.0011412777,0.0000018212188,0.879198,0.00008048001,0.00007128664,0.00022477307],"study_design_scores_gemma":[0.0004714945,0.0031672425,0.42825687,0.000007458756,0.000012274977,9.961258e-7,0.0027819348,0.000002691169,0.56428313,0.00034825143,0.00053231645,0.00013534885],"about_ca_topic_score_codex":0.000022431605,"about_ca_topic_score_gemma":0.0005672409,"teacher_disagreement_score":0.31491488,"about_ca_system_score_codex":0.000006995208,"about_ca_system_score_gemma":0.000023303503,"threshold_uncertainty_score":0.2581309},"labels":[],"label_agreement":null},{"id":"W1969418183","doi":"10.1016/j.jbiotec.2008.07.309","title":"Stability improvement of a therapeutic protein by reducing agent pretreatment","year":2008,"lang":"en","type":"article","venue":"Journal of Biotechnology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Chemistry; Pharmacology; Medicine","score_opus":0.015944474656963484,"score_gpt":0.24044929332473952,"score_spread":0.22450481866777605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1969418183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910392,0.0031941233,0.004345983,0.0009467764,0.000056457196,0.00034513333,0.0000139533195,0.0000073814226,0.0000509691],"genre_scores_gemma":[0.99814534,0.0005162295,0.0011810756,0.000038879694,0.000023727924,0.000016020653,0.00000465809,0.00000787171,0.00006618524],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989462,0.000056933626,0.00050316966,0.0001907377,0.00014942195,0.00015354661],"domain_scores_gemma":[0.9989646,0.000005889049,0.00044388286,0.00041029535,0.0001256411,0.000049654795],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003424764,0.00011058739,0.00021829104,0.00005674051,0.00004693608,0.0000026640337,0.00022569142,0.00023970625,0.000027514927],"category_scores_gemma":[0.000103568615,0.00008815901,0.00012433564,0.00009407327,0.00024488845,0.0000037471518,0.0000569053,0.00015580702,8.391829e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014527263,0.0003907072,0.0006000122,0.000018905655,0.000071928385,0.0000024154037,0.000053512045,0.000001699964,0.9850923,0.000050478204,0.00010914418,0.013463662],"study_design_scores_gemma":[0.0005405645,0.0019051862,0.00082746893,0.00000980744,0.000012852287,0.00005554582,0.00007632793,0.000005072813,0.9890115,0.00015542103,0.0073251603,0.000075091375],"about_ca_topic_score_codex":0.000017625534,"about_ca_topic_score_gemma":0.0000029623513,"teacher_disagreement_score":0.013388571,"about_ca_system_score_codex":0.000059691796,"about_ca_system_score_gemma":0.00014008694,"threshold_uncertainty_score":0.359502},"labels":[],"label_agreement":null},{"id":"W1971910683","doi":"10.1159/000230792","title":"Effect of Absorption of IgG with Insolubilized Antiserum on Reaginic Activity of DEAE-Serum Fractions","year":2009,"lang":"en","type":"article","venue":"International Archives of Allergy and Applied Immunology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Antiserum; Immunology; Absorption (acoustics); Chemistry; Immune sera; Antibody; Medicine; Materials science","score_opus":0.004213558183026952,"score_gpt":0.2406533229540168,"score_spread":0.23643976477098985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971910683","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939047,0.000108113585,0.0015940263,0.00018756415,0.000031052947,0.00013983953,0.000030241083,0.0000032437588,0.0040011983],"genre_scores_gemma":[0.9991507,0.00040892902,0.0003306117,0.0000133849,0.000009661672,0.000009566697,0.000034373657,0.000003794154,0.000038995782],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994118,0.00006375079,0.00021410732,0.00016828431,0.000074219766,0.000067798865],"domain_scores_gemma":[0.9994119,0.000081606995,0.00025527476,0.0001969123,0.00004040437,0.000013901685],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000900468,0.00008410335,0.00019153184,0.00007402197,0.00001727509,0.0000011487425,0.00013654042,0.0000644021,0.00001435198],"category_scores_gemma":[0.000037107235,0.000070074326,0.000054026856,0.000034611327,0.00027211627,0.0000038622306,0.000035404748,0.00007322297,2.4593882e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0045957104,0.0002622679,0.00041744186,0.000014950174,0.00023433726,8.273386e-8,0.00004380178,0.00005175018,0.9396509,0.004804323,0.0000013464792,0.049923077],"study_design_scores_gemma":[0.000996788,0.0015873485,0.17295362,0.000019715533,0.000006514206,0.0000020037571,0.000012016083,0.000044133358,0.82318014,0.0007445005,0.00040522678,0.000047988247],"about_ca_topic_score_codex":0.000017703784,"about_ca_topic_score_gemma":0.000009086841,"teacher_disagreement_score":0.17253618,"about_ca_system_score_codex":0.0000027489368,"about_ca_system_score_gemma":0.000024418521,"threshold_uncertainty_score":0.2857548},"labels":[],"label_agreement":null},{"id":"W1971973909","doi":"10.1002/jps.23639","title":"A Pulsed Tangential-Flow Ultrafiltration Technique for Studying Protein-Drug Binding","year":2013,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canada Research Chairs; McMaster University","keywords":"Ultrafiltration (renal); Chemistry; Drug; Flow (mathematics); Chromatography; Biophysics; Materials science; Mechanics; Pharmacology; Physics; Medicine; Biology","score_opus":0.049515278708328093,"score_gpt":0.35434271175881066,"score_spread":0.30482743305048254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971973909","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90233505,0.00061186944,0.09252422,0.0022940538,0.00020164977,0.0016488547,0.0000075249986,0.0000078752255,0.00036890068],"genre_scores_gemma":[0.9843977,0.000033738004,0.015076858,0.00011385132,0.00017545202,0.00012126322,0.0000021201345,0.0000043452333,0.00007463699],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998999,0.000094382296,0.00031431142,0.00016693053,0.00023398016,0.00019140667],"domain_scores_gemma":[0.9993784,0.000027503564,0.00017458128,0.000077035496,0.00022262745,0.00011986365],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014624045,0.00007944698,0.000103263854,0.000052747037,0.00017820839,0.00008250924,0.0002602412,0.000049532184,0.0000939489],"category_scores_gemma":[0.000284195,0.000058351838,0.000094680756,0.00014228439,0.00016784068,0.00002934809,0.000023512246,0.00010077043,0.0000034498316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031015185,0.000077041856,0.0005401243,0.000015848338,0.00001190671,2.768121e-7,0.000026053724,0.000022026836,0.99193925,0.00006650509,0.00021221141,0.007057748],"study_design_scores_gemma":[0.00036760597,0.00025264506,0.00034770937,0.00001652491,0.000012166733,0.000016007889,0.00009889135,0.00080022385,0.988993,0.00048992346,0.008514568,0.00009072703],"about_ca_topic_score_codex":0.0000024581736,"about_ca_topic_score_gemma":0.0000012255495,"teacher_disagreement_score":0.082062684,"about_ca_system_score_codex":0.000018355586,"about_ca_system_score_gemma":0.00011341545,"threshold_uncertainty_score":0.23795189},"labels":[],"label_agreement":null},{"id":"W1972171258","doi":"10.1016/j.jchromb.2012.05.039","title":"Simultaneous clarification of Escherichia coli culture and purification of extracellularly produced penicillin G acylase using tangential flow filtration and anion-exchange membrane chromatography (TFF-AEMC)","year":2012,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Natrix Separations (Canada); University of Waterloo","funders":"","keywords":"Chemistry; Chromatography; Recombinant DNA; Cross-flow filtration; Membrane; Escherichia coli; Size-exclusion chromatography; Downstream processing; Ion chromatography; Bioreactor; Ion exchange; Protein purification; Affinity chromatography; Microfiltration; Penicillin amidase; Filtration (mathematics); Biochemistry; Enzyme; Ion; Organic chemistry","score_opus":0.013192374487467148,"score_gpt":0.24671384423845094,"score_spread":0.23352146975098378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972171258","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9742423,0.017929373,0.0071649454,0.000055599376,0.00011790709,0.00041757795,0.000041019655,0.000006412447,0.000024848949],"genre_scores_gemma":[0.98622215,0.0019545457,0.011547195,0.000015432066,0.00016991694,0.000007987677,0.00005938952,0.000017214088,0.0000061884366],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983904,0.00019862918,0.0007116923,0.00023022326,0.0002854344,0.00018367368],"domain_scores_gemma":[0.9980246,0.000024882982,0.0009938428,0.00030929246,0.00049886113,0.00014856181],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00077831745,0.00018610984,0.00031604397,0.0001888719,0.00008835645,0.000027847871,0.00013919944,0.0002479496,0.000014323736],"category_scores_gemma":[0.00015909919,0.0001683749,0.00017520541,0.00034109957,0.00021764015,0.00006386424,0.000025011857,0.00015012985,1.5649752e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019685367,0.0003271619,0.0071521285,0.00026197452,0.00011507907,6.7239006e-7,0.00058541907,0.000028374918,0.98961943,0.00005413166,0.000021619326,0.001637172],"study_design_scores_gemma":[0.00084007287,0.000379679,0.019411614,0.000057110352,0.00015376849,0.00007760279,0.00025378863,0.00078373874,0.97581214,0.00003868565,0.0020010495,0.00019075726],"about_ca_topic_score_codex":0.000012047812,"about_ca_topic_score_gemma":0.0000041707412,"teacher_disagreement_score":0.015974827,"about_ca_system_score_codex":0.000009823532,"about_ca_system_score_gemma":0.000066910914,"threshold_uncertainty_score":0.6866129},"labels":[],"label_agreement":null},{"id":"W1973076966","doi":"10.1159/000228051","title":"Quantitative Studies on the Production of Precipitating Antibodies in Rabbits with and without DCA Treatment","year":2009,"lang":"en","type":"article","venue":"International Archives of Allergy and Applied Immunology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Immunology; Antibody; Medicine; Biology","score_opus":0.01948861189482371,"score_gpt":0.2858829156661012,"score_spread":0.2663943037712775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973076966","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962074,0.0010950932,0.00006867977,0.0010322994,0.000023892428,0.00014184679,0.000003061507,0.0000017953453,0.001425941],"genre_scores_gemma":[0.9970233,0.0018492334,0.0010065931,0.00002186516,0.000008408867,0.00002111803,0.000008228591,0.0000020122643,0.000059261107],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995979,0.000036107125,0.00013427503,0.00014823601,0.0000353999,0.00004809676],"domain_scores_gemma":[0.99973446,0.000057416568,0.0000953528,0.00007916669,0.000028164173,0.0000054523957],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000586452,0.00006475283,0.00010064526,0.000037476726,0.00002943598,0.0000020898624,0.000052363415,0.000018401017,7.752994e-7],"category_scores_gemma":[0.00007675346,0.000040106304,0.000011623896,0.000018075018,0.00031142394,0.0000022769216,0.000021567876,0.000032963533,6.9564926e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027296396,0.00022535048,0.0019867686,0.0000067829224,0.0005662287,1.3522727e-7,0.0038118912,0.00021046502,0.8762989,0.087750435,0.0000017028262,0.02641171],"study_design_scores_gemma":[0.0008726472,0.0022405626,0.26474446,0.00007678271,0.0000067531723,0.00000577435,0.0034508442,0.00008655798,0.71934193,0.008661148,0.0004047778,0.00010774151],"about_ca_topic_score_codex":0.000005968453,"about_ca_topic_score_gemma":0.000044798217,"teacher_disagreement_score":0.2627577,"about_ca_system_score_codex":0.0000029880634,"about_ca_system_score_gemma":0.0000111962645,"threshold_uncertainty_score":0.16354875},"labels":[],"label_agreement":null},{"id":"W1974771856","doi":"10.1016/j.chroma.2005.12.035","title":"Purification of humanized monoclonal antibody by hydrophobic interaction membrane chromatography","year":2006,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canada Research Chairs; McMaster University","keywords":"Chemistry; Monoclonal antibody; Chromatography; Bovine serum albumin; Membrane; Affinity chromatography; Antibody; Biochemistry","score_opus":0.00594779596957927,"score_gpt":0.25291917635755334,"score_spread":0.24697138038797406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974771856","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921141,0.0037967938,0.0029198085,0.00010539979,0.00015411442,0.00017831362,0.000026251253,0.00001048128,0.0006947304],"genre_scores_gemma":[0.99771494,0.00045043125,0.0014868939,0.000030617168,0.00013958618,0.0000075179587,0.00013203135,0.000017024557,0.00002095141],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99840313,0.00012333553,0.000807271,0.00020972505,0.00029446319,0.00016205596],"domain_scores_gemma":[0.99835354,0.000016715174,0.0009167501,0.00031594568,0.0003251955,0.00007186519],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039716606,0.00016574404,0.0002920872,0.00027441696,0.000067746136,0.000027654622,0.00025612966,0.00014310855,0.00004708494],"category_scores_gemma":[0.000026572568,0.00015172757,0.0004389159,0.00036260384,0.00015781609,0.00002432559,0.000020644507,0.00013888841,0.0000016167127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018770133,0.0004231226,0.007909334,0.00004931798,0.0001051298,0.0000014870889,0.000020039866,0.00001138127,0.9893684,0.00016073708,0.0014375325,0.0003258138],"study_design_scores_gemma":[0.0011553292,0.00037830835,0.02792216,0.000041160038,0.000049972903,0.00010111379,0.000051609997,0.000039626262,0.9468455,0.0003462904,0.022895072,0.00017390713],"about_ca_topic_score_codex":0.00003551277,"about_ca_topic_score_gemma":0.0000050661984,"teacher_disagreement_score":0.042522952,"about_ca_system_score_codex":0.000011524074,"about_ca_system_score_gemma":0.000059830963,"threshold_uncertainty_score":0.6187271},"labels":[],"label_agreement":null},{"id":"W1977097876","doi":"10.1136/bmj.g1976","title":"Patient commentary: my experience of gestational diabetes","year":2014,"lang":"en","type":"article","venue":"BMJ","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Newman Theological College","funders":"","keywords":"Isomerization; Chemistry; Monoclonal antibody; Deamidation; Chromatography; Recombinant DNA; Complementarity (molecular biology); Combinatorial chemistry; Computational biology; Antibody; Biochemistry; Enzyme; Catalysis; Biology","score_opus":0.00955049652138109,"score_gpt":0.26636539357263606,"score_spread":0.256814897051255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977097876","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964911,0.00008201406,0.0008255664,0.001413879,0.00004245425,0.000119752374,0.000012609362,0.0000032291723,0.0010094134],"genre_scores_gemma":[0.9976154,0.0000035077705,0.0012460718,0.0009554444,0.000037989557,0.00004726244,0.0000646207,0.0000025165382,0.000027198112],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99961394,0.000043490232,0.000116754636,0.00009998453,0.000066792236,0.000059044258],"domain_scores_gemma":[0.9996937,0.000009409215,0.00005047978,0.0001814442,0.000040837043,0.000024149613],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010055025,0.000035813653,0.000042366566,0.0000065437757,0.00002070629,0.0000027268009,0.000056087632,0.00002422466,0.000031673306],"category_scores_gemma":[0.00009523861,0.000033170847,0.000022187163,0.000018415842,0.000055364624,0.0000011710042,0.000027560154,0.000014914597,0.0000025466684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052383446,0.00024476487,0.15605703,0.00003393031,0.000025619194,1.1511216e-7,0.0006778622,0.00003292016,0.7839388,0.0015448228,0.019586334,0.03780539],"study_design_scores_gemma":[0.00022509918,0.00019142234,0.07006354,0.000005253728,0.0000022933307,3.6783106e-7,0.00013320836,0.00018586079,0.685587,0.00029654306,0.24321221,0.00009718821],"about_ca_topic_score_codex":0.000005757828,"about_ca_topic_score_gemma":0.000002420571,"teacher_disagreement_score":0.22362587,"about_ca_system_score_codex":0.0000029698422,"about_ca_system_score_gemma":0.000009696221,"threshold_uncertainty_score":0.1352668},"labels":[],"label_agreement":null},{"id":"W1979108956","doi":"10.1006/jcrs.2002.0500","title":"Stoichiometry of the Complex formed by Barley Limit Dextrinase with its Endogenous Inhibitor. Determination by Electrospray Time-of-flight Mass Spectrometry","year":2003,"lang":"en","type":"article","venue":"Journal of Cereal Science","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Chemistry; Electrospray ionization; Detection limit; Mass spectrometry; Chromatography; Bovine serum albumin","score_opus":0.011673329889960855,"score_gpt":0.23583441026139731,"score_spread":0.22416108037143645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979108956","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901576,0.0009705934,0.006369481,0.00011018146,0.000049664905,0.0001744239,0.00002460718,0.0000016901149,0.0021417802],"genre_scores_gemma":[0.998027,0.000071404575,0.0017421786,0.00003635382,0.000017809274,0.0000017341345,0.00000279466,0.000005404966,0.00009527812],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99866974,0.000094997995,0.0003515499,0.00016903954,0.00050322345,0.00021145096],"domain_scores_gemma":[0.99867815,0.000026219494,0.0005433113,0.00023648918,0.0004117152,0.00010409022],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00088636373,0.00009722347,0.00016367814,0.000090816946,0.00011246886,0.00001962522,0.0004314519,0.000057553196,0.000029472996],"category_scores_gemma":[0.00041352684,0.00006243892,0.00007308233,0.0006676275,0.00030441536,0.000024417322,0.000028541064,0.00011331003,6.133396e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006685074,0.00011562265,0.0027909633,0.000010731725,0.000009033462,5.0845534e-7,0.00002246096,0.0000020555105,0.9961183,0.000067218934,0.00012343262,0.00067279395],"study_design_scores_gemma":[0.00040934628,0.0007458567,0.005314246,0.000009483341,0.000012069132,0.0000795887,0.000022073784,0.000026634043,0.9913847,0.0000638499,0.0018566055,0.00007557878],"about_ca_topic_score_codex":0.00000300441,"about_ca_topic_score_gemma":0.0000028209013,"teacher_disagreement_score":0.007869464,"about_ca_system_score_codex":0.00006256849,"about_ca_system_score_gemma":0.0003667287,"threshold_uncertainty_score":0.25461853},"labels":[],"label_agreement":null},{"id":"W1979647083","doi":"10.1016/j.chroma.2010.09.044","title":"Ion-exchange chromatographic protein refolding","year":2010,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Indigenous and Northern Affairs Canada","keywords":"Chemistry; Chromatography; Ion exchange; Adsorption; Saturation (graph theory); Yield (engineering); Ion chromatography; Native state; Ion; Biochemistry; Organic chemistry","score_opus":0.006269020624929275,"score_gpt":0.2369501594536893,"score_spread":0.23068113882876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979647083","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955941,0.0018173254,0.0006149358,0.00029002439,0.00032543336,0.00021934412,0.0000062157355,0.000014682767,0.0011179573],"genre_scores_gemma":[0.99622524,0.00015719535,0.0030347663,0.000086042826,0.00042145775,0.00001808183,0.0000060273223,0.000018740691,0.000032444117],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880385,0.0000737782,0.0004533354,0.00019550668,0.00026009345,0.00021342469],"domain_scores_gemma":[0.99872875,0.000007987153,0.00041303088,0.00042050437,0.00025999264,0.00016974282],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000712913,0.00015215036,0.00020435997,0.0002458544,0.000097282995,0.000039740065,0.00034744394,0.00018829784,0.00009182722],"category_scores_gemma":[0.00013440565,0.00012791647,0.00036879483,0.00033743875,0.00016056196,0.00001394332,0.000045514604,0.00030971918,0.000003476457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056030058,0.0001293177,0.006650407,0.00003955536,0.000069225265,0.000006126472,0.000037705915,3.4056154e-7,0.98986953,0.0004657193,0.00048802642,0.0021880276],"study_design_scores_gemma":[0.0011749652,0.000569505,0.037326943,0.00006570881,0.000032460815,0.00041857967,0.000070034745,0.000007810043,0.75155395,0.0013274329,0.20712735,0.00032523953],"about_ca_topic_score_codex":0.000004215549,"about_ca_topic_score_gemma":0.000017396726,"teacher_disagreement_score":0.23831555,"about_ca_system_score_codex":0.0000046234504,"about_ca_system_score_gemma":0.000091005066,"threshold_uncertainty_score":0.52162826},"labels":[],"label_agreement":null},{"id":"W1981759825","doi":"10.1016/j.clinbiochem.2014.06.051","title":"Impact of a shortened centrifugation protocol for common chemistry and immunology testing on different automation platforms","year":2014,"lang":"en","type":"article","venue":"Clinical Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Capital District Health Authority; Dalhousie University; Health Canada","funders":"","keywords":"Protocol (science); Centrifugation; Automation; Immunology; Computer science; Chemistry; Computational biology; Medicine; Chromatography; Biology; Engineering; Pathology; Mechanical engineering","score_opus":0.04386064467523835,"score_gpt":0.3909181545600538,"score_spread":0.34705750988481543,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981759825","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98871243,0.00001237124,0.0011757243,0.00003660309,0.000020893836,0.00966534,0.000033659297,0.000023000646,0.00031997057],"genre_scores_gemma":[0.98837686,0.0000026489256,0.0006724225,0.000029992192,0.00014231724,0.01050328,0.00022240481,0.000012957,0.000037135156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986885,0.000037069778,0.000584737,0.00042262548,0.00008804948,0.00017901242],"domain_scores_gemma":[0.998768,0.0001820393,0.00032196115,0.00047723524,0.00015313848,0.000097664655],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004429644,0.00017101325,0.00026063828,0.000008663252,0.00006274412,0.000013051276,0.00015271922,0.00036844355,0.000010764024],"category_scores_gemma":[0.0019721803,0.00013519505,0.00016749318,0.000046441502,0.000192445,0.0000032698824,0.000062786174,0.00013042614,6.851072e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007441919,0.00043360138,0.068871,0.00021321043,0.00006187392,6.971322e-8,0.0000040674154,0.000007676108,0.8959126,0.000027907487,0.00007668508,0.033647154],"study_design_scores_gemma":[0.0022577627,0.0010664018,0.15532695,0.00005040727,0.000012474219,0.0000038825992,0.0000070085125,0.0022673574,0.83793736,0.0005107588,0.00036694086,0.0001927124],"about_ca_topic_score_codex":0.0000024581698,"about_ca_topic_score_gemma":5.651718e-7,"teacher_disagreement_score":0.08645595,"about_ca_system_score_codex":0.000026309912,"about_ca_system_score_gemma":0.000065307875,"threshold_uncertainty_score":0.5513094},"labels":[],"label_agreement":null},{"id":"W1982077060","doi":"10.1016/j.ijpharm.2005.03.022","title":"Development and application of high throughput plasma stability assay for drug discovery","year":2005,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":190,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Chemistry; In vivo; Drug discovery; Chromatography; Prodrug; Clearance; Substrate (aquarium); Enzyme; Human plasma; Pharmacokinetics; Plasma; Pharmacology; Biochemistry; Biology","score_opus":0.025819967920572263,"score_gpt":0.3381631802591134,"score_spread":0.3123432123385411,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982077060","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8867851,0.00042226227,0.11129555,0.0010699398,0.00017348026,0.00014916137,0.000045747438,0.0000018841465,0.000056909368],"genre_scores_gemma":[0.97455466,0.00015256197,0.024850879,0.00012274996,0.00023055187,0.0000094917605,0.000029901648,0.000005641101,0.000043562904],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919695,0.000033377575,0.0003906752,0.00011501914,0.00019569646,0.00006830559],"domain_scores_gemma":[0.9990855,0.000037832724,0.00029806411,0.00008838261,0.0004466243,0.00004362778],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061756023,0.00006808863,0.00009916399,0.000030853174,0.000024595494,0.000017100037,0.0001959359,0.00003885462,0.0000060291463],"category_scores_gemma":[0.000110230045,0.00006147184,0.000052839507,0.000020694124,0.000059179154,0.000019574547,0.000049323993,0.000062847306,4.7193768e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007443898,0.00042974122,0.005744079,0.000046977715,0.00026964064,4.5819488e-7,0.000426078,0.0003100554,0.74960095,0.0023833187,0.00012978936,0.23991452],"study_design_scores_gemma":[0.0007651316,0.000021083584,0.0014377184,0.000005387118,0.000012945937,0.000010161639,0.00005465338,0.0007540468,0.8178213,0.00020408363,0.17885722,0.000056260575],"about_ca_topic_score_codex":0.0000019381173,"about_ca_topic_score_gemma":0.000012568904,"teacher_disagreement_score":0.23985825,"about_ca_system_score_codex":0.00004649449,"about_ca_system_score_gemma":0.00011209989,"threshold_uncertainty_score":0.25067487},"labels":[],"label_agreement":null},{"id":"W1984230040","doi":"10.1016/j.ab.2009.10.047","title":"Enrichment of serum low-molecular-weight proteins using C18 absorbent under urea/dithiothreitol denatured environment","year":2009,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China; Canadian Institute for Theoretical Astrophysics","keywords":"Dithiothreitol; Urea; Chemistry; Chromatography; Biochemistry; Enzyme","score_opus":0.007703113656184893,"score_gpt":0.2542636534913867,"score_spread":0.2465605398352018,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984230040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9860464,0.0017252787,0.009333274,0.0009447647,0.000040304305,0.00040801376,0.000055939447,0.000019512161,0.0014265195],"genre_scores_gemma":[0.99695337,0.00007178471,0.0019874398,0.00043948874,0.00011196683,0.000013299301,0.00009001866,0.000016482918,0.00031615727],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99816793,0.000048743255,0.00043961202,0.00062839827,0.0003652981,0.0003500147],"domain_scores_gemma":[0.9986961,0.000008067642,0.00015562307,0.00083886384,0.00008200741,0.00021934451],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018783641,0.0002693519,0.00025883495,0.000031988326,0.00006384122,0.000020313328,0.0002993688,0.00037094796,0.00015443566],"category_scores_gemma":[0.000077302495,0.00025241915,0.00022284538,0.00011991384,0.00018080186,0.000004477328,0.00009454833,0.00019219363,0.000009031308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006394869,0.00044431014,0.00047673704,0.000048298287,0.00008626175,0.000005626512,0.0000070989618,0.00011360391,0.9972297,0.0005164019,0.000078932244,0.00092908536],"study_design_scores_gemma":[0.0004705682,0.00013171369,0.0033604896,0.000027736187,0.000058728387,0.000010038827,0.000022706212,0.00050990155,0.9935319,0.00048184066,0.0011013038,0.0002930779],"about_ca_topic_score_codex":0.0000041055614,"about_ca_topic_score_gemma":4.550584e-7,"teacher_disagreement_score":0.010906968,"about_ca_system_score_codex":0.000087025204,"about_ca_system_score_gemma":0.0001351132,"threshold_uncertainty_score":0.9999928},"labels":[],"label_agreement":null},{"id":"W1985285310","doi":"10.1002/bit.21046","title":"Purification of an elastin‐like fusion protein by microfiltration","year":2006,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"U.S. Public Health Service","keywords":"Microfiltration; Chromatography; Lysis; Chemistry; Membrane; Fusion protein; Fusion; Protein purification; Recombinant DNA; Biochemistry","score_opus":0.0034952251685365595,"score_gpt":0.19102499452393754,"score_spread":0.18752976935540097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985285310","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97324955,0.0014393256,0.024678618,0.00028069358,0.000029624334,0.00020797584,0.000019044273,0.00004897364,0.000046205078],"genre_scores_gemma":[0.994951,0.000058621714,0.0046586953,0.000007326947,0.000027252396,0.000024846997,0.00017831387,0.000007436519,0.000086481064],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99944264,0.000016015743,0.0001639624,0.00022899978,0.00004241012,0.000105965715],"domain_scores_gemma":[0.99966145,0.0000017950815,0.000058507616,0.00022654027,0.000030645253,0.000021053032],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001078934,0.00008775136,0.00007532284,0.000049761475,0.000043060805,0.000006610943,0.00008615586,0.00029664312,0.0000033911867],"category_scores_gemma":[0.000016161306,0.000086692875,0.000018218076,0.000083091734,0.00009582798,0.000005731035,0.000025442187,0.000064438376,8.168835e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017939701,0.0000496304,0.00017677958,0.000018259389,0.0000044726735,1.1842003e-7,0.0000027421238,0.000009526903,0.99528307,0.0009412157,0.000033611654,0.0034626238],"study_design_scores_gemma":[0.00015812913,0.00014140618,0.0018053737,0.000005269567,0.0000034401405,0.0000055477044,0.000014093138,0.00037073003,0.98623914,0.00007073504,0.011091342,0.000094822855],"about_ca_topic_score_codex":0.000017119337,"about_ca_topic_score_gemma":0.000006641327,"teacher_disagreement_score":0.021701485,"about_ca_system_score_codex":0.000005404133,"about_ca_system_score_gemma":0.000010516755,"threshold_uncertainty_score":0.35352328},"labels":[],"label_agreement":null},{"id":"W1985301694","doi":"10.1016/j.pep.2008.02.015","title":"Enhancing the specificity of the enterokinase cleavage reaction to promote efficient cleavage of a fusion tag","year":2008,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences","keywords":"Cleavage (geology); Proteolysis; Chemistry; Zipper; Enteropeptidase; Leucine zipper; Biochemistry; Exopeptidase; Fusion protein; Biology; Peptide sequence; Peptide; Recombinant DNA; Enzyme; Gene","score_opus":0.012940122507638948,"score_gpt":0.23702541186155174,"score_spread":0.22408528935391278,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985301694","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921566,0.0003317559,0.0051624365,0.00049229234,0.00006376951,0.0014048297,0.000015367104,0.000010028589,0.00036290256],"genre_scores_gemma":[0.9986747,0.000078011835,0.0007943084,0.00004299099,0.0000462535,0.00012448966,0.000013624191,0.000009871037,0.00021574555],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987121,0.00022140105,0.00038035645,0.0003180979,0.00024325788,0.00012477058],"domain_scores_gemma":[0.9988238,0.000012359945,0.00029345346,0.0006911173,0.000121124714,0.00005810553],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055467454,0.00011696912,0.00012189251,0.000034508153,0.00024326942,0.000008140629,0.00023022588,0.000101772304,0.0000062160875],"category_scores_gemma":[0.00025216048,0.00007225824,0.00007061315,0.00015700498,0.00015115223,0.000006231689,0.00012199019,0.00010944548,0.0000023949804],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001841995,0.00014880058,0.000303291,0.000041335355,0.0000035688881,9.895876e-8,0.00056024693,0.0000060043576,0.9950213,0.00009829627,0.00011134562,0.0035215267],"study_design_scores_gemma":[0.00020817993,0.00009841715,0.025290156,0.000074349344,0.0000045453235,0.0000042630036,0.00013307361,0.000037135876,0.9664391,0.000036678375,0.007596755,0.00007730897],"about_ca_topic_score_codex":0.000025598873,"about_ca_topic_score_gemma":0.0000063228044,"teacher_disagreement_score":0.028582148,"about_ca_system_score_codex":0.000013907303,"about_ca_system_score_gemma":0.00004092256,"threshold_uncertainty_score":0.29466054},"labels":[],"label_agreement":null},{"id":"W1986185508","doi":"10.1016/j.jim.2005.05.013","title":"Purification and separation of hydrophobic serum amyloid a precursor isoforms by a one-step preparative method","year":2005,"lang":"en","type":"article","venue":"Journal of Immunological Methods","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Gene isoform; Chemistry; Chromatography; Amyloid (mycology); Separation method; Biochemistry; Separation (statistics); Computer science","score_opus":0.02075672754591253,"score_gpt":0.3780964679364615,"score_spread":0.357339740390549,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986185508","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6384579,0.011954892,0.3481449,0.00063396443,0.000054668562,0.00029800847,0.000017764993,0.0000063629004,0.00043155358],"genre_scores_gemma":[0.48510614,0.0009661621,0.5135617,0.000064614534,0.00004849617,0.000016204793,0.000008298103,0.0000063117113,0.00022204223],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978449,0.00095908355,0.00067249604,0.00022889556,0.0001457484,0.00014889597],"domain_scores_gemma":[0.9985709,0.00010958395,0.0006963024,0.00026071307,0.00029511753,0.00006733662],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022296943,0.00013776595,0.0003263506,0.000055356242,0.000058102738,0.000018590148,0.00020480475,0.00023830144,0.00003936133],"category_scores_gemma":[0.0006612705,0.00010158442,0.00012812625,0.00012021094,0.00014539198,0.000024625571,0.000057794005,0.00020961638,0.0000015217804],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040397045,0.00021957027,0.00011634312,0.000011506077,0.00008111575,1.1829288e-7,0.00013354454,0.000012085419,0.8538896,0.0001421651,0.00007731454,0.14491266],"study_design_scores_gemma":[0.00064344564,0.0013486422,0.006066791,0.00001458072,0.000037355956,0.000036498885,0.000107289445,0.00036713242,0.94965386,0.0006210931,0.0409758,0.00012747718],"about_ca_topic_score_codex":0.0000023406963,"about_ca_topic_score_gemma":0.000001056535,"teacher_disagreement_score":0.16541684,"about_ca_system_score_codex":0.000031888285,"about_ca_system_score_gemma":0.00006204931,"threshold_uncertainty_score":0.41424924},"labels":[],"label_agreement":null},{"id":"W1986577002","doi":"10.1007/s11120-009-9493-4","title":"Modification of a French pressure cell to improve microbial cell disruption","year":2009,"lang":"en","type":"article","venue":"Photosynthesis Research","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Stem cell; Ball valve; Chemistry; Biology; Cell biology; Mechanical engineering; Engineering","score_opus":0.029454039387470734,"score_gpt":0.32715687486862094,"score_spread":0.29770283548115023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986577002","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901119,0.00076081656,0.0013572432,0.0006260424,0.000034408316,0.0009862863,0.00010022346,0.000011851477,0.006011254],"genre_scores_gemma":[0.99710983,0.00010611495,0.00084381306,0.000049646656,0.00007191405,0.00007328556,0.000036300564,0.000010245812,0.0016988396],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984933,0.00024620842,0.00023421079,0.00044152775,0.00030016678,0.00028460214],"domain_scores_gemma":[0.9987582,0.000036349094,0.00006027955,0.0006899071,0.00033720402,0.00011808055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009087872,0.000101938575,0.0001229584,0.000100433776,0.00008417851,0.000026541476,0.0003441352,0.00014191397,0.00007934647],"category_scores_gemma":[0.00031147138,0.00009905047,0.00007350156,0.0002056697,0.00006739743,0.000004927407,0.00006637017,0.00013249507,0.00004248433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000123009,0.0003410589,0.00008382133,0.000048506507,0.000005174575,1.5220769e-7,0.00011388202,0.000013997128,0.991936,0.000018800567,0.0010200996,0.0062954524],"study_design_scores_gemma":[0.0001705048,0.00027755072,0.00333491,0.0000060218786,0.00000567382,3.1510785e-7,0.00003976133,0.00010980502,0.96548456,0.0001032121,0.030368729,0.000098959295],"about_ca_topic_score_codex":0.00010751786,"about_ca_topic_score_gemma":0.000013244781,"teacher_disagreement_score":0.029348629,"about_ca_system_score_codex":0.000019841722,"about_ca_system_score_gemma":0.000095724965,"threshold_uncertainty_score":0.40391612},"labels":[],"label_agreement":null},{"id":"W1986612337","doi":"10.1002/elps.201200663","title":"Development of glutaraldehyde‐crosslinked chymotrypsin and an in situ immobilized enzyme microreactor with peptide mapping by capillary electrophoresis","year":2013,"lang":"en","type":"article","venue":"Electrophoresis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Glutaraldehyde; Chemistry; Chymotrypsin; Chromatography; Capillary electrophoresis; Immobilized enzyme; Reagent; Substrate (aquarium); Myoglobin; Microreactor; Proteolytic enzymes; Casein; Peptide; Trypsin; Enzyme; Biochemistry; Organic chemistry; Catalysis","score_opus":0.006339809275612258,"score_gpt":0.21804343970966636,"score_spread":0.2117036304340541,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986612337","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99392724,0.0046968763,0.0004916352,0.000108691456,0.000009760968,0.00062448415,0.0000074942204,0.000016786424,0.00011703929],"genre_scores_gemma":[0.9893391,0.00052459125,0.00953576,0.00009082517,0.000026020474,0.00017830761,0.0001735368,0.000033474993,0.00009835763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981786,0.00012496585,0.00045328136,0.00059493224,0.00017938585,0.0004688579],"domain_scores_gemma":[0.9991068,0.000015769134,0.0001561735,0.00044710585,0.00012884998,0.00014525239],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023598428,0.00026766848,0.0003139354,0.00009786728,0.00009543823,0.000035421184,0.00022312615,0.00018319658,0.000041163243],"category_scores_gemma":[0.00005004732,0.00023532622,0.000047998252,0.00023809192,0.00015231992,0.000014769106,0.000056472265,0.00015128739,0.0000040340938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035355633,0.00017228251,0.002192239,0.000032707452,0.000052477568,0.0000010209633,0.00031270878,5.6888405e-7,0.9944014,0.000011519276,0.00028102112,0.0021885005],"study_design_scores_gemma":[0.00080504006,0.000312108,0.0480384,0.000014422682,0.000008032498,0.000007996991,0.00012997289,0.000015656304,0.94271976,0.00004366856,0.007607654,0.0002972987],"about_ca_topic_score_codex":0.0002302736,"about_ca_topic_score_gemma":0.00041752486,"teacher_disagreement_score":0.05168165,"about_ca_system_score_codex":0.000068961264,"about_ca_system_score_gemma":0.00022956402,"threshold_uncertainty_score":0.95963246},"labels":[],"label_agreement":null},{"id":"W1988530811","doi":"10.1016/s0005-2736(02)00397-8","title":"Stability of the lactose permease in detergent solutions","year":2002,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research; Health Canada; Deutsche Forschungsgemeinschaft","keywords":"Lactose permease; Permease; Glycerol; Chemistry; Biochemistry; Cytochrome; Lysozyme; Chromatography; Escherichia coli; Enzyme","score_opus":0.035384512167750654,"score_gpt":0.23883296614371605,"score_spread":0.2034484539759654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988530811","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954322,0.00043758712,0.000014816983,0.0028200725,0.00013292543,0.0005006712,0.0001951562,0.000021622667,0.00044492373],"genre_scores_gemma":[0.999087,0.000283552,0.000071438095,0.00024420998,0.00006606972,0.000060098027,0.000055618933,0.00001998603,0.00011205138],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981323,0.00030111612,0.00045185263,0.0005316997,0.00023465038,0.00034840536],"domain_scores_gemma":[0.9984872,0.000030829673,0.0001867693,0.0010913365,0.00009968559,0.00010422951],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030782763,0.00023900977,0.00023620049,0.000071210685,0.00012280804,0.000023852876,0.00052065484,0.00017445757,0.00010884574],"category_scores_gemma":[0.00017341247,0.00018361669,0.00026324342,0.00043758625,0.00045944942,0.000012705,0.0002252895,0.00014446702,0.000013579101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061376675,0.00067166233,0.00017616263,0.000060059854,0.000026136024,3.0225868e-7,0.0002057263,0.0000016669768,0.99817216,0.00008966042,0.00015778931,0.00037729525],"study_design_scores_gemma":[0.00045159756,0.000090994385,0.029287182,0.00001625711,0.000017706838,0.000002697644,0.00007536213,0.00020962239,0.9674392,0.000078247016,0.0021083206,0.00022283796],"about_ca_topic_score_codex":0.000057432906,"about_ca_topic_score_gemma":0.000092598915,"teacher_disagreement_score":0.030732987,"about_ca_system_score_codex":0.000032556938,"about_ca_system_score_gemma":0.00007276988,"threshold_uncertainty_score":0.74876714},"labels":[],"label_agreement":null},{"id":"W1988874452","doi":"10.1016/j.ejpb.2013.04.009","title":"Osmotic pressure driven protein release from viscous liquid, hydrophobic polymers based on 5-ethylene ketal ε-caprolactone: Potential and mechanism","year":2013,"lang":"en","type":"article","venue":"European Journal of Pharmaceutics and Biopharmaceutics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Caprolactone; Chemistry; Polymer; Osmotic pressure; Mechanism (biology); Ethylene; Chemical engineering; Organic chemistry; Biochemistry; Polymerization; Catalysis","score_opus":0.011825341184015662,"score_gpt":0.24952639077523497,"score_spread":0.23770104959121932,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988874452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908001,0.005162446,0.0018494627,0.0010299009,0.00029661917,0.0005820681,0.00006449074,0.000016552858,0.00019834982],"genre_scores_gemma":[0.9956687,0.0014898872,0.0011441534,0.0010804369,0.0003851733,0.000009215492,0.000024664198,0.000058947604,0.00013880314],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997639,0.0006373462,0.00059436925,0.00042643302,0.00035666433,0.0003461834],"domain_scores_gemma":[0.99847305,0.000023470158,0.00043044772,0.00031527795,0.0002254579,0.0005322735],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00063833344,0.00034273588,0.00028069734,0.00011196975,0.00016882234,0.00012455868,0.00032240167,0.000106422405,0.00020179685],"category_scores_gemma":[0.00006631851,0.00029604408,0.00014023669,0.00009413097,0.00022475676,0.000024760717,0.000155373,0.00052169745,0.000016156093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009443528,0.00024488344,0.00006925285,0.00007131527,0.00015609666,0.00007316281,0.00011636425,0.0001783772,0.99048895,0.000011500875,0.00006115721,0.007584566],"study_design_scores_gemma":[0.004805351,0.001708802,0.0008166499,0.00007830127,0.00037389927,0.00008675526,0.00019302496,0.031953946,0.9405557,0.00005431781,0.01883904,0.00053422723],"about_ca_topic_score_codex":0.0000055847645,"about_ca_topic_score_gemma":2.4968935e-7,"teacher_disagreement_score":0.049933285,"about_ca_system_score_codex":0.0000161778,"about_ca_system_score_gemma":0.00009265225,"threshold_uncertainty_score":0.99994916},"labels":[],"label_agreement":null},{"id":"W1989316273","doi":"10.1586/ecp.12.72","title":"Current issues in biowaivers and biosimilars","year":2013,"lang":"en","type":"article","venue":"Expert Review of Clinical Pharmacology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biosimilar; Medicine; Library science; Family medicine; Internal medicine","score_opus":0.04851537287578259,"score_gpt":0.48056864695647394,"score_spread":0.43205327408069133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989316273","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15736301,0.82368517,0.00004516738,0.016647091,0.001004227,0.0009093521,0.0000062867466,0.0000076420465,0.00033204583],"genre_scores_gemma":[0.14232819,0.8468283,0.0005631886,0.009805113,0.00030653377,0.0001184416,0.000017029826,0.000006084543,0.00002710773],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985276,0.00035567107,0.0006470655,0.00028463482,0.000060190367,0.00012488132],"domain_scores_gemma":[0.99944526,0.00005579484,0.00014228922,0.00018367895,0.00008401126,0.0000889511],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006572385,0.00009114349,0.00034226943,0.000020314068,0.00001286643,0.0000024505089,0.00014760917,0.00009062301,0.00048265187],"category_scores_gemma":[0.00042480996,0.00007445131,0.00009696609,0.000060731847,0.00023504783,0.000004331695,0.00008810149,0.000117297546,0.000017683169],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007642452,0.0006873738,0.024057532,0.0014624662,0.000055616016,0.0000012184364,0.000034626075,2.0187152e-7,0.07834568,0.000052322506,0.41204363,0.4831829],"study_design_scores_gemma":[0.0005518783,0.00013100379,0.019000461,0.00018685669,0.0000072058397,9.961066e-7,0.0000073485844,0.00001469807,0.012614651,0.000051595576,0.9673369,0.00009644064],"about_ca_topic_score_codex":0.000010682376,"about_ca_topic_score_gemma":0.0000018043224,"teacher_disagreement_score":0.55529326,"about_ca_system_score_codex":0.000003971867,"about_ca_system_score_gemma":0.000045924135,"threshold_uncertainty_score":0.52847},"labels":[],"label_agreement":null},{"id":"W1989999563","doi":"10.1021/bi9925571","title":"Deimination of Myelin Basic Protein. 2. Effect of Methylation of MBP on Its Deimination by Peptidylarginine Deiminase","year":2000,"lang":"en","type":"article","venue":"Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; Hospital for Sick Children","funders":"","keywords":"Citrullination; Myelin basic protein; Chemistry; Methylation; Citrulline; Biochemistry; Arginine; Myelin; Biology; Amino acid; Endocrinology; Central nervous system","score_opus":0.006832834466621089,"score_gpt":0.2539977809249244,"score_spread":0.24716494645830334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989999563","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967428,0.0010162602,0.00025793063,0.00006808062,0.00001707481,0.00046565259,0.00013600319,0.000009128901,0.0012870592],"genre_scores_gemma":[0.99821645,0.00006267921,0.0002720897,0.0000094566385,0.00003706104,0.00006747238,0.00056308595,0.000015095626,0.00075658364],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986925,0.00012637583,0.00045158144,0.00034083272,0.00025547936,0.00013323472],"domain_scores_gemma":[0.9989027,0.000037255337,0.00031746505,0.00044868528,0.00023851938,0.00005538129],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005177689,0.00017251786,0.00023254356,0.00004105363,0.000029315413,0.0000038430867,0.00017539537,0.0002443483,0.00015792991],"category_scores_gemma":[0.00047243238,0.00016782041,0.000117058145,0.0001502322,0.00010841262,0.000006800231,0.000021808264,0.00007660659,0.000003855506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049484335,0.0001990333,0.00024205858,0.00041061733,0.00002467384,1.5689434e-7,0.000027177864,0.000018634424,0.97174525,0.000019913212,0.00012068934,0.026696922],"study_design_scores_gemma":[0.0007716629,0.0006498162,0.0009482585,0.00006362766,0.000029393688,0.0000011587812,0.000015652757,0.0001677932,0.9965904,0.000014903766,0.0006135266,0.00013382566],"about_ca_topic_score_codex":0.000007903388,"about_ca_topic_score_gemma":7.3970597e-7,"teacher_disagreement_score":0.026563097,"about_ca_system_score_codex":0.000023275215,"about_ca_system_score_gemma":0.000062019826,"threshold_uncertainty_score":0.6843518},"labels":[],"label_agreement":null},{"id":"W1991348882","doi":"10.1016/j.chroma.2015.03.034","title":"Thermo-responsive adsorbent for size-selective protein adsorption","year":2015,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"University of Waterloo; Universiti Putra Malaysia; Canadian Bureau for International Education; Commonwealth Fund","keywords":"Chemistry; Adsorption; Methacrylate; Protein adsorption; Chromatography; Lower critical solution temperature; Agarose; Bovine serum albumin; Ethylene glycol; Polymer chemistry; Copolymer; Desorption; Polymer; Organic chemistry","score_opus":0.017649601814942323,"score_gpt":0.27316428061278103,"score_spread":0.25551467879783873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991348882","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9873118,0.0018494226,0.009389192,0.00037154372,0.00011533292,0.0005742137,0.000017034637,0.0000073717897,0.00036408566],"genre_scores_gemma":[0.9962632,0.000029290259,0.0032763795,0.0000994239,0.00018938708,0.00005663159,0.0000058010914,0.000012491283,0.000067397974],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990933,0.00012553947,0.00031264438,0.00014318632,0.0001842101,0.00014110698],"domain_scores_gemma":[0.9985632,0.000024715753,0.00033668164,0.00018132309,0.00075692456,0.00013718655],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00064461405,0.0001058486,0.00015895952,0.0000758401,0.000033170614,0.00001925293,0.00015735003,0.00010395316,0.000007925304],"category_scores_gemma":[0.00065887754,0.00008675976,0.00025444673,0.00013961206,0.00006355315,0.000009060837,0.000017373757,0.00008609956,0.0000014737043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018309985,0.00021434108,0.00089853955,0.000022372154,0.00014561167,0.0000015142214,0.00018280461,0.000012506088,0.99176353,0.00032377552,0.0026949598,0.0019090595],"study_design_scores_gemma":[0.003018756,0.0027384905,0.010185732,0.000044382636,0.00004621883,0.000089967674,0.0003605306,0.000030129633,0.9074504,0.0057377378,0.0700562,0.00024149654],"about_ca_topic_score_codex":0.0000020728987,"about_ca_topic_score_gemma":0.000003556871,"teacher_disagreement_score":0.08431316,"about_ca_system_score_codex":0.00002150429,"about_ca_system_score_gemma":0.00024127227,"threshold_uncertainty_score":0.35379604},"labels":[],"label_agreement":null},{"id":"W1994325676","doi":"10.1039/c4mb00220b","title":"Renal protein reactivity and stability of antibiotic amphenicols: structure and affinity","year":2014,"lang":"en","type":"article","venue":"Molecular BioSystems","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Royal Society of Chemistry; Royal Society","keywords":"Reactivity (psychology); Antibiotics; Chemistry; Protein stability; Microbiology; Biochemistry; Biology; Medicine; Pathology","score_opus":0.007858789646993275,"score_gpt":0.2212132570944749,"score_spread":0.21335446744748163,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994325676","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995896,0.0008130107,0.0022019793,0.000093825125,0.000032497264,0.0006628842,0.000059880138,0.000013626335,0.00022632591],"genre_scores_gemma":[0.99903744,0.000010306956,0.0008302526,0.00002830891,0.000031723925,0.000010652308,0.000029695662,0.000013447565,0.000008195263],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985468,0.00039131806,0.00026599874,0.00047643163,0.00015074357,0.00016871955],"domain_scores_gemma":[0.9990361,0.000014873683,0.00015661266,0.0005865916,0.00010120438,0.0001046257],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000601274,0.00016539618,0.00024251177,0.000029052777,0.00005998252,0.000025843823,0.000114964016,0.00019122669,0.0000054741126],"category_scores_gemma":[0.00038088227,0.00015030731,0.000051573497,0.000078720346,0.00020506425,0.0000053118174,0.00011021091,0.00009459819,4.30626e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057312976,0.000047612684,0.0071749003,0.00020180244,0.000021591368,4.4484e-7,0.000027492622,4.293262e-7,0.9902001,0.00042516715,0.0000036598683,0.0018394775],"study_design_scores_gemma":[0.00039471113,0.00021724805,0.011776838,0.000028875329,0.000011983767,0.000010335319,0.000024540372,0.00006379756,0.9857432,0.00021277729,0.001355397,0.00016027899],"about_ca_topic_score_codex":0.00005917584,"about_ca_topic_score_gemma":0.000050699226,"teacher_disagreement_score":0.004601938,"about_ca_system_score_codex":0.0000102342865,"about_ca_system_score_gemma":0.00004114275,"threshold_uncertainty_score":0.6129354},"labels":[],"label_agreement":null},{"id":"W1996006831","doi":"10.1016/j.febslet.2013.09.028","title":"Targeted expression, purification, and cleavage of fusion proteins from inclusion bodies in <i>Escherichia coli</i>","year":2013,"lang":"en","type":"review","venue":"FEBS Letters","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Cyanogen bromide; Fusion protein; Inclusion bodies; Chemistry; Escherichia coli; Cleavage (geology); Ketosteroid; Biochemistry; Fusion; Formic acid; Isomerase; Combinatorial chemistry; Peptide sequence; Biology; Enzyme","score_opus":0.016949714834301126,"score_gpt":0.26191052798713477,"score_spread":0.24496081315283363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996006831","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.034564875,0.96270317,0.0003082126,0.00033107767,0.000077967095,0.0017917481,0.0001385468,0.00001475768,0.00006966931],"genre_scores_gemma":[0.007033499,0.98824024,0.0024973187,0.00036600514,0.00010384161,0.0005516767,0.0011058288,0.000039019887,0.00006254027],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980276,0.00035448238,0.0006486917,0.0005977435,0.00017830517,0.00019313025],"domain_scores_gemma":[0.9987397,0.000028550581,0.00043723933,0.0006590245,0.000060111037,0.00007536668],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027025538,0.0003065688,0.000653075,0.00008559821,0.00011403787,0.000021245163,0.0003268199,0.0003835122,0.000023787621],"category_scores_gemma":[0.00014676008,0.0002562464,0.00013322681,0.000117499185,0.0001420122,0.000008710214,0.0005367741,0.00022391068,0.000008005878],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032034448,0.00011165697,0.00008264478,0.0022144415,0.000034265944,0.0000012193208,0.00023084582,6.4604257e-7,0.8965451,0.000007168828,0.0034892617,0.0972507],"study_design_scores_gemma":[0.00026145345,0.00004069131,0.0004527722,0.0012116861,0.000039381594,5.630047e-7,0.000017565011,0.0000024316364,0.08537787,0.000029657152,0.91226095,0.00030497918],"about_ca_topic_score_codex":0.00012757236,"about_ca_topic_score_gemma":0.000022702443,"teacher_disagreement_score":0.9087717,"about_ca_system_score_codex":0.000030569787,"about_ca_system_score_gemma":0.00008697973,"threshold_uncertainty_score":0.999989},"labels":[],"label_agreement":null},{"id":"W1996325903","doi":"10.1002/bit.10522","title":"Modeling of scale‐down effects on the hydrodynamics of expanded bed adsorption columns","year":2003,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Polytechnique Montréal; National Research Council Canada; Biotechnology Research Institute","funders":"","keywords":"Dispersion (optics); Chromatography; Adsorption; Scaling; Breakthrough curve; Separation process; Chemistry; Packed bed; Viscosity; Expanded bed adsorption; Mechanics; Filtration (mathematics); Superficial velocity; Simulated moving bed; Fluidized bed; Centrifugation; Materials science; Flow (mathematics); Composite material; Physics; Optics; Elution; Geometry; Mathematics","score_opus":0.005582431878244733,"score_gpt":0.19792372220893045,"score_spread":0.19234129033068573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996325903","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9803007,0.0006162742,0.018599784,0.00018666698,0.000041329233,0.00017704528,0.0000050948374,0.000017893004,0.00005520183],"genre_scores_gemma":[0.99901724,0.00022140761,0.00070574944,0.000014360188,0.0000075015064,0.000014931931,0.0000055994815,0.0000059097338,0.000007305142],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995312,0.000027535238,0.00014153242,0.00015632182,0.00004407712,0.00009933149],"domain_scores_gemma":[0.999644,0.000013893231,0.000039245886,0.0002603086,0.000025716656,0.000016872385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018076863,0.0000804565,0.000105801024,0.00004447327,0.000028165994,0.0000023262671,0.00008536534,0.00024487166,0.0000014774141],"category_scores_gemma":[0.00011748749,0.000063384054,0.00003510283,0.00008688387,0.00009351699,0.0000015464135,0.000025272195,0.0000875845,2.9632378e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018652194,0.000025083942,0.0003348856,0.00004128024,0.000020073041,8.5006846e-8,0.000011455637,0.001025997,0.9928925,0.0046694046,0.0000010972049,0.00095947646],"study_design_scores_gemma":[0.00018056502,0.00015855902,0.00026137667,0.000019080022,0.0000087399985,0.0000035166704,0.000035160912,0.025884816,0.97309196,0.00014752561,0.00013859986,0.00007012375],"about_ca_topic_score_codex":0.0000036083952,"about_ca_topic_score_gemma":0.000005904137,"teacher_disagreement_score":0.02485882,"about_ca_system_score_codex":0.000005191105,"about_ca_system_score_gemma":0.000011753475,"threshold_uncertainty_score":0.25847268},"labels":[],"label_agreement":null},{"id":"W1996554979","doi":"10.1016/j.colsurfb.2015.03.013","title":"Low molecular weight silicones particularly facilitate human serum albumin denaturation","year":2015,"lang":"en","type":"article","venue":"Colloids and Surfaces B Biointerfaces","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Denaturation (fissile materials); Silicone; Polydimethylsiloxane; Silicone oil; Chemistry; Bovine serum albumin; Chemical engineering; Human serum albumin; Pulmonary surfactant; Chromatography; Albumin; Turbidity; Hydrophobic effect; Protein aggregation; Polymer chemistry; Organic chemistry; Biochemistry; Nuclear chemistry","score_opus":0.021624948239431105,"score_gpt":0.2551368353016897,"score_spread":0.23351188706225856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996554979","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900443,0.0069359164,0.0009847775,0.0006381253,0.00014660996,0.00036278157,0.000051358955,0.00003769034,0.00079845806],"genre_scores_gemma":[0.9970798,0.0001251559,0.00043282594,0.00011439664,0.00003281158,0.00003537727,0.000071925126,0.000016660004,0.0020910646],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985445,0.00016033908,0.00030954197,0.0005200285,0.00018932633,0.00027627381],"domain_scores_gemma":[0.99908936,0.000010442478,0.00009083584,0.00039435553,0.00019564615,0.00021933904],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041467987,0.00023234906,0.00021038378,0.00003988198,0.00014049656,0.00012982213,0.00019072999,0.00016973267,0.000016453612],"category_scores_gemma":[0.000111814144,0.00020251551,0.000073803414,0.00010823765,0.00022666989,0.000023646217,0.00012165055,0.00009569544,0.00001809764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008565883,0.00008879346,0.010188019,0.00003776346,0.000055995293,0.000003270774,0.00029623465,0.000081711405,0.9868573,0.00018924582,0.0008277527,0.0012882852],"study_design_scores_gemma":[0.0008534296,0.00046111114,0.0056894524,0.000019849478,0.000020062833,0.0000094751895,0.0005483544,0.0005064561,0.95781267,0.00041955098,0.033296485,0.00036312517],"about_ca_topic_score_codex":0.000046133595,"about_ca_topic_score_gemma":0.00010533383,"teacher_disagreement_score":0.032468732,"about_ca_system_score_codex":0.00001972569,"about_ca_system_score_gemma":0.00007614618,"threshold_uncertainty_score":0.8258343},"labels":[],"label_agreement":null},{"id":"W1998741529","doi":"10.1016/j.dental.2014.05.031","title":"Biodegradation of composite resin with ester linkages: Identifying human salivary enzyme activity with a potential role in the esterolytic process","year":2014,"lang":"en","type":"article","venue":"Dental Materials","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Esterase; Biochemistry; Chromatography; Saliva; Albumin; Isoelectric point; Chemistry; Lysozyme; Enzyme","score_opus":0.009143842564666493,"score_gpt":0.2576932409896059,"score_spread":0.2485493984249394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998741529","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981791,0.000030407327,0.001280433,0.000050468378,0.000025673464,0.00034115007,0.000018899418,0.0000070236306,0.000066864784],"genre_scores_gemma":[0.99956524,0.0000021170795,0.00013609846,0.000050442715,0.00004417073,0.00004746951,0.00012877682,0.000010529662,0.000015180267],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990929,0.0002328014,0.00018095669,0.0002254401,0.0001534752,0.000114469156],"domain_scores_gemma":[0.99951464,0.000006489821,0.00014187793,0.00027909767,0.000037456844,0.0000204111],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036470476,0.000106232575,0.00013585751,0.000031089006,0.000060701106,0.000068066016,0.00017381522,0.00006464262,0.000009505801],"category_scores_gemma":[0.000009561186,0.0000696034,0.000018784745,0.000059242124,0.00008838222,0.000015465559,0.000032034855,0.000041386116,0.0000018892938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026345224,0.00011307517,0.009289064,0.00007729622,0.000011450328,0.0000012027023,0.00015767271,0.000010854263,0.98992574,0.000022176693,0.0000014116124,0.00012658471],"study_design_scores_gemma":[0.0005034531,0.0002117738,0.1606189,0.000037177797,0.000013257594,0.000017294016,0.000121866855,0.000011556425,0.8383044,0.00006263446,0.000013743424,0.00008395333],"about_ca_topic_score_codex":0.00009857829,"about_ca_topic_score_gemma":0.000117841046,"teacher_disagreement_score":0.15162137,"about_ca_system_score_codex":0.000008059838,"about_ca_system_score_gemma":0.000015632946,"threshold_uncertainty_score":0.2838344},"labels":[],"label_agreement":null},{"id":"W1998868325","doi":"10.1016/j.chroma.2013.02.051","title":"Design of batch chromatography for separation of binary mixtures under reduced purity requirements","year":2013,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Simulated moving bed; Chromatography; Binary number; Adsorption; Volume (thermodynamics); Separation (statistics); Work (physics); Column (typography); Column chromatography; Position (finance); Process engineering; Thermodynamics; Mathematics; Organic chemistry; Statistics","score_opus":0.02531666254778957,"score_gpt":0.3006522393000816,"score_spread":0.27533557675229203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998868325","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96508515,0.0023173094,0.031602744,0.00019404676,0.000104285755,0.0006126611,0.000012125541,0.0000045447277,0.00006712602],"genre_scores_gemma":[0.9886964,0.00026157612,0.010871008,0.000043889395,0.000053883916,0.000037965234,0.000016494922,0.00001212362,0.000006688189],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985727,0.00014701545,0.00072596554,0.00016349691,0.00023923346,0.00015159331],"domain_scores_gemma":[0.9981233,0.00003283591,0.0008259843,0.00030007082,0.00063671474,0.00008113048],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005445521,0.00013603964,0.00029435626,0.00020607357,0.00004867429,0.000015216392,0.00024059915,0.00014825987,0.000029675122],"category_scores_gemma":[0.00006834142,0.0001159601,0.00037428728,0.00025576132,0.00016214137,0.000025820033,0.000023886272,0.00007468944,4.000251e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021973056,0.00031167944,0.0022068184,0.00011224701,0.00022536672,2.426525e-7,0.000076011944,0.0000705338,0.9943536,0.00007542728,0.002019911,0.0003284277],"study_design_scores_gemma":[0.0011284018,0.0012654779,0.038564745,0.00006176432,0.00005954114,0.000017953858,0.00011158742,0.000099719415,0.9547879,0.0032868525,0.00047613532,0.00013991591],"about_ca_topic_score_codex":0.000011663024,"about_ca_topic_score_gemma":8.383918e-7,"teacher_disagreement_score":0.039565697,"about_ca_system_score_codex":0.000007718517,"about_ca_system_score_gemma":0.000116501746,"threshold_uncertainty_score":0.47287157},"labels":[],"label_agreement":null},{"id":"W1999495784","doi":"10.1080/19443994.2013.810324","title":"Adsorption of antiviral drug, acyclovir from aqueous solution on powdered activated charcoal: kinetics, equilibrium, and thermodynamic studies","year":2013,"lang":"en","type":"article","venue":"Desalination and Water Treatment","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"University of Saskatchewan","keywords":"Adsorption; Freundlich equation; Chemistry; Endothermic process; Langmuir; Aqueous solution; Activated charcoal; Physisorption; Kinetics; Chromatography; Nuclear chemistry; Organic chemistry","score_opus":0.016943650357217007,"score_gpt":0.25974612181591483,"score_spread":0.24280247145869782,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999495784","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977684,0.00074772525,0.000102857615,0.0008241729,0.000039344915,0.00040050255,0.00003136742,0.000014460568,0.00007114396],"genre_scores_gemma":[0.99855816,0.0005178707,0.00012067117,0.00004967538,0.000025892718,0.00006551534,0.00042332042,0.000009405905,0.0002295127],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932826,0.000086020744,0.00015843367,0.00025110756,0.00006847965,0.000107692955],"domain_scores_gemma":[0.99965686,0.000011598923,0.00005793519,0.00015694914,0.0000842693,0.000032379303],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000054058353,0.00012557549,0.0001274976,0.000034940073,0.0000300215,0.000017008088,0.00003157275,0.00006521443,0.000009601028],"category_scores_gemma":[0.000013824491,0.000084863634,0.000029692603,0.000019522584,0.00008829527,0.000013129428,0.00003110733,0.000022815158,0.0000054203097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000778133,0.00017701383,0.00063009775,0.00001040413,0.0000761455,1.5945142e-7,0.00038839362,0.000001760047,0.9791988,0.00004155561,0.000013329403,0.019384531],"study_design_scores_gemma":[0.00084281934,0.00038468625,0.02209618,0.000010718964,0.000019709592,7.3929147e-7,0.00011316074,0.0005998375,0.97496194,0.00055335346,0.00031862155,0.00009824528],"about_ca_topic_score_codex":0.00014600386,"about_ca_topic_score_gemma":0.00001844522,"teacher_disagreement_score":0.021466082,"about_ca_system_score_codex":0.00003298032,"about_ca_system_score_gemma":0.000006146111,"threshold_uncertainty_score":0.34606385},"labels":[],"label_agreement":null},{"id":"W1999534182","doi":"10.1002/1520-6017(200012)89:12<1589::aid-jps10>3.0.co;2-6","title":"The Effect of Serum Albumin on the Aggregation State and Toxicity of Amphotericin B","year":2000,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Amphotericin B; Toxicity; Chemistry; Albumin; Serum albumin; Pharmacology; Biochemistry; Medicine; Microbiology; Antifungal; Biology; Organic chemistry","score_opus":0.017646133415078098,"score_gpt":0.32732225351205096,"score_spread":0.3096761200969729,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999534182","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970334,0.000804803,0.000040356535,0.0015923865,0.00003323964,0.00008744648,0.00000400674,3.9312746e-7,0.00040394615],"genre_scores_gemma":[0.99916184,0.0006506497,0.000027709426,0.00009335572,0.000020074911,8.930962e-7,7.229986e-8,0.0000010068425,0.000044382636],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923176,0.00022836665,0.00020355023,0.000068565125,0.0001879386,0.000079851015],"domain_scores_gemma":[0.99954873,0.0001639072,0.0001342082,0.00007146722,0.00004189916,0.000039781455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018655293,0.000043818738,0.000075474934,0.000010291028,0.00009403258,0.00001370433,0.00017711382,0.000019433153,0.000054870725],"category_scores_gemma":[0.00020874839,0.000018973851,0.000042665615,0.00008338959,0.0005328115,0.0000049058112,0.00001549341,0.00006535079,5.6216254e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004000353,0.000037924896,0.005792682,0.0000145590875,0.000018558694,3.3680644e-7,0.00005470095,0.0000718046,0.73851097,0.000092435934,0.00006513672,0.25494087],"study_design_scores_gemma":[0.00019797913,0.00081503077,0.008704607,0.000010760065,0.0000070644714,0.0000058885735,0.000015502148,0.0002941688,0.985504,0.0001696433,0.0042519765,0.00002343407],"about_ca_topic_score_codex":0.0000017877747,"about_ca_topic_score_gemma":0.0000016585221,"teacher_disagreement_score":0.25491744,"about_ca_system_score_codex":0.0000040677605,"about_ca_system_score_gemma":0.000027968936,"threshold_uncertainty_score":0.19631661},"labels":[],"label_agreement":null},{"id":"W2000393832","doi":"10.1002/bit.24771","title":"Zonal rate model for axial and radial flow membrane chromatography. Part I: Knowledge transfer across operating conditions and scales","year":2012,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Bayer HealthCare","keywords":"Capsule; Volumetric flow rate; Membrane; Flow (mathematics); Calibration; Chemistry; Scale (ratio); Homogeneous; Mechanics; Chromatography; Biological system; Bovine serum albumin; Analytical Chemistry (journal); Materials science; Thermodynamics; Physics; Mathematics; Geology; Statistics; Biochemistry","score_opus":0.014141129671668008,"score_gpt":0.2568937251671926,"score_spread":0.2427525954955246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000393832","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9376368,0.0058118533,0.05569893,0.0003030167,0.000078870136,0.00023629752,0.00018180771,0.000044925826,0.000007517939],"genre_scores_gemma":[0.99622256,0.00068414013,0.0027890294,0.000028581964,0.000102389065,0.00007679015,0.000068254885,0.000010796583,0.00001746063],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99935263,0.000014049073,0.00013193833,0.0002316925,0.0000205284,0.0002491299],"domain_scores_gemma":[0.9997613,0.000013637853,0.000011833395,0.000114435454,0.00002071206,0.000078087825],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020859283,0.00012851505,0.00012395548,0.00003728119,0.00019163241,0.000019273253,0.000049394865,0.0003200509,0.0000015709628],"category_scores_gemma":[0.00003244288,0.00012141157,0.000032395412,0.000049184062,0.0002704074,0.0000111374175,0.000042934684,0.00008636088,2.6275018e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028038268,0.00004007227,0.0008356425,0.00008381562,0.00004696915,1.3627319e-7,0.00013226998,0.000072065486,0.9919546,0.0023538086,0.000015672793,0.0044369106],"study_design_scores_gemma":[0.001572306,0.00018085504,0.005312417,0.000025931919,0.00003936617,0.00006546671,0.00013809022,0.117384605,0.8647857,0.00009435109,0.009940152,0.00046077522],"about_ca_topic_score_codex":0.000001012624,"about_ca_topic_score_gemma":0.000013593999,"teacher_disagreement_score":0.12716891,"about_ca_system_score_codex":0.000003229074,"about_ca_system_score_gemma":0.00001089536,"threshold_uncertainty_score":0.49510202},"labels":[],"label_agreement":null},{"id":"W2000816243","doi":"10.1016/j.chroma.2014.07.014","title":"Multi-variable operational characteristic studies of on-column oxidative protein refolding at high loading concentrations","year":2014,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland; Western University","funders":"","keywords":"Chemistry; Oxidative phosphorylation; Chromatography; Column (typography); Variable (mathematics); Biochemistry","score_opus":0.020735382636181153,"score_gpt":0.2817375034469613,"score_spread":0.26100212081078017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000816243","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99217606,0.0006158376,0.0065541,0.00015714583,0.00010585703,0.00022497088,0.000027621538,0.000004031977,0.00013436741],"genre_scores_gemma":[0.9892328,0.00008043926,0.010384712,0.00008575155,0.000108042426,0.000020740554,0.000019733465,0.000008002352,0.0000597983],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989128,0.00015015992,0.00048023387,0.00015288443,0.0001838017,0.00012012278],"domain_scores_gemma":[0.9987612,0.000038011218,0.00048489237,0.00018552915,0.00046527953,0.00006512097],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005116526,0.00010841731,0.00024024147,0.00007885202,0.0001320609,0.000017660243,0.00013826504,0.0000694334,0.000030137524],"category_scores_gemma":[0.0005029736,0.000091519694,0.000120043405,0.00013314962,0.00014317299,0.00001352952,0.000034356755,0.00008799357,0.0000013781992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010297303,0.00015182482,0.0034426516,0.000042991,0.00017807822,6.494392e-7,0.00009975378,0.000036273435,0.993279,0.0024296744,0.0001281891,0.00010797338],"study_design_scores_gemma":[0.0013914431,0.00077748514,0.02340954,0.00020408376,0.000040377334,0.000023423236,0.00018082286,0.00016737163,0.96700466,0.0003245117,0.006298796,0.00017751554],"about_ca_topic_score_codex":0.000003988206,"about_ca_topic_score_gemma":0.0000038555613,"teacher_disagreement_score":0.026274337,"about_ca_system_score_codex":0.000029603678,"about_ca_system_score_gemma":0.0000772007,"threshold_uncertainty_score":0.3732065},"labels":[],"label_agreement":null},{"id":"W2003066318","doi":"10.1208/s12248-010-9205-1","title":"Micro-Flow Imaging: Flow Microscopy Applied to Sub-visible Particulate Analysis in Protein Formulations","year":2010,"lang":"en","type":"article","venue":"The AAPS Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":181,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Optech (Canada)","funders":"Genentech; Eli Lilly and Company","keywords":"Particulates; Repeatability; Particle (ecology); Materials science; Flow (mathematics); Nanotechnology; Microscopy; Sensitivity (control systems); Measure (data warehouse); Biological system; Optics; Chemistry; Computer science; Chromatography; Mechanics; Data mining; Physics; Engineering","score_opus":0.00686604465032589,"score_gpt":0.26131075404021303,"score_spread":0.25444470938988717,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003066318","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97712815,0.00013874231,0.020271532,0.0017912255,0.000069386704,0.00038548186,0.000012839132,0.00000793076,0.00019472958],"genre_scores_gemma":[0.9868495,0.000011770336,0.012557902,0.0002658771,0.00012388342,0.000048838556,0.000027745624,0.000011799253,0.00010270738],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898326,0.000072616174,0.0003124242,0.00022838797,0.00012651861,0.00027681605],"domain_scores_gemma":[0.99914265,0.000008430286,0.00009926551,0.0005111224,0.00010714134,0.00013140113],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00078210473,0.00012298339,0.000142957,0.00010865127,0.00021456725,0.000103813036,0.00030309753,0.00006844489,0.000070379734],"category_scores_gemma":[0.00009421447,0.0000907373,0.00013019887,0.00039067736,0.00006508609,0.0000069892867,0.00006993443,0.00030882494,0.000026177075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007557928,0.000059325783,0.008380149,0.0000022549561,0.000055068904,0.0000011392489,0.0001138535,0.0012714808,0.9864584,0.00004844978,0.00015435102,0.0033799063],"study_design_scores_gemma":[0.00053372636,0.00002983702,0.039547343,0.000004596924,0.000065334025,0.000024722423,0.000042753047,0.0028359147,0.9456315,0.001052833,0.010040304,0.00019110297],"about_ca_topic_score_codex":0.000010549487,"about_ca_topic_score_gemma":0.00018061274,"teacher_disagreement_score":0.04082691,"about_ca_system_score_codex":0.000017705415,"about_ca_system_score_gemma":0.000079332494,"threshold_uncertainty_score":0.370016},"labels":[],"label_agreement":null},{"id":"W2006599164","doi":"10.1016/s1046-5928(02)00017-7","title":"An Arg/Lys→Gln mutant of recombinant murine myelin basic protein as a mimic of the deiminated form implicated in multiple sclerosis","year":2002,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Guelph","funders":"","keywords":"Citrullination; Myelin basic protein; Chemistry; Mutant; Biochemistry; Cathepsin D; Mutant protein; Arginine; Molecular biology; Citrulline; Biology; Enzyme; Myelin; Amino acid; Gene","score_opus":0.028502511897261305,"score_gpt":0.2397491917154916,"score_spread":0.2112466798182303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006599164","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99608105,0.0009011067,0.0003319465,0.00040592058,0.000025867863,0.0021254725,0.000023622286,0.00001604888,0.00008893771],"genre_scores_gemma":[0.9980733,0.00020076841,0.0008574659,0.000022738734,0.000013501947,0.0006165003,0.000057981877,0.000018372108,0.00013937004],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982986,0.00027197588,0.0005756993,0.00046608155,0.00018799784,0.00019965778],"domain_scores_gemma":[0.99850804,0.000012652766,0.000388829,0.0008361536,0.00017058002,0.00008375494],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046026515,0.00017572042,0.00020957837,0.00008035518,0.000103113205,0.000014642285,0.00032222603,0.0002077376,0.000058143767],"category_scores_gemma":[0.00030686805,0.0001318437,0.00007185622,0.00026392998,0.0001564627,0.000020164258,0.00007497057,0.00014003796,0.0000030353028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019317064,0.0005216968,0.001615078,0.00008825903,0.0000057431344,1.3485291e-7,0.00022658211,0.000004190877,0.97489303,0.00013650094,0.000012103388,0.0223035],"study_design_scores_gemma":[0.001054316,0.00022650864,0.025358213,0.00018402764,0.0000062546933,0.0000025207546,0.0000959315,0.001310617,0.97021115,0.000561777,0.00083488855,0.00015379486],"about_ca_topic_score_codex":0.00010467091,"about_ca_topic_score_gemma":0.000028870323,"teacher_disagreement_score":0.023743136,"about_ca_system_score_codex":0.00001994103,"about_ca_system_score_gemma":0.000036736994,"threshold_uncertainty_score":0.537643},"labels":[],"label_agreement":null},{"id":"W2006943702","doi":"10.1016/j.clinbiochem.2013.07.010","title":"Challenges in identifying some IgM monoclonal proteins by capillary serum protein electrophoresis","year":2013,"lang":"en","type":"letter","venue":"Clinical Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; University of Toronto","funders":"","keywords":"Capillary electrophoresis; Monoclonal; Monoclonal antibody; Chemistry; Chromatography; Biology; Immunology; Antibody","score_opus":0.06100368415355485,"score_gpt":0.3212951812584569,"score_spread":0.26029149710490207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006943702","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4420997,0.09551974,0.000046549852,0.4564717,0.00042556642,0.0032644076,0.0005322125,0.00012179979,0.0015183088],"genre_scores_gemma":[0.58560413,0.054523338,0.0027695633,0.27217764,0.022373501,0.0071791,0.01379952,0.00074649754,0.04082669],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99469763,0.00043532552,0.0013822329,0.002131789,0.00047274693,0.00088026124],"domain_scores_gemma":[0.9971479,0.00006944143,0.00053105794,0.0018408609,0.00018129828,0.00022940383],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00093543984,0.0006839577,0.0007704812,0.00006398201,0.000096839554,0.0000890027,0.0010611259,0.0037638976,0.0001429898],"category_scores_gemma":[0.0009234031,0.0006961457,0.0004989277,0.00011586194,0.00042005852,0.000011973879,0.00037475978,0.002638727,0.00010703142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008563153,0.00033696083,0.00036118715,0.0008901868,0.00015453961,0.000054210712,0.000008048268,1.2009268e-7,0.5935871,0.000008470958,0.39686364,0.0076498953],"study_design_scores_gemma":[0.00065205095,0.00019271862,0.0004204871,0.00014945534,0.000024371215,0.000013904567,0.000017961274,0.0000050979233,0.57799953,0.0006612976,0.41903847,0.0008246314],"about_ca_topic_score_codex":0.00003001421,"about_ca_topic_score_gemma":0.0000079145275,"teacher_disagreement_score":0.18429409,"about_ca_system_score_codex":0.00010866459,"about_ca_system_score_gemma":0.0004538139,"threshold_uncertainty_score":0.9996622},"labels":[],"label_agreement":null},{"id":"W2007810266","doi":"10.1016/j.memsci.2005.03.024","title":"Fractionation of human plasma proteins by hydrophobic interaction membrane chromatography","year":2005,"lang":"en","type":"article","venue":"Journal of Membrane Science","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"McMaster University; Ontario Innovation Trust","keywords":"Membrane; Chromatography; Chemistry; Microporous material; Chaotropic agent; Fractionation; Affinity chromatography; Ammonium; Biochemistry; Organic chemistry","score_opus":0.009092945796285277,"score_gpt":0.2774369439208501,"score_spread":0.26834399812456483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007810266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99736327,0.00021635783,0.0005864965,0.0005614308,0.0001358241,0.00014245091,0.0000050084427,0.0000041583157,0.0009850308],"genre_scores_gemma":[0.9985266,0.00010287952,0.0011072117,0.00005734961,0.000103841914,0.000004413461,0.0000058048954,0.000005434547,0.0000864913],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987378,0.000052910484,0.00044416072,0.00018388458,0.00045086493,0.00013037103],"domain_scores_gemma":[0.99874675,0.000010876097,0.00054529594,0.00021213353,0.00039416977,0.00009075527],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009548681,0.000086085456,0.00013358484,0.000180986,0.0001319194,0.00002675759,0.00032254454,0.00006363489,0.00006688459],"category_scores_gemma":[0.00015935604,0.00007512765,0.000099769786,0.0003202554,0.00027963417,0.00006416133,0.00002858491,0.00013330448,0.0000030122123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055510074,0.00016172985,0.00016519154,0.000014440081,0.000010512954,2.553039e-7,0.000045999037,0.00012565685,0.9968788,0.00005320206,0.000121342666,0.0023673587],"study_design_scores_gemma":[0.00042265572,0.0002850605,0.0014026664,0.000018506093,0.0000071556515,0.000051351108,0.000054748885,0.00023820007,0.98310757,0.000025766829,0.014311237,0.0000751032],"about_ca_topic_score_codex":0.00000917203,"about_ca_topic_score_gemma":0.0000066497505,"teacher_disagreement_score":0.014189894,"about_ca_system_score_codex":0.00003937492,"about_ca_system_score_gemma":0.00014976053,"threshold_uncertainty_score":0.30636168},"labels":[],"label_agreement":null},{"id":"W2008290735","doi":"10.1365/s10337-007-0437-x","title":"A Series of Collaborations between Various Pharmaceutical Companies and Regulatory Authorities Concerning the Analysis of Biomolecules Using Capillary Electrophoresis: Additional Instruments/Buffer","year":2007,"lang":"en","type":"article","venue":"Chromatographia","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada; Women's Health Research Institute","funders":"","keywords":"Chemistry; Capillary electrophoresis; Immunoglobulin light chain; Chain (unit); Chromatography; Sample (material); Heavy chain; Value (mathematics); Biomolecule; Bovine serum albumin; Biopharmaceutical; Buffer (optical fiber); Value chain; Business; Antibody; Biochemistry; Statistics; Biotechnology; Marketing; Computer science; Immunology; Mathematics","score_opus":0.028818782983729373,"score_gpt":0.2858901997143849,"score_spread":0.25707141673065553,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008290735","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952605,0.0028677236,0.00093329436,0.000051580402,0.00001791347,0.0001461399,0.0006493241,0.000008496378,0.000065026354],"genre_scores_gemma":[0.998448,0.00016288582,0.0009311087,0.000021660064,0.000028343284,0.000009686679,0.00038639572,0.0000071638283,0.0000047569483],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991035,0.00009010386,0.0003216669,0.00018582382,0.00015758454,0.00014134785],"domain_scores_gemma":[0.9993525,0.000045743807,0.00015484523,0.00021732796,0.0001774821,0.000052070904],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027004443,0.000105707164,0.00021218784,0.00016915122,0.00015524344,0.000014867151,0.00010582823,0.000088406756,0.00005300907],"category_scores_gemma":[0.00004923135,0.000089995796,0.000099232595,0.00067801087,0.00081359444,0.000007670078,0.000048238355,0.00005082692,7.9852676e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012238008,0.000073443116,0.095798776,0.00007051205,0.0019240222,0.0000010948784,0.00033350918,0.00002005526,0.8954127,0.0054842453,0.00019907707,0.0005602281],"study_design_scores_gemma":[0.00034764872,0.00012293643,0.47810772,0.000022385682,0.0007163951,0.000011430613,0.0010528337,0.00022940947,0.51464576,0.00031817573,0.004234973,0.00019032667],"about_ca_topic_score_codex":0.000026487669,"about_ca_topic_score_gemma":0.00007628514,"teacher_disagreement_score":0.38230893,"about_ca_system_score_codex":0.000009626562,"about_ca_system_score_gemma":0.00009006868,"threshold_uncertainty_score":0.3669922},"labels":[],"label_agreement":null},{"id":"W2009810598","doi":"10.1016/j.chroma.2014.10.042","title":"Oxidative protein refolding on size exclusion chromatography at high loading concentrations: Fundamental studies and mathematical modeling","year":2014,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland; Western University","funders":"","keywords":"Chemistry; Lysozyme; Size-exclusion chromatography; Chromatography; Yield (engineering); Kinetics; Protein aggregation; Urea; Oxidative phosphorylation; Lysine; Biochemistry; Amino acid; Enzyme; Thermodynamics","score_opus":0.018570885435348686,"score_gpt":0.27738547165385063,"score_spread":0.25881458621850195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009810598","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99219406,0.002877682,0.004056175,0.0002932782,0.00004390881,0.00029275345,0.000004141873,0.00001223104,0.00022578082],"genre_scores_gemma":[0.9931789,0.00034854736,0.006197132,0.000121591576,0.00010644017,0.000015582054,0.000003847134,0.000012842093,0.000015100743],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99857676,0.00017283986,0.00053075724,0.00024846627,0.00028077242,0.00019039126],"domain_scores_gemma":[0.99903256,0.00006553614,0.0003661089,0.00022327734,0.00018639342,0.00012613104],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006665988,0.00018758528,0.00031465388,0.000115699884,0.00023729716,0.000043098276,0.00013781575,0.00010280018,0.000022015523],"category_scores_gemma":[0.00034823918,0.0001481215,0.00019120179,0.00015426645,0.00016808975,0.000020998907,0.00007273149,0.00013061437,0.000002173768],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003437546,0.00018848763,0.0007076503,0.00013737603,0.00025487397,0.0000033254753,0.0003376442,0.0000494252,0.9926725,0.003714876,0.00007860886,0.0015114668],"study_design_scores_gemma":[0.004388903,0.004519772,0.0040718904,0.0015856543,0.00016823334,0.00027157838,0.0015751903,0.0025564176,0.9393857,0.038118213,0.0025375434,0.00082088663],"about_ca_topic_score_codex":9.588188e-7,"about_ca_topic_score_gemma":0.0000013901168,"teacher_disagreement_score":0.053286795,"about_ca_system_score_codex":0.000034390483,"about_ca_system_score_gemma":0.000025626372,"threshold_uncertainty_score":0.60402197},"labels":[],"label_agreement":null},{"id":"W2011518324","doi":"10.1007/s10928-015-9406-4","title":"A PBPK workflow for first-in-human dose selection of a subcutaneously administered pegylated peptide","year":2015,"lang":"en","type":"article","venue":"Journal of Pharmacokinetics and Pharmacodynamics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Physiologically based pharmacokinetic modelling; Pharmacokinetics; Dosing; Pharmacology; In silico; Workflow; In vivo; PEGylation; Medicine; Computational biology; Chemistry; Computer science; Biology; Biotechnology","score_opus":0.026206120513424767,"score_gpt":0.32442810617979173,"score_spread":0.298221985666367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011518324","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994889,0.0011615442,0.0029360233,0.0002692912,0.00021913822,0.0003561098,0.000045736113,0.0000042920046,0.00011881886],"genre_scores_gemma":[0.99659276,0.00072983897,0.0022277331,0.00008759893,0.00018942916,0.000010554118,0.000025634356,0.000020936459,0.00011551408],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998748,0.00007722324,0.00063000125,0.00018229256,0.00017347057,0.00018899694],"domain_scores_gemma":[0.9987223,0.000030746225,0.00043764003,0.00010518713,0.0005035932,0.00020051558],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006324589,0.00015603889,0.00025356177,0.0001159424,0.00004443421,0.000020335516,0.00017345486,0.00009734129,0.000014096031],"category_scores_gemma":[0.00009320897,0.00015053005,0.00011499735,0.00014537004,0.00006931302,0.00001030501,0.000039781873,0.00017121516,1.887759e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027209788,0.00049807644,0.006316636,0.0001787752,0.0001478413,0.000014383626,0.00028041124,0.0025058847,0.9806089,0.000085650216,0.00082187704,0.0058206324],"study_design_scores_gemma":[0.037089627,0.008595326,0.007677277,0.00025455828,0.00076014065,0.0012404848,0.0003962217,0.2105699,0.5648155,0.0032057543,0.16397212,0.0014230728],"about_ca_topic_score_codex":0.0000056027334,"about_ca_topic_score_gemma":0.00003004707,"teacher_disagreement_score":0.41579336,"about_ca_system_score_codex":0.000038924478,"about_ca_system_score_gemma":0.00013616284,"threshold_uncertainty_score":0.61384374},"labels":[],"label_agreement":null},{"id":"W2015765945","doi":"10.1021/ed200379f","title":"Web-Based Applet Is a Learning Tool that Simulates Ion-Exchange Chromatography Purification of Overexpressed Proteins from <i>Escherichia coli</i> Cell Lysate","year":2012,"lang":"en","type":"article","venue":"Journal of Chemical Education","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Java applet; Lysis; Chromatography; Chemistry; Absorbance; Escherichia coli; Ion chromatography; Ion exchange; Visualization; Polyacrylamide gel electrophoresis; Gel electrophoresis; Biochemistry; Computer science; Java; Ion; Data mining; Programming language; Organic chemistry","score_opus":0.00959378251808118,"score_gpt":0.24184561649399897,"score_spread":0.23225183397591778,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015765945","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99664277,0.0016869083,0.0006252959,0.00039563156,0.0001411437,0.00031363792,0.000022143186,0.000008245878,0.00016423741],"genre_scores_gemma":[0.99514616,0.00009334544,0.003905741,0.00026841986,0.00035841163,0.000044503766,0.00012898531,0.000018408693,0.000036030164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99883235,0.00010857335,0.00044904664,0.00017526884,0.0002578892,0.0001768537],"domain_scores_gemma":[0.99851406,0.000036868405,0.0007242095,0.00028696988,0.00030791157,0.00012999265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003664573,0.00014653493,0.00020841436,0.0000641454,0.000038677896,0.000021589562,0.000201546,0.00019128052,0.000101664664],"category_scores_gemma":[0.00017206845,0.00013636166,0.00018139955,0.00014930977,0.00006796349,0.000028298822,0.000023961024,0.00019834185,0.0000033182343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015081603,0.0006482942,0.007399866,0.000088382585,0.000028246921,4.069077e-8,0.00024586354,0.000008498486,0.98948866,0.0000037928469,0.00089431513,0.0010432089],"study_design_scores_gemma":[0.00064401963,0.000068357505,0.004503299,0.00004081891,0.000038511822,0.0000010297291,0.000088652334,0.00011484879,0.9594761,0.000061596766,0.03482329,0.00013945067],"about_ca_topic_score_codex":0.000011743962,"about_ca_topic_score_gemma":2.664472e-7,"teacher_disagreement_score":0.033928975,"about_ca_system_score_codex":0.00003227341,"about_ca_system_score_gemma":0.0002928596,"threshold_uncertainty_score":0.5560667},"labels":[],"label_agreement":null},{"id":"W2015773945","doi":"10.1016/j.microc.2011.06.009","title":"Adsorption of phenolic compounds onto trimethylstearylammonium surfactant-immobilized cation-exchange membranes","year":2011,"lang":"en","type":"article","venue":"Microchemical Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Natrix Separations (Canada)","funders":"Ministry of Education; National Science Council; Aba Teachers University; National Science Foundation","keywords":"Adsorption; Pulmonary surfactant; Membrane; Chemistry; Ion exchange; Chemical engineering; Chromatography; Inorganic chemistry; Organic chemistry; Ion; Biochemistry","score_opus":0.025644763915887596,"score_gpt":0.247973218875877,"score_spread":0.2223284549599894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015773945","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99201006,0.005412253,0.0011005418,0.00007854026,0.00010750211,0.0001700688,0.000015229142,0.00001110986,0.0010946738],"genre_scores_gemma":[0.99666995,0.0006971455,0.0021756238,0.00007372715,0.00013218037,0.000010187311,0.000061212886,0.000015944363,0.0001640159],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99881005,0.00011709904,0.00045220138,0.00024346958,0.00015468376,0.0002224962],"domain_scores_gemma":[0.99903333,0.000014214051,0.00024165663,0.00031335207,0.00026069625,0.00013674273],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041838302,0.00014935315,0.00021363137,0.000049735463,0.000062634324,0.000018615057,0.00028378327,0.00025209144,0.00021267563],"category_scores_gemma":[0.0000952316,0.000136201,0.00016256729,0.000093794304,0.00013995211,0.000008942595,0.000055770193,0.00025345484,0.000009710744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034813548,0.000234333,0.0025225987,0.00005049798,0.000043871267,4.76953e-7,0.00030493923,2.8611538e-7,0.9952649,0.000011185497,0.0002944979,0.0009242795],"study_design_scores_gemma":[0.00082685705,0.00011884115,0.0027112234,0.000012542778,0.000022046996,0.0000736009,0.00011440979,0.000006365342,0.9838297,0.000198381,0.011936091,0.00014993972],"about_ca_topic_score_codex":0.00003979872,"about_ca_topic_score_gemma":0.000008396129,"teacher_disagreement_score":0.011641593,"about_ca_system_score_codex":0.000033164546,"about_ca_system_score_gemma":0.000109458386,"threshold_uncertainty_score":0.5554115},"labels":[],"label_agreement":null},{"id":"W2016826833","doi":"10.1016/j.memsci.2008.02.056","title":"Fractionation of monoclonal antibody aggregates using membrane chromatography","year":2008,"lang":"en","type":"article","venue":"Journal of Membrane Science","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Pentamer; Trimer; Dimer; Chemistry; Tetramer; Monomer; Monoclonal antibody; Size-exclusion chromatography; Chromatography; Membrane; Fractionation; Antibody; Organic chemistry; Biochemistry; Polymer","score_opus":0.021857465895528085,"score_gpt":0.3030067309339279,"score_spread":0.2811492650383998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016826833","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958606,0.00096585834,0.0025461055,0.00013838492,0.00016305414,0.00006435271,0.0000037529244,0.0000023966556,0.00025554624],"genre_scores_gemma":[0.9940099,0.000554884,0.00530382,0.000039069797,0.00007128173,4.853731e-7,0.0000027827687,0.00000401971,0.000013718714],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988588,0.000041829226,0.00036136623,0.0001526117,0.00046013933,0.00012522888],"domain_scores_gemma":[0.9986816,0.0000145535205,0.00046166385,0.00018060926,0.0005770653,0.00008447807],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008136485,0.00007311496,0.00013741011,0.00017961476,0.00015401519,0.000011399293,0.00028913433,0.000051056842,0.00002451039],"category_scores_gemma":[0.00029107183,0.00006209187,0.00010672967,0.00041607293,0.0005458549,0.00003810882,0.000030495292,0.00008331871,7.0843214e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004753316,0.000076866265,0.0045462637,0.000010916577,0.000011251612,0.0000023755802,0.000042825064,0.0003398492,0.99449414,0.000050226095,0.000006461527,0.00037128187],"study_design_scores_gemma":[0.00030732958,0.0001183618,0.029911283,0.000018463927,0.0000072192015,0.00038370173,0.00003673938,0.0005268257,0.9674689,0.00005758275,0.0010941917,0.000069394875],"about_ca_topic_score_codex":0.000011783639,"about_ca_topic_score_gemma":6.657279e-7,"teacher_disagreement_score":0.027025243,"about_ca_system_score_codex":0.000015798554,"about_ca_system_score_gemma":0.00040498527,"threshold_uncertainty_score":0.25320333},"labels":[],"label_agreement":null},{"id":"W2017190184","doi":"10.1016/j.vascn.2009.12.001","title":"Methodological considerations for improving Western blot analysis","year":2009,"lang":"en","type":"review","venue":"Journal of Pharmacological and Toxicological Methods","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":128,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"Blot; Western blot; Nitrocellulose; Graduate students; Computational biology; Chemistry; Antiserum; Data science; Molecular biology; Biology; Computer science; Antigen; Biochemistry; Membrane; Medicine; Immunology; Medical education","score_opus":0.3957699364793915,"score_gpt":0.5526137016227338,"score_spread":0.1568437651433423,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017190184","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022490103,0.825297,0.1730293,0.0002603257,0.0002019787,0.0008649379,0.00004799824,0.000014205288,0.00005934906],"genre_scores_gemma":[0.00046239418,0.68512225,0.31316778,0.0005819528,0.00045287577,0.000103238715,0.000018495093,0.00001142515,0.00007956986],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9927902,0.0044376464,0.0015523493,0.00065670104,0.00018153393,0.00038154706],"domain_scores_gemma":[0.9943942,0.0033696163,0.0013101196,0.00022505065,0.00032875186,0.00037226704],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.006458215,0.0004665142,0.002667757,0.00021572008,0.00019457171,0.00008722617,0.00037339784,0.0010286454,0.00017935234],"category_scores_gemma":[0.007289373,0.00027323223,0.0017361024,0.0003380701,0.00027686122,0.000009646395,0.0001817758,0.00071511517,9.2640596e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014255953,0.00042693617,0.000013034493,0.00041236138,0.0014689412,0.000018917613,0.0000055753003,0.000008297756,0.005489668,0.00026768382,0.0001303113,0.9916157],"study_design_scores_gemma":[0.0008264302,0.0035073056,0.00023562141,0.00007273486,0.012577073,0.0003127881,0.000009556466,0.00004894041,0.0012367308,0.0043522376,0.9762876,0.00053299085],"about_ca_topic_score_codex":2.9963232e-7,"about_ca_topic_score_gemma":7.5886516e-7,"teacher_disagreement_score":0.9910827,"about_ca_system_score_codex":0.00004635071,"about_ca_system_score_gemma":0.00020656495,"threshold_uncertainty_score":0.999972},"labels":[],"label_agreement":null},{"id":"W2017409119","doi":"10.1016/j.ymeth.2004.08.020","title":"Biomarker discovery in biological fluids","year":2005,"lang":"en","type":"article","venue":"Methods","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Caprion (Canada)","funders":"","keywords":"Biomarker discovery; Biomarker; Computational biology; Drug discovery; Prioritization; Identification (biology); Drug development; Proteomics; Biology; Bioinformatics; Drug; Pharmacology; Genetics","score_opus":0.05483947805572032,"score_gpt":0.39413719044187945,"score_spread":0.33929771238615913,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017409119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7316901,0.0027443452,0.2597519,0.0008138408,0.000093036506,0.00017924432,0.000008046368,0.000016027845,0.004703449],"genre_scores_gemma":[0.8385011,0.00011137583,0.16024707,0.00033426099,0.000077288125,0.000032547803,0.000026361935,0.000005389171,0.0006646248],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99902993,0.00038132668,0.00015781367,0.00025240064,0.000038730603,0.0001397976],"domain_scores_gemma":[0.9996246,0.000023046647,0.000021309024,0.00027948947,0.000016188578,0.000035336383],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009756705,0.000074878524,0.00008868372,0.000025464475,0.000021621658,0.000013271897,0.000121312696,0.000121261386,0.00005576707],"category_scores_gemma":[0.00031343757,0.000059735205,0.000053344105,0.00008325902,0.00006622177,0.0000035726575,0.0000617106,0.00005533645,0.0000103740795],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042311876,0.000065882625,0.00763456,0.0000021218893,0.0000049639134,3.2503561e-7,0.000012435648,0.0000028721504,0.81748736,0.0003375598,0.00013101105,0.17427859],"study_design_scores_gemma":[0.000294413,0.000053259242,0.097348005,0.0000020495424,0.0000016589939,0.0000033547983,0.0000178322,0.00018848809,0.44214576,0.00045010756,0.45935744,0.00013762282],"about_ca_topic_score_codex":0.0000054765483,"about_ca_topic_score_gemma":0.000010024764,"teacher_disagreement_score":0.45922643,"about_ca_system_score_codex":0.000013381014,"about_ca_system_score_gemma":0.000022650825,"threshold_uncertainty_score":0.2435931},"labels":[],"label_agreement":null},{"id":"W2017414584","doi":"10.1002/jps.22282","title":"Application of Extrinsic Fluorescence Spectroscopy for the High Throughput Formulation Screening of Aluminum-Adjuvanted Vaccines","year":2010,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Antigenicity; Chemistry; Adsorption; Antigen; High-throughput screening; Fluorescence spectroscopy; Hydroxide; Chromatography; Fluorescence; Biochemistry; Organic chemistry; Biology; Immunology","score_opus":0.032470199145694975,"score_gpt":0.36678053282813844,"score_spread":0.33431033368244345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017414584","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7614332,0.000586911,0.23623393,0.0012416161,0.00016784189,0.00028829832,0.0000075720995,0.0000019647237,0.000038702125],"genre_scores_gemma":[0.97805226,0.00011195835,0.021631889,0.00003822402,0.00015163577,0.0000055716505,0.0000016806024,0.0000025575857,0.0000042521774],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991667,0.00003118416,0.0003537508,0.00011895945,0.00021941066,0.00010995688],"domain_scores_gemma":[0.99906117,0.00010458214,0.00035687294,0.00012897965,0.00030323968,0.000045130946],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011122643,0.00005903821,0.000113393995,0.000030139781,0.00009308834,0.00001103007,0.00032617257,0.0000478874,0.000014643211],"category_scores_gemma":[0.00035770575,0.000036124176,0.00008280315,0.00015786833,0.00024210429,0.00001741653,0.000031311516,0.00009990827,1.7006953e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013925752,0.000050687308,0.0051458203,0.000014675369,0.000011426587,3.2899443e-8,0.000018235714,0.000058571437,0.9588245,0.0020604217,0.000020778758,0.033655595],"study_design_scores_gemma":[0.0004283078,0.00021710525,0.023038808,0.0000068833547,0.000024818048,0.0000063082334,0.000046439334,0.009434893,0.9624309,0.0008230198,0.003498416,0.00004410254],"about_ca_topic_score_codex":0.000008886771,"about_ca_topic_score_gemma":0.0000069123644,"teacher_disagreement_score":0.21661907,"about_ca_system_score_codex":0.0000038260573,"about_ca_system_score_gemma":0.0000687622,"threshold_uncertainty_score":0.14731011},"labels":[],"label_agreement":null},{"id":"W2018911791","doi":"10.1002/apj.5500130112","title":"Fractionation of Proteins Using Ultrafiltration: Developments and Challenges","year":2005,"lang":"en","type":"article","venue":"Developments in Chemical Engineering and Mineral Processing","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Engineering and Physical Sciences Research Council","keywords":"Ultrafiltration (renal); Fractionation; Separation method; Throughput; High resolution; Chemistry; Selectivity; Resolution (logic); Chromatography; Nanotechnology; Biochemical engineering; Computer science; Materials science; Engineering; Biochemistry; Artificial intelligence; Telecommunications; Geography","score_opus":0.02112128983784682,"score_gpt":0.2453241539065091,"score_spread":0.2242028640686623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018911791","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994441,0.0028185667,0.0023264994,0.00012700581,0.000015776472,0.00011034196,0.000001118753,0.000009544316,0.00015014781],"genre_scores_gemma":[0.9295775,0.00023099029,0.07008517,0.000020356654,0.000029641144,0.000017227569,0.000015683137,0.0000072034677,0.000016168655],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99940586,0.0000065008885,0.00020309792,0.00019828671,0.000080884245,0.000105350286],"domain_scores_gemma":[0.9998161,0.0000052002524,0.00004635343,0.00004814089,0.00004610669,0.00003805404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012619019,0.00009166606,0.000088803936,0.000045099216,0.000025597774,0.000011065085,0.0000380188,0.000083575396,9.795197e-7],"category_scores_gemma":[0.00009118465,0.00009527456,0.000007873418,0.000059537848,0.000026736425,0.000018088831,0.000026329984,0.000059358346,1.0732762e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000139198455,0.0000368654,0.0012543537,0.00015283578,0.0000074756103,1.6332385e-7,0.00022477539,0.0002289171,0.9170231,0.000049054925,8.9852085e-7,0.08100762],"study_design_scores_gemma":[0.000718961,0.000017215792,0.023831302,0.00015496148,0.0000045855386,0.00002375579,0.00006149902,0.008289284,0.9571371,0.000022510978,0.009434755,0.00030405528],"about_ca_topic_score_codex":0.0000021716965,"about_ca_topic_score_gemma":0.0000014755553,"teacher_disagreement_score":0.080703564,"about_ca_system_score_codex":0.000023493421,"about_ca_system_score_gemma":0.000053402142,"threshold_uncertainty_score":0.38851836},"labels":[],"label_agreement":null},{"id":"W2019760779","doi":"10.1021/bp070173t","title":"A Study of the Interaction of HEK-293 Cells with Streamline Chelating Adsorbent in Expanded Bed Operation","year":2008,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Polytechnique Montréal","funders":"","keywords":"Adsorption; Chromatography; Chemistry; HEK 293 cells; Centrifugation; Expanded bed adsorption; Chelation; Filtration (mathematics); Chemical engineering; Biochemistry; Organic chemistry","score_opus":0.016538275752624815,"score_gpt":0.2650939654222907,"score_spread":0.24855568966966587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019760779","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987433,0.00020180868,0.000105856074,0.00020156775,0.000033464712,0.0006788441,0.00000385291,0.000012179696,0.000019134352],"genre_scores_gemma":[0.99937534,0.000029428718,0.00048303846,0.0000064691794,0.0000082850975,0.00006901159,0.000008456265,0.0000060056045,0.000013970421],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992691,0.00007830005,0.0002562111,0.00021585805,0.00008846958,0.00009203653],"domain_scores_gemma":[0.99934393,0.0000050221875,0.00017714458,0.00039555915,0.00006713743,0.00001120111],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012410358,0.00008215081,0.00012752338,0.000050740782,0.00004209746,0.0000020733387,0.00016729176,0.00017431293,0.0000029012824],"category_scores_gemma":[0.000039482984,0.000056736786,0.000024791849,0.00015939132,0.00021665759,0.000003919861,0.00008089067,0.000113692506,2.7946194e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026447486,0.0013859563,0.21611999,0.000022393166,0.00004085475,0.000001975754,0.0005708031,0.000130614,0.77548504,0.000059760696,0.0000044180647,0.005913717],"study_design_scores_gemma":[0.0009164389,0.00072083744,0.026436813,0.000015886628,0.000006517757,0.0000095568785,0.0010552178,0.00011629988,0.9705883,0.0000049907153,0.000067968525,0.00006116501],"about_ca_topic_score_codex":0.000033024866,"about_ca_topic_score_gemma":0.00018393228,"teacher_disagreement_score":0.19510327,"about_ca_system_score_codex":0.0000130237595,"about_ca_system_score_gemma":0.000042761134,"threshold_uncertainty_score":0.23136589},"labels":[],"label_agreement":null},{"id":"W2020239267","doi":"10.1007/s12010-009-8625-9","title":"Activation and Stabilization of The Hydroperoxide Lyase Enzymatic Extract from Mint Leaves (Mentha spicata) Using Selected Chemical Additives","year":2009,"lang":"en","type":"article","venue":"Applied Biochemistry and Biotechnology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Enzyme; Glycine; Thermal stability; Chromatography; Dextran; Lyase; Biochemistry; Organic chemistry; Amino acid","score_opus":0.0073811529723570145,"score_gpt":0.21707593336043118,"score_spread":0.20969478038807418,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020239267","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99738157,0.0003974116,0.0012136867,0.00064181275,0.000008716332,0.00024079852,0.0000416185,0.000022146616,0.000052245654],"genre_scores_gemma":[0.99794567,0.000096278236,0.0016803542,0.000085160566,0.00003232033,0.000011663775,0.00013452797,0.000006508758,0.0000075442963],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991256,0.000023467624,0.0002370572,0.00039539795,0.00007998335,0.00013847661],"domain_scores_gemma":[0.9993723,0.000018776936,0.00015884041,0.0003666463,0.00004476216,0.000038682625],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000079866724,0.00014868201,0.00014729954,0.000020766445,0.00007572894,0.000011186945,0.00014984616,0.00040240854,0.000007926685],"category_scores_gemma":[0.00018025757,0.00011818923,0.000027668795,0.00015259377,0.00037386394,0.000004798838,0.00008815331,0.00013038475,2.2048705e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000070918955,0.0000856485,0.00030327588,0.000021880802,0.00001814698,9.3932485e-8,0.00002483284,0.0000010504149,0.9919883,0.00018157125,0.000012216892,0.0072920676],"study_design_scores_gemma":[0.00030496196,0.0000411592,0.003571187,0.000018323757,0.000018913295,0.000006073349,0.00013887306,0.00012397056,0.99496317,0.00047150115,0.00020874554,0.00013310995],"about_ca_topic_score_codex":0.000011105613,"about_ca_topic_score_gemma":0.0000015063528,"teacher_disagreement_score":0.0071589574,"about_ca_system_score_codex":0.00001720003,"about_ca_system_score_gemma":0.00004771365,"threshold_uncertainty_score":0.4819617},"labels":[],"label_agreement":null},{"id":"W2020665256","doi":"10.1016/j.chroma.2010.06.061","title":"Fractionation of different PEGylated forms of a protein by chromatography using environment-responsive membranes","year":2010,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Chemistry; PEGylation; Chromatography; Fractionation; Lysozyme; Hydrophilic interaction chromatography; Ultrafiltration (renal); Membrane; High-performance liquid chromatography; Polyethylene glycol; Biochemistry","score_opus":0.005724043579118659,"score_gpt":0.23100638277013907,"score_spread":0.22528233919102042,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020665256","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99589854,0.0010866849,0.002493939,0.00007642074,0.00006623031,0.0002832007,0.00003795879,0.0000036111048,0.0000534198],"genre_scores_gemma":[0.9982638,0.00015977582,0.0014867674,0.000012841556,0.000030122594,0.00000849153,0.000020553343,0.00001269227,0.0000049588175],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99868107,0.00008630245,0.00063587923,0.0001506262,0.0003192148,0.0001268849],"domain_scores_gemma":[0.9983906,0.000019199155,0.0010116431,0.0002659639,0.00022894061,0.00008362644],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030514822,0.00014445889,0.0002772334,0.0002411553,0.000048776932,0.000010416874,0.00018776942,0.00017439088,0.000061497696],"category_scores_gemma":[0.00008121848,0.00011577922,0.00035595978,0.00018663841,0.00021568047,0.000021665723,0.000027040654,0.00017393615,2.3172177e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025133914,0.0003660176,0.007674041,0.00007262856,0.00016331003,6.3082956e-7,0.000052063322,0.000009414841,0.9908777,0.00009153553,0.000028670827,0.0004126379],"study_design_scores_gemma":[0.00081732473,0.00036557927,0.021229906,0.000037825288,0.000040213796,0.000043744687,0.00007311617,0.000054756685,0.97404444,0.0005191563,0.00265647,0.0001174689],"about_ca_topic_score_codex":0.0000066468524,"about_ca_topic_score_gemma":0.000002866639,"teacher_disagreement_score":0.016833272,"about_ca_system_score_codex":0.0000067530336,"about_ca_system_score_gemma":0.00006202303,"threshold_uncertainty_score":0.47213396},"labels":[],"label_agreement":null},{"id":"W2020683193","doi":"10.4236/abb.2013.46094","title":"Preliminary study of binary protein adsorption system and potential bioseparation under homogeneous field of shear in airlift biocontactor","year":2013,"lang":"en","type":"article","venue":"Advances in Bioscience and Biotechnology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Adsorption; Bovine serum albumin; Chemistry; Chromatography; Pulmonary surfactant; Protein adsorption; Globular protein; Chemical engineering; Organic chemistry; Crystallography; Biochemistry","score_opus":0.005327957867544724,"score_gpt":0.2526055474176372,"score_spread":0.24727758955009246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020683193","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960377,0.0023374995,0.000474252,0.00027310548,0.000036375783,0.0008181353,0.0000037300358,0.000008693457,0.000010506808],"genre_scores_gemma":[0.9989679,0.0004975078,0.00042666768,0.000014967602,0.000005534538,0.0000756466,0.0000029729795,0.0000029097723,0.000005923058],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991405,0.000057368452,0.0002747177,0.00032836612,0.00007253323,0.00012651706],"domain_scores_gemma":[0.9996075,0.00000892524,0.00011253204,0.00021370087,0.00003679275,0.00002055801],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015573825,0.000086693995,0.00014477439,0.00015842402,0.000025632493,0.0000053957165,0.00012723853,0.000204066,0.000001753797],"category_scores_gemma":[0.000047286576,0.000074870084,0.000013177765,0.00023255248,0.00025762382,0.000026238538,0.000096978176,0.000071016344,3.4497748e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000086996,0.00025852394,0.009856834,0.00005881772,0.0000022365093,9.2414194e-7,0.00006134811,0.000024515522,0.9819122,0.00025387338,5.5256265e-7,0.007483197],"study_design_scores_gemma":[0.0007643728,0.004086163,0.091130756,0.00005137705,0.0000039760635,0.000014104265,0.0025741037,0.0006726303,0.90029097,0.00021254142,0.000062470725,0.0001365369],"about_ca_topic_score_codex":0.00015689289,"about_ca_topic_score_gemma":0.000106331536,"teacher_disagreement_score":0.081621215,"about_ca_system_score_codex":0.000009753562,"about_ca_system_score_gemma":0.000021276805,"threshold_uncertainty_score":0.30531135},"labels":[],"label_agreement":null},{"id":"W2020757086","doi":"10.1016/j.colsurfb.2006.04.019","title":"Protein adsorption from flowing solutions on pure and maleic acid copolymer modified glass particles","year":2006,"lang":"en","type":"article","venue":"Colloids and Surfaces B Biointerfaces","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Adsorption; Copolymer; Maleic acid; Chemical engineering; Protein adsorption; Materials science; Particle (ecology); Surface charge; Human serum albumin; Polymer chemistry; Chemistry; Chromatography; Polymer; Organic chemistry; Composite material; Physical chemistry","score_opus":0.014205743013013555,"score_gpt":0.2262618770401473,"score_spread":0.21205613402713375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020757086","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9873342,0.010058707,0.00094610755,0.0006376411,0.00006928668,0.000382341,0.00012446496,0.000032365428,0.0004148792],"genre_scores_gemma":[0.9985981,0.00015869027,0.0005218388,0.000051604296,0.000060198385,0.000052504714,0.00007644472,0.000013353515,0.00046726776],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988658,0.000095732685,0.00022650245,0.0004587136,0.00011514891,0.00023814641],"domain_scores_gemma":[0.9995567,0.000014700595,0.00005060485,0.00025400298,0.000045625427,0.000078337274],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018136401,0.00018286535,0.00016189404,0.000029519208,0.0001978077,0.00010727517,0.00009703047,0.00014443792,0.000019017829],"category_scores_gemma":[0.00003635834,0.00016064293,0.00004652619,0.000067313114,0.00020020004,0.000014343154,0.000083326726,0.00008087769,0.0000062145946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013556576,0.00007611009,0.0042405617,0.000014282802,0.000024260275,4.6596432e-7,0.000037411082,0.000059883037,0.99324787,0.00051261834,0.00012592651,0.0015250742],"study_design_scores_gemma":[0.0007014713,0.0002573841,0.015627848,0.000037864156,0.00001814889,0.0000021527576,0.00018866792,0.0024753697,0.97630864,0.0009254568,0.0031952874,0.00026168724],"about_ca_topic_score_codex":0.00020510287,"about_ca_topic_score_gemma":0.00033501643,"teacher_disagreement_score":0.016939178,"about_ca_system_score_codex":0.000012750509,"about_ca_system_score_gemma":0.000026811815,"threshold_uncertainty_score":0.6550828},"labels":[],"label_agreement":null},{"id":"W2021459329","doi":"10.1016/j.chroma.2012.11.052","title":"Determination of competitive adsorption isotherm of enantiomers on preparative chromatographic columns using inverse method","year":2012,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Adsorption; Langmuir adsorption model; Dispersion (optics); Chromatography; Mass transfer; Particle swarm optimization; Inverse; Parametric statistics; Sorting; Algorithm; Mathematics; Statistics; Physics","score_opus":0.020280899561504487,"score_gpt":0.3135188555260733,"score_spread":0.2932379559645688,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021459329","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9743495,0.00056908635,0.024237867,0.000012732926,0.00010296167,0.00020368812,0.00002320391,0.0000029782843,0.0004979545],"genre_scores_gemma":[0.9816927,0.00012270255,0.018080933,0.00002496477,0.00005460268,0.000004056453,0.000006481602,0.000010141857,0.0000034714415],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99869376,0.00029150234,0.00052773784,0.000114630595,0.00023413304,0.00013822073],"domain_scores_gemma":[0.9982827,0.00003770624,0.0010416119,0.00019453233,0.0003620516,0.00008142574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00073442736,0.00011729616,0.00027407997,0.00031312302,0.000031727937,0.000005376697,0.00012597741,0.00011665436,0.000020408017],"category_scores_gemma":[0.0000818794,0.00010540516,0.00032012814,0.00034897728,0.00018784995,0.0000250861,0.000018353248,0.000083948005,3.299441e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024388544,0.0004187298,0.017142555,0.00007608589,0.00013798689,3.8163606e-7,0.00050985184,0.000022182636,0.97986096,0.0006228368,0.000022232134,0.0009423095],"study_design_scores_gemma":[0.00091130106,0.0008779381,0.041448098,0.00014081562,0.00008976835,0.00005929562,0.0006049323,0.00028221318,0.9543076,0.0001893265,0.00094410917,0.000144588],"about_ca_topic_score_codex":0.0000089605455,"about_ca_topic_score_gemma":0.0000064196984,"teacher_disagreement_score":0.025553346,"about_ca_system_score_codex":0.000014737508,"about_ca_system_score_gemma":0.000071305505,"threshold_uncertainty_score":0.42982978},"labels":[],"label_agreement":null},{"id":"W2023039536","doi":"10.1002/cjce.22182","title":"Effect of fluid velocity on radioactive ion retention by fluidized‐bed reactor","year":2015,"lang":"en","type":"article","venue":"The Canadian Journal of Chemical Engineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Adsorption; Mass transfer; Fluidized bed; Diffusion; Particle (ecology); Mechanics; Materials science; Volumetric flow rate; Flow (mathematics); Flow velocity; Column (typography); Chemistry; Thermodynamics; Chromatography; Mathematics; Physics","score_opus":0.008421804926124188,"score_gpt":0.21121291456501814,"score_spread":0.20279110963889396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023039536","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984944,0.0007042234,0.00030996854,0.00020790906,0.00012262871,0.00008639414,0.000012023013,0.0000022406111,0.000060197894],"genre_scores_gemma":[0.9997541,0.0000045495667,0.00008867679,0.000020291714,0.000102820886,0.0000024944673,0.00001272524,0.000008252225,0.0000060968273],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99945086,0.000056178917,0.00018186451,0.00007779332,0.00011597071,0.00011732274],"domain_scores_gemma":[0.99936897,0.000029381437,0.00008673802,0.00015313138,0.000113060174,0.0002487435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00064141187,0.00007988245,0.00012816227,0.000029540868,0.000015368492,0.00000882783,0.00015450425,0.00008909672,0.0000039719584],"category_scores_gemma":[0.0008719882,0.00005843997,0.00007804303,0.00005536126,0.000046645782,0.000004434399,0.0000069103967,0.00014493079,6.3465546e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014567377,0.0000051583793,0.000029275723,0.000010555336,0.000025415959,8.7278175e-7,0.0000328185,0.00007437803,0.99821204,0.000022813927,0.0006429549,0.0007980491],"study_design_scores_gemma":[0.00041865566,0.00026068406,0.000016036407,0.000017614675,0.000012962795,0.000014478867,0.0000031066354,0.00018888609,0.9970732,0.000012282183,0.0019252364,0.00005686304],"about_ca_topic_score_codex":0.00013816981,"about_ca_topic_score_gemma":0.0000085322245,"teacher_disagreement_score":0.0012822816,"about_ca_system_score_codex":0.00010858036,"about_ca_system_score_gemma":0.00017139027,"threshold_uncertainty_score":0.23831129},"labels":[],"label_agreement":null},{"id":"W2023516840","doi":"10.1016/j.clinbiochem.2008.08.020","title":"Analytical evaluation of C-peptide immunoassay on Immulite 2500","year":2008,"lang":"en","type":"article","venue":"Clinical Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Hamilton Regional Laboratory Medicine Program; Hamilton General Hospital","funders":"","keywords":"Proinsulin; Insulin; Immunoassay; Internal medicine; Endocrinology; Chemistry; Bovine serum albumin; Overweight; Monoclonal antibody; Antibody; Medicine; Obesity; Chromatography; Immunology","score_opus":0.09692437889670319,"score_gpt":0.3985348016973073,"score_spread":0.3016104228006041,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023516840","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987949,0.00097563455,0.00009854538,0.0002093038,0.000101255086,0.00018747154,0.000028359835,0.000012899517,0.010437502],"genre_scores_gemma":[0.9980643,0.00020625138,0.00024818405,0.000201264,0.00020336914,0.000024140725,0.00018321034,0.000011800156,0.00085750927],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99801767,0.00022431034,0.00067088415,0.00051633344,0.0003934362,0.00017735381],"domain_scores_gemma":[0.9982494,0.00007971144,0.00018868639,0.0009566825,0.00039948855,0.00012600643],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018382387,0.00014619187,0.0002302352,0.00001732749,0.00006362355,0.0000051427464,0.00026424538,0.00032953822,0.00014102184],"category_scores_gemma":[0.0030426036,0.00013632239,0.0002673517,0.00009853585,0.0004561748,0.0000022297008,0.00007615577,0.00019761141,0.00003535752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009831907,0.0020907354,0.06913627,0.00007648638,0.00028471233,0.00000483744,0.00003389745,0.000058470538,0.8819244,0.00020904119,0.007927688,0.037270293],"study_design_scores_gemma":[0.0016613944,0.0003495461,0.066085026,0.000024630384,0.00006275041,0.000013375738,0.000028942091,0.00063940766,0.91708255,0.0001601547,0.013613325,0.0002789018],"about_ca_topic_score_codex":0.0000030296274,"about_ca_topic_score_gemma":3.7923596e-7,"teacher_disagreement_score":0.03699139,"about_ca_system_score_codex":0.000026478947,"about_ca_system_score_gemma":0.00030576705,"threshold_uncertainty_score":0.55590653},"labels":[],"label_agreement":null},{"id":"W2023880129","doi":"10.1007/s11005-011-0482-0","title":"Review of AdS/CFT Integrability, Chapter III.3: The Dressing Factor","year":2011,"lang":"en","type":"article","venue":"Letters in Mathematical Physics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Perimeter Institute","funders":"","keywords":"Complex system; Calculus (dental); Factor (programming language)","score_opus":0.04741394669795971,"score_gpt":0.2810200093188243,"score_spread":0.2336060626208646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023880129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8321742,0.0078025437,0.12687422,0.0066987285,0.00018418797,0.0022457873,0.000033038352,0.000043343425,0.023943955],"genre_scores_gemma":[0.99435365,0.00027603834,0.0023650012,0.002900433,0.000040662755,0.000030777846,0.0000055909645,0.000009781129,0.00001807245],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923426,0.000071201575,0.0002950995,0.00017615246,0.000104267594,0.00011903699],"domain_scores_gemma":[0.99928546,0.000030858904,0.00009279604,0.00052518945,0.000039277937,0.00002642793],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028695754,0.00009924757,0.0001732859,0.000007134951,0.00002249556,0.0000046571217,0.00023943745,0.000043455988,0.00014870615],"category_scores_gemma":[0.00015484582,0.00006476786,0.00010018132,0.00005604212,0.00022617816,0.0000041121175,0.00007763553,0.00011567182,0.000012794927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018221707,0.0022698697,0.0064520957,0.016033377,0.00019309466,0.000004311088,0.0048616403,0.0000023145303,0.66353446,0.21397677,0.0023163853,0.09017348],"study_design_scores_gemma":[0.0012748492,0.00025831102,0.008695105,0.006613215,0.000101989266,0.000011268148,0.00022345428,0.0003913803,0.74553,0.22421105,0.011600187,0.0010891854],"about_ca_topic_score_codex":0.000006110396,"about_ca_topic_score_gemma":0.0000010533473,"teacher_disagreement_score":0.16217944,"about_ca_system_score_codex":0.00000731877,"about_ca_system_score_gemma":0.000010975107,"threshold_uncertainty_score":0.2641157},"labels":[],"label_agreement":null},{"id":"W2029770669","doi":"10.1081/ss-120019406","title":"Comparison of Two Methods to Recover Lysozyme from Reverse Micellar Phases","year":2003,"lang":"en","type":"article","venue":"Separation Science and Technology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Lysozyme; Chemistry; Pulmonary surfactant; Chromatography; Micelle; Micellar solutions; Cationic polymerization; Solvent; Aqueous solution; Micellar liquid chromatography; Acetone; Phase (matter); Aqueous two-phase system; Precipitation; Organic chemistry; Biochemistry","score_opus":0.036659188519416824,"score_gpt":0.44675385824892194,"score_spread":0.41009466972950515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029770669","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9506709,0.00078653573,0.046335403,0.00050070806,0.000081178274,0.0001904228,0.000009127298,0.000014540233,0.0014111598],"genre_scores_gemma":[0.9494134,0.00001981109,0.050293826,0.00014074285,0.0000075251314,0.000013986563,0.0000063398775,0.000002291635,0.000102041806],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99921864,0.00005572305,0.00018343916,0.00032211514,0.000103769766,0.00011632126],"domain_scores_gemma":[0.99929917,0.000014300769,0.00007582203,0.0003312818,0.00023306959,0.00004638622],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006383004,0.00006251385,0.000116149036,0.00011666763,0.00008972819,0.000012920664,0.00015926428,0.00008339904,0.000028993885],"category_scores_gemma":[0.0007974604,0.00005902788,0.000014290028,0.00052944326,0.00036667776,0.000008212666,0.000046078185,0.000043413223,0.000005210323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009091626,0.000034531015,0.005163777,0.0000010895913,0.000003120117,5.6302607e-8,0.000043900825,0.0000053045555,0.98259175,0.0026239944,0.00022339828,0.0092999805],"study_design_scores_gemma":[0.00016042612,0.00010773418,0.00031944527,0.0000017140875,0.0000040916552,0.000001264191,0.00015137267,0.00007586635,0.9002571,0.0022064105,0.09665149,0.0000630552],"about_ca_topic_score_codex":0.000014341271,"about_ca_topic_score_gemma":0.000023232487,"teacher_disagreement_score":0.09642809,"about_ca_system_score_codex":0.000011053032,"about_ca_system_score_gemma":0.00012056498,"threshold_uncertainty_score":0.24070871},"labels":[],"label_agreement":null},{"id":"W2030127546","doi":"10.1002/btpr.501","title":"Enzymatic fragmentation of cation exchange membrane bound immunoglobulin G","year":2010,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Membrane; Fragmentation (computing); Chromatography; Microporous material; Enzyme; Steric effects; Macromolecule; Reaction rate constant; Stereochemistry; Organic chemistry; Kinetics; Biochemistry","score_opus":0.0070343931608231,"score_gpt":0.2586746231153163,"score_spread":0.2516402299544932,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030127546","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99576044,0.0016342463,0.0007967756,0.0010137286,0.00016753434,0.00041251385,0.000015168949,0.00004847589,0.0001511175],"genre_scores_gemma":[0.99555755,0.00012174634,0.0039106584,0.00003484994,0.000041895335,0.0001119149,0.00012129122,0.0000102130225,0.00008989046],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992313,0.00003763006,0.00023720172,0.00025630405,0.000092047696,0.00014556399],"domain_scores_gemma":[0.99914676,0.000005659522,0.0001645159,0.00056236103,0.00009303223,0.000027700047],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025326526,0.000101140795,0.000114787275,0.00006698023,0.00006043606,0.000009977159,0.0002468439,0.0004524136,0.000056035817],"category_scores_gemma":[0.00011569625,0.00009900498,0.00004351888,0.00013005197,0.00042017037,0.0000046118907,0.000072640476,0.00013984473,0.000011360365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003639985,0.00011549708,0.0022199114,0.000055476394,0.000020660187,3.1579137e-7,0.00003861966,2.938041e-7,0.9694741,0.0016958803,0.000040104896,0.026302777],"study_design_scores_gemma":[0.00033509423,0.00012928482,0.007326194,0.0000054021566,0.00000963231,0.000008842661,0.0000451348,0.000029188428,0.97767276,0.00022574536,0.014110444,0.00010230626],"about_ca_topic_score_codex":0.000012222201,"about_ca_topic_score_gemma":0.00003808032,"teacher_disagreement_score":0.026200471,"about_ca_system_score_codex":0.000007845509,"about_ca_system_score_gemma":0.00004508679,"threshold_uncertainty_score":0.4037306},"labels":[],"label_agreement":null},{"id":"W2031051143","doi":"10.1021/la900365g","title":"Interaction of an Antimicrobial Peptide with a Model Lipid Bilayer Using Molecular Dynamics Simulation","year":2009,"lang":"en","type":"article","venue":"Langmuir","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Molecular dynamics; Lipid bilayer; Peptide; Antimicrobial; Chemistry; Dynamics (music); Bilayer; Antimicrobial peptides; Nanotechnology; Biophysics; Chemical physics; Materials science; Physics; Biochemistry; Computational chemistry; Membrane; Biology; Organic chemistry","score_opus":0.014468470159499477,"score_gpt":0.28662211466453846,"score_spread":0.272153644505039,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031051143","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8645157,0.000012841257,0.13499908,0.00006187282,0.000011752421,0.00010430009,0.000012960377,0.000009630056,0.00027184183],"genre_scores_gemma":[0.99269634,0.0000013554959,0.006948591,0.0001383048,0.000032605203,0.0000014815822,0.0001400865,0.000007864545,0.00003334317],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9995373,0.000029553954,0.00011697128,0.00017076022,0.00006196788,0.000083446495],"domain_scores_gemma":[0.99961543,0.0000017576837,0.00007162228,0.00020549828,0.00007969393,0.000025996871],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006206737,0.00007291806,0.000075360134,0.000026228638,0.000029472925,0.000009699241,0.00006425879,0.00006847521,0.000002641349],"category_scores_gemma":[0.000012211568,0.00006547739,0.000032184584,0.000053554948,0.000022535689,0.000008790749,0.000010556364,0.00004210282,5.19817e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014670906,0.00008677792,0.00022269014,0.000007926288,0.00000746048,5.302598e-7,0.00005507378,0.17090695,0.8266968,0.00010753449,0.00000241986,0.0017591167],"study_design_scores_gemma":[0.0002721865,0.00014304723,0.0012000193,0.0000076169445,0.000011289386,0.0000052803157,0.00002356021,0.694255,0.3037662,0.0000617578,0.0001506669,0.000103419276],"about_ca_topic_score_codex":0.000011497994,"about_ca_topic_score_gemma":0.0000183549,"teacher_disagreement_score":0.52334803,"about_ca_system_score_codex":0.0000224467,"about_ca_system_score_gemma":0.000037573038,"threshold_uncertainty_score":0.26700905},"labels":[],"label_agreement":null},{"id":"W2032649102","doi":"10.1016/s0301-4622(00)00144-7","title":"Analytical ultracentrifugation and the characterization of chromatin structure","year":2000,"lang":"en","type":"review","venue":"Biophysical Chemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"Medical Research Council Canada","keywords":"Ultracentrifuge; Analytical Ultracentrifugation; Chemistry; Characterization (materials science); Chromatin; Sedimentation; Polyelectrolyte; Macromolecule; Polymer science; Nanotechnology; Chromatography; Polymer; Biochemistry; Organic chemistry; DNA; Biology; Materials science","score_opus":0.00937047263512452,"score_gpt":0.26235240382542885,"score_spread":0.2529819311903043,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2032649102","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.032928683,0.96544313,0.00003798721,0.00005985814,0.000030213712,0.00066293916,0.00047580458,0.000012861903,0.0003485048],"genre_scores_gemma":[0.030268976,0.96705145,0.000019591696,0.000013784861,0.00029992522,0.00003457767,0.0020390316,0.000018096944,0.00025458515],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989875,0.00009003925,0.0003619174,0.00032672082,0.00012319973,0.000110599605],"domain_scores_gemma":[0.99922997,0.000025054864,0.00023915191,0.00041269982,0.000041153024,0.000051978892],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000835573,0.00020753614,0.000532261,0.000008337455,0.000041710955,0.000019067687,0.0001831347,0.0003298029,0.00007187712],"category_scores_gemma":[0.00008281727,0.00013374421,0.00020998759,0.0001045463,0.0003482484,0.0000022335912,0.00004161096,0.0001593454,0.000002323352],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013295066,0.00013167586,0.0000040113796,0.009745854,0.00018940456,5.269558e-7,0.000022813625,2.2637226e-7,0.29486895,0.00027496857,0.000033945213,0.6945947],"study_design_scores_gemma":[0.0005078038,0.000020689275,0.000049151924,0.0004789036,0.00031010137,0.000014440204,0.00000308013,0.000051116665,0.063383676,0.0000505959,0.9348479,0.00028257002],"about_ca_topic_score_codex":0.0000010943907,"about_ca_topic_score_gemma":6.618596e-8,"teacher_disagreement_score":0.9348139,"about_ca_system_score_codex":0.000011023956,"about_ca_system_score_gemma":0.000090499336,"threshold_uncertainty_score":0.54539305},"labels":[],"label_agreement":null},{"id":"W2035678900","doi":"10.1016/j.memsci.2011.11.049","title":"Simultaneous removal of leached protein-A and aggregates from monoclonal antibody using hydrophobic interaction membrane chromatography","year":2011,"lang":"en","type":"article","venue":"Journal of Membrane Science","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Hydrophilic interaction chromatography; Chemistry; Monoclonal antibody; Membrane; Chromatography; Hydrophobic effect; Antibody; Biochemistry; High-performance liquid chromatography; Biology","score_opus":0.022391804919147235,"score_gpt":0.28259621448868216,"score_spread":0.26020440956953494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035678900","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99739486,0.0013841173,0.0007321829,0.00002971202,0.0001257024,0.00014123274,0.0000064552255,0.0000035379378,0.00018220695],"genre_scores_gemma":[0.9885364,0.0001772845,0.0111891115,0.000016845705,0.000059177186,8.056831e-7,0.000002660894,0.000006913907,0.000010800779],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987921,0.0000717527,0.00042557294,0.00024711524,0.0003062615,0.00015721217],"domain_scores_gemma":[0.99878836,0.00002208397,0.0005276905,0.00023395702,0.00030903332,0.00011884892],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068648945,0.000114354676,0.00020244184,0.00014337424,0.0000938948,0.00002416558,0.00030731538,0.00007099678,0.00003016824],"category_scores_gemma":[0.00030859094,0.000095017975,0.00009101387,0.00024807447,0.0005514973,0.000040393974,0.000063627325,0.00012896111,5.4189127e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025894793,0.000095295385,0.00056638266,0.000022140848,0.0000230292,0.000021233263,0.00019518757,0.00005881505,0.9970561,0.000014201329,2.50805e-7,0.0016884045],"study_design_scores_gemma":[0.00040867046,0.00026211486,0.0018908264,0.00006669705,0.000020049787,0.0004728502,0.00013799337,0.0021694305,0.9941464,0.00012684536,0.00019375175,0.00010436579],"about_ca_topic_score_codex":0.00009590663,"about_ca_topic_score_gemma":0.000003993731,"teacher_disagreement_score":0.010456929,"about_ca_system_score_codex":0.000015456786,"about_ca_system_score_gemma":0.00017874404,"threshold_uncertainty_score":0.38747206},"labels":[],"label_agreement":null},{"id":"W2036373102","doi":"10.1016/s0021-9673(02)02057-5","title":"Current and prospective applications of metal ion–protein binding","year":2003,"lang":"en","type":"review","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":453,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Chemistry; Affinity chromatography; Chromatography; Protein purification; Metal; Metal ions in aqueous solution; Matrix (chemical analysis); Folding (DSP implementation); Separation method; Combinatorial chemistry; Biochemistry; Organic chemistry; Enzyme","score_opus":0.018517990541862116,"score_gpt":0.3109947104686501,"score_spread":0.29247671992678803,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036373102","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009148942,0.9966055,0.0014209618,0.000004176095,0.000063297295,0.0007886815,0.000051689065,0.000002493635,0.00014830951],"genre_scores_gemma":[0.0027974914,0.9960784,0.0008620916,0.0000019954794,0.00009456888,0.0001155698,0.000020275917,0.000017026481,0.000012608124],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986011,0.00015561009,0.000734379,0.0002179943,0.000174949,0.00011601465],"domain_scores_gemma":[0.9982453,0.000013161255,0.001155202,0.00027645545,0.0002193372,0.000090531095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000443917,0.00020188026,0.00073328277,0.00025977154,0.000049231916,0.000015846592,0.00020059147,0.00017169207,0.0000088326],"category_scores_gemma":[0.000047847756,0.0001565005,0.00062937784,0.000356627,0.00014811018,0.000005334095,0.00003656294,0.00023477408,8.3723864e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027394137,0.00054756814,0.00028918628,0.011492608,0.0010528888,0.0000018582459,0.00003632621,1.0687238e-7,0.0051318994,0.0018405647,0.00013371077,0.9794459],"study_design_scores_gemma":[0.00021019239,0.00015033441,0.00003490183,0.0012226308,0.0003017543,0.00011172974,0.000013142948,5.9072953e-8,0.0020888136,0.0002716812,0.9954388,0.00015593346],"about_ca_topic_score_codex":4.389991e-7,"about_ca_topic_score_gemma":4.2827693e-7,"teacher_disagreement_score":0.9953051,"about_ca_system_score_codex":0.000014443818,"about_ca_system_score_gemma":0.0002332187,"threshold_uncertainty_score":0.6381905},"labels":[],"label_agreement":null},{"id":"W2036623928","doi":"10.1016/j.ijpharm.2005.10.005","title":"Preparation and characterization of dehydration–rehydration vesicles loaded with aminoglycoside and macrolide antibiotics","year":2005,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Laurentian University","funders":"","keywords":"Aminoglycoside; Antibiotics; Dehydration; Chemistry; Macrolide Antibiotics; Vesicle; Microbiology; Biochemistry; Biology; Erythromycin","score_opus":0.013437154255010936,"score_gpt":0.3176563124267036,"score_spread":0.30421915817169265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036623928","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98363495,0.00031641303,0.015025714,0.00077322725,0.00007583133,0.00010547641,0.000016748038,0.0000027056547,0.00004895497],"genre_scores_gemma":[0.99629635,0.000729093,0.0025051837,0.00017451672,0.00021250946,5.5862836e-7,0.00004439904,0.0000066914495,0.000030713763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992697,0.000044683024,0.00032792444,0.00010288579,0.0001963216,0.000058436908],"domain_scores_gemma":[0.9990594,0.000011924538,0.00036558122,0.000067178844,0.00044657072,0.000049343937],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020165856,0.00007559825,0.000089067165,0.00006447579,0.000027690972,0.000034451437,0.000087989334,0.000049991635,0.000006216106],"category_scores_gemma":[0.00004590557,0.000066965324,0.000021830165,0.000035377907,0.00007645937,0.00004193306,0.000025811643,0.00006203986,3.763459e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037351417,0.00006984077,0.008083081,0.000011052443,0.00006666909,0.000001038062,0.00020143778,0.00013571003,0.97797686,0.00014822169,0.000005152756,0.012927411],"study_design_scores_gemma":[0.00076160405,0.00014759743,0.01864499,0.000018977049,0.000028786524,0.00009019954,0.000028712937,0.0020070542,0.9719875,0.0000410084,0.006175316,0.000068284164],"about_ca_topic_score_codex":0.0000010658028,"about_ca_topic_score_gemma":0.0000061950236,"teacher_disagreement_score":0.0128591275,"about_ca_system_score_codex":0.000017117009,"about_ca_system_score_gemma":0.000055342618,"threshold_uncertainty_score":0.27307665},"labels":[],"label_agreement":null},{"id":"W2036701515","doi":"10.1016/j.biologicals.2009.12.005","title":"Approach to the profiling and characterization of influenza vaccine constituents by the combined use of size-exclusion chromatography, gel electrophoresis and mass spectrometry","year":2010,"lang":"en","type":"article","venue":"Biologicals","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Chromatography; Size-exclusion chromatography; Mass spectrometry; Influenza vaccine; Chemistry; Biology; Virology","score_opus":0.013319332817672357,"score_gpt":0.24085189056345518,"score_spread":0.22753255774578282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036701515","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99763006,0.00036546073,0.001115833,0.00020824959,0.000019471678,0.0005515788,0.00007189634,0.000005264214,0.00003220669],"genre_scores_gemma":[0.99778295,0.00028319156,0.0015999316,0.00020912912,0.00001615531,0.000032597247,0.000063757136,0.0000035414673,0.000008748521],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993144,0.000098672135,0.00020963377,0.00021322988,0.00006253188,0.00010150192],"domain_scores_gemma":[0.99945897,0.000048774138,0.00012220038,0.00026284525,0.000069565904,0.000037629987],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003188683,0.00008838987,0.00013673038,0.00001857182,0.00007501889,0.000014594946,0.00012820128,0.00011597074,0.000005212686],"category_scores_gemma":[0.00037876976,0.000045527726,0.00003084293,0.00012910715,0.00015986458,0.0000034903805,0.00009065898,0.00007417808,1.6485893e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011534857,0.000060919385,0.04876869,0.000012073791,0.000016422742,1.8770933e-8,0.000010214452,1.5370031e-7,0.950382,0.0003128701,0.000018436804,0.0003028663],"study_design_scores_gemma":[0.00023159538,0.0001996456,0.25097302,0.000002525377,0.000008608704,0.000002213874,0.000011243461,0.000029080977,0.74613684,0.00006127326,0.0022829648,0.000060962593],"about_ca_topic_score_codex":0.000006716745,"about_ca_topic_score_gemma":0.0000010207448,"teacher_disagreement_score":0.2042451,"about_ca_system_score_codex":0.0000016945805,"about_ca_system_score_gemma":0.000011620001,"threshold_uncertainty_score":0.18565668},"labels":[],"label_agreement":null},{"id":"W2037333379","doi":"10.1016/j.jconrel.2004.10.020","title":"Sustained interferon-γ delivery from a photocrosslinked biodegradable elastomer","year":2004,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Queen's University","funders":"","keywords":"Bovine serum albumin; Elastomer; Drug delivery; Chemistry; Delivery system; Biomedical engineering; Chromatography; Medicine; Organic chemistry","score_opus":0.006379782424324684,"score_gpt":0.2331628532781167,"score_spread":0.226783070853792,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037333379","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98331773,0.0064058756,0.008385743,0.00090106204,0.0002054106,0.00037494014,0.00001985679,0.000007483059,0.00038189508],"genre_scores_gemma":[0.99768096,0.0002811466,0.0010134982,0.0003700725,0.00025123692,0.000016218473,0.000013628417,0.000013521934,0.00035971342],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876577,0.0001000006,0.00057091063,0.00017886245,0.00019225868,0.00019217622],"domain_scores_gemma":[0.99866456,0.00003102174,0.00039623457,0.00028499638,0.00044734817,0.00017581697],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032613575,0.00014693617,0.00036713178,0.00007167788,0.000068849906,0.00004026475,0.0002327629,0.00013655225,0.00007295046],"category_scores_gemma":[0.00046899062,0.000110538276,0.00033469405,0.000075170916,0.00007966786,0.000010593275,0.000048792117,0.00019550124,0.00001245591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.028102286,0.00062825915,0.00030925067,0.000013889436,0.00052304973,0.00006326707,0.00013447634,0.00041433924,0.96323645,0.000120879005,0.000753489,0.0057003335],"study_design_scores_gemma":[0.16247295,0.004738669,0.0017901618,0.00016856004,0.00045446074,0.00017248612,0.0013991491,0.00048990495,0.73342323,0.006882374,0.087030634,0.0009774003],"about_ca_topic_score_codex":0.000039104812,"about_ca_topic_score_gemma":0.000016279297,"teacher_disagreement_score":0.22981323,"about_ca_system_score_codex":0.000059658174,"about_ca_system_score_gemma":0.0004181229,"threshold_uncertainty_score":0.450762},"labels":[],"label_agreement":null},{"id":"W2037392667","doi":"10.1016/s0301-4622(01)00236-8","title":"Modeling of orthokinetic flocculation of Saccharomyces cerevisiae","year":2001,"lang":"en","type":"article","venue":"Biophysical Chemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Flocculation; Laminar flow; Saccharomyces cerevisiae; DLVO theory; Thermodynamics; Shear rate; Yeast; Chromatography; Rheology; Biochemistry; Physical chemistry; Colloid; Physics; Organic chemistry","score_opus":0.012745477079180369,"score_gpt":0.2469641599999304,"score_spread":0.23421868292075004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037392667","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952105,0.00032192387,0.002985989,0.000041840194,0.000012120938,0.000074534,0.0000137383195,0.0000070268093,0.0013323142],"genre_scores_gemma":[0.9992018,0.00006733528,0.00045000773,0.000007979558,0.000096846874,0.0000075119697,0.0000716315,0.0000072500366,0.0000896414],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993322,0.000014898841,0.00023904855,0.00020489955,0.00011384129,0.0000951127],"domain_scores_gemma":[0.99943596,0.0000048824586,0.00007913109,0.00032689454,0.00010970717,0.000043417982],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006236929,0.00008731454,0.00013773571,0.0000072606217,0.000016371321,0.0000030901222,0.00012568856,0.00009534175,0.000047774174],"category_scores_gemma":[0.00006380501,0.000083838175,0.000098664896,0.000085954096,0.00006870267,0.0000024155647,0.000039992112,0.000043683016,0.0000016519243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047814417,0.000098323966,0.0010701014,0.000087375294,0.000012566194,1.8012813e-7,0.000007369747,0.000516314,0.9971324,0.000041195377,0.0000064336236,0.0009798827],"study_design_scores_gemma":[0.00020492435,0.0000325078,0.0015222129,0.000015091396,0.000011281395,0.0000019448225,0.000018416684,0.009818977,0.98757863,0.00012333874,0.0005747225,0.000097942946],"about_ca_topic_score_codex":0.0000093609615,"about_ca_topic_score_gemma":3.9119115e-7,"teacher_disagreement_score":0.009553803,"about_ca_system_score_codex":0.000005148489,"about_ca_system_score_gemma":0.00003116401,"threshold_uncertainty_score":0.34188217},"labels":[],"label_agreement":null},{"id":"W2037714516","doi":"10.1016/j.jim.2010.05.006","title":"Membrane bioreactor separator system for integrated IgG fragmentation and Fab purification","year":2010,"lang":"en","type":"article","venue":"Journal of Immunological Methods","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Shell Canada","keywords":"Bioreactor; Chromatography; Chemistry; Membrane; Membrane bioreactor; Microporous material; Papain; Separator (oil production); Biochemistry; Organic chemistry","score_opus":0.020562934577753773,"score_gpt":0.353096285735845,"score_spread":0.33253335115809124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037714516","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85653526,0.0011708866,0.14133517,0.0002294774,0.0003830301,0.00024826283,0.000013432028,0.000008886756,0.000075581745],"genre_scores_gemma":[0.7230398,0.0001203307,0.27663502,0.000037346326,0.00009035067,0.000024569166,0.000017877564,0.000006043178,0.000028624858],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989278,0.00030829723,0.00041489914,0.00016567721,0.000074974494,0.00010837548],"domain_scores_gemma":[0.99894446,0.00009816294,0.00034846642,0.00019227376,0.00035457223,0.00006203726],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016521972,0.00010207446,0.00019488369,0.000046867066,0.00006600844,0.000032943743,0.00015433588,0.00023384864,0.000011620231],"category_scores_gemma":[0.0011861818,0.000070322596,0.00009600216,0.00007261707,0.00010278142,0.000010035346,0.00002235375,0.00021501374,7.938944e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029662787,0.000055528566,0.00012407363,0.00001911956,0.000038501425,2.9863887e-7,0.00002008012,5.5363125e-7,0.93500394,0.0005547922,0.000016434748,0.06387006],"study_design_scores_gemma":[0.0006566871,0.0004885618,0.008072202,0.000009797073,0.000026091437,0.00004427999,0.0002693724,0.00006352855,0.9460817,0.00014701458,0.04404614,0.00009462463],"about_ca_topic_score_codex":0.0000021451954,"about_ca_topic_score_gemma":5.9478884e-7,"teacher_disagreement_score":0.13529986,"about_ca_system_score_codex":0.000019344685,"about_ca_system_score_gemma":0.00006190918,"threshold_uncertainty_score":0.2867672},"labels":[],"label_agreement":null},{"id":"W2039455049","doi":"10.1002/cjce.20401","title":"Optimal design of a four‐zone simulated moving bed process for separation of homoharringtonine and harringtonine","year":2010,"lang":"en","type":"article","venue":"The Canadian Journal of Chemical Engineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Simulated moving bed; Homoharringtonine; Chromatography; Particle size; Mass transfer; Ammonium formate; Throughput; Pressure drop; Adsorption; Materials science; Extraction (chemistry); Chemistry; Process engineering; Analytical Chemistry (journal); Computer science; Acetonitrile; Mechanics; Engineering","score_opus":0.011756926231105835,"score_gpt":0.24099919700320777,"score_spread":0.22924227077210194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039455049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9658871,0.00022179168,0.033604514,0.00009744765,0.000037056794,0.00013789095,0.000008850565,0.0000017018127,0.0000036041095],"genre_scores_gemma":[0.994808,0.0000014889647,0.005102818,0.00000767634,0.000058685724,0.0000032333933,0.0000037479326,0.000009566079,0.000004765164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999493,0.000007976327,0.00025040755,0.00007208395,0.00006255534,0.00011399123],"domain_scores_gemma":[0.9993637,0.00003279125,0.00013496594,0.000110882684,0.00022998595,0.00012767644],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033981737,0.000070204704,0.00013193864,0.00004164686,0.000025481058,0.000008808903,0.00013497844,0.00007945737,0.0000049012992],"category_scores_gemma":[0.00053036545,0.000058223515,0.00004284727,0.000056129662,0.00006593097,0.0000063306475,0.0000065680665,0.00012759928,2.2747322e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051229774,0.0000052851633,0.000117767224,0.000041870193,0.000025469053,3.503995e-7,0.00008459156,0.07123729,0.9282284,0.00003637348,0.000002947858,0.00016843791],"study_design_scores_gemma":[0.00035711424,0.00007402142,0.00012639367,0.000021168282,0.000016954398,0.00002389907,0.000006898991,0.051498294,0.947705,0.000016799982,0.00009457374,0.00005893041],"about_ca_topic_score_codex":0.00005329091,"about_ca_topic_score_gemma":0.00003148199,"teacher_disagreement_score":0.028920876,"about_ca_system_score_codex":0.000009985543,"about_ca_system_score_gemma":0.0002067464,"threshold_uncertainty_score":0.2374286},"labels":[],"label_agreement":null},{"id":"W2040377616","doi":"10.1246/cl.2012.1380","title":"The Thermally Induced Aggregation of Immunoglobulin G in Solution is Prevented by Amphipols","year":2012,"lang":"en","type":"article","venue":"Chemistry Letters","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Antibody; Chemical engineering; Immunology","score_opus":0.008745864266456753,"score_gpt":0.23608634460104969,"score_spread":0.22734048033459292,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040377616","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99620104,0.0015535185,0.00021362043,0.0016455785,0.000035971487,0.00014278675,0.000012052256,0.0000050935428,0.00019035189],"genre_scores_gemma":[0.999368,0.00006704707,0.000045348017,0.00026063787,0.000053313834,0.000035254936,0.000084535015,0.0000067517426,0.00007909389],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993452,0.000046478686,0.00020386628,0.00013533799,0.000090429734,0.00017867993],"domain_scores_gemma":[0.99949116,0.0000104374985,0.00011418572,0.0003205305,0.0000298286,0.00003389125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028434713,0.00008260628,0.00006657855,0.000005120141,0.000047339152,0.000007924043,0.00016337147,0.000096147574,0.000021357253],"category_scores_gemma":[0.000069618494,0.00006990091,0.000047571837,0.00006008069,0.000074847805,0.000005447106,0.000034833207,0.000078769874,0.000002456658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036580663,0.000050406,0.003797136,0.000015658086,0.000012276521,3.336096e-8,0.00006630134,7.637463e-7,0.9931175,0.0000018836329,0.00074744574,0.0021540222],"study_design_scores_gemma":[0.00023623541,0.0000051885177,0.007658376,0.000008394125,0.0000032082849,9.704272e-7,0.000028174134,0.00000986512,0.98644507,0.0000039947167,0.0055252686,0.00007522955],"about_ca_topic_score_codex":0.00001385516,"about_ca_topic_score_gemma":9.1587725e-7,"teacher_disagreement_score":0.0066723973,"about_ca_system_score_codex":0.000027899616,"about_ca_system_score_gemma":0.000022193763,"threshold_uncertainty_score":0.28504762},"labels":[],"label_agreement":null},{"id":"W2041424999","doi":"10.1016/j.chroma.2007.05.107","title":"A novel two-zone protein uptake model for affinity chromatography and its application to the description of elution band profiles of proteins fused to a family 9 cellulose binding module affinity tag","year":2007,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Chemistry; Elution; Chromatography; Affinity chromatography; Stationary phase; Diffusion; Phase (matter); Lysis; Cellulose; Sorption; Particle (ecology); Porosity; High-performance liquid chromatography; Analytical Chemistry (journal); Adsorption; Biochemistry; Organic chemistry","score_opus":0.02467370682154915,"score_gpt":0.2622183429261426,"score_spread":0.23754463610459345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041424999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6189515,0.00037354644,0.37849078,0.000103539554,0.000022764414,0.0019426561,0.000089191606,0.000006027703,0.000019985891],"genre_scores_gemma":[0.9718963,0.000026346781,0.027681885,0.00004367308,0.00006832497,0.00023680297,0.0000193697,0.000018726369,0.000008586351],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982444,0.00006519035,0.00083293533,0.00028991138,0.00032184526,0.0002457327],"domain_scores_gemma":[0.9980198,0.000022269198,0.00076444924,0.00033835106,0.00068295177,0.00017213577],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017929701,0.00019460262,0.00032354798,0.00036929207,0.00011800623,0.000023490935,0.00027607023,0.0001474098,0.0000011162571],"category_scores_gemma":[0.00018244401,0.00015634712,0.00026711868,0.00062509696,0.00009255149,0.000029302726,0.000048771915,0.0001248275,3.0509943e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000790892,0.00045305755,0.0007062711,0.00019285126,0.00007721336,1.6445301e-7,0.00030374786,0.00031935176,0.9955286,0.00040522707,0.000033761688,0.0011888843],"study_design_scores_gemma":[0.0013859307,0.000808544,0.021224797,0.000109525135,0.00004884776,0.000011782111,0.0001815212,0.002376109,0.9730676,0.00020544934,0.00040374752,0.00017617278],"about_ca_topic_score_codex":0.000020181573,"about_ca_topic_score_gemma":0.000069743335,"teacher_disagreement_score":0.3529448,"about_ca_system_score_codex":0.000019794797,"about_ca_system_score_gemma":0.0001233237,"threshold_uncertainty_score":0.637565},"labels":[],"label_agreement":null},{"id":"W2041691792","doi":"10.1021/la902395v","title":"Method for Studying Immunoglobulin G Binding on Hydrophobic Surfaces","year":2009,"lang":"en","type":"article","venue":"Langmuir","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Membrane; Papain; Chromatography; Sodium dodecyl sulfate; Microporous material; Gel electrophoresis; Enzyme; Biochemistry; Organic chemistry","score_opus":0.023174658527580733,"score_gpt":0.32057325569647305,"score_spread":0.29739859716889233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041691792","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885542,0.0007092554,0.007373211,0.00077098777,0.00006175291,0.00036460182,0.000028022607,0.000029610392,0.0021083737],"genre_scores_gemma":[0.9899178,0.000017731449,0.008820211,0.00036585802,0.00007660598,0.000025123027,0.000075752934,0.000007485134,0.00069343514],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99939847,0.000050763672,0.00011389181,0.00022999494,0.00006286457,0.00014400248],"domain_scores_gemma":[0.9996695,0.000015978896,0.00004236526,0.00021338977,0.00003156867,0.000027190752],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029143112,0.00008398572,0.0000908304,0.000019523502,0.000100802376,0.000017529137,0.0001227895,0.00007137714,0.0000102278755],"category_scores_gemma":[0.000035554967,0.00007405141,0.0000621752,0.000052180083,0.000011724891,0.0000016102432,0.00001479217,0.000043739223,0.000013442855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011063616,0.00008725982,0.00030442287,0.0000088552615,0.000016713631,4.5392318e-7,0.00006836942,0.00002531215,0.97212875,0.0005264321,0.0005220406,0.026200755],"study_design_scores_gemma":[0.0009801501,0.0007337362,0.028682452,0.000011174489,0.000014912066,0.0000037866316,0.00014242632,0.0002893091,0.7911184,0.0006559278,0.1770661,0.00030161018],"about_ca_topic_score_codex":0.000004366548,"about_ca_topic_score_gemma":0.0000019569693,"teacher_disagreement_score":0.18101034,"about_ca_system_score_codex":0.00001144567,"about_ca_system_score_gemma":0.000013484607,"threshold_uncertainty_score":0.3019729},"labels":[],"label_agreement":null},{"id":"W2045326683","doi":"10.1002/jps.24117","title":"Advanced Kinetic Analysis as a Tool for Formulation Development and Prediction of Vaccine Stability","year":2014,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Stability (learning theory); Kinetic energy; Autocatalysis; Degradation (telecommunications); Biological system; Residual; Adjuvant; Mathematics; Computer science; Applied mathematics; Biochemical engineering; Kinetics; Algorithm; Physics; Engineering; Medicine; Biology; Machine learning","score_opus":0.035931114184990995,"score_gpt":0.35136074610684503,"score_spread":0.315429631921854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2045326683","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94734097,0.00027840497,0.05193732,0.00021557708,0.00003641369,0.00012463778,0.000003481699,0.0000013250556,0.00006185112],"genre_scores_gemma":[0.9911179,0.000038618775,0.008755905,0.00004272263,0.000030995692,0.000004433834,0.0000030440992,0.000001220321,0.0000051740208],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992504,0.00005202572,0.000330852,0.000122051606,0.0001605751,0.00008408092],"domain_scores_gemma":[0.9994791,0.00004697797,0.00016922386,0.00006023889,0.00018370205,0.000060756855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014265408,0.00004740882,0.00011672497,0.000049755592,0.00006145348,0.000010243723,0.00008446077,0.000031484233,0.000017149723],"category_scores_gemma":[0.0004822855,0.000034547018,0.000059585105,0.00016057688,0.000061576,0.000012094468,0.000018871353,0.000033154007,9.977275e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047880434,0.00016308927,0.09371971,0.00006647657,0.000118664866,5.9512573e-8,0.0001143848,0.00044975226,0.7887428,0.00082163146,0.000009050982,0.11531559],"study_design_scores_gemma":[0.00091757986,0.00068519794,0.17406698,0.0000069556695,0.00012085855,0.0000039435017,0.000045549248,0.009561865,0.7964021,0.0006722315,0.017449696,0.000067045505],"about_ca_topic_score_codex":6.860932e-7,"about_ca_topic_score_gemma":0.0000024808915,"teacher_disagreement_score":0.11524854,"about_ca_system_score_codex":0.000010291837,"about_ca_system_score_gemma":0.000059475144,"threshold_uncertainty_score":0.14087865},"labels":[],"label_agreement":null},{"id":"W2045780173","doi":"10.1016/j.jchromb.2014.06.037","title":"Simulated moving bed purification of flaxseed oil orbitides: Unprecedented separation of cyclolinopeptides C and E","year":2014,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Ministry of Agriculture - Saskatchewan; University of Saskatchewan; Genome Canada","keywords":"Chemistry; Simulated moving bed; Chromatography; Yield (engineering); Adsorption; Organic chemistry","score_opus":0.006700052975951213,"score_gpt":0.25682191667723975,"score_spread":0.2501218637012885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2045780173","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99669015,0.0010106016,0.0018491616,0.000065286375,0.000039332335,0.000064614425,0.0000053629415,0.00000427741,0.00027120055],"genre_scores_gemma":[0.99811584,0.0003821097,0.0014025744,0.000021350996,0.000041597414,0.0000014396267,0.00001639055,0.000007909401,0.000010774372],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888957,0.00012978578,0.00060667924,0.00012367056,0.0001648017,0.00008546764],"domain_scores_gemma":[0.99853826,0.000032884105,0.0007203809,0.00021127811,0.0004355548,0.00006162756],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005265066,0.000093674294,0.00022630944,0.00014071845,0.00003257816,0.000011097599,0.00012099273,0.0001020864,0.0000061979517],"category_scores_gemma":[0.00022027332,0.00008332722,0.0001360213,0.00017463998,0.00012226695,0.0000140202155,0.000017557919,0.0000648357,1.999263e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013738615,0.00009332028,0.017515797,0.00009250967,0.00007574423,1.4741875e-7,0.00010196417,0.00014047064,0.97946054,0.0001178817,0.00003027975,0.0022339525],"study_design_scores_gemma":[0.0009649901,0.00036891355,0.07017535,0.00008766452,0.00004499098,0.000017438782,0.00009341522,0.0006457388,0.9258094,0.00023381627,0.0014532149,0.000105060564],"about_ca_topic_score_codex":0.000013111211,"about_ca_topic_score_gemma":0.0000062318945,"teacher_disagreement_score":0.05365114,"about_ca_system_score_codex":0.000004680621,"about_ca_system_score_gemma":0.00004105043,"threshold_uncertainty_score":0.33979854},"labels":[],"label_agreement":null},{"id":"W2046945489","doi":"10.1021/bi800847a","title":"Structural Investigation of a Phosphorylation-Catalyzed, Isoaspartate-Free, Protein Succinimide: Crystallographic Structure of Post-Succinimide His15Asp Histidine-Containing Protein","year":2008,"lang":"en","type":"article","venue":"Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"National Center for Research Resources; U.S. Department of Energy","keywords":"Succinimide; Succinimides; Chemistry; Phosphorylation; Histidine; Deamidation; Stereochemistry; Hydrolysis; Protein structure; Biochemistry; Amino acid; Organic chemistry; Enzyme","score_opus":0.011158119862634075,"score_gpt":0.21565199326161896,"score_spread":0.2044938733989849,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046945489","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969422,0.0014607572,0.00008891941,0.00015544344,0.000044328543,0.0008270613,0.00035563702,0.00003426307,0.000091395406],"genre_scores_gemma":[0.99602586,0.000020791882,0.002712786,0.000033842683,0.00008659305,0.00007150543,0.000813005,0.00003555836,0.00020003006],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977795,0.00009170844,0.0008097565,0.0006420652,0.00036237808,0.00031463115],"domain_scores_gemma":[0.99743515,0.000017933578,0.0006679486,0.0011101833,0.0005990225,0.00016975822],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019461253,0.000344957,0.00038908698,0.000084453546,0.00014577262,0.000011205561,0.0005296114,0.0003991052,0.0000854895],"category_scores_gemma":[0.00071479,0.00034716292,0.00020139446,0.00030253633,0.0005554389,0.000019064668,0.00015514484,0.00020703588,7.9495527e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046017836,0.000033811237,0.020549456,0.00029294143,0.00006484207,0.0000022932043,0.00015348385,0.000021120957,0.9781582,0.00007451479,0.0000609205,0.00012826775],"study_design_scores_gemma":[0.0010374852,0.00018428017,0.023662563,0.00006790949,0.00002248932,0.000026217775,0.000109085486,0.00006648894,0.9739997,0.00039391246,0.000093336894,0.00033655053],"about_ca_topic_score_codex":0.00017791601,"about_ca_topic_score_gemma":0.000038763985,"teacher_disagreement_score":0.004158491,"about_ca_system_score_codex":0.000043792366,"about_ca_system_score_gemma":0.00047315576,"threshold_uncertainty_score":0.999898},"labels":[],"label_agreement":null},{"id":"W2049754685","doi":"10.1016/j.ab.2003.12.015","title":"Use of 2,3-diaminonapthalene for studying denitrosation activity of protein disulfide isomerase","year":2004,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Windsor","funders":"","keywords":"Protein disulfide-isomerase; Chemistry; Disulfide bond; Biochemistry; Isomerase; Enzyme","score_opus":0.03978675679395987,"score_gpt":0.29034106838748946,"score_spread":0.2505543115935296,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049754685","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9857373,0.00018982217,0.013344532,0.00016615185,0.000010555252,0.00037441475,0.00012267557,0.0000065381905,0.00004795825],"genre_scores_gemma":[0.9968204,0.000015848624,0.0028076598,0.000019295492,0.000040862993,0.000058522935,0.00009610692,0.000010192953,0.00013111225],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907094,0.000023253613,0.00029047986,0.0003144953,0.00014481583,0.00015599644],"domain_scores_gemma":[0.999102,0.000030687068,0.00015598777,0.00042385494,0.00020772738,0.00007973503],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017249153,0.00012272321,0.00018921409,0.000023323992,0.000035997902,0.000008956912,0.0001276227,0.0001522804,0.00000884508],"category_scores_gemma":[0.0006582915,0.00012076148,0.00015238216,0.00010235018,0.00017650596,0.000007254272,0.000053241016,0.00006144061,6.1907406e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022326234,0.0003460255,0.0014482944,0.00014113635,0.000053144297,3.071749e-7,0.000008777628,0.000026751764,0.99557406,0.00021128135,0.000007854079,0.001959105],"study_design_scores_gemma":[0.0005465939,0.00013822384,0.002735683,0.00002609278,0.000029648725,0.0000013103916,0.000020010511,0.000100052406,0.99584013,0.0002741179,0.00016733258,0.000120776975],"about_ca_topic_score_codex":0.000030461637,"about_ca_topic_score_gemma":0.000004596184,"teacher_disagreement_score":0.011083046,"about_ca_system_score_codex":0.000027232789,"about_ca_system_score_gemma":0.00013700554,"threshold_uncertainty_score":0.492451},"labels":[],"label_agreement":null},{"id":"W2051351267","doi":"10.1016/j.chroma.2006.08.042","title":"One-step purification of a recombinant protein from a whole cell extract by reversed-phase high-performance liquid chromatography","year":2006,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institutes of Health; University of Alberta","keywords":"Chemistry; Chromatography; High-performance liquid chromatography; Recombinant DNA; Reversed-phase chromatography; Hydrophilic interaction chromatography; Phase (matter); Biochemistry; Organic chemistry","score_opus":0.006676896268346462,"score_gpt":0.22324994025378095,"score_spread":0.21657304398543448,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051351267","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99134165,0.0045905747,0.002928209,0.00018960187,0.00012255205,0.00045409342,0.000109743334,0.0000133021285,0.00025027696],"genre_scores_gemma":[0.99330705,0.00037477375,0.005852703,0.0000337813,0.000118681535,0.000037299702,0.00019790752,0.000025873593,0.000051926865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978576,0.00015755105,0.0010282173,0.0003197897,0.00038532165,0.00025157855],"domain_scores_gemma":[0.9977199,0.000015492136,0.0012527012,0.0005566145,0.0003331029,0.0001222313],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050693174,0.00022561253,0.00040036265,0.0002268662,0.00008703819,0.000031062158,0.0003897851,0.00022869653,0.00003766671],"category_scores_gemma":[0.000030416615,0.0002173868,0.0003701689,0.00041820633,0.00017816773,0.00003828069,0.000030993524,0.00020635585,0.000003627772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069299294,0.001803968,0.001101782,0.00010197903,0.000086454325,0.0000022480942,0.000024878595,0.0000061719797,0.9919643,0.000036974663,0.002765541,0.0014127563],"study_design_scores_gemma":[0.002733699,0.0018703089,0.008928939,0.00012342389,0.000059728573,0.000011815328,0.000039083752,0.00003203319,0.9541308,0.00019487238,0.031628292,0.00024698538],"about_ca_topic_score_codex":0.00009481231,"about_ca_topic_score_gemma":0.0000069968023,"teacher_disagreement_score":0.037833434,"about_ca_system_score_codex":0.000017433995,"about_ca_system_score_gemma":0.000121170786,"threshold_uncertainty_score":0.88647765},"labels":[],"label_agreement":null},{"id":"W2054999078","doi":"10.1016/j.memsci.2009.08.043","title":"Chromatographic separation of proteins using hydrophobic membrane shielded with an environment-responsive hydrogel","year":2009,"lang":"en","type":"article","venue":"Journal of Membrane Science","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Membrane; Polyvinylidene fluoride; Microporous material; Chromatography; Chemistry; Chemical engineering; Salt (chemistry); Polymer chemistry; Hydrophobic effect; Organic chemistry; Biochemistry","score_opus":0.012188408707319773,"score_gpt":0.276668597140071,"score_spread":0.26448018843275123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054999078","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970281,0.00024914095,0.002195492,0.00013740562,0.000029903498,0.00023805189,0.0000027787755,0.000003099407,0.00011600792],"genre_scores_gemma":[0.9942729,0.00007969264,0.0055135014,0.00006645909,0.000044026456,0.0000017446824,0.000002128615,0.00000532357,0.000014249883],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99861914,0.00008131541,0.000373803,0.000245066,0.000498438,0.0001822278],"domain_scores_gemma":[0.9988325,0.0000074770915,0.00045662344,0.0003639214,0.0001924495,0.00014701772],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010443339,0.00011548335,0.00018517749,0.00016576247,0.00012400522,0.000025393729,0.000374216,0.00006709431,0.000017088956],"category_scores_gemma":[0.00008703315,0.00008918833,0.00007102463,0.0003399275,0.00044436654,0.000053655825,0.000020673688,0.000107006126,6.5800646e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037075303,0.00015928288,0.00020712393,0.000009669301,0.000009217823,0.0000039119022,0.00009522569,0.0011115108,0.997663,0.000058009606,4.7139883e-7,0.0003117996],"study_design_scores_gemma":[0.0005810441,0.0016812986,0.0038811807,0.000025976564,0.000018270408,0.00016751088,0.000068264,0.0009751069,0.99223703,0.000091517424,0.00016174294,0.00011105167],"about_ca_topic_score_codex":0.0000042768447,"about_ca_topic_score_gemma":0.000002739672,"teacher_disagreement_score":0.005425988,"about_ca_system_score_codex":0.000024152521,"about_ca_system_score_gemma":0.00037146083,"threshold_uncertainty_score":0.36369944},"labels":[],"label_agreement":null},{"id":"W2056086231","doi":"10.1002/bit.21680","title":"Paper‐PEG‐based membranes for hydrophobic interaction chromatography: Purification of monoclonal antibody","year":2007,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Membrane; PEG ratio; Chromatography; Monoclonal antibody; Chemistry; Polymer; Synthetic membrane; Chemical engineering; Antibody; Biochemistry; Organic chemistry; Biology","score_opus":0.008871678040510242,"score_gpt":0.2602947676255339,"score_spread":0.25142308958502363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056086231","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88245165,0.0021676908,0.11463709,0.0003222754,0.00008768821,0.0002424745,0.000014249272,0.00004812412,0.000028730921],"genre_scores_gemma":[0.99392134,0.00027398314,0.0056147194,0.000026324406,0.00003389439,0.000020478887,0.000095253185,0.0000090125795,0.0000049953856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993894,0.000007311163,0.00019701697,0.00022577992,0.000039629394,0.00014085248],"domain_scores_gemma":[0.9996312,0.000015614592,0.00006916719,0.00021279347,0.00004209514,0.000029128309],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022429395,0.00009889613,0.00010464283,0.00012682358,0.00004584394,0.000004849722,0.000087870656,0.0002895458,0.0000031251293],"category_scores_gemma":[0.00003890755,0.00009678053,0.000056149136,0.00011838323,0.000109173016,0.0000053010813,0.000018532948,0.000066220025,3.7620012e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000862478,0.00003885876,0.00070521916,0.00009841635,0.000024283807,2.667536e-7,0.0000049620444,0.00003112287,0.9949138,0.00059044047,0.0000025706263,0.003503791],"study_design_scores_gemma":[0.00029100582,0.00015626803,0.0037251913,0.00001102556,0.000010763649,0.000010065201,0.000030733732,0.0013550567,0.98237336,0.000051297582,0.011880361,0.000104862505],"about_ca_topic_score_codex":0.000006191117,"about_ca_topic_score_gemma":0.000004892185,"teacher_disagreement_score":0.11146966,"about_ca_system_score_codex":0.000005965927,"about_ca_system_score_gemma":0.000013436969,"threshold_uncertainty_score":0.39465955},"labels":[],"label_agreement":null},{"id":"W2058471179","doi":"10.1002/cjce.5450820319","title":"Multiobjective Optimization of Simulated Moving Bed Reactor and its Modification — Varicol Process","year":2004,"lang":"en","type":"article","venue":"The Canadian Journal of Chemical Engineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Sorting; Multi-objective optimization; Process (computing); Genetic algorithm; Computer science; Simulated moving bed; Mathematical optimization; Process engineering; Engineering; Chemistry; Algorithm; Mathematics; Organic chemistry","score_opus":0.008189458132066561,"score_gpt":0.21938117088229592,"score_spread":0.21119171275022935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058471179","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866634,0.0004225801,0.012600185,0.00015772194,0.000023783261,0.000111155074,0.000004990336,0.0000023257162,0.000013872159],"genre_scores_gemma":[0.9992271,0.0000048833813,0.0007051765,0.000012848531,0.00003423515,0.0000018667095,0.0000056571967,0.0000068448685,0.0000013686249],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996113,0.00000881878,0.0001710224,0.00006709591,0.000059696296,0.00008205943],"domain_scores_gemma":[0.999488,0.000009862693,0.00009709832,0.00007695558,0.0002192288,0.00010886346],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013611514,0.000055321787,0.000074711046,0.00003613195,0.000022802094,0.000010041417,0.00009226425,0.00006766957,0.0000023133748],"category_scores_gemma":[0.00044415888,0.000046146015,0.000024833971,0.0000768353,0.000025474266,0.000007743692,0.00000509269,0.00009053468,6.719777e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011800987,0.00000609243,0.00002473855,0.000013575487,0.000013029322,3.0257496e-7,0.00013835313,0.45231813,0.5473366,0.00006467271,2.8365955e-7,0.00007245225],"study_design_scores_gemma":[0.00033635538,0.000029839184,0.00019659982,0.000023745804,0.0000117197,0.0000147303135,0.000015083061,0.062036324,0.9372071,0.00005099635,0.000016125347,0.00006134769],"about_ca_topic_score_codex":0.0001030476,"about_ca_topic_score_gemma":0.000015727797,"teacher_disagreement_score":0.3902818,"about_ca_system_score_codex":0.0000503791,"about_ca_system_score_gemma":0.0002240275,"threshold_uncertainty_score":0.18817799},"labels":[],"label_agreement":null},{"id":"W2058695076","doi":"10.1016/j.jbiotec.2012.05.013","title":"Integrated development of an effective bioprocess for extracellular production of penicillin G acylase in Escherichia coli and its subsequent one-step purification","year":2012,"lang":"en","type":"article","venue":"Journal of Biotechnology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Natrix Separations (Canada); University of Waterloo","funders":"","keywords":"Bioprocess; Lysis; Extracellular; Chromatography; Downstream processing; Chemistry; Size-exclusion chromatography; Escherichia coli; Ultrafiltration (renal); Ion exchange; Penicillin amidase; Ion chromatography; Fast protein liquid chromatography; Biochemistry; Enzyme; Biology; High-performance liquid chromatography; Ion","score_opus":0.019475138498844087,"score_gpt":0.2684962368899957,"score_spread":0.2490210983911516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058695076","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9874907,0.004208548,0.0074632782,0.00023044528,0.00007315604,0.00052293437,0.0000054737984,0.0000034688258,0.0000019930048],"genre_scores_gemma":[0.98564374,0.00017931747,0.014079223,0.0000041044723,0.000027704858,0.000029055858,0.000018920555,0.0000070482806,0.000010881729],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990685,0.00007192769,0.00050498673,0.00014963334,0.000079396734,0.00012557376],"domain_scores_gemma":[0.99900854,0.0000094949255,0.0005046173,0.00015389927,0.00028006104,0.000043390653],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00096877816,0.00008759983,0.00020729276,0.00014241363,0.000022706745,0.0000025602146,0.00012630688,0.00028389067,0.0000022645577],"category_scores_gemma":[0.0003784215,0.00007817036,0.00003417521,0.00014531732,0.000094362105,0.000016550106,0.000022311326,0.00012986721,2.1259024e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003768119,0.0004381236,0.00050601206,0.000103599355,0.000031422165,1.2957257e-7,0.00017193526,0.0000059151394,0.9757279,0.00021541919,0.0000017076165,0.022421032],"study_design_scores_gemma":[0.0004969141,0.00043554298,0.008799088,0.000023358556,0.000015402185,0.000010547522,0.00026230645,0.00008351814,0.98818046,0.00005427409,0.0015657214,0.00007286221],"about_ca_topic_score_codex":0.0000033122449,"about_ca_topic_score_gemma":0.0000220671,"teacher_disagreement_score":0.02234817,"about_ca_system_score_codex":0.000038186183,"about_ca_system_score_gemma":0.000101886144,"threshold_uncertainty_score":0.31876945},"labels":[],"label_agreement":null},{"id":"W2060750406","doi":"10.1002/ceat.200700413","title":"Separation of Shikimic Acid from Pine Needles","year":2008,"lang":"en","type":"article","venue":"Chemical Engineering & Technology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Shikimic acid; Chemistry; Adsorption; Desorption; Crystallization; Chromatography; Organic chemistry","score_opus":0.006828580443087106,"score_gpt":0.21476219410129352,"score_spread":0.20793361365820642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060750406","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9769694,0.0012896797,0.021247586,0.00018352283,0.00003930485,0.000077310826,0.00001314703,0.0000805946,0.00009941089],"genre_scores_gemma":[0.9944333,0.000060619415,0.0052832756,0.000019306744,0.000045932054,0.000024653687,0.00009570797,0.000010569055,0.000026670159],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99944496,0.000004040342,0.0001724427,0.00020572633,0.000051694027,0.00012115941],"domain_scores_gemma":[0.9995467,0.000005844682,0.000039695773,0.00033187334,0.00004495034,0.000030901305],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000031007115,0.00009249759,0.00012749028,0.00004921955,0.000014736703,0.0000014042806,0.0001713001,0.00026338687,0.000012200731],"category_scores_gemma":[0.00019909488,0.000097159835,0.000043210435,0.00012879662,0.00010952718,0.0000021258531,0.000060553888,0.00010175104,0.0000051152138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012576591,0.000029591383,0.0003399371,0.000007642237,0.000014310932,6.23117e-7,0.000014604859,0.00008129259,0.99864113,0.0001564575,0.00007553401,0.0006262819],"study_design_scores_gemma":[0.0001859961,0.000033734577,0.00048803116,0.0000046322934,0.0000038580706,0.000009945494,0.0000066491243,0.0005267527,0.9941251,0.00012999446,0.00439198,0.00009328958],"about_ca_topic_score_codex":0.0000040248524,"about_ca_topic_score_gemma":1.6215243e-7,"teacher_disagreement_score":0.017463822,"about_ca_system_score_codex":0.000012651045,"about_ca_system_score_gemma":0.00002628871,"threshold_uncertainty_score":0.39620632},"labels":[],"label_agreement":null},{"id":"W2061120223","doi":"10.1002/bit.24349","title":"Zonal rate model for stacked membrane chromatography part II: Characterizing ion‐exchange membrane chromatography under protein retention conditions","year":2011,"lang":"en","type":"editorial","venue":"Biotechnology and Bioengineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Intertek (Canada); Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Chromatography; Membrane; Elution; Volumetric flow rate; Mass transfer; Ion chromatography; Analytical Chemistry (journal); Biological system; Thermodynamics; Physics; Biochemistry","score_opus":0.016392465786369027,"score_gpt":0.23179826249809277,"score_spread":0.21540579671172375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061120223","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6440575,0.015956562,0.100673385,0.0029780495,0.21315445,0.009693001,0.01148542,0.0018626116,0.00013897521],"genre_scores_gemma":[0.82159984,0.014055429,0.009735705,0.00023316246,0.11834652,0.005730496,0.028279264,0.00045958685,0.0015600058],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99769497,0.000055245506,0.00053071766,0.0009928923,0.00017846651,0.00054770254],"domain_scores_gemma":[0.9986774,0.000026187296,0.00029338783,0.00068699766,0.00018766374,0.00012839111],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00048963766,0.0005473766,0.0005108795,0.00041658554,0.00038246135,0.00004386754,0.00035925864,0.0027824172,0.0000230734],"category_scores_gemma":[0.00013491277,0.0005632574,0.0002960696,0.0002628003,0.00039253442,0.000020993954,0.00020397044,0.0005600443,0.0000022552465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015089843,0.00011593446,0.00000353678,0.0007409974,0.00034768402,0.0000014938521,0.000026338394,0.00001417069,0.9866493,0.0014067058,0.010332349,0.00021061813],"study_design_scores_gemma":[0.0011510097,0.00044661682,0.000045120745,0.00021535206,0.00014603318,0.0000082768665,0.000022790146,0.00200722,0.581223,0.00036682078,0.4135277,0.0008400774],"about_ca_topic_score_codex":0.000009219248,"about_ca_topic_score_gemma":0.000022532993,"teacher_disagreement_score":0.4054263,"about_ca_system_score_codex":0.00002591613,"about_ca_system_score_gemma":0.000120975514,"threshold_uncertainty_score":0.9996819},"labels":[],"label_agreement":null},{"id":"W2061685804","doi":"10.1021/ja804544x","title":"“Inject-Mix-React-Separate-and-Quantitate” (IMReSQ) Method for Screening Enzyme Inhibitors","year":2008,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Chemistry; Enzyme; Capillary electrophoresis; Substrate (aquarium); Product inhibition; Combinatorial chemistry; Biochemistry; Chromatography; Non-competitive inhibition","score_opus":0.022014619295639765,"score_gpt":0.30663000026613624,"score_spread":0.2846153809704965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061685804","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9636178,0.00074382505,0.0338396,0.0015271114,0.00006461597,0.00014508396,0.0000111012205,0.0000052451564,0.00004559853],"genre_scores_gemma":[0.9313006,0.0002615254,0.06710528,0.0009303933,0.00027412066,0.000008289933,0.0000039828633,0.000014372202,0.00010148717],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900883,0.000087974615,0.00033903323,0.00019025689,0.00018286354,0.00019103894],"domain_scores_gemma":[0.9989245,0.00008195813,0.00048758736,0.00022441162,0.00017492019,0.0001066273],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005669416,0.00012462515,0.00025416247,0.000009209484,0.00014022575,0.00001360192,0.00027365534,0.00007685991,0.0000028990112],"category_scores_gemma":[0.00029992723,0.000085663734,0.0004967608,0.0001231953,0.0003920273,0.0000069478315,0.000101496946,0.00021236806,4.13837e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016181103,0.00005266497,0.0016469487,0.000008605998,0.000094466835,3.5423375e-7,0.00015896636,0.000014251443,0.9872011,0.000014365568,0.008275279,0.0023711785],"study_design_scores_gemma":[0.00056901446,0.0001943366,0.0026361283,0.000010157457,0.000036135396,0.00012264837,0.00025496352,0.00025853913,0.9540627,0.00011708568,0.041594297,0.00014398411],"about_ca_topic_score_codex":0.000017961,"about_ca_topic_score_gemma":5.2747066e-7,"teacher_disagreement_score":0.03331902,"about_ca_system_score_codex":0.000026389549,"about_ca_system_score_gemma":0.00009225072,"threshold_uncertainty_score":0.34932658},"labels":[],"label_agreement":null},{"id":"W2062178312","doi":"10.1074/jbc.m205314200","title":"The Influence of Protein Structure on the Products Emerging from Succinimide Hydrolysis","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Plant Biotechnology Institute; University of Saskatchewan","funders":"","keywords":"Succinimide; Deamidation; Chemistry; Residue (chemistry); Hydrolysis; Stereochemistry; Covalent bond; Histidine; Amino acid; Organic chemistry; Biochemistry; Enzyme","score_opus":0.01516598835716651,"score_gpt":0.2259304384395156,"score_spread":0.2107644500823491,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062178312","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99513966,0.0017124078,0.0000072661587,0.0027643614,0.000020534657,0.000110852336,0.00001954637,0.0000027001433,0.00022265538],"genre_scores_gemma":[0.9992,0.0002660568,0.00010031492,0.00010979824,0.00018573485,0.0000054767893,0.0000049305613,0.000004212114,0.00012348357],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990265,0.00010198772,0.00038832737,0.00017676025,0.00017204415,0.00013442147],"domain_scores_gemma":[0.99885637,0.00007279339,0.000417074,0.00039929675,0.0002060151,0.000048479902],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003417279,0.00011260538,0.0001485125,0.000005880331,0.00010801643,0.000016169777,0.0004705179,0.0001429458,0.000101553625],"category_scores_gemma":[0.0017946361,0.00005123013,0.000110014684,0.00008979684,0.0002109909,0.0000030865658,0.000057936035,0.00026302141,0.0000012497782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000094878706,0.00004596724,0.0009035337,0.0000068516924,0.000041024454,0.0000011197941,0.000017692144,0.000067966444,0.9970707,0.000014382428,0.00014854672,0.0015872788],"study_design_scores_gemma":[0.00014380211,0.000110816145,0.0070120087,0.000016918983,0.000007824621,0.000008347845,0.000049362665,0.000015034326,0.9803954,0.00046113887,0.011708128,0.000071221635],"about_ca_topic_score_codex":0.0000026435473,"about_ca_topic_score_gemma":5.889111e-7,"teacher_disagreement_score":0.016675362,"about_ca_system_score_codex":0.000011463843,"about_ca_system_score_gemma":0.000024844016,"threshold_uncertainty_score":0.21484767},"labels":[],"label_agreement":null},{"id":"W2062433186","doi":"10.1002/rcm.571","title":"Microwave‐assisted protein staining: mass spectrometry compatible methods for rapid protein visualisation","year":2002,"lang":"en","type":"article","venue":"Rapid Communications in Mass Spectrometry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences; Institute for Marine Biosciences","funders":"","keywords":"Chemistry; Staining; Mass spectrometry; Microwave; Chromatography; Trypsin; Polyacrylamide gel electrophoresis; Molecular mass; Gel electrophoresis; Analytical Chemistry (journal); Biochemistry; Enzyme; Pathology","score_opus":0.06478975291830309,"score_gpt":0.36059730163519677,"score_spread":0.2958075487168937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062433186","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.12500434,0.016831908,0.8332859,0.0039973794,0.00013746844,0.0060539325,0.00012172709,0.00021133371,0.014356003],"genre_scores_gemma":[0.53721374,0.00036718746,0.4603704,0.000071185095,0.00006119783,0.0010687042,0.00030299125,0.00004380187,0.00050077157],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9959486,0.0013984101,0.00094712427,0.0008056893,0.00025826256,0.000641915],"domain_scores_gemma":[0.9955777,0.00019916348,0.00044792335,0.0033326254,0.0002854623,0.0001571252],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002374263,0.00040003494,0.0004898744,0.0006270251,0.00041876672,0.0001251795,0.0015694565,0.00035630233,0.00041946233],"category_scores_gemma":[0.001090969,0.0004484281,0.0002598507,0.0014720982,0.00034125088,0.000034492743,0.00025932808,0.0005182865,0.000024160776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000886068,0.0005941544,0.00048523326,0.00008116959,0.00008960048,3.7259747e-7,0.00013579297,0.0000046444447,0.97188723,0.008187456,0.0001564363,0.018289298],"study_design_scores_gemma":[0.0027633377,0.0010463421,0.003322314,0.00008736539,0.0000467017,0.000012186883,0.00084648025,0.008500712,0.9134574,0.012082081,0.056824766,0.0010103117],"about_ca_topic_score_codex":0.000018852048,"about_ca_topic_score_gemma":0.000029358598,"teacher_disagreement_score":0.41220942,"about_ca_system_score_codex":0.00030587454,"about_ca_system_score_gemma":0.0001084604,"threshold_uncertainty_score":0.99979675},"labels":[],"label_agreement":null},{"id":"W2063502259","doi":"10.1016/j.pep.2011.08.030","title":"A screening strategy for heterologous protein expression in Escherichia coli with the highest return of investment","year":2011,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Structural Genomics Consortium","funders":"Canadian Institutes of Health Research; Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Stiftelsen för Strategisk Forskning; Ontario Innovation Trust; Wellcome Trust; Petroleum Technology Research Centre; Novartis Foundation; Merck; GlaxoSmithKline","keywords":"Escherichia coli; Heterologous; Inclusion bodies; Heterologous expression; Recombinant DNA; Biology; Biochemistry; Target protein; Molecular biology; Chemistry; Computational biology; Gene","score_opus":0.033968956588862446,"score_gpt":0.25317819527375146,"score_spread":0.219209238684889,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063502259","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9714509,0.0009326916,0.023746803,0.00033529097,0.000012127211,0.0031481097,0.000017253049,0.00001702048,0.00033976854],"genre_scores_gemma":[0.9800487,0.00002135599,0.017424146,0.00007842026,0.000026807995,0.0021422626,0.000060175138,0.000017133809,0.00018097127],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875325,0.00021516088,0.00030298045,0.00040575257,0.00013833617,0.00018451297],"domain_scores_gemma":[0.999084,0.000012443249,0.00026791665,0.00046424108,0.00010221212,0.00006918242],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049127237,0.00016229086,0.00015066026,0.000043239957,0.00011880689,0.000018926805,0.00019731201,0.00016374375,0.0000126854075],"category_scores_gemma":[0.00006781197,0.000105709354,0.000038072547,0.00009494353,0.00015808221,0.0000164207,0.0000510648,0.000118732925,4.0048278e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00089949276,0.00014710057,0.00055220805,0.00007259326,0.0000067075944,2.2936072e-7,0.00035686936,0.000006218647,0.99523026,0.00030999427,0.000045091558,0.0023732283],"study_design_scores_gemma":[0.0008123918,0.0005012875,0.008759643,0.00010647283,0.0000055161872,9.973153e-7,0.00022888507,0.0001265168,0.98484325,0.000497054,0.003975262,0.00014272453],"about_ca_topic_score_codex":0.000030503063,"about_ca_topic_score_gemma":0.000020528543,"teacher_disagreement_score":0.010387016,"about_ca_system_score_codex":0.000009396225,"about_ca_system_score_gemma":0.000047643684,"threshold_uncertainty_score":0.43107024},"labels":[],"label_agreement":null},{"id":"W2064443662","doi":"10.1007/s10973-005-7052-6","title":"Thermogravimetry and vapor pressure moisture","year":2006,"lang":"en","type":"article","venue":"Journal of Thermal Analysis and Calorimetry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Réseau Technoscience","funders":"","keywords":"Thermogravimetry; Moisture; Vapor pressure; Vapour pressure of water; Chemistry; Analytical Chemistry (journal); Materials science; Chromatography; Organic chemistry; Inorganic chemistry","score_opus":0.0033521783965302344,"score_gpt":0.21650791835929545,"score_spread":0.2131557399627652,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064443662","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9748861,0.02251605,0.0018567523,0.00014358875,0.000035240326,0.00003884202,0.000011124947,0.0000022297604,0.0005100722],"genre_scores_gemma":[0.998569,0.00018695326,0.0004532983,0.000072292016,0.00023500946,7.883315e-7,0.000009682723,0.0000057058014,0.0004672586],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99927646,0.00007031979,0.0002681643,0.00015078526,0.00013604567,0.000098242745],"domain_scores_gemma":[0.9994324,0.000010520125,0.00020926815,0.00016232455,0.00011391264,0.00007159898],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034210412,0.000098370925,0.0002195432,0.00010317699,0.000057995054,0.00003252988,0.00009748753,0.0001046243,0.000031295414],"category_scores_gemma":[0.000030823903,0.00006959738,0.0001844021,0.00021323065,0.000071578776,0.0000060940647,0.000037084985,0.00010857791,3.031521e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000235766,0.00019972977,0.47680718,0.000034462828,0.0020103117,0.0000073645656,0.000032144213,0.00012114431,0.5024173,0.00023332899,0.00035998703,0.01754123],"study_design_scores_gemma":[0.00042545394,0.00015382326,0.94047505,0.000003741761,0.0010667722,0.00002385255,0.000052697924,0.000078445744,0.038725458,0.00022594337,0.018622162,0.00014657744],"about_ca_topic_score_codex":0.00006871009,"about_ca_topic_score_gemma":0.000014699854,"teacher_disagreement_score":0.4636919,"about_ca_system_score_codex":0.0000032859662,"about_ca_system_score_gemma":0.000017113274,"threshold_uncertainty_score":0.2838099},"labels":[],"label_agreement":null},{"id":"W2069285500","doi":"10.1016/j.jim.2013.04.008","title":"Coupled affinity and sizing chromatography: A novel in-process analytical tool to measure titer and trend Fc-protein aggregation","year":2013,"lang":"en","type":"article","venue":"Journal of Immunological Methods","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Monoclonal antibody; Sizing; Titer; Affinity chromatography; Chromatography; Size-exclusion chromatography; Quality by Design; Protein aggregation; Chemistry; Antibody; Biology; Biochemistry; Enzyme; Particle size; Immunology","score_opus":0.03283006226472862,"score_gpt":0.33783499503552256,"score_spread":0.30500493277079394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069285500","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9715892,0.002619793,0.024876282,0.0005849448,0.00002781607,0.00023162356,0.0000022202498,0.0000041349754,0.000063961226],"genre_scores_gemma":[0.8815858,0.00009033517,0.11814586,0.00011294565,0.000029261842,0.000019162755,0.000001624609,0.0000050787608,0.000009921465],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99886954,0.00024957725,0.00040284105,0.00020589067,0.00011665766,0.00015552143],"domain_scores_gemma":[0.9993657,0.00006090861,0.00016214717,0.00015065895,0.00017089772,0.00008971159],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012966201,0.00012010405,0.00025246944,0.00009799945,0.00004660479,0.00005186658,0.00012441284,0.00017648007,0.000031603442],"category_scores_gemma":[0.001631765,0.00008673246,0.000067168,0.00018075183,0.00011294008,0.000018263161,0.00006391252,0.0002165006,8.4609286e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000216257,0.00010949453,0.0025268258,0.00001556415,0.000039353687,0.0000013763422,0.00006329101,0.0000036972529,0.90007097,0.000095391944,0.0000025274144,0.09685526],"study_design_scores_gemma":[0.0032855382,0.0024576092,0.75603473,0.0001851022,0.00005543235,0.0001813158,0.0005414081,0.0013778885,0.22891551,0.0039320197,0.002456002,0.0005774224],"about_ca_topic_score_codex":0.0000076164524,"about_ca_topic_score_gemma":0.000003906273,"teacher_disagreement_score":0.7535079,"about_ca_system_score_codex":0.000013567065,"about_ca_system_score_gemma":0.000031198546,"threshold_uncertainty_score":0.35368472},"labels":[],"label_agreement":null},{"id":"W2069597763","doi":"10.1016/j.idairyj.2008.04.004","title":"Separation of minor protein components from whey protein isolates by heparin affinity chromatography","year":2008,"lang":"en","type":"article","venue":"International Dairy Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chromatography; Chemistry; Whey protein; Affinity chromatography; Ultrafiltration (renal); Whey protein isolate; Ion chromatography; Biochemistry","score_opus":0.015972672432671368,"score_gpt":0.25966638672374176,"score_spread":0.2436937142910704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069597763","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940293,0.0006084115,0.0036384482,0.0003610865,0.00015162372,0.00028984543,0.00018709897,0.000010570677,0.0007236241],"genre_scores_gemma":[0.99681073,0.000079447724,0.0019174916,0.000052548614,0.00017474362,0.000036545094,0.00042177158,0.000011108937,0.00049561966],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987846,0.000116837015,0.0004384941,0.00023477999,0.00029044537,0.00013481628],"domain_scores_gemma":[0.9990876,0.000007076588,0.00031860318,0.00020684942,0.0002862521,0.00009361693],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019851695,0.00013458947,0.00013973856,0.00006683946,0.0001266957,0.000031249703,0.0003477817,0.00011452045,0.00017055527],"category_scores_gemma":[0.000104608895,0.00012915838,0.00013821047,0.00006021051,0.00011744358,0.000023254057,0.00006318812,0.00016468372,0.0000122339725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024256855,0.00029514587,0.020456648,0.000005112507,0.0001136046,0.000002731214,0.00006007163,0.000008559534,0.9762603,0.000042700092,0.0019278907,0.0005846495],"study_design_scores_gemma":[0.0011110691,0.00019291369,0.043408904,0.00003712431,0.00000784749,0.00006555904,0.000030553787,0.00023846439,0.909639,0.0006931284,0.044365093,0.00021033474],"about_ca_topic_score_codex":0.0001182726,"about_ca_topic_score_gemma":0.000019163923,"teacher_disagreement_score":0.06662131,"about_ca_system_score_codex":0.000025793772,"about_ca_system_score_gemma":0.0000801766,"threshold_uncertainty_score":0.52669257},"labels":[],"label_agreement":null},{"id":"W2070420959","doi":"10.1016/j.jchromb.2011.01.017","title":"Potential application of hydrogel-based strong anion-exchange membrane for plasmid DNA purification","year":2011,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Natrix Separations (Canada); University of Waterloo","funders":"","keywords":"Chemistry; Membrane; Plasmid; Chromatography; Adsorption; Ion exchange; DNA; Porosity; Plasmid preparation; Environmental scanning electron microscope; Chemical engineering; Scanning electron microscope; Biochemistry; Ion; Organic chemistry; Materials science","score_opus":0.013037161117901272,"score_gpt":0.2371437376883171,"score_spread":0.22410657657041583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070420959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7875869,0.00088744273,0.21056789,0.00008699579,0.0001112375,0.0004264567,0.00004412889,0.0000075647918,0.00028137607],"genre_scores_gemma":[0.99326336,0.000070056856,0.0064157476,0.000032389027,0.00010594159,0.0000391925,0.00005550871,0.000012754234,0.000005057951],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990467,0.0000403251,0.00046522074,0.0001593295,0.00016517813,0.0001232434],"domain_scores_gemma":[0.99866235,0.000009475152,0.00062029203,0.00028660017,0.0003447735,0.00007648051],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004197621,0.00010371635,0.00017254298,0.00013316656,0.00004695546,0.0000066649236,0.00022058048,0.000119827964,0.000020056956],"category_scores_gemma":[0.000037093687,0.0000956893,0.00028368802,0.0001326538,0.00009451486,0.000010517566,0.00001149843,0.00005781274,6.4646736e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043530262,0.0003689847,0.0025818883,0.00013292927,0.00008693964,3.5429014e-7,0.00005784342,0.00002484956,0.9926411,0.00052997546,0.00013536411,0.003004449],"study_design_scores_gemma":[0.0010445379,0.0004727298,0.010170942,0.00001434033,0.00005301125,0.000012742944,0.000044193115,0.000432458,0.98086125,0.00038082575,0.0064032897,0.00010968917],"about_ca_topic_score_codex":0.0000046886057,"about_ca_topic_score_gemma":0.0000031242894,"teacher_disagreement_score":0.20567644,"about_ca_system_score_codex":0.000007791739,"about_ca_system_score_gemma":0.00007501244,"threshold_uncertainty_score":0.39020965},"labels":[],"label_agreement":null},{"id":"W2070692780","doi":"10.1002/cjce.22026","title":"Adsorption optimization of acyclovir on prepared activated carbon","year":2014,"lang":"en","type":"article","venue":"The Canadian Journal of Chemical Engineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"University of Saskatchewan","funders":"Canada Research Chairs; University of Saskatchewan","keywords":"Conifer cone; Adsorption; Aqueous solution; Activated carbon; Chemistry; Nuclear chemistry; Canola; Response surface methodology; Materials science; Chromatography; Organic chemistry; Botany","score_opus":0.005157776670508814,"score_gpt":0.18763762657553537,"score_spread":0.18247984990502655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070692780","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954914,0.000074039934,0.0038787012,0.00019000564,0.000059885577,0.00005220631,0.0000020777509,0.0000022821891,0.00024941048],"genre_scores_gemma":[0.99943894,0.0000020803893,0.0004283111,0.000025916046,0.00008322929,0.0000014048292,0.0000060287066,0.000006877734,0.0000072053667],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996176,0.00002073092,0.00015517109,0.000056219145,0.000066819026,0.00008347009],"domain_scores_gemma":[0.9995745,0.000012969875,0.000085355656,0.00013899078,0.000084855754,0.00010332621],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019535447,0.00005264985,0.00007415556,0.000033189102,0.000011614233,0.0000065435474,0.00012237775,0.00006416287,0.0000057244674],"category_scores_gemma":[0.00041380024,0.00004167715,0.000039911618,0.0000522246,0.000027245187,0.0000022563102,0.000004952097,0.00008828365,1.1458478e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023595738,0.000004376571,0.000039911945,0.0000060094817,0.0000112197595,9.8983406e-8,0.000021515925,0.13542189,0.86412835,0.000058482412,0.00001176435,0.00027279073],"study_design_scores_gemma":[0.00016074612,0.000054012555,0.00011983117,0.000017210716,0.0000062763993,0.0000063103566,0.0000020938319,0.023136128,0.9757358,0.000016579435,0.00069752836,0.000047477744],"about_ca_topic_score_codex":0.00009274257,"about_ca_topic_score_gemma":0.000020551843,"teacher_disagreement_score":0.11228576,"about_ca_system_score_codex":0.000035269062,"about_ca_system_score_gemma":0.00009812375,"threshold_uncertainty_score":0.16995448},"labels":[],"label_agreement":null},{"id":"W2071539848","doi":"10.1002/cjce.5450850608","title":"Comparative Analysis of Single‐Cascade Five‐Zone and Two‐Zone SMB Systems for the Separation of a Ternary Amino Acid Mixture","year":2007,"lang":"en","type":"article","venue":"The Canadian Journal of Chemical Engineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Simulated moving bed; Separation (statistics); Ternary operation; Cascade; Margin (machine learning); Chromatography; Materials science; Chemistry; Computer science; Mathematics; Statistics; Adsorption","score_opus":0.012396776799474105,"score_gpt":0.25110678043252366,"score_spread":0.23871000363304956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071539848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93591386,0.005786519,0.05790553,0.00014477548,0.000046978334,0.00013565345,0.000034892662,9.9798e-7,0.000030765867],"genre_scores_gemma":[0.9995098,0.000009171874,0.00034854232,0.000015590416,0.000077944525,0.0000026530506,0.000010761882,0.0000038765706,0.000021621901],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994373,0.000015979662,0.00028780696,0.00006851125,0.000080795675,0.00010960859],"domain_scores_gemma":[0.99935734,0.00007086334,0.00017367805,0.00013578733,0.00015849268,0.000103856626],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043267253,0.00007013864,0.00019795794,0.00006695543,0.000029427332,0.000010754401,0.0001430298,0.000062208215,0.000001636142],"category_scores_gemma":[0.00009537025,0.000046588822,0.00009491931,0.00014024411,0.000086290136,0.0000042734505,0.000008410912,0.0000892823,2.4118343e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042874624,0.000008331199,0.0001747937,0.000022815628,0.00035500465,6.1817803e-7,0.00026814052,0.012057741,0.9867362,0.000079589125,0.000030958356,0.00022296554],"study_design_scores_gemma":[0.00027509232,0.000074604584,0.0015470856,0.000021716802,0.00022670689,0.000023906277,0.000100213976,0.021299653,0.9749163,0.0000039683127,0.0014433751,0.00006739914],"about_ca_topic_score_codex":0.00026610796,"about_ca_topic_score_gemma":0.00035063908,"teacher_disagreement_score":0.06359595,"about_ca_system_score_codex":0.00003137331,"about_ca_system_score_gemma":0.00007258144,"threshold_uncertainty_score":0.1899837},"labels":[],"label_agreement":null},{"id":"W2075267052","doi":"10.1002/prot.1092","title":"Substrate flow in catalases deduced from the crystal structures of active site variants of HPII from <i>Escherichia coli</i>","year":2001,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; European Commission; North Atlantic Treaty Organization","keywords":"Active site; Escherichia coli; Substrate (aquarium); Flow (mathematics); Crystal (programming language); Chemistry; Materials science; Biology; Enzyme; Physics; Biochemistry; Computer science; Mechanics; Ecology; Gene","score_opus":0.007916361566893529,"score_gpt":0.20727031608662197,"score_spread":0.19935395451972843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075267052","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930554,0.00033044632,0.0045034215,0.00007796438,0.000105592524,0.0005452309,0.0012622685,0.000007998927,0.00011168445],"genre_scores_gemma":[0.9934667,0.000095902935,0.0054299496,0.00014147158,0.000066902125,0.000014718746,0.00076755846,0.000008164344,0.000008648962],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99899065,0.00007860919,0.00043791078,0.00018609715,0.00016212875,0.0001445867],"domain_scores_gemma":[0.99916834,0.000033234894,0.00029095184,0.00034550493,0.00010858289,0.000053406926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010894475,0.00017186544,0.00020592581,0.000033293778,0.00006919075,0.000023215644,0.00013970205,0.00018087984,0.00008211474],"category_scores_gemma":[0.00012784041,0.00012055596,0.0000537177,0.00016362971,0.00014979985,0.000024185993,0.000060512924,0.00014562765,6.1143027e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011266996,0.00006260606,0.022868803,0.000063180414,0.000105046594,4.3183502e-7,0.0015122041,0.00008228597,0.955899,0.00009636831,0.000046399648,0.018136984],"study_design_scores_gemma":[0.0013511236,0.00022673534,0.5708761,0.000030270392,0.000046813442,0.0000032440475,0.0010433177,0.0023297905,0.42007905,0.0023000569,0.0014856204,0.00022787569],"about_ca_topic_score_codex":0.0005202042,"about_ca_topic_score_gemma":0.0010280551,"teacher_disagreement_score":0.5480073,"about_ca_system_score_codex":0.000010900021,"about_ca_system_score_gemma":0.00008733703,"threshold_uncertainty_score":0.49161294},"labels":[],"label_agreement":null},{"id":"W2076117093","doi":"10.1016/j.pep.2007.11.008","title":"The use of systematic N- and C-terminal deletions to promote production and structural studies of recombinant proteins","year":2007,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium","funders":"Wellcome Trust","keywords":"Recombinant DNA; Computational biology; Construct (python library); Escherichia coli; Human proteins; Crystallization; Biology; Function (biology); Biochemistry; Chemistry; Computer science; Gene; Genetics","score_opus":0.049006939188802966,"score_gpt":0.30921586821459457,"score_spread":0.2602089290257916,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076117093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909771,0.0039559123,0.0019451785,0.0004524282,0.000053263237,0.002600126,0.0000054088314,0.000006768474,0.0000037833363],"genre_scores_gemma":[0.9927396,0.0003999406,0.006353164,0.000007893833,0.00002008999,0.00027127212,0.000007369195,0.00000661869,0.0001940357],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895924,0.0001305778,0.00040661503,0.0002698814,0.00012419058,0.000109481836],"domain_scores_gemma":[0.999073,0.000029989053,0.00025677175,0.00032750113,0.00025189764,0.000060803457],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00081316684,0.00010194567,0.00015876096,0.00004443889,0.00020515936,0.000023377264,0.00006610579,0.000067603636,5.1958745e-7],"category_scores_gemma":[0.001208921,0.000066638924,0.000020035202,0.000079220066,0.0001971118,0.000016097369,0.00006350968,0.000052960557,1.3945525e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018261679,0.000028429196,0.00046044897,0.0018409931,0.00001467464,9.829308e-8,0.00048273228,0.0000010007808,0.98827004,0.00039909213,0.000016471355,0.008303368],"study_design_scores_gemma":[0.00017954012,0.00031859442,0.009742994,0.0011015387,0.00001990907,0.00001762399,0.0004650524,0.00006339523,0.9860872,0.0005037,0.0013782192,0.00012221462],"about_ca_topic_score_codex":0.000007800385,"about_ca_topic_score_gemma":0.00001608295,"teacher_disagreement_score":0.009282545,"about_ca_system_score_codex":0.0000071811583,"about_ca_system_score_gemma":0.00001694185,"threshold_uncertainty_score":0.27174565},"labels":[],"label_agreement":null},{"id":"W2079296237","doi":"10.1007/s00449-007-0167-3","title":"Applicability of airlift draft-tube fluidized bioreactors for binary protein mixture bioseparation","year":2007,"lang":"en","type":"article","venue":"Bioprocess and Biosystems Engineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Toronto Metropolitan University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Airlift; Adsorption; Bioreactor; Draft tube; Chromatography; Materials science; Mixing (physics); Compressibility; Homogeneous; Chemical engineering; Fluidized bed; Chemistry; Thermodynamics; Organic chemistry; Engineering","score_opus":0.006145667306837821,"score_gpt":0.23325715674997416,"score_spread":0.22711148944313633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079296237","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.969361,0.0021258795,0.027153548,0.000050371404,0.000077864024,0.0010924742,0.00006604002,0.000037398382,0.000035405377],"genre_scores_gemma":[0.99775577,0.000023698873,0.0018085351,0.000008195875,0.0001348937,0.00013367042,0.00008818388,0.0000171868,0.000029848694],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989498,0.000011205018,0.00037030462,0.00035660222,0.00010337446,0.00020867749],"domain_scores_gemma":[0.9993752,0.000014752974,0.00011019504,0.00025915506,0.00015090051,0.000089744135],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00059859356,0.00017052396,0.00020335645,0.00006193626,0.000052668536,0.00001655297,0.000113005415,0.0002234801,0.0000014590083],"category_scores_gemma":[0.00010672033,0.0001476163,0.000074489864,0.00014716209,0.000048377256,0.000008011868,0.00003328255,0.000050231112,3.075635e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012303052,0.00005459054,0.0006895023,0.000727342,0.000020721203,1.7255296e-7,0.000034851102,0.0000069061925,0.9968433,0.00027201543,0.000010920031,0.001216659],"study_design_scores_gemma":[0.00044392844,0.00018242627,0.0021091856,0.000044142937,0.00000943519,0.0000033915378,0.000069493355,0.0004979313,0.9829804,0.000009199495,0.013452673,0.00019780289],"about_ca_topic_score_codex":0.00001590713,"about_ca_topic_score_gemma":0.000008592298,"teacher_disagreement_score":0.028394768,"about_ca_system_score_codex":0.000014808857,"about_ca_system_score_gemma":0.000032815205,"threshold_uncertainty_score":0.6019618},"labels":[],"label_agreement":null},{"id":"W2080683672","doi":"10.1016/j.jbiotec.2015.04.003","title":"Comparing multi-module connections in membrane chromatography scale-up","year":2015,"lang":"en","type":"article","venue":"Journal of Biotechnology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"Sanofi Pasteur","keywords":"Biopharmaceutical; Context (archaeology); Membrane; Chemistry; Chromatography; Adsorption; Scale (ratio); Series (stratigraphy); Process engineering; Computer science; Engineering; Organic chemistry; Biochemistry; Biotechnology; Biology; Physics","score_opus":0.031691737963406734,"score_gpt":0.27802497755136557,"score_spread":0.24633323958795883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080683672","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98927385,0.001484001,0.0073035215,0.0014340777,0.00027370936,0.00009379753,0.0000025204038,0.000014120438,0.000120395984],"genre_scores_gemma":[0.99679357,0.00018107392,0.0028775777,0.000056615667,0.000045410743,0.0000041510884,0.00000379322,0.0000070082738,0.00003079337],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992067,0.00006137584,0.00035094842,0.00014703236,0.000086280335,0.0001476571],"domain_scores_gemma":[0.99937004,0.0000058964715,0.00018742295,0.00024908542,0.00010942032,0.000078136596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043957232,0.00008392851,0.00019738202,0.0002291184,0.000028727074,0.00000888047,0.00023155252,0.0002875694,0.0000052866753],"category_scores_gemma":[0.00020421715,0.00007718817,0.00008247155,0.0002332036,0.00015768474,0.000005695631,0.00005846924,0.0002362385,0.0000040228006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014479853,0.00028356846,0.04246041,0.00001210285,0.000043618067,0.000006851448,0.000076005505,0.0000965013,0.95420086,0.00038569496,0.00032882404,0.0019607795],"study_design_scores_gemma":[0.0024406773,0.00038342783,0.020570492,0.000017480776,0.000011026689,0.00028689078,0.00045713608,0.00029260287,0.9470347,0.000257928,0.028101832,0.0001458151],"about_ca_topic_score_codex":0.00002076917,"about_ca_topic_score_gemma":0.00023652188,"teacher_disagreement_score":0.027773006,"about_ca_system_score_codex":0.000025764963,"about_ca_system_score_gemma":0.000080529724,"threshold_uncertainty_score":0.3147642},"labels":[],"label_agreement":null},{"id":"W2081000220","doi":"10.1021/la015697w","title":"Colloidal Flocculation with Poly(ethylene oxide)/Polypeptide Complexes","year":2002,"lang":"en","type":"article","venue":"Langmuir","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McMaster University","funders":"","keywords":"Flocculation; Ethylene oxide; Colloid; Poly ethylene; Chemical engineering; Oxide; Chemistry; Polymer chemistry; Materials science; Ethylene; Polymer science; Polymer; Organic chemistry; Copolymer; Catalysis; Engineering","score_opus":0.014360810087859386,"score_gpt":0.22347243193668798,"score_spread":0.2091116218488286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081000220","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905214,0.0013868588,0.0019122165,0.0005927988,0.00002571126,0.0001783953,0.000027237204,0.000036678262,0.0053187483],"genre_scores_gemma":[0.9956508,0.000019496683,0.0015397515,0.0002791302,0.00008698739,0.000024138983,0.00009907889,0.000011996608,0.0022886165],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99938536,0.000038112954,0.00011102811,0.00021851025,0.000102576116,0.00014440076],"domain_scores_gemma":[0.9995928,0.0000049977452,0.000043899377,0.00026151913,0.000047420708,0.000049370494],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006531275,0.00009400749,0.00008461448,0.000019366002,0.00008427806,0.000017638018,0.000098332624,0.000071815964,0.00013922907],"category_scores_gemma":[0.000020831416,0.00007872377,0.000035783327,0.000076901124,0.00006444502,0.0000034537234,0.00002566182,0.00004750659,0.000048221384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008795826,0.00012187133,0.01883541,0.000020763138,0.00003870144,0.0000028116076,0.000117284515,0.00001694745,0.9709777,0.00083512865,0.003116759,0.005828623],"study_design_scores_gemma":[0.001124054,0.00023964196,0.19348378,0.000009351753,0.0000181973,0.000028059401,0.00010427087,0.00035937884,0.5274972,0.000105259074,0.27663898,0.00039185633],"about_ca_topic_score_codex":0.000034005992,"about_ca_topic_score_gemma":0.00006670431,"teacher_disagreement_score":0.44348058,"about_ca_system_score_codex":0.000010288552,"about_ca_system_score_gemma":0.000008842469,"threshold_uncertainty_score":0.32102624},"labels":[],"label_agreement":null},{"id":"W2081242290","doi":"10.1208/s12249-011-9598-x","title":"A QbD Case Study: Bayesian Prediction of Lyophilization Cycle Parameters","year":2011,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"U.S. Public Health Service; Hamilton Health Sciences Foundation","keywords":"Bayesian probability; SCALE-UP; Bayesian inference; Computer science; Process engineering; Scale (ratio); Artificial intelligence; Engineering","score_opus":0.037417927047775926,"score_gpt":0.272225213102602,"score_spread":0.2348072860548261,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081242290","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98694044,0.00011233125,0.011632593,0.000016077547,0.000086433756,0.00049722206,0.000035038065,0.000026015368,0.0006538292],"genre_scores_gemma":[0.998667,0.000019735093,0.0010891908,0.000036977577,0.000026923253,0.00006488511,0.000037168335,0.000011257489,0.000046868507],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991873,0.000084425985,0.0002329521,0.00027901834,0.00010155733,0.00011476254],"domain_scores_gemma":[0.9993565,0.000004815651,0.00009047842,0.00039797815,0.00009151463,0.000058733294],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002670804,0.000092227594,0.00009258963,0.00004638659,0.000056718574,0.0000065211707,0.00011514168,0.00007788528,0.00004671471],"category_scores_gemma":[0.000062023486,0.000090540256,0.00004943496,0.00013938536,0.00006284112,0.0000069070848,0.000042491243,0.000051502575,0.0000028118066],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004904532,0.0037407372,0.23201469,0.000120459204,0.0003026567,0.0001716942,0.005569227,0.00007333028,0.705121,0.000271022,0.0003721097,0.051752616],"study_design_scores_gemma":[0.0022045868,0.0015697494,0.028707797,0.000012230254,0.000105745385,0.00039975514,0.0025693967,0.0013270508,0.95958567,0.0011585423,0.001998704,0.00036077725],"about_ca_topic_score_codex":0.00017238034,"about_ca_topic_score_gemma":0.00003282164,"teacher_disagreement_score":0.25446466,"about_ca_system_score_codex":0.000009587656,"about_ca_system_score_gemma":0.0000287955,"threshold_uncertainty_score":0.36921245},"labels":[],"label_agreement":null},{"id":"W2081733255","doi":"10.1016/j.biologicals.2009.11.010","title":"Influence of bovine serum albumin on the secondary structure of interferon alpha 2b as determined by far UV circular dichroism spectropolarimetry","year":2009,"lang":"en","type":"article","venue":"Biologicals","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Health Canada","funders":"","keywords":"Circular dichroism; Protein secondary structure; Excipient; Bovine serum albumin; Chemistry; Protein tertiary structure; Alpha interferon; Albumin; Protein structure; Serum albumin; Alpha (finance); Chromatography; Interferon; Biochemistry; Immunology; Biology; Medicine; Surgery","score_opus":0.006941510629092174,"score_gpt":0.24706830781758232,"score_spread":0.24012679718849014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081733255","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965416,0.0020337298,0.00010945858,0.0005441087,0.000020030027,0.00028950558,0.0001945022,0.000009904096,0.0002571414],"genre_scores_gemma":[0.9984774,0.00012140199,0.00007942737,0.0011378794,0.000031132655,0.0000035761263,0.00008456616,0.000005275216,0.00005935011],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988573,0.00018345035,0.00033519906,0.00033781922,0.0001068999,0.00017929451],"domain_scores_gemma":[0.99907845,0.000035999663,0.00019803933,0.0005553437,0.00007887071,0.00005329374],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021764319,0.00016395438,0.00022919467,0.000022984035,0.000045505505,0.0000070953133,0.0003837692,0.00024500946,0.0001572715],"category_scores_gemma":[0.0004206498,0.00009992049,0.0001025687,0.00008818661,0.00024157294,0.0000035164437,0.00006503553,0.00015259717,0.0000038033959],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016106463,0.00008708848,0.0014193733,0.000010715101,0.000023183504,6.2415927e-7,0.000011335255,0.0000027424064,0.9949759,0.00040183426,0.00013273428,0.0027733522],"study_design_scores_gemma":[0.00021254731,0.002010267,0.08289477,0.000008714083,0.000007495904,0.0000045578945,0.000018860164,0.0000034870332,0.908211,0.0011293815,0.0053848233,0.00011410189],"about_ca_topic_score_codex":0.000018550109,"about_ca_topic_score_gemma":0.0000022038942,"teacher_disagreement_score":0.08676496,"about_ca_system_score_codex":0.000013192688,"about_ca_system_score_gemma":0.000042989748,"threshold_uncertainty_score":0.40746394},"labels":[],"label_agreement":null},{"id":"W2082099067","doi":"10.1021/bp0341904","title":"Inexpensive and Generic Affinity Purification of Recombinant Proteins Using a Family 2a CBM Fusion Tag","year":2004,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Recombinant DNA; Fusion protein; Chromatography; Chemistry; Affinity chromatography; Escherichia coli; Fusion; Diffusion; Biochemistry; Enzyme","score_opus":0.02372961078938232,"score_gpt":0.26467003426449975,"score_spread":0.24094042347511743,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082099067","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903304,0.003872724,0.00370428,0.0011177923,0.00009740046,0.0007957074,0.00000973282,0.00004898398,0.000022969785],"genre_scores_gemma":[0.980613,0.0004887297,0.018687222,0.00004211063,0.000022723374,0.00008583221,0.000033833363,0.00001396569,0.000012590226],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989157,0.00005690895,0.0002794337,0.00044799445,0.00009630403,0.00020369927],"domain_scores_gemma":[0.9990395,0.000003307745,0.00021860351,0.00054203026,0.00014830337,0.000048291437],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020655322,0.00015141489,0.00018379593,0.00009481909,0.00010671562,0.000010790656,0.0002030659,0.0005106057,0.0000018868875],"category_scores_gemma":[0.00012637579,0.00014202128,0.000045886154,0.00020439364,0.0005459472,0.0000062596155,0.0001732703,0.00012729925,0.000002073684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007490685,0.00021194924,0.0015333648,0.000040001618,0.00001911465,0.0000018795797,0.00003746208,0.000004954343,0.9845472,0.0016696418,0.000007315877,0.011852229],"study_design_scores_gemma":[0.0006985851,0.00041701927,0.011841858,0.000026203117,0.0000134282745,0.000027374612,0.00011765812,0.000051721352,0.98271763,0.0006879835,0.0032218653,0.00017867281],"about_ca_topic_score_codex":0.000046252077,"about_ca_topic_score_gemma":0.000013391587,"teacher_disagreement_score":0.0149829425,"about_ca_system_score_codex":0.000029539,"about_ca_system_score_gemma":0.00011320102,"threshold_uncertainty_score":0.57914597},"labels":[],"label_agreement":null},{"id":"W2085625264","doi":"10.1139/o03-061","title":"Inactivation and conformational changes of creatine kinase at low concentrations of hexafluoroisopropanol solutions","year":2003,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Enzyme; Circular dichroism; Chemistry; Substrate (aquarium); Enzyme assay; Creatine kinase; Denaturation (fissile materials); Fluorescence; Conformational change; Protein secondary structure; Biochemistry; Biophysics; Biology; Nuclear chemistry","score_opus":0.010373550426887304,"score_gpt":0.22282338086970643,"score_spread":0.21244983044281912,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085625264","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942155,0.002675524,0.0005047022,0.00007370617,0.00001748046,0.00012866319,0.00011334891,0.0000035244443,0.0022675751],"genre_scores_gemma":[0.9985823,0.0004554947,0.00034883968,0.00003009243,0.00001517093,0.000020019916,0.00032682152,0.0000028624354,0.00021839098],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994821,0.000042571784,0.00017647368,0.00016607976,0.00003367117,0.00009912429],"domain_scores_gemma":[0.99955845,0.000018187986,0.00013284512,0.00014607313,0.00010031238,0.000044125718],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117785145,0.000079152705,0.000104243525,0.000013906827,0.0000699542,0.0000025189436,0.00003871373,0.00013993982,0.00003769068],"category_scores_gemma":[0.00011293628,0.00007548415,0.000020562798,0.000038779453,0.00029591765,0.000002784621,0.000034013752,0.000032269705,3.070211e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037816182,0.000061356914,0.0028027033,0.00008704094,0.000010139187,3.646551e-8,0.000030551397,8.540423e-7,0.9943063,0.0020189586,0.000027665836,0.0006165381],"study_design_scores_gemma":[0.00037996745,0.000111264046,0.0012642165,0.000005653291,0.000007808937,0.000005062126,0.000090980066,0.00001917272,0.99253935,0.00010714425,0.005396221,0.00007319171],"about_ca_topic_score_codex":0.0000061178753,"about_ca_topic_score_gemma":0.0000036729498,"teacher_disagreement_score":0.005368555,"about_ca_system_score_codex":0.000008149027,"about_ca_system_score_gemma":0.00005685369,"threshold_uncertainty_score":0.30781546},"labels":[],"label_agreement":null},{"id":"W2086234132","doi":"10.1002/elps.201100611","title":"Applications of imaged capillary isoelectric focussing technique in development of biopharmaceutical glycoprotein‐based products","year":2012,"lang":"en","type":"article","venue":"Electrophoresis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Biopharmaceutical; Isoelectric focusing; Glycoprotein; Chromatography; Chemistry; Computational biology; Computer science; Biochemistry; Biology; Biotechnology","score_opus":0.010754079426141715,"score_gpt":0.2720123668013738,"score_spread":0.2612582873752321,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086234132","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8929204,0.0138671305,0.09047197,0.00017409392,0.000020382968,0.002060091,0.000008568786,0.000021624679,0.0004557594],"genre_scores_gemma":[0.9739864,0.00007670591,0.02527183,0.000022096492,0.000034323137,0.0005408145,0.00003337164,0.000013847659,0.000020596555],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988669,0.000106615655,0.0003670269,0.00023613538,0.00013879174,0.00028454416],"domain_scores_gemma":[0.9993318,0.000011720141,0.00012534829,0.00034319112,0.00012745454,0.000060510003],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005114081,0.000116560856,0.00015986306,0.00013362021,0.000045870336,0.0000032048058,0.0001579424,0.00011086792,0.000015588377],"category_scores_gemma":[0.00012159464,0.000112280126,0.000044437424,0.0005449658,0.00008592071,0.00000433237,0.000033247336,0.00010766415,0.0000017313687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011845813,0.00030327405,0.0023209092,0.000090313675,0.000012344408,1.08916076e-7,0.00003275969,5.8430726e-7,0.9807113,0.00006327293,0.000020200563,0.016326485],"study_design_scores_gemma":[0.00022960313,0.000065031505,0.0069758,0.000008142131,0.000007434037,0.000001898764,0.0000065514564,0.0000084095645,0.9838876,0.00003114787,0.008662355,0.00011600479],"about_ca_topic_score_codex":0.00001018916,"about_ca_topic_score_gemma":0.0000047681024,"teacher_disagreement_score":0.081066035,"about_ca_system_score_codex":0.000047836176,"about_ca_system_score_gemma":0.0003366587,"threshold_uncertainty_score":0.45786506},"labels":[],"label_agreement":null},{"id":"W2086885047","doi":"10.1021/cm048166c","title":"Properties of Human Serum Albumin Entrapped in Sol−Gel-Derived Silica Bearing Covalently Tethered Sugars","year":2005,"lang":"en","type":"article","venue":"Chemistry of Materials","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Covalent bond; Tetraethyl orthosilicate; Thermal stability; Chemistry; Human serum albumin; Ligand (biochemistry); Protein adsorption; Adsorption; Nanoparticle; Chemical engineering; Polymer chemistry; Biophysics; Organic chemistry; Materials science; Chromatography; Nanotechnology; Biochemistry","score_opus":0.019110751315442816,"score_gpt":0.2456013082864025,"score_spread":0.22649055697095968,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086885047","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99875283,0.0004633393,0.0000040891314,0.00013272674,0.00002222068,0.0002114309,0.000054972923,0.000009402033,0.0003490125],"genre_scores_gemma":[0.9992696,0.00003958772,0.00017490999,0.00001824239,0.00006311866,0.000031204992,0.000060785052,0.000013345854,0.00032922032],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892336,0.00005121004,0.00048021143,0.0002629531,0.00010472109,0.0001775272],"domain_scores_gemma":[0.99930733,0.000003824041,0.00019118749,0.0003832607,0.000072471164,0.00004192265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002925742,0.00013211407,0.0002553167,0.000013849997,0.000027421784,0.00001023379,0.00022189278,0.00015758419,0.00023508556],"category_scores_gemma":[0.000097484226,0.00012838504,0.000055153087,0.000029801327,0.00016997187,0.000004564291,0.000076942495,0.000042002324,0.0000021310075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011297659,0.00013889412,0.0006691415,0.00036177057,0.000019775609,2.4593743e-7,0.00013828096,0.000006347594,0.99826056,0.0000022028485,0.000021402297,0.00026843167],"study_design_scores_gemma":[0.0005893355,0.00003006004,0.0028680174,0.00005860043,0.0000063726957,0.0000016826351,0.000098384284,0.0000019170288,0.9956492,0.0000138322985,0.00055563496,0.0001269517],"about_ca_topic_score_codex":0.000028420243,"about_ca_topic_score_gemma":0.0000093273675,"teacher_disagreement_score":0.0026113193,"about_ca_system_score_codex":0.000016519502,"about_ca_system_score_gemma":0.00005220814,"threshold_uncertainty_score":0.523539},"labels":[],"label_agreement":null},{"id":"W2086966539","doi":"10.1021/ac7026222","title":"Assessment of the Three-Dimensional Structure of Recombinant Protein Therapeutics by NMR Fingerprinting:  Demonstration on Recombinant Human Granulocyte Macrophage-Colony Stimulation Factor","year":2008,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Carleton University; University of Ottawa; Health Canada","funders":"","keywords":"Recombinant DNA; Chemistry; Heteronuclear single quantum coherence spectroscopy; Stimulation; Escherichia coli; Granulocyte; Biochemistry; In vitro; Two-dimensional nuclear magnetic resonance spectroscopy; Stereochemistry; Immunology; Gene; Biology; Neuroscience","score_opus":0.019507066325242076,"score_gpt":0.28240030107897085,"score_spread":0.2628932347537288,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086966539","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987135,0.000066530265,0.0004031999,0.00015772968,0.000037951773,0.00032835,0.000039969993,0.000007142559,0.00024562204],"genre_scores_gemma":[0.999059,0.0000058866085,0.00030948917,0.000038762184,0.000021786584,0.0000095376645,0.000108417094,0.000012231367,0.00043488474],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99871904,0.00006361439,0.00043092333,0.00032886566,0.00029515894,0.0001623754],"domain_scores_gemma":[0.9989883,0.000023497589,0.00027199878,0.000493026,0.00016814469,0.000055069344],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012294437,0.00016497938,0.0002036179,0.000012358948,0.00014362861,0.0000070774913,0.00022018833,0.00022532881,0.00008197757],"category_scores_gemma":[0.000087874294,0.00012311907,0.00014424883,0.000105084684,0.00024481813,0.0000043853706,0.000062473926,0.00021903154,3.9488614e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004688849,0.0002553976,0.018771682,0.00005130183,0.00004381721,4.2912816e-7,0.0000072813755,0.000107224085,0.98021436,0.00010777726,0.00005458077,0.00033925308],"study_design_scores_gemma":[0.00045849386,0.00013960936,0.10523701,0.000027712747,0.000021973663,0.0000035657326,0.0000035787918,0.002372959,0.89097226,0.0003469725,0.00028641403,0.00012948028],"about_ca_topic_score_codex":0.000016599648,"about_ca_topic_score_gemma":0.000006231737,"teacher_disagreement_score":0.08924213,"about_ca_system_score_codex":0.000040083796,"about_ca_system_score_gemma":0.00013947819,"threshold_uncertainty_score":0.502065},"labels":[],"label_agreement":null},{"id":"W2087126225","doi":"10.1002/elps.200600300","title":"Dynamic unfolding of a regulatory subunit of cAMP‐dependent protein kinase by capillary electrophoresis: Impact of cAMP dissociation on protein stability","year":2006,"lang":"en","type":"article","venue":"Electrophoresis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Protein subunit; Dissociation (chemistry); cAMP receptor protein; Protein kinase A; Dissociation constant; Cooperativity; Capillary electrophoresis; Cooperative binding; Chromatography; Biophysics; Receptor; Analytical Chemistry (journal); Enzyme; Biochemistry; Physical chemistry; Biology","score_opus":0.0038791436061872435,"score_gpt":0.22476297205954773,"score_spread":0.2208838284533605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087126225","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938892,0.0040258085,0.00027014385,0.00004872207,0.000013242266,0.0013535682,0.00025151574,0.000016908989,0.00013088287],"genre_scores_gemma":[0.99904233,0.00009611968,0.00017393875,0.000004862696,0.00002298053,0.00016191386,0.00029010896,0.000038145263,0.00016959738],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997314,0.00040137002,0.00079421693,0.00055360486,0.00049353996,0.00044329307],"domain_scores_gemma":[0.9979245,0.000026294856,0.0007063893,0.00086958875,0.00038603958,0.000087190994],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006450365,0.00030845864,0.00047475117,0.00012870203,0.00008071799,0.000010469694,0.0003089198,0.0002853557,0.00006363512],"category_scores_gemma":[0.00029271268,0.00028741898,0.00033379384,0.00036172388,0.00019084051,0.000009871484,0.00005211814,0.00018594999,0.000001260067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010690884,0.00063327706,0.0024216431,0.0001419719,0.000114778304,0.0000012490931,0.00003950763,0.000034918503,0.99486285,0.00017847585,0.000131262,0.000370977],"study_design_scores_gemma":[0.00057749636,0.0014335936,0.028346885,0.000036143316,0.000032046864,0.0000016608446,0.000029540262,0.00005682367,0.9687276,0.00045561814,0.000060018145,0.000242614],"about_ca_topic_score_codex":0.0011263011,"about_ca_topic_score_gemma":0.00020953953,"teacher_disagreement_score":0.026135292,"about_ca_system_score_codex":0.0003514745,"about_ca_system_score_gemma":0.0004293334,"threshold_uncertainty_score":0.9999578},"labels":[],"label_agreement":null},{"id":"W2089133853","doi":"10.1016/s0731-7085(00)00419-2","title":"Reversed phase HPLC of Met58 oxidized rhIL-11: oxidation enhanced by plastic tubes","year":2000,"lang":"en","type":"article","venue":"Journal of Pharmaceutical and Biomedical Analysis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Chemistry; Polypropylene; Chromatography; Elution; Polystyrene; High-performance liquid chromatography; Residue (chemistry); Polymer; Organic chemistry","score_opus":0.010306815912589678,"score_gpt":0.3197925514424728,"score_spread":0.3094857355298831,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089133853","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98187274,0.0010191189,0.015983367,0.00090412964,0.000041575546,0.000068262816,0.000047228263,0.0000033641286,0.00006024227],"genre_scores_gemma":[0.99738026,0.0014067467,0.0006974303,0.00016168485,0.00009913194,0.000002394159,0.000080317994,0.000004573348,0.00016748038],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99849486,0.00016071131,0.0006355164,0.00020377497,0.00034618744,0.00015894607],"domain_scores_gemma":[0.999187,0.00006748743,0.00015180864,0.00012773254,0.00015335936,0.00031260858],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000575253,0.00012104035,0.0003713541,0.00012478743,0.000044595385,0.0000131880315,0.00015168797,0.00012886395,0.0014803561],"category_scores_gemma":[0.00026850967,0.000087025655,0.00026732648,0.00046804993,0.0002953225,0.000010516451,0.000023271881,0.00012824421,0.0000027056349],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006483495,0.0006262085,0.0001763142,0.000024646286,0.00060770387,0.0000018711239,0.000017192046,0.0000027394046,0.969896,0.000009782766,0.00058181613,0.027407384],"study_design_scores_gemma":[0.0032983164,0.00047435824,0.0005403482,0.000012239567,0.0012023269,0.000009047643,0.0000319728,0.0011711079,0.90218353,0.00005528116,0.09088012,0.0001413232],"about_ca_topic_score_codex":0.0000062114073,"about_ca_topic_score_gemma":0.0000015785789,"teacher_disagreement_score":0.0902983,"about_ca_system_score_codex":0.000011208076,"about_ca_system_score_gemma":0.00004920947,"threshold_uncertainty_score":0.99943244},"labels":[],"label_agreement":null},{"id":"W2090629864","doi":"10.1016/j.ab.2009.12.018","title":"Use of thermal melt curves to assess the quality of enzyme preparations","year":2009,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; University of Toronto; University of Washington","keywords":"Enzyme; Standard curve; Sodium dodecyl sulfate; Chemistry; Melting curve analysis; Biochemistry; Enzyme assay; Chromatography; Recombinant DNA; Protease; Melting temperature; Real-time polymerase chain reaction; Materials science; Gene","score_opus":0.08398272323500783,"score_gpt":0.37330608402173643,"score_spread":0.2893233607867286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090629864","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99419785,0.0005078162,0.0012529116,0.0021489428,0.000011053573,0.00017916149,0.00006922101,0.000006728264,0.0016263048],"genre_scores_gemma":[0.99837595,0.00004613736,0.0003646083,0.00062910526,0.00003460301,0.00000895581,0.00006353506,0.0000034542488,0.00047363306],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999001,0.00008340525,0.00037284824,0.0002372945,0.00018215875,0.00012327167],"domain_scores_gemma":[0.9988405,0.000057990543,0.00011131714,0.00069524534,0.0002151395,0.00007977191],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038074466,0.00009456834,0.00016128038,0.000010086741,0.00003382012,0.000009822378,0.0002397221,0.00010042346,0.00004174686],"category_scores_gemma":[0.001121928,0.00007002012,0.00012782983,0.00013242295,0.00014568891,0.000003781524,0.000049221955,0.000066798595,0.0000020091272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059140624,0.00015124153,0.0010301765,0.000041035866,0.00003031935,8.7745384e-8,0.000010984449,0.000019186715,0.99614656,0.0006369418,0.0013419386,0.0005324157],"study_design_scores_gemma":[0.00007307462,0.00006822902,0.019359047,0.00001602328,0.000019186622,6.5962956e-7,0.000017558476,0.00005847681,0.97832555,0.00005639308,0.001920053,0.00008577639],"about_ca_topic_score_codex":0.000014675672,"about_ca_topic_score_gemma":0.000003088907,"teacher_disagreement_score":0.01832887,"about_ca_system_score_codex":0.000007328676,"about_ca_system_score_gemma":0.000088266635,"threshold_uncertainty_score":0.28553376},"labels":[],"label_agreement":null},{"id":"W2090673341","doi":"10.1002/cjce.20485","title":"Theoritical analysis and simulation of five‐zone simulating moving bed for ternary mixture separation","year":2011,"lang":"en","type":"article","venue":"The Canadian Journal of Chemical Engineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Korea University","keywords":"Simulated moving bed; Ternary operation; Volumetric flow rate; Chromatography; Chemistry; Mass transfer; Separation (statistics); Flow (mathematics); Dispersion (optics); Mechanics; Analytical Chemistry (journal); Adsorption; Mathematics; Statistics; Physics; Computer science; Organic chemistry","score_opus":0.009268886239859445,"score_gpt":0.2381788431948415,"score_spread":0.22890995695498206,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090673341","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.873361,0.00027623572,0.12619907,0.00005109599,0.000020666264,0.000065091604,0.000009575075,0.0000013089027,0.00001595976],"genre_scores_gemma":[0.99685764,9.810897e-7,0.0030374832,0.00001743,0.00006605941,0.0000016414416,0.000008143521,0.000005200833,0.0000053910603],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9995809,0.000013612243,0.00019936195,0.00006665183,0.000049298716,0.000090134956],"domain_scores_gemma":[0.9995555,0.00005040423,0.00007627706,0.00009364833,0.000122216,0.00010193449],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024534922,0.000054476972,0.00010602662,0.000050443294,0.000029012153,0.000008478706,0.00008229378,0.00006700902,0.0000057797974],"category_scores_gemma":[0.0003882065,0.000043855733,0.00007580811,0.000075431286,0.00004000271,0.000005694412,0.0000073964447,0.00006993477,2.8870268e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009339579,0.000013158359,0.0021606677,0.000046317546,0.00027071085,0.00000136348,0.00056525064,0.20257537,0.79218096,0.00043683025,0.0000041152825,0.0016518711],"study_design_scores_gemma":[0.0002967964,0.00006198349,0.001813919,0.000017356879,0.00015643254,0.000007742738,0.000024686911,0.5218147,0.47528946,0.00027734519,0.00013830239,0.00010125345],"about_ca_topic_score_codex":0.00009874166,"about_ca_topic_score_gemma":0.00006127638,"teacher_disagreement_score":0.31923935,"about_ca_system_score_codex":0.000015578446,"about_ca_system_score_gemma":0.00005639941,"threshold_uncertainty_score":0.17883848},"labels":[],"label_agreement":null},{"id":"W2090804451","doi":"10.1016/j.chroma.2013.07.004","title":"Computational fluid dynamic simulation of axial and radial flow membrane chromatography: Mechanisms of non-ideality and validation of the zonal rate model","year":2013,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Computational fluid dynamics; Volumetric flow rate; Mechanics; Flow (mathematics); Chemistry; Scale (ratio); Membrane; Biological system; Chromatography; Physics","score_opus":0.006481924246347058,"score_gpt":0.23647845365304357,"score_spread":0.22999652940669651,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090804451","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8868096,0.00023766905,0.11252611,0.0000801827,0.00004626811,0.00023705242,0.000047511945,0.0000016030863,0.000013982493],"genre_scores_gemma":[0.9929526,0.000066943816,0.0069102915,0.000020935153,0.00001738173,0.000004038009,0.000019860627,0.000007042787,8.9684204e-7],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99878603,0.00013437381,0.000614804,0.0001336201,0.0002449783,0.000086217384],"domain_scores_gemma":[0.998628,0.000044234326,0.0006795491,0.00016475601,0.00042470076,0.00005873484],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049451273,0.000109974055,0.00025549004,0.00012095923,0.000047959817,0.000011383168,0.00012488091,0.00010322986,0.000009654263],"category_scores_gemma":[0.000057541718,0.000084818246,0.00020043566,0.00016674027,0.00024820818,0.000024424644,0.00003799344,0.000070674934,5.0110724e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014479246,0.000108409506,0.0027412472,0.00013791073,0.0001227104,9.6488684e-8,0.000107135296,0.07712929,0.91865176,0.00024033326,0.00000964091,0.00060668157],"study_design_scores_gemma":[0.0015143454,0.0002988538,0.114110865,0.000058137328,0.00006896441,0.00001847035,0.00004507436,0.46806517,0.40138605,0.014308836,0.0000070468946,0.00011817584],"about_ca_topic_score_codex":0.000015478545,"about_ca_topic_score_gemma":0.000002554771,"teacher_disagreement_score":0.5172657,"about_ca_system_score_codex":0.000004681763,"about_ca_system_score_gemma":0.00009573881,"threshold_uncertainty_score":0.34587878},"labels":[],"label_agreement":null},{"id":"W2091419533","doi":"10.1016/j.pep.2011.05.006","title":"A centrifugation-free high-throughput protein purification system using in-line microfluidization","year":2011,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Structural Genomics Consortium","funders":"Canadian Institutes of Health Research; Knut och Alice Wallenbergs Stiftelse; Wellcome Trust; Genome Canada","keywords":"Centrifugation; Chromatography; Chemistry; Limiting; Protein purification","score_opus":0.026650869294079147,"score_gpt":0.2434280386342902,"score_spread":0.21677716934021105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091419533","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92297417,0.0017669068,0.071731366,0.00020173256,0.00009506381,0.0026966806,0.00003755821,0.000080935686,0.00041560354],"genre_scores_gemma":[0.973433,0.00009692536,0.02519075,0.000031204952,0.000107515116,0.00063860684,0.0002797987,0.000033683067,0.00018852114],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977546,0.00033733714,0.0006319338,0.0007501933,0.00024365704,0.00028227645],"domain_scores_gemma":[0.9983113,0.0000069056887,0.0003588469,0.00095428753,0.00024445358,0.00012421868],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006739119,0.00025070933,0.0002040225,0.00015113899,0.00021282352,0.000052005806,0.0003150028,0.00026906774,0.000034469624],"category_scores_gemma":[0.00025898928,0.00024673642,0.000050626062,0.0002895773,0.000106872765,0.000050793486,0.000104559556,0.00014946445,0.000011179464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022263898,0.00019488063,0.00083844754,0.000147434,0.0000073256983,9.064249e-7,0.00024560036,0.0000092337505,0.99067307,0.0053196014,0.000026379714,0.0023144998],"study_design_scores_gemma":[0.0010632917,0.000092715825,0.005140995,0.0001806592,0.0000103921775,0.000008031847,0.00023917356,0.00079907733,0.98911566,0.0010424562,0.0020055398,0.00030202747],"about_ca_topic_score_codex":0.00015447596,"about_ca_topic_score_gemma":0.000011295176,"teacher_disagreement_score":0.050458845,"about_ca_system_score_codex":0.00007866534,"about_ca_system_score_gemma":0.00010211398,"threshold_uncertainty_score":0.9999985},"labels":[],"label_agreement":null},{"id":"W2097097625","doi":"10.1039/b604184c","title":"Structural modelling of metal ion binding to human haemopexin","year":2007,"lang":"en","type":"review","venue":"Natural Product Reports","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; University of British Columbia","funders":"","keywords":"Chemistry; Metal ions in aqueous solution; Biochemistry; Metal; Biophysics; Computational biology; Biology; Organic chemistry","score_opus":0.09174216223827125,"score_gpt":0.3696477854906132,"score_spread":0.27790562325234197,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097097625","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.019550756,0.978036,0.0000936994,0.0000140796255,0.0007581328,0.0012794762,0.000017204104,0.000021250597,0.00022939347],"genre_scores_gemma":[0.3253001,0.66615325,0.0028488152,0.000024298286,0.0011655908,0.00007293504,0.0019533057,0.000094422736,0.0023872778],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971908,0.00010478259,0.0010851005,0.000995123,0.00032090792,0.00030328773],"domain_scores_gemma":[0.9978202,0.000008234874,0.0007374456,0.0010839825,0.0002463756,0.00010377712],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009712098,0.00037384176,0.0008804551,0.00016827096,0.00010828517,0.000022015469,0.00024521537,0.00030546062,0.00001459485],"category_scores_gemma":[0.00028707983,0.00029556686,0.00042689816,0.00028827527,0.00007094224,0.0000064134592,0.00016383271,0.00038395557,0.0000032349242],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023085915,0.000044168293,0.00003576784,0.004916945,0.00022141915,0.00004791208,0.000035414192,0.00008286428,0.021181019,0.00006464583,0.00022593087,0.9731208],"study_design_scores_gemma":[0.000050626262,0.000070058486,0.000015842474,0.0006594914,0.00016331358,0.00040318986,0.0000039803876,0.0000047988406,0.035299852,0.000053964723,0.96276873,0.00050616724],"about_ca_topic_score_codex":0.00002758919,"about_ca_topic_score_gemma":0.0000071574696,"teacher_disagreement_score":0.97261465,"about_ca_system_score_codex":0.00005857885,"about_ca_system_score_gemma":0.00017232385,"threshold_uncertainty_score":0.99994963},"labels":[],"label_agreement":null},{"id":"W2098816642","doi":"10.3382/ps.2008-00485","title":"Effect of different concentrations of calcium chloride and potassium chloride on egg white proteins during isoelectric precipitation of ovomucin","year":2009,"lang":"en","type":"article","venue":"Poultry Science","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Ovalbumin; Lysozyme; Chemistry; Egg white; Ovotransferrin; Chromatography; Precipitation; Potassium; Isoelectric point; Calcium; Salt (chemistry); Sodium; Extraction (chemistry); Chloride; Food science; Biochemistry; Enzyme; Biology; Antigen","score_opus":0.006789994367019408,"score_gpt":0.2644952803937769,"score_spread":0.2577052860267575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098816642","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982223,0.000091659866,0.00078244286,0.00011548982,0.000041365063,0.00047061543,0.000013486951,0.000004919195,0.00025771948],"genre_scores_gemma":[0.9997886,0.000027132002,0.000085769905,0.000011758521,0.00001972965,0.000017788532,0.0000088396555,0.0000027365563,0.00003768994],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990416,0.000059717626,0.0002533287,0.00027259576,0.00021935817,0.00015337062],"domain_scores_gemma":[0.999319,0.000025066014,0.00018438399,0.00027121534,0.000139747,0.000060589988],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003954083,0.00009440764,0.00014783963,0.00007130351,0.000058535446,0.00000818255,0.00015824108,0.00005118695,0.0000028787665],"category_scores_gemma":[0.0004728563,0.00007624172,0.000039144183,0.00026613896,0.00022581495,0.000012735217,0.000021495396,0.000056188448,2.5100536e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028358377,0.000080203165,0.03315966,0.000056924986,0.000003328401,6.253844e-8,0.00012191868,0.00002887972,0.96461815,0.00022459532,7.1072293e-7,0.001422002],"study_design_scores_gemma":[0.00026173115,0.00078054756,0.32982022,0.00001560394,0.0000052040705,8.14237e-7,0.000019975676,0.00008681891,0.66892266,0.000036794834,0.0000037992545,0.00004579328],"about_ca_topic_score_codex":0.000009740335,"about_ca_topic_score_gemma":0.0000018486093,"teacher_disagreement_score":0.29666057,"about_ca_system_score_codex":0.000019163326,"about_ca_system_score_gemma":0.00007400769,"threshold_uncertainty_score":0.3109047},"labels":[],"label_agreement":null},{"id":"W2098930950","doi":"10.1002/bit.22362","title":"Integrated fragmentation of human IgG and purification of Fab using a reactant adsorptive membrane bioreactor separator system","year":2009,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Chromatography; Membrane; Bioreactor; Microporous material; Papain; Adsorption; Separator (oil production); Membrane bioreactor; Separation process; Packed bed; Elution; Organic chemistry; Biochemistry","score_opus":0.011609226606968984,"score_gpt":0.24524322085299652,"score_spread":0.23363399424602754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098930950","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927466,0.0011334294,0.0057582553,0.000076249096,0.000021026533,0.000191244,0.00002649181,0.000031110096,0.00001560565],"genre_scores_gemma":[0.9976623,0.0001267721,0.0021461078,0.0000049492587,0.000010154052,0.000004722001,0.00003714612,0.0000049626246,0.0000028681052],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99941504,0.000019130859,0.00022912183,0.00020326948,0.00004369343,0.000089726986],"domain_scores_gemma":[0.9996094,0.000004125583,0.0001211082,0.00018220035,0.00005687542,0.000026278047],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000122322,0.00009992155,0.00015172691,0.00009892378,0.000031149844,0.0000042657007,0.00006208922,0.0002661474,8.1027036e-7],"category_scores_gemma":[0.000028198916,0.00009181216,0.000022703796,0.00012337843,0.0001130984,0.000007212625,0.000018638128,0.00006859479,9.179357e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033102522,0.000028252152,0.00025031803,0.00006493085,0.000023228175,2.6869418e-7,0.000034152774,0.0000058659666,0.995086,0.0024201425,4.938354e-7,0.0020532007],"study_design_scores_gemma":[0.00023641127,0.00023897813,0.0033382447,0.000040770443,0.00001876558,0.000011186162,0.00023830478,0.0010478387,0.99461234,0.000016669686,0.00011321032,0.00008729528],"about_ca_topic_score_codex":0.000016329463,"about_ca_topic_score_gemma":0.000001916361,"teacher_disagreement_score":0.00491573,"about_ca_system_score_codex":0.000014504022,"about_ca_system_score_gemma":0.000016586118,"threshold_uncertainty_score":0.37439913},"labels":[],"label_agreement":null},{"id":"W2098990266","doi":"10.1186/1475-2859-10-51","title":"Overexpression and purification of U24 from human herpesvirus type-6 in E. coli: unconventional use of oxidizing environments with a maltose binding protein-hexahistine dual tag to enhance membrane protein yield","year":2011,"lang":"en","type":"article","venue":"Microbial Cell Factories","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Michael Smith Health Research BC","keywords":"Periplasmic space; Maltose-binding protein; Biochemistry; Fusion protein; Cytoplasm; Biology; Membrane protein; Chemistry; Biophysics; Cell biology; Membrane; Recombinant DNA; Escherichia coli; Gene","score_opus":0.027673881571760442,"score_gpt":0.23562229461322318,"score_spread":0.20794841304146272,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098990266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99869907,0.00007690256,0.00029188808,0.000009407067,0.000021452428,0.0007218944,0.00013568654,0.0000042830425,0.000039400857],"genre_scores_gemma":[0.9942895,0.00000963479,0.004916071,0.0000071075765,0.000017306746,0.00004515263,0.00012835364,0.000013085585,0.00057375233],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990655,0.00006688464,0.00030618772,0.00032481004,0.000108143926,0.00012845894],"domain_scores_gemma":[0.9994442,0.000008759046,0.00020263497,0.0002482114,0.00004616303,0.00005004884],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000096293734,0.00013378393,0.00016301448,0.000043387023,0.000048497983,0.000011234802,0.0000860441,0.00011435168,0.000096200114],"category_scores_gemma":[0.000063564024,0.00012610914,0.000024374269,0.00007819474,0.00011765768,0.000017748143,0.00007019555,0.000077499586,0.000002142145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00059185585,0.00020319223,0.0024084859,0.000073861615,0.0000118248445,5.6921573e-7,0.000388401,0.0000014084817,0.9961992,0.000035556466,0.000007342267,0.000078284356],"study_design_scores_gemma":[0.00028078532,0.00024976028,0.0074783494,0.00012601582,0.000006031856,3.3089094e-7,0.000054531953,4.612341e-7,0.989255,0.000018906569,0.0023968497,0.00013297456],"about_ca_topic_score_codex":0.00044066084,"about_ca_topic_score_gemma":0.00013349789,"teacher_disagreement_score":0.0069442154,"about_ca_system_score_codex":0.000023016573,"about_ca_system_score_gemma":0.000041770807,"threshold_uncertainty_score":0.51425815},"labels":[],"label_agreement":null},{"id":"W2101883797","doi":"10.1002/bit.25122","title":"Improved isoelectric focusing chromatography on strong anion exchange media via a new model that custom designs mobile phases using simple buffers","year":2013,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chromatofocusing; Elution; Chemistry; Chromatography; Isoelectric point; Isoelectric focusing; Ion exchange; Immobilized pH gradient; Ion chromatography; Mass spectrometry; Ion; Analytical Chemistry (journal); Organic chemistry","score_opus":0.024388103983720114,"score_gpt":0.2414828171882028,"score_spread":0.2170947132044827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101883797","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7072738,0.0025482306,0.2895176,0.000080339945,0.000047211022,0.00040947032,0.000009238444,0.00010580319,0.0000083163995],"genre_scores_gemma":[0.99322486,0.00038057982,0.0061533586,0.000047098918,0.00006815038,0.00005970442,0.00003260935,0.000024204795,0.00000943285],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989638,0.000018771669,0.00016755838,0.0004237524,0.000071001086,0.0003551452],"domain_scores_gemma":[0.9994552,0.000012573903,0.00006658112,0.00033164967,0.00002905468,0.00010495141],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009209783,0.00022690321,0.00017588196,0.00020942383,0.000115542825,0.000030177034,0.00015230557,0.00046403776,0.000015015198],"category_scores_gemma":[0.000029228773,0.00021415383,0.000066018154,0.00021677099,0.000099524106,0.00001610909,0.0000735804,0.00016898166,0.0000014712149],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020230973,0.000038064787,0.00015488951,0.000020707861,0.000032203232,4.8171745e-7,0.000023507953,0.00043098314,0.9745533,0.00005390972,0.000029568595,0.024642183],"study_design_scores_gemma":[0.00042018108,0.0002779788,0.00012771977,0.000012468614,0.000019815969,0.0000144354135,0.00005520275,0.15159024,0.84658974,0.00013251306,0.00048779338,0.00027192055],"about_ca_topic_score_codex":0.00006358407,"about_ca_topic_score_gemma":0.000010738239,"teacher_disagreement_score":0.28595108,"about_ca_system_score_codex":0.000026483347,"about_ca_system_score_gemma":0.000036166566,"threshold_uncertainty_score":0.87329394},"labels":[],"label_agreement":null},{"id":"W2105292800","doi":"10.51847/2qd3ki0","title":"10.51847/2Qd3KI0","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Jacobs University","keywords":"Isoelectric point; Chromatography; Raw material; Electrophoresis; Proteome; Chemistry; Ion exchange; Protein purification; Ion chromatography; Analytical Chemistry (journal); Ion; Biochemistry; Enzyme; Organic chemistry","score_opus":0.005074899221239945,"score_gpt":0.19267182152855647,"score_spread":0.18759692230731653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2105292800","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009782223,0.00018779405,0.000008442672,0.00029419,0.0000015935191,0.00016443525,0.000015886286,0.00002538642,0.9895201],"genre_scores_gemma":[0.011173087,0.0000012105527,0.00015597297,0.0001238919,0.000072410985,0.000025138985,0.000052310657,0.000008806274,0.98838717],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994826,0.000029925786,0.000094621915,0.00020400953,0.00006175045,0.00012714785],"domain_scores_gemma":[0.99952817,0.0000029371695,0.00001202836,0.00034036313,0.00003192213,0.00008459196],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00009898657,0.0000697722,0.000059932674,0.000012003589,0.000038922193,0.000012224838,0.0001331612,0.000060780952,0.93643415],"category_scores_gemma":[0.00003655248,0.000068781585,0.00003856109,0.000054253593,0.000024837522,0.0000012742094,0.000023442886,0.000030186457,0.80912346],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009592298,0.000049134156,0.0000012437805,0.0000027208544,0.000008906208,4.2987108e-7,0.0000033473048,0.000012649935,0.021897672,0.0000024611675,0.009133908,0.9687916],"study_design_scores_gemma":[0.00011380473,0.00009790171,0.00017951429,0.000001271695,0.0000026118169,0.0000021732883,2.9539603e-7,0.000015086447,0.0057514063,0.0000026385753,0.99374056,0.00009275309],"about_ca_topic_score_codex":0.0000037805667,"about_ca_topic_score_gemma":1.276743e-7,"teacher_disagreement_score":0.9846066,"about_ca_system_score_codex":0.000006173818,"about_ca_system_score_gemma":0.000022323524,"threshold_uncertainty_score":0.28048316},"labels":[],"label_agreement":null},{"id":"W2106601030","doi":"10.1002/jps.23746","title":"Utilizing Dynamic Light Scattering as a Process Analytical Technology for Protein Folding and Aggregation Monitoring in Vaccine Manufacturing","year":2013,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"Sanofi Pasteur; Agilent Technologies","keywords":"Dynamic light scattering; Process analytical technology; Protein aggregation; Size-exclusion chromatography; Solubilization; Folding (DSP implementation); Protein folding; Aggregate (composite); Manufacturing process; Light scattering; Characterization (materials science); Chemistry; Chromatography; Scattering; Materials science; Chemical engineering; Nanotechnology; Optics; Biochemistry; Physics; Engineering; Nanoparticle","score_opus":0.026028296578203117,"score_gpt":0.3689860340494774,"score_spread":0.3429577374712743,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106601030","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99435323,0.0010751248,0.0008594086,0.0032680433,0.000053529187,0.00032802497,3.439601e-7,0.000004825832,0.000057440266],"genre_scores_gemma":[0.9979186,0.00007830554,0.0018680292,0.000029584704,0.00005783486,0.00003344771,2.1483548e-7,0.0000043827704,0.000009623286],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991002,0.000029229037,0.00031027655,0.0002022602,0.00014386945,0.00021415066],"domain_scores_gemma":[0.99961346,0.00001691791,0.00012762664,0.0000612667,0.00009079704,0.00008994463],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006606311,0.000083514286,0.00012592957,0.00014835996,0.00009993972,0.0000600532,0.00018709037,0.000074154916,0.000010629331],"category_scores_gemma":[0.00028914885,0.00006565247,0.000035476274,0.00016035547,0.000094492454,0.00003870347,0.000049242077,0.00013383807,7.271716e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047455815,0.000042097774,0.014491053,0.00006233784,0.000010315964,0.0000014557709,0.000036794772,0.00003742768,0.92998636,0.00011962026,0.0000012765261,0.05516382],"study_design_scores_gemma":[0.0005291615,0.00025078488,0.0054231035,0.000107822794,0.00000936943,0.000049059618,0.0003946598,0.005195229,0.98494893,0.0025423258,0.0004470197,0.00010250541],"about_ca_topic_score_codex":0.0000023524915,"about_ca_topic_score_gemma":0.0000015185573,"teacher_disagreement_score":0.055061314,"about_ca_system_score_codex":0.0000274666,"about_ca_system_score_gemma":0.000050871713,"threshold_uncertainty_score":0.26772302},"labels":[],"label_agreement":null},{"id":"W2107459973","doi":"10.1007/s10985-010-9189-2","title":"Destructive weighted Poisson cure rate models","year":2010,"lang":"en","type":"article","venue":"Lifetime Data Analysis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Poisson distribution; Event (particle physics); Interpretation (philosophy); Poisson process; Econometrics; Statistics; Computer science; Cure rate; Distribution (mathematics); Dispersion (optics); Mathematics; Medicine; Mathematical analysis","score_opus":0.01649477260442236,"score_gpt":0.2771454930761183,"score_spread":0.26065072047169596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2107459973","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85802436,0.0005996628,0.1323448,0.0013864416,0.00016999285,0.00038867394,0.0027395166,0.00006726282,0.0042793155],"genre_scores_gemma":[0.98125494,0.000076450626,0.006071293,0.00015840288,0.0001335757,0.000015170498,0.011529246,0.00001204436,0.0007489085],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986957,0.00011301322,0.00021855517,0.0006666409,0.00012482997,0.00018127912],"domain_scores_gemma":[0.9973483,0.000013494559,0.00010065011,0.0022967616,0.00012112853,0.000119678785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045754612,0.00013931101,0.00019098476,0.000084944375,0.00009382206,0.00004430047,0.00065756845,0.00016865133,0.00032881726],"category_scores_gemma":[0.00013347408,0.0001266275,0.00011598444,0.00044472484,0.00009255605,0.000017830893,0.0002739694,0.00016174377,0.000035326982],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021669654,0.0003053208,0.015344533,0.000017752716,0.0028394049,0.0000045315014,0.00007888432,0.00036289496,0.95816386,0.002906827,0.005802311,0.013957004],"study_design_scores_gemma":[0.0016921923,0.00014925422,0.074340835,0.000006825154,0.0037686029,0.000014370967,0.000163439,0.29211542,0.29295298,0.007654829,0.3254322,0.001709031],"about_ca_topic_score_codex":0.00007172015,"about_ca_topic_score_gemma":0.00029138988,"teacher_disagreement_score":0.66521084,"about_ca_system_score_codex":0.000004519961,"about_ca_system_score_gemma":0.000055236862,"threshold_uncertainty_score":0.51637197},"labels":[],"label_agreement":null},{"id":"W2108620598","doi":"10.1002/bit.20416","title":"Separation of monoclonal antibody alemtuzumab monomer and dimers using ultrafiltration","year":2005,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Diafiltration; Ultrafiltration (renal); Membrane; Monomer; Chromatography; Chemistry; Polyvinylidene fluoride; Monoclonal antibody; Dimer; Yield (engineering); Separation process; Selectivity; Membrane technology; Chemical engineering; Microfiltration; Polymer; Materials science; Organic chemistry; Biochemistry; Antibody","score_opus":0.009398072234904907,"score_gpt":0.27320728079302775,"score_spread":0.26380920855812284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108620598","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97386134,0.0022312463,0.023451926,0.00028552426,0.000023126317,0.00009685769,0.0000068594863,0.000020036083,0.00002305968],"genre_scores_gemma":[0.9933517,0.00044873127,0.006111246,0.000014945183,0.00003080216,0.0000035280225,0.0000251743,0.0000049826026,0.0000089048235],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995615,0.000008701412,0.00013160963,0.00017480917,0.00003278844,0.00009060839],"domain_scores_gemma":[0.99979323,0.000003393902,0.00003986667,0.000119337885,0.000020527907,0.000023619566],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000086521504,0.00007713323,0.00008003809,0.00005515874,0.000037871738,0.0000053382396,0.000040365165,0.00022915466,0.0000025446],"category_scores_gemma":[0.000018466037,0.0000773112,0.000016620565,0.000055750195,0.00010659249,0.00000728953,0.000024330597,0.000061752326,3.2471152e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001512212,0.000013097136,0.001628496,0.000011850695,0.000017728873,9.5130254e-8,0.000014456895,0.00025804396,0.9917931,0.00058929564,0.0000014259958,0.0056572757],"study_design_scores_gemma":[0.00019508462,0.00007988211,0.0066500944,0.0000054743446,0.000010650506,0.000019782596,0.000027658589,0.012755279,0.9773459,0.000018861963,0.0027871204,0.000104225495],"about_ca_topic_score_codex":0.0000066407924,"about_ca_topic_score_gemma":0.000003655061,"teacher_disagreement_score":0.019490322,"about_ca_system_score_codex":0.00000658109,"about_ca_system_score_gemma":0.000013160827,"threshold_uncertainty_score":0.3152659},"labels":[],"label_agreement":null},{"id":"W2120786830","doi":"10.1016/j.biologicals.2005.06.007","title":"The effect of solvent environment on the conformation and stability of human polyclonal IgG in solution","year":2005,"lang":"en","type":"article","venue":"Biologicals","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Prairie Oat Growers Association; Agence Nationale pour la Gestion des Déchets Radioactifs; Hungarian Scientific Research Fund; Teva Pharmaceutical Industries","keywords":"Sorbitol; Chemistry; Conformational change; Denaturation (fissile materials); Maltose; Monomer; Thermal stability; Solvent; Sucrose; Biophysics; Chromatography; Organic chemistry; Biochemistry; Polymer; Nuclear chemistry","score_opus":0.0167142682739987,"score_gpt":0.25720191343629795,"score_spread":0.24048764516229926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120786830","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981033,0.00064342766,0.00007384941,0.00057075726,0.0000070329716,0.00031525068,0.000010955792,0.0000014618618,0.0002739582],"genre_scores_gemma":[0.9997539,0.00012783543,0.000017949102,0.00002957293,0.000011841083,0.00003376704,0.000016604208,9.65949e-7,0.000007586538],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993426,0.00022844023,0.00020025493,0.00010119194,0.000056286462,0.00007118766],"domain_scores_gemma":[0.99961746,0.000083252446,0.00009019248,0.00018717472,0.000008932283,0.000013012517],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001025275,0.000051747782,0.00007532738,0.000005687581,0.000055784887,0.0000021852563,0.000077035285,0.00006269175,0.000026529575],"category_scores_gemma":[0.00014379868,0.000023891303,0.00003363208,0.000014455207,0.00022678444,0.0000013076312,0.000038717077,0.000039177005,0.0000013522205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016596571,0.000056995195,0.017667156,0.000008455528,0.0000065545482,1.07199005e-8,0.000025932155,0.0000046114583,0.9713476,0.0010760975,0.000022048378,0.009618603],"study_design_scores_gemma":[0.00021191243,0.00078712654,0.1376423,0.0000031307818,0.000002000447,2.1208979e-7,0.000021420914,0.000054475353,0.8578803,0.00011756877,0.0032450145,0.000034550158],"about_ca_topic_score_codex":0.000006162046,"about_ca_topic_score_gemma":0.000008176991,"teacher_disagreement_score":0.119975135,"about_ca_system_score_codex":0.00001098349,"about_ca_system_score_gemma":0.000004742093,"threshold_uncertainty_score":0.09742591},"labels":[],"label_agreement":null},{"id":"W2121302417","doi":"10.1128/aem.68.7.3261-3269.2002","title":"Functional Production and Characterization of a Fibrin-Specific Single-Chain Antibody Fragment from<i>Bacillus subtilis</i>: Effects of Molecular Chaperones and a Wall-Bound Protease on Antibody Fragment Production","year":2002,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":200,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Bacillus subtilis; Protease; Monoclonal antibody; Antibody; Biochemistry; Biology; Extracellular; Chaperone (clinical); Chemistry; Molecular biology; Bacteria; Enzyme; Immunology","score_opus":0.0061965603245139255,"score_gpt":0.17746687035900532,"score_spread":0.1712703100344914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121302417","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996497,0.0017325555,0.00043462036,0.00020949598,0.00009381218,0.00094335264,0.00006868804,0.0000070788537,0.000013421428],"genre_scores_gemma":[0.99619246,0.00232721,0.00012882127,0.00005992416,0.000054721815,0.00006559107,0.0011190358,0.000013778908,0.000038435],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988844,0.000067525616,0.000251188,0.0005893371,0.00006402403,0.00014353117],"domain_scores_gemma":[0.99954396,0.000009684336,0.0001572404,0.00023016002,0.000009860671,0.000049083857],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000919714,0.00018688409,0.00020535704,0.000060174683,0.000075262265,0.000007786112,0.000039792976,0.00014068348,0.000023819255],"category_scores_gemma":[0.000011994166,0.00017865589,0.000028817056,0.000045617413,0.00037628174,0.000008432355,0.000068992,0.000067784196,0.0000022443764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019604084,0.00044201693,0.0022296412,0.00009225041,0.000044987126,5.486418e-7,0.00013895053,0.000004926839,0.99282163,0.000042119937,0.0000072047633,0.003979682],"study_design_scores_gemma":[0.00053212314,0.00043694556,0.04623545,0.00002641369,0.000019292238,0.000016558275,0.00004572223,0.00000966143,0.9510084,0.000033457436,0.0014794348,0.00015656438],"about_ca_topic_score_codex":0.0000049599944,"about_ca_topic_score_gemma":7.633574e-7,"teacher_disagreement_score":0.04400581,"about_ca_system_score_codex":0.000016591355,"about_ca_system_score_gemma":0.0000034914642,"threshold_uncertainty_score":0.72853756},"labels":[],"label_agreement":null},{"id":"W2133262715","doi":"10.1128/jcm.00892-09","title":"Identification of Performance Problems in a Commercial Human Immunodeficiency Virus Type 1 Enzyme Immunoassay by Multiuser External Quality Control Monitoring and Real-Time Data Analysis","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Microbiology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Saskatchewan Health; St. Paul's Hospital; Provincial Laboratory of Public Health; Dr. Georges-L.-Dumont University Hospital Centre; Public Health Agency of Canada","funders":"Abbott Diagnostics; Public Health Agency; Public Health Agency of Canada","keywords":"Christian ministry; Human immunodeficiency virus (HIV); Immunoassay; External quality assessment; Computer science; Medicine; Virology; Immunology; Pathology","score_opus":0.04789399914028599,"score_gpt":0.3958223223993967,"score_spread":0.3479283232591107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133262715","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961407,0.002049975,0.0013712565,0.00009686351,0.00011367058,0.00013040747,0.000080159494,0.0000022100212,0.0000147422425],"genre_scores_gemma":[0.99810153,0.0014050774,0.00027142832,0.000031487685,0.00007302174,0.0000011106271,0.00008229791,0.000004307666,0.000029715224],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99698645,0.0006149554,0.0019002588,0.00028524527,0.000062468585,0.00015061775],"domain_scores_gemma":[0.997872,0.00010676216,0.0011788553,0.00053836755,0.00025727262,0.000046750585],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004436497,0.00010853806,0.0005440323,0.00007867689,0.000047832735,0.00001361608,0.0004800446,0.00022354905,0.000010043312],"category_scores_gemma":[0.00060861936,0.00009275925,0.00012591101,0.00014851081,0.0001813949,0.000019329265,0.00007291178,0.00024081909,0.0000012617327],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033564636,0.00034153968,0.12824297,0.000007524989,0.00009498921,2.0968812e-7,0.000020023284,0.000021504042,0.86776555,0.000004420906,0.00001916786,0.0031464666],"study_design_scores_gemma":[0.0018083107,0.00077175937,0.90489036,0.000022502165,0.00011512702,0.000010018497,0.000014001398,0.00012873996,0.09131677,0.000029986692,0.00076027145,0.00013216089],"about_ca_topic_score_codex":0.000058362813,"about_ca_topic_score_gemma":0.000014022732,"teacher_disagreement_score":0.7766474,"about_ca_system_score_codex":0.00001533328,"about_ca_system_score_gemma":0.000065311986,"threshold_uncertainty_score":0.37826124},"labels":[],"label_agreement":null},{"id":"W2133776580","doi":"10.1139/w99-123","title":"Serogroups of the beer spoilage bacterium <i>Megasphaera cerevisiae</i> correlate with the molecular weight of the major EDTA-extractable surface protein","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Microbiology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Polyclonal antibodies; Bacteria; Microbiology; Ethylenediaminetetraacetic acid; Chemistry; Monoclonal antibody; Gel electrophoresis; Antigen; Antigenicity; Biology; Antibody; Biochemistry; Chelation","score_opus":0.0028360995918882167,"score_gpt":0.16666051221617298,"score_spread":0.16382441262428477,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133776580","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915361,0.0040316465,0.000047211615,0.003274417,0.00012927713,0.00041386997,0.000113892835,0.0000010460622,0.000452587],"genre_scores_gemma":[0.99785435,0.000029727165,0.000121643796,0.0005029701,0.00004170353,0.0000037430138,0.000009773742,0.00001520769,0.0014208652],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987317,0.0003536338,0.00040003815,0.00017282536,0.000064497865,0.00027734975],"domain_scores_gemma":[0.99862915,0.000014400233,0.00041285783,0.0005885905,0.00023776625,0.00011722445],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045714807,0.00015421909,0.00023824218,0.000020085497,0.0001293413,0.0000126896375,0.00076050055,0.00017238675,0.00030248114],"category_scores_gemma":[0.000042251293,0.00007644711,0.00019091743,0.00016187089,0.0005805438,0.000006774745,0.00003077936,0.00028835604,0.0000028485504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000103086386,0.000024838808,0.0021016211,0.000017625685,0.00008791789,0.0000040590458,0.00007883285,0.00007944365,0.9960983,0.0000779179,0.0009273976,0.00039898217],"study_design_scores_gemma":[0.00055856496,0.00018957851,0.0060935994,0.00005447277,0.00005988863,0.0003609697,0.00004285255,0.0000017616794,0.7412547,0.000027078999,0.2512349,0.00012169297],"about_ca_topic_score_codex":0.0004884499,"about_ca_topic_score_gemma":0.0028019021,"teacher_disagreement_score":0.25484362,"about_ca_system_score_codex":0.000030642706,"about_ca_system_score_gemma":0.0007940965,"threshold_uncertainty_score":0.33119562},"labels":[],"label_agreement":null},{"id":"W2135818676","doi":"10.1002/btpr.2140","title":"Intrinsic fluorescence‐based <i>at situ</i> soft sensor for monitoring monoclonal antibody aggregation","year":2015,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Partial least squares regression; Chemistry; Fluorescence; Protein aggregation; Monoclonal antibody; Fluorescence spectroscopy; In situ; Biological system; Chromatography; Monomer; Least-squares function approximation; Analytical Chemistry (journal); Biophysics; Antibody; Biochemistry; Computer science; Polymer; Statistics; Biology; Mathematics; Machine learning","score_opus":0.028247090247388636,"score_gpt":0.3055829523662631,"score_spread":0.27733586211887445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135818676","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98081934,0.002918848,0.011943958,0.0027975324,0.00035730345,0.00090221415,0.0000414896,0.00018093515,0.000038355032],"genre_scores_gemma":[0.97716427,0.00004280204,0.021974612,0.000048508227,0.0001942772,0.00022151605,0.00023672901,0.000021848036,0.00009542008],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987623,0.00004913527,0.00023107673,0.0005058346,0.00013745516,0.00031421773],"domain_scores_gemma":[0.9989708,0.000012723678,0.00013255008,0.00053928833,0.00024148224,0.0001031652],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029748914,0.00017535793,0.0001583988,0.00007655952,0.00013230366,0.000021989767,0.0002802589,0.00055822136,0.0000024793117],"category_scores_gemma":[0.00032234762,0.00017190343,0.0000777389,0.0001389821,0.00035021477,0.0000058646115,0.00012942581,0.00011455033,0.0000134125285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044346976,0.00016309117,0.034207545,0.00004183015,0.00003369056,0.000003473997,0.000018846,0.000009792782,0.8752395,0.00029443548,0.00027147727,0.08927289],"study_design_scores_gemma":[0.0009486077,0.00031513945,0.0015167019,0.000013122629,0.000012129022,0.000010911445,0.00003583573,0.0002821408,0.9448463,0.0001393853,0.05167993,0.00019983109],"about_ca_topic_score_codex":0.0000028855607,"about_ca_topic_score_gemma":0.0000034766958,"teacher_disagreement_score":0.089073054,"about_ca_system_score_codex":0.000062722414,"about_ca_system_score_gemma":0.00012422186,"threshold_uncertainty_score":0.7010019},"labels":[],"label_agreement":null},{"id":"W2137266621","doi":"10.1002/bit.25217","title":"Zonal rate model for axial and radial flow membrane chromatography, part II: Model‐based scale‐up","year":2014,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chromatography; Scale (ratio); Volumetric flow rate; Flow (mathematics); Chemistry; Membrane; Mechanics; Physics; Biochemistry","score_opus":0.008738494938869985,"score_gpt":0.2086168365040332,"score_spread":0.1998783415651632,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137266621","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5341806,0.0005050723,0.46405777,0.000824519,0.00008068113,0.00021217664,0.000056900422,0.00007076356,0.000011545859],"genre_scores_gemma":[0.9822777,0.00017592497,0.017154967,0.000115953786,0.00007359593,0.000070456,0.000069248366,0.000015094009,0.00004706648],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9991722,0.000014537895,0.00015952016,0.00038007429,0.000041745334,0.00023192198],"domain_scores_gemma":[0.9996047,0.000010097645,0.00003393118,0.00025040132,0.000028551762,0.00007228929],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023747045,0.00016307419,0.00015917807,0.00007782301,0.00014969567,0.00001376007,0.000107903696,0.00044735853,0.0000015706651],"category_scores_gemma":[0.00005023725,0.00015705492,0.000058054888,0.00006265267,0.0002061837,0.0000048776346,0.000067323745,0.000101386206,2.775588e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015980803,0.00004065777,0.000105529565,0.00008895463,0.000038335387,1.5453244e-7,0.000018453642,0.010945683,0.97640914,0.0024707566,0.000075583936,0.0096469745],"study_design_scores_gemma":[0.00061906455,0.00012051017,0.000053400323,0.0000061440783,0.000012697794,0.0000036846807,0.0000024698043,0.7039144,0.29089975,0.00020945218,0.004009403,0.00014903561],"about_ca_topic_score_codex":0.0000012610651,"about_ca_topic_score_gemma":0.000008515076,"teacher_disagreement_score":0.6929687,"about_ca_system_score_codex":0.0000045621814,"about_ca_system_score_gemma":0.000027141601,"threshold_uncertainty_score":0.6404514},"labels":[],"label_agreement":null},{"id":"W2141224788","doi":"10.1002/cjce.22336","title":"Simulated moving bed reactor for <i>p‐</i>xylene production: Optimal particle size","year":2015,"lang":"en","type":"article","venue":"The Canadian Journal of Chemical Engineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Ministerio de Economía y Competitividad","keywords":"Simulated moving bed; Raffinate; Particle (ecology); Isomerization; Particle size; Work (physics); Materials science; Yield (engineering); Adsorption; Pressure drop; Chemistry; Xylene; Catalysis; Chemical engineering; Chromatography; Process engineering; Analytical Chemistry (journal); Mechanics; Thermodynamics; Composite material; Organic chemistry; Extraction (chemistry); Physics; Physical chemistry; Engineering","score_opus":0.015370507589476402,"score_gpt":0.22080479469683242,"score_spread":0.20543428710735603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141224788","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99634415,0.00063404813,0.0011114723,0.0015890008,0.00018252352,0.000114616996,0.000005047286,0.000004810175,0.000014345029],"genre_scores_gemma":[0.9980198,0.0000011620284,0.0014936188,0.000062500134,0.0003674072,0.000003810485,0.00000344497,0.000011425427,0.000036798523],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994648,0.000012175752,0.00018817405,0.000088464054,0.0000761637,0.00017024206],"domain_scores_gemma":[0.9992078,0.000024053288,0.00006070436,0.00016147578,0.00022976575,0.00031622325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038878885,0.00006953055,0.00008834778,0.000012419406,0.000029527027,0.000022511831,0.00015706131,0.000062006366,0.0000047753633],"category_scores_gemma":[0.0021488245,0.00005542803,0.000059810016,0.000059673708,0.000037571113,0.0000065037157,0.000009195985,0.00010296131,5.2877067e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058656584,0.000007829451,0.000092818496,0.000008117598,0.00002780979,0.0000013262718,0.00009669972,0.017138677,0.9818802,0.000041862862,0.0003942723,0.000251737],"study_design_scores_gemma":[0.0003249659,0.000053531163,0.000036747035,0.000008991355,0.000012647933,0.00003623561,0.000014830678,0.0038504864,0.9834852,0.000028473203,0.01206807,0.00007978477],"about_ca_topic_score_codex":0.000065764616,"about_ca_topic_score_gemma":0.000029982517,"teacher_disagreement_score":0.013288191,"about_ca_system_score_codex":0.00006111902,"about_ca_system_score_gemma":0.00033603012,"threshold_uncertainty_score":0.2572499},"labels":[],"label_agreement":null},{"id":"W2144607013","doi":"10.1002/bit.20415","title":"Fractionation of bovine serum albumin and monoclonal antibody alemtuzumab using carrier phase ultrafiltration","year":2005,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Ultrafiltration (renal); Chromatography; Chemistry; Alemtuzumab; Fractionation; Membrane; Ionic strength; Permeation; Bovine serum albumin; Monoclonal antibody; Antibody; Biochemistry; Aqueous solution; Biology; Immunology; Organic chemistry","score_opus":0.009656877803423922,"score_gpt":0.2793067954599338,"score_spread":0.26964991765650986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144607013","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.968978,0.0017114547,0.028424006,0.00065650657,0.000032952106,0.000108718974,0.000051817486,0.000024282417,0.000012267126],"genre_scores_gemma":[0.9955228,0.0003306152,0.0039951834,0.000022736525,0.00004055748,0.000003998722,0.000068010704,0.0000050447175,0.000011046966],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995034,0.000010480615,0.00015148666,0.0001936355,0.000042948686,0.00009808806],"domain_scores_gemma":[0.9997527,0.0000050438807,0.000051951145,0.00012808916,0.000033055778,0.000029173498],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000100273974,0.000086769585,0.00008719425,0.00007065765,0.000050037623,0.00000612094,0.000042519216,0.00024057426,0.00000665407],"category_scores_gemma":[0.000040247658,0.00008848694,0.000018344745,0.00006822749,0.000101188554,0.000010454767,0.00002499608,0.000075774355,2.6686914e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032047283,0.00003398665,0.0009062373,0.000016132093,0.000019754365,2.1353233e-7,0.000012348737,0.00008504149,0.98433256,0.00034091345,0.0000037739774,0.014216987],"study_design_scores_gemma":[0.00048806283,0.00015334033,0.0026202362,0.0000062901618,0.000011971235,0.00003548313,0.0000322371,0.010659398,0.977613,0.000014414583,0.0082591735,0.00010644277],"about_ca_topic_score_codex":0.000005843492,"about_ca_topic_score_gemma":0.0000052712767,"teacher_disagreement_score":0.026544811,"about_ca_system_score_codex":0.000010219375,"about_ca_system_score_gemma":0.000019204901,"threshold_uncertainty_score":0.36083928},"labels":[],"label_agreement":null},{"id":"W2150408402","doi":"10.1042/ba20010019","title":"Process characterization for metal‐affinity chromatography of an Fc fusion protein: a design‐of‐experiments approach","year":2001,"lang":"en","type":"article","venue":"Biotechnology and Applied Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research & Development Corporation","funders":"","keywords":"Robustness (evolution); Fractional factorial design; Fusion; Computer science; Design of experiments; Process design; Factorial experiment; Process (computing); Biological system; Elution; Biochemical engineering; Process engineering; Chromatography; Chemistry; Mathematics; Process integration; Machine learning; Engineering; Biology; Statistics; Biochemistry","score_opus":0.014716020669242677,"score_gpt":0.2506513851326128,"score_spread":0.23593536446337013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2150408402","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9652722,0.00028431104,0.03331659,0.00004846904,0.000009111154,0.00087817205,0.00005588881,0.00003267641,0.000102563965],"genre_scores_gemma":[0.98897344,0.00008233676,0.0099941185,0.000015706997,0.00002507125,0.00036021986,0.0005187286,0.000012592671,0.000017760323],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990337,0.00001924128,0.0002706322,0.00044047515,0.00007871214,0.00015727317],"domain_scores_gemma":[0.999251,0.0000039261945,0.00022045236,0.00040173373,0.00007582701,0.000047032783],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020118435,0.00015935372,0.00020758988,0.000049546386,0.00007438473,0.000005264766,0.00020825966,0.0005675554,0.000004229234],"category_scores_gemma":[0.00004023027,0.00015229278,0.000048178124,0.00017296137,0.000320589,0.0000047434055,0.000056823756,0.00007529133,1.8638598e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004940671,0.0003891812,0.00009050482,0.00019014423,0.00003426365,8.387252e-8,0.000021311083,0.0000017317451,0.9950572,0.00028198375,0.0000012428129,0.0034382434],"study_design_scores_gemma":[0.0005804416,0.00024699257,0.00026238928,0.0000094016,0.000015448319,0.000007530625,0.00012805618,0.00010335721,0.9979846,0.00022433844,0.0002822848,0.00015518996],"about_ca_topic_score_codex":8.6310314e-7,"about_ca_topic_score_gemma":1.3295798e-7,"teacher_disagreement_score":0.023701247,"about_ca_system_score_codex":0.000004478154,"about_ca_system_score_gemma":0.00004784256,"threshold_uncertainty_score":0.62103194},"labels":[],"label_agreement":null},{"id":"W2150596866","doi":"10.1016/j.chroma.2015.11.003","title":"Absence of experimental evidence of a delta-shock in the system phenetole and 4-tert-butylphenol on Zorbax 300SB-C18","year":2015,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Shock (circulatory); Thermodynamics; Chromatography; Binary number; Langmuir; Work (physics); Adsorption; Binary system; Delta; Physical chemistry; Physics","score_opus":0.030220724043599146,"score_gpt":0.2894260971847987,"score_spread":0.25920537314119957,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2150596866","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9875252,0.0117979655,0.00020462905,0.00006433556,0.000043685377,0.00014635232,0.000004845407,0.0000015201541,0.00021145339],"genre_scores_gemma":[0.9993599,0.000114186965,0.000439998,0.000039922128,0.000031613134,0.0000074567465,7.780183e-7,0.0000044202175,0.0000016987395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989658,0.00014964257,0.0004251177,0.00011423593,0.00025437083,0.00009085676],"domain_scores_gemma":[0.9991647,0.00003103233,0.00036530962,0.00024238833,0.00013709856,0.000059465256],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00066957896,0.00008645712,0.00019144079,0.0000766203,0.000018599536,0.000009715225,0.00023966686,0.00006035501,0.0000018173671],"category_scores_gemma":[0.000079875506,0.000058780064,0.00010701942,0.00014379549,0.00012884615,0.000010256753,0.00002830929,0.00007411818,2.1508902e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00068955176,0.0004060249,0.03289753,0.00018176669,0.00006513099,0.000008917107,0.0015084484,0.000026257412,0.9628236,0.00056610233,0.00023675567,0.0005898933],"study_design_scores_gemma":[0.0016771266,0.0028061643,0.047798477,0.00078409346,0.000026156975,0.00025067647,0.005672239,0.00012090557,0.93976,0.00014426635,0.0007833773,0.0001765102],"about_ca_topic_score_codex":0.000018782612,"about_ca_topic_score_gemma":0.0000049877212,"teacher_disagreement_score":0.023063617,"about_ca_system_score_codex":0.000011912199,"about_ca_system_score_gemma":0.000069344904,"threshold_uncertainty_score":0.23969814},"labels":[],"label_agreement":null},{"id":"W2153728088","doi":"10.1139/o05-148","title":"Role of osmolytes as chemical chaperones during the refolding of aminoacylase","year":2006,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Tsinghua University","keywords":"Osmolyte; Chemistry; Glycerol; Biochemistry; Sucrose; Betaine; Enzyme; Proline; Biophysics; Amino acid; Biology","score_opus":0.003276874432199528,"score_gpt":0.20189607841371984,"score_spread":0.1986192039815203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2153728088","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900889,0.006404375,0.000007636258,0.00004496798,0.000014467598,0.00007760464,0.000027737713,0.0000051911684,0.0033291455],"genre_scores_gemma":[0.99921846,0.00016067324,0.000094790674,0.000013631643,0.000079381905,0.000013035415,0.00007129861,0.0000055156424,0.000343229],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99931586,0.000030727246,0.0002256705,0.0002505862,0.00004222344,0.00013491818],"domain_scores_gemma":[0.9994873,0.000017112534,0.0001241254,0.00029183165,0.000049057064,0.000030595274],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010902405,0.000103980994,0.00012717633,0.0000101324285,0.00004521934,0.000003278307,0.00015453366,0.00017621352,0.000021071777],"category_scores_gemma":[0.000048885104,0.00007830975,0.00005803726,0.00004301185,0.00034299667,0.0000014275097,0.000095513715,0.0000558911,7.4413964e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007061233,0.00006745524,0.0041684518,0.00006527934,0.000008752651,1.3181169e-7,0.000012372569,6.3620786e-7,0.99468154,0.00023250702,0.000006782342,0.0006854708],"study_design_scores_gemma":[0.00023925719,0.000048339833,0.0021555054,0.000004622769,0.0000075859793,0.0000076189062,0.00010425408,0.0000048892493,0.99458593,0.0003293481,0.0024267938,0.00008588186],"about_ca_topic_score_codex":0.00004470944,"about_ca_topic_score_gemma":0.0000012209097,"teacher_disagreement_score":0.00912957,"about_ca_system_score_codex":0.000004740129,"about_ca_system_score_gemma":0.000027907594,"threshold_uncertainty_score":0.31933787},"labels":[],"label_agreement":null},{"id":"W2157852264","doi":"10.1021/bp020002i","title":"pH Transitions in Ion‐Exchange Systems: Role in the Development of a Cation‐Exchange Process for a Recombinant Protein","year":2002,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research & Development Corporation","funders":"","keywords":"Chemistry; Salt (chemistry); Ion exchange; Ion-exchange resin; Ion; Ion chromatography; Recombinant DNA; Salt solution; Chromatography; Inorganic chemistry; Organic chemistry; Biochemistry","score_opus":0.02725598172265561,"score_gpt":0.27173268687571184,"score_spread":0.24447670515305622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157852264","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9813111,0.009158394,0.0011208034,0.004607536,0.00005373754,0.0035895638,0.000030702788,0.000031417192,0.00009679089],"genre_scores_gemma":[0.9929842,0.000052290376,0.0010562157,0.000021482887,0.000017010967,0.0057368525,0.00005574694,0.0000107434225,0.00006549282],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885297,0.000091773705,0.0003857744,0.00032809706,0.00009904515,0.00024236886],"domain_scores_gemma":[0.9993812,0.000006447338,0.00012944434,0.00037848298,0.00008431902,0.000020144687],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054704945,0.00012933029,0.00017020291,0.00014760604,0.00007481466,0.0000094524485,0.00034518525,0.00036831797,0.000006367993],"category_scores_gemma":[0.00006836462,0.00010199377,0.00003897369,0.0003296337,0.00016532291,0.000005605322,0.000029843677,0.00011848696,0.00000207479],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007366112,0.009854578,0.010126289,0.0053481157,0.00020326006,0.000011706465,0.038388297,0.000029712666,0.58520335,0.012954392,0.00037649996,0.33676723],"study_design_scores_gemma":[0.0039675026,0.0009965823,0.005648465,0.00038333988,0.00002416626,0.000032746637,0.0075785667,0.0019852188,0.8621649,0.0010431266,0.11543921,0.0007361661],"about_ca_topic_score_codex":0.000007754434,"about_ca_topic_score_gemma":0.00026884166,"teacher_disagreement_score":0.33603105,"about_ca_system_score_codex":0.000031218296,"about_ca_system_score_gemma":0.000055319346,"threshold_uncertainty_score":0.4159185},"labels":[],"label_agreement":null},{"id":"W2168693435","doi":"10.1021/bp0343716","title":"","year":2004,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Ultrafiltration (renal); Fractionation; Chromatography; Human serum albumin; Membrane; Ionic strength; Chemistry; Salt (chemistry); Serum albumin; Phase (matter); Selectivity; Albumin; Analytical Chemistry (journal); Biochemistry; Aqueous solution","score_opus":0.007989208247269416,"score_gpt":0.2516344772105639,"score_spread":0.2436452689632945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168693435","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96453995,0.004729864,0.010427889,0.019177346,0.00010985838,0.0006839299,0.000012185904,0.00028566856,0.000033285432],"genre_scores_gemma":[0.9866149,0.00021584163,0.012233437,0.00040927288,0.00007991032,0.0003354026,0.00006574175,0.000024496283,0.000021011892],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99802506,0.000056779074,0.00034321987,0.00086762663,0.00016025678,0.00054703455],"domain_scores_gemma":[0.99833006,0.000003223386,0.00013688325,0.001289567,0.00011678885,0.0001234848],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003334911,0.00026030603,0.00020424627,0.00010860963,0.00023399484,0.00003008789,0.0007229051,0.000909301,0.000002571705],"category_scores_gemma":[0.00021548344,0.00025032478,0.000116547,0.000306655,0.0012290449,0.0000053194376,0.0003219939,0.00022284452,0.000009662363],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026442268,0.00057526806,0.02107137,0.000022546436,0.00007126176,0.000014836346,0.000050487775,0.000034754637,0.9124625,0.026354084,0.000014072067,0.039064426],"study_design_scores_gemma":[0.0017434577,0.000693131,0.017098235,0.0000087667595,0.000008579714,0.00008883989,0.00010337456,0.0000024855988,0.95317066,0.0033585106,0.023405904,0.00031808834],"about_ca_topic_score_codex":0.000014676322,"about_ca_topic_score_gemma":0.00005627309,"teacher_disagreement_score":0.04070816,"about_ca_system_score_codex":0.00004176232,"about_ca_system_score_gemma":0.0001351256,"threshold_uncertainty_score":0.9999949},"labels":[],"label_agreement":null},{"id":"W2170977092","doi":"10.1016/j.jconrel.2014.10.032","title":"Mathematical model accurately predicts protein release from an affinity-based delivery system","year":2014,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Kinetics; Dissociation (chemistry); Dissociation rate; Biophysics; Chemistry; Receptor–ligand kinetics; Controlled release; Biological system; Nanotechnology; Materials science; Receptor; Biochemistry; Physical chemistry; Biology; Physics","score_opus":0.016084577401739065,"score_gpt":0.2575725468506742,"score_spread":0.24148796944893514,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2170977092","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86837447,0.0005781486,0.12915424,0.00046162977,0.000066874054,0.00064931053,0.000039260354,0.000022965663,0.00065311516],"genre_scores_gemma":[0.99410313,0.000014348721,0.0050227907,0.00030524735,0.00033803348,0.000051722105,0.000029395273,0.00002498909,0.00011035265],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99766093,0.0005888874,0.00086528633,0.00027445654,0.00038313065,0.00022731202],"domain_scores_gemma":[0.9977044,0.00008771955,0.0006712782,0.00057678943,0.0005494758,0.00041035155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010169485,0.00021626423,0.00055689755,0.000073836985,0.00010035769,0.000060808452,0.0003658856,0.00023494447,0.000027351398],"category_scores_gemma":[0.0014398597,0.0001638018,0.00032633037,0.00005931014,0.00007525367,0.000020217985,0.000030434638,0.00027092057,0.000014613956],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.04110245,0.002589786,0.0002274885,0.00036039558,0.00067327986,0.00007912835,0.0001416043,0.028192574,0.91094923,0.0043566762,0.00090936443,0.01041805],"study_design_scores_gemma":[0.029617568,0.0016542058,0.00024425687,0.00025730868,0.0003485146,0.000036004996,0.00014747045,0.86656964,0.09622461,0.0024676153,0.0019560335,0.00047675357],"about_ca_topic_score_codex":0.0000052594332,"about_ca_topic_score_gemma":0.0000034774423,"teacher_disagreement_score":0.83837706,"about_ca_system_score_codex":0.000041732517,"about_ca_system_score_gemma":0.00045819572,"threshold_uncertainty_score":0.66796434},"labels":[],"label_agreement":null},{"id":"W2198956635","doi":"10.1016/j.memsci.2015.04.067","title":"A technique for drying and storing a protein as a soluble composite thin film on the surface of an ultrafiltration membrane","year":2015,"lang":"en","type":"article","venue":"Journal of Membrane Science","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Ultrafiltration (renal); Membrane; Chromatography; Biopharmaceutical; Monoclonal antibody; Chemistry; Composite number; Capillary action; Thin-film composite membrane; Chemical engineering; Materials science; Composite material; Antibody; Engineering; Biotechnology","score_opus":0.028445303993407143,"score_gpt":0.2929232029273372,"score_spread":0.26447789893393003,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2198956635","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950228,0.00012222966,0.0033708094,0.00063728757,0.000057238864,0.00052100787,0.0000030261995,0.000002851154,0.00026277767],"genre_scores_gemma":[0.9920001,0.000012310483,0.00781913,0.000056408437,0.00003565578,0.0000137840925,0.0000010846846,0.0000044277026,0.000057082718],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990903,0.0000862626,0.0002441687,0.00015750172,0.0003032217,0.00011851245],"domain_scores_gemma":[0.99900466,0.000030200596,0.0002552493,0.00021348253,0.00039060038,0.00010580633],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0035553353,0.00007017536,0.0001120061,0.00003980917,0.00012722601,0.000041575706,0.00029765887,0.000046159785,0.0000019297424],"category_scores_gemma":[0.00072295417,0.000047583155,0.00003751905,0.00013598817,0.00021569055,0.00003348864,0.000025516321,0.00009743374,1.8520858e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021229035,0.000053326352,0.000028272658,0.000020807172,0.0000042855913,3.6260616e-7,0.00024022342,0.0008217242,0.9980821,0.00036768132,0.0000053980143,0.00016350592],"study_design_scores_gemma":[0.00034893397,0.0007390816,0.00009027394,0.000040302228,0.0000048016745,0.000041543626,0.00023476277,0.001079188,0.99668366,0.00030111478,0.0003788207,0.000057542882],"about_ca_topic_score_codex":0.000012564362,"about_ca_topic_score_gemma":0.000004067228,"teacher_disagreement_score":0.0044483207,"about_ca_system_score_codex":0.000020299114,"about_ca_system_score_gemma":0.000326931,"threshold_uncertainty_score":0.19403848},"labels":[],"label_agreement":null},{"id":"W2203056953","doi":"10.1016/j.ejpb.2015.06.008","title":"Novel biodegradable polymers for local growth factor delivery","year":2015,"lang":"en","type":"review","venue":"European Journal of Pharmaceutics and Biopharmaceutics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Drug delivery; Polymer; Biodegradable polymer; Nanotechnology; Dosage form; Controlled release; Materials science; Chemistry; Chromatography; Organic chemistry","score_opus":0.12524700701114247,"score_gpt":0.37274615322925253,"score_spread":0.24749914621811006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2203056953","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009509383,0.9856171,0.011886074,0.00007662406,0.0007460685,0.0006102535,0.00075292506,0.000011168135,0.000204701],"genre_scores_gemma":[0.0017590064,0.9943437,0.0023657668,0.00027217806,0.0007858082,0.0000067768938,0.00011780511,0.00011193787,0.00023704274],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.997222,0.00043370196,0.0011638475,0.00043973804,0.00031824663,0.00042245508],"domain_scores_gemma":[0.9972894,0.000057872767,0.0010442035,0.00029350896,0.0007134014,0.00060157006],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0017192815,0.00054790115,0.00096551474,0.00019288716,0.00012795682,0.000089552865,0.00062547915,0.00019556229,0.00001811458],"category_scores_gemma":[0.0001168185,0.00043504033,0.00059217506,0.00018658966,0.0002903211,0.00001390712,0.00022354872,0.0005558966,0.0000074127634],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001790638,0.00018621299,0.0000044399526,0.0028984502,0.00050113775,0.00001949946,0.000030231407,0.0000021035223,0.004044372,0.000022932583,0.0007776529,0.9913339],"study_design_scores_gemma":[0.0017452734,0.00037053062,0.0000016480539,0.00039894864,0.0009547013,0.00033671528,0.00003721256,0.00009440811,0.0035209104,0.000004843256,0.9920517,0.00048307303],"about_ca_topic_score_codex":0.0000010307929,"about_ca_topic_score_gemma":3.1193656e-7,"teacher_disagreement_score":0.99127406,"about_ca_system_score_codex":0.00007252221,"about_ca_system_score_gemma":0.0005730701,"threshold_uncertainty_score":0.99981016},"labels":[],"label_agreement":null},{"id":"W2205723948","doi":"10.1016/j.chroma.2015.12.066","title":"A mixed-mode resin with tryptamine ligand for human serum albumin separation","year":2015,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"International Science and Technology Cooperation Programme; Provincial Health Services Authority; National Natural Science Foundation of China","keywords":"Human serum albumin; Adsorption; Tryptamine; Chemistry; Chromatography; Pichia pastoris; Elution; Ligand (biochemistry); Monomer; Tryptophan; Salt (chemistry); Serum albumin; Nuclear chemistry; Recombinant DNA; Organic chemistry; Biochemistry; Polymer; Amino acid; Receptor","score_opus":0.025590199866680815,"score_gpt":0.31032704325093485,"score_spread":0.28473684338425403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2205723948","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987794,0.00086734083,0.010458382,0.00031141777,0.00006301621,0.00020814338,0.00001699578,0.0000052811265,0.00027546764],"genre_scores_gemma":[0.99601185,0.00001991843,0.003602406,0.000064922155,0.00017193622,0.00001449288,0.00002320997,0.000011386909,0.00007986876],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992324,0.000049915514,0.000296623,0.00013226374,0.00016585454,0.00012293365],"domain_scores_gemma":[0.9990269,0.0000072923144,0.00027689,0.0001971062,0.00036503674,0.00012675421],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038186146,0.0001001189,0.00015837353,0.00008398827,0.000056934663,0.000027883689,0.00012834975,0.00008715573,0.0000018605093],"category_scores_gemma":[0.000055871715,0.00007678395,0.00013218055,0.00011746282,0.000067630834,0.000010506693,0.000011523737,0.00006311722,4.544726e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011411613,0.0003734939,0.011803182,0.00006924756,0.00022395283,0.0000058791466,0.00026743044,0.000055540535,0.9742138,0.0006860286,0.009630351,0.0015299303],"study_design_scores_gemma":[0.004093876,0.0031630748,0.016948184,0.000052256222,0.00006776584,0.00016671821,0.0002778456,0.00006135849,0.89478093,0.0017895858,0.07835227,0.00024613825],"about_ca_topic_score_codex":0.000003835848,"about_ca_topic_score_gemma":0.000052565585,"teacher_disagreement_score":0.079432875,"about_ca_system_score_codex":0.000010102826,"about_ca_system_score_gemma":0.00012404591,"threshold_uncertainty_score":0.31311586},"labels":[],"label_agreement":null},{"id":"W2227822952","doi":"10.1021/acschembio.5b00806","title":"Stable Colloidal Drug Aggregates Catch and Release Active Enzymes","year":2016,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Cancer Society Research Institute; University of Toronto; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Colloid; Chemistry; Ionic strength; Trypsin; Enzyme; Particle (ecology); Adsorption; Chemical engineering; Particle size; Chromatography; Biophysics; Biochemistry; Organic chemistry; Biology","score_opus":0.006683834659460061,"score_gpt":0.2362943540696446,"score_spread":0.22961051941018454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2227822952","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99466753,0.00234078,0.000119458404,0.002052662,0.000044266908,0.00015547503,0.000095395364,0.000019834471,0.0005046193],"genre_scores_gemma":[0.99785596,0.00055656204,0.0002374546,0.00027252798,0.00008915423,0.0000484532,0.000082575556,0.000009441104,0.0008478524],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990673,0.00007263624,0.00015516758,0.00042473592,0.000040211064,0.00023996674],"domain_scores_gemma":[0.9993922,0.000068538124,0.00006203008,0.00029136913,0.000073013056,0.00011285773],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117401054,0.00012809657,0.0001447777,0.00001516799,0.000045878453,0.0000069894722,0.00014933672,0.00019579598,0.000047624268],"category_scores_gemma":[0.0004631399,0.0000868351,0.000038037073,0.000044466276,0.00033631016,0.0000042771967,0.00013630072,0.000064342006,0.000014386146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015157972,0.000040753104,0.002841771,0.0000053407343,0.000021737873,4.011354e-7,0.000019331112,1.5361897e-8,0.9750407,0.0006554475,0.0006832511,0.020539708],"study_design_scores_gemma":[0.00048663607,0.000052586434,0.00043605838,0.000004383101,0.000005602117,0.0000057641564,0.00001954575,5.243823e-7,0.91896766,0.0014199053,0.078469954,0.0001313819],"about_ca_topic_score_codex":0.000027249336,"about_ca_topic_score_gemma":0.000009006213,"teacher_disagreement_score":0.07778671,"about_ca_system_score_codex":0.00001813738,"about_ca_system_score_gemma":0.000053139196,"threshold_uncertainty_score":0.35410327},"labels":[],"label_agreement":null},{"id":"W2230072570","doi":"10.1385/1-59259-922-2:145","title":"Fusion to Albumin as a Means to Slow the Clearance of Small Therapeutic Proteins Using the &lt;I&gt;Pichia pastoris&lt;/I&gt; Expression System: A Case Study","year":2005,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Blood Services; McMaster University","funders":"Canadian Blood Services; Heart and Stroke Foundation of Canada","keywords":"Pichia pastoris; Fusion protein; Albumin; Yeast; Biochemistry; Human serum albumin; Pichia; Saccharomyces cerevisiae; Chemistry; Serum albumin; Biology; Recombinant DNA; Gene","score_opus":0.04574566084589676,"score_gpt":0.2868370717761568,"score_spread":0.24109141093026004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2230072570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9821971,0.0031879025,0.0073426687,0.0001607277,0.000100784586,0.0045704287,0.0000139155745,0.000035465182,0.0023910196],"genre_scores_gemma":[0.9965781,0.000011741669,0.00079544086,0.0002330783,0.00023574624,0.00059547037,0.000002239834,0.000031489184,0.0015166837],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979021,0.0006051902,0.0003990899,0.00049604755,0.0002987071,0.0002988982],"domain_scores_gemma":[0.9981952,0.0000269949,0.00016790708,0.001295863,0.00018861811,0.00012543339],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008042479,0.00022328076,0.00021001327,0.00004217817,0.00053353386,0.000060624207,0.00054966565,0.000115720766,0.0000061477112],"category_scores_gemma":[0.00006977504,0.00014684616,0.000103061226,0.00004467906,0.00010540032,0.000005043119,0.00026619862,0.00013346487,0.000003704891],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041464236,0.0003056965,0.0000241959,0.000085664964,0.00007319754,0.000019549028,0.010305347,0.0004468119,0.95947057,0.0011264848,0.0001402792,0.02758759],"study_design_scores_gemma":[0.0012988925,0.000992827,0.0007063044,0.0002127691,0.0001534426,0.00012659148,0.003026301,0.0009416641,0.47912183,0.000024232018,0.5128333,0.00056184764],"about_ca_topic_score_codex":0.00035355796,"about_ca_topic_score_gemma":0.0019487493,"teacher_disagreement_score":0.512693,"about_ca_system_score_codex":0.000055944565,"about_ca_system_score_gemma":0.0000866113,"threshold_uncertainty_score":0.5988212},"labels":[],"label_agreement":null},{"id":"W2280108561","doi":"10.1016/j.jmb.2016.02.016","title":"Ensemble Modeling and Intracellular Aggregation of an Engineered Immunoglobulin-Like Domain","year":2016,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Protein aggregation; Biophysics; Protein folding; Protein structure; Immunoglobulin domain; Biology; Biochemistry","score_opus":0.007213286218066662,"score_gpt":0.24333876657987003,"score_spread":0.23612548036180336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2280108561","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6824106,0.0030106686,0.31424254,0.00018070074,0.00006562955,0.000064237305,0.0000049603204,0.0000019620077,0.000018714089],"genre_scores_gemma":[0.9874454,0.00035661165,0.012058358,0.00004987654,0.000056117293,0.000002450375,0.000010541071,0.000009639492,0.000010989251],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990561,0.0001723698,0.00040270374,0.00016396045,0.00007630375,0.00012853941],"domain_scores_gemma":[0.9991952,0.000011521185,0.00023699887,0.00025113957,0.00022881941,0.00007629617],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005393745,0.00010012909,0.00018439388,0.000062088366,0.000022549399,0.0000052935147,0.00015339475,0.00016920026,0.0000068785157],"category_scores_gemma":[0.00016309314,0.000071168964,0.00008030586,0.00004354201,0.00008923949,0.000007446733,0.000039214945,0.0000680092,6.130513e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001591244,0.0000490246,0.0001687097,0.000007851613,0.00004734184,0.000004766,0.0000243866,0.000091356895,0.98081005,0.0005636616,0.0000031007628,0.018070621],"study_design_scores_gemma":[0.0010167967,0.0007722981,0.00014485387,0.000021456248,0.000017525515,0.0001394921,0.000037558922,0.00029269676,0.9903422,0.005174687,0.0019229006,0.00011755686],"about_ca_topic_score_codex":0.0000033250674,"about_ca_topic_score_gemma":0.0000016455999,"teacher_disagreement_score":0.30503482,"about_ca_system_score_codex":0.000011807027,"about_ca_system_score_gemma":0.0000644846,"threshold_uncertainty_score":0.29021862},"labels":[],"label_agreement":null},{"id":"W2284494162","doi":"10.1111/hae.12890","title":"Reduced immunogenic response to residual <scp>CHO</scp> cell protein in recombinant factor <scp>IX</scp> (<scp>IB</scp>1001) drug product in normal healthy rabbits","year":2016,"lang":"en","type":"letter","venue":"Haemophilia","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Emergent BioSolutions (Canada)","funders":"","keywords":"Chinese hamster ovary cell; Recombinant DNA; Immunogenicity; Factor IX; CHOP; Medicine; Antibody; Haemophilia; Adjuvant; Haemophilia B; Polyclonal antibodies; Immunology; Haemophilia A; Pharmacology; Virology; Molecular biology; Chemistry; Biology; Internal medicine; Biochemistry; Receptor; Surgery","score_opus":0.014287841318680477,"score_gpt":0.24920273321256395,"score_spread":0.23491489189388348,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2284494162","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92098254,0.0045201317,0.000023375727,0.06376993,0.0012750907,0.0075908857,0.0007823314,0.0001218894,0.00093384425],"genre_scores_gemma":[0.73164564,0.0012598515,0.0013943973,0.06316528,0.0061237663,0.0067764325,0.0033006205,0.0008535529,0.18548046],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.98747176,0.0030539597,0.0022465165,0.0034577546,0.0010739363,0.0026960878],"domain_scores_gemma":[0.99343944,0.00075260736,0.0009959711,0.0037144537,0.00052683434,0.00057068915],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.00370094,0.0015008925,0.0014971545,0.0009110323,0.00029788306,0.0001771778,0.0020818787,0.0021440634,0.00002645914],"category_scores_gemma":[0.008599432,0.0014239807,0.00050756417,0.0009685352,0.0003547413,0.00005433854,0.00080587313,0.002857966,0.00044609373],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038517074,0.00043793465,0.0006021583,0.0005589321,0.000075466625,0.00021843058,0.0013116687,0.000005061098,0.59540635,0.0000054567477,0.39912492,0.0018684616],"study_design_scores_gemma":[0.0018517759,0.0005364201,0.006712748,0.00023728902,0.000019341842,0.00003431315,0.0001460097,0.0000018129828,0.39543474,0.00013841617,0.59467185,0.00021526577],"about_ca_topic_score_codex":0.00024282458,"about_ca_topic_score_gemma":0.00022311305,"teacher_disagreement_score":0.1999716,"about_ca_system_score_codex":0.00066961953,"about_ca_system_score_gemma":0.002094055,"threshold_uncertainty_score":0.99977404},"labels":[],"label_agreement":null},{"id":"W2285092458","doi":"10.1080/19420862.2015.1122150","title":"Rapid characterization of biotherapeutic proteins by size-exclusion chromatography coupled to native mass spectrometry","year":2015,"lang":"en","type":"article","venue":"mAbs","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":139,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Lethbridge","keywords":"Chemistry; Chromatography; Mass spectrometry; Electrospray ionization; Size-exclusion chromatography; Critical quality attributes; Tandem mass spectrometry; Characterization (materials science); Electrospray; Liquid chromatography–mass spectrometry; Nanotechnology; Particle size; Biochemistry; Enzyme; Materials science","score_opus":0.011772013105947972,"score_gpt":0.24631361338885618,"score_spread":0.2345416002829082,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2285092458","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9703949,0.0005006933,0.027211314,0.0006969594,0.00006953553,0.00069219194,0.00007490011,0.000020208134,0.0003392903],"genre_scores_gemma":[0.99749005,0.0000695784,0.0016621788,0.00026503947,0.00004382966,0.00006150798,0.00018120975,0.000013976395,0.0002126336],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917555,0.000073300005,0.00019515713,0.00025431308,0.00016813427,0.00013353076],"domain_scores_gemma":[0.999324,0.0000062685185,0.00010362431,0.00029695852,0.000168332,0.00010081316],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025267288,0.00010811945,0.0001297024,0.00005816475,0.000036208166,0.000012206868,0.0001418939,0.000098734876,0.00007391068],"category_scores_gemma":[0.00011697046,0.00010134836,0.000053830994,0.0002788341,0.000054265736,0.000004523722,0.000042209977,0.00004357395,0.000011259488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001215617,0.00009636808,0.0007971879,0.000016737298,0.00002246019,1.4503084e-7,0.00007954492,3.6383986e-7,0.9978552,0.000044344637,0.000118466276,0.0008476344],"study_design_scores_gemma":[0.00051513844,0.00036560558,0.008447563,0.000008062267,0.0000057319107,9.3998324e-7,0.000040574367,0.00005511842,0.9665589,0.00010495508,0.023764275,0.000133161],"about_ca_topic_score_codex":0.000009978886,"about_ca_topic_score_gemma":0.0000019004316,"teacher_disagreement_score":0.03129631,"about_ca_system_score_codex":0.000021970056,"about_ca_system_score_gemma":0.000055044027,"threshold_uncertainty_score":0.41328663},"labels":[],"label_agreement":null},{"id":"W2287819496","doi":"","title":"Measurement of D-dimer concentrations in citrated whole blood samples following storage at room temperature.","year":2012,"lang":"en","type":"article","venue":"Bristol Research (University of Bristol)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Blood preservation; Chemistry; Whole blood; Chromatography; Environmental science; Medicine; Internal medicine; Physiology","score_opus":0.05434171263723594,"score_gpt":0.28744035242433846,"score_spread":0.23309863978710252,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2287819496","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935585,0.004660547,0.00038445258,0.0002295329,0.000042805954,0.0003741159,0.00006879451,0.000007575206,0.0006736347],"genre_scores_gemma":[0.99889684,0.00008354718,0.00039222676,0.000008322889,0.00002006895,0.0000021598423,0.00009332213,0.000008904001,0.00049461506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982419,0.00035750665,0.00019131969,0.00028210785,0.0005738872,0.00035326264],"domain_scores_gemma":[0.9988457,0.000023407702,0.00009998067,0.0004255433,0.00044811773,0.0001572325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015990181,0.000100661855,0.00020537597,0.00012463373,0.00021295215,0.000008666663,0.000313842,0.0001530196,0.000048841892],"category_scores_gemma":[0.00033104335,0.00012679421,0.00012478445,0.00034960744,0.0002104048,0.00002334408,0.00016063948,0.00018757835,0.000008547216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014295,0.00042679164,0.0591059,0.000046200854,0.0000690052,0.0000043502337,0.00035976584,0.000012085239,0.93821305,0.00011134994,0.0012954278,0.00021312141],"study_design_scores_gemma":[0.003385731,0.0004263141,0.39437854,0.00013230051,0.000080807076,0.0000090191015,0.004555518,0.000082494014,0.50350153,0.000060973427,0.09290393,0.00048281334],"about_ca_topic_score_codex":0.0006965636,"about_ca_topic_score_gemma":0.0012646576,"teacher_disagreement_score":0.43471152,"about_ca_system_score_codex":0.00015458278,"about_ca_system_score_gemma":0.0002761793,"threshold_uncertainty_score":0.51705176},"labels":[],"label_agreement":null},{"id":"W2302538535","doi":"10.1002/prca.201500057","title":"Development of an SRM method for absolute quantitation of MYDGF/C19orf10 protein","year":2015,"lang":"en","type":"article","venue":"PROTEOMICS - CLINICAL APPLICATIONS","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Health Sciences Centre; Manitoba Health","funders":"","keywords":"Absolute (philosophy); Chromatography; Chemistry; Computer science","score_opus":0.1314732274167921,"score_gpt":0.45327166090152654,"score_spread":0.32179843348473447,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2302538535","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.21204118,0.000081899256,0.7845965,0.00022349307,0.000021891121,0.0027919342,0.00006492629,0.0000122974825,0.00016588943],"genre_scores_gemma":[0.19996785,0.000006459012,0.79687554,0.000036620586,0.00006646183,0.0026964578,0.00025046204,0.000013975718,0.00008615761],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982958,0.000115790295,0.0009386384,0.0003865188,0.00013190426,0.00013136984],"domain_scores_gemma":[0.99821305,0.000047543366,0.00044798144,0.00057743426,0.0005736339,0.0001403549],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021704386,0.00010617844,0.00022684794,0.000032476553,0.0000579204,0.000007631014,0.00029049465,0.00018837958,0.000003172139],"category_scores_gemma":[0.00061383675,0.000105217616,0.00010603171,0.0001122437,0.0001188464,0.0000071967843,0.00006483978,0.00007963567,0.000004791516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004774538,0.0012995595,0.00036236292,0.00015638555,0.00008066617,2.8705603e-8,0.000189166,0.00003931487,0.88480824,0.01967935,0.0000730263,0.09283442],"study_design_scores_gemma":[0.0014579146,0.00054571993,0.0031046355,0.000012760023,0.000031599222,8.285675e-7,0.00014958982,0.002300936,0.8802624,0.016601562,0.09527564,0.0002564429],"about_ca_topic_score_codex":0.0000095659925,"about_ca_topic_score_gemma":0.00003838731,"teacher_disagreement_score":0.09520262,"about_ca_system_score_codex":0.000015141233,"about_ca_system_score_gemma":0.00043300338,"threshold_uncertainty_score":0.429065},"labels":[],"label_agreement":null},{"id":"W2308043675","doi":"10.1016/j.chroma.2016.03.066","title":"Negative chromatography of hepatitis B virus-like particle: Comparative study of different adsorbent designs","year":2016,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Chemistry; Chromatography; Adsorption; Elution; Column chromatography; Packed bed; Organic chemistry","score_opus":0.025975196442083088,"score_gpt":0.28011606742560113,"score_spread":0.25414087098351806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2308043675","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99637157,0.00081988267,0.0021542702,0.00004450424,0.00009402425,0.00040155833,0.000043648764,0.000005221374,0.0000653293],"genre_scores_gemma":[0.99903286,0.00048726128,0.00038782894,0.000016258264,0.00003607084,0.000021080912,0.0000018735361,0.000010925833,0.000005848998],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980189,0.0003396628,0.000881142,0.00020861303,0.0003723757,0.00017926237],"domain_scores_gemma":[0.9979539,0.00007501288,0.00097429217,0.00037960894,0.00048405363,0.00013316132],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031139908,0.00018911413,0.0005057069,0.00016541322,0.000045795525,0.000009150792,0.00028997124,0.00008074925,0.000060768976],"category_scores_gemma":[0.00006056451,0.00012108674,0.0003776053,0.00031137574,0.000291404,0.000016245105,0.0000520371,0.000079563266,6.5555605e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040546453,0.0020860897,0.2804414,0.00003127177,0.00056190917,0.0000026169312,0.0009263443,0.000002601193,0.7144853,0.00011612973,0.00016268274,0.00077819516],"study_design_scores_gemma":[0.001859906,0.003050639,0.34302682,0.00007240663,0.000067982575,0.000011212671,0.00053161243,0.0000045205284,0.6507642,0.00029880911,0.00019099611,0.000120888595],"about_ca_topic_score_codex":0.000042553787,"about_ca_topic_score_gemma":0.00015404265,"teacher_disagreement_score":0.063721076,"about_ca_system_score_codex":0.000011419709,"about_ca_system_score_gemma":0.00006307954,"threshold_uncertainty_score":0.49377742},"labels":[],"label_agreement":null},{"id":"W2314160643","doi":"10.1021/bm200541r","title":"Integrated Solid-Phase Synthesis and Purification of PEGylated Protein","year":2011,"lang":"en","type":"article","venue":"Biomacromolecules","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"PEGylation; Chemistry; Lysozyme; Propionaldehyde; Diafiltration; Chromatography; PEG ratio; Sodium cyanoborohydride; Microporous material; Protein purification; Membrane; Polyethylene glycol; Biochemistry; Organic chemistry","score_opus":0.024819064027638473,"score_gpt":0.2849994930307416,"score_spread":0.2601804290031032,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2314160643","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939573,0.00072089984,0.003912121,0.000049188147,0.00001804077,0.0003570685,0.000064761705,0.000022288967,0.00089833216],"genre_scores_gemma":[0.9957609,0.000045196117,0.0039272155,0.00001462748,0.000010735519,0.00009205653,0.000064789325,0.000013408103,0.00007106218],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991434,0.0000986581,0.000252853,0.0002959765,0.00007706561,0.0001320003],"domain_scores_gemma":[0.9993117,0.000005315915,0.00012308087,0.0003553289,0.00013522267,0.00006934803],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018505522,0.0001233649,0.00012944962,0.00005094477,0.000045786957,0.000009775306,0.00014151327,0.00012855062,0.000053300213],"category_scores_gemma":[0.00022370224,0.00011122212,0.000048722704,0.000112741014,0.00019842667,0.0000040089667,0.000043119715,0.000036081525,0.00000498089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015881966,0.00023430979,0.00019062693,0.00002786172,0.000033196775,0.0000014624725,0.000080393846,2.4015561e-8,0.9827523,0.00050511706,0.00001985216,0.01599599],"study_design_scores_gemma":[0.00031503604,0.00019399518,0.0034737138,0.00001576737,0.000013947305,0.0000069623356,0.000067600464,0.000036097925,0.99408424,0.00020695041,0.0014587865,0.00012688796],"about_ca_topic_score_codex":0.000051884726,"about_ca_topic_score_gemma":0.000010809591,"teacher_disagreement_score":0.015869102,"about_ca_system_score_codex":0.0000059534195,"about_ca_system_score_gemma":0.000050071107,"threshold_uncertainty_score":0.45355064},"labels":[],"label_agreement":null},{"id":"W2321081577","doi":"10.1021/bm5005756","title":"Prevention of Thermally Induced Aggregation of IgG Antibodies by Noncovalent Interaction with Poly(acrylate) Derivatives","year":2014,"lang":"en","type":"article","venue":"Biomacromolecules","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Agence Nationale de la Recherche","keywords":"Chemistry; Dynamic light scattering; Acrylic acid; Polymer chemistry; Copolymer; Acrylate; Aqueous solution; Monomer; Hydrophobic effect; Protein aggregation; Differential scanning calorimetry; Polymer; Chemical engineering; Organic chemistry; Biochemistry","score_opus":0.011934884675730869,"score_gpt":0.2676088846586511,"score_spread":0.25567399998292023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2321081577","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97628474,0.00056988845,0.022315096,0.000069645444,0.000031234886,0.00019999803,0.000018950095,0.000009055616,0.0005013741],"genre_scores_gemma":[0.9981641,0.00005644667,0.0015419243,0.000016249902,0.000017680473,0.000014846123,0.00012867486,0.00001074504,0.000049290822],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999184,0.00013160218,0.0002510483,0.00021651947,0.00012135556,0.00009546744],"domain_scores_gemma":[0.99926615,0.000010657084,0.00028957013,0.0002536305,0.00015196502,0.000028049542],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016572344,0.00011014602,0.00013526715,0.000039265782,0.00003357947,0.000008127732,0.000106527026,0.000083287174,0.000009927325],"category_scores_gemma":[0.00007049192,0.00009193484,0.000058734353,0.00008071178,0.00011014596,0.000009003746,0.00003254743,0.000032168726,0.0000010191412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016669296,0.00014418013,0.002227491,0.000049333838,0.000050176084,9.495958e-8,0.00009320241,0.0000012693366,0.97074616,0.00015640722,0.000016878126,0.026348114],"study_design_scores_gemma":[0.00037971375,0.00058030046,0.018422527,0.00004804339,0.000012907127,0.000002966369,0.00008520152,0.00003571245,0.9795395,0.000091822076,0.00069996633,0.00010130336],"about_ca_topic_score_codex":0.00003657079,"about_ca_topic_score_gemma":0.00002237959,"teacher_disagreement_score":0.02624681,"about_ca_system_score_codex":0.000008098252,"about_ca_system_score_gemma":0.00003401361,"threshold_uncertainty_score":0.3748994},"labels":[],"label_agreement":null},{"id":"W2327951769","doi":"10.1021/mp300099f","title":"Phase Separation Behavior of Fusidic Acid and Rifampicin in PLGA Microspheres","year":2012,"lang":"en","type":"article","venue":"Molecular Pharmaceutics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Renishaw","keywords":"Fusidic acid; Rifampicin; PLGA; Microsphere; Chemistry; Chromatography; Antibiotics; Pharmacology; Microbiology; Medicine; Chemical engineering; Bacteria; Biochemistry; Biology; Staphylococcus aureus","score_opus":0.029117540974268368,"score_gpt":0.38046015039419057,"score_spread":0.3513426094199222,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2327951769","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987233,0.009851711,0.0022222158,0.00004832471,0.000059494163,0.0003263033,0.000022291355,0.0000061178216,0.00023055446],"genre_scores_gemma":[0.99848115,0.0002449492,0.00091169693,0.00018176108,0.000028601187,0.00004181309,0.00006313481,0.000012134347,0.00003477652],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992318,0.00009398762,0.0002188621,0.00017300242,0.0000911708,0.00019118287],"domain_scores_gemma":[0.9995708,0.0000039515103,0.00007072867,0.00021936218,0.000044828117,0.00009031314],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002491792,0.00010768314,0.00011028478,0.00002853692,0.000024881485,0.000007898072,0.00008103502,0.00010001303,0.000022982947],"category_scores_gemma":[0.000037519883,0.00011433791,0.000039247647,0.00008332375,0.00008636709,0.000006425156,0.00005203898,0.000083567174,0.0000025566292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000067783134,0.00054369075,0.017056974,0.00002458054,0.000010953353,0.0000015168247,0.000106840744,0.000003136891,0.97488457,0.00008542436,0.000023006156,0.007191495],"study_design_scores_gemma":[0.0015080596,0.00009293403,0.0040571424,0.000003931261,0.000028163386,0.000007520715,0.00003900041,0.00007041589,0.9824073,0.000015149924,0.011653765,0.00011663248],"about_ca_topic_score_codex":0.000007645965,"about_ca_topic_score_gemma":0.000006022229,"teacher_disagreement_score":0.012999832,"about_ca_system_score_codex":0.00001137658,"about_ca_system_score_gemma":0.00002906018,"threshold_uncertainty_score":0.46625647},"labels":[],"label_agreement":null},{"id":"W2334943452","doi":"10.1021/je200789w","title":"Solubility of a Lysozyme in Polyelectrolyte Aqueous Solutions","year":2011,"lang":"en","type":"article","venue":"Journal of Chemical & Engineering Data","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Polyelectrolyte; Lysozyme; Aqueous solution; Solubility; Chemical engineering; Polymer chemistry; Organic chemistry; Polymer; Biochemistry","score_opus":0.04540806290158437,"score_gpt":0.2478076405966071,"score_spread":0.20239957769502273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2334943452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9834696,0.0022315516,0.013898674,0.00009910801,0.000072015784,0.000074190684,0.00005060865,0.0000051550956,0.000099088735],"genre_scores_gemma":[0.994194,0.00005286161,0.0056345207,0.000011826989,0.00006410857,0.0000014468905,0.000030609557,0.0000064171077,0.0000042544916],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992231,0.000017868117,0.0003769335,0.0001365767,0.00009741277,0.00014812159],"domain_scores_gemma":[0.99921066,0.000012423613,0.00011591267,0.0005246023,0.000070470734,0.00006594668],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046170145,0.000071924216,0.0001516617,0.00003970471,0.000006093754,0.0000030404215,0.00046765746,0.00008305891,0.000015507547],"category_scores_gemma":[0.0005573579,0.00006718952,0.000055801585,0.00008118304,0.000040061845,0.000010130108,0.00014831014,0.00015683008,5.223572e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007536213,0.00013178012,0.00043078366,0.000018966566,0.00002422016,0.0000017801985,0.000020714564,0.00001810388,0.9981661,0.00005650973,0.00010741548,0.00094826403],"study_design_scores_gemma":[0.0003467107,0.00008295136,0.0021682775,0.00001812468,0.000014206707,0.000042233456,0.0000041357184,0.0011678017,0.9938208,0.0001260708,0.0021198243,0.00008890143],"about_ca_topic_score_codex":0.000013146942,"about_ca_topic_score_gemma":0.0000013014031,"teacher_disagreement_score":0.010724347,"about_ca_system_score_codex":0.000017009768,"about_ca_system_score_gemma":0.00007574989,"threshold_uncertainty_score":0.2739909},"labels":[],"label_agreement":null},{"id":"W2339341826","doi":"10.1007/978-1-4939-3387-7_49","title":"Practical Approaches to Forced Degradation Studies of Vaccines","year":2016,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Forced degradation; Degradation (telecommunications); Stress (linguistics); Computer science; Biochemical engineering; Reliability engineering; Engineering; Mathematics; Statistics; Telecommunications","score_opus":0.20983502900770923,"score_gpt":0.4674554328271191,"score_spread":0.25762040381940987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2339341826","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11620292,0.0007349022,0.8800989,0.0024299657,0.00007207948,0.00028251205,0.0000058502687,0.000006735264,0.00016617871],"genre_scores_gemma":[0.28526747,0.00008805459,0.71424496,0.00015170906,0.000021504487,0.00010233623,0.000010159636,0.000009236387,0.00010455834],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99813443,0.0009382417,0.0003169437,0.00038326866,0.000047397996,0.00017973027],"domain_scores_gemma":[0.99922276,0.00013878175,0.00009423078,0.00041145718,0.000086527056,0.000046231373],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013285818,0.00011689511,0.00022471888,0.00007850493,0.000018618473,0.0000023731532,0.00014096248,0.00015612021,0.000008828469],"category_scores_gemma":[0.0039009587,0.000079619625,0.00006419277,0.00013737187,0.00011407264,0.0000026958157,0.00012970905,0.000045669985,0.000002182462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000088209694,0.00004407609,0.0024117897,0.000012780026,0.000037753805,5.419543e-7,0.000025858919,0.0000028490495,0.9434143,0.011414581,0.000025781655,0.042521536],"study_design_scores_gemma":[0.00034552946,0.00024335503,0.001117165,0.000008727337,0.000008150283,0.0000041582484,0.00006730122,0.000011257008,0.9867648,0.0060515967,0.0052626953,0.00011524985],"about_ca_topic_score_codex":0.0000041702483,"about_ca_topic_score_gemma":0.000011454793,"teacher_disagreement_score":0.16906455,"about_ca_system_score_codex":0.000017830587,"about_ca_system_score_gemma":0.000045524124,"threshold_uncertainty_score":0.46700937},"labels":[],"label_agreement":null},{"id":"W2342317773","doi":"10.1007/978-94-010-1015-3_213","title":"Microchip-Based Selective Preconcentration Using Protein A Immunoaffinity Chromatography","year":2001,"lang":"en","type":"book-chapter","venue":"","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Analyte; Chromatography; Immunoassay; Bead; Volume (thermodynamics); Materials science; Chemistry","score_opus":0.01704621429337544,"score_gpt":0.2393679914290998,"score_spread":0.22232177713572437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2342317773","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.054785036,0.0049414844,0.0348731,0.00014956918,0.00018789968,0.0045728283,0.00021129863,0.00016230169,0.9001165],"genre_scores_gemma":[0.88388246,0.00021457915,0.0066482644,0.00040557864,0.00037316585,0.00018021114,0.0015293238,0.00014272798,0.106623664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986322,0.000051528088,0.00034680055,0.00059805124,0.00014734447,0.00022410511],"domain_scores_gemma":[0.99887836,0.000005979079,0.0002495141,0.0005549467,0.00023214934,0.00007906995],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016600429,0.00032937306,0.00023847741,0.00007547319,0.00012827347,0.000039486586,0.00018968692,0.0005448947,0.000327238],"category_scores_gemma":[0.00002815858,0.00033611746,0.00024713652,0.000044494627,0.00013688566,0.0000037522475,0.00004008602,0.00021571228,0.000017665116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002955479,0.00014924195,0.00016454463,0.00010126985,0.00022628931,0.0000025018305,0.000021088772,0.000024166142,0.98828995,0.0064797164,0.00033749422,0.0039081597],"study_design_scores_gemma":[0.0009079444,0.00034957562,0.0001977184,0.0001151764,0.0000691071,0.000015354808,0.000008626623,0.0002214445,0.7194863,0.0031606792,0.27454594,0.0009221236],"about_ca_topic_score_codex":0.000033319575,"about_ca_topic_score_gemma":0.00006837054,"teacher_disagreement_score":0.82909745,"about_ca_system_score_codex":0.00005939767,"about_ca_system_score_gemma":0.00042582,"threshold_uncertainty_score":0.9999091},"labels":[],"label_agreement":null},{"id":"W2348529130","doi":"","title":"Optimization of Chromatographic Separation Operation for Xylose and Xylitol","year":2002,"lang":"en","type":"article","venue":"","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CAE (Canada)","funders":"","keywords":"Xylitol; Xylose; Chromatography; Chemistry; Chromatographic separation; Volumetric flow rate; Inlet; Simulated moving bed; Process engineering; Engineering; Mechanics; Organic chemistry; Mechanical engineering; High-performance liquid chromatography; Physics","score_opus":0.014480576581986348,"score_gpt":0.26406599040976,"score_spread":0.24958541382777363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2348529130","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4369546,0.0012437472,0.5588602,0.000377506,0.000041319425,0.00077063305,0.000019571218,0.000015812024,0.0017166195],"genre_scores_gemma":[0.98952824,0.00017850637,0.009893934,0.000051731302,0.000022210796,0.00004899119,0.00009293611,0.000003909096,0.00017956445],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996472,0.00001903559,0.000120351644,0.00013126558,0.000035231293,0.000046925874],"domain_scores_gemma":[0.99974537,0.0000041576363,0.000036221532,0.00012170894,0.00007213987,0.000020393882],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000084247884,0.000041336716,0.00004864473,0.000019304267,0.000037359445,0.000009330463,0.000028123897,0.000056975143,0.000045486853],"category_scores_gemma":[0.000040137475,0.000040089566,0.000022929398,0.00003448713,0.00003135638,0.000004388385,0.000008053098,0.000010025342,5.845677e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001007728,0.0002870343,0.0039927997,0.00012823909,0.00004681139,5.4146852e-8,0.00017997704,0.0054382323,0.9663083,0.0045243287,0.0013702384,0.017623223],"study_design_scores_gemma":[0.0013478742,0.000518774,0.0042478484,0.000006574767,0.000020771766,0.000004676712,0.00006415338,0.24274628,0.7398254,0.00023966673,0.010745627,0.00023235133],"about_ca_topic_score_codex":0.0000024344495,"about_ca_topic_score_gemma":0.000005870497,"teacher_disagreement_score":0.5525736,"about_ca_system_score_codex":0.0000017813417,"about_ca_system_score_gemma":0.000005100792,"threshold_uncertainty_score":0.1634805},"labels":[],"label_agreement":null},{"id":"W2383067422","doi":"","title":"Separation and characterization of conformational isomers of rhG-CSF","year":2000,"lang":"en","type":"article","venue":"","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CAE (Canada)","funders":"","keywords":"Sequence (biology); Chemistry; Biochemistry; Chromatography","score_opus":0.005873445604854429,"score_gpt":0.2427134649178537,"score_spread":0.23684001931299928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2383067422","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919547,0.000030526047,0.0015928482,0.000073552495,0.0000074177087,0.00008763306,0.000021356425,0.0000021835276,0.0062297992],"genre_scores_gemma":[0.9985071,0.00009564125,0.00020405883,0.00005317016,0.000007978384,0.000004056046,0.00026207225,0.0000014035818,0.0008645102],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997165,0.0000132689465,0.00013687206,0.00005945138,0.000043991527,0.00002991359],"domain_scores_gemma":[0.999807,0.000001852509,0.000046400874,0.000078825986,0.00005194866,0.000013990815],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006544626,0.00002907523,0.00004383539,0.000010989269,0.000011674831,0.0000024731987,0.000024205094,0.00003611307,0.00037350546],"category_scores_gemma":[0.000008124625,0.000026901876,0.000013590322,0.000025137038,0.000041903684,0.0000051003612,0.000004930781,0.0000095188025,0.000002459099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041068815,0.000022493734,0.0015017445,0.000014743494,0.000006010353,4.6804147e-9,0.000040528274,0.0000034447635,0.9867679,0.00079531554,0.000019379084,0.010787366],"study_design_scores_gemma":[0.000247964,0.00007603903,0.09749503,0.000002371476,0.0000031064744,0.0000011658088,0.000018801029,0.0004047042,0.88164824,0.00006273189,0.0199898,0.00005006564],"about_ca_topic_score_codex":0.000002772574,"about_ca_topic_score_gemma":0.0000011813213,"teacher_disagreement_score":0.10511968,"about_ca_system_score_codex":0.0000013102741,"about_ca_system_score_gemma":0.000017124772,"threshold_uncertainty_score":0.4089623},"labels":[],"label_agreement":null},{"id":"W2429788321","doi":"10.1385/0-89603-375-9:309","title":"Epitope Mapping of Protein Antigens by Expression-PCR (E-PCR)","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"","keywords":"Epitope; Molecular biology; Linear epitope; Immunoprecipitation; Biology; Epitope mapping; Monoclonal antibody; Amino acid; FLAG-tag; Cloning (programming); Gene; Biochemistry; Antigen; Antibody; Fusion protein; Recombinant DNA; Genetics","score_opus":0.03428841126700028,"score_gpt":0.25796120316692295,"score_spread":0.22367279189992267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2429788321","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8647783,0.021590104,0.0073993877,0.000029609966,0.00015485862,0.0016859702,0.0000881749,0.00005888257,0.10421475],"genre_scores_gemma":[0.99319714,0.00010388127,0.001372395,0.00004928436,0.00003681017,0.000089715846,0.000030894946,0.000018437666,0.0051014465],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988494,0.00015671185,0.00028764404,0.0003530871,0.00014169206,0.00021149796],"domain_scores_gemma":[0.9990839,0.0000060425195,0.00013689662,0.00060892757,0.00008883908,0.00007544062],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002453502,0.0001416909,0.000154719,0.000023892222,0.00009684338,0.000017270235,0.00021859094,0.00013185182,0.000042822532],"category_scores_gemma":[0.000098064214,0.00013540666,0.00008056211,0.000013769175,0.00011921241,0.0000028788,0.00006580869,0.00008541515,0.0000025591644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018590485,0.000058242043,0.00004138867,0.000055321794,0.000019459114,6.059393e-7,0.000112589456,9.888595e-7,0.9913709,0.0023908853,0.0010050212,0.0049259877],"study_design_scores_gemma":[0.00020401823,0.000034184322,0.00007476676,0.000016966267,0.000002903397,8.345237e-7,0.000023412655,0.0000022873164,0.653237,0.0001898373,0.34610736,0.00010645079],"about_ca_topic_score_codex":0.00002663315,"about_ca_topic_score_gemma":0.000004017788,"teacher_disagreement_score":0.34510234,"about_ca_system_score_codex":0.000006776695,"about_ca_system_score_gemma":0.00004037842,"threshold_uncertainty_score":0.55217236},"labels":[],"label_agreement":null},{"id":"W2440461123","doi":"10.1016/j.csbj.2016.06.001","title":"Application of the Protein Maker as a platform purification system for therapeutic antibody research and development","year":2016,"lang":"en","type":"article","venue":"Computational and Structural Biotechnology Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada","funders":"National Research Council Canada","keywords":"Fast protein liquid chromatography; Process development; Monoclonal antibody; Protein purification; Computer science; Workflow; Antibody; Chemistry; Chromatography; Biology; Process engineering; High-performance liquid chromatography; Engineering","score_opus":0.026260962986584393,"score_gpt":0.31441483691037087,"score_spread":0.2881538739237865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2440461123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9022619,0.0005985469,0.09373746,0.002859139,0.000031046704,0.00048699492,0.000009707312,0.000007429383,0.000007764101],"genre_scores_gemma":[0.9959674,0.000025467769,0.0038687792,0.000016885328,0.000028626591,0.000043860142,0.000012193429,0.000004498875,0.00003228738],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993132,0.000039150334,0.00021688906,0.00018557694,0.0001273749,0.00011784719],"domain_scores_gemma":[0.9994233,0.00002552927,0.00012962011,0.00012681988,0.00026316443,0.000031555173],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035606365,0.000070107664,0.00007671443,0.000054553697,0.00032195458,0.000016516493,0.00014160427,0.00015073703,0.0000013016114],"category_scores_gemma":[0.00005274948,0.000038299997,0.000020703763,0.00006724222,0.00034718213,0.0000067350447,0.000060680042,0.000096493866,6.346969e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001177399,0.000011024813,0.002616992,0.000038864564,0.000033101398,9.319217e-8,0.00003318544,0.0000053917793,0.8199538,0.036436472,0.0000055058936,0.14074782],"study_design_scores_gemma":[0.0012593202,0.0003541504,0.10895148,0.00006391577,0.000007702944,0.0004181727,0.00027843364,0.0007252425,0.80092454,0.07697439,0.009869539,0.00017312667],"about_ca_topic_score_codex":0.0000011741961,"about_ca_topic_score_gemma":0.0000010639571,"teacher_disagreement_score":0.1405747,"about_ca_system_score_codex":0.00002581053,"about_ca_system_score_gemma":0.0001024645,"threshold_uncertainty_score":0.24762468},"labels":[],"label_agreement":null},{"id":"W2441283041","doi":"10.5006/c2016-07182","title":"Bovine Serum Albumin Adsorption on AISI 316L in Phosphate-Buffered Saline Solutions","year":2016,"lang":"en","type":"article","venue":"","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Adsorption; Bovine serum albumin; Phosphate; Saline; Phosphate buffered saline; Chemistry; Albumin; Chromatography; Materials science; Biochemistry; Medicine; Internal medicine; Organic chemistry","score_opus":0.017691463473120287,"score_gpt":0.2505338832687164,"score_spread":0.2328424197955961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2441283041","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98013484,0.00039782145,0.009971747,0.0059310757,0.00011825279,0.00034117108,0.00006014273,0.000037271013,0.0030076483],"genre_scores_gemma":[0.9951399,0.00015403939,0.00022394196,0.00038470534,0.00006381662,0.000046194666,0.000058979334,0.000009909639,0.0039185015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990898,0.00006995693,0.0002091304,0.0003228832,0.000088123226,0.00022012323],"domain_scores_gemma":[0.99941343,0.000013911682,0.000042635173,0.000407014,0.000056345467,0.00006666219],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002568011,0.00010917528,0.00009353786,0.000037693262,0.00003615302,0.000008519185,0.000118498916,0.00012761561,0.0003211222],"category_scores_gemma":[0.000157567,0.00007556267,0.00005165876,0.00007753811,0.000054937977,0.0000043871482,0.00004831796,0.00004837748,0.00008265403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028138896,0.00034949902,0.006058659,0.0000069833122,0.000011462609,6.484795e-7,0.000010049696,0.000004739647,0.9688536,0.0036665716,0.0016423735,0.01911403],"study_design_scores_gemma":[0.0015833712,0.000489581,0.09112969,0.000020237349,0.000003982152,0.0000023179198,0.000022349694,0.000097951706,0.8506124,0.00079661235,0.05499422,0.00024728896],"about_ca_topic_score_codex":0.000032910564,"about_ca_topic_score_gemma":0.0002554823,"teacher_disagreement_score":0.1182412,"about_ca_system_score_codex":0.00003339042,"about_ca_system_score_gemma":0.00004473849,"threshold_uncertainty_score":0.35160628},"labels":[],"label_agreement":null},{"id":"W2483772178","doi":"10.1385/0-89603-386-4:77","title":"Activation of Rayon/Polyester Cloth for Protein Immobilization","year":2003,"lang":"en","type":"book-chapter","venue":"Humana Press eBooks","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Agarose; Polyester; Polymer; Cellulose; Immobilized enzyme; Chemical engineering; Materials science; Chromatography; Dextran; Chemistry; Yield (engineering); Organic chemistry; Composite material; Enzyme","score_opus":0.04727079159712954,"score_gpt":0.2699930269624946,"score_spread":0.22272223536536506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2483772178","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018639436,0.006630847,0.03626194,0.0000492035,0.00022411233,0.008027237,0.00028863613,0.000057794317,0.94659626],"genre_scores_gemma":[0.101395674,0.00019743886,0.001380688,0.0002457094,0.00032173021,0.0009950702,0.0010477996,0.00015481898,0.89426106],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99888176,0.000033495628,0.0003765208,0.0004306725,0.00013852114,0.0001390445],"domain_scores_gemma":[0.99875563,0.00000722454,0.00035336634,0.00060613645,0.00023496349,0.000042693693],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001713919,0.00022846478,0.00022703214,0.000045331028,0.00006241133,0.000016894262,0.00016610116,0.00040304408,0.000027955919],"category_scores_gemma":[0.00004647642,0.0002345658,0.0001549735,0.000003055944,0.00011469601,0.0000029616015,0.00004223211,0.00009257337,9.982915e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006566978,0.00012204707,0.0000024784586,0.0013188695,0.0003191196,4.238949e-7,0.00018547855,0.000016886375,0.43068555,0.50858164,0.0040533645,0.054057457],"study_design_scores_gemma":[0.00033319052,0.00013209946,0.000004353847,0.00005344029,0.000024144761,4.0642468e-7,0.000001976287,0.0000056647873,0.37127382,0.0033579716,0.62462616,0.00018675135],"about_ca_topic_score_codex":0.000009438599,"about_ca_topic_score_gemma":0.000009338014,"teacher_disagreement_score":0.6205728,"about_ca_system_score_codex":0.000020601943,"about_ca_system_score_gemma":0.000059937258,"threshold_uncertainty_score":0.9565316},"labels":[],"label_agreement":null},{"id":"W2491153247","doi":"10.1007/978-1-4939-4014-1_11","title":"Separation of Recombinant Therapeutic Proteins Using Capillary Gel Electrophoresis and Capillary Isoelectric Focusing","year":2016,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Isoelectric focusing; Capillary electrophoresis; Chromatography; Isoelectric point; Free-flow electrophoresis; Chemistry; Capillary action; Electrophoresis; Capillary electrochromatography; Peptide; Gel electrophoresis of proteins; Polyacrylamide gel electrophoresis; Materials science; Biochemistry; Enzyme","score_opus":0.023017702701757504,"score_gpt":0.380114681674928,"score_spread":0.3570969789731705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2491153247","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.45431843,0.007981925,0.53711027,0.00015157953,0.00005701001,0.00032787365,0.0000019820068,0.00000614477,0.000044814904],"genre_scores_gemma":[0.75893235,0.0013009794,0.23945937,0.00015324606,0.000027036089,0.00005235621,0.000011696937,0.000024518073,0.00003845615],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99739873,0.0013370129,0.0003928055,0.0004969152,0.00006550789,0.00030900814],"domain_scores_gemma":[0.9991716,0.00005864773,0.00017126785,0.000425095,0.00012263922,0.00005074593],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010809648,0.0001831422,0.00028317666,0.00014901604,0.00005344336,0.00000679698,0.00015441881,0.00029163717,0.000009063073],"category_scores_gemma":[0.00044653923,0.00013960319,0.00007828867,0.00022407006,0.00020016081,0.000004859566,0.000084499465,0.00009278375,4.7301245e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009638614,0.000049447004,0.003441605,0.000018511826,0.000034334385,0.0000016838904,0.000020148313,0.000002037658,0.9516433,0.0008765283,0.0000018678804,0.04381416],"study_design_scores_gemma":[0.0005025083,0.000397987,0.0015162553,0.00001546892,0.000017323937,0.000025397714,0.000009474419,0.0001585279,0.9890639,0.006578497,0.0015210198,0.00019361898],"about_ca_topic_score_codex":0.000056135028,"about_ca_topic_score_gemma":0.000013777971,"teacher_disagreement_score":0.30461392,"about_ca_system_score_codex":0.00004641805,"about_ca_system_score_gemma":0.0001207242,"threshold_uncertainty_score":0.5692853},"labels":[],"label_agreement":null},{"id":"W2519080622","doi":"10.1016/j.jchromb.2016.09.014","title":"High-resolution, preparative purification of PEGylated protein using a laterally-fed membrane chromatography device","year":2016,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Chromatography; Resolution (logic)","score_opus":0.013301422025105375,"score_gpt":0.25744254506844466,"score_spread":0.2441411230433393,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2519080622","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9881999,0.0014680009,0.009418383,0.00025973053,0.00008993085,0.00043739445,0.0000324084,0.00001403004,0.000080225116],"genre_scores_gemma":[0.9919074,0.00014934909,0.0077511054,0.000027626484,0.00009198597,0.00001711625,0.000011523474,0.000019365838,0.000024483947],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980336,0.00025377242,0.0008948896,0.0002687431,0.00032874392,0.00022029395],"domain_scores_gemma":[0.9974945,0.000019541818,0.0011205932,0.00042760346,0.00081003277,0.00012770966],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005736845,0.00020139305,0.0003517861,0.0002930158,0.0000833176,0.000021225862,0.0003083717,0.00018664046,0.00005944099],"category_scores_gemma":[0.00012260336,0.00014267411,0.00035988662,0.00047278788,0.0002414011,0.000037958216,0.000035491277,0.00009072584,0.000001920317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041514248,0.00020460921,0.0033612389,0.00006368803,0.0002378132,0.000002004876,0.000082764265,0.000018904471,0.99474627,0.00036528206,0.000078438155,0.00042381874],"study_design_scores_gemma":[0.0014728106,0.0005447161,0.017339287,0.00020543236,0.00005843878,0.000066834735,0.000035476238,0.00003358763,0.977258,0.0005927853,0.0021875456,0.00020506309],"about_ca_topic_score_codex":0.000020199843,"about_ca_topic_score_gemma":0.000007939324,"teacher_disagreement_score":0.017488275,"about_ca_system_score_codex":0.000022374827,"about_ca_system_score_gemma":0.00017919665,"threshold_uncertainty_score":0.58180815},"labels":[],"label_agreement":null},{"id":"W2520115209","doi":"10.1039/c6cp03867k","title":"Osmotic pressures of lysozyme solutions from gas-like to crystal states","year":2016,"lang":"en","type":"article","venue":"Physical Chemistry Chemical Physics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Nautical Research Society","funders":"","keywords":"Lysozyme; Ionic strength; Osmotic pressure; Chemistry; Crystal (programming language); Protein crystallization; Thermodynamics; Chemical physics; Ionic bonding; Crystallography; Materials science; Physical chemistry; Physics; Ion; Crystallization; Organic chemistry; Biochemistry; Aqueous solution; Computer science","score_opus":0.011792931509266488,"score_gpt":0.23858753367381888,"score_spread":0.22679460216455238,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2520115209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9877517,0.000116951014,0.010231982,0.00044128802,0.000027484735,0.00016459438,0.00057443226,0.00003532261,0.0006562036],"genre_scores_gemma":[0.99840885,0.000013613029,0.00034947577,0.00008474963,0.00053796574,0.000050153,0.00036094236,0.000025122657,0.00016912383],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99858814,0.00002792265,0.00025641115,0.0005452217,0.0002452503,0.00033705047],"domain_scores_gemma":[0.99874085,0.00007580133,0.000101272446,0.0006927771,0.00016190975,0.00022738495],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000055411594,0.0002244254,0.00026703352,0.0000051334764,0.00004312608,0.0000120520735,0.0003639224,0.000114345356,0.000048320144],"category_scores_gemma":[0.0001770339,0.00017914057,0.00019742861,0.0001051069,0.00025853288,0.0000088595,0.00024646882,0.00009975772,0.000021356263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009136001,0.00043383107,0.000096507225,0.00003917643,0.000056964764,2.6250402e-7,0.000048284906,0.000022113647,0.99643886,0.000084877676,0.0008417319,0.00184604],"study_design_scores_gemma":[0.00038913693,0.000035823967,0.00012551463,0.000024124647,0.000029248164,4.4852874e-7,0.000014345458,0.000102865,0.98532563,0.008906463,0.0048016976,0.00024467628],"about_ca_topic_score_codex":0.0000178442,"about_ca_topic_score_gemma":5.40724e-7,"teacher_disagreement_score":0.011113194,"about_ca_system_score_codex":0.000030131594,"about_ca_system_score_gemma":0.00006253637,"threshold_uncertainty_score":0.73051405},"labels":[],"label_agreement":null},{"id":"W2522213059","doi":"10.1016/j.chroma.2016.09.044","title":"Using a box instead of a column for process chromatography","year":2016,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Chromatography; Chemistry; Elution; Column chromatography; Countercurrent chromatography; Chromatography column; Two-dimensional chromatography; Resolution (logic); Packed bed; High-performance liquid chromatography; Computer science; Artificial intelligence","score_opus":0.02237478820971764,"score_gpt":0.3026890200037585,"score_spread":0.2803142317940409,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2522213059","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97387,0.0016942634,0.023756681,0.00011385385,0.000096290736,0.00029092195,0.000043640415,0.000005406604,0.00012895788],"genre_scores_gemma":[0.9942182,0.00012559457,0.0054740976,0.000043851385,0.00010004793,0.000015588557,0.0000021475978,0.000015095055,0.0000054344205],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988492,0.000054308763,0.0005600388,0.00016419587,0.00019720352,0.00017501679],"domain_scores_gemma":[0.9984373,0.00002470514,0.00065286487,0.00025056087,0.00053476874,0.00009978641],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042160312,0.00012375004,0.00027002848,0.00019953206,0.00005206836,0.000011984143,0.00024808495,0.00011989829,0.000013969351],"category_scores_gemma":[0.00014009955,0.00008698479,0.00046013363,0.00026982478,0.00018958842,0.000014838252,0.000020233267,0.00004611262,1.9928227e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034098522,0.00023953142,0.02533669,0.00017437039,0.00020752643,0.0000011821786,0.000069984984,0.0000024172434,0.97036165,0.00018309991,0.00024168774,0.0028408675],"study_design_scores_gemma":[0.0033654412,0.0012509868,0.0127053885,0.00030991033,0.00009566941,0.00017091272,0.00016789738,0.000023973933,0.9639261,0.0025340402,0.015173698,0.0002760236],"about_ca_topic_score_codex":0.000002210181,"about_ca_topic_score_gemma":0.0000032970656,"teacher_disagreement_score":0.020348158,"about_ca_system_score_codex":0.000007841952,"about_ca_system_score_gemma":0.00018620909,"threshold_uncertainty_score":0.35471368},"labels":[],"label_agreement":null},{"id":"W2527736092","doi":"10.1002/btpr.2376","title":"Recovery of functionally‐active protein from inclusion bodies using a thermal‐cycling method","year":2016,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"McMaster University","keywords":"Inclusion bodies; Temperature cycling; Enzyme; Chemistry; Escherichia coli; Heterologous; Cycling; Recombinant DNA; Biochemistry; Urea; Protein folding; Biophysics; Biology; Thermal; Gene","score_opus":0.016817719434300774,"score_gpt":0.286769518052169,"score_spread":0.2699517986178682,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2527736092","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94854134,0.002165607,0.04707285,0.0015075655,0.00008187635,0.00042787124,0.0000810711,0.000053107975,0.00006869999],"genre_scores_gemma":[0.95731133,0.00007044746,0.042328365,0.000032748874,0.00006363003,0.00007337592,0.000022795057,0.000015224,0.00008210248],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886626,0.00013567736,0.00025912002,0.00043300845,0.000121372505,0.00018453637],"domain_scores_gemma":[0.99911094,0.000025774807,0.0002257456,0.00048705903,0.00011948991,0.000030964653],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028984674,0.00014048946,0.00018050431,0.000075856165,0.00014260656,0.0000048385386,0.0002578871,0.000514808,0.00003066876],"category_scores_gemma":[0.00024467293,0.00010120967,0.00008437016,0.00007724918,0.00035818972,0.000008100398,0.00060415623,0.00009136033,0.0000034499585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027245298,0.00007476841,0.00082548254,0.000009024122,0.00006409292,6.909397e-7,0.000023988068,0.000002030316,0.8493343,0.00024389243,0.0000038296494,0.14914542],"study_design_scores_gemma":[0.0004052796,0.0001754158,0.0016393422,0.00005117674,0.00001397685,0.000002673628,0.000034752644,0.000037533544,0.9898866,0.002445995,0.005168353,0.00013890325],"about_ca_topic_score_codex":0.000026390988,"about_ca_topic_score_gemma":0.000010947227,"teacher_disagreement_score":0.14900652,"about_ca_system_score_codex":0.00003451764,"about_ca_system_score_gemma":0.00008037773,"threshold_uncertainty_score":0.41272104},"labels":[],"label_agreement":null},{"id":"W2534400021","doi":"10.1021/acs.iecr.6b03122","title":"Modeling and Optimization of Protein PEGylation","year":2016,"lang":"en","type":"article","venue":"Industrial & Engineering Chemistry Research","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"PEGylation; Polyethylene glycol; PEG ratio; Process (computing); Chemistry; Computer science; Process optimization; Biological system; Chemical engineering; Organic chemistry; Engineering; Biology","score_opus":0.067449709315164,"score_gpt":0.3124606476257949,"score_spread":0.2450109383106309,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2534400021","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9807759,0.00023069573,0.018258784,0.0002683074,0.000019013234,0.00026178636,0.000012610359,0.000014851291,0.0001580404],"genre_scores_gemma":[0.9991415,0.00003424994,0.00033506227,7.8222337e-7,0.00016792082,0.00003951041,0.00001603715,0.000010967357,0.00025396128],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99924415,0.000032254753,0.00016906702,0.00021303978,0.0001814668,0.00016004172],"domain_scores_gemma":[0.99949074,0.000017971148,0.000023115112,0.00022356577,0.00017916034,0.00006542694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005927996,0.00006882507,0.00007443487,0.000027730455,0.00003388959,0.000011971596,0.00010087023,0.00019038533,0.000026194588],"category_scores_gemma":[0.0010238105,0.000057766945,0.000021403874,0.00010140035,0.00005403644,0.0000056980693,0.0000658463,0.00011694401,5.9456534e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045056528,0.000013706066,0.000090320435,0.000026084343,0.0000073597193,1.4637475e-7,0.0000056143936,0.020804264,0.97677165,0.00002470194,0.000008430219,0.0022026938],"study_design_scores_gemma":[0.00046145776,0.00003433689,0.000011714524,0.000047945534,0.0000014858607,0.0000014466099,0.000009826953,0.039185002,0.95928293,0.000017658036,0.00087096996,0.00007523558],"about_ca_topic_score_codex":0.0000095931755,"about_ca_topic_score_gemma":2.1091871e-7,"teacher_disagreement_score":0.01838074,"about_ca_system_score_codex":0.000023302715,"about_ca_system_score_gemma":0.00007789413,"threshold_uncertainty_score":0.23556677},"labels":[],"label_agreement":null},{"id":"W2535482783","doi":"10.12665/j21.kamen","title":"Adenovirus Type 5 (Ad5) Chromatographic Purification Process at the 20 L Scale","year":2003,"lang":"en","type":"article","venue":"BioProcessing Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Chromatography; Process (computing); Chemistry; Computer science","score_opus":0.013930022326019621,"score_gpt":0.2719599314755031,"score_spread":0.2580299091494835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2535482783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9823648,0.013128724,0.0014265706,0.0005801616,0.00023354635,0.00015799789,0.000004590504,0.000018698052,0.0020849223],"genre_scores_gemma":[0.9978148,0.0002919329,0.0004249113,0.00020552884,0.00016557417,0.000014697166,0.000019163297,0.000017379627,0.0010460409],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891,0.00010583761,0.00026361027,0.00026676612,0.00022247618,0.00023128728],"domain_scores_gemma":[0.99905,0.0000056873646,0.00021188447,0.00031927327,0.00030535323,0.00010775242],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062136503,0.00013313071,0.000095040756,0.000042029078,0.00065628573,0.00012933284,0.00025711607,0.00012860133,0.00011638311],"category_scores_gemma":[0.00018920453,0.0000930093,0.00007099817,0.00028674223,0.00018253854,0.000011979876,0.000021767495,0.00017538773,0.000028168488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013323357,0.00017818157,0.03340181,0.00006490666,0.0000451,0.0000022470015,0.00024619166,0.00003116194,0.9558694,0.000069838185,0.0015555231,0.008402416],"study_design_scores_gemma":[0.0006511514,0.00015634413,0.012754089,0.000040966657,0.000037064994,0.0007732331,0.00044907146,0.00004016743,0.7625985,0.0010934924,0.22104515,0.0003607189],"about_ca_topic_score_codex":0.0000011301019,"about_ca_topic_score_gemma":0.000011056805,"teacher_disagreement_score":0.21948963,"about_ca_system_score_codex":0.000026401423,"about_ca_system_score_gemma":0.00024014743,"threshold_uncertainty_score":0.50476855},"labels":[],"label_agreement":null},{"id":"W2565343891","doi":"10.1208/s12249-016-0688-7","title":"Lyophilization of an Adjuvanted Mycobacterium tuberculosis Vaccine in a Single-Chamber Pharmaceutical Cartridge","year":2016,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Duoject Medical Systems (Canada)","funders":"Bill and Melinda Gates Foundation","keywords":"Cartridge; Vial; Adjuvant; Freeze-drying; Chromatography; Materials science; Chemistry; Medicine; Immunology","score_opus":0.019453618925420746,"score_gpt":0.2906240334917392,"score_spread":0.27117041456631846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2565343891","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99646634,0.00036709252,0.0018269412,0.0005806656,0.000094120594,0.00030142354,0.00007400832,0.000023269624,0.00026614804],"genre_scores_gemma":[0.9991237,0.00017773634,0.00020420829,0.00015156982,0.00008275103,0.000038349437,0.000106801286,0.000017957433,0.00009690731],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880296,0.00012725478,0.00033217997,0.0003863277,0.00013529314,0.00021598989],"domain_scores_gemma":[0.99925566,0.000018091909,0.000079411904,0.00040602495,0.00013884457,0.000101964615],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030414504,0.00013818516,0.00016311597,0.00008135492,0.000023624852,0.000008085018,0.00012495626,0.00013653761,0.00013116753],"category_scores_gemma":[0.00016623495,0.000107255255,0.000058598893,0.00021700634,0.000057108413,0.00001679962,0.00006442866,0.00005993659,0.000008347762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023682525,0.00030519578,0.009480127,0.000024478017,0.000014189704,0.0000021964356,0.000027341437,0.0000017275795,0.97310853,0.000052693144,0.00004703304,0.016699636],"study_design_scores_gemma":[0.0017049268,0.0001598338,0.021661596,0.000022826414,0.000013005042,0.00001300249,0.000009220845,0.0001228967,0.96495616,0.000085337044,0.011089739,0.00016144363],"about_ca_topic_score_codex":0.000013147057,"about_ca_topic_score_gemma":0.000028931028,"teacher_disagreement_score":0.016538193,"about_ca_system_score_codex":0.000031648127,"about_ca_system_score_gemma":0.000037656766,"threshold_uncertainty_score":0.43737423},"labels":[],"label_agreement":null},{"id":"W2578900665","doi":"10.4155/bio-2016-0269","title":"Particle Sizing Methods for The Detection of Protein Aggregates in Biopharmaceuticals","year":2017,"lang":"en","type":"review","venue":"Bioanalysis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; University of British Columbia","keywords":"Sizing; Dispersion (optics); Characterization (materials science); Pharmaceutical industry; Biochemical engineering; Nanotechnology; Protein aggregation; Particle (ecology); Dynamic light scattering; Chemistry; Computer science; Materials science; Biotechnology; Physics; Biology; Nanoparticle; Engineering; Optics","score_opus":0.18018361111307774,"score_gpt":0.49973721510596897,"score_spread":0.31955360399289123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2578900665","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000063841867,0.9907566,0.008095241,0.00004539342,0.000033234075,0.0010192647,0.00002443249,0.0000038401176,0.000015656344],"genre_scores_gemma":[0.008819489,0.9882919,0.0019341076,0.000005658369,0.00004623777,0.0007262678,0.000023943878,0.00001341174,0.00013895928],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99863887,0.00037443035,0.00045994364,0.00031632843,0.000060946757,0.00014949143],"domain_scores_gemma":[0.99860096,0.00010676731,0.00043170634,0.0007440462,0.00007997249,0.000036530546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015010072,0.00015208275,0.00056088803,0.000052824318,0.00009389461,0.00002655851,0.00034089145,0.00019756866,0.0000068751156],"category_scores_gemma":[0.001136951,0.000098286546,0.0005314253,0.00017434922,0.00012665996,0.000002218614,0.000068178975,0.00008520769,0.000001546978],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010039327,0.00002667418,0.000005903741,0.00092703116,0.00021275187,6.2996335e-8,0.0000034862073,3.8352127e-7,0.0014495146,0.000016981203,2.2520108e-8,0.9973472],"study_design_scores_gemma":[0.00010277327,0.000028477114,0.000008092676,0.00020387545,0.0005838625,5.047737e-7,0.00000754986,0.00021406422,0.012741838,0.00003366495,0.98596495,0.00011035206],"about_ca_topic_score_codex":0.000027923086,"about_ca_topic_score_gemma":0.000039963576,"teacher_disagreement_score":0.9972368,"about_ca_system_score_codex":0.000020601201,"about_ca_system_score_gemma":0.00007879613,"threshold_uncertainty_score":0.40080088},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"not_applicable","genre":"review","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":[],"domain":null,"study_design":"design_other","genre":"review","about_ca_system":false,"about_ca_topic":false,"confidence":"low"}],"label_agreement":"split"},{"id":"W2584023351","doi":"10.1016/j.ijpharm.2017.01.060","title":"Effects of storage conditions on the stability of spray dried, inhalable bacteriophage powders","year":2017,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":106,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Health and Medical Research Council; National Institute of Allergy and Infectious Diseases; Australian Research Council; University of Sydney","keywords":"Spray drying; Pharmaceutical technology; Bacteriophage; Materials science; Chemistry; Chemical engineering; Chromatography; Engineering","score_opus":0.028034409472831638,"score_gpt":0.3443049652811575,"score_spread":0.31627055580832586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2584023351","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969498,0.00023085848,0.00035410412,0.0010951861,0.00054908136,0.00014712712,0.00007648986,0.0000012958708,0.0005960768],"genre_scores_gemma":[0.99938613,0.0001805209,0.0001074036,0.00014509498,0.000119816104,0.0000034927714,0.000007519598,0.000006061195,0.000043958913],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990786,0.00011190079,0.00034984108,0.00009268039,0.00028937453,0.000077633136],"domain_scores_gemma":[0.9982296,0.00009690664,0.00073106936,0.00028792382,0.0006026339,0.00005182588],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054373645,0.000077380515,0.00012501216,0.00003674058,0.00007241193,0.000026082806,0.0006436426,0.000051916733,0.00010780854],"category_scores_gemma":[0.00083480467,0.000058895737,0.00012957786,0.000018703353,0.00025821297,0.000014604009,0.00008005101,0.0001469531,0.0000017090226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023023978,0.00025599703,0.0030451263,0.000029161134,0.00016903614,0.000005226564,0.00009408852,0.000021558055,0.99490565,0.00056227116,0.00010744179,0.00057421677],"study_design_scores_gemma":[0.00076097465,0.00011068631,0.017016923,0.00002961197,0.000026197251,0.000009032607,0.000051293202,0.000024802022,0.97519547,0.00019208103,0.006534125,0.000048834743],"about_ca_topic_score_codex":0.0000043982704,"about_ca_topic_score_gemma":0.0000021969456,"teacher_disagreement_score":0.0197102,"about_ca_system_score_codex":0.000027014568,"about_ca_system_score_gemma":0.000111826244,"threshold_uncertainty_score":0.24016984},"labels":[],"label_agreement":null},{"id":"W2588550827","doi":"10.1016/j.jpba.2017.01.058","title":"Assessment of the structure of pegylated-recombinant protein therapeutics by the NMR fingerprint assay","year":2017,"lang":"en","type":"article","venue":"Journal of Pharmaceutical and Biomedical Analysis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Health Canada","funders":"Genentech; Amgen","keywords":"Chemistry; PEGylation; PEG ratio; Polyethylene glycol; Filgrastim; Recombinant DNA; Pegylated interferon; Pharmacology; Biochemistry; Toxicity; Organic chemistry","score_opus":0.017526369812388795,"score_gpt":0.34476080401381026,"score_spread":0.32723443420142145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2588550827","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883532,0.0010431691,0.0031526503,0.00714317,0.00007970883,0.00013552606,0.000044054377,8.864069e-7,0.00004764061],"genre_scores_gemma":[0.99922734,0.0002618172,0.00025052327,0.00013745825,0.00004827785,0.0000010375519,0.000004795113,0.0000034001544,0.0000653698],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986384,0.0002286417,0.00048628374,0.00013314774,0.00039248762,0.00012104645],"domain_scores_gemma":[0.99866164,0.00003439241,0.0006305506,0.00037134462,0.00019742275,0.00010462404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008817178,0.00009903287,0.00027054615,0.000036004338,0.00015815315,0.000026532056,0.0005423126,0.000114613846,0.00006927531],"category_scores_gemma":[0.00017590146,0.000044022694,0.00029086214,0.00013991963,0.00073169323,0.0000052063697,0.0001670513,0.000269244,6.7765356e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052899803,0.00024367054,0.018004877,0.000032248223,0.0010438778,6.289658e-7,0.000021811287,0.0000039530987,0.961575,0.00014035779,0.000068283356,0.018812409],"study_design_scores_gemma":[0.0012763073,0.00039491258,0.19685459,0.0000426982,0.0017784045,0.000020702797,0.000078872916,0.0039835954,0.75319296,0.0009447209,0.041256577,0.00017564508],"about_ca_topic_score_codex":0.000013306085,"about_ca_topic_score_gemma":0.0000058778433,"teacher_disagreement_score":0.20838201,"about_ca_system_score_codex":0.000010126151,"about_ca_system_score_gemma":0.000093952825,"threshold_uncertainty_score":0.2695954},"labels":[],"label_agreement":null},{"id":"W2595818559","doi":"10.3934/bioeng.2017.2.223","title":"Impact of operating conditions on chromatographic column performance: experimental studies on adsorption of high-value minor whey proteins","year":2017,"lang":"en","type":"article","venue":"AIMS bioengineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland; Western University","funders":"","keywords":"Chemistry; Adsorption; Van Deemter equation; Chromatography; Breakthrough curve; Volumetric flow rate; Ion chromatography; Ion exchange; Particle (ecology); Expanded bed adsorption; Porosity; Analytical Chemistry (journal); Ion; Elution; High-performance liquid chromatography; Organic chemistry; Thermodynamics","score_opus":0.021117524773148464,"score_gpt":0.31630403951168734,"score_spread":0.29518651473853885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2595818559","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99901664,0.00030047577,0.00007334463,0.000019110525,0.000096328586,0.0003481181,0.00005171849,0.000011997534,0.0000822597],"genre_scores_gemma":[0.9993932,0.000053220236,0.0003431903,0.000008400322,0.00004656576,0.00009097212,0.00003583605,0.000012148024,0.000016461854],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993353,0.000018995599,0.00022417802,0.0001944355,0.00010372096,0.00012337568],"domain_scores_gemma":[0.9992606,0.0000054909506,0.00015232747,0.0004667366,0.00007668181,0.000038178365],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012595061,0.00012655296,0.00016830799,0.000054000255,0.00012839428,0.0000152192715,0.00015067607,0.00007032169,0.0000089222585],"category_scores_gemma":[0.00009928359,0.000113376555,0.000096638134,0.000036729587,0.00012566749,0.000010662213,0.00004719251,0.000059546415,0.0000016160402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035534067,0.00013220422,0.005562003,0.000062466745,0.00009224367,1.7141967e-7,0.00008977297,0.0045947786,0.9889603,0.00035091993,0.00001394834,0.00010560392],"study_design_scores_gemma":[0.00038226874,0.0011791962,0.11474296,0.00009045403,0.0000067777346,0.000001505522,0.00006905671,0.0010644828,0.8823354,0.0000054161333,0.00001435879,0.00010810601],"about_ca_topic_score_codex":0.000044804627,"about_ca_topic_score_gemma":0.000003592818,"teacher_disagreement_score":0.10918096,"about_ca_system_score_codex":0.000026709891,"about_ca_system_score_gemma":0.000029626033,"threshold_uncertainty_score":0.46233618},"labels":[],"label_agreement":null},{"id":"W2603481122","doi":"10.1016/j.heliyon.2017.e00264","title":"The stability of insulin solutions in syringes is improved by ensuring lower molecular weight silicone lubricants are absent","year":2017,"lang":"en","type":"article","venue":"Heliyon","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Silicone; Silicone oil; Lubricant; Syringe; Denaturation (fissile materials); Chemistry; Materials science; Chromatography; Chemical engineering; Polymer chemistry; Organic chemistry; Nuclear chemistry; Medicine","score_opus":0.016704713726153512,"score_gpt":0.2532656689381005,"score_spread":0.23656095521194698,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2603481122","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9855296,0.012005509,0.00016687588,0.0014110589,0.00009431093,0.00028973253,0.00007841095,0.0000066687007,0.00041781465],"genre_scores_gemma":[0.9976959,0.0020248555,0.00005313927,0.00006358542,0.000020349727,0.0000474282,0.00001027138,0.00000952696,0.000074931486],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898,0.000077826255,0.000271321,0.00032102357,0.000114147486,0.0002356914],"domain_scores_gemma":[0.9985157,0.000016448534,0.0002074995,0.0010903596,0.00011292386,0.000057020734],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004164658,0.00011248092,0.00013651935,0.000014216695,0.00023827766,0.000031894575,0.00033808785,0.00010871983,0.000016702297],"category_scores_gemma":[0.00035070203,0.000091981936,0.00007618443,0.000033770688,0.00022393858,0.0000052734163,0.00018121049,0.00010389984,0.0000032212702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000079932244,0.00016296846,0.013151127,0.000056445868,0.00002006283,7.077905e-7,0.000043682037,9.893743e-7,0.9827196,0.000030368852,0.000055587137,0.0036785377],"study_design_scores_gemma":[0.00040356597,0.000051613933,0.09067921,0.000031892327,0.000005568357,7.6952585e-7,0.0000544505,0.000062441264,0.898586,0.00004129096,0.009963073,0.0001201282],"about_ca_topic_score_codex":0.00006947371,"about_ca_topic_score_gemma":0.00020379892,"teacher_disagreement_score":0.0841336,"about_ca_system_score_codex":0.00002745715,"about_ca_system_score_gemma":0.000049620703,"threshold_uncertainty_score":0.37509146},"labels":[],"label_agreement":null},{"id":"W2604428127","doi":"10.1208/s12249-017-0768-3","title":"Effects of Chamber Pressure and Partial Pressure of Water Vapor on Secondary Drying in Lyophilization","year":2017,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Privy Council Office","funders":"Pfizer Pharmaceuticals","keywords":"Vapor pressure; Vapour pressure of water; Water vapor; Partial pressure; Water content; Chemistry; Moisture; Aqueous solution; Chamber pressure; Chemical engineering; Analytical Chemistry (journal); Chromatography; Materials science; Organic chemistry; Oxygen","score_opus":0.008222005264280689,"score_gpt":0.26222361968914226,"score_spread":0.2540016144248616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2604428127","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976186,0.0012769962,0.000104503255,0.0001104362,0.00006887969,0.0003532897,0.000021050491,0.0000041800427,0.0004420262],"genre_scores_gemma":[0.99953425,0.00008446788,0.000036850306,0.00003087646,0.000038028254,0.000029506426,0.000023972754,0.0000075434878,0.000214476],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993759,0.000050242114,0.00016150216,0.00022197198,0.000082900864,0.00010753151],"domain_scores_gemma":[0.99945945,0.0000095675205,0.00010089881,0.00035271852,0.000047677688,0.00002969332],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020446062,0.000080944395,0.0001246324,0.000027428401,0.000052955806,0.000011480173,0.00011189521,0.00010650273,0.000021677839],"category_scores_gemma":[0.00010521857,0.00006483384,0.000028933957,0.000015973264,0.000096705786,0.000008694703,0.00008521811,0.00006726094,6.5685475e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013941238,0.00010638688,0.005433519,0.0003368455,0.00003338976,0.0000011119004,0.00014403668,0.000017951474,0.9898737,0.00009235626,0.00002802835,0.0037932468],"study_design_scores_gemma":[0.0007515501,0.00008964692,0.031884186,0.00002504848,0.000021957934,9.84095e-7,0.0000033974634,0.00011257469,0.9590458,0.00011272258,0.007881445,0.00007064532],"about_ca_topic_score_codex":0.000020677217,"about_ca_topic_score_gemma":0.000004193041,"teacher_disagreement_score":0.030827874,"about_ca_system_score_codex":0.0000014954663,"about_ca_system_score_gemma":0.000016683585,"threshold_uncertainty_score":0.26438472},"labels":[],"label_agreement":null},{"id":"W2605341073","doi":"10.1016/j.jpba.2017.03.063","title":"Application of 2D-NMR with room temperature NMR probes for the assessment of the higher order structure of filgrastim","year":2017,"lang":"en","type":"article","venue":"Journal of Pharmaceutical and Biomedical Analysis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"National Institute of Standards and Technology; U.S. Food and Drug Administration; National Institutes of Health","keywords":"Chemistry; Heteronuclear molecule; Nuclear magnetic resonance spectroscopy; Two-dimensional nuclear magnetic resonance spectroscopy; Biosimilar; Analytical Chemistry (journal); Proton NMR; Fluorine-19 NMR; Transverse relaxation-optimized spectroscopy; Chemometrics; Nuclear magnetic resonance; Biological system; Chromatography; Stereochemistry","score_opus":0.012624269195941734,"score_gpt":0.33886693346228897,"score_spread":0.32624266426634724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2605341073","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9552381,0.0011966157,0.033843964,0.009108666,0.000057478446,0.00036352326,0.0001670936,0.0000010928803,0.000023484678],"genre_scores_gemma":[0.99797076,0.00012149399,0.0016923597,0.00007053227,0.00008971895,0.0000047397352,0.000011958819,0.000003116128,0.000035290836],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99909735,0.00005666589,0.0003559306,0.00012056526,0.0002879231,0.000081587896],"domain_scores_gemma":[0.99866456,0.00004455326,0.00052952004,0.0002820556,0.00040650848,0.00007277816],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033700047,0.00008121471,0.00024539858,0.00003409681,0.000105600506,0.000013160233,0.00033533684,0.000100386605,0.000041076608],"category_scores_gemma":[0.00010505409,0.000033627843,0.00017568159,0.00017809814,0.00053156185,0.0000054235966,0.00006418269,0.00014066878,1.4298997e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027570123,0.0002848349,0.042869296,0.00014863056,0.001514339,2.2034045e-7,0.000021650552,0.00009141977,0.94449973,0.00033566475,0.00014388721,0.0098146275],"study_design_scores_gemma":[0.0020613642,0.0006437626,0.51284236,0.00004614239,0.0031887614,0.000011168377,0.00008169192,0.00869178,0.44089645,0.0005643924,0.030813945,0.00015818351],"about_ca_topic_score_codex":0.000007681856,"about_ca_topic_score_gemma":0.000009919755,"teacher_disagreement_score":0.5036033,"about_ca_system_score_codex":0.000005015108,"about_ca_system_score_gemma":0.0000867542,"threshold_uncertainty_score":0.19585617},"labels":[],"label_agreement":null},{"id":"W2608903237","doi":"10.1016/j.jchromb.2017.04.036","title":"Preparative separation of monoclonal antibody aggregates by cation-exchange laterally-fed membrane chromatography","year":2017,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; National Research Council Canada; University of Manitoba; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; McMaster University","keywords":"Chemistry; Chromatography; Elution; Chinese hamster ovary cell; Monomer; Monoclonal antibody; Membrane; Derivatization; High-performance liquid chromatography; Size-exclusion chromatography; Antibody; Biochemistry; Polymer; Organic chemistry","score_opus":0.009709882577664457,"score_gpt":0.3084365918679694,"score_spread":0.2987267092903049,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2608903237","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99224687,0.004866894,0.0012472242,0.0002622873,0.00015515719,0.00025496408,0.00007003943,0.0000073625447,0.00088922266],"genre_scores_gemma":[0.99723864,0.0014310346,0.0009977549,0.000041454172,0.00011335133,0.000012255499,0.00010630475,0.0000143533325,0.00004487828],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99857086,0.00010967075,0.00062347547,0.00022849282,0.0002914851,0.00017598904],"domain_scores_gemma":[0.9973201,0.000015612051,0.0014957018,0.0005679841,0.0004846302,0.00011598148],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044375105,0.00018428931,0.0003276409,0.00015412754,0.00021007685,0.000078277444,0.00047048728,0.00015592588,0.00004193664],"category_scores_gemma":[0.00009358627,0.00016061979,0.00036689034,0.000117083706,0.00029267557,0.000052038453,0.00004997401,0.00010949701,0.0000015221041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029796938,0.0002831831,0.049402528,0.00008178911,0.00032673328,0.0000025408192,0.00028040772,0.0000060921448,0.94686514,0.00009035019,0.0016263769,0.00073688093],"study_design_scores_gemma":[0.0012798778,0.00069787353,0.09996253,0.00007902204,0.00005969578,0.00005297189,0.000056873272,0.000054649743,0.88103974,0.0003846852,0.016098557,0.00023352778],"about_ca_topic_score_codex":0.000036262336,"about_ca_topic_score_gemma":0.0000166348,"teacher_disagreement_score":0.06582542,"about_ca_system_score_codex":0.000008203635,"about_ca_system_score_gemma":0.000095166775,"threshold_uncertainty_score":0.65498847},"labels":[],"label_agreement":null},{"id":"W2625012239","doi":"10.1177/1533034617714149","title":"Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics","year":2017,"lang":"en","type":"article","venue":"Technology in Cancer Research & Treatment","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Ministry of Education, India; Ministry of Earth Sciences; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Chemistry; Differential scanning calorimetry; Differential pulse voltammetry; Chromatography; Fluorescence spectroscopy; Urea; Immunoglobulin G; Thermal stability; Fluorescence; Analytical Chemistry (journal); Biophysics; Biochemistry; Antibody; Cyclic voltammetry; Electrochemistry; Electrode; Biology; Organic chemistry; Immunology","score_opus":0.10508567141437604,"score_gpt":0.43783850171368843,"score_spread":0.3327528302993124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2625012239","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965545,0.0003612933,0.00071312033,0.00010965873,0.000024925572,0.002054325,0.00015717029,0.000011897913,0.000013089191],"genre_scores_gemma":[0.99835265,0.00015176662,0.0009941421,0.0000010545606,0.000014106246,0.00044740972,0.000016147744,0.00001678776,0.000005958894],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99819684,0.0003010987,0.00043382932,0.00049447885,0.00018608641,0.00038768054],"domain_scores_gemma":[0.99829066,0.00005614188,0.0002622846,0.001010858,0.0003490205,0.00003105311],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009711162,0.00016783632,0.00037210915,0.00021731084,0.00016983444,0.000012140663,0.00029730043,0.00031613326,0.000007951542],"category_scores_gemma":[0.00025890954,0.00015384742,0.00008657341,0.00019487622,0.0009483968,0.00000954347,0.00011519749,0.00015847417,2.5442898e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013951029,0.00056798704,0.094800085,0.000071923576,0.000036935402,0.0000013043594,0.00007179712,0.000010953221,0.87153304,0.000007707613,2.1230402e-8,0.031503163],"study_design_scores_gemma":[0.0017200605,0.0010474536,0.061279774,0.000069547714,0.000012004189,5.369545e-7,0.00013883277,0.0023487364,0.9330792,0.0001834742,0.0000146736065,0.00010571369],"about_ca_topic_score_codex":0.0041019754,"about_ca_topic_score_gemma":0.0021340877,"teacher_disagreement_score":0.061546173,"about_ca_system_score_codex":0.0004977049,"about_ca_system_score_gemma":0.0004937862,"threshold_uncertainty_score":0.62737155},"labels":[],"label_agreement":null},{"id":"W2740601555","doi":"10.1016/j.chroma.2017.07.088","title":"Mathematical modelling and evaluation of performance of cuboid packed-bed devices for chromatographic separations","year":2017,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Cuboid; Packed bed; Chromatography; Chemistry; Elution; Column (typography); Volume (thermodynamics); Analytical Chemistry (journal); Structural engineering; Mathematics; Engineering; Geometry; Thermodynamics","score_opus":0.04220731038782835,"score_gpt":0.32547165349210644,"score_spread":0.28326434310427806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2740601555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98937994,0.0017506061,0.008290717,0.00005928224,0.000032729284,0.00026474905,0.000013197395,0.0000015745957,0.00020721908],"genre_scores_gemma":[0.9936207,0.0003394475,0.0059696427,0.0000056256326,0.000035416717,0.000015963371,0.0000051795723,0.0000064513297,0.0000016072618],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990211,0.000052491294,0.00048093873,0.00010588224,0.00025355085,0.00008600273],"domain_scores_gemma":[0.99805665,0.000022236769,0.0008509945,0.00031283175,0.00070675334,0.000050524544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012001093,0.000083442384,0.00022042618,0.0001044395,0.00012166099,0.000022202374,0.00018512023,0.00008079134,0.000005859194],"category_scores_gemma":[0.00011569145,0.00007012677,0.00018465043,0.000055389697,0.00020737168,0.000024964327,0.000021948641,0.000046064793,8.595421e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008740846,0.0012642378,0.12299781,0.0021988726,0.0010494513,4.988971e-7,0.0008057443,0.0017707194,0.85383594,0.006613302,0.00013649838,0.00845282],"study_design_scores_gemma":[0.0047548846,0.0022910582,0.10392628,0.00054989156,0.000691617,0.00010079462,0.00033981973,0.068260126,0.80299765,0.014187357,0.0014964503,0.00040406358],"about_ca_topic_score_codex":0.0000013067602,"about_ca_topic_score_gemma":0.000003746773,"teacher_disagreement_score":0.066489406,"about_ca_system_score_codex":0.0000030882782,"about_ca_system_score_gemma":0.000094888164,"threshold_uncertainty_score":0.28596866},"labels":[],"label_agreement":null},{"id":"W2763008197","doi":"10.1007/s00249-017-1259-x","title":"Allowance for radial dilution in evaluating the concentration dependence of sedimentation coefficients for globular proteins","year":2017,"lang":"en","type":"article","venue":"European Biophysics Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Alberta; University of Lethbridge","funders":"Biotechnology and Biological Sciences Research Council; Natural Sciences and Engineering Research Council of Canada","keywords":"Allowance (engineering); Dilution; Globular cluster; Globular protein; Sedimentation; Chemistry; Physics; Chromatography; Analytical Chemistry (journal); Thermodynamics; Crystallography; Biology; Astrophysics; Engineering; Paleontology","score_opus":0.04520469634902247,"score_gpt":0.3443669113036401,"score_spread":0.29916221495461764,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2763008197","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8246179,0.00013011637,0.17393096,0.00021470505,0.00017317015,0.0008004242,0.000027629581,0.0000018659479,0.00010321605],"genre_scores_gemma":[0.99683523,0.000025103876,0.0027351086,0.00003842254,0.00027223193,0.000027972683,0.00003600777,0.000008680234,0.000021251231],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922067,0.00014482083,0.0002373181,0.00014874195,0.00013116523,0.00011725597],"domain_scores_gemma":[0.99910975,0.000013225506,0.0003973022,0.00024163185,0.00021159294,0.000026518182],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011776506,0.000066404544,0.000066618915,0.0000081263815,0.00035891923,0.00006851287,0.00025983623,0.000023746146,7.7788087e-7],"category_scores_gemma":[0.00043503326,0.000053661493,0.00006597513,0.000021079024,0.00008850211,0.000015325637,0.000028530443,0.000060001796,6.818524e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028245183,0.00006910446,0.0015379883,0.000015802092,0.000012007639,2.0144273e-7,0.000109289846,0.00045195658,0.9766519,0.00036732393,0.000020414744,0.020481529],"study_design_scores_gemma":[0.004630593,0.0014210442,0.06998278,0.00008062555,0.000036923066,0.000008128231,0.00016357412,0.015434582,0.90431505,0.0013803457,0.0023007677,0.00024556284],"about_ca_topic_score_codex":0.000003032161,"about_ca_topic_score_gemma":0.0000023858872,"teacher_disagreement_score":0.17221731,"about_ca_system_score_codex":0.000021184722,"about_ca_system_score_gemma":0.00007355003,"threshold_uncertainty_score":0.2760553},"labels":[],"label_agreement":null},{"id":"W2771693455","doi":"10.1016/j.jchromb.2017.12.003","title":"Rapid preparative separation of monoclonal antibody charge variants using laterally-fed membrane chromatography","year":2017,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Chromatography; Monoclonal antibody; Isoelectric focusing; Ion chromatography; Fragmentation (computing); Membrane; Antibody; Analytical Chemistry (journal); Biochemistry","score_opus":0.022104384377732333,"score_gpt":0.3272552599654639,"score_spread":0.3051508755877316,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2771693455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949685,0.0016126211,0.0019443964,0.00007100588,0.00023657427,0.00024571363,0.00004064157,0.0000062625472,0.00087431195],"genre_scores_gemma":[0.99632484,0.00057127647,0.0028453888,0.000032358974,0.0001647906,0.000004066132,0.00002865785,0.00001606012,0.000012561574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99837476,0.00014753266,0.0007134721,0.00024668232,0.00030911714,0.00020844316],"domain_scores_gemma":[0.9972618,0.000011850135,0.0015265613,0.0006230884,0.0004516971,0.00012498698],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006157898,0.00019892867,0.00039743376,0.00020494567,0.00024724813,0.00007922615,0.0004729323,0.00017146273,0.00006594963],"category_scores_gemma":[0.0000916288,0.00017427692,0.00046808948,0.00012919554,0.00024661075,0.000058502897,0.000062804815,0.00012954875,0.0000013449829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048712466,0.00023115425,0.020399682,0.000053647134,0.0003499336,0.000006193809,0.00016489938,0.000009952896,0.97780305,0.00011615693,0.000109243214,0.00026896942],"study_design_scores_gemma":[0.001772167,0.00072792516,0.18115851,0.00010922413,0.00009160769,0.00015886413,0.00004321636,0.00037196284,0.8122382,0.0003186938,0.0027347794,0.00027480093],"about_ca_topic_score_codex":0.000017475524,"about_ca_topic_score_gemma":0.000004399668,"teacher_disagreement_score":0.16556479,"about_ca_system_score_codex":0.000008851232,"about_ca_system_score_gemma":0.00015275925,"threshold_uncertainty_score":0.71068066},"labels":[],"label_agreement":null},{"id":"W2790490581","doi":"10.1016/j.cep.2018.02.001","title":"A simplified strategy to reduce the desorbent consumption and equipment installed in a three-zone simulated moving bed process for the separation of glucose and fructose","year":2018,"lang":"en","type":"article","venue":"Chemical Engineering and Processing - Process Intensification","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Thailand Research Fund","keywords":"Raffinate; Simulated moving bed; Chromatography; Port (circuit theory); Chemistry; Pressure drop; Process engineering; Mechanics; Adsorption; Extraction (chemistry); Mechanical engineering; Engineering; Physics","score_opus":0.03182342369367404,"score_gpt":0.3241982490052353,"score_spread":0.2923748253115613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790490581","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95826966,0.0019242216,0.03882192,0.00026370876,0.000015818308,0.0006779157,0.000004673127,0.000016945009,0.0000051321135],"genre_scores_gemma":[0.9992618,0.0000631941,0.0003788843,0.000053413114,0.000039847135,0.0001599753,0.000025924013,0.000012681561,0.000004310764],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991608,0.000012132851,0.00027492872,0.00032037142,0.00009000417,0.00014174289],"domain_scores_gemma":[0.99928546,0.00004898897,0.00010080189,0.00015730344,0.00035494263,0.000052520878],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033471084,0.0001300294,0.00012839222,0.00003548579,0.00010114953,0.00004894764,0.00009516158,0.0001010888,6.5943095e-7],"category_scores_gemma":[0.0004923204,0.00009356766,0.000013888856,0.00013508706,0.00015657705,0.000017360753,0.000033909193,0.00008740821,1.0624739e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033955555,0.000034606335,0.0002921621,0.000431236,0.000014130728,4.1967493e-8,0.0010110233,0.001178603,0.96081364,0.00006773944,0.0000012293779,0.035816014],"study_design_scores_gemma":[0.00057942927,0.000137263,0.002700728,0.00012059536,0.00002368089,0.000006764427,0.00034003888,0.20225756,0.79331696,0.0002833516,0.00007954648,0.00015407654],"about_ca_topic_score_codex":0.0000066519924,"about_ca_topic_score_gemma":0.000007963049,"teacher_disagreement_score":0.20107895,"about_ca_system_score_codex":0.000014073598,"about_ca_system_score_gemma":0.000048428607,"threshold_uncertainty_score":0.38155782},"labels":[],"label_agreement":null},{"id":"W2791292871","doi":"10.1016/j.chroma.2018.03.029","title":"Feasibility study for high-resolution multi-component separation of protein mixture using a cation-exchange cuboid packed-bed device","year":2018,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cuboid; Chemistry; Chromatography; Packed bed; Volumetric flow rate; Resolution (logic); Elution; Isoelectric point; Theoretical plate; Analytical Chemistry (journal); Flow (mathematics); Column (typography); Mechanics; Geometry; Mathematics; Computer science","score_opus":0.03947279242311778,"score_gpt":0.3390518567256042,"score_spread":0.2995790643024864,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791292871","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.965582,0.0008664179,0.03190159,0.00007250803,0.000113365946,0.0014182522,0.000033612716,0.0000057198513,0.0000065107397],"genre_scores_gemma":[0.9872763,0.0000124002845,0.012396937,0.000024440344,0.00020505028,0.000042988064,0.000025186326,0.000011326123,0.0000053839867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986071,0.00020816705,0.00059866253,0.00022194847,0.00021857812,0.00014555966],"domain_scores_gemma":[0.99784505,0.000012444266,0.00073150254,0.0003325816,0.001004592,0.000073827716],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00088521675,0.0001350183,0.00023997405,0.0001253746,0.000116562034,0.000017823477,0.00017291582,0.00012130492,0.000008793871],"category_scores_gemma":[0.00015791543,0.00011781341,0.00019530195,0.00022559926,0.00012134945,0.000018732144,0.000027215401,0.000076814154,3.9159985e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006433555,0.0014267553,0.015103901,0.00010969336,0.00013252845,4.0147108e-7,0.0004575743,0.00000874768,0.98163563,0.00003692212,0.000060287624,0.00038419943],"study_design_scores_gemma":[0.0047671,0.0030799126,0.17545892,0.00009137858,0.00014262034,0.000024151135,0.0005079438,0.00077792665,0.81300807,0.0003763299,0.0014815602,0.00028406136],"about_ca_topic_score_codex":0.00004406392,"about_ca_topic_score_gemma":0.00012522232,"teacher_disagreement_score":0.16862753,"about_ca_system_score_codex":0.000033785014,"about_ca_system_score_gemma":0.00012811444,"threshold_uncertainty_score":0.48042917},"labels":[],"label_agreement":null},{"id":"W2793208501","doi":"10.1016/j.bpj.2011.11.2137","title":"A PagP Fusion Protein System for the Expression of Intrinsically Disordered Proteins in E. Coli","year":2012,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Bacterial outer membrane; Inclusion bodies; Biochemistry; Fusion protein; Chemistry; Biology; Biophysics; Escherichia coli; Recombinant DNA","score_opus":0.013315114029869235,"score_gpt":0.25290515461461405,"score_spread":0.2395900405847448,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2793208501","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98238313,0.00031587406,0.015742408,0.000313968,0.00009173996,0.0010883525,0.000013956464,0.0000053827594,0.00004518085],"genre_scores_gemma":[0.9983187,0.000018431787,0.0009954334,0.000016320348,0.00038660684,0.00021769406,0.00000642407,0.000009654945,0.000030754847],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908626,0.00012573207,0.00028876078,0.00013026285,0.00015606712,0.00021291687],"domain_scores_gemma":[0.99937975,0.000022694456,0.00016390315,0.0002390116,0.00010570092,0.00008895691],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043646066,0.000096200434,0.00013729488,0.000022502814,0.00010439395,0.00001586027,0.00019633537,0.00009333679,0.0000048387183],"category_scores_gemma":[0.0001756683,0.000059301983,0.00011672927,0.00008111709,0.0000752441,0.000007670243,0.00006737147,0.00013112265,0.0000018103661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003410482,0.00030715056,0.0005040694,0.000050708706,0.000007528467,1.8329955e-7,0.000059406117,0.0000028656295,0.99484676,0.0004879902,0.00003604423,0.003356216],"study_design_scores_gemma":[0.0007483248,0.00023441287,0.009885865,0.000064079344,0.000007219395,0.000005929208,0.0001964195,0.00007782608,0.9848623,0.00005237406,0.0037719663,0.000093270406],"about_ca_topic_score_codex":0.0000059547897,"about_ca_topic_score_gemma":0.000002496517,"teacher_disagreement_score":0.015935542,"about_ca_system_score_codex":0.00002338843,"about_ca_system_score_gemma":0.00005566383,"threshold_uncertainty_score":0.24182646},"labels":[],"label_agreement":null},{"id":"W2794284081","doi":"10.1016/j.ejpb.2018.02.033","title":"Effect of storage temperature on the stability of spray dried bacteriophage powders","year":2018,"lang":"en","type":"article","venue":"European Journal of Pharmaceutics and Biopharmaceutics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; Australian Research Council; Medical Research Council; National Institutes of Health; University of Sydney","keywords":"Spray drying; Bacteriophage; Chemistry; Pharmaceutical technology; Food science; Chemical engineering; Chromatography; Materials science; Biochemistry","score_opus":0.023013721129986783,"score_gpt":0.30345663328892875,"score_spread":0.28044291215894196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794284081","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99660325,0.001513677,0.000059340495,0.0003913121,0.00035122913,0.00028415737,0.00006193809,0.000004056735,0.00073105085],"genre_scores_gemma":[0.99832195,0.0008362636,0.00013026786,0.00035292222,0.00029708186,9.187202e-7,0.000005242199,0.000023860914,0.00003147051],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99734354,0.0013449035,0.00063256256,0.0002092119,0.00027505093,0.00019475224],"domain_scores_gemma":[0.9983498,0.000115183335,0.00059401157,0.0003637973,0.00041536955,0.00016184093],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0038024727,0.00021205087,0.00028399157,0.00006115123,0.0001053768,0.000024860026,0.0003874227,0.00006172552,0.00007781901],"category_scores_gemma":[0.00030357036,0.0001364338,0.00016706713,0.00015388257,0.0006554453,0.000009076603,0.000115619245,0.00035246563,0.00000273832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013898195,0.00012322652,0.0012826014,0.00012188087,0.000118687305,0.0000075906228,0.0002027962,0.0000028020645,0.9915773,0.00003513773,0.00014688911,0.0049912417],"study_design_scores_gemma":[0.0014520885,0.0021247533,0.0017393122,0.000035216435,0.000099683464,0.000023787663,0.00007541561,0.000041608044,0.9615069,0.000003542389,0.032776088,0.00012160562],"about_ca_topic_score_codex":3.421241e-7,"about_ca_topic_score_gemma":2.7973812e-7,"teacher_disagreement_score":0.0326292,"about_ca_system_score_codex":0.00001342149,"about_ca_system_score_gemma":0.000066179964,"threshold_uncertainty_score":0.5563609},"labels":[],"label_agreement":null},{"id":"W2795652893","doi":"10.1016/j.jchromb.2018.04.002","title":"Effects of process parameters on the efficiency of chromatographic separations using a cuboid packed-bed device","year":2018,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Science and Engineering Research Council; Natural Sciences and Engineering Research Council of Canada","keywords":"Cuboid; Packed bed; Chemistry; Chromatography; Volumetric flow rate; Elution; Volume (thermodynamics); Analytical Chemistry (journal); Flow (mathematics); Mechanics; Geometry; Mathematics; Thermodynamics","score_opus":0.014398116041006256,"score_gpt":0.28670139135304934,"score_spread":0.27230327531204307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2795652893","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970912,0.0010263385,0.0012684738,0.000072886265,0.00009534766,0.00029595863,0.0000062604463,0.0000039921906,0.00013953976],"genre_scores_gemma":[0.99901813,0.000072734656,0.0007529026,0.00008148456,0.00005409078,0.000007648594,0.000001640532,0.000010345697,0.0000010431763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986984,0.00017247521,0.0005340399,0.00015192624,0.00029173988,0.00015141646],"domain_scores_gemma":[0.99824846,0.00008379893,0.0007545411,0.00031934233,0.00052684074,0.00006704651],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044438426,0.00013420463,0.00024841094,0.00019279355,0.00009778584,0.000013327658,0.00032060113,0.00009594033,0.0000073707124],"category_scores_gemma":[0.00024279143,0.00009079505,0.00031413347,0.0006149572,0.0004927665,0.000009784262,0.0000210351,0.00010372579,5.448896e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001628828,0.0005430831,0.00590256,0.00019968463,0.00019538925,0.0000011382735,0.0003215911,0.000019205165,0.9921121,0.00030964927,0.000088791065,0.0001439191],"study_design_scores_gemma":[0.00048385726,0.0011973317,0.0070271585,0.00014308286,0.00006958734,0.000027768001,0.00013239104,0.00008430446,0.99009633,0.00040519694,0.00023371173,0.00009930128],"about_ca_topic_score_codex":0.0000053898416,"about_ca_topic_score_gemma":0.0000036069905,"teacher_disagreement_score":0.0020157974,"about_ca_system_score_codex":0.000005453931,"about_ca_system_score_gemma":0.00013972515,"threshold_uncertainty_score":0.37025148},"labels":[],"label_agreement":null},{"id":"W2806748964","doi":"10.1371/journal.pone.0197956","title":"Design of a glutamine substrate tag enabling protein labelling mediated by Bacillus subtilis transglutaminase","year":2018,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Bacillus subtilis; Tissue transglutaminase; Glutamine; Labelling; Biochemistry; Substrate (aquarium); Chemistry; Substrate specificity; Enzyme; Biology; Amino acid; Bacteria; Genetics","score_opus":0.03997340099806552,"score_gpt":0.2278479275170536,"score_spread":0.1878745265189881,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806748964","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9781749,0.0016145862,0.019028831,0.00013902043,0.000012024011,0.00076864,0.00010541291,0.00002846818,0.00012808938],"genre_scores_gemma":[0.9940885,0.00015492122,0.0049625966,0.0000464495,0.00007061541,0.00009423123,0.00017510344,0.000023068358,0.00038454222],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986481,0.00014220586,0.00034404715,0.00037901252,0.0002286845,0.00025796058],"domain_scores_gemma":[0.9990286,0.00002246789,0.00012904679,0.00041878383,0.00029719883,0.00010386505],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004746689,0.00015963611,0.00021766611,0.00003853043,0.00007386656,0.000013971029,0.00020689398,0.00016810879,0.00010185754],"category_scores_gemma":[0.0002812082,0.00015876019,0.00004408999,0.00017554793,0.00021460444,0.0000064239343,0.000024545641,0.00009273748,0.000017884702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023795458,0.00074258604,0.00014701062,0.000091601025,0.00010273013,8.6395676e-7,0.0001022491,0.000002803261,0.99800307,0.000009619926,0.000016309808,0.0005432308],"study_design_scores_gemma":[0.0006273356,0.0005295692,0.00009255969,0.000047323105,0.00003928657,5.8112136e-7,0.000028519993,0.0008448734,0.99711835,0.00003858721,0.000459343,0.00017365137],"about_ca_topic_score_codex":0.000021546055,"about_ca_topic_score_gemma":0.000013922701,"teacher_disagreement_score":0.015913544,"about_ca_system_score_codex":0.0000137998795,"about_ca_system_score_gemma":0.00008123416,"threshold_uncertainty_score":0.64740527},"labels":[],"label_agreement":null},{"id":"W2884563437","doi":"10.1016/j.pep.2018.07.007","title":"Systematic analysis of the expression, solubility and purification of a passenger protein in fusion with different tags","year":2018,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Protein tag; Fusion protein; Maltose-binding protein; Escherichia coli; Tandem affinity purification; Protein purification; Fusion; Biochemistry; Recombinant DNA; Target protein; Solubility; Biology; Affinity chromatography; Chemistry; Chromatography; Enzyme; Gene","score_opus":0.009460788237289849,"score_gpt":0.2375981098212309,"score_spread":0.22813732158394104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2884563437","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930704,0.0008544689,0.0033812122,0.00020837394,0.000016793365,0.002381473,0.000017717946,0.0000090209405,0.000060543203],"genre_scores_gemma":[0.99811053,0.0000518475,0.0010069857,0.000011677698,0.000017562468,0.00064804684,0.00003592505,0.000010593111,0.00010681687],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99793875,0.0005229814,0.00061927916,0.0004947313,0.0002811452,0.00014308844],"domain_scores_gemma":[0.9981705,0.000028315377,0.0005713394,0.00089380506,0.00027030418,0.000065753746],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072410196,0.00017522699,0.00034774665,0.0001370967,0.00011968909,0.000019299865,0.00020497119,0.00016907202,0.000017699822],"category_scores_gemma":[0.0003478548,0.00010538926,0.00006968512,0.00041015833,0.00032414502,0.000017264658,0.00010307997,0.00009862262,3.0317196e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022163946,0.00019864335,0.009770342,0.0011622647,0.000036369143,3.7934118e-8,0.00039703664,0.000002050429,0.98745686,0.00020958137,0.0000040398118,0.0005411376],"study_design_scores_gemma":[0.00037119808,0.00012513885,0.107893184,0.0009921239,0.00006654779,5.9597124e-7,0.00017988782,0.0003803302,0.8896487,0.00016637213,0.000057746303,0.000118184355],"about_ca_topic_score_codex":0.000027091126,"about_ca_topic_score_gemma":0.00006146173,"teacher_disagreement_score":0.09812284,"about_ca_system_score_codex":0.000015110967,"about_ca_system_score_gemma":0.000041096115,"threshold_uncertainty_score":0.42976496},"labels":[],"label_agreement":null},{"id":"W2891138113","doi":"10.3390/pr6090160","title":"Effect of the Length-to-Width Aspect Ratio of a Cuboid Packed-Bed Device on Efficiency of Chromatographic Separation","year":2018,"lang":"en","type":"article","venue":"Processes","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cuboid; Packed bed; Chromatography; Column (typography); Aspect ratio (aeronautics); Materials science; Elution; Chemistry; Analytical Chemistry (journal); Composite material; Geometry; Mathematics","score_opus":0.00778702956401177,"score_gpt":0.291104725036871,"score_spread":0.28331769547285923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891138113","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973119,0.0007019308,0.0006255587,0.0000710281,0.00003796351,0.00043281657,0.000013467741,0.0000061145824,0.0007992188],"genre_scores_gemma":[0.9997428,0.00004526144,0.00007519422,0.000037324513,0.000031258933,0.000036138383,0.000008318154,0.0000060519023,0.000017630695],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923146,0.000109927416,0.00022798355,0.00019261535,0.00015084023,0.00008720197],"domain_scores_gemma":[0.9990548,0.000045649715,0.00018622496,0.00035062828,0.0003385647,0.000024163235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003394717,0.000089706715,0.00014133945,0.000037049267,0.00004590408,0.0000043598166,0.00020427234,0.000060332193,0.000009628074],"category_scores_gemma":[0.000880139,0.00005974026,0.000056748446,0.00038270297,0.00017441697,0.000003486619,0.00003518011,0.000031919215,0.000002392939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026306883,0.000151574,0.008629824,0.0009131085,0.000023003427,2.4422254e-8,0.00023046006,0.000008315219,0.98815024,0.00013763923,0.000043614742,0.0014491328],"study_design_scores_gemma":[0.00022688761,0.0014039892,0.0038581167,0.000043301778,0.000014741735,6.090239e-7,0.000013583034,0.000020715212,0.99353266,0.000069207046,0.0007584461,0.000057737365],"about_ca_topic_score_codex":0.000009649869,"about_ca_topic_score_gemma":0.00003920829,"teacher_disagreement_score":0.0053824303,"about_ca_system_score_codex":0.0000039046536,"about_ca_system_score_gemma":0.00011742572,"threshold_uncertainty_score":0.2436137},"labels":[],"label_agreement":null},{"id":"W2892396837","doi":"10.5539/jmsr.v7n4p46","title":"Effect of Solvent on Catalysis of Protease Adsorbed on Biochar in Organic Media","year":2018,"lang":"en","type":"article","venue":"Journal of Materials Science Research","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Transesterification; Adsorption; Catalysis; Solvent; Organic solvent; Biochar; Materials science; Nuclear chemistry; Organic chemistry; Chemistry; Chemical engineering","score_opus":0.03188429302187979,"score_gpt":0.38211875293609565,"score_spread":0.35023445991421587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2892396837","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9993385,0.00007494677,0.000015535685,0.00016166674,0.00009742536,0.00024314524,0.000009571842,6.3104426e-7,0.000058569967],"genre_scores_gemma":[0.999771,0.00004864319,0.000055188826,0.000007251322,0.00009514641,0.00000674516,0.0000017199287,0.0000041922476,0.000010142407],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99802655,0.00052856805,0.0003943434,0.0001773421,0.0006689261,0.00020427475],"domain_scores_gemma":[0.9986422,0.000072430805,0.00022364984,0.00032630953,0.00064391276,0.0000914761],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.012414061,0.000062452265,0.00020110575,0.00031171553,0.0000488869,0.000018299304,0.0004834262,0.00005581184,0.00015778531],"category_scores_gemma":[0.0038984336,0.000042301945,0.000042716805,0.00044264755,0.00075666077,0.000007741367,0.000092977,0.00009056828,0.000010509415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010480811,0.00014559265,0.00016736085,0.000045992332,0.000004730712,0.0000013478086,0.000075894524,0.0000013916451,0.99741805,0.00003262334,0.000019527399,0.0010394165],"study_design_scores_gemma":[0.00038184258,0.003824706,0.0022341348,0.00006778142,0.0000024341496,0.0000030087517,0.000028618675,0.0000025021932,0.99330264,0.000051051084,0.000066718356,0.00003458188],"about_ca_topic_score_codex":0.000021702628,"about_ca_topic_score_gemma":0.0000068046256,"teacher_disagreement_score":0.008515628,"about_ca_system_score_codex":0.00004512196,"about_ca_system_score_gemma":0.00038709686,"threshold_uncertainty_score":0.46670708},"labels":[],"label_agreement":null},{"id":"W2895099705","doi":"10.1016/j.jpba.2018.09.056","title":"Assessment of the higher order structure of Humira®, Remicade®, Avastin®, Rituxan®, Herceptin®, and Enbrel® by 2D-NMR fingerprinting","year":2018,"lang":"en","type":"article","venue":"Journal of Pharmaceutical and Biomedical Analysis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Health Canada","funders":"","keywords":"Chemistry; Biosimilar; Heteronuclear molecule; Trastuzumab; Context (archaeology); Combinatorial chemistry; Stereochemistry; Chromatography; Nuclear magnetic resonance spectroscopy; Cancer; Internal medicine","score_opus":0.012407164927663113,"score_gpt":0.33361842086179183,"score_spread":0.3212112559341287,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2895099705","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934922,0.0012575737,0.0031143746,0.001863773,0.00007542981,0.00006668308,0.00004199554,0.0000017415209,0.000086236745],"genre_scores_gemma":[0.9974606,0.0002647863,0.0017690918,0.0002474375,0.00017396684,5.7862974e-7,0.000007755442,0.0000048910515,0.000070904185],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99854475,0.00016097487,0.00058188883,0.00020177201,0.00035963784,0.00015096257],"domain_scores_gemma":[0.9989107,0.00004590622,0.0003826602,0.00016950663,0.00031203538,0.00017915491],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005293268,0.00011711087,0.00032989302,0.00007292449,0.00006993894,0.000012452537,0.00020794378,0.00015689958,0.00033656994],"category_scores_gemma":[0.00019731438,0.000069116264,0.00017187986,0.0004378513,0.0009374865,0.000006198553,0.00015654808,0.00024932405,1.3887183e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055778437,0.00015000661,0.031141534,0.000051895804,0.0005185678,4.992194e-7,0.00003363285,9.011182e-7,0.9590638,0.000043495562,0.00029795698,0.008641882],"study_design_scores_gemma":[0.0026290407,0.00085574796,0.35196722,0.00009786064,0.0025988813,0.00005505182,0.000169937,0.0025753605,0.529452,0.00055605604,0.10863781,0.0004049891],"about_ca_topic_score_codex":0.000009734412,"about_ca_topic_score_gemma":0.0000032421128,"teacher_disagreement_score":0.4296118,"about_ca_system_score_codex":0.000009571494,"about_ca_system_score_gemma":0.00006626268,"threshold_uncertainty_score":0.36852047},"labels":[],"label_agreement":null},{"id":"W2903001438","doi":"10.20944/preprints201808.0284.v1","title":"Identity, structure and compositional analysis of adjuvanted vaccines","year":2018,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University; Sanofi (Canada)","funders":"York University; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Adjuvant; Antigen; Fourier transform infrared spectroscopy; Adsorption; Characterization (materials science); Vaccine efficacy; Materials science; Chemical engineering; Chemistry; Kinetics; Nanotechnology; Biology; Immune system; Immunology; Engineering; Physics","score_opus":0.04899624262407873,"score_gpt":0.35002850730181007,"score_spread":0.30103226467773136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2903001438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970631,0.00057723006,0.000986877,0.00011511326,0.00012462767,0.00028154862,0.00045439857,0.000015230046,0.000381878],"genre_scores_gemma":[0.99791765,0.00018029242,0.00037329612,0.000053913853,0.000098379336,0.000022145161,0.0012452201,0.000011514053,0.000097572316],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984667,0.00012175135,0.0003802368,0.00071241177,0.00019127836,0.00012765636],"domain_scores_gemma":[0.99830294,0.000011018951,0.00028421832,0.0009764843,0.0003512438,0.00007412277],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029217105,0.00019421028,0.00036092187,0.00014246644,0.00005461119,0.000013308154,0.00038098366,0.00033104274,0.0005988999],"category_scores_gemma":[0.00015406653,0.00019756769,0.0001997694,0.00017088074,0.00015830707,0.000004922263,0.0013621966,0.00018820813,0.000009187227],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000072040995,0.000060790888,0.6738138,0.00008828062,0.00096655154,3.3199788e-7,0.000050461294,0.00008669625,0.32460773,0.00015434044,0.000014654934,0.00008429196],"study_design_scores_gemma":[0.00015423153,0.000014995498,0.7777673,0.000014180982,0.0003360677,0.0000016273395,0.000009223347,0.00016009771,0.21963784,0.0013673479,0.0003863534,0.0001507397],"about_ca_topic_score_codex":0.00006460562,"about_ca_topic_score_gemma":0.00011094638,"teacher_disagreement_score":0.10496988,"about_ca_system_score_codex":0.000015295265,"about_ca_system_score_gemma":0.00007586604,"threshold_uncertainty_score":0.8056576},"labels":[],"label_agreement":null},{"id":"W2906321352","doi":"10.1080/19420862.2018.1544454","title":"Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics","year":2018,"lang":"en","type":"article","venue":"mAbs","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; Health Canada","funders":"Pacific Northwest National Laboratory; National Health and Medical Research Council; Biological and Environmental Research; Health Canada; Office of Science; National Institute of Standards and Technology; Stockholms Universitet; Knut och Alice Wallenbergs Stiftelse; Eidgenössische Technische Hochschule Zürich; Ministério da Ciência, Tecnologia, Inovações e Comunicações; Government of Canada; Ministry of Education, Culture, Sports, Science and Technology; Medical University of South Carolina; Medical Research Council; Biogen; U.S. Department of Energy; W. M. Keck Foundation; University of South Carolina","keywords":"Comparability; Biopharmaceutical; NIST; Consistency (knowledge bases); Computer science; Process analytical technology; Quality assurance; Biochemical engineering; Mathematics; Artificial intelligence; Engineering; Biotechnology; Biology; External quality assessment","score_opus":0.024400211407979353,"score_gpt":0.3409356002883238,"score_spread":0.31653538888034444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2906321352","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9301973,0.00086917594,0.06740399,0.00056521915,0.0001778915,0.0004025817,0.000085993815,0.000004965673,0.00029287284],"genre_scores_gemma":[0.9950006,0.000055147215,0.004502618,0.000108265456,0.0001271422,0.000010223353,0.00008409303,0.000005928254,0.0001059982],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995688,0.000025277173,0.0001379091,0.00011881148,0.00007632604,0.00007284487],"domain_scores_gemma":[0.999357,0.000013983565,0.000089066045,0.00025360569,0.00027505722,0.000011314411],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014371061,0.000055307362,0.00006677195,0.000010239128,0.00004646237,0.0000052286127,0.00010850845,0.00007207963,0.000052513424],"category_scores_gemma":[0.000016471025,0.000037425256,0.000040574498,0.000049420076,0.00010554966,0.000001607603,0.000025939797,0.000033606786,2.6362758e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055422297,0.00003640905,0.0031869144,0.000022820379,0.000046027,1.1883285e-8,0.00002613666,0.000023131754,0.99028945,0.0020139595,0.00003786946,0.0042618215],"study_design_scores_gemma":[0.0006963102,0.00045301003,0.15751751,0.000009268583,0.000051066832,9.5159356e-7,0.00009632969,0.001716514,0.6957097,0.0014343908,0.1421817,0.0001332585],"about_ca_topic_score_codex":0.0000060924417,"about_ca_topic_score_gemma":0.0000059353138,"teacher_disagreement_score":0.29457977,"about_ca_system_score_codex":0.000004990628,"about_ca_system_score_gemma":0.000049628743,"threshold_uncertainty_score":0.15261576},"labels":[],"label_agreement":null},{"id":"W2910073867","doi":"10.1136/annrheumdis-2018-eular.3433","title":"SAT0074 Identification of a protein panel useful for the prediction of response to methotrexate in rheumatoid arthritis patients","year":2018,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Arthritis Network; Canadian Institutes of Health Research; National Natural Science Foundation of China; Ontario Ministry of Health and Long-Term Care; Celgene; Sanofi; Amgen; Pfizer; Natural Science Foundation of Guangdong Province; Eli Lilly and Company","keywords":"Medicine; Rheumatoid arthritis; Methotrexate; Identification (biology); Arthritis; Immunology; Internal medicine","score_opus":0.040624096501430305,"score_gpt":0.3001951283375929,"score_spread":0.2595710318361626,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2910073867","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954205,0.00078212377,0.0013191623,0.00057401904,0.00005749646,0.0013450742,0.0004914643,0.0000034942125,0.000006643617],"genre_scores_gemma":[0.9992767,0.00023674892,0.00012041365,0.000040174444,0.000007266677,0.00025086463,0.000024658008,0.000007891154,0.000035287492],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987106,0.00028249974,0.0005602988,0.0001663501,0.00017402225,0.00010627284],"domain_scores_gemma":[0.9984584,0.00010461213,0.00038128713,0.00060627237,0.0004130364,0.000036397294],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00084741553,0.00007977682,0.00015587661,0.000043906093,0.00005131905,0.0000068433446,0.00028593093,0.000042478427,0.000007819244],"category_scores_gemma":[0.0036285738,0.000053922813,0.000119725366,0.0001539574,0.00018607615,0.0000072418356,0.000067747664,0.000021174768,0.000001064833],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011865475,0.0026185869,0.07420975,0.0009696666,0.0003983765,6.326608e-8,0.0026230582,0.00016899427,0.7247545,0.0008037681,0.0017123116,0.17987546],"study_design_scores_gemma":[0.0004674292,0.0002769631,0.5282466,0.00022487075,0.000008147336,1.326383e-7,0.00010887945,0.00015694331,0.4689926,0.0008253255,0.00064207026,0.000050089027],"about_ca_topic_score_codex":0.000039162012,"about_ca_topic_score_gemma":0.000015655498,"teacher_disagreement_score":0.4540368,"about_ca_system_score_codex":0.0000060881107,"about_ca_system_score_gemma":0.00007299402,"threshold_uncertainty_score":0.43440038},"labels":[],"label_agreement":null},{"id":"W2913572526","doi":"10.1016/j.pep.2019.01.007","title":"Review of lactose-driven auto-induction expression of isotope-labelled proteins","year":2019,"lang":"en","type":"review","venue":"Protein Expression and Purification","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trent University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Lactose; lac operon; Protein expression; Recombinant DNA; Isotope; Biochemistry; Chemistry; Labelling; Stable isotope ratio; Yield (engineering); Computational biology; Stable isotope labeling by amino acids in cell culture; Biology; Proteomics; Materials science; Gene; Physics","score_opus":0.042737672084500286,"score_gpt":0.3223663042169858,"score_spread":0.2796286321324855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2913572526","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015856783,0.9915776,0.0011432231,0.000061005823,0.000093096314,0.0064922185,0.000110439716,0.000024922847,0.00033887528],"genre_scores_gemma":[0.0011460701,0.9929962,0.0028259465,0.000027008624,0.00009122126,0.001395917,0.00083245494,0.00005394703,0.0006312382],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9965874,0.0007288133,0.0012954344,0.0008345349,0.00033542566,0.0002183767],"domain_scores_gemma":[0.9963836,0.00002917475,0.0017820065,0.0013534282,0.00033892752,0.00011284881],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00075936096,0.00043543702,0.0012524805,0.00014546038,0.00008550976,0.00001558459,0.0004314823,0.0006555028,0.00009911401],"category_scores_gemma":[0.0004363289,0.00034182938,0.0003552324,0.00025086297,0.00015031116,0.0000206448,0.00018726094,0.00030071026,0.0000147755945],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004923877,0.00021188639,0.00000368658,0.1330795,0.000029927432,1.1343527e-7,0.00002745325,2.1265821e-7,0.5196608,0.000089233654,0.00042161622,0.34642634],"study_design_scores_gemma":[0.0002680063,0.00014835627,0.0000059912913,0.064550914,0.00011641348,0.0000044380895,0.0000091637,0.0000043820037,0.20281126,0.000027814734,0.7317615,0.00029173098],"about_ca_topic_score_codex":0.000006557063,"about_ca_topic_score_gemma":4.3517107e-7,"teacher_disagreement_score":0.73133993,"about_ca_system_score_codex":0.00002776426,"about_ca_system_score_gemma":0.00030856635,"threshold_uncertainty_score":0.9999034},"labels":[],"label_agreement":null},{"id":"W2921705183","doi":"10.1016/j.memsci.2019.03.026","title":"Enhancing the efficiency of disc membrane chromatography modules by using a flow directing layer","year":2019,"lang":"en","type":"article","venue":"Journal of Membrane Science","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Shastri Indo-Canadian Institute","keywords":"Membrane; Chemistry; Header; Chromatography; Inlet; Flow (mathematics); Path length; Elution; Analytical Chemistry (journal); Mechanics; Optics; Physics; Mathematics; Geology","score_opus":0.009211706336336485,"score_gpt":0.2574659030292927,"score_spread":0.2482541966929562,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921705183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945219,0.0012161267,0.0034494642,0.00012890164,0.00022915642,0.00013195483,0.000004404426,0.0000026922162,0.0003153835],"genre_scores_gemma":[0.9979511,0.00008121763,0.0018361871,0.00004373795,0.00004942943,8.970254e-7,6.0567436e-7,0.0000058591213,0.000030981955],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99863094,0.000079908554,0.00041852763,0.00020936076,0.00045637466,0.00020491051],"domain_scores_gemma":[0.99887687,0.00003699482,0.00041074664,0.00033461183,0.0002672041,0.000073571355],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022496753,0.000095028954,0.00017626114,0.00008284367,0.00015706522,0.000037159556,0.00055944076,0.00004481013,0.000022962045],"category_scores_gemma":[0.00035395505,0.000060699665,0.00012944474,0.0004465671,0.0003477588,0.000026202764,0.00007433802,0.000120558136,0.0000011293638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023913808,0.00004964895,0.0008183044,0.000029204384,0.000009331687,2.7828534e-7,0.0001385098,0.00052638375,0.9975752,0.000013369714,0.0000046927285,0.000811163],"study_design_scores_gemma":[0.00023069921,0.00010108349,0.0007038365,0.00004311475,0.000009877972,0.000041374064,0.00023656256,0.0021348475,0.995969,0.000013508287,0.00043826483,0.00007780599],"about_ca_topic_score_codex":0.000013171649,"about_ca_topic_score_gemma":0.0000038133055,"teacher_disagreement_score":0.0034291681,"about_ca_system_score_codex":0.000015556483,"about_ca_system_score_gemma":0.00019407114,"threshold_uncertainty_score":0.24752606},"labels":[],"label_agreement":null},{"id":"W2924129736","doi":"10.3389/fmicb.2019.00488","title":"Atmospheric Spray Freeze Drying of Sugar Solution With Phage D29","year":2019,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Mannitol; Freeze-drying; Trehalose; Sublimation (psychology); Sugar; Spray drying; Chemistry; Chromatography; Atmospheric pressure; Materials science; Food science; Biochemistry","score_opus":0.0031374980780284755,"score_gpt":0.19185194858442542,"score_spread":0.18871445050639693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2924129736","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9744992,0.002339403,0.021690005,0.0000775503,0.00032774676,0.00032013055,0.000021601008,0.000007842792,0.0007164802],"genre_scores_gemma":[0.976811,0.00006537102,0.022386976,0.00009083611,0.000023606275,0.000013690109,0.00012788437,0.000011005357,0.00046961624],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913883,0.00010347486,0.00020374332,0.00032012453,0.000026506545,0.00020731475],"domain_scores_gemma":[0.99946487,0.0000054429966,0.000105446794,0.0003508528,0.000048352176,0.000025006468],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020425566,0.000109630775,0.00019772683,0.00001639708,0.000020610425,0.0000032523405,0.00017527165,0.00017912038,0.000045626173],"category_scores_gemma":[0.000027008591,0.00009698246,0.000045532488,0.00010173736,0.0001502388,0.000003502377,0.000048361355,0.00009034892,0.000009478094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001545781,0.000047386362,0.14310873,0.000021508571,0.000024261797,4.987177e-7,0.000034623252,0.000024580902,0.85454047,0.000025333771,0.0008179428,0.0012000606],"study_design_scores_gemma":[0.001786493,0.00058299507,0.018758664,0.000024144443,0.00001364419,0.00001905592,0.00022792185,0.000104264676,0.90037656,0.000085411535,0.077709116,0.00031172257],"about_ca_topic_score_codex":0.000025886739,"about_ca_topic_score_gemma":0.00003660823,"teacher_disagreement_score":0.12435007,"about_ca_system_score_codex":0.000027460377,"about_ca_system_score_gemma":0.000060119677,"threshold_uncertainty_score":0.395483},"labels":[],"label_agreement":null},{"id":"W2930265077","doi":"10.1016/j.resmic.2019.03.004","title":"Effect of the optimized selective enrichment medium on the expression of the p60 protein used as Listeria monocytogenes antigen in specific sandwich ELISA","year":2019,"lang":"en","type":"article","venue":"Research in Microbiology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"FPInnovations; Institut National de la Recherche Scientifique","funders":"Ministère de l'Économie, de l’Innovation et des Exportations du Québec; Armand-Frappier Foundation","keywords":"Listeria monocytogenes; Biology; Monoclonal antibody; Brain heart infusion; Microbiology; Incubation; Molecular biology; Bacteria; Antibody; Biochemistry; Immunology","score_opus":0.030185283237155983,"score_gpt":0.33811531597216005,"score_spread":0.3079300327350041,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2930265077","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954444,0.0006064931,0.000004553021,0.000753562,0.00008610809,0.0027445264,0.000021206268,0.000001799897,0.00033731243],"genre_scores_gemma":[0.99939466,0.00012785815,0.000027936596,0.000028322182,0.000022367933,0.0002065144,0.000013009504,0.000009103934,0.00017025905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99512595,0.0037570805,0.000302513,0.0003665475,0.00015262983,0.00029525973],"domain_scores_gemma":[0.99862134,0.0002774501,0.00012188439,0.0008484217,0.00010901056,0.000021908032],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003146542,0.00012550937,0.00023138883,0.00006617524,0.00006422586,0.000007913095,0.000722734,0.00019676171,0.00005882111],"category_scores_gemma":[0.00039206247,0.000059114886,0.000094627794,0.00031638128,0.00037318544,0.0000025310114,0.00039280337,0.00031967656,0.000008371894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009166747,0.00009848988,0.01746423,0.000038104332,0.000013185689,2.2904707e-7,0.00013557178,0.00003722629,0.98099065,0.00005317017,0.000100617515,0.00015183323],"study_design_scores_gemma":[0.00096870714,0.00047839776,0.01360477,0.00007924676,0.0000011938117,0.0000015321721,0.00006163075,0.000005351673,0.9826454,0.00007534907,0.0020190766,0.00005934703],"about_ca_topic_score_codex":0.00007604717,"about_ca_topic_score_gemma":0.000046109977,"teacher_disagreement_score":0.0039501893,"about_ca_system_score_codex":0.00006289874,"about_ca_system_score_gemma":0.00017266367,"threshold_uncertainty_score":0.2410635},"labels":[],"label_agreement":null},{"id":"W2935481530","doi":"10.1007/s10989-019-09840-4","title":"Progress and Challenges in PEGylated Proteins Downstream Processing: A Review of the Last 8 Years","year":2019,"lang":"en","type":"review","venue":"International Journal of Peptide Research and Therapeutics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Instituto Tecnológico y de Estudios Superiores de Monterrey; Consejo Nacional de Ciencia y Tecnología; World Anti-Doping Agency","keywords":"PEGylation; Context (archaeology); Chemistry; PEG ratio; Chromatography; Downstream processing; Polyethylene glycol; Organic chemistry; Biology; Business","score_opus":0.19137377300371855,"score_gpt":0.43871929195868287,"score_spread":0.24734551895496432,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2935481530","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004966752,0.9979386,0.000002696355,0.00074351416,0.000048787013,0.0005942495,0.000017350976,8.409833e-7,0.00015731959],"genre_scores_gemma":[0.003658306,0.9960388,0.00008503636,0.0000240957,0.0000878475,0.00002371525,0.000008848264,0.00001259333,0.000060766157],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99833477,0.0003385574,0.0005106389,0.00018092748,0.0005003354,0.00013478089],"domain_scores_gemma":[0.9985242,0.000042632775,0.00043802283,0.00020283184,0.0007452178,0.000047128095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013367226,0.00012161695,0.00040440235,0.0001368123,0.00002013463,0.000032145024,0.0004897364,0.00013977707,0.0000046364594],"category_scores_gemma":[0.00014737688,0.00007652679,0.0001229033,0.00012614427,0.00027751565,0.000007938657,0.00017093815,0.0004282026,6.802361e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031692347,0.000116582145,0.00013637406,0.013411023,0.00014623677,0.0000037358602,0.00004257923,3.2583117e-8,0.000037885573,0.0001001744,0.000011677768,0.98596203],"study_design_scores_gemma":[0.0002618373,0.0002511122,0.00053709233,0.03135853,0.000040294926,0.00011979907,0.00003769563,0.0000013234236,0.00005478961,0.00016495374,0.9670899,0.00008269204],"about_ca_topic_score_codex":0.0000018221116,"about_ca_topic_score_gemma":0.000008738899,"teacher_disagreement_score":0.9858793,"about_ca_system_score_codex":0.000033318152,"about_ca_system_score_gemma":0.0005386482,"threshold_uncertainty_score":0.3120672},"labels":[],"label_agreement":null},{"id":"W2946455940","doi":"10.18433/jpps30427","title":"Evaluation of the Physicochemical and Biological Stability of Cetuximab under Various Stress Condition","year":2019,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"CinnaGen; University of Tabriz; Tabriz University of Medical Sciences","keywords":"Cetuximab; Monoclonal antibody; Chemistry; Epidermal growth factor receptor; Epidermal growth factor; Cell; Antibody; Receptor; Biochemistry; Medicine; Immunology","score_opus":0.09898651596601186,"score_gpt":0.40755379348754006,"score_spread":0.3085672775215282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2946455940","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970051,0.0016603034,0.00013886366,0.0004957889,0.00013927674,0.00024832814,0.000019753732,0.000001360898,0.00029122818],"genre_scores_gemma":[0.9995707,0.00016926449,0.000098846365,0.000102842656,0.000049922164,0.0000026025139,0.0000018594029,0.0000021775888,0.0000017342514],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998206,0.00045782086,0.00038527456,0.00018106963,0.00064499304,0.00012483164],"domain_scores_gemma":[0.998907,0.000071407514,0.00031739956,0.00012760582,0.000502276,0.00007427313],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0028085872,0.00008151296,0.00016281795,0.000022204493,0.00004908575,0.000010815892,0.00028442597,0.000043897715,0.00019036609],"category_scores_gemma":[0.0002918354,0.000049058286,0.00010522647,0.00014716035,0.000757682,0.000018200195,0.00009050434,0.0001412821,5.8141984e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010753985,0.0002660059,0.04934093,0.000024219147,0.000028307997,5.2549826e-8,0.000036794096,0.00007920557,0.94195664,0.00022091571,0.000009915982,0.007929488],"study_design_scores_gemma":[0.0013376328,0.00016636007,0.025638023,0.000013141377,0.0000754855,0.000009347574,0.000115185845,0.0023926406,0.96839696,0.00097341806,0.00081931654,0.000062472885],"about_ca_topic_score_codex":0.000004877737,"about_ca_topic_score_gemma":9.324173e-7,"teacher_disagreement_score":0.02644035,"about_ca_system_score_codex":0.000023849669,"about_ca_system_score_gemma":0.00025438628,"threshold_uncertainty_score":0.2791711},"labels":[],"label_agreement":null},{"id":"W2952362945","doi":"10.1002/chin.200736269","title":"Structural Modelling of Metal Ion Binding to Human Haemopexin","year":2007,"lang":"en","type":"article","venue":"ChemInform","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Metal ions in aqueous solution; Metal; Computational biology; Combinatorial chemistry; Nanotechnology; Organic chemistry","score_opus":0.036293691528394165,"score_gpt":0.28653430877124947,"score_spread":0.2502406172428553,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952362945","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9647699,0.00007479729,0.0012534985,0.000018456945,0.000042946107,0.00013448694,0.00000788318,0.000007979412,0.033690043],"genre_scores_gemma":[0.9977976,0.0000025694205,0.00077412056,0.000034381286,0.00006258139,0.0000040322984,0.00008589795,0.00000605366,0.001232761],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99940985,4.318184e-7,0.00021452027,0.00013773034,0.00009009881,0.00014737375],"domain_scores_gemma":[0.9995766,0.000003535748,0.000061573366,0.00022605245,0.00006307213,0.0000691203],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026125996,0.00007516378,0.00008547717,0.00003268975,0.000048839032,0.000006208009,0.00012577558,0.00007714705,0.000026964179],"category_scores_gemma":[0.000033262124,0.000070452996,0.000054117558,0.0000704023,0.0000342542,0.0000039209935,0.00005275521,0.00004371401,0.0000043205337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037313483,0.000008692466,0.00019944253,0.000020037909,0.000011684209,2.1152054e-7,0.00013887067,0.00003649739,0.97842115,0.00034676582,0.0000777981,0.020701526],"study_design_scores_gemma":[0.0001283417,0.000042798896,0.00039042308,0.000004330798,0.0000035496325,0.0000019076879,0.00008651768,0.000051015984,0.9938852,0.00005812508,0.005259825,0.00008794759],"about_ca_topic_score_codex":0.000011038106,"about_ca_topic_score_gemma":0.000007577926,"teacher_disagreement_score":0.033027694,"about_ca_system_score_codex":0.000016309099,"about_ca_system_score_gemma":0.000016971999,"threshold_uncertainty_score":0.28729898},"labels":[],"label_agreement":null},{"id":"W2954626530","doi":"10.1016/j.jpba.2019.06.039","title":"Part 1: Physicochemical characterization of bevacizumab in undiluted 25 mg/mL drug product solutions: Comparison of originator with a biosimilar candidate","year":2019,"lang":"en","type":"article","venue":"Journal of Pharmaceutical and Biomedical Analysis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Apotex (Canada)","funders":"","keywords":"Chemistry; Fluorescence spectroscopy; Dynamic light scattering; Chromatography; Particle size; Bevacizumab; Nanoparticle; Fluorescence; Analytical Chemistry (journal); Nanotechnology","score_opus":0.01400634449226717,"score_gpt":0.3041432318958164,"score_spread":0.2901368874035492,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2954626530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99691087,0.00074887613,0.0008687164,0.0012294234,0.000041689644,0.00013393976,0.000053171967,0.000001974426,0.000011362591],"genre_scores_gemma":[0.9992092,0.00033113535,0.00020376897,0.000050539507,0.000064893764,0.0000031725212,0.000109832785,0.000004584624,0.00002287007],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852896,0.00011970838,0.00064526673,0.00021618379,0.00032638587,0.00016351891],"domain_scores_gemma":[0.99904996,0.000022143413,0.0003850311,0.00016241525,0.00022561042,0.000154865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004921531,0.00011352025,0.0004705746,0.0001873456,0.000021743697,0.000007509482,0.0001399464,0.00007477285,0.00007638668],"category_scores_gemma":[0.00006987926,0.00007765292,0.00013842333,0.00070775923,0.00028662034,0.000012988059,0.000047416037,0.0001681965,6.507416e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005462351,0.0007889785,0.05640667,0.000110066,0.00052674976,0.0000013629755,0.00006467502,0.0000057256493,0.9388767,0.000045502515,0.000038519825,0.0025888102],"study_design_scores_gemma":[0.003053672,0.00057247834,0.051328063,0.00010355818,0.001045179,0.000013011511,0.00012564598,0.0049881954,0.9164217,0.000052642623,0.022045456,0.00025041017],"about_ca_topic_score_codex":0.000010394767,"about_ca_topic_score_gemma":0.000007001988,"teacher_disagreement_score":0.022455018,"about_ca_system_score_codex":0.000019959762,"about_ca_system_score_gemma":0.00011368794,"threshold_uncertainty_score":0.31665942},"labels":[],"label_agreement":null},{"id":"W2958805208","doi":"10.1371/journal.pone.0219156","title":"Exploring the analytical power of the QTOF MS platform to assess monoclonal antibodies quality attributes","year":2019,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"","keywords":"Biosimilar; Monoclonal antibody; Biopharmaceutical; Pace; Computer science; Quality (philosophy); Quality by Design; Computational biology; New product development; Product (mathematics); Critical quality attributes; Antibody; Data mining; Biotechnology; Medicine; Business; Immunology; Marketing; Biology; Mathematics; Physics","score_opus":0.24091401542322755,"score_gpt":0.31661499951044675,"score_spread":0.0757009840872192,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2958805208","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971862,0.000095159136,0.00010248946,0.0011996481,0.000043466793,0.00032857186,0.000052928906,0.000006446771,0.0009851085],"genre_scores_gemma":[0.99913055,0.000025138403,0.0002752341,0.00015526138,0.00003595179,0.000031075255,0.000015087486,0.0000061764217,0.00032555],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913883,0.000063034444,0.00021166257,0.00020249472,0.00024158513,0.00014239502],"domain_scores_gemma":[0.9990789,0.000047740377,0.00006482149,0.000628635,0.0001379067,0.000041977695],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004227232,0.00008232783,0.00014769522,0.000011682856,0.0000590281,0.000014404423,0.0002930714,0.00004498635,0.000048879436],"category_scores_gemma":[0.0003564719,0.000049054554,0.000082593295,0.000092051014,0.000077340206,0.0000063895277,0.00017346695,0.0000890503,0.00001713664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009472337,0.00047100795,0.2284183,0.00005411556,0.00016538988,9.208688e-8,0.00015833572,0.000010225849,0.7673411,0.003052126,0.000054741682,0.00017985074],"study_design_scores_gemma":[0.00011069058,0.00006653514,0.42679754,0.000017193164,0.000015112389,2.844026e-7,0.00012509983,0.000027001282,0.5716964,0.0000847822,0.0009840109,0.00007534359],"about_ca_topic_score_codex":0.00002027881,"about_ca_topic_score_gemma":0.000013534487,"teacher_disagreement_score":0.19837925,"about_ca_system_score_codex":0.000011584518,"about_ca_system_score_gemma":0.00004009035,"threshold_uncertainty_score":0.20003866},"labels":[],"label_agreement":null},{"id":"W2969000569","doi":"10.1016/j.ijpharm.2019.118615","title":"Stabilization of HSV-2 viral vaccine candidate by spray drying","year":2019,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University Medical Centre; University of British Columbia; Sanofi (Canada); McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Excipient; Trehalose; Spray drying; Sucrose; Chromatography; Dosage form; Chemistry; Materials science; Food science; Biochemistry","score_opus":0.010291821038704973,"score_gpt":0.32230433736803316,"score_spread":0.3120125163293282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969000569","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99393857,0.001068569,0.0033268249,0.00049052836,0.00065437704,0.00010094698,0.00005316813,0.000002419939,0.00036460956],"genre_scores_gemma":[0.9985728,0.00045277044,0.00036953378,0.00021548833,0.00014414934,9.867156e-7,0.000051653955,0.000008500292,0.0001840727],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908143,0.00005485642,0.00039843988,0.00010123084,0.0002811323,0.000082888015],"domain_scores_gemma":[0.9988548,0.000014525612,0.00037871656,0.000114916,0.00058352813,0.000053471587],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003439764,0.00007454902,0.00011014353,0.000054772114,0.000012559527,0.000014738289,0.00029384153,0.000052227977,0.0001613356],"category_scores_gemma":[0.000096069394,0.00006842046,0.00007811993,0.000041104013,0.000021078262,0.000014305571,0.000048974176,0.00010062154,0.0000046671958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002679156,0.000098734214,0.026692308,0.000011974691,0.0001028958,0.0000010346599,0.000043952572,0.00015043981,0.9687725,0.00010092455,0.0003205458,0.0034368122],"study_design_scores_gemma":[0.001125843,0.00009587758,0.0010237995,0.000012886944,0.000014856876,0.000017303628,0.000034348937,0.00022829472,0.9026352,0.00007113327,0.09467314,0.00006729711],"about_ca_topic_score_codex":0.000003729507,"about_ca_topic_score_gemma":0.000001930339,"teacher_disagreement_score":0.094352596,"about_ca_system_score_codex":0.00003399519,"about_ca_system_score_gemma":0.00008564457,"threshold_uncertainty_score":0.2790105},"labels":[],"label_agreement":null},{"id":"W296922409","doi":"10.1533/9781855738379.2.323","title":"The extraction and purification of proteins: an introduction","year":2004,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Extraction (chemistry); Protein purification; Computational biology; Chromatography; Biology; Chemistry","score_opus":0.011064701298014257,"score_gpt":0.24827696493597087,"score_spread":0.2372122636379566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W296922409","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0069378414,0.012062881,0.0004605321,0.0018661985,0.0006005304,0.0037777459,0.000063286614,0.000054173695,0.9741768],"genre_scores_gemma":[0.13320379,0.0014099156,0.0011099911,0.00004916345,0.0010692955,0.00020223144,0.00026223317,0.000059301143,0.86263406],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990444,0.00004147305,0.00030210975,0.0003814052,0.00013390266,0.00009670406],"domain_scores_gemma":[0.998831,0.0000056106437,0.00028165773,0.0006710223,0.00016240733,0.00004834598],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037611174,0.00015999292,0.00013226665,0.000028673428,0.00013318287,0.000025359688,0.00012770882,0.000261278,0.000015848549],"category_scores_gemma":[0.00005157545,0.00012830946,0.00006226041,0.0000062084487,0.0002352282,0.000004194958,0.000031672025,0.00015713323,0.0000029845346],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060289887,0.00001496292,0.000002428278,0.00004195083,0.000027279975,1.2663304e-7,0.000032449625,7.666348e-7,0.066477925,0.02016902,0.000011361807,0.91316146],"study_design_scores_gemma":[0.00013998566,0.00016455716,0.00016460681,0.0000177788,0.000025533298,0.000008686434,0.000011327799,0.0000016779835,0.041153688,0.012101022,0.9460654,0.0001457196],"about_ca_topic_score_codex":6.8311783e-7,"about_ca_topic_score_gemma":0.000022222097,"teacher_disagreement_score":0.94605404,"about_ca_system_score_codex":0.000026855621,"about_ca_system_score_gemma":0.0001057963,"threshold_uncertainty_score":0.52323085},"labels":[],"label_agreement":null},{"id":"W2972323172","doi":"10.5731/pdajpst.2018.009415","title":"Control Strategy Approach for a Well-Characterized Vaccine Drug Product","year":2019,"lang":"en","type":"article","venue":"PDA Journal of Pharmaceutical Science and Technology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Quality by Design; Computer science; Quality (philosophy); Risk analysis (engineering); New product development; Product (mathematics); Process management; Process (computing); Biochemical engineering; Business; Engineering; Mathematics","score_opus":0.013053762510662162,"score_gpt":0.3026611585281151,"score_spread":0.28960739601745294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972323172","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.985163,0.0016702734,0.0076419646,0.004495187,0.00012249862,0.00059269357,0.0000063957636,0.000010152095,0.00029785626],"genre_scores_gemma":[0.99727935,0.00013069062,0.0021789765,0.00025114612,0.000071024544,0.000015602129,0.0000018471155,0.000004801129,0.00006659531],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990127,0.000028656905,0.00026182007,0.00027968668,0.00016895263,0.0002481591],"domain_scores_gemma":[0.9990458,0.000014771237,0.00014391892,0.00018803468,0.0004930817,0.000114388],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013307738,0.000090717214,0.00018391221,0.000119221586,0.00007902209,0.000027189748,0.00033722012,0.000068592286,0.000026083142],"category_scores_gemma":[0.00031467556,0.000067405905,0.00004125864,0.0002681821,0.00031362424,0.00001684901,0.00005854279,0.00016810119,0.000002300978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026646335,0.000099735575,0.002024013,0.000022540798,0.000018524923,7.0555114e-7,0.000004807578,0.000002335928,0.9692729,0.0013133107,0.0000719166,0.026902745],"study_design_scores_gemma":[0.0039016167,0.0005986391,0.0014353467,0.0000067086476,0.000038425133,0.00023017131,0.00008670836,0.0013273604,0.8566822,0.00095202064,0.13456139,0.00017942833],"about_ca_topic_score_codex":5.29754e-7,"about_ca_topic_score_gemma":1.962563e-7,"teacher_disagreement_score":0.13448948,"about_ca_system_score_codex":0.000014830282,"about_ca_system_score_gemma":0.00019420184,"threshold_uncertainty_score":0.2748733},"labels":[],"label_agreement":null},{"id":"W2980222461","doi":"10.1042/bio04102014","title":"Measuring molecular interactions in solution using multi-wavelength analytical ultracentrifugation: combining spectral analysis with hydrodynamics","year":2019,"lang":"en","type":"article","venue":"The Biochemist","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"National Institute of General Medical Sciences","keywords":"Analytical Ultracentrifugation; Ultracentrifuge; Nanotechnology; Colloid; Wavelength; Computer science; Chemistry; Materials science; Physics; Chromatography; Optics","score_opus":0.028055729133711023,"score_gpt":0.2713542033975984,"score_spread":0.2432984742638874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980222461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97981185,0.00015047178,0.019138819,0.00016854412,0.000032021024,0.00022408909,0.000007573128,0.000012191092,0.0004544256],"genre_scores_gemma":[0.99829125,0.000010477793,0.0013632493,0.000031163247,0.000027678501,0.000009790678,0.00010920697,0.000011731414,0.00014547475],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989896,0.000074077725,0.00022299927,0.00034783818,0.00015242619,0.00021306788],"domain_scores_gemma":[0.9992648,0.000013674201,0.00009766908,0.00049066934,0.00007973611,0.000053496893],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003065868,0.00013533546,0.0001513339,0.00006537063,0.000081329985,0.000033531236,0.00017234356,0.000061926294,0.000016166994],"category_scores_gemma":[0.00006321136,0.00010947835,0.00010552071,0.0004292672,0.000090377944,0.0000070975602,0.00004037472,0.00016028727,0.000004021099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000112959715,0.00015123203,0.045295093,0.000016261747,0.0002377968,0.0000016917289,0.0000951486,0.006387596,0.9474359,0.00013290564,0.0000016559231,0.00013176657],"study_design_scores_gemma":[0.0010136289,0.0000477047,0.025430435,0.000026372885,0.00021975026,0.000018393384,0.00032035718,0.45589614,0.5164901,0.000014428622,0.00019565622,0.0003270522],"about_ca_topic_score_codex":0.00008170579,"about_ca_topic_score_gemma":0.0001745537,"teacher_disagreement_score":0.44950855,"about_ca_system_score_codex":0.00009407032,"about_ca_system_score_gemma":0.000067470006,"threshold_uncertainty_score":0.44643974},"labels":[],"label_agreement":null},{"id":"W2982366253","doi":"10.3390/membranes9110138","title":"Performance Comparison of a Laterally-Fed Membrane Chromatography (LFMC) Device with a Commercial Resin Packed Column","year":2019,"lang":"en","type":"article","venue":"Membranes","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chromatography; Chemistry; Membrane; Lysozyme; Packed bed; Analytical Chemistry (journal); Biochemistry","score_opus":0.011820377654075216,"score_gpt":0.2525183427067344,"score_spread":0.2406979650526592,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982366253","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966706,0.00048486335,0.000019592153,0.00014539037,0.000056766767,0.00048332752,0.000016321628,0.000022290202,0.00210085],"genre_scores_gemma":[0.99895775,0.00006445262,0.00040276707,0.000116916846,0.00003356643,0.00003431879,0.00010379865,0.000017737051,0.0002687029],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989102,0.00009365493,0.0002952858,0.00031137103,0.00018735522,0.00020212328],"domain_scores_gemma":[0.9991206,0.000016420414,0.00015191338,0.00051716005,0.00013158965,0.000062310995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020437452,0.00015883557,0.0002971622,0.00004804259,0.00006847876,0.000017845454,0.000230352,0.00012192667,0.000089815156],"category_scores_gemma":[0.000017531383,0.00013499417,0.000075820484,0.00015908755,0.00013478019,0.000008337645,0.00004320948,0.00008755436,0.000018225463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001283863,0.0002395691,0.28864315,0.0005779063,0.00007678144,5.822645e-7,0.00035163714,0.000038627604,0.7070475,0.000050930426,0.000093051465,0.0015963867],"study_design_scores_gemma":[0.0017384837,0.00077616004,0.14424385,0.00006292645,0.000028006423,0.000007717694,0.00012426652,0.00045242722,0.82706463,0.0000069184453,0.025203867,0.0002907217],"about_ca_topic_score_codex":0.000057383095,"about_ca_topic_score_gemma":0.00017177397,"teacher_disagreement_score":0.14439929,"about_ca_system_score_codex":0.0000061756527,"about_ca_system_score_gemma":0.000064803775,"threshold_uncertainty_score":0.55049026},"labels":[],"label_agreement":null},{"id":"W2986699028","doi":"10.1016/j.jchromb.2019.121853","title":"Efficient capture of monoclonal antibody from cell culture supernatant using protein A media contained in a cuboid packed-bed device","year":2019,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; National Research Council Canada; McMaster University","funders":"Science and Engineering Research Council; Natural Sciences and Engineering Research Council of Canada","keywords":"Cuboid; Chromatography; Chemistry; Packed bed; Elution; Volumetric flow rate; Monoclonal antibody; Analytical Chemistry (journal); Volume (thermodynamics); Protein purification; Affinity chromatography; Antibody; Biochemistry; Geometry; Mechanics; Physics; Biology","score_opus":0.007385508129645645,"score_gpt":0.2477886246167234,"score_spread":0.24040311648707777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2986699028","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943877,0.004561636,0.00035931857,0.00004814811,0.000100413294,0.00036010475,0.00007479469,0.000003226699,0.00010465497],"genre_scores_gemma":[0.99689114,0.000059886934,0.0028763465,0.000042778738,0.00006727979,0.0000032554442,0.00004156071,0.000012973311,0.0000047583367],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985585,0.00013180141,0.00060150406,0.00021898326,0.00030675714,0.00018242047],"domain_scores_gemma":[0.9988399,0.000016562613,0.00047888252,0.00028496716,0.00027905294,0.00010063308],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035925998,0.00016477374,0.00035055127,0.00013524744,0.000021676666,0.000016331165,0.000265789,0.00019135613,0.000041653762],"category_scores_gemma":[0.000064094114,0.00013051469,0.00025790685,0.00024560114,0.00007334416,0.0000070886163,0.000041545718,0.00021267841,0.000001289343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029580327,0.00025914327,0.04177923,0.00005036836,0.00005481621,0.000010957393,0.00043975827,0.00008520532,0.9569525,0.000030657335,0.000012573213,0.000028949022],"study_design_scores_gemma":[0.0031525958,0.00031522708,0.042275615,0.00022079238,0.00003951518,0.000038589264,0.0010429707,0.00055934547,0.9508694,0.00018295959,0.0010438103,0.00025921184],"about_ca_topic_score_codex":0.00012814479,"about_ca_topic_score_gemma":0.000030524297,"teacher_disagreement_score":0.006083168,"about_ca_system_score_codex":0.000021308857,"about_ca_system_score_gemma":0.00017796659,"threshold_uncertainty_score":0.53222346},"labels":[],"label_agreement":null},{"id":"W2992056814","doi":"10.1016/j.chroma.2019.460764","title":"Simulation and experimental study of the transport of protein bands through cuboid packed-bed devices during chromatographic separations","year":2019,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"McMaster University","keywords":"Cuboid; Chemistry; Packed bed; Chromatography; TRACER; Elution; Scaling; Flow (mathematics); Resolution (logic); Analytical Chemistry (journal); Mechanics; Biological system; Computer science; Geometry; Mechanical engineering; Physics; Engineering; Mathematics","score_opus":0.009894445807269702,"score_gpt":0.2726282040730156,"score_spread":0.26273375826574585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2992056814","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976571,0.0015113312,0.00007096188,0.00002059423,0.000042394913,0.0006147553,0.000007416079,0.0000030730957,0.000072358824],"genre_scores_gemma":[0.9997903,0.000017916607,0.00013563539,0.000007833646,0.000020841118,0.000011765705,0.0000025412146,0.0000083247005,0.0000048429],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989,0.0001010057,0.0005266382,0.00014227298,0.0002415276,0.00008854982],"domain_scores_gemma":[0.9989745,0.000011986662,0.0005431112,0.0002778369,0.000157998,0.000034586676],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019892964,0.000109970984,0.00022728114,0.000081422164,0.00006262694,0.0000078764415,0.00016192897,0.00007141622,0.000014058736],"category_scores_gemma":[0.000014190048,0.00007930772,0.00019801533,0.00025855767,0.000107883556,0.000024117007,0.000023404076,0.00007783914,1.0099543e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017607705,0.00089532754,0.25076145,0.0000931642,0.00015021543,4.4303124e-7,0.0011222803,0.00040711265,0.7463317,0.000049155115,0.0000010457969,0.000012065056],"study_design_scores_gemma":[0.0018045882,0.0011944224,0.35821518,0.000071135335,0.00004195083,0.000011574823,0.00149227,0.00005319505,0.6368394,0.00005381212,0.0001229138,0.00009956578],"about_ca_topic_score_codex":0.000010957486,"about_ca_topic_score_gemma":0.0000170703,"teacher_disagreement_score":0.109492294,"about_ca_system_score_codex":0.0000040605355,"about_ca_system_score_gemma":0.000044344106,"threshold_uncertainty_score":0.3234075},"labels":[],"label_agreement":null},{"id":"W2996930504","doi":"10.1016/j.pep.2019.105564","title":"Bacterial sugar-binding protein as a one-step affinity purification tag on dextran-containing resins","year":2019,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Affinity chromatography; Fusion protein; Biochemistry; Dextran; Protein purification; Chemistry; Tandem affinity purification; Chromatography; Recombinant DNA; Size-exclusion chromatography; Sepharose; FLAG-tag; Ligand (biochemistry); Enzyme; Receptor","score_opus":0.018850833713245457,"score_gpt":0.2595155638122643,"score_spread":0.24066473009901887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2996930504","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99047035,0.00027389053,0.0015198508,0.0008499488,0.00012570586,0.003226605,0.00003760686,0.00008371068,0.003412302],"genre_scores_gemma":[0.9916835,0.00006706918,0.0038603563,0.00008244485,0.00019335475,0.00088168704,0.00047081764,0.00004377631,0.0027169848],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973424,0.0004140392,0.0005238345,0.0009804502,0.00037392884,0.00036533782],"domain_scores_gemma":[0.99824405,0.00002759893,0.00036796223,0.000985943,0.00017573983,0.00019873197],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008774114,0.0003122964,0.00025815814,0.00012440306,0.00031336895,0.0001471191,0.0003155765,0.00039821118,0.0002793654],"category_scores_gemma":[0.0004231228,0.0003033693,0.00009468808,0.000162195,0.00009489444,0.000043374876,0.00008252949,0.0002847368,0.00020015633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011803459,0.00023264204,0.00042196826,0.000084655665,0.000014474864,4.3064475e-7,0.0001315745,0.000002208713,0.9856831,0.003082123,0.0000486824,0.009117837],"study_design_scores_gemma":[0.001206143,0.00055494806,0.0029503866,0.00019351984,0.000009492317,0.0000034130994,0.00016073558,0.000060940834,0.958909,0.0003730995,0.035188448,0.00038988492],"about_ca_topic_score_codex":0.000029582392,"about_ca_topic_score_gemma":0.000008860535,"teacher_disagreement_score":0.035139766,"about_ca_system_score_codex":0.000051642153,"about_ca_system_score_gemma":0.00013934924,"threshold_uncertainty_score":0.9999418},"labels":[],"label_agreement":null},{"id":"W3014158738","doi":"10.1021/acs.analchem.9b05385","title":"Comparative Analysis of One-Dimensional Protein Fingerprint by Line Shape Enhancement and Two-Dimensional <sup>1</sup>H,<sup>13</sup>C Methyl NMR Methods for Characterization of the Higher Order Structure of IgG1 Monoclonal Antibodies","year":2020,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"National Institute of Standards and Technology; Amgen","keywords":"Chemistry; Fingerprint (computing); Characterization (materials science); Resolution (logic); Nuclear magnetic resonance spectroscopy; Biopharmaceutical; Two-dimensional nuclear magnetic resonance spectroscopy; Line (geometry); Biological system; Proton NMR; Order (exchange); Analytical Chemistry (journal); Chromatography; Artificial intelligence; Stereochemistry; Computer science; Mathematics; Optics; Physics; Geometry","score_opus":0.02505718197098887,"score_gpt":0.32146203911206783,"score_spread":0.29640485714107895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3014158738","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99239504,0.00029865632,0.0054099113,0.0008292075,0.0000054415464,0.00039927335,0.0006158204,0.0000049890245,0.00004164739],"genre_scores_gemma":[0.9870913,0.000008911491,0.011566897,0.00015746058,0.00004631574,0.000024242929,0.0009494192,0.0000104309265,0.00014501128],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99823916,0.00013605399,0.00064434024,0.0005201241,0.00027900274,0.00018129684],"domain_scores_gemma":[0.9985614,0.00008574448,0.00034686076,0.00035748404,0.00053566584,0.000112844726],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025989933,0.00022876199,0.00062311796,0.000028173665,0.00006106005,0.000009748723,0.00021616623,0.00018766655,0.00035445218],"category_scores_gemma":[0.0002690433,0.0001808865,0.00023738047,0.00036944897,0.00037028498,0.000008614159,0.00019610944,0.00015306404,1.9521072e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003659161,0.00018673445,0.0006781504,0.0001839922,0.001050814,7.213355e-8,0.00010629829,0.003974122,0.9929025,0.000079534315,0.000027312764,0.00044453592],"study_design_scores_gemma":[0.00045979288,0.000083255654,0.0012550054,0.000018295674,0.00036484064,2.9688255e-7,0.00002362419,0.21994136,0.77731663,0.00006962255,0.000330542,0.00013673534],"about_ca_topic_score_codex":0.000011168999,"about_ca_topic_score_gemma":7.575819e-7,"teacher_disagreement_score":0.21596724,"about_ca_system_score_codex":0.000015953992,"about_ca_system_score_gemma":0.00011354644,"threshold_uncertainty_score":0.73763376},"labels":[],"label_agreement":null},{"id":"W3014443303","doi":"10.1002/bit.27349","title":"Highland games: A benchmarking exercise in predicting biophysical and drug properties of monoclonal antibodies from amino acid sequences","year":2020,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Benchmarking; Competitor analysis; Biopharmaceutical; Isoelectric point; Competition (biology); Computer science; Isoelectric focusing; Biochemical engineering; Computational biology; Chemistry; Business; Biotechnology; Biology; Biochemistry; Marketing; Engineering; Ecology","score_opus":0.010807995737785854,"score_gpt":0.19902956508327752,"score_spread":0.18822156934549167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3014443303","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.986872,0.011747096,0.00040065992,0.0007856172,0.00002374065,0.00011829791,0.000019161767,0.000030727235,0.0000026904722],"genre_scores_gemma":[0.99652916,0.0018280089,0.0015614001,0.000015861502,0.000036498768,0.000011178788,0.000011168035,0.000005410829,0.0000013174748],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993776,0.000012621521,0.00016729362,0.00027946229,0.000042554115,0.000120479046],"domain_scores_gemma":[0.99980044,0.0000055124187,0.00004239311,0.000102437545,0.000013489449,0.000035699195],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000627878,0.0001078529,0.00016097944,0.00004150583,0.00002619882,0.0000090616695,0.000084405256,0.0001676858,0.0000011036252],"category_scores_gemma":[0.000047881727,0.00009268142,0.000019413534,0.000080740705,0.00021932302,0.000006833028,0.00010982282,0.00010733214,1.6959659e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004336274,0.000012912776,0.020642836,0.00007996722,0.000016646249,0.0000014155265,0.00024316722,0.000010178274,0.97534716,0.000047903075,0.0000016661775,0.003552801],"study_design_scores_gemma":[0.00020592836,0.00006771725,0.013415877,0.00009924716,0.000009354773,0.0000022867243,0.0002333538,0.0039892145,0.98167026,0.000025103855,0.00016748453,0.00011417822],"about_ca_topic_score_codex":0.000051235176,"about_ca_topic_score_gemma":0.000010037679,"teacher_disagreement_score":0.0099190865,"about_ca_system_score_codex":0.000003545319,"about_ca_system_score_gemma":0.000013659677,"threshold_uncertainty_score":0.37794384},"labels":[],"label_agreement":null},{"id":"W3016217076","doi":"10.1007/s10450-020-00220-9","title":"Modelling binary non-linear chromatography using discrete equilibrium data","year":2020,"lang":"en","type":"article","venue":"Adsorption","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Binary number; Adsorption; Elution; Work (physics); Phase (matter); Range (aeronautics); Thermodynamics; Ideal (ethics); Chemistry; Chromatography; Biological system; Applied mathematics; Mathematics; Materials science; Physics; Physical chemistry; Organic chemistry","score_opus":0.07125994314273093,"score_gpt":0.3005128580615379,"score_spread":0.22925291491880695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016217076","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.73328155,0.00043046277,0.2655859,0.00031621486,0.000046709658,0.00016152849,0.00005615726,0.000022451164,0.00009902244],"genre_scores_gemma":[0.99152684,0.00007034008,0.006943253,0.0002148191,0.00023339066,0.0000053352874,0.0009790156,0.000015291083,0.00001169945],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9991397,0.000041747022,0.00016661307,0.00041859882,0.000096395685,0.00013693633],"domain_scores_gemma":[0.99923116,0.000002919404,0.00006199513,0.0005779931,0.00003893236,0.00008697827],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013234637,0.000098425866,0.00008658621,0.000018168334,0.000039191807,0.000017268547,0.00026489518,0.00008767474,0.000016023781],"category_scores_gemma":[0.000027846258,0.00009975068,0.000050541606,0.00011736146,0.000046047055,0.000015740843,0.00020337607,0.000066823515,0.000014622418],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006914384,0.000024602068,0.0012036029,0.000031409825,0.000018734901,5.721519e-7,0.00003730341,0.013896321,0.98434734,0.000020455569,0.0001374945,0.00021302329],"study_design_scores_gemma":[0.00021965671,0.00007855835,0.000189714,0.0000071522236,0.000014483805,0.0000021714457,0.000025999803,0.9527845,0.040628187,0.000037405734,0.005870507,0.00014169561],"about_ca_topic_score_codex":0.000019460489,"about_ca_topic_score_gemma":7.043343e-7,"teacher_disagreement_score":0.94371915,"about_ca_system_score_codex":0.0000047952453,"about_ca_system_score_gemma":0.000037801034,"threshold_uncertainty_score":0.40677145},"labels":[],"label_agreement":null},{"id":"W3020339550","doi":"10.1039/d0cp00404a","title":"Inter-protein interactions govern protein loading into porous vaterite CaCO<sub>3</sub> crystals","year":2020,"lang":"en","type":"article","venue":"Physical Chemistry Chemical Physics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Bijzonder Onderzoeksfonds UGent; Universiteit Gent; Trent University; Fonds Wetenschappelijk Onderzoek; H2020 Marie Skłodowska-Curie Actions; Nottingham Trent University; Lomonosov Moscow State University; Alexander von Humboldt-Stiftung","keywords":"Vaterite; Protein crystallization; Chemistry; Chemical engineering; Nanoparticle; Protein aggregation; Biophysics; Crystallography; Whey protein; Materials science; Nanotechnology; Chromatography; Calcium carbonate; Biochemistry; Organic chemistry","score_opus":0.01238221379166569,"score_gpt":0.24310345467771258,"score_spread":0.2307212408860469,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3020339550","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905463,0.00006208981,0.006458116,0.0011090328,0.000026670816,0.00044986335,0.00009155428,0.00011434477,0.001142068],"genre_scores_gemma":[0.99706906,0.0000043122604,0.00030225905,0.00035805732,0.0014841795,0.0002182075,0.00040851775,0.000067222616,0.000088177025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977976,0.00005283445,0.0004200689,0.0009607203,0.0003149541,0.00045383335],"domain_scores_gemma":[0.99851406,0.000021175709,0.00021580036,0.00065431115,0.00017722475,0.00041743385],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007384186,0.00044370192,0.0003998327,0.000006098426,0.000111457644,0.000078430625,0.0005063452,0.00018873127,0.000026249623],"category_scores_gemma":[0.0003158321,0.00046996813,0.00031423467,0.00022291744,0.00025717096,0.000031630985,0.00041558253,0.00054572144,0.000070836344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016771954,0.00038110983,0.000013404089,0.00026178203,0.00006658371,0.0000031506304,0.00015950277,0.000009416214,0.99415594,0.00008005266,0.00028248635,0.0044188243],"study_design_scores_gemma":[0.00045398617,0.000064699416,0.000006821893,0.000049963637,0.000024416433,0.0000032319524,0.000042717867,0.00051555806,0.9919323,0.0027117692,0.0036755914,0.00051897956],"about_ca_topic_score_codex":0.000010275955,"about_ca_topic_score_gemma":5.144591e-7,"teacher_disagreement_score":0.006522807,"about_ca_system_score_codex":0.00010993159,"about_ca_system_score_gemma":0.00008347522,"threshold_uncertainty_score":0.99977523},"labels":[],"label_agreement":null},{"id":"W3021693745","doi":"10.1002/elps.201900449","title":"Optimization of an IgG1 CIEF separation by using narrow‐range ampholytes and DMSO as protein solubilizer","year":2020,"lang":"en","type":"article","venue":"Electrophoresis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"SCIEX","keywords":"Chemistry; Chromatography; Resolution (logic); High resolution; Capillary action; Solubilization; Isoelectric focusing; Precipitation; Analytical Chemistry (journal); Materials science; Computer science; Biochemistry; Artificial intelligence","score_opus":0.010621908128291335,"score_gpt":0.26036508750450693,"score_spread":0.2497431793762156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3021693745","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98749757,0.0026757054,0.008920181,0.0003715212,0.000007655422,0.00038992215,0.00001801399,0.000013908776,0.00010551456],"genre_scores_gemma":[0.99578154,0.00009829231,0.003630211,0.00023379418,0.00004380372,0.00002843906,0.000117323994,0.000015133213,0.000051467083],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99914986,0.00010003698,0.00018023976,0.00032017744,0.000111793815,0.00013792275],"domain_scores_gemma":[0.99953264,0.000004814447,0.00009018783,0.00019321706,0.000090417016,0.000088698565],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011254676,0.000106286185,0.000116169474,0.000017963337,0.00007257222,0.00002187298,0.0000909243,0.000105977495,0.00004534609],"category_scores_gemma":[0.00015654288,0.00010807533,0.000034765635,0.000118590295,0.000065959626,0.0000103216325,0.00002468449,0.000050986044,9.9952e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020265736,0.00005194491,0.00017895184,0.000021810882,0.000011681351,2.6499166e-7,0.00008360055,0.000315453,0.99826294,0.000026120053,0.00016324304,0.00068135944],"study_design_scores_gemma":[0.0003012969,0.0005799493,0.00014244307,0.0000029278401,0.000012367797,0.0000024532494,0.000025754181,0.010779479,0.9858785,0.000045701425,0.0020994786,0.00012963964],"about_ca_topic_score_codex":0.0000393091,"about_ca_topic_score_gemma":0.000005221689,"teacher_disagreement_score":0.012384403,"about_ca_system_score_codex":0.0000124413955,"about_ca_system_score_gemma":0.000066975976,"threshold_uncertainty_score":0.4407184},"labels":[],"label_agreement":null},{"id":"W3027685334","doi":"10.1016/bs.mie.2020.04.066","title":"Glutamine-walking: Creating reactive substrates for transglutaminase-mediated protein labeling","year":2020,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; PROTEO; Centre in Green Chemistry and Catalysis","funders":"","keywords":"Glutamine; Chemistry; Biochemistry; Tissue transglutaminase; Enzyme; Moiety; Fluorophore; Amino acid; Substrate (aquarium); Combinatorial chemistry; Biology; Stereochemistry; Fluorescence","score_opus":0.060000124075474295,"score_gpt":0.3992836415847424,"score_spread":0.3392835175092681,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3027685334","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7145252,0.0024886946,0.27657676,0.0016767359,0.00045666308,0.0027012124,0.00010895749,0.0001230827,0.0013426677],"genre_scores_gemma":[0.37167147,0.000071529015,0.625473,0.0011376542,0.00019725012,0.0010953902,0.00016502915,0.000083984574,0.00010469011],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9866941,0.008367758,0.0015483323,0.0019992692,0.00019287245,0.0011976921],"domain_scores_gemma":[0.9948536,0.003218561,0.00051861815,0.00089115807,0.00023566664,0.00028236725],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.007925368,0.0007160017,0.0012855977,0.00038210064,0.00018502353,0.00003149327,0.00082786166,0.0014386819,0.000089223366],"category_scores_gemma":[0.017922599,0.0007508785,0.00029315587,0.0008404859,0.0006392711,0.000022842325,0.00018426789,0.0011701424,0.000009993203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00146472,0.000432094,0.0021833184,0.00013534482,0.00008761868,0.00004328114,0.0010508582,0.00018351144,0.9464125,0.0019523457,0.000026165635,0.046028227],"study_design_scores_gemma":[0.0046382975,0.0030506689,0.024125839,0.000082422,0.000058390393,0.00007539499,0.00096166384,0.0012553886,0.94191927,0.009193936,0.0134957535,0.0011429684],"about_ca_topic_score_codex":0.00009386594,"about_ca_topic_score_gemma":0.0002903554,"teacher_disagreement_score":0.34889624,"about_ca_system_score_codex":0.0001367887,"about_ca_system_score_gemma":0.00026103025,"threshold_uncertainty_score":0.99985766},"labels":[],"label_agreement":null},{"id":"W3033370517","doi":"10.1039/d0ce00642d","title":"Protein crystal occurrence domains in selective protein crystallisation for bio-separation","year":2020,"lang":"en","type":"article","venue":"CrystEngComm","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Kensington Health","funders":"Engineering and Physical Sciences Research Council","keywords":"Bottleneck; Protein crystallization; Crystallization; Separation (statistics); Key (lock); Protein purification; Separation method; Chemistry; Materials science; Chromatography; Nanotechnology; Computer science; Organic chemistry; Machine learning","score_opus":0.024389546674928934,"score_gpt":0.284268557747363,"score_spread":0.25987901107243405,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033370517","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9061905,0.00028658772,0.08655553,0.001976006,0.000040664992,0.004072937,0.00018316894,0.000051679115,0.00064293033],"genre_scores_gemma":[0.99600923,0.0000038310613,0.0019727582,0.00020527028,0.00012656504,0.0011875625,0.0004029359,0.0000147496385,0.00007708136],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99860936,0.00016169738,0.00034172492,0.0005035119,0.00013638643,0.0002473311],"domain_scores_gemma":[0.99929243,0.000013658141,0.00013350669,0.00027931592,0.00017311392,0.00010796566],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003316549,0.00017359095,0.00017021065,0.000040437535,0.00010286309,0.000041148032,0.00020574014,0.00016654572,0.000013002193],"category_scores_gemma":[0.0005603408,0.00017847914,0.00008566288,0.00021376889,0.000069862974,0.000016300351,0.000051601626,0.00012722783,0.000005993707],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036818994,0.000102298334,0.0006133132,0.00010986125,0.000013114755,5.643222e-7,0.00035818078,0.00005674392,0.9960314,0.0008102304,0.00034024476,0.0011958411],"study_design_scores_gemma":[0.0035185406,0.0014626635,0.003184098,0.000064318694,0.000017040094,0.0000039238107,0.00050000363,0.0037229392,0.86598676,0.0016269858,0.119162016,0.0007507075],"about_ca_topic_score_codex":0.000008934716,"about_ca_topic_score_gemma":0.000050520415,"teacher_disagreement_score":0.13004465,"about_ca_system_score_codex":0.000048940587,"about_ca_system_score_gemma":0.00014914742,"threshold_uncertainty_score":0.72781676},"labels":[],"label_agreement":null},{"id":"W3034655230","doi":"10.1021/acsabm.0c00324","title":"Elucidating the Role of Thermal Flexibility of Hydrogels in Protein Refolding","year":2020,"lang":"en","type":"article","venue":"ACS Applied Bio Materials","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Prince Edward Island","funders":"Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Self-healing hydrogels; Chemistry; Methacrylamide; Biophysics; Lysozyme; Polymerization; Radical polymerization; Monomer; Biochemistry; Polymer chemistry; Polymer; Organic chemistry","score_opus":0.015057532269090592,"score_gpt":0.23901661115068537,"score_spread":0.22395907888159478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3034655230","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99820626,0.00016014297,0.000053633757,0.00015246222,0.00001082078,0.00063320494,0.000039193317,0.0000069735124,0.00073731464],"genre_scores_gemma":[0.9994094,0.0000062443773,0.00034102556,0.00006890078,0.000048758047,0.00008422397,0.00002969556,0.000008738908,0.0000030175124],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990415,0.00009564013,0.00040552107,0.00024101985,0.00009454235,0.00012180315],"domain_scores_gemma":[0.99937886,0.00000873154,0.00020260585,0.00035081452,0.00003287623,0.000026085097],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006152736,0.00009206984,0.00018118702,0.000010572242,0.000024903677,0.000009216521,0.00024283303,0.00009165248,0.000039101866],"category_scores_gemma":[0.000114770264,0.00006688136,0.000027259732,0.00008520201,0.00009819979,0.0000023973755,0.00012989019,0.000040212104,0.0000024146304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016744233,0.000034101187,0.00025198792,0.000050266914,0.000009460777,5.5554096e-8,0.00014317072,0.000010365228,0.99561554,0.0011279942,0.0000011663427,0.0025884446],"study_design_scores_gemma":[0.000192219,0.00004475264,0.0012257389,0.0000068275535,0.000003338798,1.4339285e-7,0.00014438595,0.000004667556,0.99719274,0.00045850678,0.00065839157,0.00006830792],"about_ca_topic_score_codex":0.000029093118,"about_ca_topic_score_gemma":0.000002649269,"teacher_disagreement_score":0.0025201368,"about_ca_system_score_codex":0.0000057125308,"about_ca_system_score_gemma":0.000035125035,"threshold_uncertainty_score":0.27273425},"labels":[],"label_agreement":null},{"id":"W3035851635","doi":"10.1371/journal.pcbi.1007942","title":"Moving analytical ultracentrifugation software to a good manufacturing practices (GMP) environment","year":2020,"lang":"en","type":"article","venue":"PLoS Computational Biology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Analytical Ultracentrifugation; Software; Computer science; Workflow; Biopharmaceutical; Instrumentation (computer programming); Software engineering; Ultracentrifuge; Chemistry","score_opus":0.031055396785003676,"score_gpt":0.2758552806157006,"score_spread":0.2447998838306969,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3035851635","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.70390475,0.00016184204,0.28818187,0.0070468374,0.000037588343,0.00039081316,0.000068635134,0.000040005787,0.0001676321],"genre_scores_gemma":[0.97127235,0.000011015761,0.026323602,0.0017013432,0.00016124942,0.000034795954,0.00046369815,0.000009855391,0.00002209221],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989511,0.00008862467,0.00022435958,0.00044773825,0.00011880335,0.0001693751],"domain_scores_gemma":[0.99942726,0.00007837326,0.00015254572,0.00013779188,0.000046386478,0.00015762997],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010909308,0.00011670931,0.0001181717,0.000026434427,0.00008126319,0.000020075531,0.00015055563,0.00010273137,0.00008756981],"category_scores_gemma":[0.00069682597,0.00011542255,0.00005060757,0.00004793189,0.000048678336,0.000006326303,0.0000922724,0.00009255139,0.00009154705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00076749094,0.00094982266,0.05360222,0.00013088739,0.00047323294,0.000005661936,0.0005693278,0.09348683,0.8165857,0.005959502,0.00052650314,0.026942808],"study_design_scores_gemma":[0.0029134003,0.0022457545,0.1379734,0.000029472007,0.0001479043,0.000037885788,0.00031373493,0.06688531,0.50229,0.003449251,0.28217793,0.0015359465],"about_ca_topic_score_codex":0.0000031112586,"about_ca_topic_score_gemma":8.9485223e-7,"teacher_disagreement_score":0.31429568,"about_ca_system_score_codex":0.00002414031,"about_ca_system_score_gemma":0.00005063635,"threshold_uncertainty_score":0.47067946},"labels":[],"label_agreement":null},{"id":"W3043690423","doi":"10.1016/j.xphs.2020.07.012","title":"Method to Determine Syringe Silicone Oil Layer Heterogeneity and Investigation of its Impact on Product Particle Counts","year":2020,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Donna and Benjamin M. Rosen Bioengineering Center, California Institute of Technology; National Institutes of Health; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Amgen","keywords":"Silicone oil; Syringe; Silicone; Extrusion; Materials science; Particle-size distribution; Particle (ecology); Lubrication; Particle size; Composite material; Chromatography; Biomedical engineering; Chemical engineering; Chemistry; Medicine","score_opus":0.12351536425395496,"score_gpt":0.43006909266730525,"score_spread":0.30655372841335027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3043690423","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99686056,0.0006698266,0.00024458338,0.00205328,0.000021695656,0.00003803573,0.0000038212515,0.0000012616779,0.00010694853],"genre_scores_gemma":[0.998017,0.00005950768,0.0012998999,0.00055095,0.00006483346,8.4204737e-7,1.881922e-7,0.0000014375204,0.000005350528],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99946564,0.00007721125,0.00014473447,0.00010599085,0.00013423464,0.00007216705],"domain_scores_gemma":[0.99964577,0.00001691904,0.00006578166,0.000038268703,0.00006804349,0.00016523189],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005981105,0.00004113998,0.0000739526,0.000011028703,0.000024546682,0.0000085446845,0.0000861353,0.000016027374,0.000020554493],"category_scores_gemma":[0.00020050483,0.0000275463,0.000028689712,0.00009177602,0.00007441411,0.0000072450225,0.000023707884,0.00004407494,0.0000024857052],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000066369226,0.000016855503,0.007863207,0.000013856951,0.000006974721,3.9444782e-7,0.00003155132,0.00005155246,0.9740724,0.000023858138,0.000031872005,0.017821122],"study_design_scores_gemma":[0.00012409192,0.00034847003,0.012690949,0.000005685079,0.000006768841,0.000006173745,0.0000051756733,0.0010397355,0.9831683,0.000014901082,0.0025562935,0.0000334425],"about_ca_topic_score_codex":6.7973133e-7,"about_ca_topic_score_gemma":3.5209098e-7,"teacher_disagreement_score":0.01778768,"about_ca_system_score_codex":0.0000051226566,"about_ca_system_score_gemma":0.000044527686,"threshold_uncertainty_score":0.112330556},"labels":[],"label_agreement":null},{"id":"W3081700693","doi":"10.1016/j.chroma.2020.461524","title":"High-resolution purification of a therapeutic PEGylated protein using a cuboid packed-bed device","year":2020,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Bristol-Myers Squibb","keywords":"Cuboid; Packed bed; Elution; Chromatography; Polyethylene glycol; PEG ratio; Chemistry; PEGylation; Yield (engineering); Resolution (logic); Materials science; Biochemistry; Composite material","score_opus":0.02527931982089699,"score_gpt":0.2617194496029282,"score_spread":0.23644012978203122,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3081700693","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9841677,0.0029252477,0.011895523,0.0006287624,0.00003963714,0.00029690342,0.000010312926,0.000008418932,0.000027494283],"genre_scores_gemma":[0.99459463,0.000077428405,0.0050619366,0.00013190105,0.00010153123,0.0000064617607,0.000011598771,0.000012763147,0.000001747583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987551,0.00016907448,0.0005544455,0.00016562692,0.00022570365,0.00013004258],"domain_scores_gemma":[0.99861574,0.0000072066823,0.00068223337,0.00021117635,0.0003767527,0.000106907726],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003204169,0.00011960061,0.00022534082,0.00009036428,0.000049120114,0.000016627368,0.00020081969,0.00012293084,0.00001820512],"category_scores_gemma":[0.00009902354,0.00010535392,0.00022393548,0.00037994885,0.00009310237,0.00001401185,0.000021248057,0.00012273662,9.944276e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029396472,0.00011707297,0.0010234116,0.000070965274,0.00011533124,0.0000012397742,0.0001212807,0.00004167212,0.9969514,0.0002564698,0.000027234351,0.0009799448],"study_design_scores_gemma":[0.0010928812,0.00065174577,0.0090863565,0.0000623317,0.00007123797,0.000034073146,0.00012670993,0.00052788306,0.98505217,0.00046591883,0.0026671416,0.00016158004],"about_ca_topic_score_codex":0.000010384149,"about_ca_topic_score_gemma":0.0000018288376,"teacher_disagreement_score":0.011899273,"about_ca_system_score_codex":0.000011638444,"about_ca_system_score_gemma":0.00013782224,"threshold_uncertainty_score":0.42962083},"labels":[],"label_agreement":null},{"id":"W3082257154","doi":"10.18433/jpps31424","title":"Biowaiver for Immediate and Modified Release Dosage forms Scientific summary of the CSPS workshop","year":2020,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Dosage form; Bioequivalence; Immediate release; Active ingredient; Medicine; Pharmacology; Bioavailability","score_opus":0.08292671490511838,"score_gpt":0.3711271928273344,"score_spread":0.28820047792221604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3082257154","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98026985,0.006644043,0.0016366314,0.010552156,0.0003546985,0.00033978058,0.000033256638,0.0000034578652,0.0001661185],"genre_scores_gemma":[0.9980539,0.0004995611,0.00040670641,0.00083586306,0.00014108379,0.000005026621,0.0000018211887,0.000004635146,0.000051383726],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876547,0.000092042974,0.00037718355,0.00023840491,0.00031928197,0.00020761686],"domain_scores_gemma":[0.9991584,0.00007069139,0.00024134592,0.00010536257,0.00016949339,0.0002547261],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011353226,0.00009904879,0.00014320896,0.00003258709,0.00022198257,0.000059692185,0.00049684435,0.000035151712,0.00002514082],"category_scores_gemma":[0.00049398607,0.000059221205,0.000151099,0.0002820056,0.000970841,0.000030241006,0.00013731583,0.00015164992,5.744113e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005405549,0.00010665956,0.0044565927,0.00007016213,0.000031616986,0.0000012600202,0.00015880387,0.00009109773,0.9568536,0.00039884698,0.0011222836,0.03616847],"study_design_scores_gemma":[0.001857869,0.00015500773,0.0009085029,0.000017599848,0.00006248655,0.000010850884,0.00012142119,0.0074770767,0.79693687,0.0003889463,0.19193591,0.00012747511],"about_ca_topic_score_codex":0.0000011332917,"about_ca_topic_score_gemma":7.8681273e-7,"teacher_disagreement_score":0.19081362,"about_ca_system_score_codex":0.0000088969955,"about_ca_system_score_gemma":0.00020410595,"threshold_uncertainty_score":0.35771042},"labels":[],"label_agreement":null},{"id":"W3096200300","doi":"10.5539/ijc.v12n2p45","title":"Enhancement of Lytic Activity of HEWL Adsorbed on Biochar by the Optimization of Adsorption Conditions","year":2020,"lang":"en","type":"article","venue":"International Journal of Chemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Biochar; Chemistry; Adsorption; Lysozyme; Lytic cycle; Chromatography; Inorganic chemistry; Chemical engineering; Organic chemistry; Biochemistry; Pyrolysis","score_opus":0.012067620383764008,"score_gpt":0.271000616883217,"score_spread":0.258932996499453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3096200300","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98015934,0.00021815054,0.017691584,0.0013877619,0.000053746633,0.000065817745,0.00012273937,0.0000011484683,0.0002996963],"genre_scores_gemma":[0.9994271,0.00013206844,0.00017949409,0.000079795274,0.00007581277,0.0000028975587,0.000062567626,0.0000042190895,0.00003608235],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992085,0.000031406085,0.000353397,0.00008798983,0.00027496446,0.000043739354],"domain_scores_gemma":[0.99867636,0.000021582398,0.00064245355,0.00011486821,0.00050937023,0.000035394416],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014394902,0.00006249109,0.00011392808,0.000013319333,0.000009440686,0.000004036029,0.0002534003,0.000057152218,0.00016577957],"category_scores_gemma":[0.00023246236,0.00005076988,0.000103017504,0.000046588142,0.000092862465,0.000006575425,0.000029139714,0.000074741154,4.4415256e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032629416,0.00019533886,0.00009975263,0.000031342817,0.00010072065,1.7358332e-7,0.000057585064,0.0015099609,0.99705833,0.00001977095,0.0003165116,0.00028423272],"study_design_scores_gemma":[0.0004530289,0.00014374587,0.00018399405,0.0000302587,0.000014467294,0.000004373804,0.00005105675,0.00036941553,0.9983158,0.000031531155,0.00036355172,0.000038793172],"about_ca_topic_score_codex":0.0000019456722,"about_ca_topic_score_gemma":1.2988797e-7,"teacher_disagreement_score":0.019267708,"about_ca_system_score_codex":0.000018398841,"about_ca_system_score_gemma":0.00008036365,"threshold_uncertainty_score":0.20703356},"labels":[],"label_agreement":null},{"id":"W3099727108","doi":"10.1007/s00249-020-01483-4","title":"Analytical ultracentrifugation: still the gold standard that offers multiple solutions","year":2020,"lang":"en","type":"article","venue":"European Biophysics Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"Biomolecular Interaction Centre, University of Canterbury; Riddet Institute; Maurice Wilkins Centre for Molecular Biodiscovery; University of Canterbury","keywords":"Analytical Ultracentrifugation; Isothermal titration calorimetry; Nanotechnology; Protein chemistry; Chemistry; Ultracentrifuge; Polymer science; Materials science; Physical chemistry; Chromatography; Biochemistry","score_opus":0.0473103217466971,"score_gpt":0.24408197663993417,"score_spread":0.19677165489323706,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3099727108","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86260414,0.0015368796,0.10090228,0.02505823,0.0005148623,0.00054515956,0.00022527395,0.000068735826,0.008544429],"genre_scores_gemma":[0.99748236,0.00018588323,0.00026017887,0.0011057734,0.0007923883,0.0000015021445,0.00003412887,0.000018666438,0.00011911149],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99879366,0.00031595427,0.00021493292,0.00022406336,0.00022902583,0.00022235299],"domain_scores_gemma":[0.9992374,0.000019338897,0.000124142,0.00026970982,0.00014533276,0.00020406477],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042274233,0.00012439345,0.00009905935,0.000011668468,0.00023483661,0.000112194015,0.0003305755,0.00003364314,0.000033785902],"category_scores_gemma":[0.00027350933,0.00008910504,0.00015063495,0.00012114061,0.00015985745,0.000009511107,0.00008579744,0.00028343961,0.000062144936],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017867277,0.00061976997,0.037126176,0.000067040906,0.0007583855,0.00010352271,0.0026742,0.0021174469,0.80626833,0.0062457556,0.07238631,0.06984635],"study_design_scores_gemma":[0.0021470205,0.00061895075,0.035326194,0.000019558638,0.00009342239,0.000086608125,0.0007788123,0.0029863014,0.0765529,0.00027755369,0.8805559,0.00055674976],"about_ca_topic_score_codex":7.0240606e-7,"about_ca_topic_score_gemma":6.407735e-7,"teacher_disagreement_score":0.8081696,"about_ca_system_score_codex":0.000018782444,"about_ca_system_score_gemma":0.00007292858,"threshold_uncertainty_score":0.3633598},"labels":[],"label_agreement":null},{"id":"W3112602608","doi":"10.1021/acsomega.0c04692","title":"Effects of Excipients on the Structure and Dynamics of Filgrastim Monitored by Thermal Unfolding Studies by CD and NMR Spectroscopy","year":2020,"lang":"en","type":"article","venue":"ACS Omega","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Nuclear magnetic resonance spectroscopy; Dynamics (music); Filgrastim; Chemistry; Spectroscopy; Nuclear magnetic resonance; Stereochemistry; Organic chemistry; Physics; Toxicity","score_opus":0.006841291785139904,"score_gpt":0.24177637152538414,"score_spread":0.23493507974024425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112602608","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99444664,0.004625174,0.00007498046,0.00052771164,0.000021640279,0.00018361142,0.00010068106,0.0000030193341,0.000016551621],"genre_scores_gemma":[0.9994306,0.00032680834,0.00006527042,0.0001108855,0.00001670277,0.000004971091,0.000028406834,0.0000057917864,0.000010593625],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99954206,0.000044025568,0.00010337725,0.00016199723,0.000072000534,0.000076548546],"domain_scores_gemma":[0.9997038,0.000044209843,0.0000695822,0.000117831,0.00003254142,0.000032004238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000048280235,0.00008275065,0.00011674705,0.0000062092945,0.00003926996,0.000006050254,0.000082057755,0.000054785873,6.521725e-7],"category_scores_gemma":[0.00016210758,0.000057198846,0.000016588665,0.000040960367,0.00013701597,0.000002204297,0.0000611206,0.00005441405,7.843687e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006643956,0.000017749326,0.00433984,0.0000756272,0.00005053424,1.1399501e-7,0.00014514831,0.0000021421283,0.9943276,0.000084015395,0.0003790896,0.00051169586],"study_design_scores_gemma":[0.00028659892,0.0002522085,0.005922311,0.000010240215,0.000013038694,2.3675582e-7,0.00012156066,0.000085074586,0.99296767,0.000106937325,0.00017682777,0.000057276884],"about_ca_topic_score_codex":0.0000036829226,"about_ca_topic_score_gemma":0.0000010357342,"teacher_disagreement_score":0.0049839397,"about_ca_system_score_codex":0.000005228249,"about_ca_system_score_gemma":0.0000068714653,"threshold_uncertainty_score":0.23325013},"labels":[],"label_agreement":null},{"id":"W3121626024","doi":"10.1021/acsomega.0c05481","title":"Phage-Display-Derived Peptide Specific to Carbamylated Protein","year":2021,"lang":"en","type":"article","venue":"ACS Omega","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Alberta","funders":"","keywords":"Isothermal titration calorimetry; Peptide; Dissociation constant; Chemistry; Human serum albumin; Biochemistry; Receptor","score_opus":0.013177047399241856,"score_gpt":0.2472127064295853,"score_spread":0.23403565903034343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3121626024","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921887,0.0013726422,0.0010741896,0.0009930376,0.000091452705,0.00039402882,0.000028439923,0.000029374238,0.0038281623],"genre_scores_gemma":[0.99214816,0.000052308395,0.0015129406,0.00043697585,0.00012597676,0.00010154444,0.0001773821,0.000019581163,0.0054251403],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888784,0.00008373125,0.00019616364,0.00046528943,0.00013115372,0.00023583049],"domain_scores_gemma":[0.9989756,0.0000056573585,0.00004122933,0.0006678576,0.0001725289,0.00013716694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014206629,0.00013527047,0.00012689571,0.000024339648,0.00007960545,0.000040034465,0.00018546746,0.000117750504,0.000054611082],"category_scores_gemma":[0.00016777487,0.00013871328,0.00006675326,0.00019138807,0.000041944313,0.0000037067105,0.00011860815,0.000091592156,0.00013213242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045622408,0.000069871596,0.00022385387,0.000010268699,0.000019767465,0.000011591452,0.000052344698,0.0000059267527,0.99536693,0.00023896561,0.0015562047,0.0023986686],"study_design_scores_gemma":[0.0002562002,0.000052487092,0.0033989316,0.0000062779095,0.0000029454668,0.0000065938384,0.00004908839,0.0000029374564,0.7296312,0.00007512103,0.26637864,0.00013956997],"about_ca_topic_score_codex":0.000009198497,"about_ca_topic_score_gemma":0.000028016097,"teacher_disagreement_score":0.26573572,"about_ca_system_score_codex":0.00002156393,"about_ca_system_score_gemma":0.00010068123,"threshold_uncertainty_score":0.56565636},"labels":[],"label_agreement":null},{"id":"W3129007842","doi":"10.3389/fbioe.2021.630551","title":"Challenges Associated With the Formation of Recombinant Protein Inclusion Bodies in Escherichia coli and Strategies to Address Them for Industrial Applications","year":2021,"lang":"en","type":"review","venue":"Frontiers in Bioengineering and Biotechnology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":297,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; University of Waterloo; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada","keywords":"Inclusion bodies; Escherichia coli; Recombinant DNA; Inclusion (mineral); Host (biology); Mechanism (biology); Computational biology; Biology; Biochemical engineering; Chemistry; Biotechnology; Biochemistry; Genetics; Gene; Engineering","score_opus":0.039459580137435224,"score_gpt":0.2700569645048063,"score_spread":0.2305973843673711,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3129007842","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0033073162,0.9824749,0.011300322,0.0006583583,0.000054024244,0.0021414715,0.000036607027,0.000016347762,0.000010641508],"genre_scores_gemma":[0.025053581,0.97098917,0.0022560286,0.0000045965985,0.000016681222,0.0015377576,0.000111232664,0.00001585158,0.000015120815],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991842,0.00006643624,0.00026743996,0.00028454384,0.00004741799,0.00014996505],"domain_scores_gemma":[0.9995635,0.00002096598,0.00013405136,0.00022456024,0.000036903915,0.000019985451],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035399746,0.00016960598,0.00047620802,0.00012833248,0.000059369675,0.000012582004,0.00015956028,0.000612642,1.3738092e-7],"category_scores_gemma":[0.00011252615,0.00011997919,0.000035900215,0.00019672667,0.00010973311,0.0000051241436,0.00020613005,0.00020834526,2.5370536e-8],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045901914,0.00009499619,0.000013475958,0.0025533363,0.00008982706,6.3426387e-7,0.00023826453,0.00001796695,0.0015670249,0.0015635577,0.00008107942,0.99373394],"study_design_scores_gemma":[0.0007444977,0.00042169302,0.000033997883,0.0029506485,0.0000712158,0.00000635432,0.0014512445,0.00018475065,0.0043209996,0.0002792286,0.98913765,0.0003977194],"about_ca_topic_score_codex":0.000005501833,"about_ca_topic_score_gemma":0.000072018585,"teacher_disagreement_score":0.9933362,"about_ca_system_score_codex":0.000034167737,"about_ca_system_score_gemma":0.000076648925,"threshold_uncertainty_score":0.4892609},"labels":[],"label_agreement":null},{"id":"W3132567065","doi":"10.3390/pr9020360","title":"Multi-Objective Optimizations of Non-Isothermal Simulated Moving Bed Reactor: Parametric Analyses","year":2021,"lang":"en","type":"article","venue":"Processes","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Isothermal process; Sorting; Plug flow; Multi-objective optimization; Thermodynamics; Parametric statistics; Throughput; Chemistry; Mathematical optimization; Materials science; Process engineering; Computer science; Mathematics; Algorithm; Engineering; Physics; Statistics","score_opus":0.03432335276830886,"score_gpt":0.33597285513981257,"score_spread":0.3016495023715037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3132567065","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92053324,0.0075481366,0.07041993,0.00007357029,0.00004612923,0.00027404033,0.00006704609,0.000029920944,0.0010079861],"genre_scores_gemma":[0.9901454,0.0004266877,0.009069915,0.000041216415,0.000021130463,0.000014598932,0.0001274737,0.000011334368,0.00014223343],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992771,0.000046285128,0.00020147323,0.00027251025,0.000088190085,0.000114400085],"domain_scores_gemma":[0.99885416,0.00004030297,0.00011275175,0.00026501445,0.000685448,0.000042297703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000075212134,0.000093617506,0.00013514994,0.000053283526,0.00004851394,0.0000165223,0.00010748793,0.00008876941,0.000042444066],"category_scores_gemma":[0.0018347737,0.00008969534,0.00005215959,0.0006171211,0.000054846103,0.0000068119225,0.00004782235,0.000049763483,0.0000020756547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045122026,0.0004398169,0.011542984,0.00028759093,0.000117811076,0.0000014806861,0.00017108642,0.00923093,0.9769615,0.0000035452942,0.000016824444,0.001181301],"study_design_scores_gemma":[0.00033918594,0.00004109989,0.005186151,0.000012074811,0.000027951228,0.0000018822758,0.00014473905,0.0038657838,0.98961174,0.000018474055,0.00063251366,0.000118426266],"about_ca_topic_score_codex":0.000023532953,"about_ca_topic_score_gemma":0.000027015283,"teacher_disagreement_score":0.069612175,"about_ca_system_score_codex":0.000008985259,"about_ca_system_score_gemma":0.00028885138,"threshold_uncertainty_score":0.365767},"labels":[],"label_agreement":null},{"id":"W3133477296","doi":"10.1016/j.bpj.2020.11.1964","title":"Diffusion NMR and Rheology Study of a Model Polymer and a Disordered Protein in the Presence of Bacterial Cell Lysate Crowders","year":2021,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Macromolecular crowding; Lysis; Chemistry; Polymer; Macromolecule; Ficoll; Biomolecule; Rheology; Diffusion; Intrinsically disordered proteins; Biophysics; Chemical physics; Thermodynamics; Biochemistry; Organic chemistry; Physics","score_opus":0.011088084559315856,"score_gpt":0.24458938030207267,"score_spread":0.2335012957427568,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133477296","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99923235,0.00016755988,0.00022969632,0.00015300693,0.000010651504,0.00018420142,0.0000055660103,6.461803e-7,0.000016324391],"genre_scores_gemma":[0.9997555,0.000064200365,0.00008718864,0.000014268053,0.000023828428,0.000010024765,0.0000026996022,0.0000032115324,0.000039060116],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928474,0.0002184166,0.00018233781,0.00014299789,0.000089193,0.00008232802],"domain_scores_gemma":[0.9996662,0.000012331887,0.00008820415,0.00015190103,0.00004975957,0.00003160119],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013448072,0.00006215736,0.00011790427,0.0000143102725,0.000036049652,0.000011371883,0.000088614266,0.00004796223,0.000004075609],"category_scores_gemma":[0.000049635255,0.00004302112,0.000028105975,0.00005099578,0.00012089846,0.0000037465595,0.00008253941,0.000086819186,4.9616236e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001929405,0.0007107157,0.002430329,0.000015346724,0.00000802452,0.0000017734819,0.0006281638,0.0000026472128,0.9953367,0.00007539518,0.0000019625486,0.0005959832],"study_design_scores_gemma":[0.0023945651,0.0008230163,0.04937919,0.000014663019,0.000018719886,0.000018520359,0.0021745744,0.0024347177,0.94234693,0.00026145458,0.000019801111,0.00011386632],"about_ca_topic_score_codex":0.000013491088,"about_ca_topic_score_gemma":0.00002026297,"teacher_disagreement_score":0.052989807,"about_ca_system_score_codex":0.0000017748824,"about_ca_system_score_gemma":0.000045237444,"threshold_uncertainty_score":0.17543504},"labels":[],"label_agreement":null},{"id":"W3133777094","doi":"10.1038/s41598-021-84946-8","title":"Global multi-method analysis of interaction parameters for reversibly self-associating macromolecules at high concentrations","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institutes of Health","keywords":"Macromolecule; Virial coefficient; Chemical physics; Colloid; Diffusion; Sedimentation; Colloidal particle; Analytical Ultracentrifugation; Chemistry; Dynamic light scattering; Biological system; Statistical physics; Materials science; Physics; Nanotechnology; Thermodynamics; Chromatography; Physical chemistry; Nanoparticle; Ultracentrifuge; Biology; Biochemistry","score_opus":0.01618402245260802,"score_gpt":0.3139235100989688,"score_spread":0.29773948764636077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133777094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9358443,0.0001628723,0.062468573,0.000092704504,0.00097433885,0.00023820192,0.00009848117,0.000013531259,0.00010698184],"genre_scores_gemma":[0.9140621,0.000004896951,0.08439649,0.000028450268,0.000010099623,0.000026270369,0.0010419759,0.0000036967376,0.00042602315],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99860984,0.00011904917,0.00039958666,0.0005660442,0.0001592835,0.00014619622],"domain_scores_gemma":[0.9985184,0.000028988126,0.0003935174,0.00052324455,0.00048036283,0.000055475437],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082386524,0.00007804267,0.00016398932,0.00004141288,0.00018775975,0.00005811713,0.00006475967,0.00007972382,0.000021086124],"category_scores_gemma":[0.00073300954,0.00008272439,0.00023345253,0.0005615607,0.000057142304,0.0000066477505,0.00006038952,0.000024677827,5.644572e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024060695,0.00023295608,0.09955832,0.000030134825,0.0007271443,0.00001026739,0.00013617317,0.0012360947,0.89575243,0.00013116792,0.000827343,0.0013338974],"study_design_scores_gemma":[0.00027144875,0.000032062526,0.02733922,0.000007520876,0.00046789923,0.000024028343,0.0002640602,0.0037171089,0.95853364,0.0003770601,0.008799247,0.0001667044],"about_ca_topic_score_codex":0.00003785443,"about_ca_topic_score_gemma":0.00037679117,"teacher_disagreement_score":0.0722191,"about_ca_system_score_codex":0.0000994721,"about_ca_system_score_gemma":0.00016046166,"threshold_uncertainty_score":0.3373403},"labels":[],"label_agreement":null},{"id":"W3134302097","doi":"10.1101/2021.03.08.434487","title":"Boundary convection during velocity sedimentation in the Optima analytical ultracentrifuge","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Sudbury","funders":"","keywords":"Analytical Ultracentrifugation; Ultracentrifuge; Chemistry; Convection; Local optimum; Chromatography; Biopharmaceutical; Sedimentation; Thermodynamics; Mathematics; Physics; Mathematical optimization","score_opus":0.011049348589855464,"score_gpt":0.2390663314268249,"score_spread":0.22801698283696945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3134302097","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954018,0.001525611,0.0015223701,0.00040434196,0.0003832607,0.00064741797,0.00005989639,0.0000422827,0.000013019826],"genre_scores_gemma":[0.99797654,0.00033211615,0.0009791579,0.00021121248,0.0002642025,0.00019206526,0.0000069320786,0.000032771055,0.0000049917517],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977599,0.0003672649,0.00042884445,0.0008235409,0.0002949441,0.0003255229],"domain_scores_gemma":[0.99840325,0.000020369349,0.00020199268,0.0010042845,0.00027170507,0.00009841445],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008196359,0.00029202248,0.0002530289,0.00008221243,0.00016779422,0.00023351885,0.0003663926,0.00046242567,0.000033543565],"category_scores_gemma":[0.0003034965,0.00028434384,0.000139478,0.0002906333,0.0001379389,0.0000135361815,0.00018827445,0.00056587806,0.0000073210817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008149486,0.000280607,0.014220876,0.00020472165,0.000082860664,0.00002295065,0.000029783332,0.000114092865,0.9847941,0.00011589762,0.00004853819,0.000004081821],"study_design_scores_gemma":[0.00052143604,0.000030896907,0.47542378,0.000053424334,0.00003903582,7.2519626e-8,0.0000275819,0.0004190664,0.52097225,9.837336e-7,0.0021630565,0.00034841037],"about_ca_topic_score_codex":0.000035237525,"about_ca_topic_score_gemma":0.000007224708,"teacher_disagreement_score":0.46382183,"about_ca_system_score_codex":0.0001704664,"about_ca_system_score_gemma":0.0005015084,"threshold_uncertainty_score":0.9999609},"labels":[],"label_agreement":null},{"id":"W3135106422","doi":"10.1016/j.jpba.2021.114013","title":"PAT solutions to monitor adsorption of Tetanus Toxoid with aluminum adjuvants","year":2021,"lang":"en","type":"article","venue":"Journal of Pharmaceutical and Biomedical Analysis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Autodesk (Canada); Sanofi (Canada)","funders":"","keywords":"Chemistry; Adsorption; Toxoid; Aluminium; Particle size; Particle (ecology); Kinetics; Chromatography; Antigen; Organic chemistry; Physical chemistry; Immunization","score_opus":0.021929282888243265,"score_gpt":0.3129601036399652,"score_spread":0.29103082075172193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135106422","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96588737,0.002935357,0.02764901,0.0032979718,0.000074358606,0.000061472056,0.0000448058,0.0000024548751,0.00004717685],"genre_scores_gemma":[0.99700594,0.0005213072,0.0019983067,0.00020527284,0.00015455321,0.000002427889,0.000021430775,0.0000036112444,0.00008714124],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99884415,0.00010737406,0.00039379334,0.00017802046,0.0003200781,0.00015660658],"domain_scores_gemma":[0.9989625,0.000022801862,0.00013089235,0.00013722459,0.000375317,0.00037127078],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038692806,0.00008802108,0.00026573273,0.000114107024,0.000040751085,0.000012286979,0.00010008297,0.00008478999,0.00014535274],"category_scores_gemma":[0.00018125393,0.000059420094,0.00017449602,0.0005788094,0.00018276961,0.0000058853525,0.00006543254,0.0001191984,0.0000015024319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002999119,0.00048469452,0.0051181167,0.00002970104,0.0009001062,0.000016427808,0.000033051525,0.000013130987,0.957629,0.000028296763,0.00022666459,0.035220888],"study_design_scores_gemma":[0.002164844,0.001322514,0.057364933,0.000054750377,0.0026321777,0.00020296343,0.00038830983,0.0010733342,0.84895825,0.00014126224,0.08536437,0.00033230122],"about_ca_topic_score_codex":0.0000036768101,"about_ca_topic_score_gemma":0.0000093675735,"teacher_disagreement_score":0.10867077,"about_ca_system_score_codex":0.000011806855,"about_ca_system_score_gemma":0.000081901904,"threshold_uncertainty_score":0.24230811},"labels":[],"label_agreement":null},{"id":"W3151883212","doi":"10.1016/j.csbj.2021.03.030","title":"In-line monitoring of surfactant clearance in viral vaccine downstream processing","year":2021,"lang":"en","type":"article","venue":"Computational and Structural Biotechnology Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada); Queen's University","funders":"","keywords":"Pulmonary surfactant; Univariate; Cross-flow filtration; Filtration (mathematics); Chromatography; Multivariate statistics; Materials science; Downstream processing; Chemistry; Membrane; Mathematics; Statistics","score_opus":0.008192866058944641,"score_gpt":0.26642927487361856,"score_spread":0.2582364088146739,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3151883212","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930766,0.0041723982,0.0010415005,0.0015801952,0.000071599,0.000041781106,0.000004676928,0.0000036495592,0.0000075784706],"genre_scores_gemma":[0.9940626,0.00029490807,0.00554829,0.000029989003,0.000041926975,0.0000011294599,0.000009343863,0.0000033121678,0.0000085196725],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999322,0.00003720896,0.00028083796,0.00017159186,0.00007255919,0.00011580731],"domain_scores_gemma":[0.999696,0.00000797193,0.00009611779,0.0000688217,0.00010423357,0.000026842608],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000111865,0.00007574398,0.00012949451,0.00007120405,0.000049884886,0.000012346617,0.0000781238,0.00013896458,0.0000066481716],"category_scores_gemma":[0.000074256444,0.000067366105,0.000024565968,0.00013628369,0.000070571296,0.000010436406,0.000046704863,0.0002181882,1.7409067e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036808927,0.00007723382,0.27549118,0.00006574321,0.000027654203,0.00006304012,0.00010890675,0.0073894314,0.5876048,0.000871229,0.00000797192,0.12792471],"study_design_scores_gemma":[0.0011476016,0.00011429337,0.7159517,0.000049578408,0.0000031723202,0.00061735784,0.00016266611,0.0033588184,0.26602268,0.012275106,0.00016655744,0.00013049174],"about_ca_topic_score_codex":0.0000032877433,"about_ca_topic_score_gemma":0.000007422578,"teacher_disagreement_score":0.4404605,"about_ca_system_score_codex":0.000015179015,"about_ca_system_score_gemma":0.000086229105,"threshold_uncertainty_score":0.274711},"labels":[],"label_agreement":null},{"id":"W3155486577","doi":"10.1016/j.chroma.2021.462167","title":"A cuboid chromatography device having short bed-height gives better protein separation at a significantly lower pressure drop than a taller column having the same bed-volume","year":2021,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cuboid; Pressure drop; Chemistry; Packed bed; Chromatography; Drop (telecommunication); Volume (thermodynamics); Mechanics; Analytical Chemistry (journal); Geometry; Mathematics; Thermodynamics","score_opus":0.009927682889716582,"score_gpt":0.2517268759382924,"score_spread":0.24179919304857583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3155486577","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9840519,0.010651494,0.0020972625,0.0016359813,0.0002089017,0.00079801335,0.000058203834,0.000028464867,0.00046980887],"genre_scores_gemma":[0.99635905,0.0002700492,0.0021020314,0.00045101592,0.00037182358,0.00011131125,0.000058758927,0.00004639769,0.0002295758],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99689853,0.0005369276,0.0008792491,0.0005420081,0.000667492,0.0004757776],"domain_scores_gemma":[0.99760014,0.000042035306,0.00057396124,0.00079293863,0.00074592704,0.0002449862],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00097458216,0.00035219188,0.00045098024,0.00018706072,0.0005259834,0.00025484158,0.00054486963,0.00034796566,0.00018833642],"category_scores_gemma":[0.0001854831,0.0002891246,0.0008175297,0.0005856554,0.0003572007,0.000059736554,0.0001730692,0.000441581,0.0000052331998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023633361,0.0004303638,0.044878487,0.000121665755,0.0007035392,0.00006523933,0.0006679352,0.000013151643,0.9495733,0.00006533357,0.0026236735,0.00062101096],"study_design_scores_gemma":[0.0015530788,0.000813002,0.09011113,0.00044822117,0.00047242318,0.00064200285,0.00095501187,0.00017174106,0.6058608,0.00045424246,0.29755452,0.00096381345],"about_ca_topic_score_codex":0.000024955936,"about_ca_topic_score_gemma":0.00028519405,"teacher_disagreement_score":0.34371245,"about_ca_system_score_codex":0.000035383346,"about_ca_system_score_gemma":0.00035184357,"threshold_uncertainty_score":0.9999561},"labels":[],"label_agreement":null},{"id":"W3158784427","doi":"10.1016/j.jpba.2021.114094","title":"Multi-attribute method based characterization of antibody drug conjugates (ADC) at the intact and subunit levels","year":2021,"lang":"en","type":"article","venue":"Journal of Pharmaceutical and Biomedical Analysis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"SCIEX","keywords":"Chemistry; Antibody-drug conjugate; Biopharmaceutical; Critical quality attributes; Workflow; Drug discovery; Conjugate; Chromatography; Computational biology; Computer science; Antibody; Biochemistry; Monoclonal antibody; Database; Biotechnology","score_opus":0.030125666504035552,"score_gpt":0.36958733023117724,"score_spread":0.3394616637271417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3158784427","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92171735,0.0017023584,0.069949806,0.006416327,0.00003821557,0.000055233453,0.00011566187,0.0000016886481,0.0000033399162],"genre_scores_gemma":[0.99628776,0.00095067476,0.0018697844,0.0005459262,0.00006113079,0.0000012773442,0.00017111824,0.0000038080111,0.00010849581],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986781,0.00036402748,0.00043715493,0.00017802118,0.00022514607,0.00011757463],"domain_scores_gemma":[0.99906737,0.00009845534,0.0002192075,0.00012834377,0.00029005093,0.00019656176],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010392556,0.00009640059,0.00028363973,0.00007520337,0.00007870712,0.000020944984,0.00009938344,0.00008229182,0.00023520207],"category_scores_gemma":[0.00027300278,0.000058084563,0.00017486452,0.00038583652,0.0002918192,0.000007160257,0.000094907075,0.00013751838,4.6783063e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007750192,0.00018440034,0.018582692,0.00003850041,0.0005016481,0.000006355541,0.000027308683,0.0000020872646,0.9747749,0.000008499042,0.000016005244,0.0057801036],"study_design_scores_gemma":[0.0011120153,0.00008815111,0.113677815,0.000015025097,0.00094878394,0.00003963191,0.000060224655,0.0065939506,0.8541286,0.00001646474,0.023209898,0.00010944307],"about_ca_topic_score_codex":0.0000041749176,"about_ca_topic_score_gemma":0.0000054878305,"teacher_disagreement_score":0.1206463,"about_ca_system_score_codex":0.000008688437,"about_ca_system_score_gemma":0.0000756398,"threshold_uncertainty_score":0.25752977},"labels":[],"label_agreement":null},{"id":"W3174051643","doi":"10.1021/acs.analchem.0c04625","title":"Reference Protocol to Assess Analytical Performance of Higher Order Structural Analysis Measurements: Results from an Interlaboratory Comparison","year":2021,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Directorate for Biological Sciences; Department for Business, Energy and Industrial Strategy, UK Government","keywords":"Comparability; Chemistry; Protocol (science); Standardization; Benchmark (surveying); Biochemical engineering; Data mining; Computer science; Mathematics","score_opus":0.08035332798564535,"score_gpt":0.3856396491193985,"score_spread":0.3052863211337532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174051643","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934686,0.000027512311,0.0005601784,0.00020753728,0.000020284424,0.0014983243,0.00020579655,0.000016678017,0.003995135],"genre_scores_gemma":[0.99620104,0.0000010688047,0.0012930193,0.00015562096,0.000086983746,0.00068782456,0.0008926269,0.000011580897,0.00067025144],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99781847,0.000113246686,0.0006707037,0.0007517504,0.0003974954,0.000248328],"domain_scores_gemma":[0.99750996,0.000024413215,0.00015490601,0.0010575369,0.00097478053,0.00027838896],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028733804,0.00020699276,0.00039947114,0.000030867923,0.00005294197,0.000044148503,0.00035482398,0.00023153762,0.0005911854],"category_scores_gemma":[0.0005367092,0.00019244594,0.00011999863,0.0007285166,0.00013402922,0.000012518041,0.00014403381,0.00020260083,0.000006827973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018676419,0.00069107,0.21347697,0.00015967293,0.0013408419,0.000005577487,0.00006485,0.0007858827,0.7792104,0.0000697846,0.0008003822,0.001526927],"study_design_scores_gemma":[0.0009609008,0.0001471443,0.10649689,0.00002186128,0.00031474754,7.908561e-7,0.00008497792,0.01091809,0.8695806,0.000018673356,0.0110837575,0.0003715584],"about_ca_topic_score_codex":0.000028853194,"about_ca_topic_score_gemma":0.000036737434,"teacher_disagreement_score":0.10698008,"about_ca_system_score_codex":0.000047780322,"about_ca_system_score_gemma":0.00024179714,"threshold_uncertainty_score":0.78477174},"labels":[],"label_agreement":null},{"id":"W3174073138","doi":"10.1016/j.chroma.2021.462375","title":"Fast and high-resolution purification of a PEGylated protein using a z2 laterally-fed membrane chromatography device","year":2021,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; McMaster University; Bristol-Myers Squibb","keywords":"Chemistry; Chromatography; PEGylation; Resolution (logic); Membrane; Ion exchange; High resolution; Volumetric flow rate; Protein purification; Analytical Chemistry (journal); Ion; Polyethylene glycol; Biochemistry","score_opus":0.011660857446478589,"score_gpt":0.24316166920291918,"score_spread":0.23150081175644058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174073138","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99030167,0.0047242683,0.004390094,0.00018808438,0.000059903665,0.00024534782,0.000020169531,0.000008818754,0.00006166836],"genre_scores_gemma":[0.9886181,0.00031297468,0.010903813,0.00003890169,0.0000626142,0.000008337091,0.000030835123,0.000015807176,0.000008618995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998433,0.00021546951,0.0006682328,0.0002489435,0.00025767946,0.000176685],"domain_scores_gemma":[0.99826413,0.000010761369,0.0006595635,0.0003190934,0.0006299406,0.00011651038],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041561705,0.00016351968,0.00031074003,0.00021609424,0.000085239495,0.000039158862,0.00014942272,0.00017284871,0.000022022334],"category_scores_gemma":[0.00008813802,0.00015316281,0.00024409918,0.0005353252,0.00015253718,0.000025185165,0.00004263811,0.00013455925,3.3224424e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018438915,0.00020119177,0.003174825,0.00016332067,0.00018156214,0.000008151993,0.000095763324,0.000032566317,0.9948991,0.0001751244,0.000014469308,0.00086952426],"study_design_scores_gemma":[0.0013774039,0.00032989713,0.037664175,0.00018757922,0.0000873946,0.00032084825,0.00012934729,0.00032390316,0.9578464,0.00030962826,0.0012180356,0.00020540302],"about_ca_topic_score_codex":0.000024206582,"about_ca_topic_score_gemma":0.000013910039,"teacher_disagreement_score":0.03705273,"about_ca_system_score_codex":0.000011130504,"about_ca_system_score_gemma":0.00017394367,"threshold_uncertainty_score":0.6245798},"labels":[],"label_agreement":null},{"id":"W3175258892","doi":"10.1096/fasebj.26.1_supplement.1034.16","title":"Porcine milk fat globule membrane proteins that bind to F4ac fimbria of Escherichia coli","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Institute for Biological Sciences; University of Saskatchewan; National Research Council Canada; Western University","funders":"","keywords":"Enterotoxigenic Escherichia coli; Biology; Fimbria; Biochemistry; Escherichia coli; Microbiology; Enterotoxin","score_opus":0.020824778605061742,"score_gpt":0.2570451103147896,"score_spread":0.23622033170972787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175258892","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932997,0.0015918723,0.0025155146,0.0011171554,0.00019360246,0.00038644334,0.000027900052,0.0000057334883,0.0008620684],"genre_scores_gemma":[0.9969327,0.00009757786,0.0014914316,0.00035268985,0.00037877134,0.000017773957,0.000012791839,0.000012750784,0.00070350524],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990035,0.00015517934,0.00023719207,0.00012974463,0.00020076787,0.00027358357],"domain_scores_gemma":[0.99911773,0.000010542395,0.00015884615,0.00040350918,0.000104185965,0.00020518435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007402836,0.00012128532,0.0001455183,0.000027017995,0.00013597096,0.000021711332,0.0003057752,0.00008376428,0.00019058531],"category_scores_gemma":[0.00014015815,0.00008180804,0.00010009342,0.00010644158,0.00007791096,0.000007816016,0.0000821696,0.00015604236,0.00002230169],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001591677,0.00010420199,0.0056258133,0.00001159528,0.000038074457,5.58538e-7,0.00014137232,0.00001229829,0.99239796,0.000068515714,0.0007485024,0.0006919548],"study_design_scores_gemma":[0.0003824463,0.00015324344,0.014379362,0.000011262057,0.000018517087,0.000034193483,0.00013081502,0.0000075327825,0.9686956,0.0000455958,0.016035168,0.00010626222],"about_ca_topic_score_codex":0.000020161302,"about_ca_topic_score_gemma":0.000009575567,"teacher_disagreement_score":0.023702342,"about_ca_system_score_codex":0.000018320088,"about_ca_system_score_gemma":0.00006336946,"threshold_uncertainty_score":0.3336035},"labels":[],"label_agreement":null},{"id":"W3183198452","doi":"10.1016/j.chroma.2021.462412","title":"Patterns of protein adsorption in ion-exchange particles and columns: Evolution of protein concentration profiles during load, hold, and wash steps predicted for pore and solid diffusion mechanisms","year":2021,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Diffusion; Adsorption; Chromatography; Ion exchange; Phase (matter); Molecular diffusion; Ion; Analytical Chemistry (journal); Chemical physics; Chemical engineering; Thermodynamics; Physical chemistry; Organic chemistry","score_opus":0.006373720031758766,"score_gpt":0.2222576637347832,"score_spread":0.21588394370302444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3183198452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925001,0.0033081123,0.0032325073,0.00008801558,0.000016454058,0.0007878511,0.000062387444,0.000002783678,0.0000017539907],"genre_scores_gemma":[0.9983789,0.00046404195,0.0010366737,0.0000036901743,0.000024512332,0.00006140193,0.00002010666,0.0000066172206,0.000004054718],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999063,0.00009800984,0.00042210493,0.00016072624,0.00015202562,0.00010412684],"domain_scores_gemma":[0.99913186,0.0000067335995,0.00040466254,0.00009943504,0.00030219223,0.000055115288],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000316959,0.00008668371,0.0001924786,0.00006039154,0.000031412037,0.000014667377,0.000038059934,0.00010430434,0.0000027068672],"category_scores_gemma":[0.00009944983,0.000081133825,0.00005406428,0.00009656895,0.00006556648,0.000023110126,0.000032546544,0.000055670516,5.8037957e-9],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029730238,0.00014945798,0.033739273,0.0006242228,0.000028874541,0.0000012866757,0.00019462216,0.0000011809101,0.9640779,0.00016664203,0.000001032321,0.0007181904],"study_design_scores_gemma":[0.0017506889,0.00043705088,0.19995697,0.0003332009,0.000018266423,0.00002874826,0.000388407,0.00023523427,0.79592746,0.000842403,0.000013727292,0.000067806744],"about_ca_topic_score_codex":0.0000117779655,"about_ca_topic_score_gemma":0.00004695043,"teacher_disagreement_score":0.16815042,"about_ca_system_score_codex":0.000015261656,"about_ca_system_score_gemma":0.000081242295,"threshold_uncertainty_score":0.33085415},"labels":[],"label_agreement":null},{"id":"W3184952372","doi":"10.1016/j.ab.2021.114306","title":"Boundary convection during sedimentation velocity in the Optima analytical ultracentrifuge","year":2021,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Sudbury","funders":"","keywords":"Ultracentrifuge; Analytical Ultracentrifugation; Chemistry; Local optimum; Convection; Sedimentation; Sedimentation coefficient; Chromatography; Thermodynamics; Mathematics; Physics; Mathematical optimization; Biochemistry; Biology","score_opus":0.010410637547017017,"score_gpt":0.27538040804211755,"score_spread":0.2649697704951005,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3184952372","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99443847,0.0005582666,0.00043562363,0.001778622,0.000043801556,0.00011329425,0.000017265382,0.0000125044535,0.0026021549],"genre_scores_gemma":[0.9980823,0.00008148901,0.00017558677,0.0004197093,0.00014651312,0.00001942612,0.00031653253,0.000007978855,0.00075045583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986602,0.00011016911,0.0002883278,0.0004610576,0.00023085752,0.00024936796],"domain_scores_gemma":[0.99924725,0.000030912648,0.000050599116,0.00046583646,0.00011663527,0.00008875556],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033381738,0.00013738255,0.00013102115,0.000019551471,0.00011474973,0.00006712602,0.00017444177,0.0001924486,0.00013769942],"category_scores_gemma":[0.00045545166,0.0001201914,0.00011790626,0.00027696503,0.0001708563,0.0000064018036,0.000053376953,0.0002201358,0.000014880992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019431472,0.0006043362,0.017462365,0.000107032734,0.000091992966,0.000056277186,0.00008400392,0.000036324942,0.97861755,0.0006060393,0.00086640083,0.0012733382],"study_design_scores_gemma":[0.0007300873,0.000032410186,0.04425535,0.000011312176,0.00003549043,0.00007402559,0.00042494724,0.0013365129,0.94769293,0.00011901827,0.0050705103,0.00021742102],"about_ca_topic_score_codex":0.000007919166,"about_ca_topic_score_gemma":0.0000054561715,"teacher_disagreement_score":0.030924661,"about_ca_system_score_codex":0.00006317614,"about_ca_system_score_gemma":0.00017565912,"threshold_uncertainty_score":0.49012628},"labels":[],"label_agreement":null},{"id":"W3203253787","doi":"10.1007/s00216-021-03648-2","title":"Monitoring process-related impurities in biologics–host cell protein analysis","year":2021,"lang":"en","type":"article","venue":"Analytical and Bioanalytical Chemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alpha Technologies (Canada)","funders":"","keywords":"Documentation; Chemistry; Biochemical engineering; Process development; Chromatography; Process (computing); Computer science; Nanotechnology; Process engineering; Computational biology; Materials science; Engineering; Biology","score_opus":0.008946213862475934,"score_gpt":0.2574895487463712,"score_spread":0.24854333488389527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203253787","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99108505,0.0025904723,0.000117741125,0.00073440286,0.000012816924,0.000105949395,0.00002314752,0.000020845519,0.005309593],"genre_scores_gemma":[0.9956903,0.00024992385,0.00013602879,0.00006266157,0.00006629224,0.000023352091,0.00007507514,0.000010311608,0.0036860644],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981559,0.00006169539,0.00046576362,0.0007491774,0.00019099873,0.0003764607],"domain_scores_gemma":[0.99909973,0.000029296694,0.00006614716,0.00040318872,0.00016911684,0.00023250544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026480516,0.00022967446,0.0003661297,0.000052911968,0.00007149805,0.000060722272,0.00017193488,0.00035978146,0.00017932562],"category_scores_gemma":[0.00023410004,0.0002025231,0.00021707408,0.000826108,0.0002978716,0.0000073054575,0.00013509145,0.00027010706,0.0000062118843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013742447,0.0008550118,0.33623603,0.0003689908,0.0006975264,0.00010059847,0.000048592672,0.000035915695,0.65943545,0.00045373148,0.000024587196,0.0016061476],"study_design_scores_gemma":[0.00059666164,0.00005912137,0.022608811,0.00002916394,0.0002981037,0.00001398171,0.00045530644,0.002279209,0.97136724,0.0007958165,0.0010258831,0.0004707227],"about_ca_topic_score_codex":0.000010883695,"about_ca_topic_score_gemma":0.0000073475026,"teacher_disagreement_score":0.3136272,"about_ca_system_score_codex":0.000024880961,"about_ca_system_score_gemma":0.00012059536,"threshold_uncertainty_score":0.8258652},"labels":[],"label_agreement":null},{"id":"W328270376","doi":"10.1023/a:1019814713428","title":"Characterization of Asparagine Deamidation and Aspartate Isomerization in Recombinant Human Interleukin-11","year":2002,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Deamidation; Recombinant DNA; Asparagine; Chemistry; Biochemistry; Isomerization; Aspartic acid; Stereochemistry; Amino acid; Enzyme","score_opus":0.1556430596101426,"score_gpt":0.43140086898556507,"score_spread":0.2757578093754225,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W328270376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99719656,0.00018696972,0.00071746757,0.0010215773,0.000030332145,0.00031570767,0.0000049965647,0.0000054701254,0.00052093534],"genre_scores_gemma":[0.99884987,0.00042774994,0.00004391539,0.000043113985,0.000025083933,0.00004735526,0.00009663736,0.000008387686,0.00045787782],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998834,0.00027360418,0.00023871631,0.0002493304,0.00018919678,0.00021515934],"domain_scores_gemma":[0.9995423,0.000022445005,0.00003897279,0.0001685194,0.00014424972,0.00008351564],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008792499,0.00006638074,0.00009223632,0.00011082875,0.00006279873,0.000018119441,0.0000996174,0.000067648034,0.00014146039],"category_scores_gemma":[0.00026200424,0.00006617919,0.000016836755,0.00021901267,0.0001488681,0.000010796899,0.00007359139,0.0001351642,0.000006508194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045138306,0.00017342107,0.008610844,0.00004031695,0.0000043529503,6.048676e-7,0.00008529793,0.0000012558723,0.981638,0.0009579882,0.00002389805,0.008418843],"study_design_scores_gemma":[0.00073745195,0.0001625513,0.053542975,0.000019939034,0.0000028856557,0.0000021559827,0.000020694208,0.0050815353,0.9243287,0.0003417589,0.015660267,0.00009908483],"about_ca_topic_score_codex":0.000011596877,"about_ca_topic_score_gemma":0.000018858542,"teacher_disagreement_score":0.05730934,"about_ca_system_score_codex":0.000020315145,"about_ca_system_score_gemma":0.000014396951,"threshold_uncertainty_score":0.26987094},"labels":[],"label_agreement":null},{"id":"W36981869","doi":"10.3390/ijerph20064963","title":"Bio-pharmaceuticals : emerging proniosomes in drug delivery","year":2011,"lang":"en","type":"book-chapter","venue":"Nova Science Publishers eBooks","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Niosome; Drug delivery; Nanotechnology; Liposome; Drug; Amphiphile; Materials science; Chemistry; Pharmacology; Medicine; Membrane; Vesicle; Polymer; Organic chemistry","score_opus":0.048841828546021586,"score_gpt":0.2940008489275362,"score_spread":0.2451590203815146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W36981869","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012368563,0.00097275,0.000049259288,0.0002870025,0.00052981084,0.00070279354,0.000017346929,0.00003910961,0.9850334],"genre_scores_gemma":[0.6680507,0.000051682648,0.0005517106,0.0006680615,0.00017288268,0.00006761921,0.00004892125,0.0000571162,0.3303313],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99735665,0.00003129112,0.00045831213,0.0010705217,0.0004844303,0.00059877144],"domain_scores_gemma":[0.9983291,0.000010203289,0.00019946857,0.00085657235,0.00034369706,0.00026098383],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015890666,0.0003263372,0.00026034782,0.00035792534,0.00014903292,0.00027337697,0.0010996395,0.00030206755,0.00035861394],"category_scores_gemma":[0.00015571866,0.00031642467,0.00012598692,0.00008876841,0.0013196412,0.000045469293,0.00039765146,0.00040479854,0.00003733151],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036223474,0.00027699486,0.0024089601,0.0003123252,0.0001635424,0.000045987614,0.0017975523,0.000003823166,0.24410313,0.07906633,0.019461157,0.651998],"study_design_scores_gemma":[0.00042928357,0.000058565296,0.0004550766,0.00005637645,0.000017926262,0.000008259605,0.000064815446,0.0000130115395,0.059365433,0.007149097,0.9316853,0.00069680705],"about_ca_topic_score_codex":0.000064982894,"about_ca_topic_score_gemma":0.0001345823,"teacher_disagreement_score":0.9122242,"about_ca_system_score_codex":0.00011740425,"about_ca_system_score_gemma":0.0010436076,"threshold_uncertainty_score":0.9999288},"labels":[],"label_agreement":null},{"id":"W4200196821","doi":"10.1101/2021.12.12.472287","title":"REVOLVER: a low-cost automated protein purifier based on parallel preparative gravity column workflows","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Scalability; Workflow; Computer science; Process (computing); Automation; Protein purification; Table (database); Chromatography; Chemistry; Engineering; Database; Operating system","score_opus":0.011494266032237981,"score_gpt":0.2393772066131981,"score_spread":0.22788294058096012,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200196821","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.980392,0.0012616154,0.010671,0.000389776,0.0005883685,0.0052930075,0.0006805615,0.0006497029,0.00007401239],"genre_scores_gemma":[0.9854305,0.000077727,0.010761081,0.00043485285,0.00024969212,0.0028499311,0.000025104679,0.00012112325,0.00004998846],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99536234,0.0006711193,0.0007435971,0.0020456328,0.0005103877,0.0006669025],"domain_scores_gemma":[0.99505717,0.000028504392,0.0005561891,0.0030470274,0.0009246309,0.00038647276],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000901568,0.0007657357,0.0007017335,0.0001320933,0.0002440881,0.00029790998,0.0007465427,0.001174941,0.000094212075],"category_scores_gemma":[0.0007583299,0.00085278,0.00036353094,0.00044043636,0.0002294694,0.000014721241,0.00044725114,0.00083527877,0.000047103935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005376733,0.0010912869,0.002691126,0.0005641621,0.00023251474,0.00005206677,0.000011722842,0.0016331086,0.9916552,0.00009726169,0.0014254757,0.000008453595],"study_design_scores_gemma":[0.0017502402,0.00024267666,0.052616023,0.00087748544,0.00009968846,2.7611913e-8,0.0000058711084,0.012377366,0.9092399,0.0000036729773,0.020949159,0.0018378716],"about_ca_topic_score_codex":0.000040813375,"about_ca_topic_score_gemma":0.000019141475,"teacher_disagreement_score":0.08241523,"about_ca_system_score_codex":0.00024570432,"about_ca_system_score_gemma":0.0017558378,"threshold_uncertainty_score":0.9993923},"labels":[],"label_agreement":null},{"id":"W4200538481","doi":"10.21203/rs.3.rs-1184379/v1","title":"Multi-Wavelength Analytical Ultracentrifugation of Biopolymer Mixtures and Interactions","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of Lethbridge","funders":"National Institutes of Health; University of Alberta; University of Montana; National Science Foundation","keywords":"Biopolymer; Analytical Ultracentrifugation; Wavelength; Ultracentrifuge; Polymer science; Chromatography; Chemistry; Nanotechnology; Materials science; Polymer; Optoelectronics; Organic chemistry","score_opus":0.06405244413088769,"score_gpt":0.4108550609785474,"score_spread":0.34680261684765973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200538481","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98832124,0.0066599483,0.0028563468,0.0007255518,0.00012203007,0.00066237856,0.00018501087,0.000011131637,0.00045637612],"genre_scores_gemma":[0.9959402,0.0014636195,0.001313,0.000012680441,0.00009464632,0.000065454944,0.0006388685,0.000013243052,0.00045826135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982482,0.00043030252,0.0002690709,0.00051959854,0.0003123723,0.00022045006],"domain_scores_gemma":[0.99843276,0.00006333187,0.00007882295,0.00060373166,0.00070032786,0.00012104221],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006210426,0.00012850833,0.00018287965,0.00012252737,0.00008856417,0.00006204067,0.00016491482,0.00028322818,0.000106137435],"category_scores_gemma":[0.001124648,0.00012333208,0.00011263196,0.00013826664,0.00027468463,0.0000036240351,0.00043093655,0.0005574098,0.0000025277284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023265685,0.0010466235,0.015694551,0.0014177104,0.00028642354,0.00000785004,0.0005847119,0.000035567078,0.9559317,0.00044937214,0.0006062969,0.023706514],"study_design_scores_gemma":[0.0007620329,0.00020335622,0.076897755,0.0003434406,0.00003748101,0.000013051011,0.0016107205,0.0056379912,0.90165436,0.0001527945,0.012288891,0.00039811427],"about_ca_topic_score_codex":0.00011221813,"about_ca_topic_score_gemma":0.000078320525,"teacher_disagreement_score":0.0612032,"about_ca_system_score_codex":0.00003060287,"about_ca_system_score_gemma":0.0002932165,"threshold_uncertainty_score":0.5029337},"labels":[],"label_agreement":null},{"id":"W4205102630","doi":"10.1002/btpr.3231","title":"Role of membrane structure on the filtrate flux during monoclonal antibody filtration through virus retentive membranes","year":2022,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Bristol-Myers Squibb Canada","keywords":"Membrane; Filtration (mathematics); Monoclonal antibody; Flux (metallurgy); Chemistry; Chromatography; Virus; Virology; Antibody; Medicine; Immunology; Biochemistry; Mathematics","score_opus":0.009138219697027425,"score_gpt":0.24696647674827107,"score_spread":0.23782825705124366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205102630","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99475527,0.0023234144,0.000030835312,0.001775646,0.000080752616,0.00052666484,0.0002669861,0.000047540132,0.0001928814],"genre_scores_gemma":[0.99899393,0.00011914263,0.00030083876,0.000069931215,0.000036751593,0.00010628729,0.00025324768,0.000014712416,0.00010514168],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987983,0.00016844043,0.00023290666,0.00040739833,0.0001861532,0.00020681259],"domain_scores_gemma":[0.9991094,0.000013381791,0.00018965748,0.00060971273,0.000058688485,0.000019158857],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016933824,0.00015395199,0.00015064633,0.000046730933,0.00030697387,0.0000117803,0.00045119505,0.00024371166,0.00020358655],"category_scores_gemma":[0.000065038505,0.00012187814,0.000079371996,0.0002061938,0.0004132877,0.0000057836955,0.00019638719,0.00028710737,0.0000025332674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024002483,0.00009875979,0.0004394241,0.000023283576,0.000057284302,0.0000015711952,0.000083272236,0.000043207336,0.9941257,0.0040078494,0.000023330585,0.00085629587],"study_design_scores_gemma":[0.00026454582,0.00027650813,0.0024478084,0.000004319988,0.000010988283,0.000021862883,0.00035211552,0.00005439102,0.9849828,0.00086946035,0.010586804,0.0001283936],"about_ca_topic_score_codex":0.000011313331,"about_ca_topic_score_gemma":0.000008194631,"teacher_disagreement_score":0.010563473,"about_ca_system_score_codex":0.000019970677,"about_ca_system_score_gemma":0.000049444112,"threshold_uncertainty_score":0.49700463},"labels":[],"label_agreement":null},{"id":"W4210278798","doi":"10.1016/j.chroma.2022.462881","title":"Dry-compression packing of hydroxyapatite nanoparticles within a flat cuboid chromatography device and its use for fast protein separation","year":2022,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; National Research Council Canada; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chromatography; Chemistry; Cuboid; Elution; Volumetric flow rate; Packed bed; Pressure drop; Analytical Chemistry (journal)","score_opus":0.01717038833607729,"score_gpt":0.27209311162758576,"score_spread":0.25492272329150845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210278798","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955074,0.002517653,0.0011789568,0.00007836728,0.0000685575,0.0005690649,0.000059204736,0.000007961107,0.000012791165],"genre_scores_gemma":[0.9970193,0.00006030515,0.002702762,0.00004886209,0.000040993036,0.000085153246,0.000020713956,0.000015687443,0.0000062328113],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985878,0.00019024959,0.0005896949,0.00020590295,0.00027310295,0.00015325409],"domain_scores_gemma":[0.9986672,0.000026435833,0.0007424741,0.00019952936,0.00027275013,0.00009160835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00060180377,0.00013859804,0.00023939919,0.00019219707,0.0002048453,0.000039998667,0.0001679049,0.00006727078,0.000009470138],"category_scores_gemma":[0.00008547775,0.00012563134,0.00022595917,0.00029058123,0.00007192805,0.000040114955,0.00007369805,0.00012016031,1.0742091e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034037395,0.00012959671,0.014423071,0.00010967235,0.000089060595,0.0000012611436,0.00028171792,0.000103218765,0.9837802,0.00020078098,0.000046280777,0.00049475307],"study_design_scores_gemma":[0.0011945679,0.0009433749,0.010663816,0.00008427446,0.000045227433,0.000040285948,0.00019841111,0.0012393454,0.97950274,0.00036342265,0.005553074,0.00017143344],"about_ca_topic_score_codex":0.0000066917473,"about_ca_topic_score_gemma":0.0000087740655,"teacher_disagreement_score":0.0055067935,"about_ca_system_score_codex":0.000009310711,"about_ca_system_score_gemma":0.00007392693,"threshold_uncertainty_score":0.51230973},"labels":[],"label_agreement":null},{"id":"W4210514446","doi":"10.1016/j.xphs.2022.01.016","title":"Effects of Transportation of IV Bags Containing Protein Formulations Via Hospital Pneumatic Tube System: Particle Characterization by Multiple Methods","year":2022,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pfizer (Canada)","funders":"Pfizer","keywords":"Saline; Polyvinyl chloride; Particle (ecology); Chemistry; Chromatography; Particle size; Anesthesia; Medicine; Organic chemistry","score_opus":0.018994957835029667,"score_gpt":0.3365788144435305,"score_spread":0.3175838566085008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210514446","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.908555,0.000396613,0.09043974,0.00016496745,0.0000871695,0.00032328095,0.00002124471,0.000002866482,0.000009127186],"genre_scores_gemma":[0.99682987,0.000010844568,0.0030750653,0.000018661194,0.000016316117,0.000028173643,0.0000127109615,0.0000034635445,0.0000048987768],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987098,0.0003055446,0.0004821879,0.00011177757,0.00028026846,0.00011043504],"domain_scores_gemma":[0.9992457,0.000074922755,0.00042389892,0.000060570303,0.00012693835,0.000067987276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001304662,0.00006091697,0.00015164912,0.000031632262,0.00012422533,0.000008615671,0.00016715952,0.000027250075,0.0000189055],"category_scores_gemma":[0.00018784445,0.00005121729,0.000092097485,0.00019321818,0.00012465628,0.000024816527,0.00001697946,0.00008152828,1.2037995e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000846318,0.00018324291,0.0036279764,0.00012423984,0.000021433498,4.2014938e-7,0.00021153736,0.0000904403,0.990114,0.00024176031,0.0000017709558,0.005298563],"study_design_scores_gemma":[0.0005975589,0.0008213451,0.010035778,0.000022581848,0.000037288773,0.0000036142687,0.00022092574,0.010423312,0.9771881,0.000047787133,0.0005395853,0.0000621404],"about_ca_topic_score_codex":0.0000050027475,"about_ca_topic_score_gemma":5.110186e-7,"teacher_disagreement_score":0.088274874,"about_ca_system_score_codex":0.000022037588,"about_ca_system_score_gemma":0.00006813897,"threshold_uncertainty_score":0.20885803},"labels":[],"label_agreement":null},{"id":"W4220796118","doi":"10.1002/jssc.202200183","title":"Ultrahigh‐speed, ultrahigh‐resolution preparative separation of protein biopharmaceuticals using membrane chromatography","year":2022,"lang":"en","type":"article","venue":"Journal of Separation Science","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Chromatography; Resolution (logic); Chemistry; Membrane; Column chromatography; Fractionation; Chromatography column; Computer science; Artificial intelligence","score_opus":0.03461655613687097,"score_gpt":0.3742081459888305,"score_spread":0.33959158985195953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220796118","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9809274,0.0008798017,0.01697314,0.00015845413,0.00019835273,0.00046744742,0.000026626318,0.000006295437,0.00036246286],"genre_scores_gemma":[0.9974433,0.00004266312,0.002273247,0.000066346096,0.00007521631,0.000012797777,0.000011254855,0.000006391317,0.0000687408],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99773836,0.00026193322,0.00070236233,0.00028756727,0.0008143689,0.00019542594],"domain_scores_gemma":[0.9980327,0.000017061624,0.0008494428,0.00025868596,0.0007227443,0.00011934845],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021107967,0.00012220106,0.00019838143,0.00025859504,0.00038493786,0.00004476127,0.00039378143,0.00005335956,0.00010659585],"category_scores_gemma":[0.00020064328,0.00011419078,0.00013155761,0.0009033439,0.00045769333,0.00008129679,0.00006591755,0.00015712218,0.0000015749195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027213743,0.00015804563,0.00029933982,0.000012779429,0.00001931415,8.7575313e-7,0.0002882718,0.008677747,0.9895436,0.0005467267,0.000034652632,0.00014651101],"study_design_scores_gemma":[0.00052347395,0.0005490742,0.0013099234,0.000010047811,0.00001960715,0.00008357117,0.00022934032,0.0053311633,0.9871962,0.00015077721,0.0044696154,0.00012720362],"about_ca_topic_score_codex":0.000008562485,"about_ca_topic_score_gemma":0.000001975358,"teacher_disagreement_score":0.016515924,"about_ca_system_score_codex":0.00008405584,"about_ca_system_score_gemma":0.0006139962,"threshold_uncertainty_score":0.46565646},"labels":[],"label_agreement":null},{"id":"W4220848908","doi":"10.1016/j.bej.2022.108417","title":"Comparison of the performance of anion exchange membrane materials for adenovirus purification using laterally-fed membrane chromatography","year":2022,"lang":"en","type":"article","venue":"Biochemical Engineering Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University Medical Centre; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Research Foundation; McMaster University","keywords":"Membrane; Elution; Chromatography; Lysis; Chemistry; Ion exchange; Ion chromatography; Ion; Biochemistry; Organic chemistry","score_opus":0.018159420345971698,"score_gpt":0.26035073083957416,"score_spread":0.24219131049360246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220848908","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968403,0.001072943,0.0015056039,0.000044730827,0.00022288204,0.00024244603,0.000061795545,0.0000060449443,0.0000032358823],"genre_scores_gemma":[0.997967,0.000053335072,0.0017899646,0.000010466027,0.00009458029,0.000029284827,0.000034649296,0.000014052671,0.0000066565594],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907196,0.000045138648,0.00039393298,0.00013712756,0.00021567848,0.00013616543],"domain_scores_gemma":[0.99934965,0.000009483912,0.0002578769,0.00022564238,0.00011701855,0.00004030026],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045798693,0.000097940414,0.0001754981,0.00004891436,0.000104196326,0.000010026467,0.00026132556,0.000068309746,0.000036030902],"category_scores_gemma":[0.00007603652,0.0000838724,0.000111754045,0.00012808263,0.000040951916,0.0000052141086,0.0000778035,0.0001080206,7.3345994e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014134539,0.000076226366,0.00051735167,0.00019216994,0.00002803894,3.995438e-8,0.000051729647,0.0019279632,0.9969282,0.000013178283,0.000040114694,0.000083604056],"study_design_scores_gemma":[0.0003640977,0.00013642998,0.0012429197,0.000022138951,0.000017365659,0.000023087718,0.000020430452,0.0039417306,0.99240005,0.0000019239872,0.0017395489,0.000090294074],"about_ca_topic_score_codex":0.0000026821285,"about_ca_topic_score_gemma":7.938876e-8,"teacher_disagreement_score":0.0045282054,"about_ca_system_score_codex":0.000030234958,"about_ca_system_score_gemma":0.00004689506,"threshold_uncertainty_score":0.34202173},"labels":[],"label_agreement":null},{"id":"W4220978071","doi":"10.1016/j.ohx.2022.e00291","title":"REVOLVER: A low-cost automated protein purifier based on parallel preparative gravity column workflows","year":2022,"lang":"en","type":"article","venue":"HardwareX","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Workflow; Pipeline (software); Scalability; Computer science; Process (computing); Protein purification; Chromatography; Chemistry; Operating system; Database","score_opus":0.011749797309923461,"score_gpt":0.2603375260962783,"score_spread":0.24858772878635485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220978071","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9581891,0.0007218113,0.011719929,0.002152277,0.0005133788,0.009706923,0.0011070978,0.00080102263,0.015088506],"genre_scores_gemma":[0.9918232,0.0000046962527,0.0013831797,0.00068086165,0.00005597565,0.0025628088,0.00068095897,0.000026081676,0.0027822435],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980114,0.00042838912,0.00027984232,0.000648474,0.00032478155,0.00030710682],"domain_scores_gemma":[0.9987602,0.000014722013,0.00013761963,0.0008609565,0.00010192454,0.00012456463],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048356666,0.00020511136,0.00019810698,0.00004655557,0.00035049857,0.00003609507,0.00033810586,0.00011114108,0.0006049099],"category_scores_gemma":[0.00018134403,0.00021600546,0.00014493256,0.00021196943,0.000084173764,0.000004127559,0.00014235517,0.00023361015,0.000053718763],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013958649,0.008316883,0.01802532,0.00040428335,0.00048265702,0.00013678789,0.0011536764,0.04668526,0.6110014,0.0019813157,0.27750298,0.020350799],"study_design_scores_gemma":[0.0032326113,0.0011091945,0.013975079,0.000047141246,0.000028172271,0.000008561757,0.00013709503,0.040482502,0.08250506,0.00036305166,0.8571457,0.00096582476],"about_ca_topic_score_codex":0.000024485304,"about_ca_topic_score_gemma":0.000024695551,"teacher_disagreement_score":0.5796427,"about_ca_system_score_codex":0.00009363376,"about_ca_system_score_gemma":0.00024830183,"threshold_uncertainty_score":0.88084465},"labels":[],"label_agreement":null},{"id":"W4225663878","doi":"10.2139/ssrn.4010363","title":"Fast and High-Resolution Fractionation of Positional Isomers of a PEGylated Protein Using Membrane Chromatography","year":2022,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Fractionation; Chromatography; Chemistry; Resolution (logic); Artificial intelligence; Computer science","score_opus":0.005275605160684226,"score_gpt":0.22283302733822802,"score_spread":0.21755742217754379,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225663878","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9846738,0.0021060945,0.0128086265,0.00015935775,0.000028999895,0.0001660109,0.000026642914,0.000003111608,0.000027357546],"genre_scores_gemma":[0.9992204,0.00023859392,0.00039289368,0.000011888673,0.000025597503,0.000011570622,0.00006276,0.000006780403,0.000029527639],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990404,0.00012854561,0.00022311154,0.00012953523,0.00019490966,0.0002834447],"domain_scores_gemma":[0.9995358,0.00000413441,0.00024180721,0.00008854069,0.0001041894,0.000025528298],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006223989,0.00006435066,0.000089094145,0.000096766256,0.00016844149,0.000004651851,0.00007488541,0.000042899745,0.000033834975],"category_scores_gemma":[0.00002274156,0.00006877593,0.000061028513,0.0001470923,0.00006381184,0.000008445715,0.000032651005,0.00029586593,8.1369144e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020097129,0.0001098896,0.0007155109,0.0000112678135,0.000091370996,1.2197846e-7,0.000023345468,0.00084475346,0.9887286,0.007528014,0.0000022055228,0.0017439506],"study_design_scores_gemma":[0.0057338327,0.004284595,0.033798065,0.000051669453,0.00016569113,0.0014031971,0.0041880966,0.0076779,0.87344384,0.06665499,0.0018632618,0.0007348705],"about_ca_topic_score_codex":0.00006908781,"about_ca_topic_score_gemma":0.000023788332,"teacher_disagreement_score":0.11528477,"about_ca_system_score_codex":0.00010514826,"about_ca_system_score_gemma":0.0005413,"threshold_uncertainty_score":0.28046012},"labels":[],"label_agreement":null},{"id":"W4226186746","doi":"10.1101/2021.12.29.474408","title":"Multi-Wavelength Analytical Ultracentrifugation of Biopolymer Mixtures and Interactions","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of Lethbridge","funders":"National Institutes of Health; University of Alberta; University of Montana; National Science Foundation","keywords":"Biopolymer; Analytical Ultracentrifugation; Ultracentrifuge; Analyte; Chemistry; Biological system; Characterization (materials science); Nanotechnology; Chromatography; Materials science; Polymer","score_opus":0.015185310066711042,"score_gpt":0.2514966254853611,"score_spread":0.23631131541865008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226186746","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99016297,0.0032471905,0.005544133,0.00016898233,0.00032064103,0.0003469788,0.00017179037,0.00003137976,0.00000591519],"genre_scores_gemma":[0.9928155,0.00064991513,0.006234536,0.00006593934,0.0001338258,0.00005459636,0.0000043227074,0.000031987947,0.000009368655],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99840385,0.00014180846,0.00040505044,0.0006900908,0.0001528484,0.00020636639],"domain_scores_gemma":[0.99830467,0.00002088783,0.00025758767,0.0008189108,0.00045098507,0.00014693983],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026223334,0.00025762277,0.00029208115,0.00009006832,0.0000704483,0.000070454465,0.0001830023,0.00037556535,0.00003699427],"category_scores_gemma":[0.0004533956,0.00027569663,0.00012580572,0.00014880291,0.00017576838,0.00000856266,0.00022624269,0.0003156064,0.0000023561984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027444037,0.00020775113,0.0059651104,0.00015148701,0.00012433664,0.0000023391804,0.0000073917276,0.000005695086,0.9933739,0.00009060791,0.000030787556,0.000013192993],"study_design_scores_gemma":[0.000301328,0.000025681251,0.08982928,0.000069958325,0.000063305975,3.018924e-8,0.000008307161,0.0007946288,0.9065488,3.1313456e-7,0.0020856203,0.0002727164],"about_ca_topic_score_codex":0.00003553767,"about_ca_topic_score_gemma":0.0000069328353,"teacher_disagreement_score":0.08682503,"about_ca_system_score_codex":0.00003472954,"about_ca_system_score_gemma":0.0002977694,"threshold_uncertainty_score":0.99996954},"labels":[],"label_agreement":null},{"id":"W4232113508","doi":"10.1007/978-3-540-29678-2_967","title":"Chaperones: Protein Trafficking","year":2008,"lang":"en","type":"book-chapter","venue":"","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Human trafficking; Criminology; Psychology","score_opus":0.018939110778526037,"score_gpt":0.2267042431446403,"score_spread":0.20776513236611427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4232113508","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0015030956,0.0035354153,0.00078604196,0.00017929616,0.00007086953,0.0007405134,0.00002471297,0.000055758446,0.9931043],"genre_scores_gemma":[0.08876019,0.00069051306,0.00067457516,0.00020313307,0.00026504666,0.00003849652,0.0002366629,0.000053523,0.9090779],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99893254,0.00001267386,0.0002444847,0.0004950686,0.0001516828,0.00016352886],"domain_scores_gemma":[0.9991519,0.0000026482464,0.000101637124,0.0005811246,0.00008328341,0.00007944202],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008717119,0.00024564104,0.00018408007,0.00003439895,0.00007016521,0.000012044323,0.00020207393,0.00045808847,0.00057603297],"category_scores_gemma":[0.000026532487,0.00022988865,0.00015621724,0.000009081964,0.00012625294,0.0000011964094,0.00006615649,0.00015747288,0.00017325867],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055573037,0.00046569217,0.000052043237,0.0005281652,0.0007879773,0.000074361895,0.00046919135,0.000021258218,0.441464,0.23597074,0.052333176,0.26727766],"study_design_scores_gemma":[0.00015495809,0.000093619106,0.000015695223,0.000020304398,0.0000062066238,0.000015067473,0.000004009661,0.0000043644504,0.015357486,0.00026436214,0.983758,0.00030597526],"about_ca_topic_score_codex":0.0000025620748,"about_ca_topic_score_gemma":0.000013560333,"teacher_disagreement_score":0.9314248,"about_ca_system_score_codex":0.000017070843,"about_ca_system_score_gemma":0.000113263246,"threshold_uncertainty_score":0.93745875},"labels":[],"label_agreement":null},{"id":"W4233559295","doi":"10.1007/978-1-62703-691-7_5","title":"Medium-Throughput Production of Recombinant Human Proteins: Protein Production in E. coli","year":2013,"lang":"en","type":"book-chapter","venue":"Methods in molecular biology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Recombinant DNA; Protein purification; Chemistry; Affinity chromatography; Size-exclusion chromatography; FLAG-tag; Chromatography; Crystallization; Protein crystallization; Escherichia coli; Biochemistry; Combinatorial chemistry; Enzyme; Gene; Organic chemistry","score_opus":0.032359385730347766,"score_gpt":0.35746481614800024,"score_spread":0.3251054304176525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4233559295","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.31010205,0.042383257,0.37520975,0.010187086,0.01332063,0.078730926,0.00014573144,0.00038985765,0.16953072],"genre_scores_gemma":[0.0551856,0.0011368268,0.7473866,0.00019510303,0.000650938,0.0047234423,0.0011749404,0.0003229123,0.18922368],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9957183,0.0011350011,0.0011586638,0.0014119968,0.00017089874,0.00040511639],"domain_scores_gemma":[0.9976477,0.00001275079,0.00065655453,0.0013157504,0.00029821132,0.00006905791],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0026044804,0.00048726852,0.0007707624,0.00035426454,0.000052430994,0.000010049014,0.00042723538,0.0012228271,0.00010908989],"category_scores_gemma":[0.0012555388,0.00048419536,0.00019342055,0.00014133235,0.00053809874,0.000007742704,0.00022377817,0.00061535655,0.000010610984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000080987855,0.00016466193,0.00007117378,0.0002053276,0.000049720045,0.0000034588595,0.00004067461,0.000007619896,0.972803,0.011483006,0.00008198796,0.015008369],"study_design_scores_gemma":[0.0004242243,0.0005335069,0.00021884231,0.00020523688,0.00001829221,0.000010651064,0.000012617573,0.0000032082419,0.88278323,0.06372241,0.051586423,0.00048134712],"about_ca_topic_score_codex":0.0001350572,"about_ca_topic_score_gemma":0.00012482732,"teacher_disagreement_score":0.37217683,"about_ca_system_score_codex":0.00012337608,"about_ca_system_score_gemma":0.00022645744,"threshold_uncertainty_score":0.999761},"labels":[],"label_agreement":null},{"id":"W4234951553","doi":"10.1016/j.clinbiochem.2006.04.004","title":"Editorial","year":2006,"lang":"es","type":"editorial","venue":"Clinical Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Chemistry; AutoAnalyzer; Lactate dehydrogenase; Albumin; Uric acid; Creatinine; Alkaline phosphatase; Urea; Internal medicine; Biochemistry; Endocrinology; Chromatography; Enzyme; Biology; Medicine","score_opus":0.012005177470608527,"score_gpt":0.3367657998012,"score_spread":0.3247606223305915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4234951553","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005716097,0.0038124998,0.000100130455,0.0002765373,0.97976035,0.00050283107,0.0016410336,0.00007242821,0.008118094],"genre_scores_gemma":[0.017230831,0.0019328994,0.0002701469,0.000107222426,0.9594602,0.00009710274,0.011298542,0.00011179311,0.00949126],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9927632,0.00042030573,0.002290607,0.002629597,0.0010809692,0.0008153081],"domain_scores_gemma":[0.9940677,0.0005184476,0.0010149458,0.0027654762,0.0010692984,0.0005641198],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0021860914,0.0009335817,0.0010938579,0.000037551534,0.00023553162,0.00020683277,0.0014711454,0.008825441,0.00015447626],"category_scores_gemma":[0.01019463,0.0009744144,0.0012871057,0.00017466782,0.0012041775,0.0000055296896,0.0006272338,0.002333667,0.00029907166],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004717659,0.00081348984,0.00077178626,0.0003164578,0.0001844078,0.0000036736299,0.0000015707307,7.189257e-7,0.022817392,0.000006956047,0.9713863,0.0032254402],"study_design_scores_gemma":[0.0017163298,0.00035355322,0.00012850907,0.00009046282,0.00014603537,0.0000017027352,0.000008208616,0.0000034600332,0.045142822,0.00009427562,0.95131177,0.0010028459],"about_ca_topic_score_codex":0.000041064395,"about_ca_topic_score_gemma":0.000005639336,"teacher_disagreement_score":0.022325428,"about_ca_system_score_codex":0.00012458197,"about_ca_system_score_gemma":0.0022507145,"threshold_uncertainty_score":0.999968},"labels":[],"label_agreement":null},{"id":"W4242439596","doi":"10.1002/biot.200990041","title":"In this issue: Biotechnology Journal 5/2009","year":2009,"lang":"en","type":"article","venue":"Biotechnology Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Bioprocess; Adsorption; Acetophenone; Biocatalysis; Chemistry; Alcohol dehydrogenase; In silico; Filtration (mathematics); Chromatography; Chemical engineering; Desorption; Catalysis; Organic chemistry; Enzyme; Biochemistry; Engineering","score_opus":0.007111583583211357,"score_gpt":0.2575749922758147,"score_spread":0.25046340869260336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242439596","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7688005,0.021637348,0.011876767,0.19292428,0.0013870057,0.00046224627,0.000015073811,0.00015716904,0.0027396095],"genre_scores_gemma":[0.9845345,0.006784297,0.0048928936,0.0021723495,0.00054211076,0.0000053599138,0.000006108309,0.00001888566,0.001043485],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981992,0.00013198706,0.0005785744,0.00037808935,0.00016990202,0.00054225104],"domain_scores_gemma":[0.9989056,0.000007349006,0.00027884427,0.0005593484,0.00011314549,0.00013570911],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008546677,0.00022684316,0.0002698697,0.00046316092,0.00023720587,0.000057276953,0.00076301495,0.0013483767,0.00039392093],"category_scores_gemma":[0.00048524092,0.00020489574,0.00014295014,0.0003727267,0.0002896335,0.000016485457,0.00008481066,0.0013809616,0.00008414652],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015205985,0.00029993744,0.0007577632,0.0000036566014,0.000038771923,0.0001450692,0.000037383532,0.000006526363,0.85785687,0.0021169372,0.02547608,0.11310893],"study_design_scores_gemma":[0.00092161907,0.0007588609,0.0017946777,0.000013112224,0.000008373862,0.004287769,0.00009553511,0.000015575548,0.38948885,0.0058102943,0.5965637,0.0002416428],"about_ca_topic_score_codex":0.000003803874,"about_ca_topic_score_gemma":0.00000920725,"teacher_disagreement_score":0.5710876,"about_ca_system_score_codex":0.00007638439,"about_ca_system_score_gemma":0.00017815531,"threshold_uncertainty_score":0.9999481},"labels":[],"label_agreement":null},{"id":"W4254423239","doi":"10.1201/b17219-42","title":"Physicochemical characteristics of RAP binder blends","year":2014,"lang":"en","type":"book-chapter","venue":"","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Materials science; Composite material; Polymer science","score_opus":0.011811974653983658,"score_gpt":0.23177517945525736,"score_spread":0.2199632048012737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4254423239","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007289534,0.00037993735,0.0021226022,0.00009594083,0.00014531854,0.00025044064,0.00009011323,0.000020505762,0.9896056],"genre_scores_gemma":[0.557003,0.00013355831,0.00019780512,0.00012544208,0.00024545525,0.000008576548,0.00058894197,0.000031765376,0.4416654],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991002,0.000010896188,0.0003051395,0.00034131767,0.00012781926,0.00011459286],"domain_scores_gemma":[0.9989672,0.0000070820847,0.00019279901,0.00062387245,0.0001458889,0.000063172665],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000096774536,0.00019958241,0.00027635827,0.000025246172,0.000017661006,0.0000061043243,0.00018658247,0.00041063086,0.00051893026],"category_scores_gemma":[0.000031628628,0.0001854836,0.0001781168,0.000008033706,0.00012093226,5.254585e-7,0.00006302704,0.00012651726,0.000039477593],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015305172,0.000058724712,0.00006284715,0.00018403784,0.00016844817,6.034806e-7,0.00001430046,9.705014e-8,0.7760068,0.17655142,0.0021884905,0.044611156],"study_design_scores_gemma":[0.00021515343,0.0001061378,0.00024061534,0.000022721064,0.000034447636,0.0000021482267,0.0000022189681,0.0000039407805,0.36646438,0.0031719126,0.62942195,0.0003143913],"about_ca_topic_score_codex":9.1156886e-7,"about_ca_topic_score_gemma":0.0000015117772,"teacher_disagreement_score":0.62723345,"about_ca_system_score_codex":0.000007960361,"about_ca_system_score_gemma":0.00008160026,"threshold_uncertainty_score":0.75638014},"labels":[],"label_agreement":null},{"id":"W4254943653","doi":"10.1002/14356007.b03_11.pub2","title":"Bioseparation","year":2012,"lang":"en","type":"other","venue":"Ullmann's Encyclopedia of Industrial Chemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Chromatography; Chemistry; Adsorption; Elution; Membrane; Isotachophoresis; Size-exclusion chromatography; Ion exchange; Electrodialysis; Electrolyte; Ion","score_opus":0.016998726507768413,"score_gpt":0.24924264967302748,"score_spread":0.23224392316525908,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4254943653","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0024135103,0.0044195307,0.00006091685,0.000062726205,0.0005161638,0.0004301807,0.00029496002,0.000055318513,0.99174666],"genre_scores_gemma":[0.019413019,0.0020055585,0.00041303324,0.000036834772,0.006670152,0.000101403144,0.0023601465,0.00032789444,0.968672],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.998617,0.00005012226,0.00039445562,0.00043971956,0.00022377155,0.00027491205],"domain_scores_gemma":[0.99856883,0.00001007397,0.00044244618,0.00076982647,0.00006175369,0.00014705566],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020272842,0.00031367075,0.00032090792,0.000042656884,0.000027344342,0.000008875711,0.00034156808,0.0014184758,0.002796814],"category_scores_gemma":[0.000275681,0.0003223812,0.00015559305,0.0000999459,0.00014887522,0.000002812951,0.00010066153,0.0002718978,0.000048731315],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000107415966,0.00024789327,0.0014424397,0.00018728049,0.00015075118,0.0000010830477,0.000021666216,0.0000010444177,0.058797378,0.00006131906,0.9281321,0.010849628],"study_design_scores_gemma":[0.00045615915,0.00002899708,0.000018786575,0.0000455794,0.000037761085,0.0000025412558,0.000014303384,3.7679976e-7,0.09751685,0.000010065661,0.90157974,0.00028884242],"about_ca_topic_score_codex":0.000040743766,"about_ca_topic_score_gemma":0.0000067102133,"teacher_disagreement_score":0.03871947,"about_ca_system_score_codex":0.000021459915,"about_ca_system_score_gemma":0.00022778838,"threshold_uncertainty_score":0.9999228},"labels":[],"label_agreement":null},{"id":"W4280610206","doi":"10.1016/j.jchromb.2022.123292","title":"Fast and high-resolution fractionation of positional isomers of a PEGylated protein using membrane chromatography","year":2022,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; McMaster University","keywords":"Chemistry; Lysozyme; Chromatography; Fractionation; Resolution (logic); Structural isomer; PEGylation; Column chromatography; Ion chromatography; Analytical Chemistry (journal); Organic chemistry; Polyethylene glycol; Biochemistry","score_opus":0.007799766077052459,"score_gpt":0.23238350820308212,"score_spread":0.22458374212602966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280610206","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944078,0.0015999668,0.0034698322,0.00011825937,0.00007182965,0.00020514564,0.00007355591,0.0000036352887,0.00005],"genre_scores_gemma":[0.99661803,0.000071583054,0.0031939899,0.000020914873,0.000032116768,0.000009409372,0.000041792646,0.000009111532,0.0000030270608],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987155,0.00015877513,0.0005209209,0.00013796493,0.00036881806,0.000098020355],"domain_scores_gemma":[0.9987148,0.000011363276,0.0007993551,0.00013969792,0.00027972573,0.00005505479],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041728324,0.00009722492,0.00020359509,0.0003505809,0.00011549448,0.0000072761186,0.00011652762,0.00006649258,0.00006464155],"category_scores_gemma":[0.000029375771,0.00009864649,0.00020113861,0.0004044086,0.00015223098,0.000018579187,0.000043666652,0.00012513585,4.7989364e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028332163,0.00025478977,0.003730354,0.00006458432,0.0001608403,0.0000011621827,0.000054837335,0.0006758656,0.99390954,0.00037417398,0.000031418338,0.0004591442],"study_design_scores_gemma":[0.002682951,0.0016195881,0.124423705,0.000092874994,0.000121792305,0.00040474723,0.00055130717,0.0011540083,0.865802,0.0011372842,0.0017204579,0.00028928867],"about_ca_topic_score_codex":0.000030966,"about_ca_topic_score_gemma":0.0000018273873,"teacher_disagreement_score":0.12810752,"about_ca_system_score_codex":0.000016955086,"about_ca_system_score_gemma":0.00010960359,"threshold_uncertainty_score":0.40226868},"labels":[],"label_agreement":null},{"id":"W4281251203","doi":"10.1016/j.chroma.2022.463168","title":"Coupling of multivariate curve resolution-alternating least squares and mechanistic hard models to investigate antibody purification from human plasma using ion exchange chromatography","year":2022,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Chemistry; Chromatography; Elution; Analytical Chemistry (journal); Ion chromatography; Absorbance; Matrix (chemical analysis); Ion exchange; Ion","score_opus":0.04075783248515812,"score_gpt":0.29255666073760606,"score_spread":0.2517988282524479,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281251203","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97171223,0.0019289461,0.025702983,0.00006301981,0.00014382329,0.00029386955,0.00012856025,0.000011212346,0.000015344134],"genre_scores_gemma":[0.99070203,0.00009955837,0.00893369,0.000030334186,0.00010343072,0.00001921699,0.000086438056,0.000023086795,0.0000022055992],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982325,0.00014674866,0.00071672985,0.00032181537,0.0003847355,0.00019751406],"domain_scores_gemma":[0.9984047,0.000027116615,0.0008601362,0.00029924742,0.00025094766,0.00015785042],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007853694,0.0001794679,0.0003026917,0.00037691588,0.00033988451,0.00004357433,0.00027782333,0.00008002256,0.000012659388],"category_scores_gemma":[0.00006825092,0.00018818791,0.00019503494,0.0003734338,0.00010771728,0.000029698444,0.00014400443,0.00018914836,1.6944162e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012810044,0.00012949196,0.0053576226,0.000061607396,0.00012217023,0.0000030613792,0.00040996412,0.0084068775,0.9848108,0.0004243856,0.000019759702,0.00012612234],"study_design_scores_gemma":[0.004953039,0.0019986096,0.10812437,0.0006270419,0.00035442555,0.00022739804,0.0020050167,0.21011424,0.6580851,0.010708469,0.0016083505,0.0011939298],"about_ca_topic_score_codex":0.00021965624,"about_ca_topic_score_gemma":0.000012569505,"teacher_disagreement_score":0.32672572,"about_ca_system_score_codex":0.00002707299,"about_ca_system_score_gemma":0.000071824565,"threshold_uncertainty_score":0.767408},"labels":[],"label_agreement":null},{"id":"W4281262351","doi":"10.1016/j.ab.2022.114728","title":"Multi-wavelength analytical ultracentrifugation of biopolymer mixtures and interactions","year":2022,"lang":"en","type":"review","venue":"Analytical Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of Lethbridge","funders":"National Institute of General Medical Sciences; National Institutes of Health; University of Alberta; University of Montana; National Science Foundation","keywords":"Analytical Ultracentrifugation; Characterization (materials science); Biopolymer; Analyte; Ultracentrifuge; Wavelength; Biological system; Chemistry; Dimension (graph theory); Nanotechnology; Computer science; Biochemical engineering; Materials science; Chromatography; Mathematics; Polymer; Optoelectronics; Engineering","score_opus":0.04516102024246747,"score_gpt":0.35120989146524206,"score_spread":0.3060488712227746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281262351","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004502662,0.99774146,0.00021797486,0.00007321374,0.00007379206,0.0003080394,0.00030936935,0.000015175264,0.00081073056],"genre_scores_gemma":[0.007157099,0.9893247,0.00032859913,0.000049062044,0.00013194248,0.0000633512,0.0014233057,0.0000317308,0.0014902058],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99802554,0.00013241445,0.00067606976,0.0007091719,0.00021383261,0.00024296314],"domain_scores_gemma":[0.99865836,0.000101865284,0.00029282487,0.00066605903,0.00009609104,0.00018480302],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024751798,0.0003387068,0.00072274194,0.00008062688,0.00009395741,0.000024935218,0.00028032644,0.00038058878,0.000518169],"category_scores_gemma":[0.00090061233,0.000305579,0.00045748235,0.00025512165,0.000325974,0.0000037332013,0.00019619195,0.00041540663,0.000006714988],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007730192,0.001019319,0.00008194828,0.008671456,0.0011128729,0.00000913223,0.000023096554,5.922347e-7,0.010558758,0.0003177908,0.0018243105,0.9763034],"study_design_scores_gemma":[0.00020603277,0.000049458366,0.000008710737,0.00022504141,0.00054381357,0.000046927,0.000039546783,0.00023711394,0.009730443,0.000006826502,0.98855287,0.00035319882],"about_ca_topic_score_codex":0.000009348422,"about_ca_topic_score_gemma":0.0000012859375,"teacher_disagreement_score":0.98672855,"about_ca_system_score_codex":0.00005337714,"about_ca_system_score_gemma":0.00026274976,"threshold_uncertainty_score":0.9999396},"labels":[],"label_agreement":null},{"id":"W4289653714","doi":"10.1101/2022.08.01.502380","title":"Formulation excipients and their role in insulin stability and association state in formulation","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Stanford Maternal and Child Health Research Institute; Natural Sciences and Engineering Research Council of Canada; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Defense; National Defense Science and Engineering Graduate; Stanford Diabetes Research Center; National Institutes of Health; American Diabetes Association","keywords":"Excipient; Insulin; Chemistry; Monomer; Zinc; Chromatography; Insulin lispro; Chemical engineering; Organic chemistry; Polymer; Human insulin; Internal medicine; Medicine; Engineering","score_opus":0.010231300802068579,"score_gpt":0.21784632991144004,"score_spread":0.20761502910937146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4289653714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967099,0.0015498643,0.00041802085,0.00007525336,0.00010974627,0.0008964537,0.0002079896,0.000026226877,0.0000065794416],"genre_scores_gemma":[0.9988898,0.00045429968,0.00029507262,0.00004303123,0.000034700424,0.0002452198,0.000007973083,0.000027748865,0.000002142519],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99811757,0.00026367992,0.00046429763,0.0007202195,0.00017082207,0.0002633981],"domain_scores_gemma":[0.99892783,0.000032141397,0.00030959764,0.00050591934,0.00014395468,0.000080541206],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014407805,0.0002459349,0.00025916618,0.0001451149,0.00007836952,0.00006623618,0.00013524668,0.0003348788,0.000013459938],"category_scores_gemma":[0.0003852406,0.00027414857,0.00004070006,0.0002042482,0.000024972847,0.000023639353,0.00038481026,0.0003789232,6.395299e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009617815,0.00013321654,0.5665108,0.000108739805,0.00001936482,5.4685546e-7,0.00008833452,0.000089180285,0.43283522,0.00007193566,0.0000017410937,0.000044763994],"study_design_scores_gemma":[0.0006680466,0.00004488208,0.8913091,0.000023958268,0.000005357292,3.1195526e-9,0.000012983101,0.001615773,0.10502054,0.000075372875,0.0009499218,0.0002740545],"about_ca_topic_score_codex":0.00014244493,"about_ca_topic_score_gemma":0.0001183899,"teacher_disagreement_score":0.32781467,"about_ca_system_score_codex":0.000376899,"about_ca_system_score_gemma":0.00017969737,"threshold_uncertainty_score":0.9999711},"labels":[],"label_agreement":null},{"id":"W4289856875","doi":"10.3390/ijms23158663","title":"Recent Advances and Future Directions in Downstream Processing of Therapeutic Antibodies","year":2022,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Downstream (manufacturing); Computer science; Quality by Design; Risk analysis (engineering); Biochemical engineering; Process (computing); Downstream processing; Critical quality attributes; Quality (philosophy); New product development; Robustness (evolution); Process development; Manufacturing engineering; Engineering; Operations management; Business; Chemistry","score_opus":0.02967784788348237,"score_gpt":0.36049817010608964,"score_spread":0.33082032222260727,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4289856875","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00067587884,0.9982352,0.00008581289,0.00019384631,0.00034923007,0.0001011726,0.000012944235,0.0000012865396,0.00034458554],"genre_scores_gemma":[0.001900632,0.997523,0.00043073043,0.000024311441,0.00009134104,0.000008387492,0.000009492955,0.00000523969,0.0000068805707],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99874246,0.0001536974,0.00045914,0.00019128507,0.00037179148,0.00008160328],"domain_scores_gemma":[0.9991097,0.000020320214,0.00058996887,0.0000834572,0.00016854667,0.000028025197],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005792196,0.00011370976,0.00030038372,0.00021909758,0.00005127267,0.00003446276,0.0004631142,0.00006249471,0.000026696283],"category_scores_gemma":[0.00008224962,0.00008558303,0.00013248708,0.00021686517,0.00020933728,0.00001541645,0.00008297393,0.00014647318,9.945614e-8],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000904789,0.000054489912,0.00006220706,0.00020638235,0.000041711217,0.0000051656266,0.000038184477,0.0000053607855,0.00015352633,0.0000596857,0.0000017203416,0.9993625],"study_design_scores_gemma":[0.00008909295,0.000104983905,0.000049572922,0.0003188077,0.000028613971,0.00012866872,0.00014625597,0.0000025499423,0.00024058274,0.00014740715,0.9986621,0.00008135503],"about_ca_topic_score_codex":0.0000016801397,"about_ca_topic_score_gemma":0.000004408835,"teacher_disagreement_score":0.99928117,"about_ca_system_score_codex":0.000029446743,"about_ca_system_score_gemma":0.00038849018,"threshold_uncertainty_score":0.34899744},"labels":[],"label_agreement":null},{"id":"W4291340499","doi":"10.2139/ssrn.4189397","title":"Sequence-Based Prediction of Ph-Dependent Protein Solubility Using Camsol","year":2022,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"","keywords":"Solubility; Sequence (biology); Chemistry; Biochemistry; Organic chemistry","score_opus":0.020630593573197856,"score_gpt":0.25666773819293076,"score_spread":0.2360371446197329,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4291340499","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97398525,0.0014035717,0.023879582,0.00015802679,0.00008477378,0.00035621208,0.000058151767,0.000009158967,0.000065270004],"genre_scores_gemma":[0.999347,0.00005961521,0.00021480094,0.000031001848,0.00007747378,0.00004290856,0.00003791381,0.000011646944,0.00017769611],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99819916,0.00029703238,0.00030533288,0.00023725432,0.00028827845,0.00067294127],"domain_scores_gemma":[0.99932706,0.0000040275136,0.0002136365,0.00028706557,0.000117880765,0.00005034909],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0020543179,0.000098356926,0.00010999511,0.00004411595,0.0002803078,0.000010039132,0.00022966861,0.000057551002,0.000060502647],"category_scores_gemma":[0.000084491774,0.00010024074,0.00010747852,0.00009909844,0.000063457344,0.000005487429,0.00006480398,0.00069104944,6.261426e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022817284,0.00019124435,0.0035691038,0.000010489395,0.000051749274,6.009482e-7,0.000022366612,0.0013511264,0.98994863,0.000928906,0.000005854766,0.003691752],"study_design_scores_gemma":[0.003598224,0.0034444686,0.0025277962,0.00002062663,0.00008570558,0.0005311646,0.0023303395,0.0077947667,0.93983483,0.03353097,0.0057473877,0.0005536928],"about_ca_topic_score_codex":0.0000760307,"about_ca_topic_score_gemma":0.00007992614,"teacher_disagreement_score":0.050113775,"about_ca_system_score_codex":0.00057817047,"about_ca_system_score_gemma":0.0030161405,"threshold_uncertainty_score":0.5350504},"labels":[],"label_agreement":null},{"id":"W4296908455","doi":"10.1101/2022.09.19.508607","title":"Getting Smaller by Denaturation: Acid-Induced Compaction of Antibodies","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Japan Society for the Promotion of Science; National Institute of Advanced Industrial Science and Technology","keywords":"Denaturation (fissile materials); Radius of gyration; Chemistry; Intramolecular force; Globular protein; Biophysics; Size-exclusion chromatography; Ultracentrifuge; Crystallography; Biochemistry; Stereochemistry; Organic chemistry; Biology; Nuclear chemistry; Enzyme","score_opus":0.01564857499595774,"score_gpt":0.2437513699688164,"score_spread":0.22810279497285868,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4296908455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928948,0.0037154967,0.0015794185,0.0002516999,0.00060489663,0.0005498304,0.00027335045,0.00009761072,0.000032888027],"genre_scores_gemma":[0.9976448,0.00024890978,0.0016024897,0.00011547517,0.00018283799,0.00013576359,0.000009605096,0.000050592273,0.000009555349],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997999,0.00021423552,0.00048389434,0.0007488043,0.0002883093,0.00026575665],"domain_scores_gemma":[0.9979092,0.000013922466,0.000510226,0.0010730366,0.00038737018,0.00010623509],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005346581,0.00032011612,0.0003373962,0.00008394031,0.00018520236,0.000058748694,0.0004134118,0.00041254438,0.000064313615],"category_scores_gemma":[0.00025610812,0.0003627278,0.00015335828,0.00016597552,0.00008255293,0.000009486719,0.00043015918,0.00047559093,0.000004446416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043157586,0.000109775545,0.0035194687,0.00015722314,0.00009999805,0.0000012512255,0.0000061904416,0.000020593443,0.9953797,0.00006666126,0.0005914482,0.0000045559414],"study_design_scores_gemma":[0.0002461054,0.00006448025,0.038571656,0.000031470558,0.000031120428,1.0953058e-8,0.000008382057,0.00009250188,0.94868124,9.704323e-7,0.011892795,0.00037929855],"about_ca_topic_score_codex":0.000030075189,"about_ca_topic_score_gemma":0.0000021929027,"teacher_disagreement_score":0.04669847,"about_ca_system_score_codex":0.000094980955,"about_ca_system_score_gemma":0.0003275718,"threshold_uncertainty_score":0.99988246},"labels":[],"label_agreement":null},{"id":"W4303419070","doi":"10.1002/cjce.24703","title":"Performance of pseudo‐specific cryogel in lysozyme purification from chicken egg white","year":2022,"lang":"en","type":"article","venue":"The Canadian Journal of Chemical Engineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Chromatography; Thermogravimetric analysis; Polyacrylamide; Adsorption; Lysozyme; Egg white; Epichlorohydrin; Agarose; Glutaraldehyde; Chemistry; Fourier transform infrared spectroscopy; Differential scanning calorimetry; Nuclear chemistry; Materials science; Chemical engineering; Polymer chemistry; Organic chemistry; Biochemistry","score_opus":0.007164039667929504,"score_gpt":0.18206971381850467,"score_spread":0.17490567415057517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4303419070","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981437,0.0010389611,0.00013991463,0.00043481038,0.000087080596,0.00006205538,0.000022313532,0.0000014677453,0.000069696354],"genre_scores_gemma":[0.99944925,0.000014585408,0.0003720733,0.00003075093,0.00008176205,0.0000076064694,0.000018810193,0.00000853391,0.000016637821],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993713,0.000026645479,0.00026972592,0.000088940586,0.00011537595,0.00012803191],"domain_scores_gemma":[0.9995246,0.000010778527,0.000101906546,0.00020646049,0.000052277795,0.00010398256],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033020746,0.00006497568,0.00010326751,0.00005996381,0.000034417426,0.0000085598695,0.00031235392,0.000042878346,0.000065735796],"category_scores_gemma":[0.00006629764,0.000058962403,0.000052422653,0.0001218903,0.000040105926,0.0000048374095,0.000021690123,0.00023220922,4.31706e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003989864,0.000013560538,0.005411567,0.000008399956,0.000014832983,0.0000016789229,0.00021938575,0.013917103,0.97955537,0.000060520895,0.00009030962,0.0006673585],"study_design_scores_gemma":[0.00069689704,0.00011776055,0.032365136,0.00003057957,0.000013756221,0.000059742728,0.00008095928,0.010262984,0.93728983,0.00007812707,0.018766416,0.00023780773],"about_ca_topic_score_codex":0.00018374447,"about_ca_topic_score_gemma":0.00006072295,"teacher_disagreement_score":0.042265553,"about_ca_system_score_codex":0.00008625521,"about_ca_system_score_gemma":0.00020528211,"threshold_uncertainty_score":0.24044171},"labels":[],"label_agreement":null},{"id":"W4308499608","doi":"10.1016/j.ab.2022.114961","title":"Cutting-edge mass spectrometry strategy based on imaged capillary isoelectric focusing (icIEF) technology for characterizing charge heterogeneity of monoclonal antibody","year":2022,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Advanced Electrophoresis Solutions (Canada)","funders":"","keywords":"Isoelectric focusing; Chromatography; Chemistry; Mass spectrometry; Isoelectric point; Biopharmaceutical; Monoclonal antibody; Capillary electrophoresis; Antibody; Biochemistry; Biology","score_opus":0.01466434246892824,"score_gpt":0.2876600186503597,"score_spread":0.27299567618143145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308499608","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911155,0.0006539795,0.0063547045,0.0006729553,0.00004647434,0.00033709436,0.00026786356,0.000035955898,0.0005154726],"genre_scores_gemma":[0.99738026,0.000023279714,0.001257699,0.00026014782,0.00011814735,0.000081790145,0.0007443498,0.000028807588,0.000105546795],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99804133,0.00007370046,0.0004491598,0.00071912416,0.00026513112,0.0004515782],"domain_scores_gemma":[0.99880284,0.000044892313,0.00022418585,0.0006715232,0.00014341665,0.00011314308],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048206502,0.00025015764,0.00032376606,0.00015870207,0.00024271688,0.000020954274,0.00040393992,0.00022573958,0.00011573021],"category_scores_gemma":[0.00030829437,0.0002724857,0.00026303626,0.00051948987,0.00017356142,0.000004349505,0.0001223251,0.00032120867,0.0000023233792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025189726,0.0003057535,0.0033318626,0.00008515761,0.00006201573,0.000003821029,0.0000022401196,0.000021118502,0.9951398,0.000132722,0.00008266739,0.00058094395],"study_design_scores_gemma":[0.0006144505,0.0005578453,0.0006289132,0.000008361415,0.00003650314,0.000011921448,0.000029710598,0.005781025,0.9909008,0.000119274664,0.0010401154,0.00027105055],"about_ca_topic_score_codex":0.0000039989595,"about_ca_topic_score_gemma":1.9100649e-7,"teacher_disagreement_score":0.0062647318,"about_ca_system_score_codex":0.00009139898,"about_ca_system_score_gemma":0.00023682529,"threshold_uncertainty_score":0.99997276},"labels":[],"label_agreement":null},{"id":"W4309764770","doi":"10.1016/j.jpba.2022.115178","title":"Imaged capillary isoelectric focusing (icIEF) tandem high resolution mass spectrometry for charged heterogeneity of protein drugs in biopharmaceutical discovery","year":2022,"lang":"en","type":"article","venue":"Journal of Pharmaceutical and Biomedical Analysis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Advanced Electrophoresis Solutions (Canada)","funders":"","keywords":"Chemistry; Isoelectric focusing; Chromatography; Biopharmaceutical; Capillary electrophoresis; Mass spectrometry; Tandem mass spectrometry; Analytical Chemistry (journal)","score_opus":0.01683972433334361,"score_gpt":0.3052159574898217,"score_spread":0.2883762331564781,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309764770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9600234,0.0049361866,0.03280931,0.0017564283,0.00007569534,0.00030098733,0.00008703484,0.0000038205185,0.000007139838],"genre_scores_gemma":[0.9969116,0.0004737631,0.002156997,0.0001639464,0.00016681722,0.000026785694,0.000062334715,0.000009765242,0.000027979517],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975241,0.0004296348,0.0008348748,0.0003329615,0.0005488972,0.00032955947],"domain_scores_gemma":[0.9990545,0.00006988041,0.00034087428,0.00015740427,0.00013419171,0.00024317401],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0020722863,0.00016340088,0.000492108,0.00051311345,0.00014345295,0.000023033908,0.00023925929,0.000113493625,0.00009076563],"category_scores_gemma":[0.00024668608,0.00013363897,0.0004012463,0.0013142846,0.0002700581,0.000018749159,0.00012680254,0.00040577623,1.8932776e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010962622,0.00062469236,0.004934098,0.00006878489,0.0005523977,0.000008499439,0.000025212837,0.00002561411,0.9895286,0.00009905406,0.000032596752,0.0030042033],"study_design_scores_gemma":[0.005754082,0.0018193495,0.01700512,0.000023629309,0.0013909917,0.00006204062,0.00022339748,0.012053129,0.95146066,0.001080934,0.00865903,0.00046761462],"about_ca_topic_score_codex":0.000013541417,"about_ca_topic_score_gemma":0.000002534771,"teacher_disagreement_score":0.038067903,"about_ca_system_score_codex":0.0000955546,"about_ca_system_score_gemma":0.00013862755,"threshold_uncertainty_score":0.5449639},"labels":[],"label_agreement":null},{"id":"W4310493721","doi":"10.1111/vox.13388","title":"<scp>PlasmaCap EBA</scp>: An innovative method of isolating plasma proteins from human plasma","year":2022,"lang":"en","type":"article","venue":"Vox Sanguinis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Interface Biologics (Canada)","funders":"","keywords":"Chromatography; Yield (engineering); SCALE-UP; Scalability; Elution; Fractionation; Chemistry; Biomedical engineering; Materials science; Computer science; Medicine","score_opus":0.02163510462272585,"score_gpt":0.30143359268493075,"score_spread":0.2797984880622049,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310493721","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98871034,0.00012245795,0.003658454,0.000056421148,0.00014443141,0.00057089544,0.00055754057,0.000040291052,0.0061391913],"genre_scores_gemma":[0.96867,0.0000027900599,0.029564233,0.00013148479,0.00013665586,0.00026688926,0.00062955456,0.00003535828,0.0005630015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99786323,0.00045518327,0.0005054556,0.0006071799,0.00028956338,0.0002793602],"domain_scores_gemma":[0.9985454,0.00007872449,0.00036689715,0.00070180057,0.00021235259,0.00009483783],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006571726,0.00021269263,0.00026405804,0.00008876057,0.00033015915,0.000021701677,0.00045795654,0.00014290484,0.00019964774],"category_scores_gemma":[0.00054969924,0.00022835056,0.00009637307,0.00037689632,0.00010479668,0.000009318495,0.00032135044,0.00028006345,0.000005201514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000505044,0.00026666734,0.0033224362,0.000018889157,0.0000845376,0.000002540135,0.0015757653,0.000080506186,0.9867126,0.0007755107,0.0008796427,0.0062303995],"study_design_scores_gemma":[0.0009032558,0.00082023087,0.0035507435,0.000006355277,0.000016577984,0.0000057441293,0.0021446499,0.0009102196,0.9012689,0.0005202208,0.08969929,0.00015382485],"about_ca_topic_score_codex":0.00027486778,"about_ca_topic_score_gemma":0.00014941243,"teacher_disagreement_score":0.08881965,"about_ca_system_score_codex":0.000034480334,"about_ca_system_score_gemma":0.00013581583,"threshold_uncertainty_score":0.93118656},"labels":[],"label_agreement":null},{"id":"W4311186292","doi":"10.3390/pr10122566","title":"A New Approach for Increasing Speed, Loading Capacity, Resolution, and Scalability of Preparative Size-Exclusion Chromatography of Proteins","year":2022,"lang":"en","type":"article","venue":"Processes","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Cuboid; Volumetric flow rate; Resolution (logic); Pressure drop; Volume (thermodynamics); Chromatography; Chemistry; Flow (mathematics); Packed bed; Analytical Chemistry (journal); Materials science; Mechanics; Computer science; Geometry; Mathematics; Physics; Thermodynamics","score_opus":0.020090615902280524,"score_gpt":0.2651060757432171,"score_spread":0.24501545984093656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311186292","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96918184,0.002434909,0.02667624,0.000056591958,0.000011068386,0.0010601039,0.00009172816,0.000010247705,0.00047724918],"genre_scores_gemma":[0.9680609,0.00004839318,0.031663705,0.000011019311,0.000020061452,0.00011974417,0.00003755174,0.000007063892,0.000031567768],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990909,0.00011252021,0.00024202093,0.00031253707,0.00013455572,0.000107438784],"domain_scores_gemma":[0.999262,0.00005099344,0.0001891476,0.00021527518,0.0002362974,0.000046320194],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006119765,0.00008776694,0.00015642802,0.000033902463,0.00015843702,0.0000072629164,0.00012957679,0.000047347796,0.000014839801],"category_scores_gemma":[0.0011448164,0.0000867452,0.000048439953,0.00023383278,0.00013896568,0.000007336848,0.00016306166,0.000048852624,3.5028112e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012264253,0.00052104075,0.028543437,0.0036550006,0.00006424211,4.9384017e-8,0.0013307303,0.000113559254,0.9628258,0.00029448466,0.0001283827,0.0012968617],"study_design_scores_gemma":[0.00077836146,0.00049062836,0.0055160485,0.000022953023,0.000027522927,0.000011672395,0.00052146724,0.00039419578,0.98658615,0.0027760246,0.0027012764,0.00017370691],"about_ca_topic_score_codex":0.00011717812,"about_ca_topic_score_gemma":0.000012468647,"teacher_disagreement_score":0.023760356,"about_ca_system_score_codex":0.000013253633,"about_ca_system_score_gemma":0.0002175059,"threshold_uncertainty_score":0.35373667},"labels":[],"label_agreement":null},{"id":"W4311616591","doi":"10.3390/pharmaceutics14122809","title":"Potential of Nuclear Imaging Techniques to Study the Oral Delivery of Peptides","year":2022,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"H. Lundbeck A/S; Novo Nordisk Fonden; Science and Engineering Research Board; Novo Nordisk; Lundbeckfonden","keywords":"Nuclear imaging; Peptide; Molecular imaging; Medicine; Chemistry; Nanotechnology; Biochemistry; Materials science; Biology; Nuclear medicine; Biotechnology; In vivo","score_opus":0.08110147328087358,"score_gpt":0.40236139368608764,"score_spread":0.32125992040521406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311616591","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0016239551,0.9963828,0.00007053416,0.000040313484,0.00009321615,0.0014470974,0.00011738488,0.0000144044525,0.00021033516],"genre_scores_gemma":[0.039603107,0.9595876,0.00044640063,0.00011195603,0.000051665695,0.00010069931,0.000044021774,0.000030446487,0.000024118004],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998667,0.00035047746,0.0004227672,0.00025564453,0.00017981204,0.00012427651],"domain_scores_gemma":[0.9991109,0.000018888788,0.0002473996,0.00050132273,0.000079031466,0.00004250056],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00060112093,0.00016647954,0.00039562982,0.000049120314,0.000075623284,0.000009046611,0.00052635185,0.00005095335,0.000108384564],"category_scores_gemma":[0.00005459942,0.0001268103,0.0002356013,0.0001409658,0.00008050532,0.0000016614363,0.0004464169,0.00019045503,0.0000019178985],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002635037,0.00026203453,0.00002421521,0.0007955587,0.00015942063,0.0000015870273,0.00007508121,0.0000010430613,0.0031191811,0.000010820677,0.0001998608,0.99532485],"study_design_scores_gemma":[0.00008116381,0.000094203526,0.000008977399,0.000048560414,0.00036671068,0.000006821314,0.00016679482,0.0000068205077,0.003621562,0.0000055004525,0.99547046,0.0001224186],"about_ca_topic_score_codex":0.000012410024,"about_ca_topic_score_gemma":9.657721e-7,"teacher_disagreement_score":0.9952706,"about_ca_system_score_codex":0.000019149269,"about_ca_system_score_gemma":0.00009738247,"threshold_uncertainty_score":0.5171173},"labels":[],"label_agreement":null},{"id":"W4312020029","doi":"10.1039/d2ay01670b","title":"Fractionation and online mass spectrometry based on imaged capillary isoelectric focusing (icIEF) for characterizing charge heterogeneity of therapeutic antibody","year":2022,"lang":"en","type":"article","venue":"Analytical Methods","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Advanced Electrophoresis Solutions (Canada)","funders":"","keywords":"Isoelectric focusing; Chemistry; Chromatography; Fractionation; Mass spectrometry; Analytical Chemistry (journal); Tandem mass spectrometry; Isoelectric point; Capillary electrophoresis; Capillary electrophoresis–mass spectrometry; Capillary action; Electrospray ionization; Materials science; Biochemistry","score_opus":0.038763138551742064,"score_gpt":0.3925377638752549,"score_spread":0.35377462532351284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312020029","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4767951,0.00055312825,0.52143794,0.0007025632,0.00005822342,0.00029460766,0.00007306456,0.000009981662,0.000075368174],"genre_scores_gemma":[0.9296177,0.00004795435,0.069364965,0.0005744437,0.00006697355,0.000030783496,0.000253942,0.000014246602,0.000028991286],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986435,0.00046103014,0.00024401046,0.00033610006,0.00014914005,0.00016619124],"domain_scores_gemma":[0.9993214,0.0001625647,0.00012499877,0.00025764396,0.000082333405,0.00005107381],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011897766,0.000110573805,0.00019045685,0.00011947609,0.0001573905,0.000012092155,0.000097040545,0.000064931606,0.000050685172],"category_scores_gemma":[0.00036318827,0.00010931509,0.00011433778,0.00023574423,0.000050478073,0.000004914731,0.000034524037,0.00014166777,2.2157786e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019029937,0.0001941897,0.0014801093,0.000026460086,0.00004054291,2.6190847e-7,0.0000051408524,0.000016448494,0.9879927,0.0003111888,0.0000041322683,0.009738522],"study_design_scores_gemma":[0.0006467096,0.0008345521,0.029708443,0.000003984947,0.00006371921,0.0000044631925,0.00002338999,0.088408075,0.8751034,0.000503377,0.0045052194,0.00019465813],"about_ca_topic_score_codex":0.0000041883595,"about_ca_topic_score_gemma":4.0883245e-7,"teacher_disagreement_score":0.4528226,"about_ca_system_score_codex":0.000037149362,"about_ca_system_score_gemma":0.00005303329,"threshold_uncertainty_score":0.44577402},"labels":[],"label_agreement":null},{"id":"W4312083942","doi":"10.1016/j.jchromb.2022.123579","title":"A fast, efficient, and scalable method for purifying recombinant SARS-CoV-2 spike protein","year":2022,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; National Research Council Canada; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; McMaster University","keywords":"Chemistry; Chromatography; Recombinant DNA; Affinity chromatography; Membrane; Elution; Downstream processing; Protein purification; Biopharmaceutical; Size-exclusion chromatography; Myc-tag; Biochemistry; Enzyme; Fusion protein; Biology","score_opus":0.016952763135997008,"score_gpt":0.2935395168738592,"score_spread":0.2765867537378622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312083942","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9480263,0.0030058182,0.04761642,0.00043577122,0.00017024041,0.00055441685,0.000022518601,0.000006934879,0.00016155496],"genre_scores_gemma":[0.9670651,0.000037526952,0.03250555,0.00014909267,0.000062839725,0.0001075181,0.0000073835918,0.00001668869,0.000048282625],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998898,0.00016316478,0.000369346,0.00020515863,0.00018151855,0.00018275631],"domain_scores_gemma":[0.9992548,0.00001660485,0.00033602436,0.00020117809,0.00013400323,0.000057348643],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012194996,0.000110377514,0.00020079438,0.00013402772,0.00022254419,0.000031325973,0.00019282445,0.00005370508,0.000008861729],"category_scores_gemma":[0.00008051281,0.00009944597,0.00022832748,0.00018743274,0.000051818115,0.000004931486,0.000084862564,0.00014587707,1.9037425e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026230345,0.00021406348,0.0005958958,0.00006346256,0.00006628727,0.000002668996,0.00005759047,0.000034773097,0.99156445,0.00026965962,0.00086350983,0.0060053417],"study_design_scores_gemma":[0.001919457,0.001579437,0.0012359921,0.000029038536,0.000041686468,0.0003006384,0.0002257542,0.0007185379,0.8165451,0.0014526527,0.1757174,0.00023425037],"about_ca_topic_score_codex":0.000005359202,"about_ca_topic_score_gemma":0.0000016514778,"teacher_disagreement_score":0.1750193,"about_ca_system_score_codex":0.0000142973695,"about_ca_system_score_gemma":0.00008330271,"threshold_uncertainty_score":0.4055289},"labels":[],"label_agreement":null},{"id":"W4312225178","doi":"10.1089/phage.2022.0035","title":"Purification of Functional Gene Transfer Agents Using Two-Step Preparative Monolithic Chromatography","year":2022,"lang":"en","type":"article","venue":"PHAGE","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Chromatography; Gene transfer; Chemistry; Gene; Biochemistry","score_opus":0.03475710771271979,"score_gpt":0.28604628091284695,"score_spread":0.25128917320012717,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312225178","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9605258,0.0008629063,0.037529383,0.000032609514,0.00008453775,0.0003020968,0.00011049887,0.000010593659,0.00054155913],"genre_scores_gemma":[0.99865484,0.000016426902,0.0007751092,0.0000683837,0.000038161717,0.000111616246,0.00023126148,0.000009384479,0.000094837735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991118,0.00015378473,0.00019957233,0.00026291536,0.00016539123,0.00010656741],"domain_scores_gemma":[0.9995477,0.000004938139,0.000056158322,0.00028938334,0.00006449683,0.00003732558],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023285723,0.00008267925,0.00008849507,0.000044013217,0.00014120601,0.0000058492765,0.000116270414,0.000034161883,0.0002379883],"category_scores_gemma":[0.000013340798,0.00009030815,0.00009419219,0.00014173894,0.000059830727,0.00000449572,0.00004018353,0.0000679573,0.000001959509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000111033136,0.00018615174,0.001464013,0.000013464147,0.000050831568,4.2395135e-7,0.00014664818,0.001059499,0.9958842,0.00041567456,0.00007946172,0.000588592],"study_design_scores_gemma":[0.00091377576,0.000160745,0.026779663,0.0000021434296,0.000030434727,0.000014449736,0.00015416846,0.0038658439,0.95878303,0.00022003552,0.008893305,0.0001824307],"about_ca_topic_score_codex":0.00002665363,"about_ca_topic_score_gemma":0.0000035964156,"teacher_disagreement_score":0.038129006,"about_ca_system_score_codex":0.000020275704,"about_ca_system_score_gemma":0.00006642529,"threshold_uncertainty_score":0.36826596},"labels":[],"label_agreement":null},{"id":"W4313573630","doi":"10.1002/cjce.24827","title":"Feasibility of reactive chromatography for the production of 2‐phenyl ethyl acetate","year":2023,"lang":"en","type":"article","venue":"The Canadian Journal of Chemical Engineering","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Reactive distillation; Adsorption; Ethyl acetate; Catalysis; Acetic acid; Kinetics; Chromatography; Work (physics); Batch reactor; Particle size; Langmuir; Chemical engineering; Organic chemistry; Thermodynamics; Physical chemistry","score_opus":0.01895229101429283,"score_gpt":0.2437372798850419,"score_spread":0.22478498887074908,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313573630","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99743724,0.00057065283,0.00068222,0.000958309,0.00013427285,0.00018598523,0.000015030455,0.0000024319631,0.000013839895],"genre_scores_gemma":[0.99967206,0.000011246384,0.00020217997,0.000008914904,0.00007983984,0.0000069961716,0.0000037082798,0.0000063050143,0.000008743756],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995304,0.000015006817,0.00020635188,0.00007015492,0.00007229708,0.00010579814],"domain_scores_gemma":[0.99937075,0.000049466453,0.00011860639,0.00020392064,0.00018756672,0.000069675814],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005993435,0.000053026124,0.000098566015,0.00003770433,0.000029917554,0.0000042600227,0.00018232074,0.000047964357,0.0000020682355],"category_scores_gemma":[0.00091938407,0.00003434258,0.00011304141,0.00015568949,0.000108715474,0.000003301324,0.000009228547,0.00009453446,9.550506e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003594382,0.000005310302,0.00035684384,0.00003862479,0.000051683615,1.4231343e-7,0.00012142687,0.001436391,0.99728626,0.00009896167,0.00013726925,0.00043115806],"study_design_scores_gemma":[0.00012818602,0.000033284796,0.003020847,0.000018602937,0.000019859926,0.000008615569,0.00003960899,0.0004448593,0.9949959,0.0001733518,0.0010745308,0.000042334643],"about_ca_topic_score_codex":0.00010408955,"about_ca_topic_score_gemma":0.000069586604,"teacher_disagreement_score":0.002664003,"about_ca_system_score_codex":0.000020113406,"about_ca_system_score_gemma":0.00017114598,"threshold_uncertainty_score":0.14004497},"labels":[],"label_agreement":null},{"id":"W4318484507","doi":"10.1039/d2bm00819j","title":"Subcutaneous delivery of an antibody against SARS-CoV-2 from a supramolecular hydrogel depot","year":2023,"lang":"en","type":"article","venue":"Biomaterials Science","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Chemistry, Engineering and Medicine for Human Health, Stanford University; Stanford Maternal and Child Health Research Institute; Stanford Bio-X; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Bill and Melinda Gates Foundation; National Defense Science and Engineering Graduate; U.S. Department of Defense; National Institutes of Health; National Science Foundation","keywords":"Depot; Antibody; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Chemistry; Coronavirus disease 2019 (COVID-19); Supramolecular chemistry; 2019-20 coronavirus outbreak; Subcutaneous injection; Virology; Nanotechnology; Medicine; Immunology; Biology; Materials science; Bioinformatics; Pathology; Molecule; Organic chemistry","score_opus":0.02068828596533266,"score_gpt":0.3067891281867232,"score_spread":0.28610084222139054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318484507","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99890506,0.00013265121,0.00015535718,0.000030414418,0.00023815257,0.00020482676,0.00018580047,0.000053930147,0.0000938059],"genre_scores_gemma":[0.99857926,0.00006138332,0.00085942406,0.000101758495,0.000049462284,0.00001226669,0.0003187853,0.000011626119,0.000006006467],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985352,0.00007409009,0.00028988055,0.00054693077,0.00026854133,0.00028533695],"domain_scores_gemma":[0.99899983,0.000008110009,0.000116552364,0.0006728166,0.00012900175,0.00007369327],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00059276127,0.0001268324,0.00015751013,0.000084077576,0.000122066755,0.00006172623,0.00055983814,0.00009540862,0.0000073709025],"category_scores_gemma":[0.00014970789,0.00011997142,0.000052073345,0.00039539693,0.000521568,0.000014382827,0.00018742713,0.000013409711,0.000037500406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060191975,0.00005241292,0.00026063828,0.000009293648,0.000006372377,0.000016391918,0.00003415304,0.0000032301937,0.9987683,0.000025307025,0.0000135876835,0.00075008644],"study_design_scores_gemma":[0.00015688449,0.0001396269,0.0034347472,0.0000072453854,0.0000044927415,0.000009474805,0.000028417888,0.00029803166,0.9950252,0.00013951169,0.00060882827,0.00014751576],"about_ca_topic_score_codex":0.0002126177,"about_ca_topic_score_gemma":0.000021325694,"teacher_disagreement_score":0.0037431114,"about_ca_system_score_codex":0.000012848831,"about_ca_system_score_gemma":0.00018887596,"threshold_uncertainty_score":0.48922926},"labels":[],"label_agreement":null},{"id":"W4319019656","doi":"10.3390/membranes13020182","title":"Membrane-Based Hybrid Method for Purifying PEGylated Proteins","year":2023,"lang":"en","type":"article","venue":"Membranes","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; McMaster University","keywords":"Polyethylene glycol; Microfiltration; Chromatography; Membrane; PEG ratio; Micelle; Chemistry; Materials science; Lyotropic; Salt (chemistry); Chemical engineering; Polymer; Organic chemistry; Biochemistry","score_opus":0.026130211352516336,"score_gpt":0.3081071083703212,"score_spread":0.2819768970178048,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319019656","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81217927,0.0011527446,0.17287993,0.0056259222,0.00055033225,0.004702228,0.00034990694,0.0006531064,0.0019065706],"genre_scores_gemma":[0.9802996,0.000051615774,0.01526455,0.00041488814,0.00018987856,0.00092117913,0.0008095678,0.0000481359,0.002000578],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987493,0.000119741184,0.000232864,0.00045625668,0.00013595566,0.0003058705],"domain_scores_gemma":[0.99919313,0.000053295928,0.00007230886,0.0004737256,0.00012348751,0.00008406571],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072352856,0.00016102978,0.00016797405,0.00007376141,0.00016716802,0.000033447344,0.0002245268,0.00011082481,0.00004577902],"category_scores_gemma":[0.00039561908,0.0001516248,0.00015066,0.00019679971,0.00004762723,0.000003962931,0.00003935763,0.00006874389,0.00003758217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002105325,0.000051506137,0.00008901123,0.0003276384,0.000030812193,0.0000023476568,0.000023889894,0.000509561,0.990568,0.00010334053,0.00041919478,0.0076641785],"study_design_scores_gemma":[0.0006636236,0.00010021139,0.00019037865,0.000009723232,0.000012206002,0.0000035065618,0.000021822378,0.0068428633,0.848174,0.00015732432,0.14364457,0.00017977845],"about_ca_topic_score_codex":0.00001605643,"about_ca_topic_score_gemma":0.0000119064025,"teacher_disagreement_score":0.16812035,"about_ca_system_score_codex":0.000010019593,"about_ca_system_score_gemma":0.00010046854,"threshold_uncertainty_score":0.61830795},"labels":[],"label_agreement":null},{"id":"W4319596041","doi":"10.3390/pr11020508","title":"Research Progress on the Typical Variants of Simulated Moving Bed: From the Established Processes to the Advanced Technologies","year":2023,"lang":"en","type":"article","venue":"Processes","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Simulated moving bed; Separation (statistics); Component (thermodynamics); Process engineering; Process (computing); Computer science; Biochemical engineering; Separation process; Adsorption; Engineering; Chromatography; Chemistry; Machine learning","score_opus":0.04169951007346331,"score_gpt":0.3436475813931365,"score_spread":0.3019480713196732,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319596041","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96858937,0.004722353,0.00014081907,0.025000216,0.000049638482,0.0010906768,0.00006685176,0.00012025033,0.00021985297],"genre_scores_gemma":[0.9987293,0.00050608383,0.00009229485,0.00015173535,0.000049269536,0.0003232688,0.000034579756,0.000013800102,0.00009968607],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986948,0.00014967998,0.00019285352,0.0003667832,0.00032529244,0.00027059956],"domain_scores_gemma":[0.99779874,0.00065456977,0.000071360286,0.0007311755,0.00071888,0.00002526558],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.00087248645,0.00011327865,0.000105270155,0.00003889425,0.00033262573,0.000075858086,0.0009904748,0.000108150736,0.000011926748],"category_scores_gemma":[0.012589573,0.000052318388,0.000024286675,0.0014803418,0.0003481995,0.0000080844775,0.00032954797,0.00021613638,0.000022085997],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009198319,0.0026983898,0.06252242,0.0049613607,0.00090903946,0.000019793668,0.014169709,0.0073280074,0.42162776,0.0055740685,0.03721409,0.43377706],"study_design_scores_gemma":[0.00038519327,0.00043594543,0.015037132,0.00018499357,0.000017301269,0.0000011790744,0.008753189,0.00024923394,0.85422796,0.0057941526,0.11465049,0.00026323917],"about_ca_topic_score_codex":0.000017625978,"about_ca_topic_score_gemma":0.00008325343,"teacher_disagreement_score":0.43351382,"about_ca_system_score_codex":0.000008368638,"about_ca_system_score_gemma":0.00026882035,"threshold_uncertainty_score":0.9957278},"labels":[],"label_agreement":null},{"id":"W4319864351","doi":"10.5267/j.ccl.2022.11.001","title":"Studies of kinetic models and adsorption isotherms: application on the interaction of insulin with synthetic hydroxyapatite","year":2023,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Adsorption; Physisorption; Freundlich equation; Aqueous solution; Diffusion; Langmuir; Isoelectric point; Kinetics; Chromatography; Nuclear chemistry; Inorganic chemistry; Thermodynamics; Physical chemistry; Organic chemistry","score_opus":0.03281182519502197,"score_gpt":0.2867200413305544,"score_spread":0.25390821613553244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319864351","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99722224,0.00057937414,0.0012389828,0.00068935397,0.00002119245,0.0001870881,0.000011833742,0.000009597293,0.000040335606],"genre_scores_gemma":[0.9993172,0.00047046956,0.000020443109,0.000023263985,0.000025741472,0.00008590276,0.000044649925,0.000006968443,0.0000053380545],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99945945,0.000028273926,0.00015717607,0.00019172479,0.000094515024,0.00006883633],"domain_scores_gemma":[0.99949443,0.000028582324,0.00013428449,0.00027188024,0.00005416221,0.000016658489],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012920261,0.00008258405,0.00008963011,0.000015487598,0.000022196504,0.000003542972,0.00007965305,0.000030128958,0.0000029618484],"category_scores_gemma":[0.000052743595,0.000058188994,0.00002778289,0.00008868344,0.00016262205,0.0000034397058,0.000027756594,0.000060035465,0.0000012403817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000579348,0.000037044952,0.00017872403,0.00017398589,0.000024275865,3.030286e-8,0.00012160423,0.0010236298,0.9947229,0.000031212006,0.00004626955,0.0035823782],"study_design_scores_gemma":[0.00020036176,0.000020229609,0.0005566561,0.00009412772,0.000015850239,0.0000010310247,0.00018183856,0.0037687097,0.9945766,0.00013017125,0.00037160903,0.000082869046],"about_ca_topic_score_codex":0.0000017011893,"about_ca_topic_score_gemma":4.2531258e-7,"teacher_disagreement_score":0.003499509,"about_ca_system_score_codex":0.000010122592,"about_ca_system_score_gemma":0.0000085790025,"threshold_uncertainty_score":0.23728783},"labels":[],"label_agreement":null},{"id":"W4327682559","doi":"10.1007/s00249-023-01640-5","title":"A spectral decomposition quality assessment tool for multi-wavelength AUC experiments with UltraScan","year":2023,"lang":"en","type":"article","venue":"European Biophysics Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"National Institute of General Medical Sciences; National Institutes of Health; Canada Foundation for Innovation","keywords":"Computer science; Decomposition; Software; Suite; Visualization; Residual; Biological system; Chemistry; Algorithm; Data mining","score_opus":0.055621753728127325,"score_gpt":0.3642457642075298,"score_spread":0.30862401047940247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4327682559","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9257218,0.00003540287,0.07301889,0.00015397627,0.00013231521,0.00030040648,0.000052171363,0.00003320933,0.00055177714],"genre_scores_gemma":[0.9840633,0.000055837518,0.014866848,0.00010712626,0.00040460622,0.000018855804,0.00019656471,0.000031746622,0.00025508425],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987628,0.0002592987,0.00027474918,0.0002823947,0.00017211206,0.0002486556],"domain_scores_gemma":[0.99931365,0.000010707114,0.000165032,0.00027237288,0.00013615644,0.000102050675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00069354783,0.00014540763,0.000119682096,0.000032190805,0.00023770629,0.00008849953,0.00018077664,0.000030383559,0.000009527579],"category_scores_gemma":[0.000030023932,0.00012278034,0.00011975284,0.000100942714,0.00005659664,0.00001050661,0.000037808593,0.00013320541,0.000019098283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018436927,0.00026335582,0.0024071785,0.000016303742,0.00008386644,0.0000073101573,0.00012801556,0.00003759772,0.98806953,0.00033092566,0.00043168364,0.008039882],"study_design_scores_gemma":[0.004802628,0.0013475319,0.44495654,0.000041654766,0.000039952913,0.00007146843,0.00046441093,0.0011902441,0.53240716,0.0002739429,0.013663709,0.0007407395],"about_ca_topic_score_codex":0.0000016295785,"about_ca_topic_score_gemma":0.0000011883064,"teacher_disagreement_score":0.4556623,"about_ca_system_score_codex":0.00003836659,"about_ca_system_score_gemma":0.000079096666,"threshold_uncertainty_score":0.5006837},"labels":[],"label_agreement":null},{"id":"W4366822534","doi":"10.1021/acs.jpclett.3c00258","title":"Getting Smaller by Denaturation: Acid-Induced Compaction of Antibodies","year":2023,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry Letters","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Japan Society for the Promotion of Science; National Institute of Advanced Industrial Science and Technology","keywords":"Denaturation (fissile materials); Compaction; Chemistry; Process (computing); Biophysics; Antibody; Materials science; Computer science; Biology; Composite material; Immunology; Nuclear chemistry","score_opus":0.013240854397777812,"score_gpt":0.26442785499141686,"score_spread":0.251187000593639,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366822534","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965031,0.00011138244,0.00029005104,0.0029333031,0.000030383555,0.000040084367,0.0000051132088,0.0000070929764,0.00007948019],"genre_scores_gemma":[0.99949217,0.000020621763,0.00002694497,0.00013410598,0.00027640557,9.738204e-7,0.00001797636,0.00000618305,0.000024629946],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99940497,0.00005326088,0.0002007294,0.00007610555,0.0001652565,0.00009970996],"domain_scores_gemma":[0.99942595,0.000030977386,0.00024300527,0.00016851809,0.000095800526,0.000035746976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025679966,0.000077107776,0.00011860577,0.000008958594,0.000054634584,0.0000083500845,0.0001813679,0.000040525254,0.0000044067187],"category_scores_gemma":[0.000101424164,0.000053904954,0.00010040372,0.000085579406,0.000075342956,0.000006343634,0.00003107525,0.00014822588,0.0000020358545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000584054,0.000032761378,0.00007309184,0.000024762596,0.000039689057,4.6847055e-7,0.000100485726,0.000110799454,0.9964771,0.0000013421711,0.0028039608,0.00027709184],"study_design_scores_gemma":[0.00018272611,0.000028776385,0.0015073917,0.000010478324,0.00001648957,0.0000071080935,0.00011552967,0.0002273139,0.99724865,0.000015254323,0.000580713,0.00005954246],"about_ca_topic_score_codex":0.0000016795766,"about_ca_topic_score_gemma":1.473446e-7,"teacher_disagreement_score":0.0029890495,"about_ca_system_score_codex":0.00001157137,"about_ca_system_score_gemma":0.000021151232,"threshold_uncertainty_score":0.21981803},"labels":[],"label_agreement":null},{"id":"W4367043061","doi":"10.1016/j.chroma.2023.464030","title":"Optimization of fluid flow in membrane chromatography devices using computational fluid dynamic simulations","year":2023,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Computational fluid dynamics; Membrane; Chemistry; Chromatography; Flow (mathematics); Volumetric flow rate; Fluidics; Mechanics; Engineering; Physics","score_opus":0.012775423123523302,"score_gpt":0.2762653783425769,"score_spread":0.2634899552190536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4367043061","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95748925,0.0010183747,0.041045576,0.00008693272,0.00009370015,0.00017083538,0.00004752888,0.000012178842,0.00003563864],"genre_scores_gemma":[0.9799855,0.0001830013,0.019626584,0.00003169212,0.00003340343,0.0000029422627,0.00012045529,0.0000149222315,0.0000015116292],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9985765,0.00011838703,0.000699156,0.00016972914,0.0002779402,0.00015826823],"domain_scores_gemma":[0.9989735,0.000042387663,0.00040463652,0.00018927318,0.00032132072,0.00006889691],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040728797,0.00012862535,0.00024712604,0.0006678054,0.00006473304,0.000019973695,0.00018490275,0.00011543491,0.00002762183],"category_scores_gemma":[0.00007736329,0.00012649703,0.00024882075,0.0012109721,0.00010938942,0.000024641233,0.000031723164,0.00008310579,6.5058754e-7],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006057258,0.00011769875,0.012626062,0.00006906687,0.00008620104,0.0000029193427,0.00007842626,0.78984696,0.1968369,0.000025654983,0.000025889145,0.0002236326],"study_design_scores_gemma":[0.0015988273,0.00022577256,0.073828556,0.00014069039,0.000052159143,0.0000613919,0.00016768504,0.8986348,0.024219139,0.00047406138,0.00035054487,0.00024635487],"about_ca_topic_score_codex":0.0000069316307,"about_ca_topic_score_gemma":0.00001668434,"teacher_disagreement_score":0.17261776,"about_ca_system_score_codex":0.000013925235,"about_ca_system_score_gemma":0.00013332262,"threshold_uncertainty_score":0.51583993},"labels":[],"label_agreement":null},{"id":"W4367595612","doi":"10.1007/s11095-023-03528-7","title":"Analysis of the Adsorbed Vaccine Formulations Using Water Proton Nuclear Magnetic Resonance—Comparison with Optical Analytics","year":2023,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"Sanofi","keywords":"Adjuvant; Materials science; Adsorption; Laser; Chemistry; Analytical Chemistry (journal); Chromatography; Optics; Medicine; Immunology; Organic chemistry","score_opus":0.16023530380193282,"score_gpt":0.4599565278683611,"score_spread":0.2997212240664283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4367595612","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996717,0.00025739643,0.00043231808,0.0012297049,0.000014693491,0.00077214156,0.000016579052,0.000015274625,0.0005448932],"genre_scores_gemma":[0.9992654,0.000050458224,0.00029281687,0.000044981625,0.000030238456,0.00005018457,0.00003415328,0.000015288124,0.00021650443],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99815834,0.00025934272,0.00028121728,0.00032259178,0.0005512019,0.00042729953],"domain_scores_gemma":[0.9988857,0.00006519605,0.00002600207,0.0005464654,0.0003467774,0.0001298791],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001183964,0.00009510395,0.00018237923,0.0001798884,0.00019504895,0.000028558814,0.00032238924,0.000088614266,0.00014939468],"category_scores_gemma":[0.0003139879,0.000055737743,0.00011328104,0.0015722758,0.00022988064,0.000005012021,0.0002858752,0.0002886563,0.000016777483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001228128,0.0004579596,0.11743387,0.00011822584,0.00038089897,0.0000030777148,0.00030080666,0.0033805287,0.86488354,0.0014664193,0.00016285898,0.010183696],"study_design_scores_gemma":[0.000830006,0.0002734876,0.08722105,0.000014354196,0.0003042829,0.0000017141842,0.00009246639,0.40583166,0.430887,0.00014914996,0.07422621,0.00016860916],"about_ca_topic_score_codex":0.00001731365,"about_ca_topic_score_gemma":0.00002085554,"teacher_disagreement_score":0.4339965,"about_ca_system_score_codex":0.0000313706,"about_ca_system_score_gemma":0.00008215567,"threshold_uncertainty_score":0.22729191},"labels":[],"label_agreement":null},{"id":"W4376130188","doi":"10.1101/2023.05.11.540323","title":"Development and Biophysical Characterization of a Humanized FSH–Blocking Monoclonal Antibody Therapeutic Formulated at an Ultra–High Concentration","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Harrington Discovery Institute, University Hospitals; National Institutes of Health; York University","keywords":"Thermal stability; Differential scanning calorimetry; Chemistry; Dynamic light scattering; Fourier transform infrared spectroscopy; Chromatography; Materials science; Nanoparticle; Chemical engineering; Nanotechnology; Physics; Organic chemistry","score_opus":0.020244802720043,"score_gpt":0.24953007071992583,"score_spread":0.22928526799988283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376130188","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955251,0.00013144057,0.0032207114,0.00004232184,0.00018394251,0.0006661858,0.00014872421,0.00008069697,8.820274e-7],"genre_scores_gemma":[0.9981187,0.00015652094,0.0013170694,0.000050421815,0.00012260616,0.00009845623,0.000075722666,0.000056549827,0.000003978269],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982092,0.00011359517,0.00048567352,0.0007292933,0.00021120046,0.0002510825],"domain_scores_gemma":[0.9985807,0.000009750566,0.00038313668,0.00058995787,0.0003164313,0.00012001182],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034030958,0.00030075663,0.00031584737,0.000060388786,0.00022482048,0.00005849982,0.00022571198,0.00038677535,0.000008318627],"category_scores_gemma":[0.000046228113,0.00032143758,0.00006031259,0.00014412493,0.00010523508,0.000014489227,0.00025347536,0.00016703398,0.0000037722837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000098840654,0.00012070712,0.004594365,0.00014952893,0.000102349295,0.0000013812931,0.00003440635,0.0000065918734,0.99461085,0.00026536034,5.1670725e-7,0.000015116719],"study_design_scores_gemma":[0.00036241568,0.000048494,0.22381559,0.000048344133,0.000027600352,1.0764375e-8,0.0000015234405,0.0004145066,0.77457446,0.0000019425593,0.00043389702,0.00027118926],"about_ca_topic_score_codex":0.00001185769,"about_ca_topic_score_gemma":0.000002634468,"teacher_disagreement_score":0.22003636,"about_ca_system_score_codex":0.00007481162,"about_ca_system_score_gemma":0.00027901452,"threshold_uncertainty_score":0.99992377},"labels":[],"label_agreement":null},{"id":"W4381191076","doi":"10.7554/elife.88898","title":"Development and biophysical characterization of a humanized FSH–blocking monoclonal antibody therapeutic formulated at an ultra-high concentration","year":2023,"lang":"en","type":"article","venue":"eLife","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Institute on Aging; National Institutes of Health; York University","keywords":"Monoclonal antibody; Blocking (statistics); Humanized antibody; Chemistry; Antibody; Cell biology; Biology; Immunology; Computer science","score_opus":0.019942310670107363,"score_gpt":0.2817246602344569,"score_spread":0.26178234956434954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381191076","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987411,0.000030501064,0.0008985497,0.00004497787,0.000033079108,0.00019182448,0.000014007122,0.000023074244,0.000022914304],"genre_scores_gemma":[0.99783987,0.000047388778,0.00019528583,0.00007437215,0.000037712998,0.000014694291,0.0017375957,0.000007948819,0.000045107652],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99938434,0.00003754327,0.0001775331,0.00019124671,0.00010547906,0.00010387597],"domain_scores_gemma":[0.9996811,0.0000042911024,0.0000747893,0.0001289804,0.00006994212,0.000040866744],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013295737,0.00007357641,0.00008663296,0.000016766038,0.00013107894,0.000010253306,0.000055353492,0.000064389824,0.000009454323],"category_scores_gemma":[0.000015353522,0.00006987497,0.00001811838,0.00007974227,0.00003751911,0.0000065254553,0.00003332377,0.000025893045,0.0000035662868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006577446,0.000040473744,0.0023790796,0.000011677549,0.000017615077,2.1919637e-7,0.00031766784,0.0000017738517,0.99354154,0.00025558093,0.0000010369104,0.003367581],"study_design_scores_gemma":[0.0003267999,0.000050553932,0.12668973,0.000004216367,0.0000043399896,7.956214e-7,0.000019857896,0.0006264377,0.8707506,0.00001221351,0.0014393227,0.000075116994],"about_ca_topic_score_codex":0.0000029237892,"about_ca_topic_score_gemma":0.0000032291096,"teacher_disagreement_score":0.12431066,"about_ca_system_score_codex":0.000010913567,"about_ca_system_score_gemma":0.00003965136,"threshold_uncertainty_score":0.28494188},"labels":[],"label_agreement":null},{"id":"W4381598504","doi":"10.1038/s41598-023-35870-6","title":"A universal tool for stability predictions of biotherapeutics, vaccines and in vitro diagnostic products","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"Sanofi","keywords":"Computer science; Computational biology; Data science; Biology","score_opus":0.016907469824331642,"score_gpt":0.258759618381538,"score_spread":0.24185214855720635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381598504","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99773973,0.0002840566,0.0003481996,0.0002931696,0.0006185967,0.0006417265,0.000036064157,0.00001664043,0.000021787984],"genre_scores_gemma":[0.9991123,0.000028009583,0.00034059025,0.000005495818,0.000023757995,0.000054815322,0.00015641178,0.0000050851195,0.00027351695],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906904,0.00003253278,0.0002415528,0.00044627138,0.000086032174,0.00012455395],"domain_scores_gemma":[0.999206,0.00003805056,0.00008633077,0.0004720593,0.00016999825,0.00002758202],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009548841,0.00005819934,0.000084698404,0.00006763887,0.000069473295,0.000019897372,0.000049794307,0.000048449627,0.0000041566705],"category_scores_gemma":[0.0013715352,0.000055322602,0.000029324885,0.00029482978,0.00015156218,0.000005511394,0.000040503928,0.000024855532,3.7626543e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005471683,0.00007412285,0.033970907,0.00006998588,0.000008256874,0.0000019166885,0.00009731373,0.000016502323,0.9640885,0.000014122161,0.000423414,0.0011802574],"study_design_scores_gemma":[0.00020186833,0.000042437412,0.0590819,0.000006510467,0.000008185096,0.000006309974,0.00009368708,0.0002138997,0.91630965,0.0011243998,0.02282848,0.0000826919],"about_ca_topic_score_codex":0.000008015439,"about_ca_topic_score_gemma":0.000023117791,"teacher_disagreement_score":0.047778856,"about_ca_system_score_codex":0.000010673441,"about_ca_system_score_gemma":0.00012913132,"threshold_uncertainty_score":0.22559902},"labels":[],"label_agreement":null},{"id":"W4382364162","doi":"10.1016/j.xphs.2023.06.014","title":"Stability of Opened Durvalumab (IMFINZI) Vials. The Beginning of the End of Costly Product Wastage?","year":2023,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"","keywords":"Durvalumab; Vial; Chemistry; High-performance liquid chromatography; Chromatography; Medicine","score_opus":0.08174320181544403,"score_gpt":0.3757706378758187,"score_spread":0.2940274360603747,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382364162","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99463207,0.0009903149,0.000080255835,0.0035000697,0.0001988571,0.00022288504,0.000018137063,0.0000016720808,0.00035573292],"genre_scores_gemma":[0.99948436,0.00019395926,0.00017736724,0.000063266554,0.000055444638,0.0000023539103,5.482507e-7,0.0000026734635,0.000020046098],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99827087,0.00035246953,0.00054287986,0.00015604359,0.00052200933,0.0001557493],"domain_scores_gemma":[0.99878603,0.00011627767,0.000471743,0.00025874443,0.00030988824,0.000057302914],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004800448,0.000071898074,0.00018370688,0.000030655803,0.00010817302,0.00001141429,0.00074206805,0.000034199707,0.000070673304],"category_scores_gemma":[0.0013639497,0.000036313348,0.0001496769,0.000480879,0.0016315612,0.000012738856,0.00017602975,0.00013395952,4.959716e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010769069,0.00010325953,0.017521417,0.000050713414,0.000025710842,2.495766e-7,0.00017663522,0.00008009946,0.9756719,0.0002956975,0.00009898346,0.005867676],"study_design_scores_gemma":[0.00026826077,0.00016347041,0.036323424,0.000019442572,0.000022541375,0.00000576744,0.00030348613,0.00018741137,0.95757437,0.00037523315,0.004713866,0.000042741274],"about_ca_topic_score_codex":0.000011267805,"about_ca_topic_score_gemma":0.0000051852185,"teacher_disagreement_score":0.018802006,"about_ca_system_score_codex":0.000010788634,"about_ca_system_score_gemma":0.00032581983,"threshold_uncertainty_score":0.6011555},"labels":[],"label_agreement":null},{"id":"W4385302722","doi":"10.1007/s00249-023-01671-y","title":"Suitability of double-stranded DNA as a molecular standard for the validation of analytical ultracentrifugation instruments","year":2023,"lang":"en","type":"article","venue":"European Biophysics Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"National Institute of General Medical Sciences; Department of Mechanical Engineering, University of Texas at Austin; Canada Foundation for Innovation; National Institutes of Health; National Science Foundation","keywords":"DNA supercoil; Minicircle; Analytical Ultracentrifugation; Chemistry; DNA; Sedimentation; Ultracentrifuge; Analytical Chemistry (journal); Sedimentation coefficient; Chromatography; Biology; Biochemistry; DNA replication","score_opus":0.023817460325174535,"score_gpt":0.2926830467551651,"score_spread":0.2688655864299906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385302722","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9865291,0.000047661666,0.012179587,0.00030835002,0.00009300286,0.00032994378,0.000064160726,0.000007007861,0.00044116646],"genre_scores_gemma":[0.99948734,0.000079172896,0.0001894924,0.000018466137,0.000080626225,0.00000452297,0.000084424435,0.000012818845,0.000043106],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989105,0.00016979185,0.00037823038,0.00016345287,0.00023956876,0.00013847082],"domain_scores_gemma":[0.9990349,0.00002713499,0.00025012545,0.0002926466,0.00033978556,0.00005540426],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011729015,0.00008990816,0.00012264587,0.00003329146,0.000095323856,0.000025420162,0.00021310769,0.00003553431,0.000010359159],"category_scores_gemma":[0.00020271946,0.00006830263,0.00016920683,0.00018934355,0.00011888707,0.000008355558,0.00003743519,0.000086612796,0.0000042001875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009738441,0.00010804849,0.002363185,0.000043987915,0.00012180371,9.550996e-7,0.00011587309,0.0003004089,0.9859522,0.0013579048,0.0001058929,0.008555878],"study_design_scores_gemma":[0.0015150195,0.00029239096,0.008459108,0.000011565842,0.00004311628,0.00000448973,0.000106051964,0.00018928759,0.98593825,0.0010638204,0.0022951383,0.00008173489],"about_ca_topic_score_codex":0.0000015672433,"about_ca_topic_score_gemma":2.4622247e-7,"teacher_disagreement_score":0.01295825,"about_ca_system_score_codex":0.000014258192,"about_ca_system_score_gemma":0.00008916547,"threshold_uncertainty_score":0.27853003},"labels":[],"label_agreement":null},{"id":"W4386271771","doi":"10.1007/978-1-0716-3362-5_8","title":"Magnetic Nanoparticles for Protein Separation and Purification","year":2023,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Protein purification; Magnetic nanoparticles; Biomolecule; Chemistry; Extraction (chemistry); Nanoparticle; Chromatography; Bioavailability; Nanotechnology; Materials science; Biochemistry; Biology; Bioinformatics","score_opus":0.029036868727504158,"score_gpt":0.4015257267828081,"score_spread":0.37248885805530396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386271771","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5159118,0.0011725656,0.48130858,0.0005880177,0.000049336806,0.0008251134,0.000010843227,0.000026987094,0.00010673722],"genre_scores_gemma":[0.5113471,0.00008243109,0.48675182,0.0001582604,0.000035053643,0.0011209332,0.00018660816,0.00001897679,0.00029881904],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986342,0.000502041,0.00022426355,0.0003978854,0.000033833545,0.00020777137],"domain_scores_gemma":[0.99954003,0.000029224153,0.00005148974,0.00028672343,0.000052088228,0.00004046048],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012409808,0.00010064428,0.00011902758,0.000080419035,0.000047963764,0.000012813176,0.000103250175,0.00016575714,0.000004919113],"category_scores_gemma":[0.0006824269,0.00010045034,0.000039086808,0.0001896868,0.00010570617,0.000002382711,0.000053126245,0.000049201095,0.0000042113647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004312566,0.000019954156,0.0004963921,0.000017483706,0.0000047917174,3.381024e-7,0.00002435936,0.000009510692,0.9543048,0.005486165,0.00001557052,0.03957748],"study_design_scores_gemma":[0.0003895137,0.00024889925,0.0025361378,0.0000033132674,0.0000046184928,0.0000020136001,0.00002743505,0.0007581133,0.96054083,0.016783474,0.018580206,0.0001254556],"about_ca_topic_score_codex":0.000005075763,"about_ca_topic_score_gemma":0.000007779206,"teacher_disagreement_score":0.039452024,"about_ca_system_score_codex":0.000008577834,"about_ca_system_score_gemma":0.000029904304,"threshold_uncertainty_score":0.4096246},"labels":[],"label_agreement":null},{"id":"W4386476484","doi":"10.1016/j.ab.2023.115312","title":"Imaged capillary isoelectric focusing tandem high-resolution mass spectrometry using nano electrospray ionization (ESI) for protein heterogeneity characterization","year":2023,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Advanced Electrophoresis Solutions (Canada)","funders":"FedDev Ontario","keywords":"Chemistry; Electrospray ionization; Chromatography; Repeatability; Tandem mass spectrometry; Tandem; Isoelectric focusing; Electrospray; Mass spectrometry; Capillary electrophoresis; Analytical Chemistry (journal); Materials science; Biochemistry; Enzyme","score_opus":0.015318333931802552,"score_gpt":0.2669692562213237,"score_spread":0.2516509222895212,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386476484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8175821,0.00017889273,0.18124172,0.00025219226,0.000050543236,0.0005162019,0.000058795627,0.00008043889,0.0000391292],"genre_scores_gemma":[0.9930245,0.00006826768,0.0031989738,0.00008300256,0.00038780164,0.00007759879,0.0027352436,0.00004069928,0.00038387583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980176,0.000085479805,0.00041365856,0.0007169026,0.0002498883,0.0005164751],"domain_scores_gemma":[0.9989128,0.000016589187,0.00018209785,0.00048171956,0.0002677167,0.00013907948],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047312534,0.000254091,0.00023655823,0.00011272991,0.00029022485,0.00007809917,0.00020154835,0.00036369084,0.000021360078],"category_scores_gemma":[0.00056629913,0.000272896,0.00016708647,0.00085454463,0.00009770488,0.00001684914,0.000060556515,0.00013892828,0.000010800691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000904153,0.00006224189,0.0009274616,0.0000702189,0.000054622906,0.0000012300043,0.0000029488122,0.00002716886,0.99823606,0.000110789995,0.0000564779,0.00036039075],"study_design_scores_gemma":[0.00047096756,0.00011512903,0.0019807573,0.000014061498,0.000047624697,0.0000065841423,0.0000075645125,0.01242126,0.98397154,0.00024330746,0.0004104919,0.0003107034],"about_ca_topic_score_codex":0.0000075732796,"about_ca_topic_score_gemma":0.0000015689044,"teacher_disagreement_score":0.17804275,"about_ca_system_score_codex":0.00016363601,"about_ca_system_score_gemma":0.00019967547,"threshold_uncertainty_score":0.99997234},"labels":[],"label_agreement":null},{"id":"W4388019852","doi":"10.1016/j.xphs.2023.10.038","title":"Heat Inactivation of Host Cell–Derived Enzymes as a Control Strategy for Polysorbate Degradation","year":2023,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"","keywords":"Degradation (telecommunications); Polysorbate; Host (biology); Enzyme; Chemistry; Biochemistry; Pulmonary surfactant; Computer science; Biology","score_opus":0.06061876283777592,"score_gpt":0.3816226404221921,"score_spread":0.32100387758441623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388019852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906,0.000707121,0.006528836,0.0015313908,0.00012009702,0.0001951903,0.000013429518,0.00000415323,0.0002997921],"genre_scores_gemma":[0.99924827,0.00020481406,0.0002718571,0.0001234722,0.000075096985,0.000006457462,0.0000043933724,0.0000028539494,0.0000628087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991796,0.000079922844,0.0002818738,0.00011922916,0.0002036537,0.00013570685],"domain_scores_gemma":[0.999486,0.000071582006,0.00011490699,0.00005822781,0.00019287351,0.00007640172],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00093751634,0.000059803566,0.000110232286,0.00006040258,0.000082634826,0.000021859027,0.0001624426,0.000047929112,0.000025479094],"category_scores_gemma":[0.0002741203,0.000044921948,0.000079591955,0.00020101819,0.00016990853,0.000017537086,0.000014440315,0.00005630324,0.0000016402729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018628045,0.00005655881,0.0004995072,0.000016926995,0.000012165191,4.010265e-7,0.00001859965,0.0001577163,0.99463123,0.0003534804,0.00011595674,0.00395116],"study_design_scores_gemma":[0.0007855832,0.0005709908,0.0029039858,0.0000063014118,0.000015532762,0.000005701643,0.00018514722,0.002211673,0.9886187,0.00034263337,0.0042992127,0.0000545693],"about_ca_topic_score_codex":0.0000055529454,"about_ca_topic_score_gemma":0.0000013161398,"teacher_disagreement_score":0.008648256,"about_ca_system_score_codex":0.000011248285,"about_ca_system_score_gemma":0.00016322476,"threshold_uncertainty_score":0.18318638},"labels":[],"label_agreement":null},{"id":"W4390744557","doi":"10.1128/spectrum.03465-23","title":"Unveiling the structure-emulsifying function relationship of truncated recombinant forms of the SA01-OmpA protein opens up a new vista in bioemulsifiers","year":2024,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute for Genetic Engineering and Biotechnology","keywords":"Recombinant DNA; Structure function; Biology; Function (biology); Computational biology; Genetics; Gene; Physics","score_opus":0.01382085270850065,"score_gpt":0.24511940930778917,"score_spread":0.23129855659928852,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390744557","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993746,0.0017629298,0.0008961161,0.0021744086,0.00042847067,0.00080177054,0.000049807255,0.000013292275,0.00012723573],"genre_scores_gemma":[0.9989949,0.00001684777,0.000082915794,0.00007002264,0.000033152646,0.000013271617,0.00009153224,0.000013643968,0.00068370963],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987735,0.00019501479,0.00042630866,0.0003434026,0.00004519989,0.00021657323],"domain_scores_gemma":[0.9992553,0.000034574638,0.00014870941,0.00050086743,0.00003405324,0.000026505519],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039953255,0.0001444644,0.00017595374,0.00006904942,0.00009271914,0.000016001542,0.00031210732,0.00021442963,0.000050875526],"category_scores_gemma":[0.00016418756,0.00008615528,0.00011888864,0.00035633516,0.00023873783,0.0000069754274,0.00010267114,0.00026864858,0.0000037315754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016232206,0.000022391094,0.0032040267,0.000044797016,0.0000383513,2.20117e-7,0.00017161646,0.000033105276,0.9918934,0.0034815916,0.00020754838,0.0007406295],"study_design_scores_gemma":[0.00052281463,0.00017829325,0.026758038,0.00007295363,0.000024103749,0.000016489552,0.00019358916,0.00010171083,0.95351094,0.0064415396,0.012030217,0.00014931531],"about_ca_topic_score_codex":0.00011930872,"about_ca_topic_score_gemma":0.00048560146,"teacher_disagreement_score":0.038382463,"about_ca_system_score_codex":0.000044956058,"about_ca_system_score_gemma":0.00020219713,"threshold_uncertainty_score":0.35133106},"labels":[],"label_agreement":null},{"id":"W4391613735","doi":"10.1002/cpz1.974","title":"Methods for the Design and Analysis of Analytical Ultracentrifugation Experiments","year":2024,"lang":"en","type":"article","venue":"Current Protocols","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"National Institute of General Medical Sciences; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; University of Lethbridge; National Science Foundation","keywords":"Analytical Ultracentrifugation; Ultracentrifuge; Sedimentation; Chromatography; Computer science; Chemistry; Biology","score_opus":0.12146477070838585,"score_gpt":0.498812491643933,"score_spread":0.37734772093554714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391613735","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00091789936,0.003468647,0.9682333,0.00008671041,0.00003775383,0.02721269,0.000020023363,0.0000068673603,0.00001612337],"genre_scores_gemma":[0.51569825,0.0002787505,0.10349655,0.0000572186,0.0001928931,0.37966427,0.00026266577,0.000031539315,0.00031783545],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99933875,0.0001419625,0.00017413206,0.00021017717,0.00005617134,0.00007878542],"domain_scores_gemma":[0.99953526,0.00011573606,0.000038301558,0.00021778261,0.00006331318,0.000029629404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008196604,0.00006322305,0.00010095695,0.000042655916,0.0000394903,0.000033417007,0.00008863074,0.00004077401,0.000014137339],"category_scores_gemma":[0.00020492049,0.000041930554,0.000098600154,0.0001954478,0.000065544526,0.0000031130144,0.000021124477,0.000036063808,3.5278612e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003030136,0.00022837856,0.0015584991,0.00033362955,0.0010346302,6.7215495e-8,0.0002325446,0.00020694443,0.23668523,0.007271027,0.0006785106,0.7514675],"study_design_scores_gemma":[0.00032980708,0.00017202129,0.0028693373,0.000032516848,0.0003954812,4.236332e-7,0.000027045364,0.15295212,0.44385692,0.00047218232,0.39877066,0.00012149998],"about_ca_topic_score_codex":4.877802e-7,"about_ca_topic_score_gemma":1.3569871e-7,"teacher_disagreement_score":0.86473674,"about_ca_system_score_codex":0.000007170082,"about_ca_system_score_gemma":0.000042042415,"threshold_uncertainty_score":0.17098783},"labels":[],"label_agreement":null},{"id":"W4393934834","doi":"10.1021/acsmedchemlett.4c00054","title":"Fitting of <i>k</i><sub>inact</sub> and <i>K</i><sub>I</sub> Values from Endpoint Pre-incubation IC<sub>50</sub> Data","year":2024,"lang":"en","type":"article","venue":"ACS Medicinal Chemistry Letters","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Incubation; Incubation period; Chemistry; IC50; Enzyme; Biochemistry; In vitro","score_opus":0.012453040976702514,"score_gpt":0.2496488952977743,"score_spread":0.23719585432107176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393934834","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9863672,0.005869469,0.0039995066,0.0024728333,0.00027845908,0.00036736645,0.0003895458,0.00010992567,0.00014564187],"genre_scores_gemma":[0.9943331,0.0012841983,0.00022335528,0.0009789951,0.0009171394,0.00005466049,0.0021299035,0.00007136173,0.0000072849366],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966839,0.00013557852,0.0007824643,0.0013291113,0.00057951536,0.00048940815],"domain_scores_gemma":[0.9976759,0.00017387515,0.00030546408,0.001459913,0.00012747695,0.00025735],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00094186276,0.00045727874,0.00044200936,0.000054650947,0.00014949254,0.00008757734,0.00067530654,0.0003557782,0.000013068985],"category_scores_gemma":[0.00060068443,0.0004566841,0.00012860076,0.00020955861,0.0004832033,0.000053839132,0.00047311652,0.000499873,0.000010848877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016604233,0.00007375697,0.0004651681,0.00055460935,0.00015574944,0.000021943002,0.00023712867,0.000010537451,0.9826812,0.0000058274577,0.003317019,0.012310986],"study_design_scores_gemma":[0.0005803427,0.00006592141,0.0021518127,0.0002509231,0.00016739355,0.000037414233,0.00017980581,0.00034337147,0.9936144,0.00017855932,0.0020003023,0.00042976637],"about_ca_topic_score_codex":0.000038490703,"about_ca_topic_score_gemma":0.000012126957,"teacher_disagreement_score":0.01188122,"about_ca_system_score_codex":0.00007710592,"about_ca_system_score_gemma":0.00018055168,"threshold_uncertainty_score":0.99978846},"labels":[],"label_agreement":null},{"id":"W4393945376","doi":"10.20944/preprints202404.0265.v1","title":"Development of a Robust Freeze-drying Process for Long-Term Stability of rVSV-SARS-CoV-2 Vaccine","year":2024,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); Term (time); Virology; Process (computing); 2019-20 coronavirus outbreak; Biology; Medicine; Computer science; Physics; Infectious disease (medical specialty); Internal medicine","score_opus":0.17521325914208316,"score_gpt":0.3854433606444197,"score_spread":0.21023010150233654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393945376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99139154,0.0008189631,0.0049936073,0.00010273677,0.0002321141,0.001878171,0.00015425938,0.000040638315,0.00038797487],"genre_scores_gemma":[0.9963067,0.00004927547,0.0023768407,0.000019950829,0.00007258901,0.0007497701,0.00032598086,0.00004480282,0.000054073076],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99701685,0.00008595503,0.0011052691,0.0012370534,0.00026366743,0.0002912237],"domain_scores_gemma":[0.99719834,0.000023663408,0.0005322152,0.0015531365,0.0006260943,0.00006653779],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012262532,0.00036013417,0.0005530087,0.00008618556,0.000056854988,0.000011505625,0.0007283593,0.0004680087,0.00005692213],"category_scores_gemma":[0.0005224132,0.00036290282,0.00029734976,0.00011207111,0.00010220366,0.0000045320667,0.0017306368,0.0003608877,0.000013687533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025486454,0.0003377301,0.20372929,0.0052028648,0.00022955913,4.5410712e-7,0.0006861577,0.000046670968,0.7883779,0.00003296864,0.000005141078,0.0010964009],"study_design_scores_gemma":[0.00036679584,0.000028774282,0.0870248,0.00021612346,0.000059164016,0.0000013650408,0.000057648114,0.000051557454,0.9109088,0.00053504243,0.00045356486,0.00029634644],"about_ca_topic_score_codex":0.000022301818,"about_ca_topic_score_gemma":0.00015099281,"teacher_disagreement_score":0.122530915,"about_ca_system_score_codex":0.00007518187,"about_ca_system_score_gemma":0.00081011094,"threshold_uncertainty_score":0.9998823},"labels":[],"label_agreement":null},{"id":"W4399575826","doi":"10.3390/v16060942","title":"Development of Robust Freeze-Drying Process for Long-Term Stability of rVSV-SARS-CoV-2 Vaccine","year":2024,"lang":"en","type":"article","venue":"Viruses","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; McGill University","keywords":"Term (time); Virology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); Process (computing); Biology; Medicine; Physics; Computer science; Infectious disease (medical specialty); Internal medicine","score_opus":0.0933285528102407,"score_gpt":0.3525390909843665,"score_spread":0.25921053817412576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399575826","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98198915,0.001932718,0.015421011,0.000033262284,0.000073855656,0.0003925335,0.000074910786,0.000018514096,0.00006407743],"genre_scores_gemma":[0.99720323,0.000028961602,0.0025321157,0.00003968521,0.000034189525,0.00008950585,0.000050397935,0.000013222841,0.00000868981],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991067,0.000022168764,0.00035841402,0.00029059398,0.00009704721,0.0001250966],"domain_scores_gemma":[0.9994375,0.000019922001,0.000079230886,0.00028616175,0.00015502036,0.000022147895],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029691742,0.000104041865,0.00015079846,0.000033495788,0.000035989797,0.000011379993,0.00015696866,0.00008235278,0.000015619189],"category_scores_gemma":[0.00013916077,0.00009162779,0.00006593016,0.00009221529,0.000044145156,0.0000074771733,0.000048577887,0.00003936378,0.0000015119516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010331676,0.00011608113,0.013163072,0.00089335185,0.000048321297,1.7629024e-7,0.00019002786,0.0000035442931,0.98018503,0.0000635698,0.000034149965,0.0051993607],"study_design_scores_gemma":[0.00019748512,0.000060218023,0.006683418,0.000045377983,0.000012480043,6.45558e-7,0.000040191713,0.000031856263,0.9884689,0.00004689573,0.004313657,0.00009891385],"about_ca_topic_score_codex":0.0000071055824,"about_ca_topic_score_gemma":0.0001167007,"teacher_disagreement_score":0.0152141135,"about_ca_system_score_codex":0.000013907014,"about_ca_system_score_gemma":0.0002037226,"threshold_uncertainty_score":0.3736473},"labels":[],"label_agreement":null},{"id":"W4399921766","doi":"10.18280/mmep.110604","title":"Analysis of Non-commensurate Model of Diclofenac Concentration in the Plasma to Enhance Drug Delivery System","year":2024,"lang":"en","type":"article","venue":"Mathematical Modelling and Engineering Problems","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Diclofenac; Plasma concentration; Drug; Drug delivery; Pharmacology; Medicine; Chemistry","score_opus":0.012246134396605213,"score_gpt":0.23156348348303032,"score_spread":0.2193173490864251,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399921766","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.52387434,0.00021556974,0.47569132,0.00004142062,0.0000069818134,0.00010970215,0.000007429017,0.0000058075316,0.000047450012],"genre_scores_gemma":[0.9949238,0.00004446346,0.0049533984,0.000005642677,0.0000055784076,0.000039147915,0.000008822154,0.0000060081557,0.00001318577],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99937564,0.000016497477,0.0002686844,0.00015335332,0.000087705055,0.0000981283],"domain_scores_gemma":[0.99971104,0.000039693445,0.00002485727,0.00016505514,0.00003064884,0.000028690052],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004705084,0.00007305124,0.00015771699,0.000053584026,0.000011843752,0.0000145419035,0.00007812279,0.00004136186,5.350284e-7],"category_scores_gemma":[0.0000145434615,0.000054203894,0.000048778646,0.00020973357,0.000016645763,0.0000037143052,0.000016570792,0.000053601452,4.5251628e-7],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000060338216,0.000021158365,0.00001437629,0.00069277495,0.00005356823,1.3587427e-7,0.0009779853,0.9312334,0.06494517,0.0017991056,0.000002182762,0.00025412737],"study_design_scores_gemma":[0.0000310685,0.000016114325,0.000011227098,0.0001406367,0.00004750385,4.5732668e-7,0.000053653017,0.97435486,0.025111603,0.00016417512,0.00001351381,0.00005515966],"about_ca_topic_score_codex":0.0000092833525,"about_ca_topic_score_gemma":0.0000018434204,"teacher_disagreement_score":0.47104943,"about_ca_system_score_codex":0.000008206919,"about_ca_system_score_gemma":0.000012019937,"threshold_uncertainty_score":0.22103706},"labels":[],"label_agreement":null},{"id":"W4400037863","doi":"10.2139/ssrn.4872637","title":"Irreversible Serum Protein Interaction on Polyethersulfone Dialyzer Membrane","year":2024,"lang":"en","type":"preprint","venue":"SSRN Electronic Journal","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Membrane; Chromatography; Biochemistry","score_opus":0.010437809508974554,"score_gpt":0.26680904161396457,"score_spread":0.25637123210499,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400037863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9717197,0.013920766,0.0021874474,0.004761863,0.0015863073,0.0010130566,0.00006121659,0.00006736893,0.004682283],"genre_scores_gemma":[0.9871384,0.0028433655,0.000076059856,0.00012609494,0.0008939547,0.0000683443,0.00008419618,0.00005474085,0.008714854],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99735355,0.00021699964,0.00036983957,0.0006170706,0.00026597816,0.0011765498],"domain_scores_gemma":[0.9989713,0.000008051568,0.00023286062,0.00057019165,0.000114221264,0.00010341444],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0014431606,0.00032127957,0.00024162568,0.00013501458,0.00012502,0.00011649348,0.000413834,0.00045131476,0.00007857306],"category_scores_gemma":[0.00011463126,0.0002920511,0.00032146435,0.000093818286,0.000055018827,0.0000047788194,0.00033481698,0.004240661,0.00012100203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024451935,0.00087881327,0.00021379154,0.000550422,0.0026585304,0.000019568735,0.00033073904,0.0007627493,0.8266366,0.043266736,0.0014013516,0.120835505],"study_design_scores_gemma":[0.001879517,0.0021100356,0.00022380089,0.0005741121,0.00027325604,0.0004064734,0.0014374324,0.000261161,0.4939402,0.4037925,0.09345751,0.001644013],"about_ca_topic_score_codex":0.00004372537,"about_ca_topic_score_gemma":0.00023397923,"teacher_disagreement_score":0.36052576,"about_ca_system_score_codex":0.0006307944,"about_ca_system_score_gemma":0.0025302856,"threshold_uncertainty_score":0.99995315},"labels":[],"label_agreement":null},{"id":"W4400213051","doi":"10.1021/acs.molpharmaceut.4c00526","title":"Parameterization of Physiologically Based Biopharmaceutics Models: Workshop Summary Report","year":2024,"lang":"en","type":"review","venue":"Molecular Pharmaceutics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Health Canada; University of Alberta","funders":"Center for Drug Evaluation and Research; U.S. Food and Drug Administration; U.S. Department of Health and Human Services","keywords":"Biopharmaceutics; Physiologically based pharmacokinetic modelling; Pharmacology; Chemistry; Medicine; Computational biology; Computer science; Pharmacokinetics; Biology; Pharmacognosy; Biochemistry; In vitro; Biological activity","score_opus":0.1309659897101786,"score_gpt":0.4191665619610947,"score_spread":0.2882005722509161,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400213051","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000076634555,0.9749867,0.02245928,0.000047275993,0.00038303228,0.0012413128,0.00026064506,0.00006767956,0.00047746606],"genre_scores_gemma":[0.0020860587,0.991371,0.0025175023,0.00026233183,0.00012072121,0.000223306,0.0029893485,0.00012566094,0.0003041118],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99657404,0.00047124142,0.0011828064,0.001011946,0.00037074843,0.00038922994],"domain_scores_gemma":[0.99773604,0.00004167528,0.00058927917,0.0012084356,0.00023489245,0.00018965571],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00060978916,0.0006399663,0.0010663992,0.00016892892,0.000053446634,0.00005020309,0.00061915047,0.0007478964,0.000022437785],"category_scores_gemma":[0.00020620144,0.00054951734,0.00091901387,0.00052764884,0.00023171869,0.000005945244,0.00031579545,0.00055312715,0.00001725649],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012677709,0.00071750704,0.0000018784544,0.037070498,0.0013756424,0.00044130694,0.000022164057,0.0017835037,0.0616921,0.00045823556,0.0011495218,0.89516085],"study_design_scores_gemma":[0.00022064394,0.00006269784,1.142028e-7,0.0013335288,0.0015733524,0.000055467273,0.0000038653234,0.00485326,0.0151446825,0.00019957109,0.9759807,0.0005721002],"about_ca_topic_score_codex":0.0000011077263,"about_ca_topic_score_gemma":3.027897e-7,"teacher_disagreement_score":0.9748312,"about_ca_system_score_codex":0.000060155227,"about_ca_system_score_gemma":0.00059544446,"threshold_uncertainty_score":0.99969566},"labels":[],"label_agreement":null},{"id":"W4400229714","doi":"10.3390/vaccines12070733","title":"Determination of Deamidation in Adjuvanted Vaccine Antigens through Isoaspartic Acid Quantification","year":2024,"lang":"en","type":"article","venue":"Vaccines","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"Sanofi","keywords":"Deamidation; Immunogenicity; Antigen; Chemistry; Biochemistry; Biology; Immunology; Enzyme","score_opus":0.018565552567332076,"score_gpt":0.2986339577054897,"score_spread":0.28006840513815767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400229714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9516502,0.003781954,0.043434322,0.00052317197,0.0001518928,0.00026354386,0.000013202456,0.00002813674,0.00015360191],"genre_scores_gemma":[0.99799347,0.00037928557,0.0012097455,0.000023984447,0.000051487168,0.000033722106,0.0001881683,0.000010501198,0.000109611945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992025,0.00005724542,0.0002975267,0.0002681825,0.00007180438,0.00010273154],"domain_scores_gemma":[0.9995416,0.000013066044,0.000060693783,0.00027036495,0.00009728088,0.000017027916],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021201193,0.00008604254,0.00010130585,0.00007201364,0.000022016808,0.000016193759,0.00008967101,0.000084192594,0.00003139896],"category_scores_gemma":[0.00015731648,0.000079708014,0.000041959687,0.00025818349,0.0000102786735,0.000016057094,0.000021679767,0.0000440068,0.00001237792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000647543,0.00006691535,0.0070302906,0.00010055048,0.000007646763,6.4967566e-7,0.00012707565,0.000013257163,0.9695707,0.00066865043,0.000090686095,0.022258816],"study_design_scores_gemma":[0.0002770081,0.00007953494,0.083310194,0.000039116996,0.000010794686,0.0000037213106,0.000050967905,0.0045513795,0.9056332,0.00068499893,0.0052522337,0.00010684039],"about_ca_topic_score_codex":0.00002484426,"about_ca_topic_score_gemma":0.0001327519,"teacher_disagreement_score":0.0762799,"about_ca_system_score_codex":0.000011994022,"about_ca_system_score_gemma":0.000038959726,"threshold_uncertainty_score":0.32503983},"labels":[],"label_agreement":null},{"id":"W4400498779","doi":"10.26434/chemrxiv-2024-b76v4","title":"Re-engineering lysozyme solubility and activity through surfactant complexation","year":2024,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"China Scholarship Council; Queen's University","keywords":"Lysozyme; Chemistry; Lipophilicity; Solubility; Pulmonary surfactant; Zeta potential; Amphiphile; Dynamic light scattering; Micelle; Lysis; Chromatography; Aqueous solution; Organic chemistry; Chemical engineering; Biochemistry; Nanoparticle","score_opus":0.028271179873689063,"score_gpt":0.2767535366199685,"score_spread":0.24848235674627941,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400498779","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98958284,0.003078683,0.0045805727,0.0007548675,0.0003226859,0.00041794774,0.000033600154,0.00007694499,0.0011518735],"genre_scores_gemma":[0.9979807,0.00026088397,0.0011558126,0.00004255309,0.0001507838,0.00006765536,0.00016970429,0.000027437687,0.00014442934],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986665,0.000048591584,0.00021743572,0.00075779436,0.00011974319,0.00018990079],"domain_scores_gemma":[0.9990058,0.00001752771,0.0000922625,0.00073999475,0.0000751891,0.00006925338],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034347395,0.0002472101,0.00024081695,0.00002065614,0.00005200235,0.00007073941,0.00016451324,0.00038164994,0.000025527668],"category_scores_gemma":[0.00018399488,0.0002489822,0.00011515597,0.000054402823,0.00009115353,0.000003421827,0.0007378551,0.00041414707,0.0000082233955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008855656,0.0001471422,0.0018697577,0.0015868827,0.00018897689,0.0000029029925,0.00026654426,0.00026853633,0.9916234,0.0005052433,0.0006725494,0.0027795022],"study_design_scores_gemma":[0.00023398123,0.000049434024,0.020101786,0.00008205136,0.000057952606,0.000003615575,0.00003474654,0.0049993885,0.95414406,0.0057697506,0.013939215,0.0005840385],"about_ca_topic_score_codex":0.000051607294,"about_ca_topic_score_gemma":0.000028054637,"teacher_disagreement_score":0.037479363,"about_ca_system_score_codex":0.000047753765,"about_ca_system_score_gemma":0.00010145682,"threshold_uncertainty_score":0.99999624},"labels":[],"label_agreement":null},{"id":"W4400650039","doi":"10.1016/j.ab.2024.115617","title":"Using absorbance detection for hs-SV-AUC characterization of adeno-associated virus","year":2024,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Sudbury","funders":"","keywords":"Absorbance; Analytical Ultracentrifugation; Adeno-associated virus; Chromatography; Sedimentation; Chemistry; Ultracentrifuge; Biology; Biochemistry; Gene","score_opus":0.02329947946625706,"score_gpt":0.30063533631656614,"score_spread":0.2773358568503091,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400650039","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9670562,0.0004898183,0.03174474,0.000096365475,0.00008547951,0.00016386871,0.0001854098,0.000027031176,0.00015108271],"genre_scores_gemma":[0.99874157,0.000044269465,0.00015201527,0.000043335855,0.00013467904,0.000020591428,0.0003830981,0.000015028036,0.00046543605],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912953,0.000019612411,0.00025466297,0.0003403006,0.000102323465,0.00015356095],"domain_scores_gemma":[0.9994851,0.000016609414,0.00006869432,0.00023685231,0.00013475951,0.00005798157],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001857985,0.00011058354,0.00012638781,0.00002423948,0.000045684483,0.00002468762,0.00009975376,0.0002228979,0.000024519577],"category_scores_gemma":[0.00028407847,0.00011240357,0.00013087605,0.00015805598,0.000089590416,0.0000050226736,0.000028057108,0.000071775365,0.0000028750244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047152364,0.00005555632,0.00012089911,0.000119058706,0.00005646676,3.5745637e-7,0.0000066296157,0.0000026084492,0.997563,0.0000518702,0.000027976805,0.0019483935],"study_design_scores_gemma":[0.00013480545,0.00004905639,0.00060494256,0.000029223578,0.000043888464,0.000002427969,0.000007849814,0.010309796,0.9859266,0.0000886684,0.0026793636,0.0001233545],"about_ca_topic_score_codex":0.000006665131,"about_ca_topic_score_gemma":0.0000023209386,"teacher_disagreement_score":0.03168534,"about_ca_system_score_codex":0.000042477695,"about_ca_system_score_gemma":0.00008571091,"threshold_uncertainty_score":0.45836845},"labels":[],"label_agreement":null},{"id":"W4400943057","doi":"10.1016/j.ejpb.2024.114425","title":"Development of an ELISA-based device to quantify antibody adsorption directly on medical plastic surfaces","year":2024,"lang":"en","type":"article","venue":"European Journal of Pharmaceutics and Biopharmaceutics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute for Biodiversity, Ecosystem Science, and Sustainability; Association Nationale de la Recherche et de la Technologie; Agence Nationale de la Recherche","keywords":"Adsorption; Monoclonal antibody; Polypropylene; Saturation (graph theory); Solid surface; Medical device; Materials science; Polymer; Chromatography; Polyethylene; Chemical engineering; Nanotechnology; Chemistry; Antibody; Biomedical engineering; Organic chemistry; Composite material; Engineering; Medicine","score_opus":0.055162488780665354,"score_gpt":0.38303483593796456,"score_spread":0.3278723471572992,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400943057","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876529,0.004217591,0.006716745,0.00043716448,0.0006178897,0.00015733237,0.000033359403,0.000016731514,0.00015029815],"genre_scores_gemma":[0.9923059,0.00086832454,0.0058969753,0.0006075914,0.00023731029,0.000001138984,0.000030582876,0.000033552016,0.00001864742],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977894,0.00046017312,0.0007732499,0.00029822843,0.00044964516,0.00022930812],"domain_scores_gemma":[0.99879366,0.00010054519,0.00020889656,0.00017449271,0.00022875723,0.0004936676],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0029701474,0.0002089067,0.00022538315,0.00016455921,0.00007383031,0.00005215362,0.000316702,0.00006653868,0.000042582917],"category_scores_gemma":[0.00029949672,0.00017175234,0.00008876567,0.00020230006,0.00010798623,0.000013165166,0.00007934177,0.00031576047,0.000014527181],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048348462,0.0002791482,0.000521703,0.00021838752,0.00010548734,0.000050588373,0.00024361399,0.0003374392,0.9241568,0.00005074789,0.000041742118,0.07351087],"study_design_scores_gemma":[0.0008916415,0.00048235207,0.003375712,0.0002200283,0.000073990894,0.00004341169,0.000074674324,0.0102564,0.7342511,0.0000033073038,0.250096,0.00023143673],"about_ca_topic_score_codex":3.8824962e-7,"about_ca_topic_score_gemma":0.0000017471797,"teacher_disagreement_score":0.25005424,"about_ca_system_score_codex":0.000022694161,"about_ca_system_score_gemma":0.0003081277,"threshold_uncertainty_score":0.70038575},"labels":[],"label_agreement":null},{"id":"W4402022715","doi":"10.1016/j.exphem.2024.104491","title":"3171 – IDENTIFYING STRESS GRANULES AS DETERMINANTS OF LEUKEMIA STEM CELL MAINTENANCE AND STRESS ADAPTATION","year":2024,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; McMaster University; University of Toronto; University Health Network","funders":"","keywords":"Adaptation (eye); Stress (linguistics); Stem cell; Leukemia; Computational biology; Biology; Cell biology; Neuroscience; Immunology; Philosophy","score_opus":0.017261747383527017,"score_gpt":0.29537144071362753,"score_spread":0.2781096933301005,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402022715","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9592957,0.039085843,0.00073845556,0.000017447219,0.00017246285,0.00019066826,0.00005971723,0.000017377639,0.00042236166],"genre_scores_gemma":[0.9990513,0.00016401862,0.0003121336,0.00001867515,0.000019567791,0.000049497296,0.000044115663,0.000013425059,0.00032728483],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991171,0.000060708247,0.00024560848,0.00034268064,0.00008035218,0.00015359504],"domain_scores_gemma":[0.9996326,0.000016076792,0.00006823441,0.00020374637,0.000029207291,0.000050140734],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000080234706,0.00011886638,0.00016038188,0.000035928213,0.000048386228,0.000020597769,0.000106087944,0.00011280162,0.000021118936],"category_scores_gemma":[0.000007710523,0.00011300925,0.000048730268,0.00004386554,0.00015113495,0.000009192404,0.00008213162,0.000054729735,0.000008294037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022489183,0.00024196653,0.013710482,0.0010566312,0.00004843914,0.000058584934,0.0025421162,0.000012981215,0.9537587,0.017071135,0.00017602414,0.01109803],"study_design_scores_gemma":[0.00023685976,0.00011472303,0.0005768859,0.000071415445,0.000005619906,0.000062685096,0.0029270325,0.00051410566,0.99478805,0.00011909146,0.00047265843,0.000110859495],"about_ca_topic_score_codex":0.00004392602,"about_ca_topic_score_gemma":0.00003475133,"teacher_disagreement_score":0.041029345,"about_ca_system_score_codex":0.000023381575,"about_ca_system_score_gemma":0.000059128073,"threshold_uncertainty_score":0.46083835},"labels":[],"label_agreement":null},{"id":"W4404206481","doi":"10.1016/j.chroma.2024.465513","title":"Chromatographic properties of deamidated peptides with Asn-Gly sequences in proteomic bottom-up experiments","year":2024,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research Manitoba; University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Chromatography","score_opus":0.014226997766422491,"score_gpt":0.25118129592923083,"score_spread":0.23695429816280833,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404206481","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9844502,0.014692818,0.00019223607,0.000098313285,0.00011511447,0.0003189549,0.0000067097153,0.000013399883,0.000112251735],"genre_scores_gemma":[0.9983073,0.00048336078,0.0010707118,0.000019099161,0.000043063377,0.000038190603,0.000004441245,0.000017406834,0.000016448945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99863756,0.00011592987,0.0005668674,0.00022266063,0.00027492727,0.00018207962],"domain_scores_gemma":[0.99926084,0.000006353535,0.00025390196,0.00023117213,0.00017370615,0.00007402205],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042515906,0.00016779889,0.0002714928,0.00037050244,0.000033850523,0.000048909187,0.0002513026,0.000110592046,0.000010604229],"category_scores_gemma":[0.000032726046,0.00011487142,0.00019905716,0.0005482326,0.00028980128,0.000029124261,0.000026459145,0.0001760423,8.587134e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026555435,0.00013470121,0.025445106,0.0002463845,0.00019188304,0.000016242837,0.0003237073,0.000008272544,0.9729252,0.00008783028,0.000052844956,0.00030230527],"study_design_scores_gemma":[0.00065767457,0.0007167808,0.017089423,0.00070471066,0.000027150747,0.00018485557,0.00033767367,0.000032089385,0.9788557,0.00014882565,0.0010738547,0.00017120449],"about_ca_topic_score_codex":0.000024700423,"about_ca_topic_score_gemma":0.000016569582,"teacher_disagreement_score":0.014209457,"about_ca_system_score_codex":0.000013522851,"about_ca_system_score_gemma":0.00027238615,"threshold_uncertainty_score":0.46843204},"labels":[],"label_agreement":null},{"id":"W4406194215","doi":"10.1016/j.jhazmat.2025.137170","title":"Nanoplastic-induced antibody liquid-liquid phase separation: Insights into potential immunotoxic implications","year":2025,"lang":"en","type":"article","venue":"Journal of Hazardous Materials","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Program for the Scientific Activities of Selected Returned Overseas Professionals in Shaanxi Province; Natural Science Foundation of Shaanxi Province","keywords":"Separation (statistics); Liquid liquid; Phase (matter); Liquid phase; Antibody; Chromatography; Chemistry; Materials science; Immunology; Biology; Physics; Thermodynamics; Computer science; Organic chemistry","score_opus":0.009317008022971566,"score_gpt":0.3353423388147787,"score_spread":0.3260253307918071,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406194215","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9844423,0.001030914,0.012062119,0.00094057457,0.0009977991,0.00028084556,0.000020284651,0.0000111827085,0.00021398133],"genre_scores_gemma":[0.9986102,0.00025903882,0.00035186915,0.00020567737,0.00032566817,0.00002235638,0.00008812821,0.000012531936,0.00012453781],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99845815,0.00020183605,0.0008018654,0.00022555444,0.00014603777,0.00016658471],"domain_scores_gemma":[0.99857205,0.0000138151545,0.00044713638,0.00042023504,0.0004634326,0.00008331009],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000437305,0.0001633338,0.00029989704,0.00012247283,0.00018274071,0.00008947018,0.00031396403,0.00018230079,0.000080741396],"category_scores_gemma":[0.00022276602,0.00014159147,0.00013023058,0.00012534628,0.00006412159,0.000019445475,0.00008319051,0.00008933486,0.000012398601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015356172,0.0002666739,0.000005813103,0.0000290815,0.00010119291,0.0000046436217,0.000056966397,0.000011909939,0.9968742,0.000450068,0.0003210779,0.00034272822],"study_design_scores_gemma":[0.0012667096,0.0012269084,0.00044091386,0.00002923094,0.000050392642,0.000043036034,0.000032215314,0.0000024602941,0.97865975,0.00027118126,0.017844323,0.00013286913],"about_ca_topic_score_codex":0.000005710364,"about_ca_topic_score_gemma":0.0000037342345,"teacher_disagreement_score":0.018214468,"about_ca_system_score_codex":0.00004230139,"about_ca_system_score_gemma":0.000405304,"threshold_uncertainty_score":0.57739323},"labels":[],"label_agreement":null},{"id":"W4406271893","doi":"10.1016/j.psj.2025.104804","title":"A novel and quick egg yolk immunoglobulin y antibody extraction method leveraging the protein liquid-liquid phase separation principle","year":2025,"lang":"en","type":"article","venue":"Poultry Science","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Yolk; Chromatography; Extraction (chemistry); Antibody; Chemistry; Liquid phase; Liquid liquid; Immunology; Biology; Food science; Physics","score_opus":0.02030235457143822,"score_gpt":0.40367374374346743,"score_spread":0.38337138917202923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406271893","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7177221,0.00043533655,0.27949554,0.0010817441,0.00008973771,0.00045789394,0.000006503278,0.000015687394,0.0006954479],"genre_scores_gemma":[0.9920593,0.000027402304,0.0070353355,0.00024028339,0.00003980404,0.00007085034,0.00002082471,0.0000042252373,0.00050199754],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99878705,0.00009423827,0.00022177665,0.0004925746,0.00018780612,0.00021655585],"domain_scores_gemma":[0.99918014,0.000021712813,0.000100401456,0.00047247656,0.00017087594,0.000054390508],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016526659,0.0001142012,0.00008852001,0.000053062035,0.00047862317,0.00009923344,0.00031412742,0.0000733799,0.0000071198415],"category_scores_gemma":[0.0005218922,0.00008893744,0.000035516347,0.00037878766,0.00027394315,0.000032560474,0.0001364457,0.0001223111,0.000003052408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023137844,0.00009996219,0.00038318508,0.0000129560985,0.0000060212865,1.6739386e-7,0.00009180176,0.000029701303,0.9949979,0.0011061827,0.000005312428,0.0030354145],"study_design_scores_gemma":[0.00056727475,0.00022569211,0.008942454,0.000018635677,0.0000082986635,0.000014693568,0.00022394209,0.001174596,0.9645952,0.00006417119,0.024030043,0.00013497275],"about_ca_topic_score_codex":0.00005162092,"about_ca_topic_score_gemma":0.000005105535,"teacher_disagreement_score":0.27433717,"about_ca_system_score_codex":0.000036125424,"about_ca_system_score_gemma":0.0003416195,"threshold_uncertainty_score":0.36812308},"labels":[],"label_agreement":null},{"id":"W4406299684","doi":"10.1016/j.greeac.2025.100204","title":"An integrated protocol based on workflows of imaged capillary isoelectric focusing (icIEF) for in-depth protein heterogenous characterization: High-efficient fractionation and online mass spectrometry detection","year":2025,"lang":"en","type":"article","venue":"Green Analytical Chemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Advanced Electrophoresis Solutions (Canada)","funders":"FedDev Ontario","keywords":"Isoelectric focusing; Fractionation; Mass spectrometry; Characterization (materials science); Chromatography; Chemistry; Protocol (science); Workflow; Analytical Chemistry (journal); Computer science; Materials science; Nanotechnology; Biochemistry; Database; Medicine","score_opus":0.009179031354357693,"score_gpt":0.2740224805959824,"score_spread":0.2648434492416247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406299684","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.79793215,0.0000127055255,0.1945683,0.00017122486,0.000012763475,0.0071565784,0.000049908263,0.000019321638,0.00007702121],"genre_scores_gemma":[0.99417615,0.0000012844392,0.0019482815,0.00006861603,0.000060046244,0.0031273633,0.00048800948,0.000013353336,0.00011687252],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987924,0.00006945242,0.00036643576,0.00044310436,0.00014743328,0.00018116279],"domain_scores_gemma":[0.9992636,0.000021639524,0.00013387622,0.0003153443,0.00020189496,0.00006367392],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026107035,0.00016289538,0.00019218745,0.000120777906,0.00007165645,0.00002235458,0.00011030703,0.00021246003,0.000017325037],"category_scores_gemma":[0.00019844242,0.00016065469,0.000064832035,0.000473149,0.00007304599,0.0000073382344,0.000015758702,0.00017020984,2.2786044e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00064508803,0.00048370694,0.00084961695,0.00020303908,0.000017664235,7.355665e-7,0.000003238541,0.00023420542,0.98683435,0.000010316306,7.128745e-7,0.010717331],"study_design_scores_gemma":[0.0010493515,0.00024541465,0.010723861,0.000044348813,0.000016088994,0.0000011666739,0.000014610532,0.10115989,0.8863296,0.00006405821,0.00020874414,0.00014286267],"about_ca_topic_score_codex":0.000024914234,"about_ca_topic_score_gemma":0.000018157885,"teacher_disagreement_score":0.196244,"about_ca_system_score_codex":0.000105687475,"about_ca_system_score_gemma":0.00013971857,"threshold_uncertainty_score":0.6551308},"labels":[],"label_agreement":null},{"id":"W4406917173","doi":"10.1016/j.chroma.2025.465733","title":"Bioseparation using membrane chromatography: Innovations, and challenges","year":2025,"lang":"en","type":"review","venue":"Journal of Chromatography A","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Natural Science Foundation of China; McMaster University","keywords":"Chemistry; Chromatography; Membrane; Biochemistry","score_opus":0.05389169069835325,"score_gpt":0.3358150614941299,"score_spread":0.2819233707957766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406917173","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00072778115,0.99800754,0.00035599398,0.00006507148,0.0001821686,0.0003885567,0.000032097545,0.000008705266,0.00023210415],"genre_scores_gemma":[0.0007456844,0.99720377,0.0017522286,0.000027873584,0.00017440578,0.000017548715,0.000049706494,0.00002028208,0.000008505195],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981135,0.00023675083,0.000977277,0.00030380356,0.00020213194,0.00016652387],"domain_scores_gemma":[0.99814016,0.000040616564,0.0010448052,0.00038489784,0.00030448037,0.0000850409],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00060320523,0.0003117844,0.0009364383,0.0008005281,0.00009788642,0.000049621536,0.00026356682,0.00040341588,0.0000063580947],"category_scores_gemma":[0.00012064673,0.00025983033,0.0006209366,0.0006960775,0.00014026153,0.000013774248,0.00006386166,0.00022822357,4.3804937e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043094224,0.00028461035,0.00007319471,0.03543915,0.0014655654,0.000010251127,0.00005357559,0.0000012142265,0.0021390712,0.0015720134,0.00035093576,0.9585673],"study_design_scores_gemma":[0.00027689995,0.0001389954,0.000062326224,0.004010672,0.00042169925,0.00028085164,0.000026105987,0.0000019749832,0.00038125843,0.00011763739,0.99402416,0.00025743543],"about_ca_topic_score_codex":0.0000018679235,"about_ca_topic_score_gemma":0.0000027569542,"teacher_disagreement_score":0.9936732,"about_ca_system_score_codex":0.000014886195,"about_ca_system_score_gemma":0.0004555296,"threshold_uncertainty_score":0.9999854},"labels":[],"label_agreement":null},{"id":"W4407207002","doi":"10.1101/2025.02.03.636246","title":"P3a site-specific and cassette mutagenesis for seamless protein, RNA and plasmid engineering","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Mutagenesis; Plasmid; Protein engineering; P3a; Site-directed mutagenesis; Computational biology; Computer science; Biology; Genetics; Mutation; DNA; Gene; Biochemistry; Mutant","score_opus":0.009835344939876603,"score_gpt":0.21092561007478608,"score_spread":0.20109026513490946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407207002","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.979889,0.008502595,0.008339469,0.00029464695,0.00026841467,0.001698745,0.0009081807,0.00009336726,0.000005614662],"genre_scores_gemma":[0.98835826,0.0008282276,0.0094854,0.00010875556,0.00023102788,0.0008991044,0.000003993525,0.000057526264,0.00002771402],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980167,0.000060907827,0.00035230897,0.0010829733,0.00013339698,0.000353686],"domain_scores_gemma":[0.998401,0.000029800318,0.00016444917,0.000892344,0.00032267615,0.00018973347],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00044062364,0.00042012773,0.0003627669,0.00009349259,0.00013980093,0.00015805053,0.00024824837,0.00055278646,0.0000046788123],"category_scores_gemma":[0.00023124696,0.0004765375,0.00009628261,0.000116190255,0.00009396551,0.000007230493,0.00042949076,0.00026179675,0.0000016427246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006138079,0.00004229564,0.0009775255,0.0008553728,0.00007762503,0.000003016072,0.0000045479624,0.000034294404,0.99745506,0.00030933664,0.00016455613,0.000014980247],"study_design_scores_gemma":[0.0005195181,0.000052283383,0.012704536,0.00015323187,0.000045827303,2.4625301e-8,0.0000016898779,0.00040627123,0.9087324,0.0000021760375,0.07680153,0.0005805239],"about_ca_topic_score_codex":0.000010214647,"about_ca_topic_score_gemma":0.0000027012945,"teacher_disagreement_score":0.08872268,"about_ca_system_score_codex":0.000053807842,"about_ca_system_score_gemma":0.00022659049,"threshold_uncertainty_score":0.9997686},"labels":[],"label_agreement":null},{"id":"W4407335005","doi":"10.3390/pharmacy13010022","title":"A Physicochemical Stability Study of Pembrolizumab Vial Leftovers: Let Us Stop Pouring Good Money Down the Drain","year":2025,"lang":"en","type":"article","venue":"Pharmacy","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Université Laval","keywords":"Vial; Pembrolizumab; Business; Chemistry; Medicine; Chromatography; Internal medicine","score_opus":0.019560394304420484,"score_gpt":0.31283468280258675,"score_spread":0.2932742884981663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407335005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99528295,0.00039930598,0.00041224816,0.0005575143,0.0000939246,0.00068174646,0.000033225446,0.000017622893,0.0025214385],"genre_scores_gemma":[0.9994048,0.000020899193,0.00003438918,0.00022122142,0.00009650193,0.00008533739,0.000021399432,0.000008193628,0.00010726319],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987192,0.00025676098,0.00028363627,0.00038273365,0.0001644035,0.00019322163],"domain_scores_gemma":[0.99908984,0.000042121876,0.00008936924,0.00061950623,0.00010804156,0.000051121908],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041856154,0.00014457964,0.00016921102,0.000021859121,0.00010620216,0.000020417268,0.0003560752,0.000041399297,0.000051627605],"category_scores_gemma":[0.00018748517,0.00011610564,0.00010715212,0.00013270172,0.00012102254,0.0000063387392,0.00020727982,0.00016180689,0.0000030137705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000598256,0.001410981,0.015211941,0.000049560826,0.00012486891,6.5483516e-7,0.0005600301,0.000018544608,0.97685957,0.00016607161,0.0003109034,0.0046886033],"study_design_scores_gemma":[0.003376692,0.0001034602,0.01051545,0.0000068604377,0.000057641875,0.0000012206751,0.0006001696,0.00029098275,0.9670473,0.00025532726,0.017589085,0.00015586315],"about_ca_topic_score_codex":0.00016095472,"about_ca_topic_score_gemma":0.000022265624,"teacher_disagreement_score":0.017278181,"about_ca_system_score_codex":0.000032054228,"about_ca_system_score_gemma":0.0001333561,"threshold_uncertainty_score":0.47346506},"labels":[],"label_agreement":null},{"id":"W4407848736","doi":"10.1016/j.ijbiomac.2025.141393","title":"Influence of physicochemical conditions on liquid-liquid phase separation and stability of immunoglobulin Y for storage and application","year":2025,"lang":"en","type":"article","venue":"International Journal of Biological Macromolecules","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Chemistry; Chromatography; Liquid liquid; Liquid phase; Separation (statistics); Chemical engineering; Thermodynamics; Computer science; Physics; Engineering","score_opus":0.012647187523694836,"score_gpt":0.3405888113600742,"score_spread":0.32794162383637937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407848736","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9849539,0.00045749225,0.013796048,0.0003462798,0.000028444105,0.00020143442,0.00017880142,0.000002179752,0.000035431774],"genre_scores_gemma":[0.9991334,0.0001816381,0.00045695042,0.00010073393,0.000027559203,0.000019524789,0.000076520875,0.0000022294832,0.0000014547153],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992297,0.000062515704,0.00039770754,0.00015655582,0.00009549517,0.000057968038],"domain_scores_gemma":[0.9989364,0.000084094456,0.00029615167,0.00010793735,0.0005447766,0.000030597053],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025940884,0.00007741342,0.00015556293,0.000044575012,0.000024735571,0.0000072093185,0.00015630983,0.000091069836,0.0000027914755],"category_scores_gemma":[0.00047281833,0.000063074556,0.0000709327,0.000041688025,0.00026743195,0.0000077911145,0.000051991803,0.00005991315,9.572998e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025719043,0.00032829164,0.00046501288,0.000019570138,0.00006479167,2.838247e-7,0.000019579364,0.000058632057,0.9921115,0.0034166311,0.0000086136015,0.0009351674],"study_design_scores_gemma":[0.000987976,0.0015990854,0.006360552,0.00003131746,0.000012610425,0.0000064698697,0.00003408805,0.00005268305,0.9891119,0.001236744,0.0005108997,0.00005568153],"about_ca_topic_score_codex":0.0000031630575,"about_ca_topic_score_gemma":7.3805006e-7,"teacher_disagreement_score":0.014179501,"about_ca_system_score_codex":0.000015437676,"about_ca_system_score_gemma":0.000049070168,"threshold_uncertainty_score":0.25721055},"labels":[],"label_agreement":null},{"id":"W4407947075","doi":"10.1016/j.trac.2025.118212","title":"Recent developments of imaged capillary isoelectric focusing technology for in-depth biopharmaceutical characterization","year":2025,"lang":"en","type":"article","venue":"TrAC Trends in Analytical Chemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo; Advanced Electrophoresis Solutions (Canada)","funders":"Natural Sciences and Engineering Research Council of Canada; FedDev Ontario; University of Waterloo","keywords":"Isoelectric focusing; Biopharmaceutical; Characterization (materials science); Capillary action; Chromatography; Materials science; Chemistry; Nanotechnology; Biotechnology; Biology; Biochemistry; Composite material","score_opus":0.02124042239237097,"score_gpt":0.3356139367152863,"score_spread":0.3143735143229153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407947075","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904577,0.00092511193,0.0030214307,0.0012046023,0.000037090373,0.0001792061,0.000021507589,0.000017151,0.00413616],"genre_scores_gemma":[0.9980463,0.0003356588,0.0006889481,0.00006314005,0.000017777398,0.000048036905,0.00025560713,0.000008308727,0.0005362525],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988638,0.000026546413,0.0004299109,0.00036161926,0.00007921482,0.0002388827],"domain_scores_gemma":[0.9995557,0.000018453282,0.000065879365,0.00022941483,0.000088655135,0.000041916453],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024301297,0.00012749294,0.00020814552,0.00020302538,0.000024434623,0.0000071596583,0.00016571445,0.00027126638,0.000040944313],"category_scores_gemma":[0.00028586184,0.00013569796,0.00005702933,0.00091519125,0.0001128421,0.0000038897033,0.00004804598,0.00016219191,5.0978343e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017078414,0.0002437193,0.009988006,0.00007948776,0.000021889971,0.0000012158557,0.000007061496,0.0000017619052,0.8365768,0.000110345216,0.000024078381,0.15277481],"study_design_scores_gemma":[0.0010345723,0.000023141372,0.033383984,0.000024506458,0.000015908578,0.0000019773574,0.000015119391,0.0006768176,0.9539799,0.00016924011,0.010537354,0.00013747359],"about_ca_topic_score_codex":0.00000128361,"about_ca_topic_score_gemma":0.000006055361,"teacher_disagreement_score":0.15263733,"about_ca_system_score_codex":0.00007248472,"about_ca_system_score_gemma":0.00012494475,"threshold_uncertainty_score":0.5533602},"labels":[],"label_agreement":null},{"id":"W4408045891","doi":"10.1016/b978-0-443-23848-2.00008-5","title":"Basics of biopharmaceuticals development, production, and quality","year":2025,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"","keywords":"Production (economics); Quality (philosophy); Manufacturing engineering; Engineering; Economics; Epistemology; Philosophy; Microeconomics","score_opus":0.034357550882414566,"score_gpt":0.3102134476678426,"score_spread":0.27585589678542805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408045891","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00079066254,0.006380949,0.000053141877,0.00009922618,0.0001538434,0.0005616126,0.000050232524,0.0000131029565,0.9918972],"genre_scores_gemma":[0.009512222,0.00049297686,0.0011733606,0.00014280355,0.00008393369,0.000025088835,0.0000646828,0.000016578615,0.9884884],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988295,0.000042635784,0.00044891625,0.00044224574,0.00012475892,0.00011195592],"domain_scores_gemma":[0.9990875,0.000010472651,0.00018700866,0.00046435674,0.0001871376,0.00006353523],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045198636,0.00019382735,0.0002613971,0.000042758074,0.000057944944,0.000008216082,0.00012614657,0.00025973018,0.00002927751],"category_scores_gemma":[0.00014782831,0.00019008943,0.00007279343,0.000007814082,0.00021970675,0.0000010146947,0.00012904525,0.00013535409,0.0000037473278],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044460823,0.000015972288,0.00013344978,0.0003878854,0.00010898332,2.5815888e-7,0.000029861592,4.4501036e-8,0.010002514,0.0069660502,0.000057961497,0.98225254],"study_design_scores_gemma":[0.00009858461,0.00001573015,0.00025166958,0.000074392236,0.00002588259,0.000001222564,0.0000025014608,1.0840168e-7,0.078651555,0.0007200636,0.9199843,0.00017398142],"about_ca_topic_score_codex":1.2693778e-7,"about_ca_topic_score_gemma":0.000015581149,"teacher_disagreement_score":0.98207855,"about_ca_system_score_codex":0.0000143523785,"about_ca_system_score_gemma":0.00031442236,"threshold_uncertainty_score":0.77516216},"labels":[],"label_agreement":null},{"id":"W4408082942","doi":"10.1016/j.ab.2025.115825","title":"Advancing protein heterogeneity analysis: Nano-flow pressure mobilization for precise icIEF fractionation and online MS detection","year":2025,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Advanced Electrophoresis Solutions (Canada)","funders":"FedDev Ontario","keywords":"Fractionation; Mobilization; Nano-; Chromatography; Chemistry; Flow (mathematics); Chemical engineering; Mechanics; Engineering; Physics; Geography","score_opus":0.0062416670076727064,"score_gpt":0.28499747132597325,"score_spread":0.27875580431830055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408082942","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7654127,0.0011630552,0.23218358,0.0003427037,0.000035047455,0.0005613914,0.00012478471,0.000029721701,0.00014701359],"genre_scores_gemma":[0.9958181,0.00005018715,0.0020792747,0.00009854098,0.00007754519,0.00015749871,0.0007280141,0.000008456808,0.0009824296],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988003,0.000044421686,0.00029224184,0.0005602083,0.00012455626,0.00017827869],"domain_scores_gemma":[0.9991321,0.000027099453,0.000097000026,0.0003795249,0.00028111177,0.00008316685],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027313,0.0001513266,0.00017567063,0.00007629673,0.00013577074,0.000037715137,0.00010306493,0.0002602734,0.000013679883],"category_scores_gemma":[0.00075363636,0.00015401324,0.00014620523,0.00037787057,0.00008025461,0.000009966553,0.000052581338,0.000086578,4.6696994e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000172643,0.00020504081,0.0021559072,0.00016201993,0.00038785662,9.090014e-8,0.000004482951,0.0006882059,0.9876849,0.00004576076,0.000064540494,0.008428572],"study_design_scores_gemma":[0.0003758674,0.0000590473,0.003079106,0.000015117315,0.0003741103,8.72833e-7,0.000025768484,0.06370457,0.9241208,0.00019266237,0.007895502,0.00015657782],"about_ca_topic_score_codex":0.000010557879,"about_ca_topic_score_gemma":0.00006380489,"teacher_disagreement_score":0.23040535,"about_ca_system_score_codex":0.000035056142,"about_ca_system_score_gemma":0.000076164004,"threshold_uncertainty_score":0.6280477},"labels":[],"label_agreement":null},{"id":"W4409277183","doi":"10.1101/2025.04.06.647494","title":"Identifying Modulators of the Post-Antibiotic Effect","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Antibiotics; Medicine; Biology; Microbiology","score_opus":0.008464854852241509,"score_gpt":0.23214958096207713,"score_spread":0.2236847261098356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409277183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99439245,0.0022693905,0.000788094,0.00013762161,0.001102436,0.00096835557,0.00026103863,0.000050742747,0.000029870285],"genre_scores_gemma":[0.99893206,0.000096241674,0.0006138589,0.00011906208,0.0001241679,0.000055344964,8.5956077e-7,0.000034593402,0.000023816778],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978943,0.00031750594,0.00045409164,0.0007867354,0.00025907255,0.0002883051],"domain_scores_gemma":[0.99694544,0.00002544502,0.00037371085,0.002133278,0.0004310191,0.000091123635],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00069493096,0.0003572037,0.0003811408,0.000092083166,0.00012706041,0.000057987956,0.0008582394,0.00054616405,0.000009465149],"category_scores_gemma":[0.00064243237,0.0003005637,0.00033138058,0.00027364466,0.00018094106,0.000004673932,0.00091997016,0.00040416128,0.0000061369988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033103017,0.000065688204,0.029740838,0.00068940775,0.00013352578,8.136689e-7,0.0000030040326,0.000034397064,0.9690009,0.00024232245,0.000050233328,0.000005786067],"study_design_scores_gemma":[0.00020603402,0.000036943857,0.20189184,0.00019227866,0.000071003466,4.288411e-9,7.6722375e-7,0.000041128853,0.7962139,0.0000015995431,0.0011057239,0.000238752],"about_ca_topic_score_codex":0.0000403766,"about_ca_topic_score_gemma":0.000003202159,"teacher_disagreement_score":0.17278695,"about_ca_system_score_codex":0.00006275916,"about_ca_system_score_gemma":0.0005297474,"threshold_uncertainty_score":0.9999446},"labels":[],"label_agreement":null},{"id":"W4410194398","doi":"10.1016/j.ijpharm.2025.125662","title":"Thermostabilization of a model viral-vectored oral thin film vaccine","year":2025,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; Brockhouse Institute for Materials Research; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; McMaster University","keywords":"Virology; Medicine; Materials science","score_opus":0.028491824200702835,"score_gpt":0.3708746564245389,"score_spread":0.34238283222383603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410194398","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92477334,0.0014779987,0.06944116,0.0020214359,0.00059900776,0.00014152231,0.00004671116,0.0000055223486,0.0014932812],"genre_scores_gemma":[0.99708205,0.0004191299,0.0016908337,0.00039800332,0.00006333167,0.0000016837535,0.000018350227,0.0000056028052,0.00032102884],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991956,0.00004301664,0.00040069825,0.00009175964,0.00020360637,0.00006535517],"domain_scores_gemma":[0.99879265,0.000011807315,0.0002632103,0.00011669538,0.00078133633,0.000034278113],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031767445,0.00007359887,0.00010776067,0.000081733655,0.000026006315,0.000010173163,0.00032257623,0.000059074417,0.0000498759],"category_scores_gemma":[0.00019078831,0.000065568405,0.00009716095,0.00005354901,0.000031124873,0.000009692765,0.00008291091,0.00009446927,4.5953806e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006168107,0.00023848105,0.0023464244,0.000014245117,0.00023306266,0.000001435007,0.00011586241,0.017073201,0.96798617,0.0033138448,0.00031436118,0.00774609],"study_design_scores_gemma":[0.0015161778,0.000092125054,0.0013378076,0.0000267871,0.000042320113,0.000010344506,0.00003893607,0.07035538,0.90248036,0.0027341158,0.021283524,0.00008212533],"about_ca_topic_score_codex":0.0000018558505,"about_ca_topic_score_gemma":0.000002782955,"teacher_disagreement_score":0.072308674,"about_ca_system_score_codex":0.00003079062,"about_ca_system_score_gemma":0.0001547641,"threshold_uncertainty_score":0.26738018},"labels":[],"label_agreement":null},{"id":"W4410221878","doi":"10.1016/j.xphs.2025.103823","title":"Relationships between surface tensiometry properties and fluorescence intensity of dark and light exposed monoclonal antibody Nivolumab/Opdivo® by using the contact angle method: A pilot study","year":2025,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Chicoutimi","funders":"Horizon 2020 Framework Programme; Innovative Medicines Initiative; Istituto Oncologico Veneto; European Commission; Innovative Health Initiative; European Federation of Pharmaceutical Industries and Associations","keywords":"Nivolumab; Contact angle; Fluorescence; Monoclonal antibody; Intensity (physics); Materials science; Analytical Chemistry (journal); Optics; Chemistry; Chromatography; Antibody; Composite material; Physics; Medicine; Immunology; Cancer; Internal medicine","score_opus":0.15803525107777705,"score_gpt":0.4001090245727583,"score_spread":0.24207377349498127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410221878","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917797,0.004303853,0.0025757302,0.0010160878,0.000055412445,0.00022692434,0.000005698912,0.0000020208174,0.000034566],"genre_scores_gemma":[0.9973584,0.000110794645,0.0024349177,0.00005806219,0.00002148953,6.325069e-7,5.341759e-7,0.0000021617116,0.000013038509],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987039,0.0003944784,0.00034789336,0.00019619089,0.00023059794,0.00012696299],"domain_scores_gemma":[0.99928117,0.00011193476,0.00017454346,0.00010488813,0.000240234,0.000087231354],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0028678118,0.000087472145,0.0001980413,0.000051084946,0.00030171734,0.0000495032,0.00021249094,0.000038547125,0.0000022126358],"category_scores_gemma":[0.0005458843,0.000051918665,0.000030374744,0.00028565477,0.00045309126,0.000022676144,0.00012600073,0.00021439228,5.385119e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014119686,0.000120101315,0.291387,0.000012548423,0.00003454404,4.842741e-7,0.00008781346,0.0000049651094,0.70740646,0.000015814672,0.00003407977,0.000755002],"study_design_scores_gemma":[0.00092133984,0.0016529141,0.24884216,0.00006414125,0.00013362755,0.000027921475,0.0021420438,0.0021024293,0.7431733,0.00019400353,0.00060757896,0.00013853902],"about_ca_topic_score_codex":0.000031643776,"about_ca_topic_score_gemma":0.0000030740591,"teacher_disagreement_score":0.04254484,"about_ca_system_score_codex":0.000012461351,"about_ca_system_score_gemma":0.000119567754,"threshold_uncertainty_score":0.23205964},"labels":[],"label_agreement":null},{"id":"W4410372363","doi":"10.1021/acs.molpharmaceut.4c01268","title":"Anomalous Clouding Behavior of Polysorbate 80─Deciphering the Role of Nonesterified Components","year":2025,"lang":"en","type":"article","venue":"Molecular Pharmaceutics","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Polysorbate; Chromatography; Pharmacology; Pulmonary surfactant; Medicine; Biochemistry","score_opus":0.019382352713654107,"score_gpt":0.30923061588200235,"score_spread":0.2898482631683482,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410372363","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901771,0.00435302,0.0036289413,0.00007662033,0.00011575467,0.00037386498,0.000022433764,0.000009145154,0.0012431471],"genre_scores_gemma":[0.9991407,0.00009588085,0.00045051897,0.0001504165,0.000013814747,0.00003718977,0.00002474385,0.000012754958,0.00007398832],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903345,0.00011708277,0.00032883967,0.00021529205,0.0001379199,0.00016742983],"domain_scores_gemma":[0.9992026,0.000011989026,0.00013896184,0.0004912601,0.00011501798,0.0000401847],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024275537,0.00012573719,0.00015886615,0.00003532046,0.000058096604,0.000009652692,0.000328084,0.00008714453,0.000009239116],"category_scores_gemma":[0.000040884406,0.00011169988,0.00011525406,0.00015273949,0.00014136743,0.0000023513512,0.0001689282,0.00009791975,0.0000010976516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007626587,0.00013324177,0.012550246,0.000036173275,0.000064940505,0.0000015067802,0.00004448404,0.000048974023,0.9787242,0.00040619614,0.0000035978758,0.007910198],"study_design_scores_gemma":[0.00042485129,0.00003122143,0.0073710023,0.000014189522,0.00007309862,0.0000030664878,0.00006793488,0.000425215,0.9797379,0.00008547467,0.011671624,0.000094415554],"about_ca_topic_score_codex":0.000016515203,"about_ca_topic_score_gemma":0.00000156293,"teacher_disagreement_score":0.0116680255,"about_ca_system_score_codex":0.000011733136,"about_ca_system_score_gemma":0.000051421623,"threshold_uncertainty_score":0.4554989},"labels":[],"label_agreement":null},{"id":"W4410871845","doi":"10.1016/j.jcoa.2025.100229","title":"Improvement in protein separation by pH excursion modulated ion-exchange chromatography","year":2025,"lang":"en","type":"article","venue":"Journal of Chromatography Open","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Research Council Canada; McMaster University","keywords":"Excursion; Ion chromatography; Chromatography; Ion exchange; Separation (statistics); Chemistry; Ion; Computer science; Machine learning; Political science; Organic chemistry","score_opus":0.00770514388176471,"score_gpt":0.2891565325507011,"score_spread":0.28145138866893643,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410871845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912739,0.0034913898,0.0017242,0.00070940953,0.00014736624,0.0011830721,0.00001830523,0.0000074444606,0.0014449088],"genre_scores_gemma":[0.9985368,0.00031596603,0.0005995324,0.00019898004,0.000038515427,0.00009134997,0.000056230037,0.000011161016,0.00015144638],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984945,0.0001428306,0.0006587356,0.00028172787,0.00021461882,0.00020756615],"domain_scores_gemma":[0.99894047,0.0000066169137,0.00039889742,0.00035997457,0.00020767198,0.00008634466],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007881458,0.00017239405,0.0002814145,0.00031917298,0.00008298539,0.000099492136,0.00056851044,0.0001674035,0.00003795045],"category_scores_gemma":[0.000041892694,0.0001548793,0.00019744417,0.0006398704,0.000075404445,0.000036894933,0.00014030012,0.00015226609,0.0000012948572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026123176,0.00044775257,0.0049144435,0.000067599736,0.000102039376,0.0000022751244,0.00004590577,0.00000817652,0.9804345,0.000087779874,0.006581652,0.0070466716],"study_design_scores_gemma":[0.0031643794,0.00071925414,0.03134393,0.00024378298,0.000026893451,0.00000986448,0.00011293111,0.00008246863,0.89338934,0.0015195361,0.06910905,0.0002785442],"about_ca_topic_score_codex":0.000052232834,"about_ca_topic_score_gemma":0.000035673227,"teacher_disagreement_score":0.0870451,"about_ca_system_score_codex":0.000029557423,"about_ca_system_score_gemma":0.00013020357,"threshold_uncertainty_score":0.63157946},"labels":[],"label_agreement":null},{"id":"W4411315374","doi":"10.1016/j.jchromb.2025.124705","title":"Refining proteoform characterization in biopharmaceuticals: A paradigm for the impact of pI markers and carrier ampholytes in imaged capillary isoelectric focusing tandem mass spectrometry","year":2025,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Advanced Electrophoresis Solutions (Canada)","funders":"FedDev Ontario","keywords":"Chemistry; Isoelectric focusing; Chromatography; Tandem mass spectrometry; Mass spectrometry; Tandem; Capillary electrophoresis; Capillary action; Biochemistry; Enzyme","score_opus":0.010182108191178086,"score_gpt":0.2989916300911023,"score_spread":0.2888095218999242,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411315374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9862304,0.007070938,0.0060733226,0.00020427199,0.00003156515,0.00032908993,0.000016158525,0.0000018957473,0.00004236584],"genre_scores_gemma":[0.99801683,0.0011650873,0.000724335,0.000031514835,0.000025495132,0.000019492541,0.0000072922867,0.0000066252387,0.0000033012223],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99908525,0.000087930275,0.000446412,0.00012758041,0.000086843356,0.0001659812],"domain_scores_gemma":[0.9994228,0.000060576065,0.00027496502,0.00012832678,0.00007572718,0.000037615355],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008740616,0.00010208567,0.00021250008,0.00037074074,0.000045366254,0.000024550292,0.000113712675,0.000085477106,0.000003497924],"category_scores_gemma":[0.00018537593,0.00007221964,0.0001621709,0.0006226509,0.00008381061,0.000015296935,0.000016772829,0.00013798145,1.4718911e-8],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036357067,0.000048507154,0.20618117,0.000047366455,0.0000873289,0.0000011557303,0.00003501409,0.0000050950393,0.78957605,0.00003283972,0.000004953277,0.003616976],"study_design_scores_gemma":[0.0014459377,0.00030457193,0.80624133,0.00008995562,0.000028262724,0.000019549805,0.000057955567,0.00039438717,0.19064163,0.0004001642,0.00028339194,0.00009284197],"about_ca_topic_score_codex":0.000015921136,"about_ca_topic_score_gemma":0.000006544392,"teacher_disagreement_score":0.60006016,"about_ca_system_score_codex":0.00003715377,"about_ca_system_score_gemma":0.00015823585,"threshold_uncertainty_score":0.29450315},"labels":[],"label_agreement":null},{"id":"W4411987473","doi":"10.1016/j.ejps.2025.107191","title":"Monoacyl phospholipids to replace polysorbates as interfacial stabilizers in parenteral monoclonal antibody formulations","year":2025,"lang":"en","type":"article","venue":"European Journal of Pharmaceutical Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Phospholipid Research Center; CMC Microsystems","keywords":"Monoclonal antibody; Chemistry; Pharmacology; Antibody; Medicine; Immunology","score_opus":0.029413113424967188,"score_gpt":0.3954604860836022,"score_spread":0.366047372658635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411987473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98540664,0.00060425466,0.0059007946,0.0023591125,0.00031129335,0.0001397701,0.000005641366,0.000004942558,0.0052675703],"genre_scores_gemma":[0.9977101,0.00007636308,0.00127726,0.00072972826,0.00007691601,0.0000015717808,0.000001993469,0.0000044911008,0.00012154186],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985753,0.0003108003,0.00045709775,0.00024189033,0.00019205356,0.00022280117],"domain_scores_gemma":[0.99948853,0.0000323755,0.00009642831,0.00012564745,0.000100816476,0.00015621028],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016516144,0.000102170314,0.00012621115,0.00012318006,0.00010513109,0.000064096086,0.00044288393,0.000021326148,0.0000780821],"category_scores_gemma":[0.00051589106,0.00008311178,0.00008403435,0.0003412958,0.00020724998,0.00002027817,0.00013335489,0.00015512884,0.000012051012],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011090433,0.0003797095,0.11342186,0.000019823743,0.000047004174,0.000019684192,0.00043330912,0.0010848148,0.84444493,0.0014613307,0.00084735255,0.036731154],"study_design_scores_gemma":[0.0024813362,0.001470165,0.15428254,0.00013264919,0.00003308632,0.00004133243,0.0005881086,0.0013515576,0.6082881,0.0007345562,0.23019353,0.00040305516],"about_ca_topic_score_codex":0.000005628297,"about_ca_topic_score_gemma":0.0000037835243,"teacher_disagreement_score":0.23615682,"about_ca_system_score_codex":0.00003015197,"about_ca_system_score_gemma":0.00014747158,"threshold_uncertainty_score":0.33892},"labels":[],"label_agreement":null},{"id":"W4413807897","doi":"10.29017/scog.v48i2.1744","title":"Determining The Role of Ion Exchange in Permeability Alteration During Asp Injection: A Laboratory-Scale Study Using Cmg Reactive Transport Modeling","year":2025,"lang":"en","type":"article","venue":"Scientific Contributions Oil and Gas","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Scale (ratio); Permeability (electromagnetism); Chemistry; Ion transporter; Ion exchange; Biophysics; Ion; Biochemistry; Membrane; Physics; Biology; Organic chemistry","score_opus":0.008384325952834306,"score_gpt":0.2630483244375554,"score_spread":0.2546639984847211,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413807897","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99797386,0.000474878,0.00094525894,0.00010189345,0.0001311502,0.00020290034,0.00008627399,0.000006490806,0.00007726681],"genre_scores_gemma":[0.9997716,0.000012566285,0.00002858176,0.000004846869,0.000022257687,0.000053270163,0.00004222886,0.0000024389344,0.00006221064],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906516,0.00014113887,0.00024147458,0.00033072138,0.00009596467,0.0001255693],"domain_scores_gemma":[0.9992706,0.0000104729825,0.000054981247,0.00028345844,0.00035471687,0.000025767824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009034882,0.00007594962,0.00010321733,0.00007231539,0.0003962629,0.000036345984,0.000077523364,0.00005756401,0.0000030096585],"category_scores_gemma":[0.00011954947,0.00006526868,0.000034625475,0.00033062443,0.00012280967,0.000016120197,0.000037358972,0.00008028964,1.5087087e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014045881,0.00051789347,0.17721407,0.00004562546,0.000024642683,3.1223098e-7,0.0021769889,0.000983363,0.80853224,0.00006413227,0.0000010767444,0.010299177],"study_design_scores_gemma":[0.0034959686,0.0002066021,0.3710182,0.000117618096,0.00011588936,0.000004374103,0.009661216,0.06741529,0.5447068,0.0013607808,0.0014817895,0.00041546492],"about_ca_topic_score_codex":0.000086991015,"about_ca_topic_score_gemma":0.0007750397,"teacher_disagreement_score":0.26382545,"about_ca_system_score_codex":0.000047396225,"about_ca_system_score_gemma":0.000116999574,"threshold_uncertainty_score":0.30477738},"labels":[],"label_agreement":null},{"id":"W4414353774","doi":"10.1101/2025.09.17.676805","title":"Predicting the Dynamic Viscosity of High-Concentration Antibody Solutions with a Chemically Specific Coarse-Grained Model","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"Deutsche Forschungsgemeinschaft","keywords":"Viscosity; Rheology; Molecular dynamics; Work (physics); Biopharmaceutical; Force field (fiction)","score_opus":0.009415873495165933,"score_gpt":0.22578444518049118,"score_spread":0.21636857168532525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414353774","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8921998,0.0011871188,0.10431877,0.00036401345,0.00017081751,0.0010033668,0.0006624277,0.00007357659,0.00002012101],"genre_scores_gemma":[0.9929531,0.00039265119,0.006284192,0.00007059935,0.000085471795,0.00016100828,0.000013889415,0.000030107301,0.00000896618],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99798155,0.00013450069,0.00047973933,0.0008011177,0.00026056432,0.0003425204],"domain_scores_gemma":[0.9974181,0.000023378076,0.00041358458,0.0014502519,0.000599113,0.00009558633],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00053645787,0.00033673813,0.00033201542,0.000049042923,0.00021207632,0.00006413864,0.00055506744,0.00040724484,0.000005023623],"category_scores_gemma":[0.00015204451,0.00028504638,0.00012702553,0.00024074972,0.00030574293,0.000009134003,0.00036972883,0.00042112687,0.0000012829885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011188067,0.00015257076,0.0019205727,0.00014680307,0.00011723515,7.359334e-7,0.00000939752,0.0018519786,0.9947533,0.00089633226,0.000035833633,0.0000033624503],"study_design_scores_gemma":[0.00089344184,0.00010225938,0.035189256,0.00029380157,0.00015981632,2.8306507e-8,0.0000087893,0.056600828,0.905481,0.00002044202,0.00063005433,0.0006202875],"about_ca_topic_score_codex":0.000037069753,"about_ca_topic_score_gemma":0.000010114147,"teacher_disagreement_score":0.10075333,"about_ca_system_score_codex":0.00010165079,"about_ca_system_score_gemma":0.00090850185,"threshold_uncertainty_score":0.9999602},"labels":[],"label_agreement":null},{"id":"W4415228131","doi":"10.1016/j.sbi.2025.103167","title":"Membrane protein reconstitution : New possibilities for structural biology, biophysical methods, and antibody/drug discovery","year":2025,"lang":"en","type":"editorial","venue":"Current Opinion in Structural Biology","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Biological and Environmental Research","keywords":"Membrane protein; Protein structure; Structural biology; Protein–protein interaction; Membrane; Protein stability","score_opus":0.024963079010470682,"score_gpt":0.4090258806647776,"score_spread":0.3840628016543069,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415228131","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.08180722,0.029814342,0.007957459,0.00044763356,0.8706553,0.0036130864,0.005596024,0.00006572833,0.000043234457],"genre_scores_gemma":[0.13636033,0.010755749,0.02285676,0.000055016273,0.7193628,0.0012363893,0.107454814,0.00011998419,0.0017981386],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964429,0.00064720615,0.0008145696,0.0014681922,0.00010423524,0.0005228886],"domain_scores_gemma":[0.9983332,0.0003169625,0.0003730642,0.00062985014,0.00022134361,0.00012555282],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00053054345,0.00058271224,0.0007776353,0.0001839593,0.00017348616,0.00008088881,0.00047873255,0.0011624374,0.00001293367],"category_scores_gemma":[0.0020559595,0.00048251398,0.000243406,0.00015827842,0.0008469525,0.00002669339,0.00033359806,0.0006720075,7.972511e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030597632,0.00010694674,0.0026904114,0.0053977584,0.00040348835,2.8946795e-7,0.00025506679,0.000007146089,0.5940396,0.046243537,0.14902757,0.19876838],"study_design_scores_gemma":[0.002204256,0.0004185221,0.00053746195,0.0003627651,0.000041006973,0.0000036622398,0.000051286253,0.00013234481,0.020134898,0.029754063,0.94539714,0.0009625683],"about_ca_topic_score_codex":0.00020795531,"about_ca_topic_score_gemma":0.000030384053,"teacher_disagreement_score":0.7963696,"about_ca_system_score_codex":0.00008890671,"about_ca_system_score_gemma":0.0009287932,"threshold_uncertainty_score":0.99976265},"labels":[],"label_agreement":null},{"id":"W4415355151","doi":"10.1016/j.xphs.2025.104030","title":"Emerging perspectives on leveraging physiologically based biopharmaceutics modeling (PBBM) for BCS class III biowaivers: A webinar summary","year":2025,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"National Institutes of Health","keywords":"Biopharmaceutics Classification System; Biopharmaceutics; Bioequivalence; Class (philosophy); Regulatory science; Drug class; IVIVC; Drug development","score_opus":0.06816441908297706,"score_gpt":0.3930700985033729,"score_spread":0.32490567942039583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415355151","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83344173,0.0073840553,0.14594524,0.009969109,0.00062006013,0.0005478279,0.000019547939,0.000023057257,0.0020493516],"genre_scores_gemma":[0.9934082,0.0007121396,0.004204414,0.0014461578,0.00015683714,0.000009099222,0.0000023648363,0.000005099772,0.000055695957],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9985328,0.00014016972,0.00039145022,0.00035690475,0.0002731978,0.00030553102],"domain_scores_gemma":[0.9991574,0.00010683524,0.00016023831,0.0001319255,0.0003098079,0.00013376819],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013795212,0.00015338146,0.00020342814,0.00013832697,0.00032600216,0.000060875216,0.00046167048,0.00009120759,0.000025743875],"category_scores_gemma":[0.00038386756,0.000115384064,0.00021776615,0.00029447302,0.0003476093,0.000018998944,0.000070382266,0.0002264003,8.9258754e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015652574,0.00058102066,0.00054017693,0.000080863145,0.00011453138,0.000004411182,0.00016684765,0.02505592,0.9524254,0.003300402,0.0007044643,0.015460692],"study_design_scores_gemma":[0.003803027,0.0012177774,0.00020937232,0.00017337155,0.0001224679,0.000007671139,0.0036423402,0.5817724,0.30837774,0.001613005,0.098630175,0.00043064487],"about_ca_topic_score_codex":0.0000015090832,"about_ca_topic_score_gemma":3.719392e-7,"teacher_disagreement_score":0.6440477,"about_ca_system_score_codex":0.00006108674,"about_ca_system_score_gemma":0.00030859484,"threshold_uncertainty_score":0.47052255},"labels":[],"label_agreement":null},{"id":"W4416341307","doi":"10.1101/2025.11.17.688837","title":"A universal buffer system for native LC-MS analysis of antibody-based therapeutics","year":2025,"lang":"","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Analyte; Elution; Ammonium acetate; Mass spectrometry; Acetic acid; Hydrophilic interaction chromatography; Ammonium","score_opus":0.014090157066687651,"score_gpt":0.25905146649746424,"score_spread":0.2449613094307766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416341307","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6284154,0.0057911086,0.3489422,0.0003802815,0.0012198958,0.004302166,0.010727214,0.00014850196,0.000073249284],"genre_scores_gemma":[0.9942216,0.00039311624,0.00467272,0.00015505655,0.0001355542,0.00031330454,0.000022810722,0.00006409165,0.000021695529],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9953872,0.00053810835,0.0012002557,0.001820403,0.00042418716,0.00062986853],"domain_scores_gemma":[0.99302185,0.00015596446,0.0011816673,0.0025663811,0.0028355662,0.00023854927],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012866294,0.00081930764,0.0013822506,0.00070532755,0.0002613609,0.00009944214,0.0010537397,0.0012830849,0.000026214942],"category_scores_gemma":[0.00026307488,0.0009086049,0.0011282873,0.0017704874,0.0004351284,0.0000120369905,0.0003413457,0.00043132348,0.0000025660543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006524392,0.0005590519,0.0069987043,0.002236521,0.007588379,0.000002936529,0.000019330324,0.00094951375,0.97838,0.0025937043,0.000011370439,0.000008028686],"study_design_scores_gemma":[0.001544564,0.00024945426,0.024543261,0.00036163218,0.0050438205,2.3528615e-9,0.000032723725,0.017705,0.93481934,6.995092e-7,0.0147592295,0.0009402815],"about_ca_topic_score_codex":0.00006874934,"about_ca_topic_score_gemma":0.0000088676115,"teacher_disagreement_score":0.36580628,"about_ca_system_score_codex":0.00040740878,"about_ca_system_score_gemma":0.0025565736,"threshold_uncertainty_score":0.9993365},"labels":[],"label_agreement":null},{"id":"W59628349","doi":"10.1385/1-59259-073-x:27","title":"Lipoprotein Isolation and Analysis from Serum by Preparative Ultracentrifugation","year":2003,"lang":"en","type":"article","venue":"Atherosclerosis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Isolation (microbiology); Ultracentrifuge; Plasma lipoprotein; Analytical Ultracentrifugation; Lipoprotein; Chromatography; Chemistry; Biochemistry; Biology; Cholesterol; Bioinformatics","score_opus":0.008049864302929128,"score_gpt":0.22775265330476396,"score_spread":0.21970278900183485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W59628349","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9706798,0.0010274983,0.027311603,0.00009808736,0.000027870521,0.00025264962,0.00014159283,0.000015097389,0.00044577365],"genre_scores_gemma":[0.9977503,0.00024854,0.001304596,0.000082098886,0.000016917958,0.000048900005,0.00026607944,0.0000087247545,0.0002738409],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911976,0.0001497818,0.00016185311,0.00035947782,0.0000902555,0.00011887251],"domain_scores_gemma":[0.99949604,0.000013682109,0.000088161265,0.00028724503,0.000054374705,0.000060515013],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017396602,0.00010700409,0.000114108545,0.000022592983,0.00009349132,0.000035420595,0.000057841837,0.000118046366,0.00009488328],"category_scores_gemma":[0.00010739865,0.00010529193,0.000063754,0.00018025521,0.00004966971,0.000008185396,0.000012694781,0.000044647975,0.000007091575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022507827,0.00007013259,0.10190435,0.000002291727,0.0001718958,1.5531578e-8,0.00018914217,0.000017145285,0.8951407,0.00013244887,0.00013249886,0.0022168562],"study_design_scores_gemma":[0.0004409926,0.00008430049,0.21895252,0.0000032452374,0.00010981005,9.740905e-8,0.000079274905,0.00030844135,0.76686263,0.00032057113,0.012642814,0.00019531515],"about_ca_topic_score_codex":0.0001139333,"about_ca_topic_score_gemma":0.00007669409,"teacher_disagreement_score":0.1282781,"about_ca_system_score_codex":0.000014736835,"about_ca_system_score_gemma":0.000016301143,"threshold_uncertainty_score":0.42936802},"labels":[],"label_agreement":null},{"id":"W6892441811","doi":"10.5281/zenodo.10715975","title":"A Comprehensive Review of Protein Purification Techniques: Advancements, Challenges, and Future Prospects","year":2024,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Component (thermodynamics); Protein stability; Identification (biology); Context (archaeology)","score_opus":0.027143722110216484,"score_gpt":0.2683926203259137,"score_spread":0.24124889821569723,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6892441811","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0062371665,0.92040306,0.0033461086,0.01130303,0.00011341658,0.00471356,0.0003274401,0.00068340596,0.052872803],"genre_scores_gemma":[0.33315504,0.65642864,0.0035646465,0.0005161283,0.0005428624,0.0000040060313,0.003992405,0.0010260985,0.00077020546],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99907076,0.00015558254,0.0001829725,0.00033669046,0.0001410459,0.00011294346],"domain_scores_gemma":[0.99916786,0.000002501856,0.000058784444,0.00034802858,0.00036804142,0.00005477351],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034907306,0.00008562705,0.00009443257,0.000051292493,0.00020462206,0.000060776605,0.00023326512,0.000046470752,0.00037047744],"category_scores_gemma":[0.00011882648,0.00008295622,0.000029552883,0.0001422518,0.00009564224,0.000013664109,0.00022417575,0.000095596304,0.00007531264],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035167053,0.00007810654,1.7758738e-7,0.0061652684,0.00003056854,0.000001575337,0.00015563553,6.7658405e-8,0.17701164,0.011226212,0.0056941323,0.79960144],"study_design_scores_gemma":[0.00008140541,0.0001876261,0.00008729245,0.00043082304,0.0000060502107,0.000025188994,0.0000731167,0.00000591254,0.02248707,0.00016277569,0.9763714,0.000081328],"about_ca_topic_score_codex":7.583963e-7,"about_ca_topic_score_gemma":4.0640504e-8,"teacher_disagreement_score":0.97067726,"about_ca_system_score_codex":0.000023016892,"about_ca_system_score_gemma":0.000005119887,"threshold_uncertainty_score":0.40564683},"labels":[],"label_agreement":null},{"id":"W6892616362","doi":"10.5281/zenodo.10715976","title":"A Comprehensive Review of Protein Purification Techniques: Advancements, Challenges, and Future Prospects","year":2024,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Component (thermodynamics); Protein stability; Identification (biology); Context (archaeology)","score_opus":0.027143722110216484,"score_gpt":0.2683926203259137,"score_spread":0.24124889821569723,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6892616362","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0062371665,0.92040306,0.0033461086,0.01130303,0.00011341658,0.00471356,0.0003274401,0.00068340596,0.052872803],"genre_scores_gemma":[0.33315504,0.65642864,0.0035646465,0.0005161283,0.0005428624,0.0000040060313,0.003992405,0.0010260985,0.00077020546],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99907076,0.00015558254,0.0001829725,0.00033669046,0.0001410459,0.00011294346],"domain_scores_gemma":[0.99916786,0.000002501856,0.000058784444,0.00034802858,0.00036804142,0.00005477351],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034907306,0.00008562705,0.00009443257,0.000051292493,0.00020462206,0.000060776605,0.00023326512,0.000046470752,0.00037047744],"category_scores_gemma":[0.00011882648,0.00008295622,0.000029552883,0.0001422518,0.00009564224,0.000013664109,0.00022417575,0.000095596304,0.00007531264],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035167053,0.00007810654,1.7758738e-7,0.0061652684,0.00003056854,0.000001575337,0.00015563553,6.7658405e-8,0.17701164,0.011226212,0.0056941323,0.79960144],"study_design_scores_gemma":[0.00008140541,0.0001876261,0.00008729245,0.00043082304,0.0000060502107,0.000025188994,0.0000731167,0.00000591254,0.02248707,0.00016277569,0.9763714,0.000081328],"about_ca_topic_score_codex":7.583963e-7,"about_ca_topic_score_gemma":4.0640504e-8,"teacher_disagreement_score":0.97067726,"about_ca_system_score_codex":0.000023016892,"about_ca_system_score_gemma":0.000005119887,"threshold_uncertainty_score":0.40564683},"labels":[],"label_agreement":null},{"id":"W6927721266","doi":"10.3389/fpsyt.2023.1286101.s004","title":"Image_2_Burnout in residents during the first wave of the COVID-19 pandemic: a systematic review and meta-analysis.pdf","year":2024,"lang":"en","type":"other","venue":"Figshare","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Burnout; Pandemic; Systematic review; Risk factor; Epidemiology; Professional psychology; Coronavirus disease 2019 (COVID-19); Meta-analysis","score_opus":0.06821152853729942,"score_gpt":0.3168120137787906,"score_spread":0.24860048524149117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6927721266","genre_codex":"review","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000069940165,0.898974,0.0000016619733,0.0012004809,0.000016569495,0.003611418,0.083518974,0.000022761064,0.012647117],"genre_scores_gemma":[0.018986043,0.0058452543,0.000019799105,0.005151965,0.00007980668,0.004577143,0.015641727,0.00025580463,0.94944245],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987984,0.00022759193,0.00036563398,0.00035174403,0.00015240465,0.0001042517],"domain_scores_gemma":[0.9986258,0.000027753751,0.0003134345,0.00095761725,0.000034365446,0.000041000727],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000264962,0.00017908477,0.00071991177,0.00005461946,0.00003235904,0.000024623672,0.0003435463,0.00016167738,0.039792243],"category_scores_gemma":[0.0016975541,0.000090734546,0.0005049396,0.00023256533,0.000025248575,0.0000012074046,0.0002457584,0.00014434522,0.00012072654],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000041884746,0.000020458341,0.00008740704,0.5856911,0.017816698,0.000005483427,0.00007111874,0.0000011649489,0.00004805891,0.000002550924,0.39625058,0.0000011977658],"study_design_scores_gemma":[0.00041481317,0.000027103059,0.0010481267,0.032778244,0.20606464,0.00008609562,0.000069409245,0.000008982938,0.0004157558,0.00009174107,0.7581852,0.0008098836],"about_ca_topic_score_codex":0.000061837745,"about_ca_topic_score_gemma":0.001297177,"teacher_disagreement_score":0.93679535,"about_ca_system_score_codex":0.000023962768,"about_ca_system_score_gemma":0.0000676968,"threshold_uncertainty_score":0.9610855},"labels":[],"label_agreement":null},{"id":"W6930129833","doi":"10.5281/zenodo.12066909","title":"le paradoxe du pouvoir pdf","year":2024,"lang":"fr","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Context (archaeology); Power (physics); Proposition; Order (exchange)","score_opus":0.014545905903496041,"score_gpt":0.2259025825754355,"score_spread":0.21135667667193944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930129833","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00038343278,0.0044733793,0.0044352664,0.005323517,0.00036860115,0.00071345863,0.000477711,0.00026646152,0.9835582],"genre_scores_gemma":[0.21864602,0.0015291566,0.00038878727,0.000498248,0.0011924781,3.0516762e-7,0.0061659934,0.005952669,0.7656264],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99750024,0.00053603965,0.00035043145,0.0009147156,0.00026754005,0.0004310593],"domain_scores_gemma":[0.9982884,0.0000075693406,0.00014302587,0.0009137882,0.00039833086,0.00024891004],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0006433341,0.0002983968,0.00023168548,0.00015295246,0.0009671626,0.0006611767,0.0011075629,0.00037077078,0.12368361],"category_scores_gemma":[0.000700694,0.00033752737,0.00016014668,0.00030617628,0.00042315852,0.000011521658,0.0012588587,0.00040387965,0.15669395],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007558812,0.00032819822,0.0000018411548,0.00040634556,0.00019907205,0.000019945395,0.00029935053,0.000009799258,0.015602359,0.045213353,0.8551549,0.082689255],"study_design_scores_gemma":[0.0003625828,0.0002257358,0.00005902412,0.00006899792,0.000032876582,0.000110684006,0.00015088184,0.00006968202,0.0018260406,0.000520171,0.99622625,0.00034707205],"about_ca_topic_score_codex":0.000027943315,"about_ca_topic_score_gemma":0.0000031600314,"teacher_disagreement_score":0.21826258,"about_ca_system_score_codex":0.000104128034,"about_ca_system_score_gemma":0.00002887313,"threshold_uncertainty_score":0.9999077},"labels":[],"label_agreement":null},{"id":"W6930164572","doi":"10.5281/zenodo.11943381","title":"the fire from within carlos castaneda pdf","year":2024,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Portrait; MAGIC (telescope); Quarter (Canadian coin); Geologist; Accident (philosophy)","score_opus":0.01821566761701082,"score_gpt":0.23815703098827354,"score_spread":0.21994136337126272,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930164572","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002737227,0.0059629558,0.00043134866,0.00076047616,0.00032297906,0.00059920707,0.0012069219,0.0003479481,0.9900944],"genre_scores_gemma":[0.0241531,0.000828373,0.00014685933,0.00016700815,0.0007306988,2.672794e-7,0.0063015493,0.0055177286,0.9621544],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99861276,0.00025092112,0.00019104827,0.0005157927,0.00022355582,0.00020590007],"domain_scores_gemma":[0.9988219,0.0000061712544,0.00010631578,0.00081551267,0.00014694118,0.000103138766],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00035163,0.00016727329,0.00011212154,0.00004503803,0.00063693954,0.00048314597,0.0008399549,0.00018833372,0.017918868],"category_scores_gemma":[0.0003630653,0.00013841833,0.00006719193,0.00014027249,0.00020373588,0.000002982348,0.0007040708,0.00025551606,0.024418268],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002892215,0.000025576082,2.2065657e-7,0.000038537783,0.00008584022,0.000004891025,0.00009480619,9.838018e-7,0.003017712,0.0005425236,0.980395,0.015764974],"study_design_scores_gemma":[0.00012606496,0.0000762466,0.000006775151,0.000033521,0.000016152328,0.000015260299,0.00012438624,0.000027035454,0.00088038825,0.00018780908,0.9983478,0.00015852565],"about_ca_topic_score_codex":0.00008360823,"about_ca_topic_score_gemma":0.00001180105,"teacher_disagreement_score":0.027940026,"about_ca_system_score_codex":0.000042036903,"about_ca_system_score_gemma":0.0000084484045,"threshold_uncertainty_score":0.9829789},"labels":[],"label_agreement":null},{"id":"W6930264642","doi":"10.5281/zenodo.12141047","title":"Tausch und tausch dimensionen pdf","year":2024,"lang":"de","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"History of medicine; Metabolic disease; Squire","score_opus":0.020888930988795244,"score_gpt":0.2596202435532888,"score_spread":0.23873131256449354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930264642","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00085040176,0.01967906,0.0023436109,0.0018800523,0.00070700963,0.0015514909,0.0012092845,0.00048656343,0.97129256],"genre_scores_gemma":[0.09419283,0.004443208,0.00064223004,0.00060193357,0.0017704973,5.791312e-7,0.021884764,0.011278788,0.8651852],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9965656,0.0006137011,0.00047725003,0.0013028091,0.0004741658,0.0005665188],"domain_scores_gemma":[0.99747753,0.000008996123,0.00021187481,0.0013887569,0.00057173974,0.0003411081],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0008753658,0.00042206908,0.0003203365,0.00025601895,0.0010464769,0.0008716069,0.0012993702,0.0005212559,0.12508686],"category_scores_gemma":[0.00067569653,0.00044637662,0.0001834132,0.00045557437,0.00038792565,0.000012909129,0.001968813,0.0006130876,0.2917944],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010271542,0.00026162362,0.0000010344268,0.00039229743,0.00043297844,0.000020770583,0.00019457207,0.000008052076,0.030727766,0.0019488786,0.9340054,0.031903934],"study_design_scores_gemma":[0.00041574586,0.00030939546,0.00003529657,0.0001061697,0.00010584207,0.000035989964,0.00008899803,0.00007362816,0.0024407636,0.00026600054,0.9956549,0.0004672734],"about_ca_topic_score_codex":0.000021970316,"about_ca_topic_score_gemma":0.0000011077376,"teacher_disagreement_score":0.16670752,"about_ca_system_score_codex":0.00014191224,"about_ca_system_score_gemma":0.000019736,"threshold_uncertainty_score":0.9997988},"labels":[],"label_agreement":null},{"id":"W6930313325","doi":"10.5281/zenodo.13018205","title":"vancouver sun run training","year":2024,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Training (meteorology); Work (physics); Government (linguistics); Clothing","score_opus":0.031845484690300276,"score_gpt":0.25519935348163353,"score_spread":0.22335386879133326,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930313325","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000047069647,0.0015748157,0.0017958385,0.00018882017,0.00029336903,0.0003941707,0.00046734663,0.0005594872,0.9946791],"genre_scores_gemma":[0.025589263,0.000472676,0.0005079988,0.000277418,0.0009291933,2.05401e-7,0.005180891,0.010976488,0.9560659],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986656,0.0001618418,0.00016948892,0.0005561043,0.00019659939,0.0002504011],"domain_scores_gemma":[0.9990722,0.0000021391022,0.00008183567,0.00059699046,0.00012870615,0.00011815596],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00036287174,0.00017132734,0.00013682879,0.0001368031,0.00030434743,0.0002403415,0.0006152102,0.00020851874,0.021944918],"category_scores_gemma":[0.00026556707,0.0001782836,0.000077601915,0.00017133755,0.00013336336,0.0000036103231,0.00057883724,0.00022251482,0.008030521],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015086329,0.000033459346,1.2092475e-7,0.000093089984,0.000056197976,0.0000036774902,0.00013886293,7.4238045e-7,0.0036394156,0.00054903474,0.9589518,0.036518537],"study_design_scores_gemma":[0.0001684273,0.00008924178,0.0000053937283,0.000041029212,0.000013674353,0.00001638933,0.00012054575,0.000008684045,0.00045310962,0.000116882744,0.9987712,0.00019542767],"about_ca_topic_score_codex":0.000012276518,"about_ca_topic_score_gemma":0.0000051494408,"teacher_disagreement_score":0.03981942,"about_ca_system_score_codex":0.00003721341,"about_ca_system_score_gemma":0.0000072920443,"threshold_uncertainty_score":0.9927418},"labels":[],"label_agreement":null},{"id":"W6930446146","doi":"10.5281/zenodo.12467564","title":"deed of sale of car vehicle pdf","year":2024,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Deed; Download; Lease; Possession (linguistics); Legislation; Collectable; Toll; File Transfer Protocol","score_opus":0.017864888577921338,"score_gpt":0.24280807037267788,"score_spread":0.22494318179475653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930446146","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012872947,0.0019517031,0.00057582086,0.00010217784,0.00007531452,0.00037846464,0.0005865967,0.00011676305,0.99492586],"genre_scores_gemma":[0.35875311,0.00068021665,0.00043538806,0.00006192811,0.00028317,1.3134013e-7,0.0040999968,0.0056117536,0.6300743],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99909747,0.0001324372,0.0001914631,0.00029572993,0.00015845223,0.00012446016],"domain_scores_gemma":[0.99912006,0.0000021623775,0.0001244955,0.0004959522,0.00019919344,0.00005813399],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002506529,0.00009991657,0.00013812879,0.000107204,0.00008054315,0.000037493297,0.00046425828,0.00013960546,0.0149111],"category_scores_gemma":[0.00020883558,0.00010413558,0.00006604094,0.00015958925,0.00016493663,0.0000020126288,0.00043054076,0.00010436256,0.003788342],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003819493,0.00009084358,0.0000017665798,0.00040497462,0.00008839236,0.0000011372308,0.000095471085,0.0000014412996,0.17465086,0.0008361583,0.81496954,0.008821237],"study_design_scores_gemma":[0.00016017197,0.00013133675,0.00003382371,0.000042847227,0.000014013147,0.0000048856696,0.000042943164,0.0000071064014,0.021883715,0.00004468929,0.9775437,0.00009076366],"about_ca_topic_score_codex":0.000021371954,"about_ca_topic_score_gemma":8.874556e-7,"teacher_disagreement_score":0.36485156,"about_ca_system_score_codex":0.000015433054,"about_ca_system_score_gemma":0.000005859321,"threshold_uncertainty_score":0.99698734},"labels":[],"label_agreement":null},{"id":"W6930514983","doi":"10.5281/zenodo.12643221","title":"DOWNLOAD [PDF] {EPUB} De la prison à la louange","year":2024,"lang":"fr","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Prison; Context (archaeology); Poison control; French","score_opus":0.01480315834559336,"score_gpt":0.25395845577780285,"score_spread":0.23915529743220948,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930514983","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010231026,0.0063420227,0.003180938,0.0014432208,0.00018208224,0.0006619236,0.0007439669,0.00030433762,0.9861184],"genre_scores_gemma":[0.20064257,0.004460056,0.0010215202,0.0005147187,0.0010924037,8.3771454e-7,0.007877166,0.006788713,0.777602],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966712,0.0014854933,0.0003099926,0.0008130718,0.00026296914,0.00045725814],"domain_scores_gemma":[0.9984885,0.000024425173,0.00013890749,0.00080927735,0.00027418157,0.00026471523],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0014129378,0.00030148486,0.00022059046,0.00016150354,0.0005806697,0.00089334446,0.0010021736,0.00058536377,0.09058783],"category_scores_gemma":[0.0010566176,0.0003264783,0.00014921237,0.00030694992,0.0005780355,0.000010687601,0.0010859994,0.0005978977,0.059555378],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008583616,0.00033074807,0.0000055593227,0.00056496,0.00018992921,0.000034183504,0.00064267014,0.000006703189,0.029877486,0.009290369,0.75995636,0.1990152],"study_design_scores_gemma":[0.0003604656,0.00019821615,0.0001709282,0.00009228709,0.00004662019,0.00016667348,0.00011079382,0.000044224493,0.0024712202,0.0003172413,0.99569166,0.00032969608],"about_ca_topic_score_codex":0.000024496736,"about_ca_topic_score_gemma":0.0000013129312,"teacher_disagreement_score":0.23573528,"about_ca_system_score_codex":0.00018836957,"about_ca_system_score_gemma":0.000026672082,"threshold_uncertainty_score":0.9999187},"labels":[],"label_agreement":null},{"id":"W6930605246","doi":"10.5281/zenodo.14200751","title":"Boredom proneness is predicted by difficulties in emotion regulation that are mediated by corresponding problems with attention and cognitive flexibility","year":2024,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Boredom; Rumination; Cognition; Distraction; Association (psychology); Cognitive flexibility; Flexibility (engineering); Cognitive reappraisal","score_opus":0.019496161612857027,"score_gpt":0.235314585960975,"score_spread":0.21581842434811796,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930605246","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9865504,0.00077127595,0.0092651015,0.0006166068,0.000030239256,0.0008884395,0.0011787557,0.00017431316,0.00052487804],"genre_scores_gemma":[0.98948395,0.00011171101,0.000025051968,0.000029883056,0.000018960749,6.8269566e-7,0.009747779,0.00019264869,0.0003893176],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99869215,0.00028541652,0.0001695537,0.00048558772,0.00020058334,0.00016668961],"domain_scores_gemma":[0.999415,0.000012517329,0.00007283591,0.0001763174,0.00025461137,0.00006872574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047667147,0.0001145402,0.00009117409,0.000084285384,0.00037408955,0.0002924149,0.00013585402,0.00009353644,0.00026881497],"category_scores_gemma":[0.00026465688,0.00010515972,0.000018484934,0.00028611862,0.00017147507,0.00003285175,0.00015090802,0.00012463653,0.000030739822],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012108053,0.0005723039,0.003160895,0.00074214675,0.00014679483,0.000004516112,0.0030251697,0.000033953438,0.8731506,0.00015641133,0.04901338,0.06878307],"study_design_scores_gemma":[0.003924481,0.0014565191,0.24519585,0.000829326,0.00008486823,0.00009331158,0.003926166,0.010008442,0.098202445,0.0002095013,0.63512576,0.0009433261],"about_ca_topic_score_codex":0.000012773028,"about_ca_topic_score_gemma":0.0000018668848,"teacher_disagreement_score":0.7749481,"about_ca_system_score_codex":0.000055719607,"about_ca_system_score_gemma":0.0000050507056,"threshold_uncertainty_score":0.4288289},"labels":[],"label_agreement":null},{"id":"W6930761154","doi":"10.5281/zenodo.16099498","title":"FIG. 33 in Révision des données sédimentologiques et biostratigraphiques des gisements à vertébrés des sables de l'Orléanais, à Beaugency, Tavers et Le Bardon (Miocène Moyen; Loiret, France)","year":2025,"lang":"fr","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Tyrrell Museum","funders":"","keywords":"Scale (ratio); Work (physics); Sedimentary rock","score_opus":0.027734643915522356,"score_gpt":0.26785565761192737,"score_spread":0.240121013696405,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930761154","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.21841134,0.04052558,0.043826666,0.0057760533,0.0002790987,0.0037325071,0.002993149,0.0008603145,0.6835953],"genre_scores_gemma":[0.92623395,0.04494465,0.007428401,0.0005962119,0.00009214344,0.0000018960601,0.0045262882,0.0013165516,0.014859912],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9960253,0.0016722302,0.0005060558,0.00088511774,0.00027840905,0.0006328862],"domain_scores_gemma":[0.99828565,0.000030414842,0.00020950152,0.0006717566,0.0005839285,0.0002187652],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0014068125,0.00041326447,0.0003407166,0.00034152478,0.0011798437,0.0004627543,0.001013496,0.00043679043,0.007313332],"category_scores_gemma":[0.0014377639,0.00044900368,0.00014792879,0.00053087407,0.0012533764,0.00006418081,0.00078018964,0.00041252314,0.00025368252],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000804375,0.0028804985,0.0049136407,0.003454091,0.0007353186,0.00005727543,0.005397219,0.00023999227,0.13459499,0.042706314,0.124314725,0.67990154],"study_design_scores_gemma":[0.00077999535,0.00048379588,0.012429094,0.000595677,0.000028649978,0.000015286612,0.00043456402,0.00008264869,0.024619862,0.002812402,0.9572826,0.00043539677],"about_ca_topic_score_codex":0.0011461483,"about_ca_topic_score_gemma":0.00033254936,"teacher_disagreement_score":0.8329679,"about_ca_system_score_codex":0.0002660764,"about_ca_system_score_gemma":0.00009245523,"threshold_uncertainty_score":0.99979615},"labels":[],"label_agreement":null},{"id":"W6931140343","doi":"10.5281/zenodo.4115796","title":"Watch The Addams Family (2019) Full Movie Online Free Download Streaming HD 123Movies TV ihn","year":2020,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Download; Studio; Box office; The Internet; Sign (mathematics); Action (physics)","score_opus":0.033369592256844445,"score_gpt":0.2412393675594919,"score_spread":0.20786977530264747,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931140343","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86618537,0.0037291963,0.012644216,0.05200437,0.00027608944,0.0023863097,0.0057050115,0.001117159,0.055952292],"genre_scores_gemma":[0.9894062,0.00062197197,0.00042288762,0.0017792879,0.00035615318,2.1970062e-7,0.0060608624,0.0004698864,0.00088251027],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99838996,0.00031213643,0.00026016266,0.00047532996,0.00027296864,0.00028947246],"domain_scores_gemma":[0.9985644,0.000012189588,0.00009681996,0.00077999354,0.0003724402,0.00017412302],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00041132295,0.00015326621,0.00012731367,0.000026478987,0.0009912997,0.00026694237,0.0012848062,0.00008874246,0.001884654],"category_scores_gemma":[0.0011586893,0.00012704365,0.00007343237,0.00025382175,0.00020366986,0.000015640782,0.0012263051,0.00023172745,0.0013946404],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002615239,0.00023023412,0.000022253389,0.000070503665,0.000080658996,0.0000054104776,0.0008487903,0.00005913793,0.43952125,0.001016187,0.38795206,0.16993201],"study_design_scores_gemma":[0.00042639466,0.00028385894,0.001071256,0.0000064269593,0.000011082215,0.0000135669015,0.00035214558,0.00014808077,0.007836546,0.000057895933,0.9896308,0.00016193306],"about_ca_topic_score_codex":0.0000211219,"about_ca_topic_score_gemma":0.0000018711895,"teacher_disagreement_score":0.6016788,"about_ca_system_score_codex":0.000028401506,"about_ca_system_score_gemma":0.000009221111,"threshold_uncertainty_score":0.9993829},"labels":[],"label_agreement":null},{"id":"W6931193348","doi":"10.5281/zenodo.4761125","title":"Figs. 27–32. Leuctra maria, 27-28, 30-32 in Morphological Systematics Of Leuctra Duplicata Claassen, 1923 Species Group (Plecoptera: Leuctridae)","year":2017,"lang":"en","type":"other","venue":"Figshare","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Dorsum; Systematics; Taxonomy (biology); Tributary; Species group","score_opus":0.03959350621042248,"score_gpt":0.2689640908110059,"score_spread":0.22937058460058343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931193348","genre_codex":"other","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006275438,0.02524419,0.00009757393,0.00024798347,0.0006625484,0.0044246367,0.4328595,0.00020099868,0.535635],"genre_scores_gemma":[0.0853899,0.001678145,0.0017571928,0.00031224306,0.0018822377,0.0013501192,0.47618657,0.0007058411,0.43073776],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99714035,0.00020982142,0.00075272506,0.0010216251,0.00036761587,0.0005078522],"domain_scores_gemma":[0.9963685,0.000054462682,0.00096495484,0.0023072,0.00014649222,0.00015833492],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00026227767,0.0005795199,0.00090044225,0.00013082896,0.00007639582,0.00009450378,0.0011866505,0.0012920488,0.08267255],"category_scores_gemma":[0.0015588283,0.0005324016,0.00031140487,0.00011633234,0.00010391097,0.000009530249,0.00042722307,0.00046259759,0.00084828044],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003501384,0.0001834694,0.00015546642,0.0023337787,0.00009834134,0.000043460324,0.000014903433,0.0000015668462,0.0070817154,0.00007961908,0.98921984,0.00075282686],"study_design_scores_gemma":[0.0006002768,0.00012727085,0.002526486,0.0022491845,0.000026662605,0.000033319484,0.000018910703,0.00002274527,0.004509694,0.000027892716,0.9892568,0.0006007703],"about_ca_topic_score_codex":0.00006929188,"about_ca_topic_score_gemma":0.00033138896,"teacher_disagreement_score":0.10489724,"about_ca_system_score_codex":0.00007226584,"about_ca_system_score_gemma":0.00018122957,"threshold_uncertainty_score":0.99992967},"labels":[],"label_agreement":null},{"id":"W6931327003","doi":"10.5281/zenodo.5069005","title":"Análisis Comparativo de los Marcos Jurídicos e Institucionales de la Gobernanza Corporativa en Estados Unidos y Canadá / Comparative Analysis of the Legal and Institutional Frameworks of Corporate Governance in the United States and Canada","year":2021,"lang":"es","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Corporate governance; Corporate social responsibility; Good governance; Public management","score_opus":0.01856409078837901,"score_gpt":0.25587948429702007,"score_spread":0.23731539350864106,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931327003","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925572,0.0008112716,0.0011650572,0.0014914247,0.000013807778,0.00028354637,0.002147668,0.000005633435,0.0015243477],"genre_scores_gemma":[0.9972663,0.0009185573,0.00013181775,0.00021509093,0.000012090948,2.3957097e-7,0.0013778525,0.000042633197,0.000035441968],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99733627,0.0016664441,0.000293273,0.00027151324,0.00026632045,0.00016617915],"domain_scores_gemma":[0.9986749,0.00011381174,0.00031294464,0.00032919378,0.00048727082,0.00008186512],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006539715,0.00012840575,0.00021747596,0.00007534091,0.00047690238,0.00014431479,0.0004364288,0.00011651957,0.00015874745],"category_scores_gemma":[0.0005927577,0.000105140796,0.000039494833,0.0008950768,0.00074341113,0.000018525827,0.00036955354,0.00034796266,7.088433e-7],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017115736,0.0024708633,0.087819606,0.0014579138,0.0039532036,0.00018391396,0.017620834,0.05544207,0.105389394,0.6784825,0.029495912,0.01597226],"study_design_scores_gemma":[0.00073854986,0.0001134135,0.38876578,0.00012270277,0.00016681445,0.000083622515,0.0022116208,0.012353416,0.0105241025,0.0002367511,0.58446187,0.00022135356],"about_ca_topic_score_codex":0.033231884,"about_ca_topic_score_gemma":0.02879945,"teacher_disagreement_score":0.6782457,"about_ca_system_score_codex":0.00014724278,"about_ca_system_score_gemma":0.0002851632,"threshold_uncertainty_score":0.9889224},"labels":[],"label_agreement":null},{"id":"W6931480565","doi":"10.5281/zenodo.7697178","title":"Les oiseaux de l'île aux Basques et les Razades – Liste annotée pour le printemps, l'été et l'automne (édition 2001)","year":2001,"lang":"fr","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Centre Intégré de Santé et de Services Sociaux du Bas-Saint-Laurent","funders":"","keywords":"Context (archaeology); Statistical analysis; Western europe","score_opus":0.057434782852953406,"score_gpt":0.30807953220409845,"score_spread":0.25064474935114506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931480565","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2767843,0.019001598,0.10251124,0.12668976,0.0004461887,0.0023466754,0.0017605572,0.0013243987,0.46913525],"genre_scores_gemma":[0.96845067,0.0047457274,0.0013566092,0.0008174122,0.00028574423,5.401681e-7,0.0040393076,0.00082032656,0.019483691],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99653214,0.0015926615,0.00038710336,0.0006623778,0.00027667155,0.00054901984],"domain_scores_gemma":[0.99798524,0.00002691555,0.00017921744,0.00066662784,0.00085971144,0.0002822613],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001697117,0.0002576098,0.00019864536,0.00012374525,0.0015119,0.00062799884,0.0007801248,0.00028939525,0.0063918433],"category_scores_gemma":[0.0014118121,0.00029922006,0.00012463455,0.00030373794,0.00039947408,0.00006677027,0.00075090677,0.00044106218,0.0010959216],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047909055,0.0017273612,0.00029992868,0.0003728397,0.00020141069,0.000045004235,0.0012326426,0.0002876441,0.21888256,0.07642429,0.37986803,0.3201792],"study_design_scores_gemma":[0.00067267724,0.00029368166,0.0046673897,0.000067483896,0.000019982866,0.00016465335,0.0004540043,0.00065311504,0.015372942,0.0007314958,0.9765978,0.00030476283],"about_ca_topic_score_codex":0.00051012036,"about_ca_topic_score_gemma":0.000028689652,"teacher_disagreement_score":0.69166636,"about_ca_system_score_codex":0.00017102274,"about_ca_system_score_gemma":0.00008889686,"threshold_uncertainty_score":0.999946},"labels":[],"label_agreement":null},{"id":"W6931915694","doi":"10.5683/sp3/tolg9y","title":"UNI-CEN Boundaries (CBF-Harmonized Shorelines) - Census Division (CD) - 1881 - File Geodatabase format (WGS84 / EPSG:4326)","year":2022,"lang":"en","type":"dataset","venue":"Borealis","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Shapefile; North American Datum of 1927; File format; Documentation; Census; Geocoding; Data file; Boundary (topology)","score_opus":0.018160470943574515,"score_gpt":0.2702647773444348,"score_spread":0.2521043064008603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931915694","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00018274196,0.002384104,0.00010204148,0.00037101103,0.00037545233,0.00077200186,0.9954815,0.000059022084,0.0002721066],"genre_scores_gemma":[0.00022653003,0.0017512991,0.000275956,0.0006006163,0.00028002323,0.0004490502,0.99606884,0.000057549005,0.00029015317],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99680257,0.00032195315,0.0007234139,0.0010062617,0.0005603839,0.0005853977],"domain_scores_gemma":[0.996575,0.000055566208,0.00039886544,0.0024867547,0.00021822932,0.0002655835],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00060175225,0.0005706176,0.0005212554,0.00012245939,0.0007517205,0.00025326668,0.0010680609,0.0005215618,0.012351663],"category_scores_gemma":[0.00084743527,0.00054788886,0.00030240606,0.00018986418,0.00038621618,0.000015824646,0.0010454231,0.0005551897,0.000024254618],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026510775,0.00021596711,0.000009965256,0.0001341659,0.00008262781,0.000021920223,0.000019357709,0.0000031821046,0.00034394086,0.00003368818,0.9971285,0.0017415612],"study_design_scores_gemma":[0.000752171,0.00017223207,0.00024991625,0.00002112974,0.00007677923,0.00001921667,0.00006426213,0.000017688435,0.0008309994,0.00006904421,0.9970971,0.000629507],"about_ca_topic_score_codex":0.010535674,"about_ca_topic_score_gemma":0.0042670975,"teacher_disagreement_score":0.012327408,"about_ca_system_score_codex":0.00009943109,"about_ca_system_score_gemma":0.0005421164,"threshold_uncertainty_score":0.99969727},"labels":[],"label_agreement":null},{"id":"W6958872202","doi":"10.6084/m9.figshare.c.6627408","title":"Surgical treatments for postamputation pain: study protocol for an international, double-blind, randomised controlled trial","year":2024,"lang":"en","type":"other","venue":"Figshare","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Neuroma; Randomized controlled trial; Phantom pain; Clinical trial; Reinnervation; Psychological intervention; Neurotomy","score_opus":0.1029436207349971,"score_gpt":0.4171077326388063,"score_spread":0.3141641119038092,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6958872202","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000012633967,0.00007542847,0.000073066665,0.00004599064,0.00018251575,0.9112215,0.06644615,0.00008175306,0.021860972],"genre_scores_gemma":[0.00016349292,5.601045e-7,0.0000739549,0.000022187434,0.0008350581,0.753807,0.15196572,0.00014887689,0.092983134],"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","domain_scores_codex":[0.99860424,0.00015288561,0.0003521769,0.0005915675,0.00015067511,0.00014845887],"domain_scores_gemma":[0.9990904,0.00006223338,0.0002479702,0.00034244513,0.00018722426,0.00006974395],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003185519,0.00025155596,0.00034583884,0.00007479753,0.00003726035,0.00009627675,0.00022755917,0.00032452404,0.010546221],"category_scores_gemma":[0.0005881909,0.00019818888,0.0003192255,0.000034197583,0.0000061099727,0.0000039967263,0.000033988024,0.000057835427,0.00006012594],"study_design_candidate":"randomized_trial","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.6561941,0.0008218839,5.958664e-7,0.00017016547,0.0005085076,0.0000011576556,0.000016789418,8.482595e-7,0.000017059403,0.0000038765443,0.34108123,0.0011838124],"study_design_scores_gemma":[0.4912726,0.0012884758,2.9987882e-7,0.00007258355,0.000039779727,3.5891628e-7,0.000009088865,0.000051351795,0.000070610826,0.0000121930825,0.5070661,0.00011660142],"about_ca_topic_score_codex":0.000003726781,"about_ca_topic_score_gemma":0.000025173395,"teacher_disagreement_score":0.16598485,"about_ca_system_score_codex":0.000027083599,"about_ca_system_score_gemma":0.00013701593,"threshold_uncertainty_score":0.9903583},"labels":[],"label_agreement":null},{"id":"W7019295057","doi":"","title":"Forced degradation studies: an essential tool for the formulation development of vaccines","year":2013,"lang":"en","type":"review","venue":"Dove Medical Press (Taylor and Francis Group)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Forced degradation; Degradation (telecommunications); Bioprocess; Phase (matter); Protein degradation","score_opus":0.06574950254759222,"score_gpt":0.35871798464882765,"score_spread":0.29296848210123544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7019295057","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009438415,0.6255293,0.37295964,0.000013527134,0.00015041909,0.0012094193,0.000028387065,0.0000061398164,0.0000087597045],"genre_scores_gemma":[0.08897021,0.8975065,0.0050705494,0.00013233349,0.0010377216,0.0042149536,0.0029601564,0.00007662982,0.000030984622],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983298,0.000105999396,0.0007138614,0.0004071239,0.00026411843,0.00017907277],"domain_scores_gemma":[0.9988469,0.00017267115,0.00030200122,0.00039995046,0.00018770847,0.00009080042],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007587408,0.0002455915,0.0005838834,0.000027159418,0.00015470739,0.00002480549,0.00028868072,0.00035134002,0.000031070307],"category_scores_gemma":[0.0007095734,0.00014544374,0.00017274776,0.000052935455,0.00009114613,0.000012571763,0.00011387995,0.00012142505,9.361439e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003086556,0.000052885596,0.00000421047,0.003226644,0.00019206785,6.548801e-8,0.000091850714,2.816093e-7,0.00013265575,0.0002666868,0.000011234583,0.9959906],"study_design_scores_gemma":[0.0012107955,0.00023466001,0.00006637586,0.00010708585,0.0005397989,0.000006258364,0.00010862787,0.0121831875,0.0013702163,0.0002460053,0.983403,0.00052395795],"about_ca_topic_score_codex":0.000009286847,"about_ca_topic_score_gemma":0.000028432982,"teacher_disagreement_score":0.9954666,"about_ca_system_score_codex":0.000013816572,"about_ca_system_score_gemma":0.000012353657,"threshold_uncertainty_score":0.59310234},"labels":[],"label_agreement":null},{"id":"W7067319539","doi":"","title":"Les biens publics. Culture politique de la Louisiane franÃ§aise 1730 - 1770","year":2010,"lang":"en","type":"other","venue":"Library and Archives Canada (Government of Canada)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Politics; Narrative; Colonialism; Field (mathematics); Government (linguistics); Context (archaeology)","score_opus":0.0021508639052916488,"score_gpt":0.16612282285157923,"score_spread":0.16397195894628758,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7067319539","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018064635,0.002139564,0.00015275249,0.0014313031,0.000104648134,0.00020535,0.00096719956,0.0000131998195,0.9931795],"genre_scores_gemma":[0.46827516,0.0017826101,0.001975027,0.0013256746,0.00032530256,0.000028370341,0.00019454604,0.00015099932,0.5259423],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99862623,0.0001108335,0.0001773798,0.00032013017,0.00050788297,0.00025753517],"domain_scores_gemma":[0.99917656,0.000030173836,0.00015465623,0.00036988716,8.583997e-7,0.00026787096],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000018802433,0.00022526563,0.00020234895,0.000020136882,0.00007825681,0.000025120124,0.00028005044,0.00024109407,0.00028321097],"category_scores_gemma":[0.000014296616,0.00021038084,0.000043803255,0.00003406721,0.00018497978,0.0000070045567,0.000111375244,0.0002691609,3.7038037e-9],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047326987,0.00023078828,0.027902085,0.0010867635,0.00048748343,0.00010026626,0.00017279014,0.0000048423917,0.35086843,0.25675005,0.338203,0.02372021],"study_design_scores_gemma":[0.00018037083,0.00003160691,0.0053299316,0.000037200847,0.000010507077,0.000008122502,0.00015143881,0.000011049871,0.06406161,0.00035535768,0.9295972,0.0002256108],"about_ca_topic_score_codex":0.008320299,"about_ca_topic_score_gemma":0.052089255,"teacher_disagreement_score":0.5913942,"about_ca_system_score_codex":0.0000040436466,"about_ca_system_score_gemma":0.00152121,"threshold_uncertainty_score":0.9982834},"labels":[],"label_agreement":null},{"id":"W7067522421","doi":"","title":"Les pratiques de gouvernance de commissions scolaires du Québec","year":2012,"lang":"fr","type":"dissertation","venue":"Knowledge UdeS (Institutional Deposit of the University of Sherbrooke)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Context (archaeology); Participatory democracy; Democratic legitimacy","score_opus":0.009937641761341582,"score_gpt":0.2249879502289398,"score_spread":0.21505030846759823,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7067522421","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9080721,0.05317656,0.02267865,0.00037783425,0.0003034361,0.0004141848,0.00005476348,0.000014455383,0.014908],"genre_scores_gemma":[0.9902296,0.0018952689,0.0032267435,0.0000142092695,0.00011188204,0.0000024976641,0.00008736552,0.000012947599,0.0044194954],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987032,0.00029269463,0.0002918682,0.00028326435,0.00018167638,0.00024732962],"domain_scores_gemma":[0.9988086,0.000041280684,0.00026128933,0.00041619487,0.00032437922,0.0001482422],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027805177,0.00024342202,0.00027799653,0.000046256802,0.00075201126,0.000010236653,0.00078419683,0.0004829324,0.00010092761],"category_scores_gemma":[0.00024366973,0.00024175378,0.0003503512,0.00011256577,0.0009490004,0.00002347202,0.00018666929,0.00026383303,0.000009783176],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005373802,0.0014247813,0.22829856,0.0054047247,0.00040180513,0.0000031813386,0.018674888,0.0024615563,0.7170826,0.015498656,0.0022541143,0.00795775],"study_design_scores_gemma":[0.00038640847,0.000077829085,0.540861,0.0017755952,0.00020105869,0.000013790593,0.0007086575,0.0011690647,0.3330652,0.00005011626,0.12145228,0.00023900477],"about_ca_topic_score_codex":0.044796575,"about_ca_topic_score_gemma":0.39198452,"teacher_disagreement_score":0.3840174,"about_ca_system_score_codex":0.0013375487,"about_ca_system_score_gemma":0.0024301016,"threshold_uncertainty_score":0.98584324},"labels":[],"label_agreement":null},{"id":"W7092297805","doi":"10.5291/ill-data.8-04-994","title":"Internal and Centre-of-Mass Diffusion of Intrinsically Disordered Protein Tau under Liquid-Liquid Phase Separation","year":2025,"lang":"","type":"dataset","venue":"Institut Laue-Langevin","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Nautical Research Society","funders":"","keywords":"Phase (matter); Intrinsically disordered proteins; Diffusion; Phase transition","score_opus":0.009840349142280153,"score_gpt":0.29696451004465213,"score_spread":0.28712416090237197,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7092297805","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6427895,0.010243529,0.015180924,0.0008273866,0.00072336517,0.0041647693,0.3252339,0.000026935828,0.0008096965],"genre_scores_gemma":[0.7025237,0.0035897673,0.00041195788,0.0001435754,0.00021150027,0.00014683587,0.2924449,0.000021737456,0.0005059982],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99619246,0.0004397149,0.0014343823,0.0010921832,0.000423558,0.000417686],"domain_scores_gemma":[0.99698114,0.000052253126,0.00093084946,0.0013383849,0.0004756645,0.00022171963],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004941391,0.0006299218,0.0008979573,0.00021686725,0.00015110163,0.000053413056,0.0006937218,0.0009341432,0.00016097963],"category_scores_gemma":[0.00080519804,0.00061230554,0.00026616434,0.0002777417,0.00077130686,0.000025841078,0.0005937215,0.0004842778,0.0000050956173],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009922125,0.003054265,0.000058191636,0.0024859721,0.0004547207,0.0000115699395,0.00016225042,0.00002269358,0.95889586,0.0014074082,0.015423439,0.0081014745],"study_design_scores_gemma":[0.0044694906,0.002957182,0.000056232366,0.0009994723,0.0002499293,0.0000059370154,0.00012843136,0.000081604616,0.30838808,0.00007655201,0.6818984,0.00068870524],"about_ca_topic_score_codex":0.0002803467,"about_ca_topic_score_gemma":0.00073494733,"teacher_disagreement_score":0.66647494,"about_ca_system_score_codex":0.00007671822,"about_ca_system_score_gemma":0.00084798725,"threshold_uncertainty_score":0.99963284},"labels":[],"label_agreement":null},{"id":"W7094266579","doi":"","title":"Simulated moving bed reactor for p-xylene production: Optimal particle size","year":2015,"lang":"en","type":"article","venue":"Open Repository of the University of Porto (University of Porto)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Simulated moving bed; Raffinate; Particle (ecology); Pressure drop; Work (physics); Particle size; Yield (engineering)","score_opus":0.020277954427998672,"score_gpt":0.2227891958931474,"score_spread":0.20251124146514873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7094266579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966199,0.00007869467,0.0005262973,0.00058232376,0.00013565026,0.0005670283,0.000031919557,0.000008343304,0.0014498797],"genre_scores_gemma":[0.987278,0.000010123944,0.00414508,0.000007940421,0.000020949825,7.906589e-8,0.000017780938,0.000006330083,0.008513748],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913585,0.000093908035,0.00016532847,0.00030387018,0.000174956,0.00012606334],"domain_scores_gemma":[0.99829984,0.000018141332,0.00046937435,0.0006195941,0.00049294124,0.000100089266],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039917,0.00009634807,0.00022426834,0.000020675128,0.0002039037,0.0000056694516,0.000737303,0.00011193334,0.000035547015],"category_scores_gemma":[0.00013192267,0.00010896318,0.0001678623,0.00011578526,0.00036345053,0.00003928434,0.00040975554,0.000058253776,8.328155e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002531285,0.00054131,0.030608814,0.00010643993,0.00028223795,0.000011983856,0.0022631942,0.00075562036,0.9584025,0.00021842636,0.0037749663,0.00050322525],"study_design_scores_gemma":[0.0030911323,0.00061546406,0.06244098,0.00006911074,0.0002688696,0.000019733383,0.011185329,0.0005298561,0.884101,0.00008527827,0.037237603,0.0003556514],"about_ca_topic_score_codex":0.00089157704,"about_ca_topic_score_gemma":0.00009934032,"teacher_disagreement_score":0.0743015,"about_ca_system_score_codex":0.000041003677,"about_ca_system_score_gemma":0.00028634156,"threshold_uncertainty_score":0.44433895},"labels":[],"label_agreement":null},{"id":"W7113421734","doi":"","title":"Overproduction, separation and purification of affinity-tagged proteins from <i>Escherichia coli</i>","year":2019,"lang":"en","type":"article","venue":"Research Explorer (The University of Manchester)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Separation (statistics); Separation method; Component (thermodynamics); Diafiltration; Analyte","score_opus":0.032230128871962596,"score_gpt":0.2753101470843091,"score_spread":0.24308001821234654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7113421734","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969217,0.00032198412,0.00093367137,0.00088780385,0.000026081778,0.0006706449,0.000019721929,0.0000061429914,0.00021224206],"genre_scores_gemma":[0.9985389,0.00032060844,0.0009023605,0.000015116919,0.00003573301,0.0000040775626,0.000071311166,0.0000059511585,0.00010594882],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989188,0.0003043898,0.00012304209,0.00029112608,0.00024035167,0.00012233044],"domain_scores_gemma":[0.9989854,0.000037593127,0.00009822965,0.00054327806,0.00029150007,0.000043984764],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00069634273,0.00006800496,0.000108438195,0.000042178344,0.000111499634,0.000009290644,0.00023350175,0.00008437238,0.000061682],"category_scores_gemma":[0.00009915916,0.00006450993,0.000040795083,0.00013698544,0.00028972756,0.000018969657,0.0001175622,0.00012936862,0.00002599792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034206803,0.00010772561,0.0055241245,0.000058932947,0.000034248977,1.7839203e-7,0.0035871742,0.000013976715,0.9886101,0.00019444393,0.0003357402,0.0011913052],"study_design_scores_gemma":[0.0009722714,0.0003880757,0.18090156,0.00003612359,0.000018155883,6.83856e-7,0.008035799,0.00018804277,0.7501836,0.0005212014,0.058589358,0.00016514189],"about_ca_topic_score_codex":0.000032839525,"about_ca_topic_score_gemma":0.0000055462056,"teacher_disagreement_score":0.23842649,"about_ca_system_score_codex":0.000020137264,"about_ca_system_score_gemma":0.0000871376,"threshold_uncertainty_score":0.26306385},"labels":[],"label_agreement":null},{"id":"W7115819286","doi":"","title":"Environment-Responsive Membranes for Bioseparations","year":2008,"lang":"en","type":"dissertation","venue":"MacSphere (McMaster University)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Membrane; Polyvinylidene fluoride; Ternary operation; Ultrafiltration (renal); Synthetic membrane; Protein purification","score_opus":0.012288710693135791,"score_gpt":0.22283196382160902,"score_spread":0.21054325312847325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7115819286","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11146343,0.007562626,0.009356701,0.0004090844,0.0010343555,0.0046507637,0.0014085821,0.00013749766,0.86397696],"genre_scores_gemma":[0.022391072,0.0011152658,0.0009712185,0.000064311025,0.00011265909,0.000020470681,0.0036798965,0.00003656057,0.9716085],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989538,0.000074610434,0.00015721044,0.0005080955,0.000109399654,0.00019687756],"domain_scores_gemma":[0.99930865,0.000018528133,0.00014296945,0.00035580827,0.000089871864,0.00008419475],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000047553393,0.00023004338,0.00018283796,0.000072644,0.00021038277,0.000017497287,0.00027065733,0.00036946934,0.007038643],"category_scores_gemma":[0.000034103974,0.00026968718,0.00019634563,0.000088612,0.00006905152,0.000007136928,0.000035804722,0.00009821735,0.000045150253],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0100765135,0.00095773564,0.00065167923,0.0013330436,0.0012760881,0.000054544966,0.0023571674,0.0003859928,0.5366421,0.0023299211,0.018229298,0.4257059],"study_design_scores_gemma":[0.00061028945,0.00012069478,0.0003087823,0.000010146782,0.00005630224,0.0000025013808,0.0007926899,0.000016963178,0.04896021,0.00003724547,0.94879943,0.00028473363],"about_ca_topic_score_codex":0.000013024231,"about_ca_topic_score_gemma":0.00016545772,"teacher_disagreement_score":0.9305701,"about_ca_system_score_codex":0.00004339681,"about_ca_system_score_gemma":0.00014871442,"threshold_uncertainty_score":0.9999755},"labels":[],"label_agreement":null},{"id":"W7117657573","doi":"10.20944/preprints202512.2621.v1","title":"Investigation on a Freeze-Drying Process for Long-Term Stability of mRNA-LNPs","year":2025,"lang":"","type":"preprint","venue":"Preprints.org","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Bee Research Fund; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Dispersity; Thermostability; Trehalose; Gelatin; Sugar; Protein stability; Histidine","score_opus":0.17657545839273098,"score_gpt":0.373638558822889,"score_spread":0.197063100430158,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117657573","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867521,0.0005665302,0.0031494582,0.0006097091,0.0005941628,0.005319976,0.0005881279,0.000053618347,0.0023663465],"genre_scores_gemma":[0.99571085,0.00032971904,0.00024949913,0.00018096736,0.00019418553,0.0019071806,0.00085979473,0.000045105673,0.00052272726],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99372995,0.00057061354,0.0017934366,0.0027861285,0.0005101833,0.00060967775],"domain_scores_gemma":[0.99313617,0.00016011384,0.0013083399,0.0036038666,0.0014903789,0.0003011263],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0025250285,0.0007691274,0.0009236013,0.00017344588,0.00026511238,0.00003481862,0.0014165835,0.0012350093,0.00029535632],"category_scores_gemma":[0.0034548955,0.0008668104,0.0006746424,0.0002792094,0.00064414524,0.000019090383,0.0012888511,0.00081567996,0.0000334084],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00088985637,0.0005144612,0.68814105,0.0047135665,0.00025606574,4.2690672e-7,0.0006737681,0.00016898909,0.30230832,0.0002953699,0.0000032957296,0.0020348488],"study_design_scores_gemma":[0.00082238053,0.00014463055,0.27679896,0.00045464112,0.00011301784,9.723814e-7,0.000077535005,0.00012003121,0.71850425,0.0020373561,0.0004309696,0.0004952497],"about_ca_topic_score_codex":0.00006669482,"about_ca_topic_score_gemma":0.000069239635,"teacher_disagreement_score":0.41619593,"about_ca_system_score_codex":0.00022034057,"about_ca_system_score_gemma":0.001640769,"threshold_uncertainty_score":0.99937826},"labels":[],"label_agreement":null},{"id":"W7132914425","doi":"","title":"Development of MANufacturing on the GO (MANGO): A Cell-Free Synthetic Biology Approach to Portable On-Demand Biomanufacturing","year":2024,"lang":"","type":"dissertation","venue":"TSpace","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biomanufacturing; Synthetic biology; Protein expression; Cold chain; Production (economics); Variety (cybernetics)","score_opus":0.02064824077752915,"score_gpt":0.29002698483793304,"score_spread":0.2693787440604039,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7132914425","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9350669,0.001995703,0.0013062168,0.0007404776,0.00049537746,0.0018603198,0.000076902616,0.000033716442,0.0584244],"genre_scores_gemma":[0.9867534,0.00015804669,0.0019242438,0.00017642185,0.00011294055,0.00047690922,0.0008069607,0.00008940435,0.009501642],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963787,0.00023403455,0.0008569054,0.0015137653,0.00037538836,0.0006411992],"domain_scores_gemma":[0.9971371,0.00009715518,0.00043790296,0.0020074337,0.000104379316,0.00021597007],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009513214,0.0007499578,0.0005976905,0.0002485617,0.00034885883,0.000080789825,0.0011381713,0.0007619399,0.00012774243],"category_scores_gemma":[0.00019637527,0.0005671368,0.00029911214,0.00018635216,0.00013178185,0.0000036013057,0.0003106911,0.00055986695,0.00016688235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024018923,0.0029256004,0.000051868523,0.0059145,0.0013647444,0.0000103708935,0.032054234,0.000752558,0.9076769,0.0074763,0.003026798,0.03634428],"study_design_scores_gemma":[0.00029112317,0.00027280312,0.00032930923,0.00023129735,0.00007655726,0.0000030458953,0.0046266313,0.000043376487,0.9449747,0.00020786337,0.048367087,0.000576209],"about_ca_topic_score_codex":0.000047142785,"about_ca_topic_score_gemma":0.00007189886,"teacher_disagreement_score":0.051686544,"about_ca_system_score_codex":0.00015133548,"about_ca_system_score_gemma":0.0004520151,"threshold_uncertainty_score":0.999678},"labels":[],"label_agreement":null},{"id":"W72055654","doi":"","title":"CGMD simulation of interaction between hemagglutinin fusion peptides and lipid bilayer membranes","year":2008,"lang":"en","type":"article","venue":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; University of Tokyo; Mitacs; Ministry of Education, Culture, Sports, Science and Technology; York University","keywords":"Membrane; Lipid bilayer fusion; Lipid bilayer; Bilayer; Fusion; Hemagglutinin (influenza); Chemistry; Biophysics; Materials science; Biochemistry; Biology","score_opus":0.01877580839721529,"score_gpt":0.25690370509095367,"score_spread":0.23812789669373838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W72055654","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911175,0.00018386658,0.005477143,0.000060053862,0.000059190133,0.00014331006,0.000058358022,0.000011471093,0.0028891007],"genre_scores_gemma":[0.99762505,0.00015017897,0.00095636264,0.000016682223,0.000018504961,0.000008947171,0.0011638534,0.0000033762208,0.000057017838],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989995,0.000029800734,0.0005036321,0.00016562305,0.00020835856,0.00009309663],"domain_scores_gemma":[0.9990895,0.00005647267,0.00032343113,0.00022171816,0.00025162208,0.000057255154],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003107346,0.000096034346,0.00016897722,0.00010507335,0.000110983405,0.000013662608,0.00008882811,0.00010448442,0.000014764489],"category_scores_gemma":[0.00017689879,0.00008511115,0.000051681196,0.00014782896,0.00042369217,0.000065999615,0.00009008904,0.000040770974,0.0000010471024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010829158,0.0008534942,0.073377214,0.0007960983,0.00015157326,5.3840216e-7,0.00008163375,0.004180182,0.8856641,0.0054506743,0.00070967694,0.027651887],"study_design_scores_gemma":[0.0008625259,0.0005118029,0.31712037,0.00006611647,0.00004324911,0.000015276773,0.000028663186,0.00032344265,0.6187072,0.00012676184,0.061943397,0.00025121446],"about_ca_topic_score_codex":0.000012551912,"about_ca_topic_score_gemma":0.000005504874,"teacher_disagreement_score":0.26695693,"about_ca_system_score_codex":0.0000071349546,"about_ca_system_score_gemma":0.000043687316,"threshold_uncertainty_score":0.3470732},"labels":[],"label_agreement":null}]}