{"meta":{"query_hash":"11999f8c0094","filters":{"topic":"Quinazolinone synthesis and applications"},"cohort_total":151,"direct_labels_cover":0,"predictions_cover":151,"exported":151,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/11999f8c0094","api":"https://metacan.xera.ac/api/v1/cohort?topic=Quinazolinone+synthesis+and+applications"},"results":[{"id":"W1498165882","doi":"10.1107/s1600536809036708","title":"<i>N</i><sup>1</sup>,<i>N</i><sup>2</sup>-Bis(2,6-dimethylphenyl)-<i>N</i><sup>1</sup>-hydroxyformamidine<i>N</i>,<i>N</i>′-bis(2,6-dimethylphenyl)-<i>N</i>-oxidoformamidinium dichloromethane solvate","year":2009,"lang":"he","type":"article","venue":"Acta Crystallographica Section E Structure Reports Online","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Dimer; Benzoic acid; Chemistry; Medicinal chemistry; Hydrogen bond; Crystallography; Molecule; Organic chemistry","score_opus":0.009240110205667642,"score_gpt":0.24056499152030977,"score_spread":0.23132488131464213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1498165882","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95141494,0.007369877,0.0012223608,0.008229522,0.0021873533,0.0061095627,0.007978492,0.0045056627,0.010982239],"genre_scores_gemma":[0.9483441,0.010320018,0.0063909963,0.004545975,0.01044365,0.00061053695,0.012585223,0.0016900814,0.0050693895],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.95839506,0.0017330502,0.013157802,0.010058464,0.0072806436,0.009375003],"domain_scores_gemma":[0.96803176,0.002092037,0.008819845,0.012275486,0.003587221,0.0051936205],"candidate_categories":["metaepi_narrow","sts","scholarly_communication","open_science","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","sts","research_integrity"],"category_scores_codex":[0.0051542744,0.009001838,0.0086849425,0.0047625387,0.005359039,0.0024594082,0.0055915955,0.008114782,0.007268607],"category_scores_gemma":[0.002147134,0.009188215,0.0061876536,0.012870024,0.0033121726,0.005022209,0.002134753,0.012083655,0.00002698864],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028541891,0.008931718,0.004633131,0.0029599124,0.0068616234,0.0025853005,0.0045185103,0.062413722,0.85750985,0.0003689725,0.033919003,0.01244407],"study_design_scores_gemma":[0.008219303,0.0023773236,0.0016978227,0.0019495116,0.006260842,0.011012174,0.006884428,0.0362635,0.02052774,0.0055090967,0.8872109,0.012087354],"about_ca_topic_score_codex":0.0015777089,"about_ca_topic_score_gemma":0.00023344369,"teacher_disagreement_score":0.8532919,"about_ca_system_score_codex":0.0018720467,"about_ca_system_score_gemma":0.003149413,"threshold_uncertainty_score":0.99978864},"labels":[],"label_agreement":null},{"id":"W1522375633","doi":"10.1111/j.1747-0285.2011.01098.x","title":"Synthesis and Studies on Three‐Compartment Flavone‐Containing Combi‐Molecules Designed to Target EGFR, DNA, and MEK","year":2011,"lang":"en","type":"article","venue":"Chemical Biology & Drug Design","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Regional Health Centre; Royal Victoria Hospital","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Moiety; Biochemistry; Phosphorylation; Kinase; Quinazoline; In vivo; Small molecule; EGFR inhibitors; Epidermal growth factor receptor; Biology; Stereochemistry; Receptor","score_opus":0.05769860839415958,"score_gpt":0.2776764439545815,"score_spread":0.21997783556042194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1522375633","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99253094,0.0016067469,0.0025334756,0.00060997537,0.000036203983,0.00027422095,0.000026586962,0.000121492994,0.0022603804],"genre_scores_gemma":[0.9823299,0.00010551636,0.016653577,0.0002949607,0.000066729765,0.00046142426,0.000009749996,0.000029650104,0.000048459675],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99839383,0.0000751697,0.00037596698,0.00066301506,0.00008603398,0.00040595233],"domain_scores_gemma":[0.99803346,0.0012202222,0.000119302655,0.00034232685,0.00005707612,0.00022763219],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032988776,0.0003336053,0.0005478655,0.000055034812,0.0001822997,0.000020010286,0.00024048345,0.00016523318,0.00013934597],"category_scores_gemma":[0.00031945482,0.00027602338,0.00006514959,0.00007751216,0.00038750863,0.000031967968,0.0001583719,0.00015715999,0.0000462295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002164984,0.00019062767,0.0006771011,0.00003867224,0.00022856549,0.0000089675295,0.0010171857,0.0000015956286,0.9854115,0.006393483,0.0006249145,0.0051908423],"study_design_scores_gemma":[0.0002700011,0.000071100134,0.00011081832,0.00007322364,0.00009566345,0.000009894243,0.00053646846,0.00007678938,0.9906024,0.007333946,0.00049769646,0.00032203025],"about_ca_topic_score_codex":0.000013745285,"about_ca_topic_score_gemma":0.0000028808754,"teacher_disagreement_score":0.014120101,"about_ca_system_score_codex":0.00005297146,"about_ca_system_score_gemma":0.000024680063,"threshold_uncertainty_score":0.9999692},"labels":[],"label_agreement":null},{"id":"W1923817293","doi":"10.1107/s1600536813000275","title":"3,5-Diphenyl-1,2,4-dithiazolium tetrabromidoferrate(III)","year":2013,"lang":"en","type":"article","venue":"Acta Crystallographica Section E Structure Reports Online","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"","keywords":"Ring (chemistry); Dihedral angle; Crystallography; Chemistry; Stacking; Ion; Atom (system on chip); Salt (chemistry); Stereochemistry; Molecule; Hydrogen bond","score_opus":0.007279805048293221,"score_gpt":0.22587622106935523,"score_spread":0.218596416021062,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1923817293","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894383,0.00011318562,0.0001602334,0.0011862008,0.0005780822,0.00034063385,0.00011280089,0.00063046505,0.0074400795],"genre_scores_gemma":[0.9948522,0.00009832878,0.0013118223,0.0001995095,0.0014173271,0.00012440085,0.00068766024,0.000092516726,0.001216227],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99687386,0.000029902149,0.0010185932,0.00094378024,0.0005198287,0.00061402656],"domain_scores_gemma":[0.99730366,0.00008354983,0.0006454431,0.0012585479,0.00037699228,0.00033180448],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000114217044,0.0005168638,0.0005121707,0.00028295378,0.00041858782,0.0001789826,0.0003043856,0.00056562264,0.011558026],"category_scores_gemma":[0.000100148754,0.000455673,0.00032725418,0.00073362124,0.00023418268,0.00039921264,0.00009585277,0.0008033305,4.897718e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011968904,0.00020586312,0.0040573394,0.000060323546,0.00014264035,0.000027164451,0.000056391917,0.000028113767,0.9893835,0.000020602594,0.0041781617,0.0018279235],"study_design_scores_gemma":[0.00077881943,0.0000685399,0.05831695,0.00010186388,0.00024804167,0.002410415,0.00083548506,0.0004620067,0.00665149,0.012311389,0.9163789,0.0014360563],"about_ca_topic_score_codex":0.00064399315,"about_ca_topic_score_gemma":0.00033708202,"teacher_disagreement_score":0.982732,"about_ca_system_score_codex":0.00007694473,"about_ca_system_score_gemma":0.000102687496,"threshold_uncertainty_score":0.9997895},"labels":[],"label_agreement":null},{"id":"W1971903915","doi":"10.1007/s10593-011-0805-1","title":"Synthesis and crystal structure of 4-(2-chlorophenylamino)-6-methoxy-2-phenylquinazoline","year":2011,"lang":"en","type":"article","venue":"Chemistry of Heterocyclic Compounds","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Science North","funders":"","keywords":"Chemistry; Thiourea; Crystal structure; Mass spectrometry; Proton NMR; Crystallography; Stereochemistry; Organic chemistry; Chromatography","score_opus":0.01844181136082906,"score_gpt":0.23051909414385166,"score_spread":0.2120772827830226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971903915","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9760036,0.00033774253,0.00010581251,0.000022931048,0.000021945609,0.00005534316,0.00020623751,0.000054556942,0.023191862],"genre_scores_gemma":[0.995993,0.000060835475,0.0035254806,0.00000722062,0.000099873425,0.000019262654,0.00002470868,0.00003950542,0.00023007643],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982698,0.000013794623,0.0006899561,0.0004575343,0.0002613762,0.0003075533],"domain_scores_gemma":[0.998298,0.00022475644,0.00045284032,0.0007686379,0.00010224275,0.00015353768],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006109568,0.00032327446,0.0006200473,0.000041277784,0.00008806848,0.000013052128,0.00045593551,0.0002339456,0.0028396163],"category_scores_gemma":[0.000093230934,0.00031751322,0.00018133571,0.00011100965,0.00047579795,0.00007484342,0.00018460266,0.0002095312,0.0000017249073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006872104,0.00020710546,0.0021597259,0.0008108587,0.00009023828,0.0000019422694,0.00028438016,8.4981485e-7,0.99392605,0.000071084214,0.00004542738,0.0023336348],"study_design_scores_gemma":[0.00033208547,0.000013542851,0.0016914203,0.0001275621,0.00010415136,0.00007669418,0.0002831546,0.000053359458,0.9953003,0.00091201894,0.0008201848,0.0002855372],"about_ca_topic_score_codex":0.00007325698,"about_ca_topic_score_gemma":0.0000038438116,"teacher_disagreement_score":0.022961786,"about_ca_system_score_codex":0.000031100135,"about_ca_system_score_gemma":0.000020836362,"threshold_uncertainty_score":0.9999277},"labels":[],"label_agreement":null},{"id":"W1976410612","doi":"10.5539/ijc.v2n1p108","title":"Synthesis of 2-Amino-5-aryl-5,6-dihydro-7-(naphthalen-2-yl) Quinazolin-4-ols","year":2010,"lang":"en","type":"article","venue":"International Journal of Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Indian Institute of Science","keywords":"Chemistry; Aryl; Guanidine; Condensation; Combinatorial chemistry; Stereochemistry; Medicinal chemistry; Organic chemistry","score_opus":0.007525287012516626,"score_gpt":0.25928058891266564,"score_spread":0.251755301900149,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976410612","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.956755,0.00011118802,0.00006809206,0.0007928451,0.00030961412,0.000025639163,0.00011430903,0.000020962487,0.041802377],"genre_scores_gemma":[0.9966533,0.00010017769,0.00091799384,0.000031926273,0.0014275889,0.000013465284,0.000011276753,0.000033333192,0.0008109396],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977199,0.000007148189,0.0010055426,0.00022567682,0.00081619143,0.00022554846],"domain_scores_gemma":[0.99704,0.00042388853,0.0011300952,0.00042225362,0.00080112286,0.00018267833],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00031904556,0.00022828672,0.000402696,0.00008304686,0.000047816837,0.00005164603,0.0013489276,0.00023811632,0.005809441],"category_scores_gemma":[0.0006595502,0.00021335574,0.00040494464,0.00008692265,0.00019629384,0.00017873282,0.000115524075,0.0006174293,0.000024626097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000082809514,0.00038520756,0.0025609161,0.00007763698,0.0002489397,0.000047811187,0.000053668104,0.000015960843,0.9869791,0.0002353279,0.00065565866,0.008656938],"study_design_scores_gemma":[0.00043925463,0.0000075827475,0.00059186225,0.0001844511,0.00006973352,0.0007121601,0.00012271307,0.000059026013,0.9849058,0.000809951,0.011902349,0.00019516006],"about_ca_topic_score_codex":0.000015754938,"about_ca_topic_score_gemma":0.000002442901,"teacher_disagreement_score":0.04099144,"about_ca_system_score_codex":0.0000658473,"about_ca_system_score_gemma":0.00019863817,"threshold_uncertainty_score":0.99509937},"labels":[],"label_agreement":null},{"id":"W1978750894","doi":"10.1016/s0960-894x(00)00493-5","title":"Inhibitors of Src tyrosine kinase: the preparation and structure–activity relationship of 4-anilino-3-cyanoquinolines and 4-anilinoquinazolines","year":2000,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Proto-oncogene tyrosine-protein kinase Src; Chemistry; Tyrosine kinase; Angiogenesis; Receptor tyrosine kinase; Tyrosine-protein kinase CSK; Kinase; Cancer research; Signal transduction; Tyrosine-kinase inhibitor; Platelet-derived growth factor receptor; Tyrosine; Protein-Tyrosine Kinases; Structure–activity relationship; Biochemistry; Cell biology; Receptor; In vitro; Internal medicine; Cancer; Growth factor; Biology; Medicine","score_opus":0.009813187631309573,"score_gpt":0.23432703643947053,"score_spread":0.22451384880816097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978750894","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956847,0.0009138713,0.000021782927,0.0026398657,0.000024690175,0.00012094581,0.00007642004,0.000035860896,0.00048186543],"genre_scores_gemma":[0.99899673,0.00015458305,0.00012861537,0.00009776119,0.00040156502,0.000012361371,0.00003446823,0.000024245357,0.0001496645],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985174,0.000026548925,0.00052251905,0.0003906517,0.00032772485,0.00021513975],"domain_scores_gemma":[0.99874383,0.0002742987,0.00032274527,0.00047765503,0.00008252337,0.00009896444],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017768083,0.00025688388,0.00035412313,0.000027275693,0.00015619061,0.000017581335,0.00020372529,0.00017833199,0.0006355154],"category_scores_gemma":[0.00015450461,0.00019689639,0.000065582004,0.00020524951,0.0006186516,0.00008904745,0.000048543916,0.00025640338,0.0000014469374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009287109,0.000058278336,0.0056858473,0.00032732065,0.00003363939,0.0000012144534,0.00025150564,0.0000068094446,0.98960954,0.000035671594,0.00023780606,0.003659482],"study_design_scores_gemma":[0.0004649821,0.000017005565,0.015521054,0.00012657001,0.00014397828,0.000050416475,0.00014687462,0.0001420556,0.98246497,0.00010075407,0.0006395999,0.00018173961],"about_ca_topic_score_codex":0.00006760826,"about_ca_topic_score_gemma":0.0000069749026,"teacher_disagreement_score":0.009835207,"about_ca_system_score_codex":0.00003462913,"about_ca_system_score_gemma":0.000057112487,"threshold_uncertainty_score":0.80292016},"labels":[],"label_agreement":null},{"id":"W1981358324","doi":"10.1107/s0108270100008349","title":"The antifolate trimetrexate: observation of the enzyme-binding conformation","year":2000,"lang":"en","type":"article","venue":"Acta Crystallographica Section C Crystal Structure Communications","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Quinazoline; Hydrogen bond; Molecule; Dimethyl sulfoxide; Chemistry; Crystal structure; Stereochemistry; Sulfoxide; Crystallography; Organic chemistry","score_opus":0.01657059369976385,"score_gpt":0.2404648972225852,"score_spread":0.22389430352282136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981358324","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9850583,0.00038480965,0.00010827023,0.0032058058,0.0001239323,0.00035678124,0.00022533939,0.0001450018,0.010391759],"genre_scores_gemma":[0.9971443,0.001383549,0.00035299908,0.000050296643,0.00008495724,0.000072963434,0.00020768271,0.000029926829,0.00067331875],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99818873,0.00014206613,0.00075531163,0.00025029364,0.00036698417,0.0002965895],"domain_scores_gemma":[0.99617565,0.0005184395,0.00055825675,0.0024522634,0.00022540042,0.000069991205],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.00028367646,0.00024299348,0.00022057588,0.00009475545,0.0023625097,0.00012094332,0.001633532,0.00023007696,0.000884224],"category_scores_gemma":[0.00011733081,0.00016384844,0.00027372883,0.0012051028,0.00059859623,0.0003284705,0.0001992397,0.0005813504,0.0000010999125],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003499977,0.00007423339,0.0016138979,0.000030099387,0.0001025319,4.007548e-8,0.0003165193,0.00009810522,0.98556423,0.0017159226,0.00078453636,0.009664908],"study_design_scores_gemma":[0.00051914464,0.00002129607,0.021650285,0.00007667788,0.00013913112,0.000033156102,0.0007602956,0.0021445625,0.025009764,0.002928976,0.9463687,0.00034804785],"about_ca_topic_score_codex":0.00015161243,"about_ca_topic_score_gemma":0.00043111542,"teacher_disagreement_score":0.9605544,"about_ca_system_score_codex":0.00007933893,"about_ca_system_score_gemma":0.00008044256,"threshold_uncertainty_score":0.9989363},"labels":[],"label_agreement":null},{"id":"W1983523083","doi":"10.1371/journal.pone.0117215","title":"Target Modulation by a Kinase Inhibitor Engineered to Induce a Tandem Blockade of the Epidermal Growth Factor Receptor (EGFR) and c-Src: The Concept of Type III Combi-Targeting","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Regional Health Centre; Royal Victoria Hospital","funders":"Canadian Institutes of Health Research; Servier; McGill University Health Centre; McGill University","keywords":"Proto-oncogene tyrosine-protein kinase Src; Dasatinib; Kinase; Cancer research; Tyrosine kinase; Cell biology; Chemistry; Phosphorylation; EGFR inhibitors; SH3 domain; Tyrosine-kinase inhibitor; Epidermal growth factor receptor; Biology; Signal transduction; Biochemistry; Receptor; Cancer","score_opus":0.03186594421063559,"score_gpt":0.2232635314270348,"score_spread":0.1913975872163992,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983523083","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974772,0.000284449,0.000068992274,0.001547257,0.000023071765,0.00024073888,0.00014654077,0.000024824209,0.00018697487],"genre_scores_gemma":[0.9987311,0.000007943034,0.00082553946,0.00005063212,0.00012133823,0.000035503963,0.000027123686,0.000020345971,0.00018050683],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900055,0.000039372793,0.00032801487,0.00018186416,0.00029118796,0.0001590012],"domain_scores_gemma":[0.9990459,0.00015952364,0.00019424976,0.0002784764,0.00022207545,0.00009977686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014391755,0.00012924972,0.00025174944,0.000018725668,0.000073792195,0.000012414093,0.00019952585,0.00009374468,0.00010202739],"category_scores_gemma":[0.0005345955,0.00008965554,0.000040259987,0.00017876325,0.00008324547,0.00004917878,0.0000915439,0.00015113244,0.0000034917714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022981241,0.00035703531,0.003316048,0.00003936216,0.00006354997,5.5279237e-8,0.0012420162,0.000021085147,0.9929258,0.0001365051,0.0017646289,0.00011092365],"study_design_scores_gemma":[0.00040257274,0.00002896507,0.00066353177,0.00009577828,0.000040375184,2.590001e-7,0.00034077404,0.0011588455,0.9965338,0.00010570369,0.0005187542,0.00011064296],"about_ca_topic_score_codex":0.0000667348,"about_ca_topic_score_gemma":0.0000015138716,"teacher_disagreement_score":0.0036079886,"about_ca_system_score_codex":0.00003808633,"about_ca_system_score_gemma":0.00005158013,"threshold_uncertainty_score":0.3656047},"labels":[],"label_agreement":null},{"id":"W1992682053","doi":"10.1080/10426500490429527","title":"THE SYNTHESIS OF 2,5-DIHYDROXYBENZO-1,3,2-DITHIAZOLYLIUM AND 2,7-DICARBONYL NAPHTHA-1,3,2-DITHIAZOLYLIUM CATIONS","year":2004,"lang":"en","type":"article","venue":"Phosphorus, sulfur, and silicon and the related elements","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick","funders":"","keywords":"Naphtha; Chemistry; Medicinal chemistry; Organic chemistry; Catalysis","score_opus":0.004975250409122907,"score_gpt":0.21153550173357633,"score_spread":0.2065602513244534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992682053","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97248906,0.013868407,0.000006355164,0.0035091718,0.000090036316,0.000359398,0.000079013895,0.000070266186,0.009528303],"genre_scores_gemma":[0.9791275,0.019714538,0.00004881334,0.00009991742,0.000051177198,0.00020332921,0.00001520851,0.00003879661,0.0007006878],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978689,0.000060065027,0.000786704,0.00049584254,0.00032759496,0.00046086963],"domain_scores_gemma":[0.9979102,0.0007768465,0.0003769113,0.00065301976,0.0000821293,0.0002008825],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072512607,0.00034555624,0.00045513015,0.000055049903,0.0010351393,0.00012589141,0.00033413625,0.00021367893,0.000106669766],"category_scores_gemma":[0.00020934507,0.0002177311,0.00012235389,0.00019765843,0.0010442385,0.00010450194,0.00018690403,0.00037207676,0.000012236908],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014327164,0.0016358342,0.028250832,0.0006949353,0.00362769,0.000019729114,0.008882019,0.00007303536,0.18525137,0.5547713,0.0013346011,0.21402593],"study_design_scores_gemma":[0.01534603,0.00016358806,0.022451717,0.00075560634,0.0017316339,0.00022324572,0.006769483,0.0022790863,0.8211691,0.07994025,0.047326338,0.0018439582],"about_ca_topic_score_codex":0.0006451257,"about_ca_topic_score_gemma":0.000048705293,"teacher_disagreement_score":0.63591766,"about_ca_system_score_codex":0.00003942378,"about_ca_system_score_gemma":0.000074623735,"threshold_uncertainty_score":0.88788164},"labels":[],"label_agreement":null},{"id":"W1992700638","doi":"10.1186/cc14014","title":"Inhibitory effects of evodiamine on zymosan-induced inflammation: inactivation of NF-κB by inhibiting IκBα phosphorylation","year":2014,"lang":"en","type":"article","venue":"Critical Care","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Children's Health Foundation; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina; Financiadora de Estudos e Projetos; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Japan Society for the Promotion of Science; Russian Foundation for Basic Research; London Health Sciences Centre","keywords":"Evodiamine; Medicine; Inflammation; Zymosan; Pharmacology; Anti-inflammatory; Drug; Immunology; Proinflammatory cytokine; Biochemistry; In vitro; Biology","score_opus":0.008223433368578906,"score_gpt":0.25203960906640643,"score_spread":0.24381617569782754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992700638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98535067,0.0001202844,0.0005604532,0.00022487182,0.00004856149,0.00010975791,0.000022830804,0.000045218523,0.013517343],"genre_scores_gemma":[0.9993564,0.0000025244847,0.00017869059,0.00002410618,0.00023630886,0.000059694557,0.00009584878,0.000021625901,0.000024815363],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988842,0.00003897482,0.0003974697,0.0002342763,0.00028548026,0.00015960187],"domain_scores_gemma":[0.9982413,0.00098027,0.00014248787,0.00025556,0.0003107544,0.000069602844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010119518,0.00014119419,0.00023322491,0.000046145477,0.00008449045,0.00001360575,0.00009349366,0.00016734056,0.00007682013],"category_scores_gemma":[0.0015271328,0.00014670186,0.000074040225,0.00012235783,0.00008926796,0.0001031023,0.000030335112,0.00015944314,0.000010303641],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016739066,0.00006966454,0.00019064458,0.0012057388,0.0000050385224,2.8905544e-7,0.00027929916,0.0000044011017,0.9607818,0.012558573,0.00008801971,0.024799755],"study_design_scores_gemma":[0.00033066666,0.00007836259,0.0003662293,0.00038104499,0.00003109919,4.693866e-7,0.00053882133,0.00020649639,0.9971247,0.00042618526,0.00037798012,0.0001379461],"about_ca_topic_score_codex":0.000016421714,"about_ca_topic_score_gemma":0.0000014037482,"teacher_disagreement_score":0.036342863,"about_ca_system_score_codex":0.00007673874,"about_ca_system_score_gemma":0.000027592367,"threshold_uncertainty_score":0.5982328},"labels":[],"label_agreement":null},{"id":"W1993506252","doi":"10.1139/v08-149","title":"Solvent-free syntheses of some quinazolin-4(3H)-ones derivatives","year":2008,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Formamide; Benzamide; Quinazolinone; Solvent; Nicotinamide; Proton NMR; Carbon-13 NMR; Antioxidant; Organic chemistry; Montmorillonite; Nuclear chemistry","score_opus":0.02298864262090929,"score_gpt":0.22081091774627046,"score_spread":0.19782227512536116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993506252","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9788275,0.0019501339,0.000028606995,0.0007230033,0.000047740792,0.000024329845,0.0001264739,0.00001014482,0.018262073],"genre_scores_gemma":[0.9978692,0.00019725866,0.0003794587,0.000038099515,0.0004821289,0.0000054156453,0.000004935005,0.000029232302,0.0009942559],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986116,0.00000953191,0.00062646746,0.00016618366,0.00023939008,0.0003467793],"domain_scores_gemma":[0.99787015,0.00017720701,0.00056863704,0.0005391614,0.00026546486,0.0005793721],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011581917,0.00019715242,0.00040769816,0.00007000448,0.00018383966,0.000020162264,0.0008096431,0.00015725332,0.002171839],"category_scores_gemma":[0.0007300578,0.00019180929,0.00024205806,0.000118822754,0.00042275412,0.00015760463,0.000031733805,0.00028356956,0.0000075043067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021821676,0.000098300865,0.005934996,0.000260941,0.00013842987,0.00016278347,0.000598587,0.000026581622,0.9862123,0.0002665513,0.0053206873,0.0009579936],"study_design_scores_gemma":[0.0002675635,0.000010897719,0.00080813025,0.00025583914,0.000034751512,0.0005288028,0.00066711043,0.0000059190056,0.98244226,0.0010500232,0.013723154,0.00020554144],"about_ca_topic_score_codex":0.00045043993,"about_ca_topic_score_gemma":0.00018711435,"teacher_disagreement_score":0.019041723,"about_ca_system_score_codex":0.00011082124,"about_ca_system_score_gemma":0.0014246383,"threshold_uncertainty_score":0.9987403},"labels":[],"label_agreement":null},{"id":"W1993560396","doi":"10.1021/jm000206a","title":"4-Anilino-6,7-dialkoxyquinoline-3-carbonitrile Inhibitors of Epidermal Growth Factor Receptor Kinase and Their Bioisosteric Relationship to the 4-Anilino-6,7-dialkoxyquinazoline Inhibitors","year":2000,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":209,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Chemistry; Malononitrile; Amidine; Autophosphorylation; Quinoline; Epidermal growth factor; Stereochemistry; Amide; Kinase; Substituent; Protein kinase A; Receptor; Organic chemistry; Catalysis; Biochemistry","score_opus":0.015093823601053026,"score_gpt":0.24010807753307614,"score_spread":0.22501425393202312,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993560396","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904256,0.001998299,0.00004696633,0.0047169644,0.00019799997,0.00017342213,0.00016396343,0.000037440233,0.0022393872],"genre_scores_gemma":[0.9946638,0.0004643297,0.00036689712,0.00021474238,0.0035870413,0.000023480632,0.00002523905,0.00006107904,0.0005934048],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963973,0.00008214842,0.0018362207,0.00043704433,0.0007352717,0.0005120047],"domain_scores_gemma":[0.99641454,0.0009226123,0.0010132957,0.0006009865,0.0004748923,0.0005736741],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007244048,0.0005012902,0.0008676321,0.0001265842,0.0002468038,0.000049659426,0.00068549986,0.0003710126,0.0023167098],"category_scores_gemma":[0.0010135974,0.00034018976,0.00038451323,0.0005391919,0.00037219655,0.00018540228,0.00010929887,0.0010105917,0.000025065647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00056989724,0.00041426072,0.0067447643,0.00047730657,0.00015146735,0.00002296993,0.001406171,0.00004614066,0.9560519,0.00002630364,0.00505452,0.029034328],"study_design_scores_gemma":[0.0013794486,0.00016499734,0.0019554517,0.0006532296,0.00016585899,0.00038150963,0.0013950566,0.00008318028,0.97075343,0.00020038756,0.02243908,0.00042838027],"about_ca_topic_score_codex":0.000050044455,"about_ca_topic_score_gemma":0.0000045259994,"teacher_disagreement_score":0.028605947,"about_ca_system_score_codex":0.00014675183,"about_ca_system_score_gemma":0.0002968196,"threshold_uncertainty_score":0.999905},"labels":[],"label_agreement":null},{"id":"W1999390115","doi":"10.1016/j.bmcl.2012.12.089","title":"Spiro heterocycles as potential inhibitors of SIRT1: Pd/C-mediated synthesis of novel N-indolylmethyl spiroindoline-3,2′-quinazolines","year":2013,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute for Liberal Studies","keywords":"Chemistry; Quinazoline; Stereochemistry; Sulfonyl; Ring (chemistry); Docking (animal); Indoline; Molecule; In vitro; Benzene; Combinatorial chemistry; Biochemistry; Organic chemistry","score_opus":0.008521542327614528,"score_gpt":0.21570208252414455,"score_spread":0.20718054019653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999390115","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99397606,0.00039704153,0.00016800882,0.0038196056,0.00010151754,0.00020788117,0.00013452949,0.00011565368,0.0010797335],"genre_scores_gemma":[0.9975925,0.00011293633,0.00068493374,0.0002588271,0.0009831688,0.000098782206,0.00008236375,0.00008989986,0.00009659067],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99649435,0.000021986825,0.0013187975,0.00069285487,0.00084487576,0.00062713266],"domain_scores_gemma":[0.99722123,0.00041889396,0.0008867546,0.0008897185,0.0002337899,0.00034962935],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022125838,0.00055537943,0.00090223603,0.00008571397,0.00010847672,0.000027053013,0.0007964793,0.00037262915,0.0043811956],"category_scores_gemma":[0.0007386825,0.00050882663,0.00036009436,0.00036098843,0.00064694637,0.00013362065,0.00018093702,0.00041297686,0.00009116801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005449701,0.00049394794,0.0005269789,0.0007290535,0.00014768768,0.000010365623,0.000076438315,0.000009448317,0.9940886,0.000008832442,0.0010539972,0.0028001422],"study_design_scores_gemma":[0.0010482457,0.000018942852,0.0010777338,0.00047438062,0.00021308317,0.000086068416,0.0004898001,0.00014765612,0.99544907,0.000017422335,0.0005291065,0.00044851933],"about_ca_topic_score_codex":0.00039559457,"about_ca_topic_score_gemma":0.0000019137708,"teacher_disagreement_score":0.0042900275,"about_ca_system_score_codex":0.00010913961,"about_ca_system_score_gemma":0.00013813307,"threshold_uncertainty_score":0.9997363},"labels":[],"label_agreement":null},{"id":"W2003392551","doi":"10.1111/cbdd.12402","title":"Positional Isomerization of A Non‐Cleavable Combi‐Molecule Dramatically Altered Tumor Cell Response Profile","year":2014,"lang":"en","type":"article","venue":"Chemical Biology & Drug Design","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Hospital; Royal Victoria Regional Health Centre","funders":"Canadian Institutes of Health Research; Jewish General Hospital; McGill University Health Centre","keywords":"Quinazoline; Potency; Chemistry; Isomerization; Epidermal growth factor receptor; Moiety; DNA damage; Tyrosine kinase; Phosphorylation; DNA synthesis; DNA; Biochemistry; Stereochemistry; Receptor; In vitro","score_opus":0.00756686708993967,"score_gpt":0.22736580414618532,"score_spread":0.21979893705624565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003392551","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9584921,0.000032225784,0.034383807,0.00048076813,0.000023623517,0.0001987898,0.00007114123,0.000074898264,0.006242654],"genre_scores_gemma":[0.98390144,0.0000027718638,0.015057303,0.00019323394,0.00008773376,0.00015408092,0.00019765394,0.000026302183,0.00037949107],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986444,0.00013465741,0.00043909863,0.00037496883,0.0001139036,0.00029293154],"domain_scores_gemma":[0.9983573,0.0008191803,0.00020072547,0.0003975051,0.00011101874,0.00011426036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035274326,0.00018639746,0.0003269274,0.00004187048,0.00007745044,0.000014423437,0.00031946658,0.00015666572,0.00082359766],"category_scores_gemma":[0.00023747084,0.00017415221,0.00010148804,0.00013041453,0.0002680132,0.00003562516,0.00006882581,0.00016489912,0.00016405208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032434912,0.0003413365,0.000075005926,0.00006126539,0.000016557746,4.631785e-7,0.000054578526,0.0000075974162,0.9965616,0.0006951561,0.0014594025,0.00040271005],"study_design_scores_gemma":[0.000533369,0.00004492889,0.00009407998,0.0000345702,0.00002951249,0.0000053755243,0.000024032039,0.00424264,0.9925078,0.0015516102,0.00074532826,0.00018674048],"about_ca_topic_score_codex":0.000004778316,"about_ca_topic_score_gemma":5.8572418e-8,"teacher_disagreement_score":0.025409337,"about_ca_system_score_codex":0.000035372053,"about_ca_system_score_gemma":0.00008353889,"threshold_uncertainty_score":0.9017817},"labels":[],"label_agreement":null},{"id":"W2014938747","doi":"10.1016/j.bmc.2007.03.055","title":"Dual irreversible kinase inhibitors: Quinazoline-based inhibitors incorporating two independent reactive centers with each targeting different cysteine residues in the kinase domains of EGFR and VEGFR-2","year":2007,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":75,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Chemistry; Quinazoline; Moiety; Kinase; Cysteine; Enzyme; Stereochemistry; Biochemistry; Docking (animal); Amide","score_opus":0.008816336832880809,"score_gpt":0.23518078924581,"score_spread":0.2263644524129292,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014938747","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99701494,0.00056654675,0.0001712139,0.0006111426,0.000039945025,0.00023369378,0.000040514864,0.000056343128,0.0012656756],"genre_scores_gemma":[0.99867505,0.000016138718,0.0003057192,0.00007133455,0.0006799098,0.00003600715,0.00012871905,0.000050890478,0.000036208614],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970613,0.000053487962,0.00087289256,0.0006404277,0.00082730246,0.00054456934],"domain_scores_gemma":[0.9978405,0.00046381503,0.0007866402,0.0005420539,0.00013355413,0.00023340923],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010103334,0.00045942166,0.00051343587,0.000097093296,0.000204068,0.000034816836,0.0003498823,0.00022402601,0.00007545358],"category_scores_gemma":[0.00028639683,0.0003300158,0.00009203803,0.0004379532,0.00043568405,0.00009420881,0.00012978907,0.0007189234,0.0000016840103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029538182,0.0005048937,0.03558153,0.00047114768,0.000040427305,0.00016324846,0.0007495684,0.0000036941915,0.96128434,0.000033924545,0.000106020816,0.0007658181],"study_design_scores_gemma":[0.0026253813,0.0001025221,0.0042012036,0.0009219956,0.000110168105,0.00006830906,0.011996535,0.000051596908,0.9793732,0.000044396365,0.00014923744,0.00035543603],"about_ca_topic_score_codex":0.00068352546,"about_ca_topic_score_gemma":0.00022550866,"teacher_disagreement_score":0.031380326,"about_ca_system_score_codex":0.00031453202,"about_ca_system_score_gemma":0.00019485672,"threshold_uncertainty_score":0.9999152},"labels":[],"label_agreement":null},{"id":"W2019876671","doi":"10.1021/ol101428v","title":"One-Step Synthesis of Quinazolino[3,2-<i>a</i>]quinazolinones via Palladium-Catalyzed Domino Addition/Carboxamidation Reactions","year":2010,"lang":"en","type":"article","venue":"Organic Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Domino; Chemistry; Palladium; Catalysis; Combinatorial chemistry; Cascade reaction; Functional group; Reaction conditions; Organic chemistry","score_opus":0.008310487006870603,"score_gpt":0.20964181055050218,"score_spread":0.2013313235436316,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019876671","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9895463,0.000022797236,0.0022676855,0.0036673492,0.0002480434,0.00021364774,0.0002262445,0.00026024913,0.0035476862],"genre_scores_gemma":[0.9954277,0.0000561399,0.0029302915,0.00022672802,0.0006980761,0.0002340025,0.00022526944,0.00010248466,0.00009926047],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99750924,0.000041340863,0.0008508686,0.0006386185,0.00045474348,0.00050520437],"domain_scores_gemma":[0.997171,0.00056928204,0.00058977795,0.0013001274,0.00016395637,0.00020585008],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00027147526,0.00037172466,0.00052043167,0.00017751995,0.00029513714,0.00006144872,0.00060103316,0.00030580867,0.0075032567],"category_scores_gemma":[0.00033007577,0.000412139,0.00025583265,0.0004002259,0.00028065147,0.00027712653,0.00010055333,0.00053292484,0.00046079085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032271713,0.00036470944,0.00032566226,0.00013391132,0.000113063696,0.0000026455527,0.000086557586,0.000003404444,0.99039286,0.00089770224,0.000867513,0.0067796675],"study_design_scores_gemma":[0.00048914424,0.0000073705382,0.0023243374,0.00007813492,0.00023224016,0.000032949774,0.00008956545,0.00013550943,0.99063474,0.00017131942,0.005357768,0.00044691385],"about_ca_topic_score_codex":0.00024203637,"about_ca_topic_score_gemma":0.00015388682,"teacher_disagreement_score":0.0070424657,"about_ca_system_score_codex":0.00010879796,"about_ca_system_score_gemma":0.000099584446,"threshold_uncertainty_score":0.99983305},"labels":[],"label_agreement":null},{"id":"W2020235804","doi":"10.1002/chin.201235188","title":"ChemInform Abstract: Palladium‐Catalyzed Intermolecular Cyclocarbonylation of 2‐Iodoanilines with N‐Toluenesulfonyl Aldimines.","year":2012,"lang":"en","type":"article","venue":"ChemInform","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Aldimine; Catalysis; Intermolecular force; Palladium; Organic chemistry; Polymer chemistry; Molecule","score_opus":0.012221572165859578,"score_gpt":0.23132559850500614,"score_spread":0.21910402633914655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020235804","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4426713,0.0002200277,0.000004141789,0.000048479276,0.000028195214,0.00010041895,0.000023640334,0.000084158935,0.5568196],"genre_scores_gemma":[0.9952147,0.000040321112,0.00012913407,0.000030903673,0.00024234915,0.000095321746,0.00028670864,0.000042905434,0.003917653],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984024,4.843717e-8,0.0005986959,0.00021581416,0.0003299116,0.0004530961],"domain_scores_gemma":[0.99847394,0.00007437435,0.00042095938,0.0006692141,0.00015719986,0.0002042856],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014814848,0.00030754576,0.00035369332,0.00006517934,0.00006737138,0.00002557253,0.0003268548,0.00019635787,0.0015963885],"category_scores_gemma":[0.00006993208,0.0002585603,0.00014272112,0.00020069796,0.00015091483,0.00035273004,0.00007795051,0.00016080626,0.000053757787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020947258,0.0005051597,0.006408199,0.0011687031,0.00025003287,0.0000042091906,0.0015374728,0.00000271273,0.57522285,0.0010541162,0.0022220698,0.411415],"study_design_scores_gemma":[0.00051444926,0.000007594706,0.0049515776,0.00011666706,0.00007912941,0.00003246474,0.0002797041,0.000018604713,0.9809288,0.00002186573,0.012713681,0.00033549868],"about_ca_topic_score_codex":0.0000352336,"about_ca_topic_score_gemma":0.0000058574938,"teacher_disagreement_score":0.552902,"about_ca_system_score_codex":0.000081564904,"about_ca_system_score_gemma":0.0000711488,"threshold_uncertainty_score":0.99998665},"labels":[],"label_agreement":null},{"id":"W2026260646","doi":"10.1016/j.cbi.2010.11.008","title":"Proliferative and androgenic effects of indirubin derivatives in LNCaP human prostate cancer cells at sub-apoptotic concentrations","year":2010,"lang":"en","type":"article","venue":"Chemico-Biological Interactions","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"LNCaP; Apoptosis; Indirubin; Prostate cancer; Cancer research; Prostate; Cancer; Cancer cell; Chemistry; Internal medicine; Endocrinology; Medicine; Biochemistry; Physics","score_opus":0.013770870977164429,"score_gpt":0.2832644101507008,"score_spread":0.26949353917353636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026260646","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998219,0.00012687854,0.0000046016867,0.0001565245,0.000057269088,0.00029153374,0.00008554041,0.00004010537,0.0010185576],"genre_scores_gemma":[0.99869215,0.0001343656,0.00010980056,0.000039900748,0.00006403014,0.0006079181,0.00006514157,0.000012572099,0.00027413058],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989601,0.000023630351,0.0003585883,0.0003552104,0.00006601878,0.00023646229],"domain_scores_gemma":[0.9990255,0.00041551288,0.00019310167,0.0002012476,0.0000720801,0.00009252378],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000047761525,0.00018683003,0.000275486,0.0000437408,0.00017090813,0.000023362532,0.00012855507,0.00014960075,0.0006489177],"category_scores_gemma":[0.0001163251,0.0001533718,0.000065521985,0.00012765394,0.00035781832,0.00009598072,0.000087595814,0.0004264054,0.000009446378],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020191546,0.0002747904,0.019371744,0.000063637,0.00003019172,0.0000013577838,0.00066435774,0.0000024760482,0.9786458,0.0006202487,0.00009253017,0.00021265245],"study_design_scores_gemma":[0.00036080444,0.000022552347,0.008690197,0.00007423474,0.000021603504,0.000007495534,0.00018940303,0.000035821395,0.98958486,0.00043443384,0.00041132278,0.00016724502],"about_ca_topic_score_codex":0.000036066253,"about_ca_topic_score_gemma":0.00016277362,"teacher_disagreement_score":0.0109390635,"about_ca_system_score_codex":0.00007015253,"about_ca_system_score_gemma":0.000030793617,"threshold_uncertainty_score":0.7105194},"labels":[],"label_agreement":null},{"id":"W2026296430","doi":"10.1002/chin.201019159","title":"ChemInform Abstract: Mild and Efficient Ligand‐Free Copper‐Catalyzed Condensation for the Synthesis of Quinazolines.","year":2010,"lang":"en","type":"article","venue":"ChemInform","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Chemistry; Condensation; Combinatorial chemistry; Ligand (biochemistry); Copper; Service (business); Catalysis; Organic chemistry; Business; Receptor; Thermodynamics","score_opus":0.014208616100069698,"score_gpt":0.2447940122114837,"score_spread":0.230585396111414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026296430","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7477484,0.00014661322,0.0000014174705,0.00073533645,0.000081600956,0.00035981133,0.00027712906,0.00007151279,0.2505782],"genre_scores_gemma":[0.9969324,0.00005471329,0.00009758898,0.00003278692,0.00020139423,0.0003836274,0.00004870633,0.000025899404,0.0022229045],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876845,2.8892696e-8,0.0005046385,0.00022610492,0.00022210686,0.00027868978],"domain_scores_gemma":[0.997656,0.00092826074,0.00032728162,0.00081208657,0.00017382001,0.000102571634],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028597962,0.00021964197,0.00028164923,0.00003694802,0.00020147602,0.00004712836,0.00047429712,0.000217054,0.00044770772],"category_scores_gemma":[0.0006016968,0.00016166738,0.00014728811,0.000093819865,0.00027796585,0.000080376936,0.000109914465,0.00020351968,0.000012228852],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000064505206,0.0001265191,0.00006481728,0.000544703,0.0000780312,1.9342558e-7,0.0005575222,0.0000011518533,0.703342,0.0024975073,0.005954515,0.2867685],"study_design_scores_gemma":[0.00051059725,0.0000038276075,0.000510699,0.000047191606,0.000095579635,0.000009176031,0.00068193383,0.00024600458,0.97924787,0.0001298708,0.018318778,0.00019848661],"about_ca_topic_score_codex":0.000043034517,"about_ca_topic_score_gemma":0.000024035187,"teacher_disagreement_score":0.28657,"about_ca_system_score_codex":0.000026777467,"about_ca_system_score_gemma":0.00007415056,"threshold_uncertainty_score":0.65926045},"labels":[],"label_agreement":null},{"id":"W2028012039","doi":"10.1002/jlcr.713","title":"Synthesis of 1‐[4‐(m‐tolyl)amino‐6‐quinazolinyl]‐3‐[<sup>14</sup>C]‐methyl triazene: a radiolabeled probe for the combi‐targeting concept","year":2003,"lang":"en","type":"article","venue":"Journal of Labelled Compounds and Radiopharmaceuticals","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital; Royal Victoria Hospital; Royal Victoria Regional Health Centre","funders":"Canadian Institutes of Health Research; Cancer Research Society","keywords":"Triazene; Chemistry; Alkylation; Hydrolysis; Liquid scintillation counting; Quinazoline; Stereochemistry; Nuclear chemistry; Radiochemistry; Biochemistry; Organic chemistry","score_opus":0.028283655054100135,"score_gpt":0.30465026132092426,"score_spread":0.27636660626682413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2028012039","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92557955,0.05646008,0.007906098,0.004320238,0.0004187595,0.0013141282,0.00019475256,0.00007615623,0.0037302175],"genre_scores_gemma":[0.9893529,0.0031356914,0.0064284964,0.00016121176,0.00042279254,0.00010113623,0.0000035337353,0.00006568667,0.00032855774],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99641794,0.00025788014,0.0018006287,0.00037736504,0.0005385339,0.0006076422],"domain_scores_gemma":[0.9914413,0.006004603,0.0011938495,0.00043992302,0.0005605446,0.0003597755],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0024706898,0.00043110648,0.0013149536,0.00013785355,0.0005795476,0.000115414914,0.00064952835,0.00024376257,0.00030493],"category_scores_gemma":[0.0014124403,0.0002923146,0.0005469322,0.00032684466,0.00050864543,0.0001546535,0.000066963825,0.0006275496,0.000002837786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016337072,0.004124968,0.00092398346,0.0010919203,0.002863562,0.0000361592,0.001663296,0.00052094215,0.9235002,0.026887508,0.007304287,0.029449496],"study_design_scores_gemma":[0.015500767,0.00023843953,0.00003460849,0.00039194463,0.0018625549,0.0004489649,0.0014190548,0.012425871,0.8150347,0.002346931,0.14964052,0.0006556293],"about_ca_topic_score_codex":0.000004945926,"about_ca_topic_score_gemma":2.8929992e-7,"teacher_disagreement_score":0.14233623,"about_ca_system_score_codex":0.00008472619,"about_ca_system_score_gemma":0.00024132412,"threshold_uncertainty_score":0.9999529},"labels":[],"label_agreement":null},{"id":"W2028243349","doi":"10.1021/ol7029454","title":"Palladium-Catalyzed Cyclocarbonylation of <i>o</i>-Iodoanilines with Imidoyl Chlorides to Produce Quinazolin-4(<i>3H</i>)-ones","year":2008,"lang":"en","type":"article","venue":"Organic Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":125,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Catalysis; Intramolecular force; Palladium; Carbon monoxide; Oxidative phosphorylation; Medicinal chemistry; Combinatorial chemistry; Carbonylation; Organic chemistry; Biochemistry","score_opus":0.01071545734773019,"score_gpt":0.2022983179686323,"score_spread":0.1915828606209021,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2028243349","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926235,0.00007748177,0.00055662956,0.0058713835,0.000050596653,0.00021333879,0.000021487807,0.00015237664,0.00043321896],"genre_scores_gemma":[0.9975724,0.00004389182,0.0010625737,0.0005603622,0.00042000232,0.000075865806,0.000046428915,0.00007341024,0.00014504541],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983,0.00001017061,0.00043951804,0.0005310965,0.0003606134,0.000358574],"domain_scores_gemma":[0.99864644,0.00008995764,0.00022282629,0.00077882,0.00011996665,0.00014201875],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010379741,0.00028849786,0.00037071094,0.00008713361,0.00017054437,0.00001987227,0.00035835433,0.00008341499,0.00030124094],"category_scores_gemma":[0.00008015594,0.00024903135,0.0000845742,0.00045015023,0.00014952067,0.00012344203,0.000067251494,0.00014454097,0.000097056756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007820498,0.00012252884,0.010521345,0.00008297133,0.000054091965,0.000011207021,0.00047020067,0.00006649445,0.9873207,0.000041416755,0.0008611216,0.00036968008],"study_design_scores_gemma":[0.0004583263,0.0000195428,0.007980154,0.00006454558,0.00005827796,0.00006776879,0.000075641,0.000019390032,0.9898339,0.000012181167,0.0010821638,0.00032811618],"about_ca_topic_score_codex":0.000087904395,"about_ca_topic_score_gemma":0.00004873364,"teacher_disagreement_score":0.0053110216,"about_ca_system_score_codex":0.00007197876,"about_ca_system_score_gemma":0.00009853541,"threshold_uncertainty_score":0.9999962},"labels":[],"label_agreement":null},{"id":"W2030959305","doi":"10.5539/gjhs.v4n1p174","title":"Reactivity of 2-Ethoxyquinazolin- 4-yl hydrazine and its Use in Synthesis of Novel Quinazoline Derivatives of Antimicrobial Activity","year":2011,"lang":"en","type":"article","venue":"Global Journal of Health Science","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Triethyl orthoformate; Quinazoline; Ethyl chloroformate; Ethyl chloroacetate; Medicinal chemistry; Antimicrobial; Organic chemistry; Chloride; Hydrazine (antidepressant); Hydrate; Chromatography","score_opus":0.06789060046844682,"score_gpt":0.32743489018122246,"score_spread":0.25954428971277566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030959305","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986075,0.00013289673,0.00041590972,0.00019670966,0.00003843328,0.000086003936,0.00013042947,0.000004084795,0.00038800488],"genre_scores_gemma":[0.993102,0.0003019533,0.0065526534,0.000013526924,0.000019769193,0.0000017406652,2.2868143e-7,0.0000060446646,0.0000020421867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978869,0.000043299286,0.0010275781,0.00025567392,0.00044761947,0.00033890913],"domain_scores_gemma":[0.9967682,0.00022623055,0.0020768396,0.00027736992,0.00048851274,0.00016284922],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001597673,0.00015774496,0.00072018115,0.0001683185,0.00008233774,0.000009697372,0.00048237096,0.000075716554,0.000018647128],"category_scores_gemma":[0.00082847656,0.00013846642,0.000092414244,0.00069754274,0.0006861232,0.0006099621,0.00014003443,0.00018603778,2.5446772e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022158829,0.0013138376,0.037630662,0.00032351053,0.000013290997,0.0000019118463,0.00016226828,0.00002157772,0.94977045,0.000782121,0.0000056524814,0.009753143],"study_design_scores_gemma":[0.00036317267,0.00006885252,0.27924523,0.00043711896,0.000013798762,0.000080761885,0.00006965831,0.0001591321,0.71940506,0.00006648187,0.0000099436575,0.00008076745],"about_ca_topic_score_codex":0.00084415404,"about_ca_topic_score_gemma":0.000064735126,"teacher_disagreement_score":0.24161457,"about_ca_system_score_codex":0.0001269551,"about_ca_system_score_gemma":0.0007607127,"threshold_uncertainty_score":0.5646497},"labels":[],"label_agreement":null},{"id":"W2038291815","doi":"10.1016/j.bbrc.2011.02.018","title":"2-BFI attenuates experimental autoimmune encephalomyelitis-induced spinal cord injury with enhanced B-CK, CaATPase, but reduced calpain activity","year":2011,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; Institute for Biological Sciences","funders":"National Natural Science Foundation of China","keywords":"Calpain; Spinal cord; Experimental autoimmune encephalomyelitis; Multiple sclerosis; Medicine; Spinal cord injury; Pharmacology; Encephalomyelitis; Myelin basic protein; Immunology; Internal medicine; Myelin; Endocrinology; Central nervous system; Chemistry; Biochemistry; Enzyme","score_opus":0.12298607111143586,"score_gpt":0.38183339086674933,"score_spread":0.2588473197553135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038291815","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909753,0.00041537656,0.000028325752,0.000955602,0.0000095017995,0.00026253032,0.00009352227,0.000116421164,0.007143379],"genre_scores_gemma":[0.99679095,0.00024537172,0.0017309448,0.000022468967,0.000111782574,0.00069779233,0.00006261341,0.00003508267,0.00030301994],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99772865,0.00016648114,0.00031992927,0.00062133704,0.00052646693,0.00063711125],"domain_scores_gemma":[0.9970271,0.00037152838,0.00010777222,0.0018290363,0.00029400826,0.0003705708],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002911052,0.0002886005,0.00034345486,0.0000805689,0.00073699554,0.00008236274,0.0011849605,0.00020087414,0.00025766616],"category_scores_gemma":[0.00018507091,0.00023920693,0.00010843033,0.00046608152,0.0016423775,0.00015031046,0.00073630933,0.000903064,0.00007268688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007463436,0.0014824893,0.000016343469,0.000034925175,0.0000422716,0.0000018450967,0.00013584418,4.5838284e-9,0.9709906,0.0025942333,0.000116230214,0.0238389],"study_design_scores_gemma":[0.0003318583,0.00051634357,0.0027575712,0.00013404209,0.000020899124,0.0000057048196,0.0005959189,0.00009914677,0.9941859,0.00041358586,0.00061353896,0.000325488],"about_ca_topic_score_codex":0.0010476685,"about_ca_topic_score_gemma":0.0000117820855,"teacher_disagreement_score":0.023513412,"about_ca_system_score_codex":0.00012960561,"about_ca_system_score_gemma":0.00017297346,"threshold_uncertainty_score":0.97545755},"labels":[],"label_agreement":null},{"id":"W2040208917","doi":"10.1002/chin.200033152","title":"ChemInform Abstract: Palladium‐Catalyzed Cyclocarbonylation of o‐Iodoanilines with Heterocumulenes: Regioselective Preparation of 4(3H)‐Quinazolinone Derivatives.","year":2000,"lang":"en","type":"article","venue":"ChemInform","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Regioselectivity; Quinazolinone; Palladium; Catalysis; Combinatorial chemistry; Organic chemistry","score_opus":0.012138305573210984,"score_gpt":0.252168535104811,"score_spread":0.24003022953160003,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040208917","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.58844393,0.00008239769,0.0000036199142,0.000028297214,0.000005670653,0.00016708169,0.00002973268,0.00005653863,0.41118276],"genre_scores_gemma":[0.99310714,0.00016673714,0.00016954324,0.000013011209,0.00009328902,0.00012457253,0.00028878127,0.00003495209,0.0060019507],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99813914,1.6015991e-7,0.00084229984,0.00032926004,0.00038214977,0.00030697658],"domain_scores_gemma":[0.99816793,0.0001266836,0.00067203,0.0006185751,0.00031167816,0.00010311941],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011485502,0.0003213715,0.0004869557,0.00007543334,0.00008161378,0.000020439827,0.00029741685,0.00021955254,0.002392486],"category_scores_gemma":[0.00005361018,0.00028387803,0.00014262185,0.00032970187,0.00024074738,0.00039194754,0.000030257814,0.00015355734,0.000019745248],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001571942,0.0007033175,0.0012900733,0.001386872,0.00036597752,0.0000025297861,0.004675161,0.0000778976,0.49362737,0.0004072406,0.0007633321,0.49512827],"study_design_scores_gemma":[0.0008285484,0.00005123141,0.0036249328,0.00018603628,0.000068406734,0.000014715586,0.00033002262,0.000110951034,0.9922897,0.000103827086,0.0020827116,0.00030886533],"about_ca_topic_score_codex":0.00007406597,"about_ca_topic_score_gemma":0.000026041062,"teacher_disagreement_score":0.49866238,"about_ca_system_score_codex":0.00010082178,"about_ca_system_score_gemma":0.0001416726,"threshold_uncertainty_score":0.9999613},"labels":[],"label_agreement":null},{"id":"W2040996880","doi":"10.1016/j.ejmech.2013.03.062","title":"In vitro biosynthesis, isolation, and identification of predominant metabolites of 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one (RVX-208)","year":2013,"lang":"en","type":"article","venue":"European Journal of Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Resverlogix (Canada); NAEJA-RGM Pharmaceuticals (Canada)","funders":"","keywords":"Chemistry; Glycosidic bond; Microsome; Metabolite; Glucuronic acid; Stereochemistry; Glucuronidation; Yield (engineering); UGT2B7; Anomer; S9 fraction; In vivo; In vitro; Chromatography; Enzyme; Biochemistry","score_opus":0.009976254597819654,"score_gpt":0.23023301238385643,"score_spread":0.2202567577860368,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040996880","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902712,0.0040724464,0.0012931846,0.00062961126,0.000048631442,0.0001083179,0.00003427726,0.000011720855,0.003530605],"genre_scores_gemma":[0.9914488,0.0005678596,0.007210352,0.00002342424,0.00035767196,0.00000734171,0.000009087491,0.000045357,0.0003301109],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99648374,0.00019661932,0.0021597417,0.00031494015,0.000562982,0.00028195072],"domain_scores_gemma":[0.9960966,0.00053959934,0.0021320374,0.0004990782,0.0005173177,0.00021537623],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0023278696,0.0002751075,0.0007907207,0.00015908024,0.000055261597,0.000025443042,0.0005247015,0.000103249105,0.0012275183],"category_scores_gemma":[0.0011007456,0.00024425058,0.00018960587,0.00028389282,0.00036402477,0.00024525574,0.00009320955,0.00044202618,0.000011246875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012976355,0.00031265058,0.00043428704,0.00053795904,0.000098399614,0.000010182199,0.0003864733,0.000009336341,0.9875248,0.000029855972,0.00014303609,0.010383228],"study_design_scores_gemma":[0.0009692336,0.000034687808,0.0041215033,0.00041995785,0.00021011004,0.00011327347,0.00072061876,0.00025957497,0.9917965,0.0004117767,0.00074695447,0.00019579954],"about_ca_topic_score_codex":0.000026577554,"about_ca_topic_score_gemma":1.9217917e-7,"teacher_disagreement_score":0.010187428,"about_ca_system_score_codex":0.000043280746,"about_ca_system_score_gemma":0.00009173286,"threshold_uncertainty_score":0.99968547},"labels":[],"label_agreement":null},{"id":"W2044489946","doi":"10.1002/chin.201423183","title":"ChemInform Abstract: Aminophenylpyrrole Synthesis and Application to Pyrrolo[1,2‐c]quinazolinone Synthesis.","year":2014,"lang":"en","type":"article","venue":"ChemInform","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Quinazolinone; Chemistry; Library science; Citation; Art history; Art; Stereochemistry; Computer science","score_opus":0.007862908413053472,"score_gpt":0.22400541758200965,"score_spread":0.21614250916895617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044489946","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.08787812,0.00006916571,0.000032796364,0.0008763341,0.000031989523,0.00027051786,0.00006991471,0.00034574565,0.9104254],"genre_scores_gemma":[0.9893792,0.000063733656,0.00031895374,0.00033572465,0.00040535117,0.0015704989,0.000042325373,0.00007473121,0.007809458],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99750674,1.7613259e-7,0.0007302104,0.00066565635,0.0004055617,0.00069167477],"domain_scores_gemma":[0.9972099,0.0006798821,0.00031124378,0.0011537513,0.00012808583,0.0005171367],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00041342818,0.0004880622,0.0005598491,0.00012153029,0.000308462,0.00012732069,0.00061647425,0.00035398998,0.0022732634],"category_scores_gemma":[0.0006939087,0.00048297632,0.00015475333,0.00024830998,0.00017243947,0.00026814797,0.00022570974,0.00027169162,0.0007487995],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003813785,0.00010860955,0.00006153241,0.0002652391,0.00003626546,6.2837194e-7,0.00023505732,0.0000014838588,0.095419526,0.0016875298,0.0044356138,0.8977104],"study_design_scores_gemma":[0.00017016164,0.000009743132,0.0012563053,0.00008641461,0.00007202877,0.000016494065,0.00023959171,0.00017071368,0.7782221,0.0002576991,0.21898635,0.0005124444],"about_ca_topic_score_codex":0.00006596818,"about_ca_topic_score_gemma":0.000014414424,"teacher_disagreement_score":0.90261596,"about_ca_system_score_codex":0.0001409163,"about_ca_system_score_gemma":0.000051414878,"threshold_uncertainty_score":0.9997622},"labels":[],"label_agreement":null},{"id":"W2047812593","doi":"10.1039/c3ra41370e","title":"A recyclable CuO-catalyzed synthesis of 4(3H)-quinazolinones","year":2013,"lang":"en","type":"article","venue":"RSC Advances","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Allison University","funders":"","keywords":"Catalysis; Solvent; Tandem; Chemistry; Atmosphere (unit); Atom economy; Combinatorial chemistry; Reaction conditions; Chemical engineering; Organic chemistry; Materials science; Physics; Composite material","score_opus":0.010326459270679236,"score_gpt":0.2460532973276172,"score_spread":0.23572683805693795,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047812593","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8626062,0.0029067046,0.00026874847,0.0006564305,0.00006513845,0.00019262246,0.00007178942,0.00017415712,0.13305816],"genre_scores_gemma":[0.9921164,0.00086419244,0.004028081,0.000019523319,0.00014274548,0.00046908332,0.000011348176,0.000030899035,0.0023177569],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875,0.000013414245,0.000399324,0.0003269003,0.00020670092,0.0003036787],"domain_scores_gemma":[0.9986036,0.00038239337,0.00024083955,0.00056740484,0.00011123911,0.000094564246],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008184735,0.00018894025,0.00034744837,0.000050442075,0.000113067304,0.000027493921,0.00035209718,0.000097177406,0.0047686733],"category_scores_gemma":[0.00017552215,0.00016526281,0.00012113455,0.00017635524,0.00013418011,0.00033552496,0.00006358751,0.00009868209,0.00051034434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027693184,0.00041757396,0.0030398988,0.00046750976,0.0000771474,0.0000017813438,0.0001355219,0.000054964912,0.7760541,0.003978203,0.0013380476,0.21440761],"study_design_scores_gemma":[0.00015910798,0.000006758903,0.0005447919,0.00011790832,0.00004195219,0.0000054715456,0.00039410227,0.00016546174,0.9336418,0.004759124,0.059908237,0.00025531714],"about_ca_topic_score_codex":0.00015856914,"about_ca_topic_score_gemma":0.000013102931,"teacher_disagreement_score":0.21415229,"about_ca_system_score_codex":0.000026306669,"about_ca_system_score_gemma":0.000033857774,"threshold_uncertainty_score":0.9961411},"labels":[],"label_agreement":null},{"id":"W2059005989","doi":"10.1021/cb300729y","title":"<i>De Novo</i> Design of Protein Kinase Inhibitors by <i>in Silico</i> Identification of Hinge Region-Binding Fragments","year":2013,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Biotechnology and Biological Sciences Research Council; Deutscher Akademischer Austauschdienst; Medical Research Council; Bundesministerium für Bildung und Forschung; Wellcome Trust; University of Dundee","keywords":"Kinase; In silico; Drug discovery; Computational biology; Small molecule; Chemical biology; Biochemistry; Biology; Binding site; Enzyme; Protein-Serine-Threonine Kinases; Function (biology); Chemistry; Protein kinase A; Cell biology","score_opus":0.013001538561591202,"score_gpt":0.23527953588983044,"score_spread":0.22227799732823925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059005989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984069,0.00014323271,0.000544603,0.00027687664,0.000013169826,0.00024877093,0.000025853291,0.0000224746,0.00031813988],"genre_scores_gemma":[0.9989158,0.000027871261,0.00044660346,0.000029215573,0.000034847224,0.0003154037,0.00007170552,0.000015154831,0.00014338022],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876046,0.000035139656,0.00058616383,0.0002926705,0.00007903477,0.00024653037],"domain_scores_gemma":[0.9990506,0.00018291028,0.00032436685,0.000324935,0.000059429774,0.00005771481],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016226727,0.00013093598,0.000252337,0.000040886775,0.000023158727,0.000008099983,0.00027637798,0.00025584892,0.00009124245],"category_scores_gemma":[0.00019288725,0.00012615172,0.000053822983,0.00014580984,0.0001679473,0.00005593872,0.00006261349,0.00014818861,0.000020587864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001437915,0.00023581371,0.0017638765,0.00006502963,0.000010916011,3.108804e-7,0.000052418156,0.0000018502084,0.99372226,0.00024670313,0.000605145,0.0032812972],"study_design_scores_gemma":[0.00026727875,0.000011568989,0.00002320464,0.00005537325,0.000008373547,0.0000020286088,0.00004878823,0.00006823636,0.99780345,0.0011497763,0.00044869023,0.00011321794],"about_ca_topic_score_codex":0.00010057813,"about_ca_topic_score_gemma":2.4770873e-7,"teacher_disagreement_score":0.0040812027,"about_ca_system_score_codex":0.000059613736,"about_ca_system_score_gemma":0.000027597442,"threshold_uncertainty_score":0.5144318},"labels":[],"label_agreement":null},{"id":"W2066805549","doi":"10.1039/c4ob02238f","title":"Expanding the scope of fused pyrimidines as kinase inhibitor scaffolds: synthesis and modification of pyrido[3,4-d]pyrimidines","year":2014,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"Cancer Research UK","keywords":"Pyrimidine; Combinatorial chemistry; Scope (computer science); Yield (engineering); Chemistry; Kinase; Stereochemistry; Biochemistry; Computer science; Materials science; Programming language","score_opus":0.009994374785946482,"score_gpt":0.23569278049205264,"score_spread":0.22569840570610616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066805549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99074715,0.0013819123,0.0019165351,0.00045822933,0.000020878837,0.00011335665,0.000031331,0.0000664552,0.0052641258],"genre_scores_gemma":[0.9989793,0.0003261746,0.00020695754,0.000026259153,0.00015068297,0.00006391974,0.000023334625,0.000055833792,0.00016757383],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983666,0.000031031926,0.0005365153,0.00045522003,0.0003106109,0.000300052],"domain_scores_gemma":[0.99814004,0.00023249266,0.0004258657,0.0009254922,0.00015022416,0.0001258837],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003198013,0.00027928135,0.00037912224,0.00003802264,0.00015855533,0.00004068567,0.00044849262,0.00020483643,0.00059437734],"category_scores_gemma":[0.0005760463,0.00022939198,0.00014199002,0.00028885144,0.00033396232,0.00006258321,0.00014443192,0.00008866222,0.000011662407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002224261,0.0001432275,0.00010928298,0.0005777082,0.000054216325,0.0000010520952,0.00008488815,7.074492e-7,0.9958841,0.00014044112,0.000094612034,0.0028875081],"study_design_scores_gemma":[0.00026088048,0.00001002095,0.000064627005,0.00024033272,0.00014508721,0.000018011722,0.00031620375,0.00012603826,0.99766237,0.00020396124,0.0007148915,0.00023757538],"about_ca_topic_score_codex":0.000048685637,"about_ca_topic_score_gemma":0.0000012008285,"teacher_disagreement_score":0.008232088,"about_ca_system_score_codex":0.000040916122,"about_ca_system_score_gemma":0.00008466621,"threshold_uncertainty_score":0.9354334},"labels":[],"label_agreement":null},{"id":"W2068355326","doi":"10.1021/jm030142e","title":"The Combi-Targeting Concept:  Chemical Dissection of the Dual Targeting Properties of a Series of “Combi-Triazenes”","year":2003,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Hospital; Royal Victoria Regional Health Centre","funders":"National Cancer Institute; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Quinazoline; Chemistry; Transfection; Epidermal growth factor receptor; Receptor; Tyrosine kinase; DNA; Cancer research; Biochemistry; Stereochemistry; Biology; Gene","score_opus":0.01098703583652269,"score_gpt":0.2185458560951034,"score_spread":0.20755882025858072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068355326","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99400645,0.0030969065,0.000016531496,0.0005550365,0.00009789276,0.000050867737,0.000007351579,0.0000054479833,0.0021635387],"genre_scores_gemma":[0.9991994,0.00014141687,0.00013767257,0.0000072361076,0.00027481714,0.00000505436,0.0000015843342,0.000016102711,0.00021670814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978254,0.000049286395,0.0011830187,0.00012302134,0.0006192115,0.00020010596],"domain_scores_gemma":[0.9972956,0.00024961552,0.0016513343,0.00026784168,0.00045842142,0.00007714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082666584,0.00016341072,0.00045020695,0.000013322037,0.00014429889,0.000010154825,0.000386006,0.00013083585,0.00014698422],"category_scores_gemma":[0.0017234405,0.00009111324,0.0002599786,0.00015446571,0.00062783656,0.00006662621,0.000055434288,0.00045809062,1.8845286e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013953613,0.00014017045,0.00100102,0.00043705263,0.00008598395,0.0000015558297,0.0005092219,0.000016643358,0.9967936,0.0001467336,0.00042726245,0.00030119342],"study_design_scores_gemma":[0.00056262536,0.000027070613,0.00007269473,0.0006269145,0.00010733193,0.00017974938,0.006365031,0.000018293118,0.9902313,0.00020104079,0.0015209318,0.00008706431],"about_ca_topic_score_codex":0.000009293054,"about_ca_topic_score_gemma":3.6566792e-7,"teacher_disagreement_score":0.0065623736,"about_ca_system_score_codex":0.000048575883,"about_ca_system_score_gemma":0.00022128444,"threshold_uncertainty_score":0.371549},"labels":[],"label_agreement":null},{"id":"W2070746665","doi":"10.1378/chest.125.5_suppl.153s","title":"Activation of the Akt/Nuclear Factor-κB Signaling Axis in Developing Lung Neoplasia","year":2004,"lang":"en","type":"article","venue":"CHEST Journal","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Cancer research; Lung cancer; Lung; Protein kinase B; Signal transduction; Pathology; Internal medicine; Cell biology; Biology","score_opus":0.01881615079430468,"score_gpt":0.24488804687591595,"score_spread":0.22607189608161127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070746665","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99648505,0.00003400895,0.000996242,0.0011340021,0.00003008161,0.00003334627,0.0000022325305,0.000011373261,0.0012736865],"genre_scores_gemma":[0.9978775,0.000022460106,0.0018804658,0.000045811666,0.00012605025,0.0000028223799,8.22109e-7,0.000015878266,0.000028184179],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99926126,0.000011306962,0.00030076914,0.00010246978,0.00016752623,0.00015668327],"domain_scores_gemma":[0.99948394,0.00005334866,0.00022253692,0.000147617,0.000052096882,0.000040466966],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000108546286,0.00009099082,0.000120328084,0.00003950772,0.00017179063,0.00003908499,0.00023063306,0.00007670906,0.00021823117],"category_scores_gemma":[0.00007784926,0.00006973505,0.00007650197,0.00015459071,0.000035404984,0.000110928355,0.00003567078,0.00031002137,0.000005594438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010074841,0.00006559182,0.007425229,0.00009512838,0.000026628974,0.000001968267,0.001449882,0.0009558937,0.9854383,0.0013466359,0.000028827228,0.0031558461],"study_design_scores_gemma":[0.00034834156,0.0000030524593,0.022421699,0.0004117259,0.0000098693035,0.000036534195,0.00048832956,0.00006781576,0.9728246,0.001063737,0.0022117815,0.00011254995],"about_ca_topic_score_codex":0.00002006053,"about_ca_topic_score_gemma":0.000004749558,"teacher_disagreement_score":0.01499647,"about_ca_system_score_codex":0.0002292765,"about_ca_system_score_gemma":0.00015525645,"threshold_uncertainty_score":0.2843713},"labels":[],"label_agreement":null},{"id":"W2072226383","doi":"10.1007/s10600-012-0397-8","title":"Quinazoline Alkaloids from Streptomyces michiganensis","year":2012,"lang":"en","type":"article","venue":"Chemistry of Natural Compounds","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lakehead University","funders":"","keywords":"Quinazoline; Chemistry; Streptomyces; Strain (injury); Stereochemistry; Bacteria; Biology; Genetics","score_opus":0.010433049682985121,"score_gpt":0.2365003972487238,"score_spread":0.22606734756573868,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072226383","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9690056,0.003311408,0.000005567085,0.00022647987,0.000096385374,0.000030220233,0.00016150613,0.00011054581,0.027052326],"genre_scores_gemma":[0.9956633,0.00005047864,0.0010105236,0.000035400128,0.00090010744,0.000014364321,0.00043031498,0.000029494558,0.0018660475],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986067,0.000007429066,0.0004107479,0.00029784977,0.0002795301,0.0003977459],"domain_scores_gemma":[0.99866676,0.00020979183,0.00023987098,0.0006069698,0.00009972,0.00017686283],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007711219,0.00026449832,0.0003657698,0.000018098133,0.00010691557,0.000024244448,0.0004161302,0.00018390872,0.0021382933],"category_scores_gemma":[0.00006109397,0.00024907792,0.00019443025,0.00012915392,0.00017433974,0.00013397208,0.00011969027,0.0003209573,0.000039950126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023530522,0.00020554123,0.0055148983,0.00010069924,0.00007401333,7.4893916e-7,0.00010282297,9.211479e-7,0.9907681,0.000053754,0.0016384685,0.001516556],"study_design_scores_gemma":[0.00031253076,0.000002546649,0.0019518059,0.000057979465,0.00006429715,0.000013263992,0.00025487193,0.00007441057,0.96890146,0.00018875525,0.0278957,0.0002824094],"about_ca_topic_score_codex":0.00009805033,"about_ca_topic_score_gemma":0.000002349962,"teacher_disagreement_score":0.026657708,"about_ca_system_score_codex":0.0000535657,"about_ca_system_score_gemma":0.000031550026,"threshold_uncertainty_score":0.9999961},"labels":[],"label_agreement":null},{"id":"W2084524589","doi":"10.5539/gjhs.v4n1p162","title":"Uses of 2-Ethoxy-4(3H) quinazolinone in Synthesis of Quinazoline and Quinazolinone Derivatives of Antimicrobial Activity: The Solvent Effect","year":2011,"lang":"en","type":"article","venue":"Global Journal of Health Science","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Quinazolinone; Chemistry; Chalcone; Alkyl; Organic chemistry; Ethyl chloroformate; Quinazoline; Moiety; Solvent; Medicinal chemistry","score_opus":0.03032833569506766,"score_gpt":0.3142757557435275,"score_spread":0.28394742004845985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084524589","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99762106,0.0007393667,0.00029716236,0.00048238412,0.000073055315,0.00017476492,0.00006391506,0.0000059527706,0.0005423552],"genre_scores_gemma":[0.997153,0.0007185394,0.0020420935,0.000026507314,0.000041008352,0.000006401638,3.0207235e-7,0.000009814364,0.0000023548603],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970204,0.000143637,0.0014063487,0.00030046722,0.00064694585,0.00048216738],"domain_scores_gemma":[0.9961772,0.00044957869,0.002366267,0.00044843557,0.0003878369,0.00017067145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0030996823,0.00023112664,0.0009935733,0.00019429107,0.0001666804,0.000014586588,0.00087095285,0.00008951275,0.000039752453],"category_scores_gemma":[0.0005532813,0.00016126421,0.00016646381,0.000887249,0.0016866652,0.00029004586,0.00021248234,0.00025171827,6.921472e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00067384506,0.001402252,0.11755666,0.0011674407,0.00006392626,0.0000076292126,0.0009636277,0.00004949714,0.83402973,0.0013970532,0.000039255294,0.042649098],"study_design_scores_gemma":[0.0005442931,0.000276324,0.18053716,0.0008048777,0.00004548662,0.00015859416,0.00038021617,0.00005388981,0.8167607,0.00029355456,0.000020355676,0.0001244972],"about_ca_topic_score_codex":0.00095775374,"about_ca_topic_score_gemma":0.00006076262,"teacher_disagreement_score":0.06298051,"about_ca_system_score_codex":0.00014366805,"about_ca_system_score_gemma":0.00085008325,"threshold_uncertainty_score":0.6576163},"labels":[],"label_agreement":null},{"id":"W2091796767","doi":"10.1021/ol902924x","title":"Tandem Palladium-Catalyzed Addition/Cyclocarbonylation: An Efficient Synthesis of 2-Heteroquinazolin-4(<i>3H</i>)-ones","year":2010,"lang":"en","type":"article","venue":"Organic Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Palladium; Catalysis; Tandem; Combinatorial chemistry; Reaction conditions; Organic chemistry","score_opus":0.00682955659580963,"score_gpt":0.20982751080795695,"score_spread":0.2029979542121473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091796767","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957128,0.000018603696,0.00052474195,0.0017926324,0.00014240132,0.00011034728,0.00010563376,0.00016228735,0.0014305298],"genre_scores_gemma":[0.9980858,0.000008386768,0.0009770463,0.00019661103,0.00046178175,0.00008801329,0.00009609867,0.00006479718,0.000021477865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982892,0.000026676962,0.0005009212,0.00048412525,0.0003477184,0.00035133297],"domain_scores_gemma":[0.9982332,0.00025082365,0.00029007232,0.00097228657,0.0000803435,0.00017327434],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00019010992,0.0002704158,0.0003424554,0.00008420507,0.0001881013,0.00004972585,0.00047026502,0.00018053128,0.00567336],"category_scores_gemma":[0.00013397605,0.00026505202,0.00014875668,0.00023157902,0.00019949285,0.00010234384,0.00006521835,0.00028638696,0.00014359743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000110159235,0.00022203766,0.00076354784,0.000037296995,0.000042504165,0.000003302166,0.00013419881,0.000036535148,0.9961615,0.00043471492,0.00032502582,0.0018283296],"study_design_scores_gemma":[0.0003231375,0.0000057426323,0.0024184939,0.00003739804,0.00009571879,0.000022018592,0.00008756659,0.00054435065,0.99471277,0.00006931549,0.0013480562,0.0003354168],"about_ca_topic_score_codex":0.000031025225,"about_ca_topic_score_gemma":0.00003972684,"teacher_disagreement_score":0.0055297627,"about_ca_system_score_codex":0.000052649088,"about_ca_system_score_gemma":0.00006139416,"threshold_uncertainty_score":0.99998015},"labels":[],"label_agreement":null},{"id":"W2095003522","doi":"10.1016/j.bmcl.2004.12.015","title":"Synthesis of half-mustard combi-molecules with fluorescence properties: correlation with EGFR status","year":2005,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Victoria Hospital; McGill University","funders":"National Cancer Institute","keywords":"Chemistry; Fluorescence; Flow cytometry; Tyrosine kinase; DNA; Cell culture; Biophysics; Biochemistry; Molecular biology; Signal transduction; Genetics; Biology","score_opus":0.007645262843477032,"score_gpt":0.18902605904125616,"score_spread":0.18138079619777914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095003522","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905818,0.00025388176,0.0008293693,0.0051197703,0.000011809611,0.00013254514,0.000027361879,0.0001136001,0.0029298305],"genre_scores_gemma":[0.99733967,0.000041417003,0.00186831,0.00019909932,0.00023182774,0.00006943133,0.000033635835,0.000056523873,0.00016007823],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99803907,0.000014905791,0.0004212912,0.00047808985,0.00059169065,0.00045497267],"domain_scores_gemma":[0.9986442,0.000112102294,0.00031670372,0.000597836,0.00012013708,0.00020904445],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00010382181,0.00033305204,0.00038110296,0.00003143971,0.00012362396,0.000024520366,0.00034437838,0.00012572994,0.00092382997],"category_scores_gemma":[0.00009616611,0.00024228016,0.00006109637,0.00022378158,0.0004912976,0.00010044544,0.000039771257,0.00028874798,0.00002392502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018606463,0.00016178537,0.0020137234,0.0003884021,0.00009334735,0.00001287711,0.0002638137,0.00005736575,0.9934417,0.000013748002,0.0004791914,0.002887994],"study_design_scores_gemma":[0.0006145345,0.00002336593,0.0004966077,0.00067416695,0.00019169324,0.00007711641,0.00085348164,0.00035605015,0.99349165,0.0000012450214,0.0028871892,0.0003328995],"about_ca_topic_score_codex":0.00009437039,"about_ca_topic_score_gemma":0.00001003945,"teacher_disagreement_score":0.006757845,"about_ca_system_score_codex":0.00019844124,"about_ca_system_score_gemma":0.00018631226,"threshold_uncertainty_score":0.99998945},"labels":[],"label_agreement":null},{"id":"W2095482501","doi":"10.3797/scipharm.1206-04","title":"Synthesis of New N,N'-Bis(5-arylidene-4-oxo-4,5-dihydrothiazolin-2-yl)piperazine Derivatives Under Microwave Irradiation and Preliminary Biological Evaluation","year":2012,"lang":"en","type":"article","venue":"Scientia Pharmaceutica","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Cancéropôle Grand Ouest; Institut National Du Cancer; Agence Universitaire de la Francophonie","keywords":"Piperazine; DYRK1A; Microwave irradiation; Chemistry; Rhodanine; IC50; Kinase; Microwave; Combinatorial chemistry; In vitro; Biochemistry; Organic chemistry; Computer science","score_opus":0.08551126844752122,"score_gpt":0.3533457910046944,"score_spread":0.26783452255717316,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095482501","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98672146,0.0034572552,0.00068330555,0.0011904708,0.00012838225,0.00033230288,0.00004166467,0.00007101044,0.0073741814],"genre_scores_gemma":[0.9967507,0.00032638817,0.002022912,0.00012777586,0.0002670966,0.00011084309,0.00003214164,0.000024640949,0.0003375078],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980885,0.00009834233,0.0004532528,0.00045092424,0.00044079073,0.00046820403],"domain_scores_gemma":[0.99854326,0.00037012692,0.00024934413,0.0003721325,0.00013650634,0.00032861877],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009192496,0.0002431407,0.00028366403,0.00012576152,0.00022972295,0.000049295766,0.00025878754,0.00015994335,0.0029854828],"category_scores_gemma":[0.00028278996,0.0002166438,0.00010381332,0.00032029994,0.00032261424,0.00031046785,0.00014244019,0.00017233122,0.00007088928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006270636,0.00029344132,0.0041190316,0.00006248659,0.00007190714,2.3040135e-7,0.00046104082,0.000045459332,0.9526812,0.0012338888,0.00095443596,0.040014196],"study_design_scores_gemma":[0.0005677381,0.000020491823,0.029935146,0.000060445524,0.00028435639,0.000017608727,0.000308415,0.00306844,0.9563775,0.00068530266,0.008379815,0.00029475222],"about_ca_topic_score_codex":0.000016503465,"about_ca_topic_score_gemma":0.0000016624476,"teacher_disagreement_score":0.039719444,"about_ca_system_score_codex":0.00007726073,"about_ca_system_score_gemma":0.00015103605,"threshold_uncertainty_score":0.99792594},"labels":[],"label_agreement":null},{"id":"W2097698114","doi":"10.1124/jpet.104.071977","title":"The Combi-Targeting Concept: Dissection of the Binary Mechanism of Action of the Combi-Triazene SMA41 in Vitro and Antitumor Activity in Vivo","year":2004,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Victoria Hospital","funders":"","keywords":"Autophosphorylation; In vivo; A431 cells; Quinazoline; Epidermal growth factor receptor; Molecular biology; Chemistry; In vitro; Mechanism of action; Tyrosine kinase; Cancer research; Kinase; Biology; Biochemistry; Cell cycle; Signal transduction; Receptor; Protein kinase A; Stereochemistry; Cell","score_opus":0.021419159270471007,"score_gpt":0.321222353934921,"score_spread":0.29980319466445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097698114","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99777126,0.0012324371,0.0000125116785,0.0006187016,0.0001976354,0.00010504919,0.000007719948,0.0000015655552,0.000053145475],"genre_scores_gemma":[0.9993542,0.0005159094,0.000027806538,0.000044220287,0.00003672184,0.0000054148277,1.8385141e-7,0.000006608699,0.0000089350915],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992417,0.0001028253,0.00036482568,0.00007499943,0.00011402645,0.00010161712],"domain_scores_gemma":[0.9991748,0.00014672954,0.0005496148,0.000077144534,0.00003465317,0.000017060967],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002699389,0.00008823306,0.00020900254,0.000029830351,0.00012702141,0.0000050210156,0.00015336237,0.00007038914,0.000021332697],"category_scores_gemma":[0.0000057009192,0.000051809046,0.000072860625,0.00010468115,0.0002814863,0.00006541412,0.00006084605,0.00025856233,3.0299987e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000497633,0.00051605667,0.0006274247,0.00002056655,0.000057576814,7.0705056e-7,0.00085812993,0.00006774741,0.99655783,0.00036275722,0.000004740242,0.00042883708],"study_design_scores_gemma":[0.0016665966,0.00007712827,0.0016257118,0.00003802601,0.00004653388,0.000024636971,0.002006768,0.00021741362,0.9936334,0.00055798335,0.000059358248,0.00004646652],"about_ca_topic_score_codex":0.000029176761,"about_ca_topic_score_gemma":0.000005025912,"teacher_disagreement_score":0.0029244465,"about_ca_system_score_codex":0.000061754195,"about_ca_system_score_gemma":0.000049847982,"threshold_uncertainty_score":0.21127117},"labels":[],"label_agreement":null},{"id":"W2117282934","doi":"10.1002/0471264180.os078.26","title":"Methyl Carbamate Formation Via Modified <scp>H</scp> ofmann Rearrangement Reactions: Methyl N‐(p‐Methoxyphenyl)Carbamate","year":2003,"lang":"en","type":"other","venue":"Organic Syntheses","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Carbamate; Chemistry; Benzamide; Ethyl carbamate; Medicinal chemistry; Stereochemistry; Organic chemistry","score_opus":0.024692395831643368,"score_gpt":0.2531208629074794,"score_spread":0.22842846707583606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117282934","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011907388,0.0039549572,0.008799322,0.00022078877,0.0005487983,0.00075065746,0.00045566747,0.0013168284,0.9827622],"genre_scores_gemma":[0.032413688,0.00524117,0.0077509726,0.00019340473,0.0011637114,0.0012352492,0.00037960755,0.0021061073,0.9495161],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9958026,0.00026468255,0.001104863,0.0011258879,0.0007889622,0.00091305096],"domain_scores_gemma":[0.9949737,0.0012543771,0.0012597126,0.00206667,0.00015124581,0.00029430518],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0007755519,0.0010165583,0.0011705342,0.000468792,0.00032200798,0.00019295378,0.00083756127,0.0010072299,0.014675108],"category_scores_gemma":[0.0015560037,0.0009842265,0.0004149521,0.00055290473,0.00016480689,0.00020646029,0.0001690944,0.0006350682,0.0018108619],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009025346,0.0004545394,0.000010988972,0.0014567306,0.0009970197,0.000014486406,0.00054843153,0.000011048774,0.7128006,0.0017671684,0.26746514,0.014464776],"study_design_scores_gemma":[0.00022671804,0.0000126390205,0.0000044291223,0.00064235006,0.0004898341,0.000036200003,0.0007318409,0.0001206442,0.27101362,0.0006972653,0.725626,0.00039848528],"about_ca_topic_score_codex":0.0004596538,"about_ca_topic_score_gemma":0.00011299763,"teacher_disagreement_score":0.45816082,"about_ca_system_score_codex":0.0003497077,"about_ca_system_score_gemma":0.00013309582,"threshold_uncertainty_score":0.99926084},"labels":[],"label_agreement":null},{"id":"W2121559221","doi":"","title":"Lysosomal Oxidative Stress Cytotoxicity Induced by Dacarbazine and It’s Pyridine Derivative in Hepatocytes","year":2006,"lang":"en","type":"article","venue":"Iranian journal of pharmaceutical sciences","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Cytotoxicity; Chemistry; Dacarbazine; Stereochemistry; Biochemistry; Cancer research; Melanoma; Biology; In vitro","score_opus":0.04325017242070123,"score_gpt":0.33155437928432346,"score_spread":0.28830420686362224,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121559221","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99311596,0.0004170851,0.00005314171,0.0025764487,0.000021321139,0.000060663395,0.000039294235,0.000008803637,0.0037072818],"genre_scores_gemma":[0.99926883,0.00006997298,0.00034452518,0.00012256489,0.00015379442,0.000005162206,0.0000011994148,0.0000069304865,0.000027037324],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985102,0.000056704877,0.0004980781,0.00023386221,0.00039266938,0.0003084803],"domain_scores_gemma":[0.9991237,0.000300139,0.000253017,0.00007089072,0.00007906083,0.00017321043],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046762018,0.00015746045,0.0002726302,0.00006499682,0.00015928212,0.000077726094,0.00034209597,0.00006782661,0.00040706416],"category_scores_gemma":[0.00009922729,0.00012083281,0.00005794976,0.0003211764,0.00048085552,0.0002224119,0.000056095538,0.00032245004,0.000003261567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041759817,0.00025314902,0.053581145,0.000019309386,0.000014231103,0.000015183843,0.00012138628,0.000032179636,0.9431074,0.00066179736,0.00015018952,0.0020022602],"study_design_scores_gemma":[0.00077925116,0.00007158199,0.0093307,0.00010685326,0.000024297913,0.00003640491,0.0003689942,0.0021096978,0.9851209,0.0008261266,0.0010519034,0.00017332075],"about_ca_topic_score_codex":0.00006892159,"about_ca_topic_score_gemma":0.000031562984,"teacher_disagreement_score":0.044250447,"about_ca_system_score_codex":0.00004933298,"about_ca_system_score_gemma":0.00007418153,"threshold_uncertainty_score":0.4927419},"labels":[],"label_agreement":null},{"id":"W2133355522","doi":"10.1111/j.1747-0285.2009.00786.x","title":"Rational Design of Multitargeted Tyrosine Kinase Inhibitors: A Novel Approach","year":2009,"lang":"en","type":"article","venue":"Chemical Biology & Drug Design","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Regional Health Centre; Royal Victoria Hospital","funders":"Canadian Institutes of Health Research; Ministry of Education, India; Ministry of Earth Sciences","keywords":"Epidermal growth factor receptor; Tyrosine kinase; Proto-oncogene tyrosine-protein kinase Src; Quinazoline; Growth factor receptor; Epidermal growth factor; Cancer research; Chemistry; Receptor tyrosine kinase; Platelet-derived growth factor receptor; Cell biology; Growth factor receptor inhibitor; Biochemistry; Kinase; Biology; Receptor; Pharmacology; Stereochemistry; Growth factor","score_opus":0.0289405585529809,"score_gpt":0.2526529038299845,"score_spread":0.22371234527700362,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133355522","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.22810557,0.0014060378,0.76383424,0.0013652567,0.000065654596,0.00070011284,0.00018486546,0.000329482,0.0040087635],"genre_scores_gemma":[0.8894439,0.00001809006,0.10975213,0.00011810365,0.00021474659,0.00009187353,0.00020297292,0.00001650471,0.0001417127],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985397,0.000048780075,0.0004831545,0.00048162797,0.00012942252,0.00031730474],"domain_scores_gemma":[0.9985853,0.00060887204,0.0001832781,0.0003766848,0.00012894356,0.00011692607],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003422634,0.00024067503,0.0003536977,0.00004995993,0.00008524773,0.000011347699,0.00033698409,0.00031507286,0.00020081711],"category_scores_gemma":[0.00030560055,0.00021237496,0.00012150452,0.00017921171,0.0002438453,0.00004994694,0.00003763789,0.0002879636,0.000024252737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000087040105,0.0008124564,0.0000319448,0.000018885183,0.000028159237,4.9238264e-7,0.000068799025,0.00017251032,0.9929161,0.002202894,0.0018742741,0.0017864532],"study_design_scores_gemma":[0.0006293187,0.000022643135,0.000023505067,0.000024055604,0.00003362657,0.0000063018074,0.000036051762,0.0050992924,0.9915535,0.0018491773,0.0004939158,0.00022861364],"about_ca_topic_score_codex":0.0000065467857,"about_ca_topic_score_gemma":5.0464795e-8,"teacher_disagreement_score":0.66133827,"about_ca_system_score_codex":0.000049268274,"about_ca_system_score_gemma":0.000091940565,"threshold_uncertainty_score":0.86604},"labels":[],"label_agreement":null},{"id":"W2136967060","doi":"10.2174/1389557053544056","title":"Medicinal Chemistry and Properties of 1,2,4-Thiadiazoles","year":2005,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Apotex (Canada)","funders":"","keywords":"Cysteine; Pharmacophore; Thiadiazoles; Chemistry; Moiety; Thiol; Cysteine Proteinase Inhibitors; Stereochemistry; Cystamine; Electrophile; Enzyme; Covalent bond; Cathepsin; Combinatorial chemistry; Biochemistry; Medicinal chemistry; Organic chemistry","score_opus":0.06516099362023502,"score_gpt":0.32777115580110083,"score_spread":0.2626101621808658,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136967060","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00076737994,0.9819689,0.0000024715705,0.00012808276,0.000040325172,0.0004218953,0.000085215215,0.000048738093,0.01653699],"genre_scores_gemma":[0.00045288663,0.9941652,0.0002767205,0.00004215741,0.001402745,0.0007277549,0.00014218887,0.00010480854,0.002685579],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9947283,0.00007067116,0.00279962,0.0010903142,0.00064595917,0.0006651143],"domain_scores_gemma":[0.996621,0.00026046808,0.0014210205,0.0012653468,0.00006831543,0.00036381438],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010302096,0.0010962711,0.004413333,0.00006155342,0.00009298863,0.00002663642,0.0010589662,0.0009922499,0.0030962205],"category_scores_gemma":[0.0006988328,0.0008289473,0.0005949498,0.0003790692,0.00083188515,0.00007020553,0.000247235,0.001479469,0.00004381388],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008369644,0.00015953065,0.000009278831,0.12532541,0.00007455561,0.000016420778,0.000109183646,5.739149e-8,0.008203765,0.0000031949196,0.0007954893,0.86529475],"study_design_scores_gemma":[0.00032904875,0.0000067679684,0.0000010064624,0.08692281,0.0009058256,0.00031709016,0.00020259168,0.0000072884736,0.012088316,0.000008368875,0.8985578,0.0006531038],"about_ca_topic_score_codex":0.000028122557,"about_ca_topic_score_gemma":0.000004757291,"teacher_disagreement_score":0.8977623,"about_ca_system_score_codex":0.00023058064,"about_ca_system_score_gemma":0.000509943,"threshold_uncertainty_score":0.9994161},"labels":[],"label_agreement":null},{"id":"W2144360055","doi":"10.1016/j.bmcl.2004.06.063","title":"Synthesis and structural–activity relationships of 3-hydroxyquinazoline-2,4-dione antibacterial agents","year":2004,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":75,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"NAEJA-RGM Pharmaceuticals (Canada)","funders":"","keywords":"DNA gyrase; Chemistry; Antibacterial activity; Antibacterial agent; Gram; Stereochemistry; In vitro; Potency; Structure–activity relationship; Antibiotics; Chemical synthesis; Combinatorial chemistry; Escherichia coli; Bacteria; Biochemistry; Biology; Genetics","score_opus":0.01873872148372895,"score_gpt":0.23567547288065985,"score_spread":0.2169367513969309,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144360055","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953325,0.000090892,0.00014271817,0.003378886,0.000053180607,0.00007663767,0.00007923342,0.00007760407,0.0007683422],"genre_scores_gemma":[0.9989649,0.00005703602,0.0002969293,0.000069655915,0.00048170492,0.000019064672,0.000032614076,0.000037414706,0.000040659117],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99840504,0.00002044787,0.00042749435,0.00046473724,0.0003604398,0.00032181334],"domain_scores_gemma":[0.9987675,0.00017671175,0.00031170787,0.0004977024,0.000048505175,0.00019785501],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018079705,0.00029196165,0.0004008223,0.00003576261,0.00020531335,0.000023207005,0.00027336902,0.00019974491,0.001072241],"category_scores_gemma":[0.0003217192,0.00027752304,0.0000938038,0.00017710568,0.0003383956,0.000106064785,0.00008296329,0.000344875,0.000011508829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045259298,0.000066295084,0.00204483,0.00023609525,0.00006326485,0.00001024072,0.0001184297,0.00000607573,0.99644166,0.000035017198,0.00008552893,0.00084729533],"study_design_scores_gemma":[0.00068345875,0.0000055732844,0.015109948,0.0002018599,0.0001378792,0.00008441272,0.0001200022,0.000023641162,0.9830242,0.00008319939,0.00025976473,0.00026607353],"about_ca_topic_score_codex":0.00009645693,"about_ca_topic_score_gemma":0.0000024709386,"teacher_disagreement_score":0.0134174805,"about_ca_system_score_codex":0.00013487758,"about_ca_system_score_gemma":0.00007948475,"threshold_uncertainty_score":0.9999677},"labels":[],"label_agreement":null},{"id":"W2145184104","doi":"10.1002/ardp.201200267","title":"Novel Dithiocarbamic Acid Esters Derived from 6‐Aminomethyl‐4‐anilinoquinazolines and 6‐Aminomethyl‐4‐anilino‐3‐cyanoquinolines as Potent EGFR Inhibitors","year":2012,"lang":"en","type":"article","venue":"Archiv der Pharmazie","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Emergent BioSolutions (Canada)","funders":"","keywords":"Chemistry; Lapatinib; Kinase; ErbB; Stereochemistry; Positive control; Cell culture; MTT assay; Biochemistry; Combinatorial chemistry; In vitro; Receptor; Cancer","score_opus":0.022588038950587558,"score_gpt":0.26541412167964157,"score_spread":0.242826082729054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145184104","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98673064,0.004940892,0.001267896,0.00096007384,0.0005048425,0.00034830667,0.00043687658,0.00034157024,0.004468933],"genre_scores_gemma":[0.9895621,0.0007423284,0.0055778073,0.00067022676,0.0022848588,0.00022571621,0.00034972627,0.00016427458,0.00042295514],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99596673,0.00008166011,0.0009907681,0.0010674899,0.0006053294,0.0012880147],"domain_scores_gemma":[0.997013,0.00062728074,0.00040134075,0.0010156167,0.00011660701,0.0008261714],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003215023,0.0008291211,0.0007559368,0.0002512261,0.00046030633,0.00015452853,0.00071146333,0.00027587826,0.0005202213],"category_scores_gemma":[0.00019006722,0.00079527905,0.0003316945,0.00031364828,0.00048638135,0.00056213036,0.0005524832,0.00067271607,0.00032307403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010555216,0.0007621169,0.016145585,0.000121486875,0.00029466575,0.000008343428,0.0015889048,0.000012630421,0.9517073,0.00038680885,0.00025353476,0.028613063],"study_design_scores_gemma":[0.0019203487,0.000037637434,0.04481072,0.0001147812,0.00045023137,0.00011000248,0.0008943366,0.000482493,0.94196254,0.0009163881,0.007173322,0.001127207],"about_ca_topic_score_codex":0.00033531841,"about_ca_topic_score_gemma":0.000024370383,"teacher_disagreement_score":0.028665135,"about_ca_system_score_codex":0.00012156816,"about_ca_system_score_gemma":0.00011877591,"threshold_uncertainty_score":0.9994498},"labels":[],"label_agreement":null},{"id":"W2151106348","doi":"10.1016/s0040-4039(02)01714-8","title":"An efficient protocol for the formation of aminothiatriazoles from thiocarbamoylimidazolium salts","year":2002,"lang":"en","type":"article","venue":"Tetrahedron Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Ontario","keywords":"Chemistry; Azide; Combinatorial chemistry; Methylation; Salt (chemistry); Ion; Organic chemistry; Medicinal chemistry; DNA","score_opus":0.03190029353941471,"score_gpt":0.2748399556999934,"score_spread":0.24293966216057872,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151106348","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9240885,0.00005157542,0.018195916,0.006523727,0.00008641794,0.048019152,0.00026654796,0.00025519228,0.0025129933],"genre_scores_gemma":[0.9222134,0.0000017245779,0.00091083575,0.0003367414,0.0003031149,0.07616285,0.000022098528,0.000025593881,0.000023659815],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989281,0.000016394588,0.0003726271,0.00022551735,0.0002262249,0.000231132],"domain_scores_gemma":[0.9987888,0.00030959203,0.0002310933,0.00058105204,0.000038243274,0.000051236562],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012498912,0.00015463549,0.00016127003,0.000035712757,0.00016640413,0.000038688355,0.00037575237,0.000074996664,0.0005189847],"category_scores_gemma":[0.000024743607,0.0001125105,0.00012563204,0.0000816112,0.00008735961,0.00008877158,0.000018947365,0.00011089215,0.000026526266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009285245,0.0005796297,0.00033060086,0.00027036757,0.00004692851,5.4485037e-7,0.0016727531,0.00395742,0.9620553,0.00081185205,0.008360399,0.021821307],"study_design_scores_gemma":[0.0017573421,0.000041836436,0.0015909919,0.0000777241,0.00008961328,0.0000023258037,0.00048696974,0.16824357,0.80402935,0.00010069148,0.02324775,0.0003318387],"about_ca_topic_score_codex":0.000059785958,"about_ca_topic_score_gemma":0.000007832885,"teacher_disagreement_score":0.16428615,"about_ca_system_score_codex":0.00004797541,"about_ca_system_score_gemma":0.000007339194,"threshold_uncertainty_score":0.56825185},"labels":[],"label_agreement":null},{"id":"W2166163013","doi":"10.18433/j3501w","title":"Transport Characteristics of Tryptanthrin and its Inhibitory Effect on P-gp and MRP2 in Caco-2 Cells","year":2011,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Northwest University","keywords":"Caco-2; Multidrug resistance-associated protein 2; Chemistry; Inhibitory postsynaptic potential; Pharmacology; Traditional medicine; Biochemistry; Transporter; In vitro; Biology; Medicine; ATP-binding cassette transporter; Endocrinology; Gene","score_opus":0.062310120226216716,"score_gpt":0.34655628254633214,"score_spread":0.2842461623201154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2166163013","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962719,0.0008597659,0.000004394453,0.00015540967,0.00009296791,0.00007634864,0.000019119814,0.0000060832044,0.0025139754],"genre_scores_gemma":[0.99814725,0.0015338615,0.00009198679,0.000073048745,0.00012374237,0.000004338449,2.412066e-7,0.000008035762,0.000017490202],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985853,0.000050355837,0.00057753467,0.00020350775,0.0003407449,0.00024259507],"domain_scores_gemma":[0.9991214,0.00025400886,0.00027754816,0.000061514904,0.000050896197,0.00023460157],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082082604,0.00015511579,0.00033592884,0.00011239395,0.000081610815,0.000014552363,0.00023325565,0.000043127573,0.0005839499],"category_scores_gemma":[0.000036066336,0.000115700735,0.00007255541,0.00017368961,0.0003782433,0.00018802837,0.000029094228,0.00034065562,0.0000031736013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033099434,0.00031087344,0.026268559,0.00015779294,0.000017343615,0.000036967227,0.00035118323,0.0000014504673,0.9233435,0.00021627704,0.000014549799,0.0489505],"study_design_scores_gemma":[0.0010929186,0.00014650941,0.011993983,0.00013024584,0.00007456992,0.00004224298,0.00006803073,0.0005864415,0.9817476,0.00003848426,0.003949935,0.00012900292],"about_ca_topic_score_codex":0.000010897202,"about_ca_topic_score_gemma":0.0000012336639,"teacher_disagreement_score":0.058404125,"about_ca_system_score_codex":0.000020571119,"about_ca_system_score_gemma":0.000063511085,"threshold_uncertainty_score":0.6393842},"labels":[],"label_agreement":null},{"id":"W2179437944","doi":"10.1111/cbdd.12692","title":"Novel Quinazoline Derivatives Bearing Various 4‐Aniline Moieties as Potent <scp>EGFR</scp> Inhibitors with Enhanced Activity Against <scp>NSCLC</scp> Cell Lines","year":2015,"lang":"en","type":"letter","venue":"Chemical Biology & Drug Design","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SKiN Health; University of British Columbia","funders":"Natural Science Foundation of Liaoning Province; National Natural Science Foundation of China","keywords":"Gefitinib; Quinazoline; EGFR inhibitors; Epidermal growth factor receptor; IC50; Chemistry; Pharmacology; In vitro; Biochemistry; Receptor; Biology; Stereochemistry","score_opus":0.020222908764718474,"score_gpt":0.23720422221067067,"score_spread":0.2169813134459522,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2179437944","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9491703,0.0015599083,0.0146218445,0.016358854,0.00033756837,0.0011600159,0.0005545141,0.00090048,0.0153365405],"genre_scores_gemma":[0.92423886,0.00054626603,0.014222872,0.030234408,0.010327999,0.0014885466,0.003670192,0.0006687541,0.014602127],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99407667,0.00018342273,0.0011230701,0.0022567336,0.0006454637,0.0017146439],"domain_scores_gemma":[0.9926755,0.0035383159,0.0011933714,0.0014940817,0.0006544693,0.00044428388],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.00052508817,0.0016694361,0.0019003314,0.00022491104,0.0003366026,0.00014549929,0.0014525666,0.0029379805,0.00003616329],"category_scores_gemma":[0.0013298161,0.0014158759,0.0004639092,0.00046168332,0.001182425,0.00017635834,0.0005848847,0.0038533157,0.00017647812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003211461,0.0005792712,0.000028257218,0.00030102063,0.00029245776,0.00003575335,0.00053920184,0.00007409349,0.8575735,0.0000121890425,0.1394143,0.0011178653],"study_design_scores_gemma":[0.0011308712,0.00008993938,0.0000062732984,0.0002759383,0.0002666252,0.00003790858,0.00037583458,0.00014963649,0.8905119,0.00041732902,0.106320016,0.00041774014],"about_ca_topic_score_codex":0.00012519366,"about_ca_topic_score_gemma":0.0000051445077,"teacher_disagreement_score":0.03309428,"about_ca_system_score_codex":0.0004687446,"about_ca_system_score_gemma":0.00073055143,"threshold_uncertainty_score":0.99960524},"labels":[],"label_agreement":null},{"id":"W221131143","doi":"10.1107/s1600536814006746","title":"<i>N</i>-Benzyl-2-chloroquinazolin-4-amine","year":2014,"lang":"en","type":"article","venue":"Acta Crystallographica Section E Structure Reports Online","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Amine gas treating; Chemistry; Organic chemistry","score_opus":0.006069411329299791,"score_gpt":0.22425007834593622,"score_spread":0.21818066701663644,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W221131143","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9884292,0.00009281673,0.00073048874,0.0013178014,0.00048534985,0.00017493051,0.00015601687,0.00060193695,0.008011456],"genre_scores_gemma":[0.9946926,0.0000963429,0.0014665205,0.00027191266,0.0019340458,0.00004144705,0.0008106952,0.00009330895,0.0005931038],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99700433,0.000038735467,0.0009396918,0.00094471517,0.0005195604,0.00055295724],"domain_scores_gemma":[0.9972805,0.00013264701,0.0006840495,0.001367074,0.00025129505,0.0002844532],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022457552,0.00048473716,0.0005223306,0.000261034,0.00038701468,0.00009227105,0.00028824568,0.0004605958,0.0020545244],"category_scores_gemma":[0.00023138692,0.000443564,0.00032753512,0.0006359146,0.00020564391,0.00020036974,0.000102624545,0.0006332079,1.620313e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024003099,0.00022581151,0.004803254,0.00008062094,0.00009458527,0.00002477416,0.00003071035,0.000060442413,0.98808897,0.00008113671,0.00090177666,0.0055839354],"study_design_scores_gemma":[0.00037080032,0.000056490582,0.013295877,0.00004718705,0.00013231505,0.0011368184,0.00007381074,0.00038723834,0.003269311,0.005060832,0.97555417,0.0006151433],"about_ca_topic_score_codex":0.00012401416,"about_ca_topic_score_gemma":0.00042516357,"teacher_disagreement_score":0.98481965,"about_ca_system_score_codex":0.000056847737,"about_ca_system_score_gemma":0.00005747943,"threshold_uncertainty_score":0.99980164},"labels":[],"label_agreement":null},{"id":"W2245414184","doi":"10.1200/jco.2009.27.15_suppl.10579","title":"Early results of a PMH Phase II Consortium trial of AZD0530 in advanced soft tissue sarcoma (STS)","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Internal medicine; Sarcoma; Adverse effect; Oncology; Clinical endpoint; Soft tissue sarcoma; Phases of clinical research; Rhabdomyosarcoma; Surgery; Chemotherapy; Clinical trial; Pathology","score_opus":0.08092407875851858,"score_gpt":0.46936573452629854,"score_spread":0.38844165576777995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2245414184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98849297,0.00016994939,0.00006339921,0.003057295,0.00020011772,0.00013049411,0.00003220933,0.000006143331,0.007847446],"genre_scores_gemma":[0.9964414,0.00020985582,0.002324166,0.00012901732,0.0005877855,0.0000041434855,0.0000025422578,0.000009245565,0.00029183994],"study_design_codex":"design_other","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99445474,0.00018015158,0.004647307,0.00020397107,0.00029742313,0.00021638058],"domain_scores_gemma":[0.99242526,0.002834139,0.0039013543,0.0003350716,0.00031738883,0.00018676977],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022612747,0.00013291604,0.0015441009,0.00009703585,0.000029377372,0.0000036855697,0.00038489437,0.0004162957,0.00017742814],"category_scores_gemma":[0.0055003474,0.000110160705,0.00039060856,0.0001522267,0.00022548232,0.000092639944,0.00004355347,0.0007001641,0.000005018255],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.13910438,0.019514687,0.00034491546,0.000028277655,0.00010567122,0.00010473041,0.0002169371,0.000040795214,0.14196827,0.00052457355,0.0018741214,0.69617265],"study_design_scores_gemma":[0.5187508,0.07474576,0.020290213,0.0004713098,0.00041257212,0.00010905736,0.0003053445,0.00015397591,0.14454909,0.006612655,0.23312208,0.0004771813],"about_ca_topic_score_codex":0.000018935367,"about_ca_topic_score_gemma":0.000014181625,"teacher_disagreement_score":0.69569546,"about_ca_system_score_codex":0.00004880063,"about_ca_system_score_gemma":0.0006854602,"threshold_uncertainty_score":0.6584827},"labels":[],"label_agreement":null},{"id":"W2273629813","doi":"10.1002/jhet.2441","title":"The Effect of Oxidizing Agents in the Preparation of 2,3,5‐<scp>t</scp>riaryl‐2<i>H</i>‐<scp>t</scp>etrazolium Salts from 1,3,5‐<scp>t</scp>riarylformazans","year":2015,"lang":"en","type":"article","venue":"Journal of Heterocyclic Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Oxidizing agent; Formazan; Chloride; Interphase; Dehydrogenation; Salt (chemistry); Combinatorial chemistry; Medicinal chemistry; Organic chemistry; Biochemistry; Catalysis","score_opus":0.019451428891115802,"score_gpt":0.28397025884547966,"score_spread":0.2645188299543639,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2273629813","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98403543,0.00245191,0.00008000492,0.000111143054,0.00024781656,0.00034210124,0.00015095799,0.00004179615,0.0125388615],"genre_scores_gemma":[0.9971575,0.00057196245,0.00024334881,0.000059736223,0.0010252667,0.00008118678,0.000085384956,0.000086411754,0.000689206],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99413353,0.00026186314,0.0025530811,0.0005788134,0.0015975798,0.0008751266],"domain_scores_gemma":[0.98684883,0.007901174,0.0030891902,0.0013950806,0.00035572945,0.00040996462],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0019510109,0.00070307974,0.0012349088,0.00012102379,0.00027547483,0.00018590805,0.002066989,0.00056659774,0.000026804802],"category_scores_gemma":[0.004697677,0.00048440407,0.0007956238,0.00044424905,0.0003333723,0.0004459881,0.00025433674,0.0012648297,0.000021457428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000071553884,0.0004668111,0.006746983,0.00044424043,0.0003997987,0.000031595995,0.0040019066,0.000393168,0.96518725,0.000010104909,0.021643912,0.0006026807],"study_design_scores_gemma":[0.0024514797,0.00015685178,0.001753043,0.00046271377,0.00031488968,0.00018350052,0.004508495,0.000380851,0.9571743,0.0003669385,0.032154005,0.00009294294],"about_ca_topic_score_codex":0.000099957,"about_ca_topic_score_gemma":0.000025337144,"teacher_disagreement_score":0.013122087,"about_ca_system_score_codex":0.00025742658,"about_ca_system_score_gemma":0.0001946551,"threshold_uncertainty_score":0.99976075},"labels":[],"label_agreement":null},{"id":"W2291578267","doi":"10.1016/j.bmc.2016.03.003","title":"Investigation of 4-amino-5-alkynylpyrimidine-2(1H)-ones as anti-mycobacterial agents","year":2016,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"In vivo; Mycobacterium tuberculosis; Chemistry; In vitro; Isoniazid; Tuberculosis; Mycobacterium bovis; Pyrimidine; Pharmacology; Microbiology; Biochemistry; Biology; Medicine; Pathology","score_opus":0.023917057896235067,"score_gpt":0.24278834145666925,"score_spread":0.21887128356043417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2291578267","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99115914,0.00012990416,0.000027461288,0.0011726669,0.00011375651,0.00006734798,0.00007686845,0.000105564824,0.007147315],"genre_scores_gemma":[0.99685234,0.00016177782,0.000069170645,0.000068716276,0.001034951,0.000025317264,0.00006425371,0.000043090437,0.0016803583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99814934,0.000014347855,0.0005836457,0.00045863597,0.0004539532,0.00034007558],"domain_scores_gemma":[0.9984619,0.00013713185,0.00037021827,0.00064032915,0.00013601685,0.00025439617],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001787766,0.0002840949,0.00038278382,0.000029698589,0.00009236907,0.0000142273675,0.00044691438,0.00027113914,0.010263423],"category_scores_gemma":[0.0003235977,0.00021069004,0.00011388103,0.00016872975,0.00034735064,0.00009081873,0.000104543,0.0001373362,0.00016387521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034649125,0.000050581013,0.0046781027,0.00023418294,0.000046355137,0.000005954746,0.000082355386,3.6263305e-8,0.9914959,0.00007418652,0.0013619888,0.0019357133],"study_design_scores_gemma":[0.00076294085,0.000018743202,0.0040614554,0.00034532193,0.000091769245,0.000054184406,0.00017905237,0.0000043945115,0.98968935,0.0003097516,0.0042309286,0.00025209974],"about_ca_topic_score_codex":0.00005461365,"about_ca_topic_score_gemma":7.9631656e-7,"teacher_disagreement_score":0.010099549,"about_ca_system_score_codex":0.00010158565,"about_ca_system_score_gemma":0.00021315683,"threshold_uncertainty_score":0.99064136},"labels":[],"label_agreement":null},{"id":"W2317269400","doi":"10.1158/1538-7445.am2011-4405","title":"Abstract 4405: The novel allosteric Akt inhibitor, MK-2206, synergizes with gefitinib against human glioma cells via promoting the switch from autophagy to apoptosis","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University College of the North","funders":"","keywords":"Gefitinib; Protein kinase B; Apoptosis; Cancer research; Glioma; Epidermal growth factor receptor; Autophagy; Cancer cell; Tyrosine-kinase inhibitor; Biology; Pharmacology; Cancer; Medicine; Internal medicine; Biochemistry","score_opus":0.08596835986222348,"score_gpt":0.33473207182719555,"score_spread":0.24876371196497207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2317269400","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9860202,0.00019931635,0.00003472273,0.0011951404,0.000051297244,0.0005198351,0.00013236697,0.000082441045,0.011764673],"genre_scores_gemma":[0.9967764,0.00004056863,0.00021607104,0.00012343288,0.00069332734,0.0014497008,0.000018005827,0.00008198262,0.00060052733],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972485,0.000060500115,0.00039934268,0.0006677932,0.0008237733,0.000800148],"domain_scores_gemma":[0.9977877,0.00039470114,0.00015416155,0.0011394013,0.0002997933,0.00022422113],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000705207,0.00027811216,0.0002592204,0.00008211184,0.0010221445,0.00021253238,0.0012460402,0.0001351628,0.0018267658],"category_scores_gemma":[0.000047934012,0.00016205582,0.00009976802,0.00055180554,0.00031832818,0.00010719057,0.00035997215,0.0007351163,0.00017812251],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059060036,0.00021712638,0.00011253657,0.00005375745,0.00008570217,0.000005561701,0.0024214939,0.000011372287,0.98637146,0.00009641622,0.0009239765,0.009641554],"study_design_scores_gemma":[0.0003205805,0.000041285228,0.0017099918,0.00021970326,0.000020289754,0.000002009169,0.0010185734,0.00004390491,0.9908854,0.00011612052,0.005380564,0.00024162211],"about_ca_topic_score_codex":0.0044078943,"about_ca_topic_score_gemma":0.00043896097,"teacher_disagreement_score":0.011164146,"about_ca_system_score_codex":0.00018273415,"about_ca_system_score_gemma":0.00018436767,"threshold_uncertainty_score":0.9990857},"labels":[],"label_agreement":null},{"id":"W2320320934","doi":"10.1021/jm501740a","title":"The Discovery of Orally Bioavailable Tyrosine Threonine Kinase (TTK) Inhibitors: 3-(4-(heterocyclyl)phenyl)-1<i>H</i>-indazole-5-carboxamides as Anticancer Agents","year":2015,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"Basic Energy Sciences; Institute of Microbiology, Chinese Academy of Sciences; Canadian Institutes of Health Research; Office of Science; Princess Margaret Cancer Foundation; U.S. Department of Energy","keywords":"Chemistry; Indazole; In vivo; Pharmacology; Sulfonamide; Pharmacokinetics; Structure–activity relationship; IC50; Stereochemistry; In vitro; Biochemistry; Medicine","score_opus":0.022203816229199955,"score_gpt":0.2738940626766925,"score_spread":0.2516902464474925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2320320934","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9818171,0.0048119305,0.00006504608,0.001840143,0.00021179531,0.00006048342,0.000027328473,0.00001878698,0.0111473845],"genre_scores_gemma":[0.99539274,0.000847301,0.00024180519,0.000093939525,0.0015296487,0.000010320208,0.00001000198,0.00003878688,0.0018354724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99696755,0.000025537487,0.0011674453,0.00025934778,0.0011698068,0.00041033098],"domain_scores_gemma":[0.9970386,0.00024343519,0.0012373066,0.0005645373,0.00054396107,0.00037215368],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008139861,0.0003099406,0.00058020354,0.000040549585,0.00014652318,0.00008583812,0.0007382975,0.00017744502,0.0003585229],"category_scores_gemma":[0.0006392831,0.00020438769,0.00025439894,0.00022262504,0.00041605762,0.00026326263,0.00013179831,0.000573139,0.000014370357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043637573,0.0003588242,0.003007223,0.00027402642,0.00019628763,0.00007862367,0.00017484292,0.000031621694,0.980422,0.000056290533,0.011740345,0.0032235354],"study_design_scores_gemma":[0.0015549108,0.00009837548,0.00019222414,0.0007994752,0.00019948155,0.00027528327,0.0011838806,0.00006528397,0.9685946,0.000596387,0.02621256,0.00022752109],"about_ca_topic_score_codex":0.00005954378,"about_ca_topic_score_gemma":0.000004596743,"teacher_disagreement_score":0.014472215,"about_ca_system_score_codex":0.00019171549,"about_ca_system_score_gemma":0.0005661526,"threshold_uncertainty_score":0.8334688},"labels":[],"label_agreement":null},{"id":"W2322879380","doi":"10.1158/1535-7163.targ-09-a142","title":"Abstract A142: Molecular modeling approach to the rational design of promiscuous quinazoline-based EGFR inhibitors","year":2009,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Cancer research; Epidermal growth factor receptor; Tyrosine kinase; Quinazoline; Kinase; Biology; Erlotinib; PTEN; Proto-oncogene tyrosine-protein kinase Src; Receptor tyrosine kinase; Biochemistry; Afatinib; Docking (animal); Chemistry; Pharmacology; Signal transduction; Cell biology; PI3K/AKT/mTOR pathway; Receptor; Medicine; Stereochemistry","score_opus":0.039225374973548,"score_gpt":0.2795693104840613,"score_spread":0.2403439355105133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2322879380","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.31941935,0.0021328472,0.66912514,0.004809226,0.000047111746,0.0007290982,0.000059020706,0.00010210684,0.0035761206],"genre_scores_gemma":[0.9893244,0.00003726672,0.008550743,0.0015875746,0.00011801945,0.000272191,0.000028631786,0.000048636346,0.00003255254],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99827856,0.00003912861,0.00045295458,0.0004037418,0.0004860766,0.0003395413],"domain_scores_gemma":[0.9988437,0.00004053008,0.00016318337,0.00066920585,0.00018635941,0.00009699332],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022902347,0.00027956915,0.00026184594,0.000061091225,0.00013992518,0.000052672123,0.00048515256,0.00014476874,0.00006250856],"category_scores_gemma":[0.000014337937,0.00022362215,0.00018192631,0.0002638564,0.000052875526,0.000036450303,0.000025522279,0.00023387425,0.000009817114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004626375,0.00022949663,0.000006341313,0.000024792098,0.00005456872,0.0000017142548,0.00011267544,0.40784574,0.5849893,0.00096045743,0.00003011868,0.0056985538],"study_design_scores_gemma":[0.00040931767,0.000031733947,0.000032984626,0.00005740135,0.000112465495,0.00000221063,0.000061075305,0.20418146,0.792497,0.00088990445,0.0014271383,0.00029731524],"about_ca_topic_score_codex":0.00003858327,"about_ca_topic_score_gemma":0.0000016690258,"teacher_disagreement_score":0.66990507,"about_ca_system_score_codex":0.00010796241,"about_ca_system_score_gemma":0.0002667631,"threshold_uncertainty_score":0.91190463},"labels":[],"label_agreement":null},{"id":"W2324427724","doi":"10.1097/cad.0b013e328351c101","title":"Enhancement of the cytotoxic potential of the mixed EGFR and DNA-targeting ‘combi-molecule’ ZRBA1 against human solid tumour cells by a bis-quinazoline-based drug design approach","year":2012,"lang":"en","type":"article","venue":"Anti-Cancer Drugs","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Victoria Hospital; McGill University; Royal Victoria Regional Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Quinazoline; Chemistry; Cytotoxic T cell; Apoptosis; Epidermal growth factor receptor; Tyrosine kinase; DNA; Flow cytometry; Molecular biology; Cancer research; Biology; Biochemistry; In vitro; Signal transduction; Receptor; Stereochemistry","score_opus":0.010916177647213534,"score_gpt":0.23779933724543956,"score_spread":0.22688315959822603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2324427724","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99582,0.00072588114,0.0012507057,0.00026473036,0.00010216944,0.00042162315,0.00010628834,0.00002604141,0.0012825651],"genre_scores_gemma":[0.9984512,0.00012058521,0.0004785625,0.0001349954,0.00015786565,0.00015860576,0.000022289054,0.00005064633,0.00042525702],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99793166,0.00012939564,0.00060727354,0.00038020653,0.0004416943,0.00050974573],"domain_scores_gemma":[0.9984202,0.00007848427,0.0006483981,0.000655362,0.00009657868,0.000100995036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004554999,0.00031057297,0.0004181549,0.000035726884,0.00034100024,0.00003127269,0.00064151525,0.000109393724,0.000102607955],"category_scores_gemma":[0.000014309166,0.00021471355,0.00024312164,0.00022641246,0.00031194207,0.000080155005,0.00020302796,0.00024179144,0.000002908982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014418601,0.0006382461,0.00046244168,0.00020799754,0.000064079526,9.0702045e-8,0.00047716417,0.00017951152,0.99566096,0.00008349683,0.0019590585,0.000252543],"study_design_scores_gemma":[0.00067130104,0.000007962301,0.0003583494,0.00012610752,0.00009936066,4.827541e-7,0.00059643807,0.00092532014,0.99636656,0.000019266761,0.0005788906,0.00024998578],"about_ca_topic_score_codex":0.00014769465,"about_ca_topic_score_gemma":0.0000026065406,"teacher_disagreement_score":0.0026311977,"about_ca_system_score_codex":0.00006870262,"about_ca_system_score_gemma":0.0001252176,"threshold_uncertainty_score":0.87557644},"labels":[],"label_agreement":null},{"id":"W2334089285","doi":"10.1021/ml300207a","title":"Novel Inverse Binding Mode of Indirubin Derivatives Yields Improved Selectivity for DYRK Kinases","year":2012,"lang":"en","type":"article","venue":"ACS Medicinal Chemistry Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Genome Canada; Wellcome Trust; GlaxoSmithKline; Ontario Ministry of Research and Innovation; Pfizer; Eli Lilly and Company","keywords":"Selectivity; Moiety; Kinase; Biology; Materials science; Stereochemistry; Biochemistry; Chemistry","score_opus":0.023529605889586334,"score_gpt":0.2723586451505448,"score_spread":0.24882903926095848,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2334089285","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99402463,0.00005238396,0.003390282,0.0011629846,0.000041075065,0.000119397715,0.00011933783,0.00005728616,0.0010326036],"genre_scores_gemma":[0.99670064,0.000008594617,0.0020466181,0.0002456957,0.0005642762,0.00015743809,0.00008517616,0.000034442142,0.00015711995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986453,0.0000068238246,0.00034236663,0.00030033445,0.0002267869,0.00047837454],"domain_scores_gemma":[0.99879086,0.00032237443,0.00029201945,0.00035679084,0.00006362742,0.00017434539],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018310308,0.00024496455,0.0003315642,0.000033429573,0.00012888382,0.000011180411,0.00028082353,0.00016595403,0.0001622695],"category_scores_gemma":[0.0002976318,0.00023646391,0.00011828067,0.00016094187,0.00021048366,0.00014575018,0.00006176337,0.00025203172,0.0000027040462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047135203,0.00021837933,0.0021849042,0.0004691724,0.00007859818,5.2206923e-7,0.0004472095,0.000006255689,0.9946201,0.000025201727,0.0011955099,0.00070701836],"study_design_scores_gemma":[0.000589776,0.000008174445,0.00022527842,0.00010863178,0.00009352194,0.000015145794,0.0006150991,0.00019956628,0.99685305,0.000018036766,0.0010324842,0.00024122701],"about_ca_topic_score_codex":0.00008661675,"about_ca_topic_score_gemma":0.0000031658517,"teacher_disagreement_score":0.0026759896,"about_ca_system_score_codex":0.0001007997,"about_ca_system_score_gemma":0.000057115856,"threshold_uncertainty_score":0.9642718},"labels":[],"label_agreement":null},{"id":"W2347362207","doi":"","title":"The influence of PTD-OD-HA fusion proteins on apoptosis of bcr/abl positive cell lines","year":2010,"lang":"en","type":"article","venue":"Tumori","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Blood Services","funders":"","keywords":"Apoptosis; K562 cells; Fusion protein; breakpoint cluster region; Molecular biology; Flow cytometry; Cell culture; Chemistry; ABL; Fusion gene; Blot; Biology; Cell biology; Cancer research; Signal transduction; Gene; Recombinant DNA; Tyrosine kinase; Biochemistry; Genetics","score_opus":0.005075150973313696,"score_gpt":0.22308337413446963,"score_spread":0.21800822316115592,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2347362207","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9838211,0.000019472856,0.000005257258,0.00030377068,0.00002461573,0.00013790543,0.000047275524,0.000021488702,0.015619106],"genre_scores_gemma":[0.99863636,0.000030653384,0.00028823275,0.000017150142,0.00010346555,0.000072000556,0.0000052068326,0.000013392757,0.0008335073],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99924463,0.000010709786,0.0002557891,0.00016418472,0.00018117567,0.00014353308],"domain_scores_gemma":[0.9989023,0.00020138809,0.00022184856,0.00048897596,0.00014294579,0.00004249812],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011604624,0.00010769857,0.0001460319,0.000019876665,0.00012685159,0.000010796718,0.0002881613,0.000053657943,0.000114476126],"category_scores_gemma":[0.00009173754,0.000075080876,0.00006917825,0.00010047754,0.00013311794,0.00003218127,0.000058837755,0.00019072293,0.000031243824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002462497,0.00016556036,0.00032450713,0.00004835234,0.000005587075,2.3980346e-7,0.00011620703,0.000022373502,0.99561477,0.001914295,0.00006971855,0.0016937595],"study_design_scores_gemma":[0.00011693643,0.000030841864,0.0040926896,0.000060142247,0.000014800023,0.0000010510539,0.000110311834,0.000033555076,0.99342346,0.00034304938,0.0016913811,0.00008176763],"about_ca_topic_score_codex":0.00012960767,"about_ca_topic_score_gemma":0.000013539369,"teacher_disagreement_score":0.014815283,"about_ca_system_score_codex":0.000008931827,"about_ca_system_score_gemma":0.000039445316,"threshold_uncertainty_score":0.3061709},"labels":[],"label_agreement":null},{"id":"W2359707318","doi":"","title":"Chemical constituents from fruits of Euodia rutaecarpa","year":2013,"lang":"en","type":"article","venue":"","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CAE (Canada)","funders":"","keywords":"Rutaecarpine; Evodiamine; Sephadex; Chemistry; Chemical constituents; Chromatography; Tyramine; High-performance liquid chromatography; Silica gel; Ethanol; Organic chemistry; Biochemistry; Enzyme","score_opus":0.009216991736136751,"score_gpt":0.2078300639693296,"score_spread":0.19861307223319286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2359707318","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7962239,0.00003337347,0.00007482935,0.00018253936,0.000012041002,0.00003938346,0.000042459655,0.00003786327,0.20335366],"genre_scores_gemma":[0.9968271,0.0000053497197,0.0017989497,0.000052089472,0.00006931629,0.00004553825,0.000031645573,0.0000083080995,0.0011616771],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994111,0.000002568578,0.00019721572,0.00016068813,0.000106621366,0.00012180864],"domain_scores_gemma":[0.99944216,0.00008681463,0.00005664628,0.00028914664,0.000049531052,0.00007570637],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000015019928,0.00008172437,0.00013996493,0.000010252625,0.000020178388,0.000013971736,0.00016931916,0.0000782687,0.031711455],"category_scores_gemma":[0.00002931043,0.00007019354,0.00005768148,0.000037480528,0.000083445746,0.000045176716,0.000045793,0.000060567658,0.00093601504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000011059927,0.00008504526,0.0023910466,0.000008195854,0.000018408242,1.8289592e-7,0.00002053916,2.6340334e-7,0.986558,0.0020878117,0.004117419,0.004711973],"study_design_scores_gemma":[0.00015561441,8.3106613e-7,0.00068314484,0.000014580311,0.000012548938,6.250002e-7,0.00005850371,0.000084848565,0.99290717,0.0010836932,0.0049094614,0.000088976085],"about_ca_topic_score_codex":0.0005764465,"about_ca_topic_score_gemma":0.0000031367322,"teacher_disagreement_score":0.20219198,"about_ca_system_score_codex":0.000011106916,"about_ca_system_score_gemma":0.000020326004,"threshold_uncertainty_score":0.99984187},"labels":[],"label_agreement":null},{"id":"W2413557253","doi":"10.1016/j.bmcl.2016.06.021","title":"Discovery of 4-(4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)benzamides as novel, highly potent and selective, orally bioavailable inhibitors of Tyrosine Threonine Kinase, TTK","year":2016,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Princess Margaret Cancer Centre","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Potency; Bioavailability; Kinase; Tyrosine kinase; Moiety; Selectivity; Pharmacokinetics; Pharmacology; Stereochemistry; Structure–activity relationship; Threonine; Tyrosine-kinase inhibitor; Cancer; Biochemistry; Enzyme; In vitro; Signal transduction; Serine; Internal medicine; Medicine","score_opus":0.00882445863781131,"score_gpt":0.21039436226077637,"score_spread":0.20156990362296506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2413557253","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921325,0.00086101977,0.0002853043,0.0047126063,0.0000613535,0.00013825066,0.0002005785,0.00006944363,0.0015389848],"genre_scores_gemma":[0.99764794,0.00026944606,0.00034252592,0.00017655782,0.0003990141,0.000026447928,0.00003503823,0.000060492534,0.001042516],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99739724,0.0000139485455,0.0008564781,0.00068916054,0.00056053157,0.0004826243],"domain_scores_gemma":[0.9981028,0.0002655759,0.0006132516,0.00065781106,0.00017106824,0.0001895083],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024229445,0.00043805168,0.0006786053,0.00008913768,0.00009751519,0.000024745916,0.00042388466,0.00023298245,0.00044580863],"category_scores_gemma":[0.00029791327,0.00032329134,0.00015138903,0.00034571998,0.00074741535,0.00018246457,0.00016694104,0.00022041888,0.000014586615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001465879,0.0002687747,0.0024359548,0.00047142158,0.0001379921,0.000009200028,0.00006788645,4.3488635e-7,0.9931532,0.000101672726,0.0015640894,0.0016427571],"study_design_scores_gemma":[0.0016035163,0.000058143898,0.0014654491,0.0006804725,0.00017338802,0.000061856736,0.0001669274,0.0000052722435,0.9942369,0.0000510142,0.0011262049,0.00037087713],"about_ca_topic_score_codex":0.00015610426,"about_ca_topic_score_gemma":0.0000051983457,"teacher_disagreement_score":0.0055155028,"about_ca_system_score_codex":0.00015872825,"about_ca_system_score_gemma":0.00019793081,"threshold_uncertainty_score":0.9999219},"labels":[],"label_agreement":null},{"id":"W2460285354","doi":"10.1055/s-0035-1561481","title":"Modular Synthesis of Quinazolinone-Fused Phenanthridinones by a Palladium-Catalyzed Cascade C–H/N–H Arylation Process","year":2016,"lang":"en","type":"article","venue":"Synthesis","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Science North","funders":"Fundamental Research Funds for the Central Universities; National Natural Science Foundation of China","keywords":"Quinazolinone; Chemistry; Palladium; Intramolecular force; Catalysis; Aryl; Cascade reaction; Combinatorial chemistry; Intermolecular force; Cascade; Tandem; Stereochemistry; Medicinal chemistry; Organic chemistry; Molecule","score_opus":0.010060690408435505,"score_gpt":0.23902418327510702,"score_spread":0.2289634928666715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2460285354","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9852955,0.00042041647,0.00082152477,0.0020378246,0.0000615717,0.00026659557,0.0009403242,0.00027396326,0.00988228],"genre_scores_gemma":[0.997432,0.0003809144,0.0003128991,0.000016300917,0.00022660305,0.00088088814,0.000018531968,0.000114474395,0.0006174175],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99694747,0.00006822142,0.000899986,0.0008308891,0.00060364243,0.0006498202],"domain_scores_gemma":[0.9960678,0.0017000636,0.0006215202,0.0011520229,0.00022457677,0.00023396828],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00036455313,0.00050159154,0.0007793391,0.00016656233,0.0002600863,0.000048604055,0.00076600106,0.0003068493,0.0027427755],"category_scores_gemma":[0.0011690194,0.0003656641,0.00034168537,0.00027052918,0.00042360873,0.00033420094,0.00007964619,0.00012530883,0.00020407555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000973791,0.00043930794,0.0006558833,0.0002974614,0.00017599725,0.0000032545722,0.0002293635,0.0000049170426,0.9449649,0.0008518579,0.00048616694,0.051793527],"study_design_scores_gemma":[0.0003509869,0.000009066862,0.0003175452,0.0005056703,0.00023773471,0.000009082603,0.0003062835,0.00013112514,0.9929597,0.00074947596,0.0038746009,0.0005487667],"about_ca_topic_score_codex":0.0001789277,"about_ca_topic_score_gemma":0.000025020301,"teacher_disagreement_score":0.05124476,"about_ca_system_score_codex":0.00011832025,"about_ca_system_score_gemma":0.00012565144,"threshold_uncertainty_score":0.99987954},"labels":[],"label_agreement":null},{"id":"W25092264","doi":"10.1111/cbdd.12402","title":"1A1-G02 ロボット上部下向きのカメラの画像を用いた自律型移動ロボットの狭所通り抜け走行","year":2002,"lang":"en","type":"article","venue":"ロボティクス・メカトロニクス講演会講演概要集","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Computer science","score_opus":0.024329504920637006,"score_gpt":0.21194684397430777,"score_spread":0.18761733905367076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W25092264","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.322802,0.0019238833,0.0003422807,0.0038207206,0.00024612967,0.00024638698,0.00014984234,0.000944249,0.6695245],"genre_scores_gemma":[0.95863575,0.00043374434,0.0011066968,0.00068079657,0.00089392666,0.00022148514,0.000048136782,0.0001174961,0.03786197],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971152,0.000030552,0.0006465941,0.0008217855,0.00052749127,0.00085837604],"domain_scores_gemma":[0.9976458,0.00020796749,0.00022269187,0.0014301931,0.000113235285,0.00038013593],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00017665171,0.000474062,0.00047442762,0.00012493666,0.0004168626,0.00014555936,0.0007985114,0.00033436934,0.045121226],"category_scores_gemma":[0.00012486841,0.0004668388,0.00032870096,0.00039028563,0.00018036719,0.00023701254,0.00016555138,0.000485397,0.007943782],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000551242,0.0020501034,0.0061639957,0.00034308492,0.00032661099,0.00012584846,0.0013139837,0.00006869785,0.23082541,0.034135282,0.36885363,0.35573825],"study_design_scores_gemma":[0.00087846426,0.000028846629,0.0009379652,0.0000910738,0.000100676814,0.00007166809,0.0003467453,0.002254936,0.0896596,0.0016882189,0.90299517,0.0009466185],"about_ca_topic_score_codex":0.00009710743,"about_ca_topic_score_gemma":0.000027415374,"teacher_disagreement_score":0.63583374,"about_ca_system_score_codex":0.00012068918,"about_ca_system_score_gemma":0.000031253552,"threshold_uncertainty_score":0.99977833},"labels":[],"label_agreement":null},{"id":"W2532369688","doi":"10.1021/acs.jmedchem.6b01083","title":"An Unusual Binding Model of the Methyl 9-Anilinothiazolo[5,4-<i>f</i>] quinazoline-2-carbimidates (EHT 1610 and EHT 5372) Confers High Selectivity for Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases","year":2016,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Structural Genomics Consortium; Agence Nationale de la Recherche; Ministère de l'Enseignement Supérieur et de la Recherche; European Commission; Wellcome; European Federation of Pharmaceutical Industries and Associations; Wellcome Trust","keywords":"Chemistry; Quinazoline; Phosphorylation; Selectivity; Kinase; Tyrosine phosphorylation; Dual (grammatical number); Tyrosine kinase; Structure–activity relationship; Tyrosine; Stereochemistry; Biochemistry; Signal transduction; In vitro","score_opus":0.018903198243474,"score_gpt":0.2601033096729523,"score_spread":0.2412001114294783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2532369688","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99583066,0.00035000127,0.0015821288,0.001552273,0.000070069036,0.00011851026,0.0002359319,0.000026301055,0.00023415871],"genre_scores_gemma":[0.9979935,0.00015043991,0.00087565806,0.000036199875,0.0005271181,0.000014440526,0.000013718453,0.000040460633,0.00034843016],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977515,0.000034931152,0.0009195048,0.000359303,0.00059025176,0.00034450646],"domain_scores_gemma":[0.9968684,0.00066177815,0.0011126744,0.00045610065,0.0006582685,0.00024279229],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007498786,0.00031666117,0.0006389968,0.000054239714,0.00022174309,0.00003044251,0.00041999275,0.00027463585,0.00019523337],"category_scores_gemma":[0.00056650833,0.00019482261,0.00021925561,0.00019198973,0.00044189362,0.00020093091,0.000063883446,0.000373557,6.054734e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003637717,0.00027020037,0.001680327,0.00020232523,0.00011995671,0.0000027763756,0.00011615935,0.00018518498,0.99458706,0.00028022955,0.00033429638,0.0018577252],"study_design_scores_gemma":[0.0017260632,0.00007626834,0.0009837651,0.00038758948,0.00029013125,0.000110928326,0.00027999416,0.0024500585,0.9921482,0.0010694074,0.00024252471,0.00023504501],"about_ca_topic_score_codex":0.000029239583,"about_ca_topic_score_gemma":0.0000046590844,"teacher_disagreement_score":0.002438823,"about_ca_system_score_codex":0.00015934872,"about_ca_system_score_gemma":0.0003403634,"threshold_uncertainty_score":0.7944636},"labels":[],"label_agreement":null},{"id":"W2582444253","doi":"10.5539/ijc.v9n1p73","title":"Synthesis and Characterization of New 8-trifluloromethyl Quinazolin-2,4-(3H)-Dione Nucleosides","year":2017,"lang":"en","type":"article","venue":"International Journal of Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Combinatorial chemistry; Stereochemistry; Characterization (materials science); Medicinal chemistry; Nanotechnology","score_opus":0.01596515955351145,"score_gpt":0.2741642080484686,"score_spread":0.2581990484949571,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2582444253","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923856,0.00011437678,0.00020975001,0.0018407599,0.000110137895,0.00001844129,0.000060374496,0.000009362569,0.0052511427],"genre_scores_gemma":[0.9969625,0.00050159515,0.0006333059,0.000019045405,0.0009155202,0.0000033374379,0.000008635241,0.000018392637,0.00093770854],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99873567,0.00000576794,0.0005738119,0.00015135534,0.00041688795,0.00011651507],"domain_scores_gemma":[0.9976364,0.00011307181,0.0013856043,0.00032871767,0.00040217978,0.0001340728],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018030778,0.00013836047,0.0002842751,0.00004667019,0.00009754374,0.00013199379,0.00081054436,0.00011711501,0.0010653177],"category_scores_gemma":[0.000536433,0.00013150001,0.0001416827,0.000022402875,0.00013127059,0.00029987626,0.000116741874,0.00016802743,0.000004141346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009743233,0.000099019286,0.0022692257,0.000051426152,0.00015684262,0.000010879338,0.00007282167,0.0000012108073,0.96592593,0.000084078405,0.000112058195,0.031119063],"study_design_scores_gemma":[0.00040793515,0.0000056655063,0.013524167,0.00026231597,0.00005946041,0.00013793533,0.000057754594,0.0000265904,0.9795282,0.00050363695,0.0053693857,0.00011695845],"about_ca_topic_score_codex":0.000024946325,"about_ca_topic_score_gemma":7.103206e-7,"teacher_disagreement_score":0.031002106,"about_ca_system_score_codex":0.00004829988,"about_ca_system_score_gemma":0.00011148129,"threshold_uncertainty_score":0.9998478},"labels":[],"label_agreement":null},{"id":"W2731182045","doi":"10.1002/slct.201700889","title":"Copper‐Catalysed Tandem Synthesis of Substituted Quinazolines from Phenacyl Azides and <i>O</i> ‐Carbonyl Anilines","year":2017,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"King Saud University; Institute of Population and Public Health; Department of Science and Technology, Ministry of Science and Technology, India","keywords":"Phenacyl; Chemistry; Imine; Tandem; Yield (engineering); Combinatorial chemistry; Functional group; Condensation; Condensation reaction; Copper; Catalysis; Organic chemistry; Materials science","score_opus":0.01629681386065093,"score_gpt":0.25442477679244785,"score_spread":0.23812796293179692,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2731182045","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9809778,0.000861241,0.000014646199,0.00027730476,0.000029022052,0.000071953,0.00022046745,0.00010555204,0.017442046],"genre_scores_gemma":[0.9982044,0.00033257197,0.00046927272,0.000013684117,0.000420091,0.00009259358,0.00008409652,0.00004367432,0.0003395791],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983513,0.00000864705,0.00047453956,0.00059035164,0.00023325499,0.00034190482],"domain_scores_gemma":[0.9974816,0.00038191958,0.0005084858,0.0013019454,0.00016335459,0.00016272029],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001194669,0.0003402189,0.00058017496,0.000023989063,0.00042583127,0.0001287595,0.00073099294,0.00023974854,0.00032238563],"category_scores_gemma":[0.0009817882,0.00032389764,0.00015193204,0.000073052615,0.00046045647,0.00013674493,0.00015479719,0.00017886066,0.000009987754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003542919,0.0001133633,0.020152718,0.00015340783,0.00011269373,0.000003830062,0.000040118986,0.0000012839705,0.9751212,0.00003966533,0.0004079797,0.0038183355],"study_design_scores_gemma":[0.00044877763,0.0000035507344,0.003900381,0.00017525895,0.00018185975,0.000009218926,0.00008998389,0.00022745969,0.99297124,0.00026714694,0.001381771,0.00034332203],"about_ca_topic_score_codex":0.0004792352,"about_ca_topic_score_gemma":0.000051568193,"teacher_disagreement_score":0.017850094,"about_ca_system_score_codex":0.00003581346,"about_ca_system_score_gemma":0.000098902645,"threshold_uncertainty_score":0.9999213},"labels":[],"label_agreement":null},{"id":"W2732312261","doi":"10.1016/j.bmc.2017.07.010","title":"Synthesis and biological evaluation of fluoro-substituted 3,4-dihydroquinazoline derivatives for cytotoxic and analgesic effects","year":2017,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Cytotoxic T cell; Metabolic stability; Microsome; IC50; Pharmacology; Amide; Combinatorial chemistry; Analgesic; Lead compound; Biological activity; Cytotoxicity; Stereochemistry; In vitro; Biochemistry","score_opus":0.04388298424741217,"score_gpt":0.305459937062448,"score_spread":0.26157695281503585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2732312261","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965255,0.0017489166,0.000152085,0.0003733129,0.000022011629,0.00023626532,0.00005517422,0.00003743292,0.0008492595],"genre_scores_gemma":[0.99877566,0.00028915837,0.00042724487,0.000012149073,0.0002565057,0.00015042648,0.000029466974,0.000021373102,0.00003799091],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986414,0.000021915213,0.00033438,0.0004629598,0.00029687223,0.00024250793],"domain_scores_gemma":[0.9982099,0.00051985314,0.00037891293,0.0005642968,0.00017334902,0.00015370727],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005883691,0.00024012908,0.00042538514,0.000022486398,0.00034680995,0.00003618967,0.00029799176,0.00023271884,0.00030131222],"category_scores_gemma":[0.0029634715,0.00020017166,0.000063991225,0.000048092108,0.0006045126,0.00006997594,0.00010936099,0.00012333096,0.0000014019379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047480073,0.00008643898,0.0019345882,0.00056084926,0.00007201553,0.0000014406095,0.00006498425,1.4468503e-7,0.9806294,0.00007730081,0.000034269324,0.016491126],"study_design_scores_gemma":[0.000981622,0.00002277495,0.019635882,0.00027452028,0.0003293346,0.000026865504,0.00017603967,0.00062457117,0.9770585,0.00050619285,0.00015823472,0.00020547662],"about_ca_topic_score_codex":0.000017040342,"about_ca_topic_score_gemma":0.0000019433855,"teacher_disagreement_score":0.017701294,"about_ca_system_score_codex":0.00005007447,"about_ca_system_score_gemma":0.00009609923,"threshold_uncertainty_score":0.8162764},"labels":[],"label_agreement":null},{"id":"W2734250365","doi":"10.1016/j.phymed.2017.06.006","title":"Pellitorine, an extract of Tetradium daniellii, is an antagonist of the ion channel TRPV1","year":2017,"lang":"en","type":"article","venue":"Phytomedicine","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Szegedi Tudományegyetem; Nemzeti Kutatási és Technológiai Hivatal; Ministry of Health, British Columbia; Hungarian Scientific Research Fund","keywords":"Antagonist; TRPV1; Ion channel; Chemistry; Pharmacology; Biophysics; Transient receptor potential channel; Biochemistry; Medicine; Biology; Receptor","score_opus":0.038299831230607824,"score_gpt":0.3061054339959091,"score_spread":0.2678056027653013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2734250365","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98134804,0.0001664215,0.000041482137,0.0012950769,0.00022771215,0.00009178919,0.000092136004,0.000020253394,0.016717097],"genre_scores_gemma":[0.9976433,0.00012141945,0.00007332907,0.000035935143,0.0012054744,0.000013161911,0.000016158889,0.000019682919,0.0008715503],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899,0.000010895209,0.00032000605,0.00023552848,0.0002750402,0.00016853373],"domain_scores_gemma":[0.9978271,0.000037842674,0.00042474884,0.0015260153,0.00008435575,0.000099907025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016915024,0.00013611357,0.00027632486,0.000024569443,0.00021417296,0.000015547763,0.00071125105,0.00007157377,0.00030505276],"category_scores_gemma":[0.000048273552,0.00009302802,0.00008204791,0.000059401576,0.00031677555,0.00012284749,0.000048027643,0.00014110409,0.0000042260353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003079195,0.00054642855,0.006996952,0.0001803167,0.000023793333,0.0000013478941,0.0006077703,0.0000015138625,0.9824072,0.00012453336,0.0005512043,0.008528136],"study_design_scores_gemma":[0.00037849013,0.0000636996,0.041207742,0.00012196608,0.000052795018,0.0000060463603,0.0002942638,0.0002924801,0.9494561,0.0005999885,0.0074230293,0.00010343129],"about_ca_topic_score_codex":0.00018236553,"about_ca_topic_score_gemma":0.000014630567,"teacher_disagreement_score":0.03421079,"about_ca_system_score_codex":0.000015418793,"about_ca_system_score_gemma":0.000038467995,"threshold_uncertainty_score":0.37935728},"labels":[],"label_agreement":null},{"id":"W2738559110","doi":"10.1139/cjc-2017-0258","title":"Rh(III)-catalyzed oxidative <i>ortho</i>-C–H alkylation of 2,4-diarylquinazoline with potassium alkyltrifluoroborates","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Chemistry; Alkylation; Quinazoline; Catalysis; Potassium; Oxidative phosphorylation; Medicinal chemistry; Substrate (aquarium); Combinatorial chemistry; Organic chemistry","score_opus":0.010943525063298563,"score_gpt":0.22474764536480613,"score_spread":0.21380412030150756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2738559110","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9642081,0.0004854282,0.0001282988,0.0008913015,0.0000348749,0.000051737574,0.00017296908,0.000008776234,0.034018513],"genre_scores_gemma":[0.9981648,0.000042169922,0.00060869876,0.000017283446,0.00030868402,0.0000075264115,0.000052903084,0.000033509223,0.00076444366],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985705,0.000008653441,0.00060619804,0.00021903432,0.0002551393,0.0003404446],"domain_scores_gemma":[0.9964308,0.00007288713,0.0015285742,0.00076762796,0.00059110083,0.00060902466],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022714598,0.00023566748,0.00045148085,0.000063050444,0.0003610855,0.000117372765,0.00078327395,0.00017869352,0.0012363223],"category_scores_gemma":[0.0002285075,0.00020813037,0.00014936694,0.00009105387,0.00041272107,0.00029286355,0.00002498612,0.00034192833,0.000005269495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008629386,0.00006689263,0.009819007,0.00015994614,0.00017356667,0.00008388915,0.00020681442,0.0000689151,0.98523957,0.00009427524,0.00083257933,0.003168273],"study_design_scores_gemma":[0.0009496902,0.00001559823,0.0022381374,0.00027161033,0.00009961119,0.00015503286,0.00030749058,0.00002657202,0.9890427,0.00016236326,0.006486773,0.00024441796],"about_ca_topic_score_codex":0.0014821523,"about_ca_topic_score_gemma":0.0013473994,"teacher_disagreement_score":0.03395668,"about_ca_system_score_codex":0.000111843365,"about_ca_system_score_gemma":0.0014838064,"threshold_uncertainty_score":0.9996767},"labels":[],"label_agreement":null},{"id":"W2754507185","doi":"10.1016/j.bmcl.2017.09.026","title":"Discovery of potent antiviral (HSV-1) quinazolinones and initial structure-activity relationship studies","year":2017,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University Medical Centre; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Stanley Medical Research Institute","keywords":"Herpes simplex virus; Chemistry; Structure–activity relationship; HSL and HSV; Chemical synthesis; Virus; Toxicity; In vitro; Stereochemistry; Pharmacology; Combinatorial chemistry; Virology; Biochemistry; Organic chemistry; Biology","score_opus":0.03927135312393834,"score_gpt":0.3076443799191132,"score_spread":0.26837302679517483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2754507185","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99396574,0.000408024,0.000070103684,0.003991763,0.00008696304,0.00006821366,0.000114798444,0.000039609637,0.0012547704],"genre_scores_gemma":[0.9989023,0.000099562145,0.00010531271,0.0000705169,0.0006243295,0.000012207615,0.000020413307,0.000027956581,0.00013739026],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985662,0.000015390186,0.00035575606,0.000446981,0.0003283619,0.00028732413],"domain_scores_gemma":[0.99835753,0.00018703015,0.00050683937,0.00080200314,0.00006430338,0.00008231539],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014342462,0.00028356878,0.00044404747,0.000024553252,0.00046899993,0.00007163337,0.0004015276,0.0001512927,0.00006260877],"category_scores_gemma":[0.0005144589,0.00025023226,0.000091533424,0.00005049635,0.0009567138,0.00026406653,0.00021051984,0.0003235385,0.000002692918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051218547,0.000054430933,0.014077696,0.00042746673,0.000100522055,0.000015881435,0.00018258565,2.42385e-7,0.9828459,0.000075586875,0.00017383858,0.0019946361],"study_design_scores_gemma":[0.0005352157,0.000008742549,0.04555338,0.00019048447,0.00014019958,0.000044412558,0.000449563,0.000011403315,0.9524887,0.00020385384,0.000120605524,0.00025340798],"about_ca_topic_score_codex":0.00007057286,"about_ca_topic_score_gemma":0.00000724045,"teacher_disagreement_score":0.03147568,"about_ca_system_score_codex":0.00007403393,"about_ca_system_score_gemma":0.00006376428,"threshold_uncertainty_score":0.999995},"labels":[],"label_agreement":null},{"id":"W2765544931","doi":"10.5539/ijc.v9n4p82","title":"Synthesis of 8-Trifluloromethyl-2-Thioquinazolin-(3H)-4-One Nucleosides","year":2017,"lang":"en","type":"article","venue":"International Journal of Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Combinatorial chemistry; Stereochemistry; Coupling (piping)","score_opus":0.019072986149981652,"score_gpt":0.28892929266687917,"score_spread":0.2698563065168975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765544931","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92166626,0.0002205366,0.00012059318,0.0015390222,0.00016703157,0.000019569872,0.000085261585,0.000014120437,0.07616759],"genre_scores_gemma":[0.99626106,0.00030434484,0.0016321364,0.000021252672,0.000983537,0.000007318552,0.0000037633015,0.000025719131,0.0007608893],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99809945,0.000008490821,0.0008093941,0.00017951548,0.00072842906,0.00017471386],"domain_scores_gemma":[0.9962906,0.00028777804,0.0018710089,0.0005974494,0.0008224569,0.00013065293],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00032542774,0.00017070294,0.00039393036,0.000056548866,0.0001253979,0.00013067306,0.0019774926,0.00015660758,0.0034316606],"category_scores_gemma":[0.0014037226,0.00016569416,0.00034002305,0.000028478591,0.00023425311,0.00025913704,0.00017804162,0.00028910823,0.000017584514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013445457,0.0003404321,0.0017946454,0.00009085333,0.00038811742,0.00002855261,0.00004047591,0.000009029663,0.97508615,0.00022105953,0.00046945765,0.021396773],"study_design_scores_gemma":[0.00042795384,0.000006853799,0.0023710856,0.0003876059,0.00008857977,0.00012729634,0.0001050715,0.000022653672,0.98894894,0.0013151377,0.0060477317,0.00015109565],"about_ca_topic_score_codex":0.00002368916,"about_ca_topic_score_gemma":8.4526454e-7,"teacher_disagreement_score":0.0754067,"about_ca_system_score_codex":0.000088825465,"about_ca_system_score_gemma":0.00013147824,"threshold_uncertainty_score":0.9974793},"labels":[],"label_agreement":null},{"id":"W2767402289","doi":"10.1039/c7ra10352b","title":"Synthesis and structure–activity relationship of N<sup>4</sup>-benzylamine-N<sup>2</sup>-isopropyl-quinazoline-2,4-diamines derivatives as potential antibacterial agents","year":2017,"lang":"en","type":"article","venue":"RSC Advances","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Drug Research and Development","funders":"Guangzhou Municipal Science and Technology Project; Guangdong Science and Technology Department; Department of Education of Guangdong Province; Guangdong University of Technology; AstraZeneca","keywords":"Benzylamine; Isopropyl; Quinazoline; Chemistry; Antibacterial activity; Medicinal chemistry; Combinatorial chemistry; Stereochemistry; Bacteria","score_opus":0.018560586582691885,"score_gpt":0.28199473460477625,"score_spread":0.26343414802208437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2767402289","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952418,0.0005117079,0.00029319985,0.00044152307,0.00008219732,0.00024257648,0.00051151146,0.000092690236,0.0025828006],"genre_scores_gemma":[0.9960525,0.00041116832,0.0020259991,0.000013532323,0.0007126213,0.0000742072,0.000052441454,0.00006480274,0.0005927011],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976286,0.000076459175,0.00059143535,0.000788565,0.00042733856,0.00048754763],"domain_scores_gemma":[0.997134,0.0005348144,0.0008141791,0.0011637321,0.0001719261,0.00018138235],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016871013,0.0004898466,0.00068935927,0.000111233625,0.0010060875,0.00021586141,0.00067968626,0.00028222823,0.000804055],"category_scores_gemma":[0.0013524182,0.0004525617,0.00018172513,0.000112213595,0.0006698985,0.0010220536,0.00028079798,0.00028429378,0.000019633526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00089702033,0.0010206624,0.12122979,0.0015330509,0.00051479397,0.000045553465,0.0020440612,0.002965379,0.71363586,0.0062869946,0.0002363811,0.14959046],"study_design_scores_gemma":[0.0012758522,0.00008702028,0.09722057,0.00037315534,0.00030851807,0.00005896508,0.0011734971,0.0061888476,0.8790638,0.007539643,0.0056655393,0.0010446331],"about_ca_topic_score_codex":0.00013642237,"about_ca_topic_score_gemma":0.0000217048,"teacher_disagreement_score":0.16542791,"about_ca_system_score_codex":0.000044370034,"about_ca_system_score_gemma":0.00009728804,"threshold_uncertainty_score":0.99979264},"labels":[],"label_agreement":null},{"id":"W2770595944","doi":"10.1039/c7cc07926e","title":"Catalytic substitution/cyclization sequences of <i>O</i>-substituted Isocyanates: synthesis of 1-alkoxybenzimidazolones and 1-alkoxy-3,4-dihydroquinazolin-2(1<i>H</i>)-ones","year":2017,"lang":"en","type":"article","venue":"Chemical Communications","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; University of Ottawa","keywords":"Alkoxy group; Catalysis; Chemistry; Substitution (logic); Medicinal chemistry; Combinatorial chemistry; Cascade; Organic chemistry; Computer science; Alkyl","score_opus":0.03367485308569272,"score_gpt":0.28931170592015887,"score_spread":0.25563685283446613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2770595944","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98207986,0.0021043965,0.00018260264,0.0016748592,0.000023813745,0.00014769482,0.00031647133,0.00008094321,0.0133893285],"genre_scores_gemma":[0.99463195,0.0019992914,0.0029937227,0.00001522229,0.00003710594,0.00013749042,0.00013307366,0.000025672842,0.000026461821],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984326,0.000030358018,0.0007232376,0.00034254088,0.00023481008,0.00023646805],"domain_scores_gemma":[0.9949114,0.0007383495,0.0008267321,0.0031228822,0.00027900783,0.00012165088],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020390768,0.00023975977,0.0004932775,0.000078889614,0.0006441798,0.00006262665,0.0018567977,0.00021165966,0.00009142466],"category_scores_gemma":[0.0010376712,0.0002390725,0.00014594734,0.00013904787,0.0023713452,0.00025342635,0.0005691658,0.00021838432,0.000015835201],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018446048,0.0003669332,0.0035819034,0.00029250907,0.00007586399,5.065176e-7,0.00018823527,0.000014361076,0.9705432,0.020343326,0.000048261696,0.0045264554],"study_design_scores_gemma":[0.0002384545,0.0000041075677,0.00056014117,0.00029171325,0.00018479797,0.000009756257,0.00018770882,0.0009193138,0.9931653,0.0029373115,0.001251722,0.00024966517],"about_ca_topic_score_codex":0.00029309283,"about_ca_topic_score_gemma":0.00004917506,"teacher_disagreement_score":0.02262211,"about_ca_system_score_codex":0.000042697513,"about_ca_system_score_gemma":0.00009525824,"threshold_uncertainty_score":0.97490937},"labels":[],"label_agreement":null},{"id":"W2771770874","doi":"10.1109/bibm.2017.8217665","title":"Retrieval of promiscuous natural compounds using multiple targets docking strategy: A case study on kinase polypharmacology","year":2017,"lang":"en","type":"article","venue":"","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Impact","funders":"University Grants Commission","keywords":"Protein Data Bank (RCSB PDB); Docking (animal); Imatinib; Virtual screening; Tyrosine kinase; Protein Data Bank; In silico; Chemistry; Protein kinase A; Computational biology; Imatinib mesylate; Drug discovery; Kinase; Biochemistry; Biology; Protein structure; Cancer research; Signal transduction; Medicine","score_opus":0.0655484065733453,"score_gpt":0.3611554260609176,"score_spread":0.2956070194875723,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2771770874","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99575335,0.000041250456,0.000014898634,0.00005434391,0.000076648794,0.00027292906,0.000024454706,0.00004566303,0.0037164907],"genre_scores_gemma":[0.99919116,0.0000012513925,0.00027481208,0.000014514143,0.00015113523,0.000015561964,0.0000046289483,0.000024451287,0.00032248787],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998859,0.000030143432,0.00032957728,0.00034456982,0.0001754006,0.00026130315],"domain_scores_gemma":[0.998704,0.0001146009,0.00032478312,0.00068179355,0.00009034139,0.000084461106],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017052256,0.00018591036,0.00027558257,0.000042901833,0.0006328792,0.00007986353,0.00032726227,0.000081460814,0.00021289228],"category_scores_gemma":[0.00009935767,0.00016031471,0.00008694134,0.000039090744,0.00011626921,0.00007391194,0.00013035866,0.00023050143,0.0000057060456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015466011,0.0011501573,0.013916409,0.000037884827,0.00009618446,0.0006655359,0.00026686525,0.000086285065,0.98244905,0.0000619548,0.00006611281,0.0010489003],"study_design_scores_gemma":[0.0026135098,0.00014677993,0.004126238,0.00003360187,0.00013197614,0.00056256296,0.0039573843,0.019276263,0.96862876,0.00003157928,0.00013931181,0.00035202765],"about_ca_topic_score_codex":0.0015282496,"about_ca_topic_score_gemma":0.00019116729,"teacher_disagreement_score":0.019189978,"about_ca_system_score_codex":0.000052359752,"about_ca_system_score_gemma":0.00006543185,"threshold_uncertainty_score":0.6537444},"labels":[],"label_agreement":null},{"id":"W2790686872","doi":"10.1016/j.ejmech.2018.01.094","title":"Synthesis and biological evaluation of novel quinazoline-4-piperidinesulfamide derivatives as inhibitors of NPP1","year":2018,"lang":"en","type":"article","venue":"European Journal of Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; PROTEO","funders":"Fonds Québécois de la Recherche sur la Nature et les Technologies; Université Laval; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Sulfamide; Chemistry; Quinazoline; Piperidine; Phosphodiesterase; In vitro; Chemical synthesis; Pharmacology; Biochemistry; Stereochemistry; Enzyme; Organic chemistry","score_opus":0.05229545989393195,"score_gpt":0.298357572865839,"score_spread":0.24606211297190708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790686872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97266656,0.000632351,0.00017676104,0.00025387984,0.00003873378,0.00003457986,0.000015810236,0.0000081419075,0.026173169],"genre_scores_gemma":[0.99806243,0.00015030777,0.0007630755,0.00001658749,0.0009334151,0.0000023052203,0.0000028520183,0.000020619482,0.00004838299],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99802405,0.00008833038,0.0009086414,0.00019494878,0.0006282575,0.00015578438],"domain_scores_gemma":[0.9974185,0.00029748504,0.0010591927,0.0002478304,0.0008315929,0.00014538651],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021287724,0.00017783589,0.00040937017,0.00004738357,0.000059269492,0.00000779892,0.00030404137,0.00006531365,0.0007928504],"category_scores_gemma":[0.002741048,0.00013493348,0.00011835336,0.00013115504,0.0006822234,0.00005936325,0.00007538043,0.00021307962,0.0000030130032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012522134,0.00020188933,0.0008726363,0.0001279381,0.000067937406,0.000006287213,0.00029173272,0.0000044317203,0.9847239,0.000025838192,0.00015740347,0.0133947665],"study_design_scores_gemma":[0.00090014597,0.00012318471,0.0034159916,0.00066514604,0.00018538568,0.00023624592,0.0013680286,0.00012969,0.9917751,0.000052193434,0.0010255588,0.00012332096],"about_ca_topic_score_codex":0.000004206711,"about_ca_topic_score_gemma":1.6831862e-7,"teacher_disagreement_score":0.026124787,"about_ca_system_score_codex":0.000034479544,"about_ca_system_score_gemma":0.00013261224,"threshold_uncertainty_score":0.8681156},"labels":[],"label_agreement":null},{"id":"W2790900967","doi":"10.1016/j.bmcl.2018.03.036","title":"One-pot, multicomponent synthesis of 2,3-disubstituted quinazolin-ones with potent and selective activity against Toxoplasma gondii","year":2018,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University Medical Centre; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Stanley Medical Research Institute","keywords":"Toxoplasma gondii; Chemistry; Substituent; Moiety; Stereochemistry; Structure–activity relationship; Parasite hosting; IC50; In vitro; Biochemistry; Biology; Immunology; Antibody","score_opus":0.010415012420662846,"score_gpt":0.21216604131943026,"score_spread":0.20175102889876742,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790900967","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948464,0.00008133826,0.000328305,0.0022624268,0.000030702977,0.00014540122,0.000071470604,0.00011066454,0.0021233147],"genre_scores_gemma":[0.9984317,0.00006263802,0.000668705,0.00014868753,0.00048281485,0.00006884806,0.000020722022,0.000053124844,0.00006276969],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99793524,0.00002497895,0.00040702664,0.0006795148,0.00048034836,0.00047291076],"domain_scores_gemma":[0.99837863,0.0002517138,0.00036334287,0.00058379833,0.00015802032,0.00026446942],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016131098,0.00039719942,0.0005620708,0.000048928083,0.00023100204,0.0000250319,0.0003365035,0.00019279837,0.00029164873],"category_scores_gemma":[0.0001588014,0.00035561412,0.00008821091,0.00024983558,0.00090893597,0.00008726584,0.0001005908,0.00032460078,0.000015457998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027968953,0.00035973694,0.0010716638,0.000400226,0.00022883997,0.000012535912,0.0002522365,0.0000014739358,0.9911358,0.000007663917,0.0001303438,0.0061198287],"study_design_scores_gemma":[0.000740906,0.000030243868,0.0062747374,0.0003785071,0.00021385054,0.0000623981,0.00032051254,0.00013248403,0.9909212,0.0000056428603,0.0005233934,0.00039613998],"about_ca_topic_score_codex":0.00010089188,"about_ca_topic_score_gemma":0.000015170429,"teacher_disagreement_score":0.0057236888,"about_ca_system_score_codex":0.00019074911,"about_ca_system_score_gemma":0.00011827864,"threshold_uncertainty_score":0.9998896},"labels":[],"label_agreement":null},{"id":"W2803949356","doi":"10.3390/molecules23051221","title":"1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) Inhibitors","year":2018,"lang":"en","type":"article","venue":"Molecules","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of North Carolina at Chapel Hill; Biocenter Finland; Ministero dello Sviluppo Economico; University of Cyprus; Ontario Ministry of Economic Development and Innovation; National Cancer Institute; European Federation of Pharmaceutical Industries and Associations; Wellcome Trust; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; Diamond Light Source; Novartis Pharma; China Scholarship Council; A.G. Leventis Foundation; Research Promotion Foundation; Pfizer","keywords":"Kinase; Protein kinase A; Calmodulin; Chemistry; Biochemistry; Enzyme","score_opus":0.01503796313418059,"score_gpt":0.25267313716846396,"score_spread":0.23763517403428336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2803949356","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95884925,0.00032600257,0.0012500893,0.0020920082,0.00012432582,0.0003366782,0.000113461414,0.0002802217,0.036627956],"genre_scores_gemma":[0.99215657,0.000007204376,0.0013830217,0.00022117236,0.0011356022,0.0003043282,0.000047005367,0.000094240735,0.004650866],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99757737,0.000027426007,0.00048564738,0.0007839517,0.00047899,0.00064664165],"domain_scores_gemma":[0.99831754,0.00005632863,0.00019979286,0.00096220704,0.0001493171,0.0003147891],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001522308,0.0004198054,0.00032916167,0.000103099796,0.0003879422,0.00012524589,0.00050510373,0.00025939455,0.0018912093],"category_scores_gemma":[0.00020207973,0.00040840934,0.00017730908,0.00027510017,0.00033795787,0.000105122745,0.00018258629,0.00030315283,0.0014669999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004904621,0.0005194379,0.000118411386,0.00010469832,0.000035520152,0.00005076198,0.00019960044,0.000012580737,0.9916611,0.0046908115,0.00083026773,0.0017277631],"study_design_scores_gemma":[0.0005293986,0.000074012365,0.00013385846,0.0001131053,0.00003922548,0.00003429154,0.00015433697,0.00023715707,0.97971153,0.0016237568,0.01683742,0.00051190745],"about_ca_topic_score_codex":0.0005712095,"about_ca_topic_score_gemma":0.0001657755,"teacher_disagreement_score":0.033307303,"about_ca_system_score_codex":0.00012927472,"about_ca_system_score_gemma":0.00018010911,"threshold_uncertainty_score":0.9998368},"labels":[],"label_agreement":null},{"id":"W2912085292","doi":"10.1139/cjc-2018-0034","title":"Rhodium-catalyzed regioselective <i>ortho</i>-allylation of 2,4-diarylquinazolines with allylic acetate","year":2019,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Regioselectivity; Allylic rearrangement; Rhodium; Catalysis; Tandem; Medicinal chemistry; Organic chemistry; Combinatorial chemistry","score_opus":0.006171366810661859,"score_gpt":0.1937544276805109,"score_spread":0.18758306086984905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2912085292","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9650416,0.00042394365,0.000053816024,0.000387591,0.000025683445,0.000059539343,0.000043613793,0.000009236745,0.033954978],"genre_scores_gemma":[0.99791,0.000031535594,0.000378453,0.000025645659,0.00016451933,0.0000056005374,0.000026676144,0.0000337992,0.0014237612],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998736,0.000009915005,0.00050875,0.00020408677,0.00023234653,0.00030890337],"domain_scores_gemma":[0.99791664,0.000082952516,0.0007069829,0.00038891676,0.00047653145,0.00042796455],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016660074,0.00019837459,0.00039172973,0.00007349214,0.00006737884,0.000031674932,0.00038582014,0.00014443921,0.0013379224],"category_scores_gemma":[0.00007621385,0.00017677863,0.00014898629,0.00021646007,0.00013306699,0.00014935916,0.000011381337,0.0002973754,0.000014058421],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000091023336,0.00004467261,0.016353423,0.00026769438,0.00018943482,0.00003253155,0.00029433778,0.00020970275,0.9807126,0.000093189825,0.00039300934,0.0013183755],"study_design_scores_gemma":[0.0008493061,0.000022798842,0.0018568835,0.00027035913,0.00009052313,0.00030625737,0.00035137116,0.000039043796,0.9868319,0.00018395667,0.008941761,0.000255848],"about_ca_topic_score_codex":0.00042659367,"about_ca_topic_score_gemma":0.0007212231,"teacher_disagreement_score":0.03286841,"about_ca_system_score_codex":0.000117613745,"about_ca_system_score_gemma":0.0014994732,"threshold_uncertainty_score":0.999575},"labels":[],"label_agreement":null},{"id":"W2912186110","doi":"10.1016/j.ejmech.2019.01.052","title":"New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis","year":2019,"lang":"en","type":"article","venue":"European Journal of Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Cancéropôle Grand Ouest; Ministero dello Sviluppo Economico; Ontario Ministry of Economic Development and Innovation; Région Bretagne; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; Chinesisch-Deutsche Zentrum für Wissenschaftsförderung; University of Carthage; Ministère de l'Education Nationale, de l'Enseignement Superieur et de la Recherche; Deutsche Forschungsgemeinschaft; Infrastructures en Biologie Santé et Agronomie; Novartis Pharma; Ontario Genomics Institute; European Federation of Pharmaceutical Industries and Associations; Wellcome Trust; Ontario Genomics; Pfizer","keywords":"DYRK1A; Chemistry; Quinazoline; Kinase; Casein kinase 1; Threonine; Phosphorylation; Biochemistry; Stereochemistry; Protein kinase A; Serine","score_opus":0.01937670700912855,"score_gpt":0.28105914151830474,"score_spread":0.2616824345091762,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2912186110","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9839202,0.001667896,0.00031819785,0.0007134137,0.000030495097,0.000053239008,0.00000931188,0.00001910002,0.01326811],"genre_scores_gemma":[0.99737245,0.00054387125,0.00090115174,0.000038818496,0.0007646958,0.0000022762008,0.000014122502,0.000025092373,0.00033755033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99810296,0.0001169056,0.00068624533,0.00034122553,0.0005253741,0.00022727146],"domain_scores_gemma":[0.99825007,0.00033715597,0.00063472235,0.00026203424,0.00017718336,0.00033884597],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0013931808,0.00024151648,0.0004975441,0.00010056739,0.00009459885,0.000056577792,0.00025687908,0.00008258814,0.0021236734],"category_scores_gemma":[0.00072620163,0.00018736567,0.00014871267,0.0002446611,0.00013221454,0.00011821718,0.00009802671,0.00039878313,0.000019745643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012471105,0.00007081919,0.009114928,0.000106526415,0.0004348421,0.000039808136,0.00032029205,0.00005641209,0.95438796,0.000024526818,0.00036249467,0.034956686],"study_design_scores_gemma":[0.0025768415,0.00020049125,0.011399385,0.0010391282,0.0023925367,0.00087201357,0.0037173387,0.001956782,0.9676194,0.00030286217,0.0072383373,0.0006848691],"about_ca_topic_score_codex":0.000008193196,"about_ca_topic_score_gemma":3.5591364e-7,"teacher_disagreement_score":0.034271818,"about_ca_system_score_codex":0.000061738465,"about_ca_system_score_gemma":0.000109807515,"threshold_uncertainty_score":0.99878854},"labels":[],"label_agreement":null},{"id":"W2922302318","doi":"10.1101/570002","title":"Anti-tubercular activity of novel 4-anilinoquinolines and 4-anilinoquinazolines","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Novartis Pharma; University of North Carolina at Chapel Hill; National Institutes of Health; Ministero dello Sviluppo Economico; Fundação de Amparo à Pesquisa do Estado de São Paulo; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Ontario Ministry of Economic Development and Innovation; Genome Canada; National Institute of Allergy and Infectious Diseases; Pfizer","keywords":"Quinoline; Quinazoline; Mycobacterium tuberculosis; Combinatorial chemistry; Ring (chemistry); Aniline; Stereochemistry; Chemistry; Potency; Amine gas treating; Computational biology; Biochemistry; Tuberculosis; Biology; Medicine; Organic chemistry; In vitro","score_opus":0.018510664541555057,"score_gpt":0.2346054362472281,"score_spread":0.21609477170567304,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922302318","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99544334,0.0014892092,0.00082989037,0.00018278834,0.00032031996,0.000443888,0.00093887653,0.00028642925,0.0000652473],"genre_scores_gemma":[0.99561393,0.00081093254,0.0026084224,0.000039333445,0.0005761844,0.00015875236,9.2816913e-7,0.00018020294,0.000011315709],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99662495,0.000038797156,0.00082035834,0.0014210287,0.00049142505,0.00060342834],"domain_scores_gemma":[0.9957229,0.00018061316,0.000893259,0.0023018264,0.0006439675,0.00025742967],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038959304,0.00081189774,0.0013217484,0.00021380276,0.00015114844,0.00013027801,0.0007674461,0.0010071994,0.00012225888],"category_scores_gemma":[0.0002227284,0.000860933,0.00032510268,0.0002963918,0.00030420412,0.00015497237,0.00086656463,0.00087302,0.00002879109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025250954,0.00057397725,0.009053102,0.0019483884,0.00022387001,0.0000051822494,0.000007209226,0.00047782206,0.9869791,0.00065602496,0.00004140317,0.000008642945],"study_design_scores_gemma":[0.0006507302,0.000016991284,0.037907336,0.0005728385,0.00029746324,6.7207644e-8,0.0000043654386,0.0058601815,0.95203304,0.00000255849,0.0017582204,0.00089622306],"about_ca_topic_score_codex":0.00013976928,"about_ca_topic_score_gemma":0.000002410185,"teacher_disagreement_score":0.034946103,"about_ca_system_score_codex":0.00011876003,"about_ca_system_score_gemma":0.0004860643,"threshold_uncertainty_score":0.99938416},"labels":[],"label_agreement":null},{"id":"W2944628309","doi":"10.1139/cjc-2018-0521","title":"A convenient approach to 2,4-disubstituted quinazoline-3-oxides using active MnO<sub>2</sub> as the oxidant","year":2019,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Quinazoline; Combinatorial chemistry; Organic chemistry","score_opus":0.013288838279446533,"score_gpt":0.21842658789835057,"score_spread":0.20513774961890402,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944628309","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9819464,0.00022080039,0.00010330205,0.0005033018,0.00008121437,0.000118903736,0.00006358616,0.000011289388,0.016951192],"genre_scores_gemma":[0.99890673,0.000011639355,0.00018697313,0.00017758328,0.00039499238,0.000014733082,0.00001082966,0.000038179896,0.00025832557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99844074,0.000015187445,0.00049320183,0.00027958298,0.00028462976,0.0004866532],"domain_scores_gemma":[0.9978599,0.00007989165,0.0003820906,0.000524883,0.00028133692,0.0008718747],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020459773,0.00025172377,0.0003516016,0.00006530667,0.00021429764,0.00009631149,0.0006712243,0.0001665226,0.00045597192],"category_scores_gemma":[0.00016137633,0.00020385836,0.00022429049,0.00024190199,0.00013845565,0.00010848532,0.00003610082,0.00049522583,0.00006454521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030344396,0.000049300877,0.0002031881,0.00007842247,0.00009185216,0.000029792343,0.0004959738,0.00065644045,0.99707353,0.00010592622,0.00034489555,0.0008403445],"study_design_scores_gemma":[0.00033773485,0.000008766195,0.00015915115,0.00016355497,0.00006378255,0.0007629118,0.0018025591,0.00024819883,0.98696345,0.00012130318,0.009108583,0.0002599741],"about_ca_topic_score_codex":0.00061131566,"about_ca_topic_score_gemma":0.00013408734,"teacher_disagreement_score":0.016960334,"about_ca_system_score_codex":0.00045060756,"about_ca_system_score_gemma":0.0017871849,"threshold_uncertainty_score":0.8313103},"labels":[],"label_agreement":null},{"id":"W2949243570","doi":"10.1016/j.bmcl.2006.05.015","title":"7-(Aryl/heteroaryl-2-ylethynyl)-4-phenylamino-3-quinolinecarbonitriles as new Src kinase inhibitors: Addition of water solubilizing groups","year":2006,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Chemistry; Dimethylamine; Aryl; Alkoxy group; Stereochemistry; Thiophene; Pyridine; Chemical synthesis; Carboxamide; Nitro; Enzyme inhibitor; Proto-oncogene tyrosine-protein kinase Src; Kinase; Ring (chemistry); Medicinal chemistry; Enzyme; Organic chemistry; In vitro; Biochemistry","score_opus":0.007205454049731535,"score_gpt":0.20108357520267803,"score_spread":0.1938781211529465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949243570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907675,0.0006293425,0.00016208056,0.0054536397,0.00012459935,0.00014166508,0.00006920483,0.00021474008,0.0024372707],"genre_scores_gemma":[0.99406403,0.000037509362,0.00031531721,0.0004778613,0.0038563313,0.000046036446,0.0007001319,0.00009345286,0.0004093142],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99674636,0.000018932373,0.0009904813,0.00078351126,0.00071683817,0.0007438482],"domain_scores_gemma":[0.99819374,0.00013689879,0.00035786693,0.000845321,0.00010532854,0.00036087033],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020390085,0.0005397149,0.00057884154,0.000076001554,0.00017918198,0.000046301462,0.00054831454,0.00033768927,0.004954715],"category_scores_gemma":[0.00013558878,0.00046881146,0.00028419693,0.00022059612,0.0003572017,0.00014528703,0.00015161226,0.00046475482,0.00011003816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006304256,0.00018693175,0.0002527068,0.00036767207,0.000055623947,0.00003838053,0.00015987386,0.0000044283606,0.9852024,0.00003107189,0.012328061,0.0013098521],"study_design_scores_gemma":[0.0010170684,0.000018539145,0.00017143087,0.0003364268,0.00016505981,0.00009944531,0.00029394624,0.00003055514,0.99197274,0.000393042,0.0049899127,0.0005118062],"about_ca_topic_score_codex":0.00055400346,"about_ca_topic_score_gemma":0.0000060988,"teacher_disagreement_score":0.007338148,"about_ca_system_score_codex":0.00021981512,"about_ca_system_score_gemma":0.00015930312,"threshold_uncertainty_score":0.99977636},"labels":[],"label_agreement":null},{"id":"W2949272218","doi":"10.1016/j.tetlet.2012.03.031","title":"Palladium-catalyzed intermolecular cyclocarbonylation of 2-iodoanilines with N-toluenesulfonyl aldimines","year":2012,"lang":"en","type":"article","venue":"Tetrahedron Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Aldimine; Catalysis; Palladium; Intermolecular force; Organic chemistry; Polymer chemistry; Molecule","score_opus":0.009462618327083012,"score_gpt":0.21720756903629768,"score_spread":0.20774495070921467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949272218","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942128,0.00023936084,0.002007359,0.00078086875,0.00004556353,0.00008985465,0.000014403472,0.000096743526,0.0025130543],"genre_scores_gemma":[0.99818975,0.000013053973,0.0011516872,0.00017688918,0.00023525282,0.000046451532,0.00006637147,0.00004247429,0.00007804268],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988394,0.000015541727,0.00033021762,0.00023556445,0.00023981398,0.00033950864],"domain_scores_gemma":[0.99908227,0.000076246215,0.00019299074,0.000494502,0.00004578716,0.00010818672],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010710809,0.0002148277,0.00025435985,0.00007544034,0.000055457727,0.000015903886,0.0002189924,0.000077374585,0.00028213515],"category_scores_gemma":[0.000027009735,0.00018232166,0.00009712152,0.00016384137,0.0001374959,0.0001459071,0.000033050157,0.000107613974,0.000030219375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039505874,0.00013085039,0.042241335,0.00010388847,0.00006521837,0.0000029299035,0.00019157422,0.000054555003,0.95444494,0.00026008865,0.00020170135,0.002263435],"study_design_scores_gemma":[0.0006454087,0.000015189668,0.03554719,0.00010967593,0.00013610524,0.000037390128,0.00012580684,0.00019131682,0.96021754,0.000018985133,0.00255553,0.00039988657],"about_ca_topic_score_codex":0.00005726025,"about_ca_topic_score_gemma":0.000008813944,"teacher_disagreement_score":0.006694147,"about_ca_system_score_codex":0.00004504154,"about_ca_system_score_gemma":0.000016807206,"threshold_uncertainty_score":0.74348617},"labels":[],"label_agreement":null},{"id":"W2949760049","doi":"10.3987/com-13-s(s)73","title":"Aminophenylpyrrole Synthesis and Application to Pyrrolo[1,2-c]quinazolinone Synthesis","year":2013,"lang":"en","type":"article","venue":"Heterocycles","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Quinazolinone; Chemistry; Combinatorial chemistry; Stereochemistry","score_opus":0.007461417875533969,"score_gpt":0.2210173383922466,"score_spread":0.21355592051671263,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949760049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9870945,0.00016677527,0.00128525,0.001811855,0.000019671363,0.00031936046,0.000048930877,0.00027329987,0.008980337],"genre_scores_gemma":[0.9930823,0.00008243601,0.0023203222,0.00024049166,0.0001925609,0.003700268,0.0000074200284,0.000064088934,0.0003101325],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981663,0.000024738176,0.00041640142,0.00066790753,0.00024320459,0.000481422],"domain_scores_gemma":[0.99820685,0.00047100266,0.00013095004,0.00077957934,0.00007548976,0.00033612768],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00010252287,0.00032032287,0.00037620502,0.000111011424,0.00027898443,0.00014417835,0.00036609758,0.00017797748,0.0016205001],"category_scores_gemma":[0.00015724072,0.00030690595,0.00010188045,0.00013894943,0.000114896015,0.00018980494,0.00016319117,0.00013497066,0.0016170667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015964557,0.00016561415,0.0016339087,0.00010603447,0.00004193349,0.0000010906274,0.00012953862,0.000025597834,0.77492875,0.0005767304,0.00083228486,0.22154255],"study_design_scores_gemma":[0.00014864973,0.000014054995,0.018136153,0.000098261524,0.00009063079,0.000021937096,0.00039776965,0.0015828956,0.9613885,0.0012342219,0.01628187,0.0006050436],"about_ca_topic_score_codex":0.00032463548,"about_ca_topic_score_gemma":0.000030134453,"teacher_disagreement_score":0.22093752,"about_ca_system_score_codex":0.00005716912,"about_ca_system_score_gemma":0.0000132266505,"threshold_uncertainty_score":0.9999383},"labels":[],"label_agreement":null},{"id":"W2949983677","doi":"10.1002/chin.201051161","title":"ChemInform Abstract: One‐Step Synthesis of Quinazolino[3,2‐a]quinazolinones via Palladium‐Catalyzed Domino Addition/Carboxamidation Reactions.","year":2010,"lang":"en","type":"article","venue":"ChemInform","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Domino; Palladium; Catalysis; Combinatorial chemistry; Cascade reaction; Organic chemistry","score_opus":0.011737461814999564,"score_gpt":0.2309616948486637,"score_spread":0.21922423303366412,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949983677","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.18621504,0.0000447646,0.000008003953,0.00025998752,0.00019116129,0.00030303406,0.000400231,0.00030462205,0.81227314],"genre_scores_gemma":[0.98997074,0.00015674866,0.0007130001,0.00003398134,0.0007139233,0.00061325234,0.00082377245,0.00008557301,0.006889003],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965636,2.4776318e-7,0.0015025769,0.00058750197,0.0006580732,0.00068799406],"domain_scores_gemma":[0.9959167,0.00059863675,0.0011521457,0.0015263078,0.0004558676,0.0003503178],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00040159377,0.00055861403,0.00072397594,0.00020805726,0.0003016785,0.00009181077,0.00079720904,0.00067501573,0.020465136],"category_scores_gemma":[0.00058239506,0.00058439904,0.00040861047,0.00039309362,0.0003842062,0.00066385686,0.00015227313,0.0007169051,0.00048075028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000075795964,0.00040507698,0.00005450569,0.0005158752,0.00010854351,0.0000015706129,0.00015634004,3.7355474e-7,0.6421755,0.0012599041,0.002875622,0.35237086],"study_design_scores_gemma":[0.0005782505,0.000008990323,0.0015046904,0.00016219902,0.00017007111,0.000044872915,0.00030945663,0.000065781984,0.9362679,0.0003193893,0.059965223,0.0006031655],"about_ca_topic_score_codex":0.00025727815,"about_ca_topic_score_gemma":0.00008242205,"teacher_disagreement_score":0.80538416,"about_ca_system_score_codex":0.00015898682,"about_ca_system_score_gemma":0.00021067559,"threshold_uncertainty_score":0.99966073},"labels":[],"label_agreement":null},{"id":"W2950055232","doi":"10.1055/s-2008-1067126","title":"A Novel and Efficient Synthesis of 1-Hydroxyquinazolin-4-ones via Tin(II) Chloride Induced Cyclization of 2-Nitrobenzamides and Ketones","year":2008,"lang":"en","type":"article","venue":"Synthesis","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Dalhousie University","keywords":"Chemistry; Tin; Chloride; Combinatorial chemistry; Organic chemistry; Medicinal chemistry","score_opus":0.01783884020490706,"score_gpt":0.22488066763404121,"score_spread":0.20704182742913416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950055232","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965291,0.00026014805,0.00060213875,0.00020479855,0.000022793593,0.0001452584,0.00009641457,0.000064272106,0.0020750535],"genre_scores_gemma":[0.9978503,0.0003615534,0.0014477973,0.00001004252,0.00007142998,0.00014256117,0.0000039774573,0.0000479885,0.000064362684],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982151,0.00002759751,0.0006783666,0.00047129468,0.00031390408,0.00029374892],"domain_scores_gemma":[0.9976666,0.0011109747,0.00045894505,0.0005017828,0.00013849068,0.00012321313],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023739653,0.00030223173,0.0006429903,0.0001817956,0.00030273266,0.0000121419,0.00021633889,0.00020192645,0.00016097953],"category_scores_gemma":[0.00073653786,0.00028516186,0.00012298209,0.0002553454,0.00036902842,0.00008159925,0.00015894185,0.00010699133,0.000003735405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000076414646,0.00048846874,0.0036417716,0.00037450186,0.00009544422,0.000001912019,0.0005164063,0.000068369416,0.9836427,0.000640492,0.000007473825,0.010446066],"study_design_scores_gemma":[0.0002051986,0.000018508079,0.009146756,0.00025338668,0.00016900362,0.000066545064,0.00028490464,0.0020304604,0.9873276,0.00014122343,0.00007361615,0.00028279453],"about_ca_topic_score_codex":0.00030921496,"about_ca_topic_score_gemma":0.000016023905,"teacher_disagreement_score":0.010163272,"about_ca_system_score_codex":0.000028305185,"about_ca_system_score_gemma":0.000052706815,"threshold_uncertainty_score":0.99996006},"labels":[],"label_agreement":null},{"id":"W2950056140","doi":"10.1002/jhet.3585","title":"Synthesis, Characterization, and Biological Evaluation of Novel 3‐(4‐Chlorophenyl)‐2‐(substituted)quinazolin‐4(3<i>H</i>)‐one Derivatives as Multi‐target Anti‐inflammatory Agents","year":2019,"lang":"en","type":"article","venue":"Journal of Heterocyclic Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Horizon College and Seminary","funders":"","keywords":"Chemistry; Anti-inflammatory; Cyclooxygenase; In vitro; Proinflammatory cytokine; Stereochemistry; Biological activity; Inhibitory postsynaptic potential; Enzyme; Combinatorial chemistry; Pharmacology; Biochemistry; Inflammation","score_opus":0.04256222154797923,"score_gpt":0.2844090411574937,"score_spread":0.24184681960951449,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950056140","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99817556,0.00032125835,0.0005117807,0.00013648797,0.00006793009,0.00014783735,0.00006456519,0.00002268876,0.0005518954],"genre_scores_gemma":[0.99787855,0.00036084358,0.0013083895,0.00002689542,0.00023387559,0.000027740625,0.00003825891,0.000031283576,0.000094157804],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99759644,0.000041503514,0.0010692206,0.00035573682,0.00066609477,0.00027098984],"domain_scores_gemma":[0.9973523,0.00019160238,0.0013631396,0.00040805005,0.00051158207,0.00017335],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005018388,0.0002951492,0.00063695665,0.000062804866,0.00009194503,0.00004190809,0.00037723492,0.0002829515,0.0018149987],"category_scores_gemma":[0.0004938494,0.00026372643,0.00020143439,0.00011213667,0.00017460009,0.00024757106,0.00010207646,0.0003068477,0.000013920179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006979449,0.00060570927,0.02291952,0.00027572093,0.00016542689,0.0000023371024,0.00012384824,0.00007760309,0.9742447,0.000007512428,0.000007412479,0.0015003973],"study_design_scores_gemma":[0.0015109904,0.000014266286,0.055721007,0.0003628552,0.00013917516,0.00011807128,0.00018583109,0.0013825991,0.93950224,0.000029318775,0.0007697036,0.0002639406],"about_ca_topic_score_codex":0.0000025413208,"about_ca_topic_score_gemma":1.1748479e-7,"teacher_disagreement_score":0.034742475,"about_ca_system_score_codex":0.000103862985,"about_ca_system_score_gemma":0.000099311554,"threshold_uncertainty_score":0.9999815},"labels":[],"label_agreement":null},{"id":"W2950714616","doi":"10.1002/chin.201031174","title":"ChemInform Abstract: Tandem Palladium‐Catalyzed Addition/Cyclocarbonylation: An Efficient Synthesis of 2‐Heteroquinazolin‐4(3H)‐ones.","year":2010,"lang":"en","type":"article","venue":"ChemInform","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Tandem; Catalysis; Palladium; Carbonylation; Combinatorial chemistry; Organic chemistry; Aerospace engineering; Carbon monoxide","score_opus":0.010722848511637363,"score_gpt":0.2341650335051741,"score_spread":0.22344218499353674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950714616","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.46476057,0.000023512604,0.000001372321,0.00007337561,0.000084473795,0.0001351155,0.00019443681,0.00015987546,0.5345673],"genre_scores_gemma":[0.99686253,0.00002511562,0.00019821683,0.000027203081,0.00046527406,0.00028748545,0.00047975316,0.000057098463,0.0015973217],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99748564,1.229772e-7,0.00097701,0.00046496847,0.00054058124,0.0005316934],"domain_scores_gemma":[0.99723,0.00027779068,0.0006178711,0.001276791,0.00024624536,0.0003513288],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00028908506,0.0004236291,0.00051452767,0.000109374705,0.00021211039,0.000075655014,0.0006816104,0.00046392024,0.0131051475],"category_scores_gemma":[0.00026627575,0.00041293423,0.00028123666,0.00025270254,0.00029750745,0.00028337064,0.00011100371,0.000459093,0.00015292353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000069413756,0.00076492724,0.00024949148,0.00042799342,0.00011591596,0.0000046312875,0.0007079122,0.0000110826895,0.5875332,0.0021243868,0.002412292,0.4055788],"study_design_scores_gemma":[0.0004359139,0.0000075308644,0.001861149,0.00008636547,0.00008289602,0.000026679085,0.00031639205,0.00030985114,0.97939515,0.00015275154,0.016828584,0.0004967605],"about_ca_topic_score_codex":0.000045178258,"about_ca_topic_score_gemma":0.000027680564,"teacher_disagreement_score":0.53296995,"about_ca_system_score_codex":0.00010358974,"about_ca_system_score_gemma":0.00016880262,"threshold_uncertainty_score":0.9998323},"labels":[],"label_agreement":null},{"id":"W2950863007","doi":"10.1002/chin.201612190","title":"ChemInform Abstract: Facile Approaches Toward the Synthesis of N<sup>4</sup>‐Monosubstituted Quinazolin‐2,4‐diamines.","year":2016,"lang":"en","type":"article","venue":"ChemInform","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Chemistry; Combinatorial chemistry; Medicinal chemistry","score_opus":0.03645577567784022,"score_gpt":0.22817228403174677,"score_spread":0.19171650835390655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950863007","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10896485,0.00018317114,0.00000536916,0.0013594395,0.000032951735,0.00025866408,0.00036261597,0.0001957105,0.88863724],"genre_scores_gemma":[0.98321205,0.00016827807,0.00006771534,0.000037230893,0.0002656171,0.00052387465,0.000051081155,0.000046923888,0.015627198],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975699,1.733772e-7,0.00091249245,0.00042797028,0.0004730509,0.0006164131],"domain_scores_gemma":[0.99715513,0.00076851895,0.00048031312,0.0012533928,0.00014283549,0.00019983073],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00029786263,0.00045403355,0.00053360104,0.00007074056,0.00016944195,0.00005384919,0.001074747,0.00033920724,0.0050786994],"category_scores_gemma":[0.0005112525,0.0002677295,0.00035867284,0.0002484538,0.0005260504,0.00035996872,0.00020305105,0.00022254093,0.00032452767],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055930803,0.00019619413,0.00015354344,0.00043340275,0.00014784843,0.0000018775667,0.0013206517,0.0000025794534,0.03330169,0.001267207,0.010735096,0.952384],"study_design_scores_gemma":[0.0003677329,0.000006423945,0.00033215544,0.00017040875,0.00008376773,0.000016814296,0.001825927,0.000047706082,0.9240465,0.0001651933,0.072532244,0.0004050818],"about_ca_topic_score_codex":0.000036616577,"about_ca_topic_score_gemma":0.0000030815197,"teacher_disagreement_score":0.9519789,"about_ca_system_score_codex":0.00015062511,"about_ca_system_score_gemma":0.00015695453,"threshold_uncertainty_score":0.99997747},"labels":[],"label_agreement":null},{"id":"W2951251067","doi":"10.1055/s-0030-1259301","title":"Facile Route for Novel Quinazolinone-Fused Azauracils through Cyclodesulfurization of Thioquinazolinones","year":2011,"lang":"en","type":"article","venue":"Synlett","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institute of Steel Construction","keywords":"Quinazolinone; Chemistry; Combinatorial chemistry; Intramolecular force; Cyanate; Organic chemistry","score_opus":0.0844750742584524,"score_gpt":0.2658805885143652,"score_spread":0.18140551425591278,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951251067","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.80820847,0.00023599065,0.089359425,0.00034761216,0.00020721335,0.00073749205,0.0015514321,0.0003862113,0.09896615],"genre_scores_gemma":[0.9800368,0.00006220498,0.018001916,0.00009063545,0.00023054327,0.0003773811,0.00018027963,0.0000689647,0.0009512849],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979495,0.000013546048,0.0007310694,0.00053230143,0.0002877637,0.00048582235],"domain_scores_gemma":[0.99818784,0.00019337767,0.0004451162,0.0008233056,0.00025335082,0.00009703755],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00019254228,0.00032942824,0.0004772411,0.00006583873,0.00019766587,0.000025145298,0.00050131953,0.0002665321,0.0013134169],"category_scores_gemma":[0.00014345719,0.0003196768,0.0003416658,0.0002148399,0.00015888261,0.00026894175,0.00008243057,0.00015437692,0.00007409081],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015998945,0.0010346281,0.0013746321,0.0004663964,0.00018378928,0.0000014905335,0.0027366136,0.00003571279,0.9292076,0.059185416,0.00072355376,0.004890143],"study_design_scores_gemma":[0.0011977742,0.0000576709,0.0014277716,0.0000873538,0.00016264699,0.00001211247,0.00058475323,0.00041374774,0.9698997,0.0056166253,0.020032845,0.0005069764],"about_ca_topic_score_codex":0.00022086942,"about_ca_topic_score_gemma":0.00002351742,"teacher_disagreement_score":0.17182831,"about_ca_system_score_codex":0.000054177046,"about_ca_system_score_gemma":0.00009522046,"threshold_uncertainty_score":0.99992555},"labels":[],"label_agreement":null},{"id":"W2951939858","doi":"10.1021/jo991922r","title":"Palladium-Catalyzed Cyclocarbonylation of <i>o</i>-Iodoanilines with Heterocumulenes:  Regioselective Preparation of 4(3<i>H</i>)-Quinazolinone Derivatives","year":2000,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":153,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Quinazolinone; Regioselectivity; Palladium; Catalysis; Carbonylation; Organic chemistry; Combinatorial chemistry; Carbon monoxide","score_opus":0.007678549173158862,"score_gpt":0.2337639356637783,"score_spread":0.22608538649061943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951939858","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99547714,0.00053377356,0.0006130043,0.00017410882,0.000007820153,0.00007374269,0.000010714482,0.000015096752,0.0030945737],"genre_scores_gemma":[0.9985229,0.0005476556,0.00038336986,0.0000095848745,0.00016716719,0.000004196155,0.000010626235,0.000029888577,0.00032462657],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99847466,0.00003352138,0.00079611427,0.0001517376,0.000377205,0.00016675459],"domain_scores_gemma":[0.9976766,0.00023514344,0.001165633,0.00044768982,0.0004092621,0.00006568429],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00026976276,0.00020466757,0.00042754627,0.000025497666,0.00007784686,0.000010877076,0.00041132365,0.00011322979,0.0014775016],"category_scores_gemma":[0.00007843236,0.00013943676,0.00011973863,0.00028808997,0.00021766999,0.0001340647,0.000025158966,0.000221543,0.0000024268058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000736503,0.00021832892,0.0009284399,0.00017172447,0.00017617003,0.0000013942433,0.0008585415,0.00026100548,0.995638,0.000004286943,0.000032759202,0.00097281556],"study_design_scores_gemma":[0.0007783335,0.00006208624,0.0010495037,0.00019719028,0.00021365497,0.00020633344,0.0004360764,0.00008355611,0.99655706,0.0001462579,0.00012912898,0.00014079867],"about_ca_topic_score_codex":0.000011403433,"about_ca_topic_score_gemma":0.0000067794567,"teacher_disagreement_score":0.0030457193,"about_ca_system_score_codex":0.00005986805,"about_ca_system_score_gemma":0.00018939296,"threshold_uncertainty_score":0.9994353},"labels":[],"label_agreement":null},{"id":"W2952322056","doi":"10.1002/chin.201336121","title":"ChemInform Abstract: Highly Efficient and Eco‐Friendly Synthesis of 2‐Alkyl and 2‐Aryl‐4,5‐diphenyl‐1H‐imidazoles under Mild Conditions.","year":2013,"lang":"en","type":"article","venue":"ChemInform","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick","funders":"","keywords":"Aryl; Library science; Chemistry; Alkyl; Computer science; Organic chemistry","score_opus":0.009111524529572996,"score_gpt":0.223482331883527,"score_spread":0.214370807353954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952322056","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6214466,0.0002203928,4.5497023e-7,0.00030536987,0.000016499294,0.00014961866,0.000117998534,0.0000680924,0.37767494],"genre_scores_gemma":[0.9965258,0.00018291063,0.00009438528,0.00006134316,0.00007358585,0.00027551898,0.00006619929,0.000032293912,0.0026879485],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983627,8.36771e-8,0.0006267076,0.00034081246,0.00026559856,0.0004040981],"domain_scores_gemma":[0.99842167,0.00035420348,0.0003266197,0.00050897995,0.00013365416,0.00025489976],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011329412,0.0003270437,0.00040211307,0.00008192938,0.00019158055,0.00009030937,0.00024869925,0.00023977927,0.004256263],"category_scores_gemma":[0.000086999346,0.000300115,0.00010745763,0.00012316533,0.00041498014,0.0002502483,0.00014593411,0.00018942865,0.00009846901],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050887695,0.0006248267,0.00043820488,0.0022633104,0.00033776936,0.0000028589466,0.0018772096,0.000012131872,0.4528496,0.009659994,0.030472465,0.5014108],"study_design_scores_gemma":[0.00036631778,0.0000075440703,0.007986897,0.00015380561,0.00008089404,0.00002092124,0.0018207992,0.0001143788,0.9827378,0.00039497003,0.0059246644,0.00039101392],"about_ca_topic_score_codex":0.0001113899,"about_ca_topic_score_gemma":0.000004740006,"teacher_disagreement_score":0.5298882,"about_ca_system_score_codex":0.00006722731,"about_ca_system_score_gemma":0.00006274362,"threshold_uncertainty_score":0.9999451},"labels":[],"label_agreement":null},{"id":"W2952552052","doi":"10.1016/j.bmcl.2005.05.131","title":"2-Aminoquinazoline inhibitors of cyclin-dependent kinases","year":2005,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"NAEJA-RGM Pharmaceuticals (Canada)","funders":"","keywords":"Kinase; Chemistry; Cyclin-dependent kinase; Threonine; Serine; Protein-Serine-Threonine Kinases; Cyclin-dependent kinase 4; Cell cycle; Cell cycle checkpoint; Cyclin; Cancer research; CHEK1; Biochemistry; Phosphorylation; Cell biology; Cyclin-dependent kinase 2; Cell; Protein kinase A; Biology","score_opus":0.008536263674221296,"score_gpt":0.22215646523705243,"score_spread":0.21362020156283112,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952552052","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9863434,0.0005705857,0.00008352025,0.007495033,0.000059121227,0.00007043532,0.00005597939,0.00012630649,0.005195648],"genre_scores_gemma":[0.9963174,0.00008587664,0.00034194923,0.00048416693,0.0019816835,0.000028420409,0.0000662472,0.000050660346,0.00064357975],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977324,0.0000107395,0.000728433,0.0005080503,0.0005755095,0.0004448961],"domain_scores_gemma":[0.9985257,0.00012600182,0.0003509919,0.00068973866,0.00007471185,0.00023287267],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018744121,0.00033585468,0.0004238885,0.000040151786,0.000099166034,0.000016147602,0.00050984416,0.00018733255,0.0048205955],"category_scores_gemma":[0.00013725024,0.00031721342,0.0001674383,0.00018541189,0.0002902641,0.00007464244,0.0001059675,0.00033528305,0.00009328069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002622033,0.00023517614,0.00069216546,0.00022021777,0.00004910605,0.000013681732,0.00009637194,0.000006628552,0.98950475,0.000016723949,0.0035491074,0.0055898335],"study_design_scores_gemma":[0.0006496959,0.00000754129,0.0003012292,0.00014754217,0.00010150968,0.00007047562,0.00028861064,0.000031343054,0.98340577,0.000012013929,0.014681088,0.00030316415],"about_ca_topic_score_codex":0.000042661188,"about_ca_topic_score_gemma":0.000003865365,"teacher_disagreement_score":0.01113198,"about_ca_system_score_codex":0.0001660486,"about_ca_system_score_gemma":0.00008422814,"threshold_uncertainty_score":0.999928},"labels":[],"label_agreement":null},{"id":"W2952607787","doi":"10.1002/chin.200831173","title":"ChemInform Abstract: Palladium‐Catalyzed Cyclocarbonylation of o‐Iodoanilines with Imidoyl Chlorides to Produce Quinazolin‐4(3H)‐ones.","year":2008,"lang":"en","type":"article","venue":"ChemInform","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Palladium; Catalysis; Chemistry; Organic chemistry","score_opus":0.017231734815481625,"score_gpt":0.23092293445666537,"score_spread":0.21369119964118374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952607787","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.68182087,0.00007972822,0.000001481687,0.00021221307,0.000028815657,0.00024013834,0.000039934166,0.00014173363,0.3174351],"genre_scores_gemma":[0.9888145,0.00009812384,0.00020738387,0.000052442363,0.0003942985,0.00023657676,0.0002298809,0.000057918904,0.009908891],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997686,4.382402e-8,0.00081277546,0.0004708096,0.0005246005,0.00050573715],"domain_scores_gemma":[0.9978601,0.00010042091,0.00045209826,0.00097545364,0.00034030687,0.0002716439],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001514867,0.00041823782,0.00051916204,0.000110445726,0.00018157676,0.000029202036,0.00049056875,0.00021278401,0.000920928],"category_scores_gemma":[0.0001648474,0.00036018316,0.00015249442,0.00043560506,0.00021062908,0.0003132806,0.000105616135,0.00022003255,0.00010896204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00078563724,0.00077697384,0.005773507,0.001657202,0.00027551723,0.000025863992,0.0045637987,0.000036685946,0.7632346,0.00046153195,0.0094289165,0.21297975],"study_design_scores_gemma":[0.00057297316,0.000022798251,0.00800228,0.0001388678,0.000049145427,0.00007298798,0.00031333358,0.000015662568,0.98000354,0.000027870261,0.010312699,0.000467839],"about_ca_topic_score_codex":0.00010934115,"about_ca_topic_score_gemma":0.000031148644,"teacher_disagreement_score":0.3075262,"about_ca_system_score_codex":0.00013401007,"about_ca_system_score_gemma":0.00022775705,"threshold_uncertainty_score":0.9999924},"labels":[],"label_agreement":null},{"id":"W2953052877","doi":"10.1002/chin.200234169","title":"ChemInform Abstract: Synthesis of Substituted Quinazolines.","year":2002,"lang":"en","type":"article","venue":"ChemInform","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"NAEJA-RGM Pharmaceuticals (Canada)","funders":"","keywords":"Chemistry; Service (business); Combinatorial chemistry; Information retrieval; Nanotechnology; Business; Computer science; Marketing","score_opus":0.021204204838045592,"score_gpt":0.2317965932223764,"score_spread":0.2105923883843308,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953052877","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.052034393,0.0001840654,1.9625816e-7,0.00013996649,0.000029331783,0.000068450914,0.00007173544,0.00013418317,0.9473377],"genre_scores_gemma":[0.97372174,0.0002045931,0.00006471154,0.000027254087,0.00017221319,0.00012619121,0.000035369936,0.000030295334,0.025617642],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984172,1.8483052e-8,0.0006583248,0.00024234712,0.00030195908,0.00038017292],"domain_scores_gemma":[0.99847716,0.00019185104,0.00033431742,0.00071394735,0.00012529307,0.00015741953],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009556701,0.0002631964,0.00037225027,0.00006412728,0.000093281385,0.000026952948,0.00047046112,0.0002262175,0.03126036],"category_scores_gemma":[0.00023861536,0.0002497931,0.0002085023,0.00021875715,0.00017109826,0.00021969592,0.00007136121,0.0001807677,0.00043073416],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014870834,0.0002807494,0.000081933744,0.00048817616,0.000067150904,0.0000033057117,0.0003282846,4.3418757e-7,0.07700276,0.0011144242,0.022626532,0.89799136],"study_design_scores_gemma":[0.0002057515,0.0000023205084,0.0002194307,0.00008766247,0.000042520332,0.000013859602,0.0001923753,0.000051074036,0.90214527,0.00004781903,0.096725956,0.00026599166],"about_ca_topic_score_codex":0.000030451423,"about_ca_topic_score_gemma":0.000003475834,"teacher_disagreement_score":0.92172,"about_ca_system_score_codex":0.000076574834,"about_ca_system_score_gemma":0.00002948095,"threshold_uncertainty_score":0.9999954},"labels":[],"label_agreement":null},{"id":"W2953064026","doi":"10.1002/jhet.551","title":"Efficient preparation of 3‐substituted quinazolinediones directly from anthranilic acids and isocyanates","year":2010,"lang":"en","type":"article","venue":"Journal of Heterocyclic Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Chemistry; Anthranilic acid; Organic chemistry; Combinatorial chemistry; Filtration (mathematics); Reaction conditions; Catalysis","score_opus":0.006243911406254191,"score_gpt":0.2555321152076063,"score_spread":0.24928820380135214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953064026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980583,0.00052747194,0.000080529564,0.0001497787,0.000086798806,0.00003318787,0.000053357326,0.000018913712,0.0009916548],"genre_scores_gemma":[0.998593,0.00011260459,0.0007642371,0.000006759817,0.00043581976,0.0000057149537,0.000016203527,0.000016644497,0.00004904284],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986654,0.0000075354947,0.0006858947,0.0002065892,0.0002739226,0.00016066118],"domain_scores_gemma":[0.99856853,0.00016472273,0.00066849124,0.0003128801,0.0001489793,0.00013637725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010707697,0.00017765061,0.000376282,0.000033036507,0.00008029006,0.000030423722,0.00023984697,0.00019160654,0.00067113823],"category_scores_gemma":[0.00013824018,0.00015479123,0.00015428067,0.00006712564,0.00016553023,0.000062492494,0.00004775229,0.0003558691,0.0000026973792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008227272,0.00023001798,0.0016582547,0.000088477675,0.00006150788,0.0000039425126,0.00015096868,0.000049502036,0.9963394,0.000009857226,0.000041583036,0.0012842432],"study_design_scores_gemma":[0.0005910669,0.000010706799,0.0011454336,0.000093173796,0.00008230456,0.00010103032,0.00013209437,0.0009275465,0.9953491,0.0001238576,0.0013009711,0.00014273041],"about_ca_topic_score_codex":0.0000281273,"about_ca_topic_score_gemma":0.0000082697225,"teacher_disagreement_score":0.0012593882,"about_ca_system_score_codex":0.000025049978,"about_ca_system_score_gemma":0.000031640502,"threshold_uncertainty_score":0.73484933},"labels":[],"label_agreement":null},{"id":"W2953249106","doi":"10.1002/chin.201531218","title":"ChemInform Abstract: Synthesis of Pyrido[2,1‐b]quinazolin‐11‐ones and Dipyrido[1,2‐a:2′,3′‐d]pyrimidin‐5‐ones by Pd/DIBPP‐Catalyzed Dearomatizing Carbonylation.","year":2015,"lang":"en","type":"article","venue":"ChemInform","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Carbonylation; Catalysis; Combinatorial chemistry; Medicinal chemistry; Stereochemistry; Organic chemistry; Carbon monoxide","score_opus":0.019476589324320646,"score_gpt":0.23861447675376388,"score_spread":0.21913788742944323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953249106","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5320548,0.0006737832,9.893407e-7,0.00028955605,0.000056568664,0.00018622303,0.00021491441,0.00018575806,0.46633744],"genre_scores_gemma":[0.994397,0.00020400363,0.00019398154,0.00002785958,0.00023828883,0.00023648994,0.00025843582,0.00007786091,0.0043660854],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99716556,3.367622e-7,0.001053702,0.00052359456,0.0006270229,0.00062980456],"domain_scores_gemma":[0.9970846,0.00048289428,0.0007856782,0.00087845523,0.00028168963,0.00048667393],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045348535,0.0005521574,0.0007788446,0.00012730922,0.00019883017,0.00012251262,0.00056073506,0.00041197822,0.00070082984],"category_scores_gemma":[0.00070264796,0.0005336836,0.0002085351,0.00029292292,0.00034722837,0.00061771745,0.00023972074,0.0002565351,0.000071176924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022072443,0.0006813621,0.0019628238,0.002419301,0.00041176227,0.000008260443,0.0040281885,0.0000064180977,0.55494124,0.0025985867,0.053680964,0.3790404],"study_design_scores_gemma":[0.00069345994,0.000010592841,0.00061866984,0.00020809067,0.00015287456,0.000034481694,0.0026331875,0.00009451585,0.96800023,0.00022539902,0.026713815,0.0006146643],"about_ca_topic_score_codex":0.00023655735,"about_ca_topic_score_gemma":0.000015720696,"teacher_disagreement_score":0.46234223,"about_ca_system_score_codex":0.00017501031,"about_ca_system_score_gemma":0.00017753936,"threshold_uncertainty_score":0.99971145},"labels":[],"label_agreement":null},{"id":"W2971532095","doi":"10.1101/757047","title":"Design and analysis of the 4-anilino-quin(az)oline kinase inhibition profiles of GAK/SLK/STK10 using quantitative structure activity relationships","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium","funders":"Engineering and Physical Sciences Research Council; China Scholarship Council; Novartis Pharma; University of North Carolina at Chapel Hill; Biocenter Finland; Ministero dello Sviluppo Economico; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Ontario Ministry of Economic Development and Innovation; Pfizer","keywords":"Kinome; Cyclin-dependent kinase 2; Cyclin-dependent kinase 9; Kinase; Chemistry; MAP2K7; MAP kinase kinase kinase; c-Raf; Mitogen-activated protein kinase kinase; Threonine; Protein kinase A; Biochemistry; Serine; Phosphorylation","score_opus":0.039789380331876976,"score_gpt":0.2571070083545006,"score_spread":0.21731762802262364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2971532095","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868856,0.00035928027,0.010380395,0.00005881744,0.00008826521,0.0005853099,0.0015815385,0.000054755827,0.000006021672],"genre_scores_gemma":[0.9877266,0.00006334857,0.012004344,0.000007420638,0.000072927774,0.000057321504,0.0000026123842,0.000062294326,0.0000030881345],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99761635,0.00027139662,0.0006810606,0.0007782946,0.0003869305,0.00026596527],"domain_scores_gemma":[0.99596214,0.00042501642,0.0014618286,0.0014504592,0.000606405,0.000094120056],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005816017,0.00042765462,0.00084398215,0.0003033122,0.00021410995,0.00005767342,0.0003309524,0.0005952284,0.00008018558],"category_scores_gemma":[0.0003520921,0.00037711157,0.00027115375,0.0010065326,0.00027410898,0.0001306217,0.00034471753,0.0007918438,0.0000015097247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004953639,0.00013677929,0.018362483,0.0006243541,0.0006601148,8.885004e-7,0.000044195924,0.0055455463,0.9738452,0.0007239937,0.000005193565,0.0000017240214],"study_design_scores_gemma":[0.00019938893,0.000011159025,0.08393375,0.00039593998,0.0017124466,1.12164e-8,0.00001943171,0.027087927,0.88627386,0.000015919226,0.000014588738,0.00033557572],"about_ca_topic_score_codex":0.000085760585,"about_ca_topic_score_gemma":0.0000066697435,"teacher_disagreement_score":0.08757132,"about_ca_system_score_codex":0.00016237883,"about_ca_system_score_gemma":0.0004443289,"threshold_uncertainty_score":0.9998681},"labels":[],"label_agreement":null},{"id":"W2971646627","doi":"10.1515/zkri-2019-0029","title":"Synthesis, molecular packing and anti-cholinesterase activity of some new C-2 N-substituted anthranilamide derivatives","year":2019,"lang":"en","type":"article","venue":"Zeitschrift für Kristallographie - Crystalline Materials","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Intramolecular force; Benzamide; Chemistry; Hydrogen bond; Molecule; Stereochemistry; Intermolecular force; Crystal structure; Crystallography; Organic chemistry","score_opus":0.01031758718681249,"score_gpt":0.2548440508449846,"score_spread":0.24452646365817213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2971646627","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963735,0.00057220587,0.00052781624,0.00030850386,0.00009596827,0.00040437,0.00040982943,0.00019471596,0.0011131357],"genre_scores_gemma":[0.99739236,0.00081133813,0.0011901702,0.00004895868,0.00019218637,0.000060224673,0.00010302111,0.00010203316,0.0000997007],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972172,0.00009575712,0.0008869305,0.0008402428,0.00039148665,0.0005683805],"domain_scores_gemma":[0.9977324,0.0002969541,0.0006591866,0.0009349059,0.0001307578,0.0002457835],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00034815405,0.0005749879,0.0011014574,0.00028029893,0.00014560552,0.00017399156,0.00043464877,0.00030665495,0.001345749],"category_scores_gemma":[0.00017081734,0.0005465047,0.0002211678,0.00038347873,0.00036400213,0.00046656025,0.00022687997,0.00018907146,0.000015336724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013227311,0.0002798412,0.0018590599,0.00061952556,0.00019196111,0.000018748346,0.00007952141,0.0000433953,0.98642176,0.009552123,0.000032824337,0.0007689497],"study_design_scores_gemma":[0.0008615377,0.000025142444,0.0048963316,0.00035680292,0.00014143578,0.000022440881,0.0000899294,0.000027303084,0.9878353,0.0003615106,0.004783182,0.00059908116],"about_ca_topic_score_codex":0.00030163216,"about_ca_topic_score_gemma":0.0000114254835,"teacher_disagreement_score":0.0091906125,"about_ca_system_score_codex":0.000007673637,"about_ca_system_score_gemma":0.000096089556,"threshold_uncertainty_score":0.99969864},"labels":[],"label_agreement":null},{"id":"W2982397273","doi":"10.1038/s41598-019-52108-6","title":"Novel dihydroartemisinin dimer containing nitrogen atoms inhibits growth of endometrial cancer cells and may correlate with increasing intracellular peroxynitrite","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Children's Hospital","funders":"State Key Laboratory of Drug Research; China Scholarship Council; Canadian Institutes of Health Research; Science and Technology Commission of Shanghai Municipality","keywords":"Dihydroartemisinin; Peroxynitrite; Sodium pyruvate; Apoptosis; Chemistry; In vivo; Intracellular; Pharmacology; Context (archaeology); IC50; Cancer research; Artemisinin; Biochemistry; Medicine; Biology; In vitro; Immunology; Enzyme","score_opus":0.010299669661761183,"score_gpt":0.22258224445036415,"score_spread":0.21228257478860296,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982397273","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965062,0.0004976224,0.00009432045,0.000032559576,0.0004930084,0.00025396506,0.000030874653,0.000041565294,0.0020498985],"genre_scores_gemma":[0.9981732,0.000014970634,0.0006343032,0.000006971336,0.000081309445,0.000034635985,0.000036356047,0.000035094516,0.000983189],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977099,0.000025054016,0.00064203504,0.000775336,0.00050865527,0.0003390564],"domain_scores_gemma":[0.998126,0.00020659534,0.0006764877,0.00062208826,0.00021486497,0.0001539778],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011080907,0.00021739458,0.0004022448,0.00015828143,0.00020045706,0.00015329126,0.00012758911,0.000121035366,0.00040746067],"category_scores_gemma":[0.00011879063,0.00018489026,0.00008383147,0.0004902008,0.0003176577,0.00016431704,0.00009834333,0.0002021377,0.000012353195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000078838355,0.00008884521,0.05923069,0.00008015342,0.000058101126,0.000019043244,0.00029299248,0.000022844346,0.9394858,0.00009337329,0.00004749363,0.0005018121],"study_design_scores_gemma":[0.00077012024,0.000022653532,0.00033078884,0.00026358245,0.0000975216,0.00020565673,0.00021121398,0.00034499489,0.99559665,0.00025938792,0.0016454264,0.0002519765],"about_ca_topic_score_codex":0.00046655277,"about_ca_topic_score_gemma":0.000012201836,"teacher_disagreement_score":0.0588999,"about_ca_system_score_codex":0.00005023442,"about_ca_system_score_gemma":0.0001718302,"threshold_uncertainty_score":0.7539606},"labels":[],"label_agreement":null},{"id":"W2987782326","doi":"10.1002/cmdc.201900521","title":"Design and Analysis of the 4‐Anilinoquin(az)oline Kinase Inhibition Profiles of GAK/SLK/STK10 Using Quantitative Structure‐Activity Relationships","year":2019,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of North Carolina at Chapel Hill; Innovative Medicines Initiative; Canada Foundation for Innovation; Ontario Ministry of Economic Development and Innovation; Wellcome Trust; Genome Canada; AbbVie; Pfizer; Boehringer Ingelheim","keywords":"Kinome; Kinase; Cyclin-dependent kinase 9; Cyclin-dependent kinase 2; MAP kinase kinase kinase; MAP2K7; Threonine; Cyclin-dependent kinase 4; Protein kinase A; Chemistry; Serine; Computational biology; Biochemistry; Biology; Phosphorylation","score_opus":0.05604186488672748,"score_gpt":0.2823892239915205,"score_spread":0.22634735910479303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2987782326","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966901,0.00009409792,0.002312949,0.00008160337,0.000014551505,0.0002124265,0.00013582138,0.000017114226,0.00044133083],"genre_scores_gemma":[0.9943674,0.000008837656,0.005449792,0.0000065665895,0.000018836588,0.000013510341,0.000039960185,0.000017212471,0.000077848665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989051,0.00006493747,0.0003535552,0.00030677146,0.00021754761,0.0001520528],"domain_scores_gemma":[0.99834377,0.0004585775,0.0004782682,0.00051360583,0.00015824636,0.00004751667],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025718976,0.00016216264,0.00038118052,0.00009618586,0.0001059211,0.000011956846,0.00012808481,0.00015385576,0.00028714768],"category_scores_gemma":[0.00018337135,0.00012887247,0.00014661362,0.00063626503,0.00018451166,0.000101788304,0.00007468998,0.0002204213,0.0000018129991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000394088,0.00009198949,0.013688356,0.00014455375,0.00021488064,1.5400639e-7,0.000434775,0.0009096816,0.98307556,0.0011881088,0.00000747432,0.00020504947],"study_design_scores_gemma":[0.0002268872,0.000009340396,0.01259952,0.00006950637,0.00056215224,0.0000014464678,0.0003799477,0.025777407,0.9595524,0.0006855884,0.000007766823,0.00012805671],"about_ca_topic_score_codex":0.000042263382,"about_ca_topic_score_gemma":0.000010812678,"teacher_disagreement_score":0.024867725,"about_ca_system_score_codex":0.000054037133,"about_ca_system_score_gemma":0.00006995783,"threshold_uncertainty_score":0.5255267},"labels":[],"label_agreement":null},{"id":"W3005561851","doi":"10.1002/slct.202000137","title":"Synthesis of 2‐Cyanoquinazolin‐4‐ones from 3′,5′‐Dichloro‐1 <i>H</i> ‐spiro(quinazoline‐2,4′‐[1,2,6]thiadiazin)‐4(3 <i>H</i> )‐ones","year":2020,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministry of Agriculture - Saskatchewan","keywords":"Triphenylphosphine; Quinazoline; Iodide; Chemistry; Medicinal chemistry; Stereochemistry; Catalysis; Organic chemistry","score_opus":0.014812053670742936,"score_gpt":0.21679841080651385,"score_spread":0.20198635713577093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3005561851","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94065577,0.0016796419,0.00031852743,0.003169762,0.00008388913,0.00022013819,0.0009661354,0.00060267455,0.052303474],"genre_scores_gemma":[0.995181,0.0004119859,0.001486312,0.00052587164,0.0014024618,0.00025346153,0.00022450315,0.00015226091,0.00036214018],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9960476,0.000032211938,0.0011849323,0.0012425343,0.000658211,0.0008344796],"domain_scores_gemma":[0.99651253,0.00078251655,0.00065142,0.0011808232,0.00026345704,0.0006092333],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001581128,0.00072505034,0.001156151,0.000050294686,0.00023110809,0.00007951543,0.0013097068,0.0005075855,0.004004323],"category_scores_gemma":[0.0008631897,0.00076341303,0.0005336136,0.0006366076,0.0003453248,0.00016748864,0.0002549413,0.00056034274,0.00031478395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015949803,0.00031859803,0.0019822777,0.0004977434,0.0002120966,0.000015237791,0.0002708998,0.000025891472,0.9826709,0.00015088897,0.0057799965,0.007915988],"study_design_scores_gemma":[0.00064481766,0.000026115862,0.00018879869,0.00016660702,0.00027929645,0.000012562834,0.00030883736,0.0003082386,0.95554864,0.0002786658,0.041474134,0.0007632964],"about_ca_topic_score_codex":0.00017542474,"about_ca_topic_score_gemma":0.000009805131,"teacher_disagreement_score":0.054525245,"about_ca_system_score_codex":0.00009105659,"about_ca_system_score_gemma":0.00026397218,"threshold_uncertainty_score":0.9994817},"labels":[],"label_agreement":null},{"id":"W3006725389","doi":"10.1016/j.ejmech.2020.112185","title":"Comparative analysis of the dual EGFR-DNA targeting and growth inhibitory properties of 6-mono-alkylamino- and 6,6-dialkylaminoquinazoline-based type II combi-molecules","year":2020,"lang":"en","type":"article","venue":"European Journal of Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Group for Research in Decision Analysis; McGill University Health Centre","funders":"Canadian Institutes of Health Research; McGill University Health Centre; Institut de recherche, Centre universitaire de santé McGill","keywords":"Chemistry; DNA; Molecule; Inhibitory postsynaptic potential; Stereochemistry; Dual (grammatical number); In vitro; Combinatorial chemistry; Biochemistry; Organic chemistry","score_opus":0.02444608287194988,"score_gpt":0.2236019890308777,"score_spread":0.1991559061589278,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3006725389","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934775,0.0024196678,0.000039299237,0.0010131745,0.000020978134,0.000040687253,0.00002035672,0.000008553822,0.0029597601],"genre_scores_gemma":[0.99932134,0.00008341525,0.00019182063,0.000099678844,0.000245073,8.1991425e-7,0.000006494775,0.00001717046,0.00003421206],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99829054,0.000103757804,0.00082661567,0.0002090226,0.00040972064,0.0001603586],"domain_scores_gemma":[0.9981845,0.000111676236,0.0009762874,0.00018197045,0.00036916544,0.00017640162],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004720111,0.00020560251,0.00063400815,0.00004834075,0.00012342737,0.000014175431,0.00029394226,0.00004618724,0.00008790956],"category_scores_gemma":[0.0003592129,0.0001419199,0.0001656459,0.00033014434,0.00055750954,0.000048450358,0.00015279626,0.00036651836,4.135433e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019724405,0.0001120444,0.003318253,0.00043477167,0.00038118626,0.00001759262,0.0014867136,0.000061918225,0.9934645,0.000020368554,0.00025730953,0.0002480849],"study_design_scores_gemma":[0.0008265936,0.00012405596,0.0050745765,0.00039379852,0.0009308794,0.000023749846,0.0018232197,0.0006564832,0.989649,0.000004223822,0.00034770434,0.00014569456],"about_ca_topic_score_codex":0.0000046996265,"about_ca_topic_score_gemma":3.2908426e-7,"teacher_disagreement_score":0.005843793,"about_ca_system_score_codex":0.000019373983,"about_ca_system_score_gemma":0.00011344893,"threshold_uncertainty_score":0.57873255},"labels":[],"label_agreement":null},{"id":"W3008055094","doi":"10.1002/vjch.201900092","title":"Efficient Synthesis of RuO<sub>2</sub> Nanoparticle with excellent activity for one‐pot Synthesis of 2,3‐disubstituted quinazolin‐4(1H)‐ones","year":2019,"lang":"en","type":"article","venue":"Vietnam Journal of Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Horizon College and Seminary","funders":"National Natural Science Foundation of China","keywords":"Nanoparticle; Combinatorial chemistry; Nanotechnology; One-pot synthesis; Chemistry; Materials science; Organic chemistry; Catalysis","score_opus":0.009523490633328024,"score_gpt":0.2186279872081534,"score_spread":0.20910449657482538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3008055094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974338,0.000262355,0.00035617486,0.00023914062,0.00004536899,0.00020803728,0.00013114928,0.000023964529,0.0013000476],"genre_scores_gemma":[0.9985898,0.00013057096,0.00093268394,0.0000048550223,0.00014903271,0.000087104636,0.0000027425515,0.00005845885,0.000044723216],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974062,0.000030198367,0.0010626602,0.0003819329,0.0006825829,0.00043644937],"domain_scores_gemma":[0.99584496,0.0008626977,0.0017383632,0.00073746836,0.0005901617,0.00022636121],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005161581,0.00036053665,0.0010368106,0.000074575,0.00010520481,0.000029421164,0.00056357204,0.00022580264,0.00031588168],"category_scores_gemma":[0.0004011408,0.00030877424,0.0004936438,0.00025482778,0.00023445209,0.00010832644,0.000077374505,0.00026943142,0.00000953226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00088893273,0.001711771,0.00066520716,0.0019052401,0.0003457522,0.0000037518696,0.00009095797,0.0014892922,0.985623,0.000025811287,0.00003844967,0.0072118253],"study_design_scores_gemma":[0.0008675417,0.00006262926,0.00038868276,0.0012122199,0.00048347237,0.000052877967,0.00044987802,0.00081915135,0.995158,0.00003346474,0.00014231908,0.0003297252],"about_ca_topic_score_codex":0.000005648004,"about_ca_topic_score_gemma":0.000001423705,"teacher_disagreement_score":0.009535029,"about_ca_system_score_codex":0.00012109464,"about_ca_system_score_gemma":0.00029588037,"threshold_uncertainty_score":0.99993646},"labels":[],"label_agreement":null},{"id":"W3016002207","doi":"10.1039/c9ra10303a","title":"Aerobic oxidative synthesis of quinazolinones and benzothiazoles in the presence of laccase/DDQ as a bioinspired cooperative catalytic system under mild conditions","year":2020,"lang":"en","type":"article","venue":"RSC Advances","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatoon Medical Imaging; University of Saskatchewan","funders":"","keywords":"Laccase; Catalysis; Oxidative phosphorylation; Chemistry; Combinatorial chemistry; Organic chemistry; Biochemistry; Enzyme","score_opus":0.02152930992070579,"score_gpt":0.2742998503631646,"score_spread":0.25277054044245884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016002207","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924898,0.0019536433,0.00013988477,0.0013975521,0.000010856206,0.00027441085,0.0003728307,0.000034217945,0.0033268167],"genre_scores_gemma":[0.9991443,0.00028697422,0.0002151037,0.000068541674,0.000034571913,0.00019710037,0.000019414914,0.000013440486,0.000020515166],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988753,0.00006371792,0.00040835512,0.00029776787,0.0001923648,0.00016247066],"domain_scores_gemma":[0.99819267,0.0011121097,0.00026628404,0.00026656798,0.000093448994,0.00006891695],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010395145,0.00017222777,0.00036759587,0.000042575124,0.0001121974,0.000017821641,0.00028902866,0.000064400905,0.00006224825],"category_scores_gemma":[0.00027975926,0.00012788193,0.000059646238,0.00029934346,0.00037827442,0.00018542056,0.000055224165,0.00011397522,0.000008446077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025049216,0.000785492,0.0032464263,0.00353532,0.00025709046,0.000021172646,0.014504252,0.0027786242,0.856587,0.11527017,0.00022421093,0.0025397409],"study_design_scores_gemma":[0.00035314352,0.000054505654,0.0014346318,0.00058061624,0.000109445806,0.000014510119,0.03562842,0.0008692168,0.959907,0.00044485892,0.0003795176,0.00022414097],"about_ca_topic_score_codex":0.00013577497,"about_ca_topic_score_gemma":0.00010397681,"teacher_disagreement_score":0.11482531,"about_ca_system_score_codex":0.000021480666,"about_ca_system_score_gemma":0.00007802483,"threshold_uncertainty_score":0.52148736},"labels":[],"label_agreement":null},{"id":"W3016022266","doi":"10.3390/molecules25071697","title":"New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I–Interacting Kinase (TNNi3K)","year":2020,"lang":"en","type":"article","venue":"Molecules","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Engineering and Physical Sciences Research Council; University of North Carolina at Chapel Hill; Biocenter Finland; Ministero dello Sviluppo Economico; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; University of Southampton; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Ontario Ministry of Economic Development and Innovation; Novartis Pharma; China Scholarship Council; Pfizer","keywords":"Kinase; Chemistry; Quinazoline; Troponin I; Stereochemistry; Biochemistry; Medicine; Internal medicine","score_opus":0.010882800776950837,"score_gpt":0.24742130759235798,"score_spread":0.23653850681540714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016022266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9824836,0.001320271,0.00037692394,0.0015817272,0.00007199223,0.00008605153,0.000010488966,0.00011060344,0.013958323],"genre_scores_gemma":[0.995839,0.00007465327,0.0029448152,0.00013479458,0.00057480135,0.000021181138,0.00002695625,0.00004192594,0.00034188232],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998732,0.000023927172,0.00042692042,0.00037866237,0.00023386376,0.00020466978],"domain_scores_gemma":[0.99903727,0.00012118722,0.00020279431,0.00033121963,0.0000799059,0.00022763984],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003418079,0.00021844004,0.00034062815,0.00004154051,0.000093679075,0.00003575139,0.00027076527,0.000108978624,0.0004984976],"category_scores_gemma":[0.00024959125,0.00020891099,0.00022038449,0.00019149594,0.000053112544,0.000082866485,0.00012244507,0.00018516534,0.0001565707],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035083813,0.000056279525,0.00030416448,0.00010102564,0.00005010435,0.000008075563,0.0015764346,0.000040574963,0.9763281,0.0017757833,0.0021696032,0.01755477],"study_design_scores_gemma":[0.00016548808,0.000030781477,0.000080097074,0.00007491766,0.000048968137,0.0000014568445,0.0009453515,0.00027880628,0.95397526,0.000488779,0.04370132,0.00020876354],"about_ca_topic_score_codex":0.00040785866,"about_ca_topic_score_gemma":0.000012057293,"teacher_disagreement_score":0.04153172,"about_ca_system_score_codex":0.00003182888,"about_ca_system_score_gemma":0.00010147612,"threshold_uncertainty_score":0.8519143},"labels":[],"label_agreement":null},{"id":"W3016350258","doi":"10.1016/j.bmc.2020.115491","title":"Synthesis and cytotoxic effects of 2-thio-3,4-dihydroquinazoline derivatives as novel T-type calcium channel blockers","year":2020,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"National Research Foundation of Korea; Canadian Institutes of Health Research; Alberta Innovates; ASCRS Research Foundation; Health Research","keywords":"Chemistry; Moiety; Pharmacophore; Guanidine; Thio-; Calcium channel; Stereochemistry; Cytotoxic T cell; Biological activity; Combinatorial chemistry; Cell culture; Calcium; In vitro; Biochemistry; Organic chemistry","score_opus":0.01890192565335005,"score_gpt":0.24512398771754423,"score_spread":0.22622206206419418,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016350258","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931594,0.0013800499,0.0002008247,0.0029921108,0.00003566825,0.00013797972,0.00004186364,0.00013165707,0.0019204534],"genre_scores_gemma":[0.9983346,0.00021805207,0.0002539999,0.00027950507,0.0005543873,0.000046189136,0.00002305182,0.00006293073,0.00022730033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99807185,0.000012607662,0.0004953163,0.0006186564,0.0004049791,0.0003965799],"domain_scores_gemma":[0.9982501,0.0004572597,0.0002905346,0.00043281884,0.00011434816,0.0004549083],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001103578,0.00038902753,0.000600113,0.000025848562,0.00012144709,0.000017245557,0.00040835052,0.00029111886,0.0009935899],"category_scores_gemma":[0.0014467947,0.0003646789,0.00010453383,0.00034494814,0.00036815216,0.00005363484,0.00017247091,0.00033961315,0.00002884678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007975184,0.00018343293,0.00014081135,0.0018229587,0.000119213415,0.00001661377,0.00049982284,4.3974032e-7,0.9962432,0.000034258912,0.00038741226,0.00047210787],"study_design_scores_gemma":[0.0006743828,0.000056265744,0.0001857166,0.00036898788,0.00021312594,0.00006714349,0.0007749401,0.00023289732,0.995752,0.000039874853,0.0012925132,0.00034219908],"about_ca_topic_score_codex":0.000036813697,"about_ca_topic_score_gemma":4.3962112e-7,"teacher_disagreement_score":0.005175191,"about_ca_system_score_codex":0.00005429975,"about_ca_system_score_gemma":0.00016998913,"threshold_uncertainty_score":0.99991965},"labels":[],"label_agreement":null},{"id":"W3060446438","doi":"10.1007/s00432-020-03357-w","title":"Correction to: Afatinib is active in osteosarcoma cell lines","year":2020,"lang":"en","type":"erratum","venue":"Journal of Cancer Research and Clinical Oncology","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Afatinib; Osteosarcoma; Hematology; Medicine; Internal medicine; Oncology; Cancer research; Computer science; Cancer","score_opus":0.13942057777455868,"score_gpt":0.5180338997613347,"score_spread":0.37861332198677605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3060446438","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.293866,0.018512493,0.000033958288,0.1798018,0.04714266,0.001093753,0.00043716346,0.00004508969,0.45906705],"genre_scores_gemma":[0.22335446,0.21740586,0.000872123,0.004398835,0.064440005,0.0004482758,0.0000798719,0.00024180832,0.48875877],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99678504,0.00028133113,0.0014460569,0.00042815664,0.00062507374,0.00043436053],"domain_scores_gemma":[0.9943426,0.0032141057,0.0008371885,0.00022509866,0.0007975124,0.00058344606],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0013883817,0.00020050033,0.0010853078,0.00021974345,0.00009751328,0.000046858837,0.0005152095,0.00085283094,0.0013444318],"category_scores_gemma":[0.0018029726,0.00016647324,0.00026430984,0.00036793205,0.000268973,0.00006553083,0.00022706648,0.0062163724,0.00003880169],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011995904,0.0005671507,0.0007965482,0.000103341954,0.0000881804,0.000074930955,0.00017103448,8.4144364e-7,0.0009093843,0.0000053646704,0.82662016,0.16946344],"study_design_scores_gemma":[0.0010840563,0.0020212021,0.0023074364,0.0005029357,0.00005751205,0.000016949489,0.00057892024,0.00006381757,0.0031664353,0.00031965625,0.98972404,0.00015701666],"about_ca_topic_score_codex":0.00035963554,"about_ca_topic_score_gemma":0.0016189084,"teacher_disagreement_score":0.19889337,"about_ca_system_score_codex":0.00044530226,"about_ca_system_score_gemma":0.0031642318,"threshold_uncertainty_score":0.99956846},"labels":[],"label_agreement":null},{"id":"W3081503810","doi":"10.1016/j.jep.2020.113292","title":"Change in the active component of processed Tetradium ruticarpum extracts leads to improvement in efficacy and toxicity attenuation","year":2020,"lang":"en","type":"article","venue":"Journal of Ethnopharmacology","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"China Scholarship Council; Chinese Medicine Research Program of Zhejiang Province; National Natural Science Foundation of China","keywords":"Toxicity; Acute toxicity; Chemistry; Ethanol; Analgesic; Chromatography; Pharmacology; Traditional medicine; Food science; Medicine; Biochemistry; Organic chemistry","score_opus":0.06302133270297972,"score_gpt":0.34681828490260014,"score_spread":0.2837969521996204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3081503810","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9784421,0.000110448294,0.00002004572,0.020973776,0.0000336528,0.00022538101,0.000007049547,0.0000027162394,0.00018487955],"genre_scores_gemma":[0.99818945,0.00007030283,0.00008840769,0.0014199924,0.00018211799,0.000040288083,9.1584286e-7,0.000006444015,0.0000021023639],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909693,0.000047692698,0.0004299775,0.0001211062,0.00016051307,0.0001437894],"domain_scores_gemma":[0.99914664,0.00033920183,0.0002964782,0.000061767656,0.00007525914,0.000080663856],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029979734,0.00008863487,0.0002392058,0.000073036965,0.00002321179,0.000008044768,0.00020333225,0.00006536844,0.00008354912],"category_scores_gemma":[0.00012822551,0.00006744411,0.000032763324,0.00019482727,0.000046012647,0.000083881205,0.000033757617,0.00033756468,0.0000014475949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026513127,0.00043913993,0.00081036345,0.000063412714,0.00001922216,0.000014424127,0.004810402,0.000043341228,0.98464143,0.000023132045,0.0000913352,0.0087786885],"study_design_scores_gemma":[0.0013242322,0.00024852788,0.04684214,0.000050148985,0.00005477004,0.0000046631953,0.0007493081,0.0003638129,0.9498374,0.000030393048,0.00041765737,0.00007695369],"about_ca_topic_score_codex":0.00001708336,"about_ca_topic_score_gemma":0.00001189201,"teacher_disagreement_score":0.046031777,"about_ca_system_score_codex":0.000054436245,"about_ca_system_score_gemma":0.000047725538,"threshold_uncertainty_score":0.27502912},"labels":[],"label_agreement":null},{"id":"W3108913263","doi":"10.1039/d0nj03800h","title":"Investigation of biological activity of 2,3-disubstituted quinazolin-4(1<i>H</i>)-ones against <i>Mycobacterium tuberculosis</i> and DNA <i>via</i> docking, spectroscopy and DFT studies","year":2020,"lang":"en","type":"article","venue":"New Journal of Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Horizon College and Seminary","funders":"King Saud University","keywords":"Chemistry; Mycobacterium tuberculosis; Docking (animal); Stereochemistry; DNA; Combinatorial chemistry; Computational chemistry; Tuberculosis; Biochemistry","score_opus":0.03573038592697136,"score_gpt":0.26393166845226584,"score_spread":0.22820128252529448,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3108913263","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955361,0.0024232115,0.00007747368,0.0012856203,0.000024138551,0.000045451194,0.000031971078,0.000017058559,0.0005590018],"genre_scores_gemma":[0.99584556,0.0028680621,0.0007932166,0.000089901776,0.0003704634,0.0000026858688,0.0000063096486,0.000014782656,0.000009047066],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998661,0.000022347891,0.0006573721,0.00024942175,0.00023381125,0.00017605096],"domain_scores_gemma":[0.9982782,0.00017910154,0.00090067595,0.00017621272,0.00020254067,0.00026325768],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015956283,0.00022916378,0.000649182,0.00002158852,0.000061353945,0.000019237612,0.00018517704,0.00016528564,0.000042305674],"category_scores_gemma":[0.00021932443,0.00019261966,0.0001287035,0.00013816242,0.00038443517,0.00014357014,0.00008775049,0.00028922374,4.1997623e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013145302,0.000050156523,0.008301635,0.0006365841,0.00015487071,0.000004367631,0.000377452,0.000005257575,0.98895067,0.000009991894,0.0002845094,0.0010930608],"study_design_scores_gemma":[0.00066105986,0.000046881843,0.0016127359,0.00024456708,0.00011295375,0.000058162103,0.0002418752,0.000025079951,0.9961141,0.00031340623,0.00040611366,0.0001631062],"about_ca_topic_score_codex":0.0000070252704,"about_ca_topic_score_gemma":8.5686213e-7,"teacher_disagreement_score":0.007163397,"about_ca_system_score_codex":0.000029621415,"about_ca_system_score_gemma":0.000110682435,"threshold_uncertainty_score":0.78548014},"labels":[],"label_agreement":null},{"id":"W3133250232","doi":"10.1007/s13738-021-02199-8","title":"Synthesis, characterization, in vitro biological and molecular docking evaluation of N,N'-(ethane-1,2-diyl)bis(benzamides)","year":2021,"lang":"en","type":"article","venue":"Journal of the Iranian Chemical Society","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Laurentian University; Canadian Standards Association","funders":"","keywords":"Hemolysis; Amide; Chemistry; In vitro; Docking (animal); Stereochemistry; Nuclear chemistry; Organic chemistry; Biochemistry; Biology","score_opus":0.024497081642495817,"score_gpt":0.2632877222428465,"score_spread":0.2387906406003507,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133250232","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974276,0.00042462783,0.0000804836,0.0017026429,0.000025736896,0.0000484578,0.000024237308,0.0000037117281,0.00026253238],"genre_scores_gemma":[0.9988662,0.00015259384,0.000731986,0.00011224415,0.000103901526,0.0000071264126,0.000006890868,0.000010844812,0.000008216272],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99858606,0.00009045583,0.0005928977,0.00016116197,0.00042254452,0.00014687664],"domain_scores_gemma":[0.9987088,0.0002475986,0.00048319748,0.00021180259,0.00028988213,0.000058741],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00080530916,0.000116307965,0.0002988091,0.000015107229,0.000043810654,0.000022675298,0.00022963372,0.00017044978,0.00021258733],"category_scores_gemma":[0.0008430914,0.00008345009,0.00029825867,0.00018886794,0.00010364645,0.00005989601,0.00009016335,0.00028280684,3.185375e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018931,0.00012144926,0.0010090541,0.00003650129,0.00005023674,0.000001529303,0.00018605273,0.000018172785,0.9943593,0.000020145219,0.000017018221,0.0041616242],"study_design_scores_gemma":[0.0004065417,0.00000230936,0.0020224617,0.00013976426,0.000105184285,0.000048938782,0.00023241485,0.0009177002,0.9947707,0.00046462766,0.00079802517,0.00009131367],"about_ca_topic_score_codex":0.0000014853217,"about_ca_topic_score_gemma":2.2594213e-7,"teacher_disagreement_score":0.0040703104,"about_ca_system_score_codex":0.00010581589,"about_ca_system_score_gemma":0.00013423472,"threshold_uncertainty_score":0.34029958},"labels":[],"label_agreement":null},{"id":"W3157905541","doi":"10.1039/d1ce00337b","title":"Desolvation of dasatinib methanolate: an improved anhydrous polymorph","year":2021,"lang":"en","type":"article","venue":"CrystEngComm","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"Anhydrous; Dasatinib; Methanol; Transformation (genetics); Particle size; Particle (ecology); Chemistry; Materials science; Chemical engineering; Crystallography; Organic chemistry; Physical chemistry; Biology; Receptor; Biochemistry; Engineering","score_opus":0.020478293565508805,"score_gpt":0.26289283176591616,"score_spread":0.24241453820040734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3157905541","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9817437,0.00030903073,0.0011000672,0.00020938503,0.00003696815,0.000055673772,0.000049226746,0.000087741726,0.016408226],"genre_scores_gemma":[0.99414337,0.00001758273,0.004517067,0.000053636053,0.000117305004,0.000038858303,0.000117488235,0.00002751344,0.0009671947],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903065,0.000035436136,0.00034968017,0.00027070532,0.00012920218,0.00018431759],"domain_scores_gemma":[0.9987253,0.00013003858,0.00017087035,0.00073744537,0.0001514058,0.00008495805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013562753,0.00012902665,0.00023813528,0.000029908751,0.000090481095,0.000028489674,0.00020868864,0.00012167967,0.0007980646],"category_scores_gemma":[0.00013020303,0.00013110774,0.000090533285,0.00017105731,0.000045362416,0.0001054804,0.00006002013,0.00012424418,0.000014101236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007703116,0.00019156616,0.00065528054,0.00006012247,0.00002695574,0.000002736698,0.00022883028,0.00000573318,0.98585635,0.0010228724,0.000053515545,0.011888319],"study_design_scores_gemma":[0.00038151135,0.000018954315,0.0007563067,0.000050738414,0.00005182774,0.00002204827,0.00073179964,0.0048662773,0.98881227,0.0005789832,0.003537418,0.00019187556],"about_ca_topic_score_codex":0.000079708545,"about_ca_topic_score_gemma":0.000035692916,"teacher_disagreement_score":0.01544103,"about_ca_system_score_codex":0.000027584661,"about_ca_system_score_gemma":0.000079429745,"threshold_uncertainty_score":0.8738248},"labels":[],"label_agreement":null},{"id":"W3182272865","doi":"10.5267/j.ccl.2021.4.005","title":"Synthesis and biological evaluation of some new 2-pyridylquinazoline derivatives","year":2021,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Antimicrobial; Halogenation; Benzoic acid; Quinazoline; Bacteria; Combinatorial chemistry; Antibacterial activity; Stereochemistry; Organic chemistry","score_opus":0.06335190914666505,"score_gpt":0.3056267003107948,"score_spread":0.24227479116412975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3182272865","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941106,0.0029593564,0.00011576006,0.002061446,0.00003302199,0.000043902666,0.00004384497,0.000037325193,0.0005947492],"genre_scores_gemma":[0.9987427,0.00040390194,0.00030453203,0.000027451884,0.00035142488,0.000057642013,0.00008076867,0.000013590621,0.00001796355],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987846,0.000026494994,0.00030462755,0.00039612124,0.00029250435,0.00019567853],"domain_scores_gemma":[0.99906677,0.00018769117,0.00015975545,0.00035612713,0.000115139424,0.00011450489],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00017308067,0.00017605598,0.00024869264,0.000013356776,0.000062176376,0.000022723638,0.00014839947,0.00008410036,0.0019597104],"category_scores_gemma":[0.0005249877,0.00016804635,0.00009334859,0.00009963247,0.00014827709,0.000064400825,0.000088765235,0.00014440242,0.0000064941432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005964922,0.00011405813,0.0010434699,0.00015728439,0.00003247351,9.616106e-7,0.000044111588,0.000011327975,0.9578221,0.00009130112,0.0003754363,0.040301543],"study_design_scores_gemma":[0.00030523265,4.7652784e-7,0.0011325222,0.00012308857,0.000097381744,0.000010102535,0.0000945198,0.0002214872,0.9957157,0.0003822118,0.0017343749,0.0001829077],"about_ca_topic_score_codex":0.000002808479,"about_ca_topic_score_gemma":1.8002432e-7,"teacher_disagreement_score":0.040118635,"about_ca_system_score_codex":0.000049650032,"about_ca_system_score_gemma":0.00011706108,"threshold_uncertainty_score":0.9989526},"labels":[],"label_agreement":null},{"id":"W3198941517","doi":"10.26434/chemrxiv.13484763.v1","title":"Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes","year":2020,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium","funders":"National Cancer Institute; National Institutes of Health; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Chemistry; Biochemistry; Kinase; Protein kinase A; Serine; Enzyme; Biophysics; Biology","score_opus":0.03693349515281124,"score_gpt":0.26468536647783353,"score_spread":0.22775187132502228,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198941517","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98434234,0.0013580791,0.0008409472,0.003904761,0.00043782327,0.0010279217,0.00011455258,0.00077173917,0.0072018276],"genre_scores_gemma":[0.99052316,0.000105690604,0.0011638034,0.00020104482,0.0023451594,0.0012904002,0.0003870702,0.00024052874,0.0037431456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9948492,0.00004879699,0.0011770434,0.0021172725,0.00091950997,0.00088818045],"domain_scores_gemma":[0.99620384,0.00009254339,0.0007752201,0.0020698393,0.0002794149,0.00057916885],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003315819,0.0010824425,0.0010904585,0.00016093458,0.00038673967,0.0005149396,0.0013490865,0.0010742445,0.001231991],"category_scores_gemma":[0.00031346077,0.0011291197,0.0007502681,0.00024956753,0.00024118462,0.00015328653,0.0020624734,0.0016546812,0.000624663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005756751,0.00051611615,0.00007382373,0.00241907,0.00024380996,0.0001160925,0.00032947358,0.00009120318,0.9899559,0.00030893835,0.0022492793,0.0036387148],"study_design_scores_gemma":[0.00057710474,0.000012441185,0.00015350903,0.001171891,0.00022579628,0.000009853936,0.00029254184,0.00079988857,0.98861957,0.0019665516,0.004935167,0.0012357105],"about_ca_topic_score_codex":0.00023884777,"about_ca_topic_score_gemma":0.000015991482,"teacher_disagreement_score":0.0061808084,"about_ca_system_score_codex":0.00049010484,"about_ca_system_score_gemma":0.00035970274,"threshold_uncertainty_score":0.999681},"labels":[],"label_agreement":null},{"id":"W3202531487","doi":"10.3390/molecules26195911","title":"Synthesis and Evaluation of Novel 1,2,6-Thiadiazinone Kinase Inhibitors as Potent Inhibitors of Solid Tumors","year":2021,"lang":"en","type":"article","venue":"Molecules","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Division of Chemistry; University of North Carolina at Chapel Hill; National Institutes of Health; Common Fund; Biocenter Finland; Ministero dello Sviluppo Economico; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; University of Cyprus; Ontario Ministry of Economic Development and Innovation; European Federation of Pharmaceutical Industries and Associations; Wellcome Trust; Novartis Pharma; China Scholarship Council; National Institute of Diabetes and Digestive and Kidney Diseases; A.G. Leventis Foundation; Research Promotion Foundation; Pfizer; National Science Foundation","keywords":"Prostate cancer; Cancer research; Kinase; Cell culture; Fibroblast; Chemistry; Medicine; Cancer; Internal medicine; Biology; Biochemistry","score_opus":0.021211720711257136,"score_gpt":0.27541122629216835,"score_spread":0.2541995055809112,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3202531487","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99308085,0.00096282846,0.00009670266,0.00031930968,0.000027289063,0.00009371865,0.00011620338,0.00002053895,0.005282575],"genre_scores_gemma":[0.99872106,0.00006246112,0.0009291886,0.000020886573,0.000064274944,0.00007772305,0.000020596935,0.000025427782,0.00007837858],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984742,0.000042043135,0.00048470564,0.0003194042,0.0005073585,0.00017229326],"domain_scores_gemma":[0.99873805,0.0001453453,0.00026600927,0.00039143622,0.00036985305,0.000089322886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031639537,0.00016267823,0.0003118881,0.00006903212,0.00006379224,0.000013306065,0.00010453685,0.000107462794,0.000265289],"category_scores_gemma":[0.00055146223,0.00016663778,0.00011817009,0.00017847221,0.0001406414,0.000047644367,0.000090499496,0.00008896658,0.0000061012306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009467203,0.00039120764,0.0003134611,0.0001388161,0.000048451115,0.0000042023985,0.00014492725,0.00017816029,0.9770826,0.0008322878,0.000097879565,0.02075853],"study_design_scores_gemma":[0.00033901958,0.000012092072,0.0012093376,0.00026440175,0.00017901813,0.000016556329,0.0005948007,0.001468732,0.99520165,0.00037266104,0.00018471143,0.0001570424],"about_ca_topic_score_codex":0.00009728736,"about_ca_topic_score_gemma":0.0000138752175,"teacher_disagreement_score":0.020601489,"about_ca_system_score_codex":0.000041405165,"about_ca_system_score_gemma":0.00019726343,"threshold_uncertainty_score":0.67952913},"labels":[],"label_agreement":null},{"id":"W3204665343","doi":"10.2174/1570178618666211001115131","title":"Design, Synthesis and In vitroCytotoxic Evaluation of Novel Hybrids ofArtemisinin and Quinazolinone","year":2021,"lang":"en","type":"article","venue":"Letters in Organic Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of the Fraser Valley","funders":"Trường Đại học Bách Khoa Hà Nội","keywords":"Cytotoxicity; Artemisinin; Quinazolinone; Cytotoxic T cell; Chemistry; Cell culture; Cancer cell; Cancer cell lines; Cancer; Cancer research; In vitro; Pharmacology; Biochemistry; Stereochemistry; Immunology; Biology; Plasmodium falciparum; Genetics; Malaria","score_opus":0.026575424677374986,"score_gpt":0.25274821271869563,"score_spread":0.22617278804132065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204665343","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99720967,0.0005407402,0.00051114976,0.00090979,0.0000082081815,0.00007863608,0.000015903299,0.000017389926,0.0007085159],"genre_scores_gemma":[0.998209,0.00011184329,0.0013698085,0.000096702526,0.000044429362,0.00007653241,0.000011663424,0.000027316364,0.000052677988],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99857086,0.00003366842,0.00042566122,0.00045481033,0.00028864594,0.00022637082],"domain_scores_gemma":[0.99902654,0.0003365537,0.00013395127,0.00038288118,0.000059603706,0.000060494982],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00049689406,0.00018327215,0.0003203687,0.000034723053,0.0000343575,0.000023019407,0.00012662668,0.0001400872,0.0015135908],"category_scores_gemma":[0.00039725003,0.00021471392,0.00003122359,0.00022349638,0.00010944211,0.000055710403,0.00009342231,0.00021047215,0.0000013787356],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017527771,0.00019422901,0.0017280016,0.00021720836,0.000017634846,0.000009378413,0.00012321532,0.00004271171,0.9941327,0.0000028454801,0.00002055144,0.0034939796],"study_design_scores_gemma":[0.0010039194,0.0000015139642,0.0018953928,0.00020223392,0.000059296257,0.000081030485,0.0002606906,0.0029740224,0.99324006,0.00005145316,0.000029376477,0.0002009861],"about_ca_topic_score_codex":0.000012933932,"about_ca_topic_score_gemma":0.0000070038463,"teacher_disagreement_score":0.0032929934,"about_ca_system_score_codex":0.00014883683,"about_ca_system_score_gemma":0.00012062153,"threshold_uncertainty_score":0.9993992},"labels":[],"label_agreement":null},{"id":"W4200313047","doi":"10.1002/cmdc.202100733","title":"Efficient Synthesis of Benzothiazinone Analogues with Activity against Intracellular <i>Mycobacterium tuberculosis</i>","year":2021,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Antimycobacterial; Quinazolinone; Mycobacterium tuberculosis; Chemistry; Combinatorial chemistry; Thiourea; Broth microdilution; Resazurin; Stereochemistry; In vitro; Tuberculosis; Biochemistry; Minimum inhibitory concentration; Organic chemistry; Medicine","score_opus":0.009205164694648238,"score_gpt":0.2097157941187638,"score_spread":0.20051062942411554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200313047","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9727647,0.00034849605,0.00018502442,0.0005203959,0.00002499337,0.00006431134,0.00010984358,0.00008923759,0.025893003],"genre_scores_gemma":[0.99814004,0.000101628175,0.0011154131,0.000041936106,0.00013683105,0.00010326587,0.000059174297,0.000047778743,0.00025394637],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99841136,0.000022886295,0.00033255274,0.0005283554,0.00033474318,0.00037010052],"domain_scores_gemma":[0.99828535,0.00026346644,0.00022215195,0.0008550186,0.00021343815,0.00016059517],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013505816,0.0002825554,0.0004815202,0.00003903266,0.000104610335,0.00003199058,0.00023513139,0.0001793548,0.0005453731],"category_scores_gemma":[0.00013095763,0.0002550932,0.00017839277,0.00032403955,0.00019592047,0.00003952315,0.00010591975,0.00023201255,0.000033938984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003345515,0.0007024772,0.0005969631,0.0003470052,0.00013782136,0.000023003893,0.00010405878,0.000084617204,0.98967355,0.0001555933,0.00012594018,0.008015538],"study_design_scores_gemma":[0.00023505384,0.000005717236,0.00055915664,0.0001802475,0.00013567088,0.000021157535,0.0002531817,0.00054716144,0.9962756,0.000017106042,0.0014692148,0.00030075264],"about_ca_topic_score_codex":0.000018536963,"about_ca_topic_score_gemma":0.000011554217,"teacher_disagreement_score":0.025639055,"about_ca_system_score_codex":0.00008275212,"about_ca_system_score_gemma":0.00014635957,"threshold_uncertainty_score":0.9999901},"labels":[],"label_agreement":null},{"id":"W4220934739","doi":"10.3389/fimmu.2022.859400","title":"Epigenetic Regulation in the Pathogenesis of Rheumatoid Arthritis","year":2022,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Jiangxi University of Traditional Chinese Medicine; Chengdu University of Traditional Chinese Medicine; Chengdu University; Universidade de Macau; Fundo para o Desenvolvimento das Ciências e da Tecnologia; China Postdoctoral Science Foundation; Ningbo University; National Natural Science Foundation of China","keywords":"Epigenetics; Pathogenesis; DNA methylation; Rheumatoid arthritis; Histone; Medicine; Mechanism (biology); Immunology; Epigenesis; Bioinformatics; Disease; Biology; Genetics; Gene; Gene expression; Pathology","score_opus":0.020801406131738545,"score_gpt":0.2566763542473582,"score_spread":0.23587494811561965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220934739","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002165728,0.9974078,0.00013295382,0.000026403435,0.00020497268,0.00025820988,0.00007083153,0.000012440377,0.0016698359],"genre_scores_gemma":[0.00039915362,0.9976768,0.00054643827,0.000005321968,0.000022835738,0.0010255,0.00020915866,0.000034760826,0.00008001531],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99812853,0.00029085402,0.0008633172,0.00033496637,0.00013340276,0.0002489111],"domain_scores_gemma":[0.9984813,0.00026081334,0.00045375674,0.00078283675,0.000010791281,0.000010518485],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00035036344,0.00023013019,0.0011320219,0.0002626392,0.0000659597,0.000007816397,0.00070906663,0.00031964784,0.0009167498],"category_scores_gemma":[0.00008251423,0.00019852775,0.0002531589,0.00045761582,0.00014609926,0.000019632762,0.00010479279,0.00042873027,0.000008224652],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000038630105,0.00009245457,0.000058356007,0.00064980646,0.00004985765,0.000004455712,0.00013652178,0.0000028970178,0.00005175219,0.0003215497,0.00037730523,0.9982512],"study_design_scores_gemma":[0.00014291653,0.00000933463,0.00017961478,0.0012173391,0.00002590258,0.000032956632,0.0003912821,0.000005794361,0.00003642933,0.0006610657,0.9971246,0.00017273096],"about_ca_topic_score_codex":0.000060073045,"about_ca_topic_score_gemma":0.000020393933,"teacher_disagreement_score":0.99807847,"about_ca_system_score_codex":0.00015274098,"about_ca_system_score_gemma":0.00014277996,"threshold_uncertainty_score":0.99999654},"labels":[],"label_agreement":null},{"id":"W4248158530","doi":"10.26434/chemrxiv.13484763","title":"Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes","year":2020,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium","funders":"National Cancer Institute; National Institutes of Health; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Chemistry; Kinase; Biochemistry; Protein kinase A; Serine; Enzyme","score_opus":0.03693349515281124,"score_gpt":0.26468536647783353,"score_spread":0.22775187132502228,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4248158530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98434234,0.0013580791,0.0008409472,0.003904761,0.00043782327,0.0010279217,0.00011455258,0.00077173917,0.0072018276],"genre_scores_gemma":[0.99052316,0.000105690604,0.0011638034,0.00020104482,0.0023451594,0.0012904002,0.0003870702,0.00024052874,0.0037431456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9948492,0.00004879699,0.0011770434,0.0021172725,0.00091950997,0.00088818045],"domain_scores_gemma":[0.99620384,0.00009254339,0.0007752201,0.0020698393,0.0002794149,0.00057916885],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003315819,0.0010824425,0.0010904585,0.00016093458,0.00038673967,0.0005149396,0.0013490865,0.0010742445,0.001231991],"category_scores_gemma":[0.00031346077,0.0011291197,0.0007502681,0.00024956753,0.00024118462,0.00015328653,0.0020624734,0.0016546812,0.000624663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005756751,0.00051611615,0.00007382373,0.00241907,0.00024380996,0.0001160925,0.00032947358,0.00009120318,0.9899559,0.00030893835,0.0022492793,0.0036387148],"study_design_scores_gemma":[0.00057710474,0.000012441185,0.00015350903,0.001171891,0.00022579628,0.000009853936,0.00029254184,0.00079988857,0.98861957,0.0019665516,0.004935167,0.0012357105],"about_ca_topic_score_codex":0.00023884777,"about_ca_topic_score_gemma":0.000015991482,"teacher_disagreement_score":0.0061808084,"about_ca_system_score_codex":0.00049010484,"about_ca_system_score_gemma":0.00035970274,"threshold_uncertainty_score":0.999681},"labels":[],"label_agreement":null},{"id":"W4293056349","doi":"10.1021/acs.jafc.2c03122","title":"Synergistic Inhibitory Effects of Selected Amino Acids on the Formation of 2-Amino-1-methyl-6-phenylimidazo[4,5-<i>b</i>]pyridine (PhIP) in both Benzaldehyde– and Phenylacetaldehyde–Creatinine Model Systems","year":2022,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Natural Science Foundation of China","keywords":"Phenylacetaldehyde; Chemistry; Phenylalanine; Benzaldehyde; Amino acid; Creatinine; Organic chemistry; Medicinal chemistry; Biochemistry","score_opus":0.008100586447957173,"score_gpt":0.1875393420133103,"score_spread":0.17943875556535313,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293056349","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99729574,0.0014739725,0.00001692321,0.00015575557,0.000027500166,0.00012502776,0.000066903725,0.000010568925,0.0008276133],"genre_scores_gemma":[0.99939376,0.00018474947,0.000049051858,0.000009350492,0.00013716119,0.00004583877,0.000024984061,0.000012398779,0.0001427308],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99835306,0.000047225385,0.0008023326,0.00018140748,0.00041708106,0.0001988973],"domain_scores_gemma":[0.9982027,0.0003745587,0.0009792596,0.00016890293,0.00018158027,0.000093045535],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024794138,0.00023261023,0.0005018443,0.0000366704,0.00015559302,0.000026515389,0.00022452151,0.000103665734,0.000029810672],"category_scores_gemma":[0.00013212292,0.00014263438,0.00010894022,0.00026995727,0.000098753,0.000113714974,0.00010256197,0.00045901872,1.4926819e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006995823,0.00026122917,0.00019091064,0.0010666568,0.00007669601,0.0000018817134,0.00044790652,0.0030537206,0.99429846,0.00011636566,0.00023220014,0.00018402298],"study_design_scores_gemma":[0.0010546179,0.0002600335,0.0034299917,0.0004504818,0.00015230184,0.00014082316,0.0025312998,0.004303241,0.98734254,0.00007195486,0.000049689166,0.00021305119],"about_ca_topic_score_codex":0.000009162039,"about_ca_topic_score_gemma":0.000001241305,"teacher_disagreement_score":0.0069559375,"about_ca_system_score_codex":0.00008707702,"about_ca_system_score_gemma":0.000044907418,"threshold_uncertainty_score":0.58164614},"labels":[],"label_agreement":null},{"id":"W4298296759","doi":"10.17615/66q8-7d37","title":"Optimization of Cellular Activity of G9a Inhibitors 7-Aminoalkoxy-quinazolines","year":2020,"lang":"en","type":"article","venue":"Figshare","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; University of North Carolina at Chapel Hill; Ontario Genomics; National Institutes of Health; Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Stiftelsen för Strategisk Forskning; Ontario Genomics Institute; Genome Canada; GlaxoSmithKline; Ontario Innovation Trust; Wellcome Trust","keywords":"Computational biology; Biology","score_opus":0.036568622903361714,"score_gpt":0.23704385857215005,"score_spread":0.20047523566878833,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4298296759","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5232363,0.0008413593,0.0010465457,0.001552841,0.00005140581,0.00059968815,0.4317439,0.00039976017,0.04052822],"genre_scores_gemma":[0.9900292,0.0000041302233,0.00035374716,0.000017418695,0.00015790845,0.000049126862,0.00930185,0.000019001987,0.00006760047],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99931276,0.000008473096,0.0002319112,0.00018605402,0.00015345965,0.00010733697],"domain_scores_gemma":[0.9992586,0.00007335723,0.00025347795,0.00022474177,0.000121739766,0.00006809168],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000015165209,0.00010775139,0.00020114503,0.000019910509,0.000030557054,0.000007248066,0.00017880774,0.00009539818,0.08759098],"category_scores_gemma":[0.0003530898,0.00010899885,0.00010062707,0.00016374075,0.000011199866,0.000069366,0.000078086734,0.00008025847,0.00008158053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025979987,0.0002029502,0.000117100666,0.0014962406,0.000033162512,0.0000017850244,0.00021920927,0.005747297,0.9582369,0.00003566833,0.02984503,0.004038705],"study_design_scores_gemma":[0.0001269846,0.000012275758,0.000070946095,0.00027429828,0.000014143142,3.234193e-7,0.000038351933,0.009813141,0.9814188,0.000005013324,0.008121713,0.00010402121],"about_ca_topic_score_codex":0.0000058112723,"about_ca_topic_score_gemma":4.925383e-7,"teacher_disagreement_score":0.4667929,"about_ca_system_score_codex":0.000010149756,"about_ca_system_score_gemma":0.00003895875,"threshold_uncertainty_score":0.9132431},"labels":[],"label_agreement":null},{"id":"W4307460411","doi":"10.1016/s0959-8049(22)00845-0","title":"Superior efficacy of a dual EGFR-DNA targeting combi-molecule “ZR2002” in comparison with its analogues 6-mono-alkylamino- and 6,6-dialkylaminoquinazoline in a human osteosarcoma xenograft model","year":2022,"lang":"en","type":"article","venue":"European Journal of Cancer","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"In vivo; Prodrug; Chemistry; Quinazoline; Pharmacology; Western blot; Epidermal growth factor receptor; Pharmacokinetics; Metabolite; Phosphorylation; Mechanism of action; In vitro; DNA damage; Cancer research; DNA; Receptor; Biochemistry; Biology; Stereochemistry","score_opus":0.02085764652218134,"score_gpt":0.27539861340429855,"score_spread":0.2545409668821172,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307460411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940947,0.0035558064,0.000043531563,0.00029164815,0.000020385603,0.00011250518,0.00005853195,0.000011896897,0.0018109563],"genre_scores_gemma":[0.99912184,0.00010476725,0.0004148537,0.00004240414,0.00010042125,0.000017333019,0.000015952539,0.000055323668,0.00012707479],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977426,0.00020761839,0.0010392286,0.0002708676,0.00040905798,0.00033063858],"domain_scores_gemma":[0.9988007,0.00008560166,0.00066745095,0.00020906416,0.00012276294,0.00011444844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074064144,0.000226141,0.000562871,0.00024279146,0.00014636588,0.000034515037,0.00034315424,0.00002602276,0.00020631777],"category_scores_gemma":[0.000040665636,0.00021150999,0.00009509902,0.0003151206,0.00011328772,0.000108561006,0.00017680648,0.00057529367,9.179376e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008920811,0.0018143234,0.07373559,0.00020633939,0.00015455339,0.00048494153,0.0070416047,0.033950195,0.8714674,0.0003777937,0.00040712088,0.0094680805],"study_design_scores_gemma":[0.037723195,0.0032456378,0.29425344,0.002454465,0.00067887525,0.00055388495,0.015915107,0.04527198,0.58299255,0.00013090468,0.013985074,0.0027949053],"about_ca_topic_score_codex":0.000058895937,"about_ca_topic_score_gemma":0.00012858622,"teacher_disagreement_score":0.28847483,"about_ca_system_score_codex":0.00012861371,"about_ca_system_score_gemma":0.0001185056,"threshold_uncertainty_score":0.8625127},"labels":[],"label_agreement":null},{"id":"W4309713572","doi":"10.1186/s13065-022-00893-z","title":"Synthesis, biological evaluation, and computational studies of some novel quinazoline derivatives as anticancer agents","year":2022,"lang":"en","type":"article","venue":"BMC Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"Shiraz Transplant Research Center, Shiraz University of Medical Sciences","keywords":"Quinazolinone; Chemistry; Combinatorial chemistry; Docking (animal); Quinazoline; Cytotoxicity; Selectivity; Cell culture; Cancer cell lines; MTT assay; Stereochemistry; Lipinski's rule of five; Biochemistry; Cell growth; Cancer cell; In vitro; Cancer; Biology; In silico","score_opus":0.10705880516365851,"score_gpt":0.3626342194377109,"score_spread":0.2555754142740524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309713572","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959494,0.0016697474,0.00007830095,0.00023386347,0.000016100514,0.00008904557,0.00016795659,0.000033603956,0.001761984],"genre_scores_gemma":[0.9976948,0.000121274155,0.0013288853,0.000048663216,0.00009971416,0.0004078542,0.00007892661,0.000013829383,0.00020603443],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987198,0.000024744219,0.00034339767,0.00035326864,0.0003985559,0.00016023286],"domain_scores_gemma":[0.9987771,0.0005653098,0.00022098824,0.00022018998,0.00016134915,0.000055099856],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00030525762,0.00015454697,0.00027203016,0.000016943715,0.00024662874,0.000010341604,0.0001919893,0.000053053398,0.002684949],"category_scores_gemma":[0.00063261535,0.00014753776,0.000068636735,0.00010284804,0.0002682831,0.000040890736,0.0002493432,0.0001211715,0.0000027081555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059023103,0.0004704135,0.00873173,0.00037834616,0.00018967291,9.708515e-7,0.0003023873,0.0014669803,0.9845422,0.0021548674,0.000341203,0.0013622103],"study_design_scores_gemma":[0.000963785,0.000018431543,0.008048811,0.00007538697,0.00013659136,0.000043266296,0.0043043615,0.00536882,0.96995366,0.008398281,0.0022950068,0.00039360413],"about_ca_topic_score_codex":0.000005810048,"about_ca_topic_score_gemma":3.434556e-7,"teacher_disagreement_score":0.01458854,"about_ca_system_score_codex":0.000093345865,"about_ca_system_score_gemma":0.00015048384,"threshold_uncertainty_score":0.99822676},"labels":[],"label_agreement":null},{"id":"W4311487729","doi":"10.1002/ejoc.202201098","title":"Visible‐Light‐Driven One‐Pot Synthesis of Benzimidazoles, Benzothiazoles, and Quinazolinones Catalyzed by Scalable and Reusable Ba‐Doped CoMoO<sub>4</sub> Nanoparticles Under Air Atmosphere","year":2022,"lang":"en","type":"article","venue":"European Journal of Organic Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"SRM Institute of Science and Technology","keywords":"Chemistry; Catalysis; Aryl; Combinatorial chemistry; Doping; Nanoparticle; Substrate (aquarium); Benzene; Reusability; Nanotechnology; Photochemistry; Materials science; Organic chemistry; Optoelectronics; Computer science","score_opus":0.007653401091925715,"score_gpt":0.18851180456833425,"score_spread":0.18085840347640852,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311487729","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927172,0.003029004,0.000028547733,0.00096676394,0.000028215754,0.00007680389,0.00014306704,0.000044870783,0.0029654945],"genre_scores_gemma":[0.99814713,0.00096514815,0.00032138568,0.000053538766,0.00014301903,0.000009214075,0.000022293361,0.000117212825,0.00022105109],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99735993,0.00013589814,0.0010781009,0.00046298542,0.0005403617,0.00042274653],"domain_scores_gemma":[0.99767536,0.00023440574,0.0009850563,0.00059105706,0.00017304515,0.0003410694],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006779883,0.00037121645,0.00067248003,0.000024558642,0.00045168665,0.00007275236,0.000659797,0.0000798152,0.001558633],"category_scores_gemma":[0.00013291274,0.00038404888,0.00014567826,0.00027946808,0.00022021262,0.0001727393,0.0005628628,0.0005719407,0.00001050687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010895116,0.0004830676,0.0006641867,0.00034714094,0.00020387987,0.00003902268,0.00018680347,0.00009902371,0.99347824,0.00002180612,0.0021892346,0.0021786725],"study_design_scores_gemma":[0.0010813758,0.000039513663,0.00052622677,0.00024327375,0.00027570457,0.0004073129,0.0015966209,0.000064095075,0.9923858,0.00006556954,0.002923809,0.00039067512],"about_ca_topic_score_codex":0.0000081005,"about_ca_topic_score_gemma":0.000003082584,"teacher_disagreement_score":0.005429905,"about_ca_system_score_codex":0.00013294889,"about_ca_system_score_gemma":0.00016692304,"threshold_uncertainty_score":0.9998611},"labels":[],"label_agreement":null},{"id":"W4313481612","doi":"10.1002/slct.202203618","title":"Acid‐Catalysed Cyclization of <i>o</i> ‐Aminobenzamide with <i>α</i> ‐Oxodithioesters: A Divergent and Regioselective Synthesis of Quinazolinones and 1,3‐Benzothiazinones","year":2023,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Regioselectivity; Acetic acid; Chemistry; Catalysis; Combinatorial chemistry; Generality; Medicinal chemistry; Stereochemistry; Organic chemistry","score_opus":0.00860499444330758,"score_gpt":0.21235109401494154,"score_spread":0.20374609957163395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313481612","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956124,0.0004541671,0.00010010963,0.00013642352,0.000008130033,0.00012564563,0.00008228544,0.00011387279,0.0033669935],"genre_scores_gemma":[0.9984563,0.0008417043,0.00021990856,0.000013005828,0.000051484698,0.00012414134,0.000053693442,0.000042002426,0.00019776361],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984906,0.000017094791,0.00041908567,0.0005023097,0.0002695558,0.000301359],"domain_scores_gemma":[0.9985672,0.00033582834,0.0003843693,0.00041499626,0.00018088387,0.00011671487],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001406076,0.00028243207,0.00048980716,0.00008754747,0.000119964556,0.00002208061,0.00019457712,0.00015877953,0.000035319303],"category_scores_gemma":[0.00018812515,0.00025321162,0.00007092755,0.0005503677,0.00033307058,0.00009838904,0.000099579374,0.00012371772,0.000002646093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000109363245,0.00010574802,0.010266463,0.0008438077,0.0001308766,0.0000035357414,0.00041821288,0.000011291098,0.98491836,0.00010596068,0.00013523978,0.0029511238],"study_design_scores_gemma":[0.00042307787,0.0000332762,0.0032150366,0.00024942416,0.00018308744,0.0000337303,0.0006901329,0.00017888613,0.9944187,0.0001520156,0.0001529025,0.00026974818],"about_ca_topic_score_codex":0.000055212957,"about_ca_topic_score_gemma":0.00001687868,"teacher_disagreement_score":0.009500305,"about_ca_system_score_codex":0.000027608225,"about_ca_system_score_gemma":0.00007974251,"threshold_uncertainty_score":0.999992},"labels":[],"label_agreement":null},{"id":"W4327622012","doi":"10.3390/cells12060914","title":"Molecular Analysis of the Superior Efficacy of a Dual Epidermal Growth Factor Receptor (EGFR)-DNA-Targeting Combi-Molecule in Comparison with Its Putative Prodrugs 6-Mono-Alkylamino- and 6,6-Dialkylaminoquinazoline in a Human Osteosarcoma Xenograft Model","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Fondation du cancer des Cèdres; McGill University Health Centre; McGill University","keywords":"In vivo; Quinazoline; Epidermal growth factor receptor; Chemistry; DNA; DNA damage; Western blot; Cancer research; Molecular biology; Pharmacology; Receptor; Biology; Biochemistry; Stereochemistry; Gene","score_opus":0.016344588603067745,"score_gpt":0.26459296042045094,"score_spread":0.24824837181738318,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4327622012","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986467,0.00015008017,0.000049685907,0.00017432834,0.000008512645,0.0004418926,0.00024372313,0.000036364498,0.00024873135],"genre_scores_gemma":[0.99929446,0.000017517545,0.0003078499,0.000014749662,0.000011758739,0.000101663296,0.00013623154,0.000043038104,0.0000727406],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976638,0.0001193862,0.0008812176,0.00053845573,0.00035136886,0.0004457838],"domain_scores_gemma":[0.9986317,0.00030873716,0.00041516716,0.00042268608,0.00013376535,0.000087922184],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002853737,0.00030697658,0.0008469688,0.00037373006,0.00009206128,0.000025469399,0.0003292121,0.00013820123,0.00004544314],"category_scores_gemma":[0.00009827157,0.00025181114,0.00018889848,0.0017011265,0.000243905,0.00007824083,0.00020133171,0.00028543963,0.0000030512613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006836324,0.0005328373,0.021142378,0.00020236318,0.00020096364,0.000007396942,0.0042669266,0.0077574668,0.96534723,0.00027017068,0.000013272321,0.00019064703],"study_design_scores_gemma":[0.0011876756,0.000048411042,0.022138618,0.00011346259,0.00023009045,6.042942e-7,0.001230383,0.04391046,0.9308469,0.000027213302,0.000006762574,0.00025940646],"about_ca_topic_score_codex":0.00016469155,"about_ca_topic_score_gemma":0.00009133587,"teacher_disagreement_score":0.036152992,"about_ca_system_score_codex":0.000060110408,"about_ca_system_score_gemma":0.00008016466,"threshold_uncertainty_score":0.9999934},"labels":[],"label_agreement":null},{"id":"W4327915230","doi":"10.1007/s11164-023-04998-5","title":"Synthesis of biologically active dihydroquinazolinone catalyzed by the micro–meso-composite of zeolite H-BEA","year":2023,"lang":"en","type":"article","venue":"Research on Chemical Intermediates","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Catalysis; Zeolite; Microporous material; Mesoporous material; Chemistry; Magic angle spinning; Sodalite; Bromide; Fourier transform infrared spectroscopy; Chemical engineering; Materials science; Organic chemistry; Nuclear magnetic resonance spectroscopy","score_opus":0.04774080971067572,"score_gpt":0.3573911452935184,"score_spread":0.30965033558284266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4327915230","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915082,0.00015063085,0.0000017753588,0.0013138542,0.000015566791,0.00017038349,0.0007890226,0.00007576995,0.005974817],"genre_scores_gemma":[0.99851435,0.0004245141,0.000039952956,0.000018590586,0.00011011871,0.0003088077,0.00018487619,0.00003301564,0.00036576152],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975633,0.00011800881,0.00056746457,0.00048890966,0.0006222303,0.0006400787],"domain_scores_gemma":[0.99256843,0.0060663726,0.00019959387,0.00072547555,0.00027406772,0.0001660633],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007129542,0.00022613259,0.00047821784,0.00015301692,0.00011655818,0.00002562327,0.0011524324,0.0002397338,0.0005317019],"category_scores_gemma":[0.0013380725,0.00014878287,0.00024012968,0.00068442756,0.0011514475,0.00004415954,0.00046397193,0.00060977024,0.00021688019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022967486,0.00038735665,0.00030337714,0.00014810424,0.00010182981,0.000002863957,0.00015575727,0.0000010567197,0.9892637,0.0003330038,0.0031631205,0.0059101502],"study_design_scores_gemma":[0.00020089286,0.000032385695,0.00039982164,0.00019504999,0.000019484432,0.0000023197792,0.00035264244,0.00012241396,0.99659944,0.0007259392,0.0012048185,0.00014480746],"about_ca_topic_score_codex":0.00010078288,"about_ca_topic_score_gemma":0.0000013912558,"teacher_disagreement_score":0.0073357197,"about_ca_system_score_codex":0.00008613265,"about_ca_system_score_gemma":0.000058570928,"threshold_uncertainty_score":0.6067189},"labels":[],"label_agreement":null},{"id":"W4366089932","doi":"10.1007/s12039-023-02157-2","title":"Environmentally benign synthesis of quinazoline-based heterocyclic compounds over zeolite H-BEA catalyst with bimodal porosity","year":2023,"lang":"en","type":"article","venue":"Journal of Chemical Sciences","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Catalysis; Zeolite; Magic angle spinning; Chemistry; Nuclear chemistry; Thermogravimetric analysis; Ammonium bromide; Materials science; Organic chemistry; Nuclear magnetic resonance spectroscopy; Pulmonary surfactant","score_opus":0.013227736925093289,"score_gpt":0.24455841795965677,"score_spread":0.23133068103456347,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366089932","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99758154,0.00005426515,0.00003721067,0.0005812533,0.000018108483,0.000032610962,0.00003867214,0.000019771262,0.0016365385],"genre_scores_gemma":[0.99895006,0.000021109661,0.0008188241,0.000038733033,0.00011723256,0.000006991841,0.000005440828,0.000011290744,0.000030330957],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981176,0.000016928334,0.00054720754,0.00024159934,0.0007817569,0.00029489293],"domain_scores_gemma":[0.9985955,0.00039779206,0.0005678305,0.00022113022,0.000046579065,0.00017121178],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036886483,0.00016404943,0.0003762564,0.00010489854,0.000119809265,0.000044425855,0.0006223472,0.00008376283,0.0002273986],"category_scores_gemma":[0.000073676114,0.00011480618,0.00019062393,0.00040319472,0.0007124967,0.00016477196,0.000069514266,0.00016886977,0.000010289434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005936212,0.00022242856,0.01552345,0.000040492563,0.00002926577,0.000007990985,0.000038850318,0.00016480258,0.9829944,0.00005305402,0.00016961843,0.00069628755],"study_design_scores_gemma":[0.00030574395,0.00004364843,0.0050203283,0.00011819573,0.00006165395,0.000035763096,0.0001177219,0.00043124714,0.9930523,0.00018625667,0.0004754885,0.00015165715],"about_ca_topic_score_codex":0.000038798404,"about_ca_topic_score_gemma":0.0000033082229,"teacher_disagreement_score":0.010503123,"about_ca_system_score_codex":0.00007774449,"about_ca_system_score_gemma":0.000083972955,"threshold_uncertainty_score":0.46816602},"labels":[],"label_agreement":null},{"id":"W4385060516","doi":"10.7150/jca.86757","title":"Moxidectin induces Cytostatic Autophagic Cell Death of Glioma Cells through inhibiting the AKT/mTOR Signalling Pathway: Erratum","year":2023,"lang":"en","type":"erratum","venue":"Journal of Cancer","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Autophagy; PI3K/AKT/mTOR pathway; RPTOR; Protein kinase B; Moxidectin; Cancer research; Programmed cell death; Cell biology; Apoptosis; Chemistry; Biology; Signal transduction; Biochemistry; Ivermectin","score_opus":0.030860964156482446,"score_gpt":0.28896279618191256,"score_spread":0.25810183202543013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385060516","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91080207,0.021009224,0.0001850666,0.0011692322,0.009611252,0.00032516362,0.00050519424,0.00009408249,0.056298725],"genre_scores_gemma":[0.926919,0.0040040286,0.0007371464,0.00014847382,0.008059961,0.00009519251,0.000029071607,0.00027317295,0.059733972],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99658096,0.00007579969,0.0015629352,0.00035481094,0.00094790856,0.00047755978],"domain_scores_gemma":[0.99477106,0.0005820221,0.0036031466,0.00041048066,0.0005104913,0.00012281962],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005591471,0.00046934828,0.0009646295,0.00015905898,0.00024709146,0.00011938716,0.00083522755,0.000508756,0.0005929067],"category_scores_gemma":[0.00012074708,0.00033447464,0.00058582524,0.00042689196,0.00010912053,0.00016570333,0.00012582222,0.0020635528,0.000021471387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003495052,0.00013736243,0.000021124915,0.0010197976,0.00030954203,0.00009749975,0.0011917005,0.00047723722,0.8287008,0.000099017445,0.16665266,0.0012583283],"study_design_scores_gemma":[0.00038730455,0.00005256199,0.000033012915,0.002639288,0.00040692647,0.000035628236,0.0015978642,0.00014394605,0.94267786,0.0018040254,0.049829584,0.0003920279],"about_ca_topic_score_codex":0.00023890499,"about_ca_topic_score_gemma":0.000041029612,"teacher_disagreement_score":0.11682308,"about_ca_system_score_codex":0.0002605162,"about_ca_system_score_gemma":0.0013808634,"threshold_uncertainty_score":0.9999107},"labels":[],"label_agreement":null},{"id":"W4386396039","doi":"10.26434/chemrxiv-2023-09l28","title":"A “Neat” Synthesis of Substituted 2-Hydroxy-pyrido[1,2-a]pyrimidin-4-ones","year":2023,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; British Columbia Knowledge Development Fund; University of Victoria","keywords":"Diethyl malonate; Chemistry; Simple (philosophy); Organic chemistry; Condensation; Solvent; Malonate; Mathematics; Combinatorial chemistry; Catalysis; Thermodynamics; Philosophy","score_opus":0.044219294017557656,"score_gpt":0.27267198336629783,"score_spread":0.2284526893487402,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386396039","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9636897,0.0004894098,0.00013148061,0.0008394515,0.00027841236,0.00025331715,0.00020878697,0.00070538593,0.033404086],"genre_scores_gemma":[0.99476457,0.0005168247,0.00065554836,0.000013145062,0.0005232454,0.00089708925,0.00020248661,0.00016175816,0.002265337],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99708575,0.000024287154,0.0009078499,0.0010285293,0.0004452687,0.00050833763],"domain_scores_gemma":[0.9962751,0.00061639113,0.0006651769,0.002055491,0.0001985857,0.0001892188],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002908172,0.0005916272,0.001014989,0.00017699358,0.0001379043,0.00006843651,0.0011751342,0.0007915414,0.00134291],"category_scores_gemma":[0.0005720075,0.0006067705,0.0006145293,0.00029576782,0.00029930836,0.000053591848,0.00083721394,0.0006862812,0.00051090453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007232521,0.0009998173,0.0036334759,0.006801878,0.0011578016,0.000040270497,0.0004668893,0.0011290498,0.9692272,0.0049425974,0.0060284566,0.005500237],"study_design_scores_gemma":[0.00015967054,0.0000025192346,0.0018020045,0.0008693638,0.00034395698,0.000005316414,0.00016413897,0.0007070822,0.98933333,0.0024957643,0.0034763669,0.0006405017],"about_ca_topic_score_codex":0.00019085377,"about_ca_topic_score_gemma":0.000017404154,"teacher_disagreement_score":0.031138748,"about_ca_system_score_codex":0.00011479885,"about_ca_system_score_gemma":0.00024056544,"threshold_uncertainty_score":0.9996384},"labels":[],"label_agreement":null},{"id":"W4389225780","doi":"10.1002/slct.202303327","title":"Chemistry of 3,5‐Dichloro‐4 <i>H</i> ‐1,2,6‐thiadiazine‐4‐thione","year":2023,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Agricultural Research Institute; University of Cyprus; Ministry of Agriculture - Saskatchewan","keywords":"Chemistry; Medicinal chemistry; Stereochemistry; Thiopyran; Crystal structure; Organic chemistry","score_opus":0.01152388967331484,"score_gpt":0.23563412200992975,"score_spread":0.22411023233661492,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389225780","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82511336,0.00018931224,0.000023517669,0.00027591505,0.000022126114,0.00005014726,0.00007967772,0.00047365704,0.17377228],"genre_scores_gemma":[0.98760015,0.00016445496,0.00013032893,0.000026730248,0.00029682927,0.00011150768,0.00023643345,0.000054609704,0.011378969],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99828196,0.0000047737694,0.0004586332,0.00046011762,0.00032229268,0.00047219786],"domain_scores_gemma":[0.99858487,0.00016260956,0.0002069721,0.00075255625,0.00012696406,0.0001660509],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001698598,0.0002570831,0.00034979655,0.00003087064,0.000117054195,0.000021456526,0.0004934004,0.00023642945,0.0035233966],"category_scores_gemma":[0.00021136746,0.0002711923,0.00019412463,0.00071063155,0.00014884268,0.000047171612,0.00010543788,0.00026133156,0.00031418935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001362568,0.00008388775,0.00059154216,0.00045355363,0.000043886797,0.0000051997595,0.000050732255,0.000014565187,0.98652977,0.00006300473,0.009959868,0.0021903678],"study_design_scores_gemma":[0.0003261005,0.0000033818674,0.00012095172,0.000065850305,0.00003388651,0.000018561217,0.00011594742,0.00023971271,0.9704982,0.00029339615,0.028015723,0.00026827856],"about_ca_topic_score_codex":0.000013507263,"about_ca_topic_score_gemma":7.233377e-7,"teacher_disagreement_score":0.16248676,"about_ca_system_score_codex":0.000052688505,"about_ca_system_score_gemma":0.00012899355,"threshold_uncertainty_score":0.999974},"labels":[],"label_agreement":null},{"id":"W4389264772","doi":"10.3390/molecules28237912","title":"Synthesis and Biological Evaluation of 2-Substituted Quinazolin-4(3H)-Ones with Antiproliferative Activities","year":2023,"lang":"en","type":"article","venue":"Molecules","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Structural Genomics Consortium","keywords":"Potency; Chemistry; Selectivity; Kinase; Cell culture; Combinatorial chemistry; Stereochemistry; Biochemistry; In vitro; Biology","score_opus":0.04545935265570889,"score_gpt":0.285464446768308,"score_spread":0.24000509411259913,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389264772","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99543476,0.00014069887,0.00013849675,0.00020221654,0.000007635371,0.00010887759,0.000060915114,0.00009625739,0.0038101182],"genre_scores_gemma":[0.9991727,0.0001199712,0.00033569624,0.000007455536,0.000034165438,0.00024575146,0.00002714666,0.000013574304,0.000043525695],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991249,0.00004665869,0.00016064182,0.0002518863,0.00025769274,0.00015823796],"domain_scores_gemma":[0.9993022,0.0002543097,0.0000968844,0.0002018068,0.000104893006,0.00003990703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023217236,0.00013363465,0.00020841463,0.00006478272,0.00010815399,0.000022048202,0.00009095972,0.00008051703,0.00015737805],"category_scores_gemma":[0.00017359637,0.00009894565,0.000036291392,0.00018612252,0.0002177436,0.000055461136,0.000041159292,0.00006151654,0.000011131811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008280377,0.00013754958,0.007811584,0.000082608516,0.00011912333,0.0000047760464,0.0004168526,0.00018686721,0.96393514,0.0044809664,0.00007540047,0.02266634],"study_design_scores_gemma":[0.00024622752,0.000018656818,0.017682862,0.00007438935,0.0000943593,0.0000066189937,0.0011083657,0.0026720753,0.9770794,0.0007062334,0.00015003589,0.00016077276],"about_ca_topic_score_codex":0.00001977352,"about_ca_topic_score_gemma":0.000012641771,"teacher_disagreement_score":0.022505568,"about_ca_system_score_codex":0.000016520324,"about_ca_system_score_gemma":0.000050712475,"threshold_uncertainty_score":0.40348867},"labels":[],"label_agreement":null},{"id":"W4391215567","doi":"10.1139/cjc-2023-0150","title":"A “neat” synthesis of substituted 2-hydroxy-pyrido[1,2-a]pyrimidin-4-ones","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Diethyl malonate; Condensation; Organic chemistry; Combinatorial chemistry; Simple (philosophy); Malonate; Catalysis","score_opus":0.01040534451280646,"score_gpt":0.21613600417698728,"score_spread":0.20573065966418083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391215567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94576114,0.003741883,0.000044995144,0.000853584,0.00012408344,0.000026398415,0.0001872588,0.000025776046,0.049234908],"genre_scores_gemma":[0.99832344,0.00008690533,0.00015649242,0.000013469275,0.00049263187,0.000009683149,0.0000077941395,0.000037432037,0.00087213353],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986093,0.000008384526,0.0006251445,0.0002057519,0.00022250159,0.00032890643],"domain_scores_gemma":[0.9983844,0.00022497169,0.00023963492,0.00036016435,0.00019042807,0.00060038676],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020446852,0.00020219118,0.00037611744,0.00011100168,0.00009366591,0.00008666503,0.0004972481,0.00019255745,0.0038979652],"category_scores_gemma":[0.00031166186,0.00019224637,0.00030282405,0.00024982804,0.0002139834,0.00012425706,0.000014436602,0.0003523981,0.000028160845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012161752,0.000042560107,0.00067467755,0.0010089698,0.00026234073,0.00026678984,0.00023977012,0.00008236921,0.98699534,0.0004469435,0.0036126703,0.0063554086],"study_design_scores_gemma":[0.00009840458,0.0000034068555,0.00016465278,0.00073687144,0.00012895506,0.0004238691,0.00032485655,0.00011495938,0.9590077,0.0003049745,0.03849502,0.00019634527],"about_ca_topic_score_codex":0.0005107219,"about_ca_topic_score_gemma":0.00024045266,"teacher_disagreement_score":0.052562345,"about_ca_system_score_codex":0.00018413029,"about_ca_system_score_gemma":0.0017571643,"threshold_uncertainty_score":0.9970126},"labels":[],"label_agreement":null},{"id":"W4393951720","doi":"10.1164/rccm.202403-0574ed","title":"“A Mighty Flame Can Follow a Tiny Spark”: Is This the Case of c-Jun N-Terminal Kinase 1 Inhibitors in Idiopathic Pulmonary Fibrosis?","year":2024,"lang":"en","type":"letter","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Alberta Health Services","funders":"","keywords":"Medicine; Idiopathic pulmonary fibrosis; c-jun; Terminal (telecommunication); SPARK (programming language); Kinase; Pulmonary fibrosis; Cancer research; Internal medicine; Fibrosis; Lung; Cell biology; Telecommunications; Biochemistry; Gene; Engineering","score_opus":0.01590101760177368,"score_gpt":0.283186531350187,"score_spread":0.2672855137484133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393951720","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5695965,0.066886105,0.000007631039,0.3604339,0.00037143464,0.00018358187,0.00033334314,0.000024325873,0.002163182],"genre_scores_gemma":[0.9336417,0.00020839208,0.000032993707,0.061237972,0.0046715727,0.000029298106,0.000008027706,0.000060886287,0.00010920459],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969345,0.00025406416,0.0013127174,0.0004627125,0.0005974131,0.000438621],"domain_scores_gemma":[0.9973183,0.00093681813,0.0005560919,0.00053242856,0.00040377566,0.00025255687],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006387521,0.00045095364,0.0012141454,0.00028775737,0.00014191249,0.000039597497,0.00040725182,0.00034006586,0.00038017772],"category_scores_gemma":[0.0005377425,0.00028969508,0.00033851352,0.0004184427,0.0024088055,0.00006900497,0.00010426573,0.002918475,0.000003800352],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000496366,0.00027791294,0.0019160365,0.012393461,0.00035198973,0.23799197,0.010844405,8.9906996e-7,0.023225103,0.0002827975,0.4638166,0.24840245],"study_design_scores_gemma":[0.001075283,0.0030415994,0.00011315325,0.01749338,0.0023150549,0.024188703,0.028315395,0.000032122563,0.013198033,0.00078618375,0.90836275,0.0010783745],"about_ca_topic_score_codex":0.00036277508,"about_ca_topic_score_gemma":0.000038846036,"teacher_disagreement_score":0.4445461,"about_ca_system_score_codex":0.00012095579,"about_ca_system_score_gemma":0.00033916763,"threshold_uncertainty_score":0.99995553},"labels":[],"label_agreement":null},{"id":"W4399993798","doi":"10.1139/cjc-2024-0101","title":"A purification-free method for the synthesis of thiazolium salts using P <sub>2</sub> S <sub>5</sub> -Py <sub>2</sub> complex or P <sub>4</sub> S <sub>10</sub>","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Alliance de recherche numérique du Canada; Western Canada Research Grid","keywords":"Chemistry; Combinatorial chemistry; Organic chemistry","score_opus":0.03167374223613795,"score_gpt":0.26977948851628364,"score_spread":0.2381057462801457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399993798","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9792256,0.0036279054,0.005615664,0.004632313,0.0006028986,0.000996753,0.0030747564,0.00021605141,0.0020080972],"genre_scores_gemma":[0.9921678,0.001221128,0.0021982908,0.00045745834,0.0026632524,0.00049690297,0.00021812008,0.00047750896,0.00009954915],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9901597,0.00027680775,0.0036266947,0.0018793748,0.001558809,0.0024986225],"domain_scores_gemma":[0.98607457,0.00411674,0.0024783055,0.0032531612,0.0017553824,0.0023218314],"candidate_categories":["metaepi_narrow","sts","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0025495319,0.0017456358,0.0023044483,0.0007173285,0.0015252165,0.00085015805,0.0035110062,0.0014404682,0.00031583497],"category_scores_gemma":[0.0032284155,0.001614877,0.0019325266,0.0018171839,0.0010521186,0.0006674588,0.00031903564,0.0022595755,0.000088256296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028006214,0.00025886344,0.00005306629,0.0021802303,0.0011480605,0.00017000336,0.00043521245,0.0004916467,0.9110917,0.00019913646,0.021728817,0.06196324],"study_design_scores_gemma":[0.0013446407,0.00006220964,0.00021943352,0.0021942884,0.001751013,0.0009963425,0.0011148439,0.0039522885,0.9783014,0.0013035771,0.007176057,0.0015838718],"about_ca_topic_score_codex":0.00028822885,"about_ca_topic_score_gemma":0.0017458329,"teacher_disagreement_score":0.06720977,"about_ca_system_score_codex":0.0017547539,"about_ca_system_score_gemma":0.00756056,"threshold_uncertainty_score":0.9998559},"labels":[],"label_agreement":null},{"id":"W4402522710","doi":"10.1039/d4ra06025c","title":"Design and synthesis of novel main protease inhibitors of COVID-19: quinoxalino[2,1-<i>b</i>]quinazolin-12-ones","year":2024,"lang":"en","type":"article","venue":"RSC Advances","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Ferdowsi University of Mashhad; University of Ottawa","keywords":"Coronavirus disease 2019 (COVID-19); Protease; Chemistry; Combinatorial chemistry; Stereochemistry; Enzyme; Biochemistry; Medicine; Internal medicine","score_opus":0.024929703198288248,"score_gpt":0.2886958445693252,"score_spread":0.26376614137103693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402522710","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81603783,0.033171527,0.13698535,0.0034168032,0.00027701844,0.0015499784,0.0013118834,0.00061139656,0.00663821],"genre_scores_gemma":[0.9839726,0.0010473011,0.014164832,0.000035240675,0.00014532535,0.00031508505,0.000006887963,0.000040434308,0.00027229008],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984618,0.000034210534,0.0005385454,0.00045260318,0.0002646233,0.0002482114],"domain_scores_gemma":[0.99795246,0.001226548,0.00021571844,0.00036819855,0.000046965437,0.00019008988],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003526424,0.00023391903,0.0003940025,0.00010700456,0.00009810724,0.000029269644,0.00021958545,0.00011566966,0.00020547376],"category_scores_gemma":[0.00048630775,0.0002054434,0.000113510214,0.00020612912,0.0003229871,0.00018896331,0.000073131894,0.00012707424,0.000005834195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014203062,0.000654515,0.0005039723,0.005156042,0.00010969371,0.000014603723,0.00061981875,0.0010444861,0.9480133,0.0082561,0.00040851333,0.03507693],"study_design_scores_gemma":[0.00029853135,0.000034394994,0.000022545795,0.0005750093,0.00010163106,0.000025989691,0.0005505217,0.0015494821,0.9717409,0.0024786498,0.022350086,0.00027225516],"about_ca_topic_score_codex":0.00006136475,"about_ca_topic_score_gemma":0.000009250579,"teacher_disagreement_score":0.16793478,"about_ca_system_score_codex":0.000048191363,"about_ca_system_score_gemma":0.00023033764,"threshold_uncertainty_score":0.83777386},"labels":[],"label_agreement":null},{"id":"W4404120659","doi":"10.3389/fchem.2024.1498104","title":"New series of 4,6-diaryl pyrimidines: facile synthesis and antiproliferative activity as dual EGFR/VEGFR-2 inhibitors","year":2024,"lang":"en","type":"article","venue":"Frontiers in Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"University of Waterloo","keywords":"Lipophilicity; Chemistry; Erlotinib; Potency; Docking (animal); EGFR inhibitors; In vitro; Apoptosis; Pharmacology; Sorafenib; Stereochemistry; Cell culture; Lead compound; Cancer cell; Biochemistry; Combinatorial chemistry; Cancer; Cancer research; Epidermal growth factor receptor; Receptor; Biology; Medicine; Internal medicine","score_opus":0.007739559189154664,"score_gpt":0.22763438050706414,"score_spread":0.21989482131790947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404120659","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9801407,0.0022229082,0.00037696172,0.00057294325,0.00013640425,0.00008795506,0.00018734291,0.00012421906,0.016150596],"genre_scores_gemma":[0.9933796,0.00043826125,0.0018908565,0.0000065591066,0.00029269492,0.00008107537,0.00001621611,0.000038380163,0.003856377],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859786,0.00001229106,0.0003371924,0.00052592024,0.00021988538,0.00030687658],"domain_scores_gemma":[0.99922556,0.00014945676,0.000096388765,0.00034392474,0.00003246607,0.00015218889],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012703075,0.0002795482,0.00042064794,0.00005596359,0.000072900264,0.000073375195,0.00016673714,0.00026144955,0.00060305494],"category_scores_gemma":[0.00018187982,0.00028042114,0.00011516956,0.00023150937,0.00021016687,0.00023478628,0.00009646675,0.000307188,0.00000835836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009251868,0.000109896355,0.0053773485,0.0013509191,0.00013703378,0.000030379471,0.00063796167,0.000009624559,0.93730205,0.00011011576,0.017265458,0.037576698],"study_design_scores_gemma":[0.0001431748,0.0000063103607,0.00014995909,0.0003536988,0.000050659546,0.000028234452,0.0012559044,0.00026947414,0.98819417,0.0009010989,0.008369215,0.00027808346],"about_ca_topic_score_codex":0.000102864375,"about_ca_topic_score_gemma":0.000004730198,"teacher_disagreement_score":0.05089214,"about_ca_system_score_codex":0.00010909632,"about_ca_system_score_gemma":0.00024912937,"threshold_uncertainty_score":0.9999648},"labels":[],"label_agreement":null},{"id":"W4404453247","doi":"10.1016/j.ejmech.2024.117065","title":"Novel potent SOS1 inhibitors containing a tricyclic quinazoline scaffold: A joint view of experiments and simulations","year":2024,"lang":"en","type":"article","venue":"European Journal of Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Science Foundation of Hubei Province; National Natural Science Foundation of China","keywords":"Chemistry; Tricyclic; Quinazoline; Scaffold; Stereochemistry; Pharmacology; Combinatorial chemistry","score_opus":0.033181776399219695,"score_gpt":0.2800532128120895,"score_spread":0.2468714364128698,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404453247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97971106,0.009301026,0.0012821391,0.0006548696,0.00008491268,0.000047315665,0.000030564053,0.000030588464,0.008857546],"genre_scores_gemma":[0.99770457,0.00025917348,0.0008654175,0.00003715786,0.0008590616,0.0000018210771,0.000007877094,0.000041510004,0.0002234163],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981475,0.000029152887,0.000997554,0.00022079745,0.00040966403,0.00019531461],"domain_scores_gemma":[0.99883556,0.00014274693,0.00044454206,0.00021093992,0.00013619628,0.0002300392],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006032015,0.00020363895,0.00039695084,0.00007559607,0.000072995965,0.000039228355,0.00020051765,0.000046191835,0.00037679804],"category_scores_gemma":[0.00018248544,0.00016702745,0.00016800014,0.00016199792,0.00013831438,0.000082018836,0.00007930202,0.00035169287,0.0000046211503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042195985,0.0001658047,0.00006926749,0.00047688917,0.00011367953,0.00011633713,0.0005687197,0.000051650728,0.9761944,0.000027411983,0.0002620702,0.021911565],"study_design_scores_gemma":[0.0016858662,0.00013899762,0.00027046175,0.0038490358,0.00027935763,0.0012318254,0.0018944936,0.001320384,0.97319007,0.000041681888,0.015822992,0.00027480922],"about_ca_topic_score_codex":0.000003709478,"about_ca_topic_score_gemma":1.3525225e-7,"teacher_disagreement_score":0.021636756,"about_ca_system_score_codex":0.00006374547,"about_ca_system_score_gemma":0.000105635256,"threshold_uncertainty_score":0.6811182},"labels":[],"label_agreement":null},{"id":"W4405042939","doi":"10.1182/blood-2024-206347","title":"NF-Kb Pathway Activation Driven By TRAF3 Loss Mediates Resistance to Anti-BCMA T-Cell Based Therapies in Multiple Myeloma","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Multiple myeloma; Cancer research; NFKB1; Bortezomib; Medicine; Immunology; Biology; Transcription factor; Genetics; Gene","score_opus":0.009108858396391584,"score_gpt":0.21541059534385562,"score_spread":0.20630173694746404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405042939","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948267,0.0006698732,0.0002021151,0.0013519461,0.000023143679,0.00014182946,0.00019354714,0.00015630691,0.0024345608],"genre_scores_gemma":[0.9977629,0.000043658947,0.0007125884,0.00007784981,0.00011454692,0.00021203511,0.000082781364,0.000039709714,0.00095389446],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893844,0.000020062756,0.000244211,0.00038056023,0.0001788799,0.00023784333],"domain_scores_gemma":[0.9992295,0.00031302447,0.000048206,0.0003104558,0.000026971486,0.00007182841],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000092019094,0.00016801883,0.00017312939,0.00006548323,0.00007252693,0.000072559924,0.00020290507,0.00010606249,0.00021590904],"category_scores_gemma":[0.000046789544,0.00015929417,0.00006761529,0.0002437419,0.00003536167,0.000081393,0.000020696842,0.00014180392,0.00007309646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001284044,0.00049003516,0.0035910225,0.00015376732,0.000020518499,0.000008178448,0.000561231,0.000023933655,0.99232614,0.00009505214,0.00094257353,0.0017747261],"study_design_scores_gemma":[0.00058193394,0.000008469895,0.0022739791,0.00017142318,0.000015099191,4.566158e-7,0.00014362302,0.000328574,0.9722596,0.00010482504,0.023910709,0.00020130149],"about_ca_topic_score_codex":0.000025014646,"about_ca_topic_score_gemma":0.00007269785,"teacher_disagreement_score":0.022968136,"about_ca_system_score_codex":0.00003266862,"about_ca_system_score_gemma":0.000059618742,"threshold_uncertainty_score":0.6495828},"labels":[],"label_agreement":null},{"id":"W4406222005","doi":"10.1101/2025.01.08.631920","title":"Structure of mycobacterial NDH-2 bound to a 2-mercapto-quinazolinone inhibitor","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Quinazolinone; Chemistry; Cancer research; Medicine; Combinatorial chemistry","score_opus":0.009176823626350852,"score_gpt":0.22450417358214872,"score_spread":0.21532734995579786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406222005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99203604,0.00040429653,0.00021603747,0.00026363143,0.0010160984,0.0005695707,0.0050248294,0.00032357385,0.00014593788],"genre_scores_gemma":[0.9937415,0.0000801029,0.0038640536,0.0001124475,0.0017768604,0.00024767726,0.0000025282825,0.00012212108,0.000052716965],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962894,0.00005356427,0.0010665574,0.0013830065,0.00051794254,0.0006895348],"domain_scores_gemma":[0.9957177,0.00011567342,0.0006661939,0.0024608145,0.0006494691,0.00039011956],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020752383,0.00081598264,0.001108097,0.0003119567,0.00019287718,0.00020846451,0.0011515312,0.0010495215,0.0008380744],"category_scores_gemma":[0.00026214367,0.00090571254,0.00032448085,0.0005673734,0.00016301092,0.00009269047,0.0010940229,0.00090237235,0.00005468986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008377281,0.00021821207,0.00069166586,0.0012044986,0.000205776,0.000007002472,0.000018968558,0.00003618482,0.995424,0.0012700543,0.00083189755,0.000007972625],"study_design_scores_gemma":[0.00044772212,0.000020430778,0.004415197,0.0009255305,0.00022452818,1.3883848e-8,0.0000053372833,0.000030959407,0.9750304,0.000013353436,0.018064244,0.00082223734],"about_ca_topic_score_codex":0.00012068327,"about_ca_topic_score_gemma":0.000008424525,"teacher_disagreement_score":0.020393547,"about_ca_system_score_codex":0.0003317509,"about_ca_system_score_gemma":0.0010867584,"threshold_uncertainty_score":0.99933934},"labels":[],"label_agreement":null},{"id":"W4408722376","doi":"10.1021/acs.jmedchem.5c00049","title":"Structure of Mycobacterial NDH-2 Bound to a 2-Mercapto-Quinazolinone Inhibitor","year":2025,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Chemistry; Mycobacterium smegmatis; Quinazolinone; Mycobacterium tuberculosis; Cofactor; Biochemistry; Oxidoreductase; Enzyme; Flavin adenine dinucleotide; Active site; Dehydrogenase; Stereochemistry; Tuberculosis","score_opus":0.005406969456013344,"score_gpt":0.2556608305559487,"score_spread":0.25025386109993536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408722376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9897687,0.0005489404,0.0001168402,0.001232604,0.0002615621,0.00004752593,0.00006031083,0.000012596877,0.007950927],"genre_scores_gemma":[0.9963768,0.00004522038,0.00054467405,0.000117406715,0.0019221952,0.000003301992,0.000007266538,0.000017595152,0.00096551434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980399,0.000011536846,0.000962684,0.00021246629,0.00051367795,0.00025972503],"domain_scores_gemma":[0.9982632,0.0001396123,0.00059981894,0.0003781862,0.0003788031,0.00024042618],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020968945,0.0002229316,0.00058457087,0.000081640945,0.00007170289,0.000025632728,0.0004995043,0.00022794078,0.0020367217],"category_scores_gemma":[0.0003706552,0.00018837527,0.00020189988,0.00025936496,0.00013463348,0.00006542526,0.00008901178,0.0004890229,0.0000035879314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032696244,0.00014205469,0.0003953241,0.0004799635,0.00011449019,0.000016887625,0.0001317278,0.000008043259,0.98992246,0.00006688626,0.00508939,0.0033057895],"study_design_scores_gemma":[0.0010004259,0.000042520245,0.0004070266,0.00077489374,0.00017075568,0.0001427322,0.00049310765,0.0000054353804,0.9751837,0.0005301272,0.0211045,0.00014472775],"about_ca_topic_score_codex":0.000011344693,"about_ca_topic_score_gemma":0.0000017568884,"teacher_disagreement_score":0.01601511,"about_ca_system_score_codex":0.00013266585,"about_ca_system_score_gemma":0.00042443414,"threshold_uncertainty_score":0.99887556},"labels":[],"label_agreement":null},{"id":"W4410904782","doi":"10.5267/j.ccl.2025.3.005","title":"Synthesis of pyrrolo(pyrido)[1,2-a]quinazolinones and their benzoannulated analogues: An overview","year":2025,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Combinatorial chemistry; Stereochemistry","score_opus":0.026180025827395204,"score_gpt":0.2865231557216673,"score_spread":0.2603431298942721,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410904782","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911717,0.005876559,0.00008153428,0.0011141534,0.00005776729,0.000081602724,0.00019434844,0.000113237504,0.001309085],"genre_scores_gemma":[0.99826187,0.0011973794,0.00006158614,0.00007061937,0.00012860363,0.00010448355,0.00012282375,0.000025623258,0.000027015483],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99843174,0.000021778285,0.0005056946,0.00055928814,0.00014550475,0.0003360208],"domain_scores_gemma":[0.9985782,0.00022148267,0.00022304826,0.00076485565,0.00007944285,0.0001330052],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001388478,0.00034520647,0.00048348,0.0000556122,0.00013451064,0.000041908046,0.00044050592,0.00014744097,0.00037766338],"category_scores_gemma":[0.00009757298,0.0003143874,0.0001650793,0.00024844802,0.00027489313,0.000105584986,0.00012657474,0.0002566635,0.000005313014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021098182,0.00025797164,0.0016038845,0.0014782258,0.00009379079,0.0000011613605,0.00009902804,0.000015888107,0.9646351,0.00018864055,0.00048742615,0.0311178],"study_design_scores_gemma":[0.00026285564,0.0000013124143,0.0010778286,0.00058759446,0.00011890885,0.0000055737432,0.00020804265,0.00051251426,0.99028236,0.00023538178,0.0063945246,0.00031313332],"about_ca_topic_score_codex":0.000018181407,"about_ca_topic_score_gemma":0.0000017110324,"teacher_disagreement_score":0.030804668,"about_ca_system_score_codex":0.00004921874,"about_ca_system_score_gemma":0.000054615542,"threshold_uncertainty_score":0.9999308},"labels":[],"label_agreement":null},{"id":"W4411658456","doi":"10.51847/4xpxxtg","title":"10.51847/4XpxXtg","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Computer science","score_opus":0.006264046747519873,"score_gpt":0.1865611312008913,"score_spread":0.18029708445337142,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411658456","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008650782,0.000026128759,4.2953798e-7,0.00035297874,3.3496585e-7,0.000039822855,0.000023268934,0.00012916722,0.9907771],"genre_scores_gemma":[0.004082458,4.4047735e-7,0.00012186633,0.00003620842,0.0001436665,0.000048390175,0.000015613929,0.00001942563,0.9955319],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99941903,0.0000041891367,0.00012243778,0.00018121231,0.00009622762,0.00017687138],"domain_scores_gemma":[0.99947506,0.00003244986,0.000017279288,0.00035383267,0.000017588065,0.0001037924],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000038544305,0.00009126787,0.00010054532,0.00001611152,0.000070621274,0.000024161422,0.00018444745,0.000050784358,0.9989613],"category_scores_gemma":[0.00001093237,0.00009057263,0.00004936702,0.00008217176,0.000018208832,0.00002871454,0.000020196841,0.000057320303,0.98870707],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000132851765,0.00006227105,2.4205818e-7,0.0000056019785,0.000008468739,0.0000010778016,0.000006945668,0.000014773242,0.00758555,0.000007909206,0.025269106,0.96702474],"study_design_scores_gemma":[0.00007521366,0.0000069224247,0.000012474922,0.000009386266,0.000010274718,0.0000034968853,9.3861394e-7,0.0000771004,0.0053778905,0.000005851612,0.99429995,0.00012050574],"about_ca_topic_score_codex":0.000009276522,"about_ca_topic_score_gemma":4.3643194e-8,"teacher_disagreement_score":0.96903086,"about_ca_system_score_codex":0.0000187174,"about_ca_system_score_gemma":0.000013396653,"threshold_uncertainty_score":0.36934444},"labels":[],"label_agreement":null},{"id":"W4414196038","doi":"10.1002/slct.202503230","title":"Microwave Irradiation Mediated Synthesis of Quinazolinones Over Amberlyst‐15 Ion‐Exchange Resins","year":2025,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Catalysis; Quinazolinone; Selectivity; Lewis acids and bases; Microwave irradiation; Solid acid; Organic synthesis","score_opus":0.00780281737889695,"score_gpt":0.24213536993063658,"score_spread":0.23433255255173963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414196038","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84346557,0.0012844054,0.00010471827,0.00073527725,0.00006479876,0.0001651571,0.000228062,0.00020286356,0.15374912],"genre_scores_gemma":[0.99509126,0.00027158656,0.00023336135,0.00007818431,0.00019292941,0.00020612743,0.00015410714,0.000037833768,0.0037345905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998211,0.000022017439,0.0005825717,0.0005174637,0.00026469067,0.0004022596],"domain_scores_gemma":[0.9980425,0.00057868805,0.00032110274,0.00073790137,0.0001844453,0.00013534959],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00017687347,0.00030921696,0.00046409242,0.00008117549,0.00014439403,0.000035567264,0.00041381916,0.00033626755,0.002322211],"category_scores_gemma":[0.00086680194,0.00032363992,0.00020654208,0.00057621987,0.00013986322,0.00007165745,0.000079080564,0.00022793193,0.00003984038],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049669732,0.00021256719,0.0011906329,0.00065170584,0.00012058031,0.0000020622442,0.000068805064,0.000002780657,0.9806885,0.00036053316,0.011388152,0.005264025],"study_design_scores_gemma":[0.0003677091,0.0000053637714,0.002189738,0.00021167951,0.00013833803,0.0000047883746,0.00007552305,0.0001588888,0.98047733,0.00030344818,0.015789436,0.0002777246],"about_ca_topic_score_codex":0.000088755405,"about_ca_topic_score_gemma":0.0000376113,"teacher_disagreement_score":0.1516257,"about_ca_system_score_codex":0.00017120792,"about_ca_system_score_gemma":0.00027188502,"threshold_uncertainty_score":0.99992156},"labels":[],"label_agreement":null},{"id":"W4414239304","doi":"10.1021/acsmedchemlett.5c00237","title":"Quinazolinones as Bioisosteres of Naphthoquinones: A Path to Potent <i>Hs</i> DHODH Inhibitors with Optimized Properties","year":2025,"lang":"en","type":"article","venue":"ACS Medicinal Chemistry Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"National Institutes of Health; National Institute on Aging; Fundação Oswaldo Cruz; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Universidade Federal de Goiás; Fundação de Amparo à Pesquisa do Estado de Goiás; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Dihydroorotate dehydrogenase; Pyrimidine; Cytotoxicity; Potency; Pyrimidine metabolism; Enzyme; Drug discovery","score_opus":0.007830205489073637,"score_gpt":0.22372199689683406,"score_spread":0.2158917914077604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414239304","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9756714,0.00045495434,0.0003331364,0.01348288,0.000055292883,0.00024237481,0.000027914828,0.000121273915,0.009610782],"genre_scores_gemma":[0.9950517,0.00005838121,0.0012597883,0.0017791445,0.00024753684,0.00026823606,0.000029754541,0.000043454125,0.0012620377],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976591,0.000020726153,0.00065314607,0.0006341997,0.0005462026,0.00048662483],"domain_scores_gemma":[0.99844086,0.00012673772,0.00025346474,0.0007860617,0.00017268317,0.00022018602],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018630101,0.0004278455,0.0006090428,0.00008323081,0.00015017691,0.00004013768,0.0005619018,0.00016221472,0.00024700357],"category_scores_gemma":[0.00012693988,0.00032598246,0.0001385183,0.0004025318,0.00037575635,0.00007744198,0.00016410362,0.000291326,0.00002296781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004123535,0.00021458924,0.00034937935,0.001095434,0.00014900099,0.000034815956,0.0004975192,0.00006146653,0.991443,0.000036823152,0.0035778347,0.0021278053],"study_design_scores_gemma":[0.0011081457,0.00003506675,0.000045502322,0.0018001922,0.00016841128,0.000057682235,0.0017361369,0.00002104522,0.990035,0.000016791439,0.0046148705,0.0003611629],"about_ca_topic_score_codex":0.00022842662,"about_ca_topic_score_gemma":0.0000026540756,"teacher_disagreement_score":0.019380277,"about_ca_system_score_codex":0.00010226922,"about_ca_system_score_gemma":0.00018925613,"threshold_uncertainty_score":0.99991924},"labels":[],"label_agreement":null},{"id":"W4415187717","doi":"10.3390/molecules30204047","title":"Design, Characterization, and Hematopoietic Efficacy of a Fluorinated Pyrazolopiperidine Inclusion Complex","year":2025,"lang":"en","type":"article","venue":"Molecules","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lethbridge College","funders":"","keywords":"Haematopoiesis; In vivo; Solubility; Aqueous solution; In vitro; Dissolution; Drug","score_opus":0.01524765728820717,"score_gpt":0.2567282524393912,"score_spread":0.241480595151184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415187717","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9611997,0.00014240034,0.036346126,0.0007738672,0.000008999234,0.00009868117,0.000013677678,0.000055839442,0.001360707],"genre_scores_gemma":[0.99805725,0.000053883803,0.0013261925,0.000061581195,0.000010391251,0.000028737513,0.00006195774,0.000009652141,0.00039036004],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99942786,0.000012446263,0.00020913145,0.00017316308,0.00007832491,0.00009909486],"domain_scores_gemma":[0.99953365,0.00008995623,0.00007313065,0.0002160535,0.000059023387,0.000028197432],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000052755116,0.00009699971,0.00016259258,0.000048835915,0.00015677503,0.000013089694,0.00012285303,0.00005525786,0.00017959661],"category_scores_gemma":[0.000055353124,0.00009191847,0.000027097754,0.0001521221,0.000073564224,0.000020038357,0.0002430586,0.00004385806,0.0000033748256],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018764093,0.00010521865,0.00012852653,0.00011312252,0.000015705427,6.7366045e-7,0.00019128162,0.0000070276787,0.98930466,0.0034387344,0.000050745457,0.006625556],"study_design_scores_gemma":[0.00034325794,0.000007419417,0.0050447932,0.00009336292,0.000023925935,0.0000021074034,0.00002691389,0.0015678381,0.98818856,0.000485407,0.004128005,0.00008837487],"about_ca_topic_score_codex":0.0000063399857,"about_ca_topic_score_gemma":3.4729763e-7,"teacher_disagreement_score":0.03685754,"about_ca_system_score_codex":0.000012504409,"about_ca_system_score_gemma":0.000024575364,"threshold_uncertainty_score":0.37483266},"labels":[],"label_agreement":null},{"id":"W4415983508","doi":"10.5430/jst.v15n1p32","title":"Targeting integrin beta 1 using anti-tumorigenic quinazoline derivative in inhibition of glioblastoma cell invasion and survival: An in vitro preclinical study","year":2025,"lang":"","type":"article","venue":"Journal of Solid Tumors","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Uppsala Universitet; National Institutes of Health; West Virginia University","keywords":"Quinazoline; In vitro; Neuroblastoma; Cell; Matrigel; Cell culture; Cell growth","score_opus":0.028739736634025445,"score_gpt":0.3297664027783428,"score_spread":0.30102666614431733,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415983508","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980842,0.0006564717,0.00020865393,0.0002280579,0.0001739308,0.0004897705,0.000055692137,0.000008529109,0.00009472585],"genre_scores_gemma":[0.99846995,0.00033633833,0.0008667336,0.000020385593,0.00022930192,0.000011163775,0.0000067071423,0.000047408677,0.00001198963],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9937184,0.0005882446,0.0040059616,0.0006116785,0.0005448807,0.0005308648],"domain_scores_gemma":[0.9956154,0.00070364523,0.0025571699,0.00041774558,0.000492871,0.00021314502],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002932504,0.00048299588,0.0017219791,0.00087670604,0.00014160002,0.00006788928,0.00042067966,0.00027550463,0.00004339571],"category_scores_gemma":[0.0005975291,0.0004794959,0.00023826734,0.0011902653,0.00025737932,0.00044962115,0.00033729203,0.0015213097,7.718446e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011178259,0.0062237876,0.07054706,0.00047350506,0.00007956573,0.00016555395,0.0027641524,0.0020075433,0.91532886,0.000025292153,0.000004415288,0.0012624292],"study_design_scores_gemma":[0.0038413175,0.0006895345,0.043294907,0.0023915484,0.00020069585,0.000040911968,0.021587819,0.0067251152,0.9204469,0.00039808083,0.0000052723044,0.00037789714],"about_ca_topic_score_codex":0.00020371229,"about_ca_topic_score_gemma":0.00015881375,"teacher_disagreement_score":0.027252153,"about_ca_system_score_codex":0.00032127678,"about_ca_system_score_gemma":0.00065339095,"threshold_uncertainty_score":0.9997657},"labels":[],"label_agreement":null},{"id":"W6920841504","doi":"10.6084/m9.figshare.21622169","title":"Additional file 1 of Synthesis, biological evaluation, and computational studies of some novel quinazoline derivatives as anticancer agents","year":2022,"lang":"en","type":"article","venue":"Open MIND","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Spectrum (functional analysis); Mass spectrum; Spectral line; Proton NMR; Public figure; Broad spectrum","score_opus":0.13821468270438894,"score_gpt":0.3834099152896474,"score_spread":0.24519523258525847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920841504","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5627647,0.00021287626,0.000009038787,0.00030207206,0.000011771114,0.00024799665,0.42948714,0.0000019823076,0.006962407],"genre_scores_gemma":[0.967014,0.000025652993,0.013869902,0.000037965267,0.000050184895,0.0015134396,0.01692766,0.000010123619,0.000551064],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990335,0.00003710996,0.0003008151,0.0002387335,0.00029980924,0.00009003145],"domain_scores_gemma":[0.9972407,0.0021483013,0.0002668165,0.00012532106,0.00018943826,0.000029405126],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00019358749,0.00009031592,0.00023542196,0.000031317857,0.00017179546,0.000010846628,0.00022018551,0.000026469965,0.85870886],"category_scores_gemma":[0.0010378745,0.000082517196,0.000038754653,0.00009535736,0.00023465857,0.00006986408,0.00033908008,0.000060882056,0.000017777607],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032240772,0.003483713,0.0007456004,0.00016360717,0.0014041809,0.0000039583906,0.0022311101,0.0025806061,0.10352528,0.005125602,0.7383613,0.14205262],"study_design_scores_gemma":[0.0019610936,0.00024379673,0.026750369,0.0005627232,0.00027300924,0.0000522872,0.013139328,0.009095851,0.12673599,0.015564678,0.8047902,0.0008307074],"about_ca_topic_score_codex":0.0000059521994,"about_ca_topic_score_gemma":0.0000013838094,"teacher_disagreement_score":0.85869104,"about_ca_system_score_codex":0.000036735826,"about_ca_system_score_gemma":0.00016431819,"threshold_uncertainty_score":0.33649534},"labels":[],"label_agreement":null},{"id":"W6930420592","doi":"10.5281/zenodo.10090268","title":"FIGURE 3 in Molecular phylogeny and phylogeography of Holarctic species of Pluteus section Pluteus (Agaricales: Pluteaceae), with description of twelve new species","year":2014,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Holarctic; Phylogeography; Section (typography); Molecular phylogenetics; Phylogenetic tree; Taxonomy (biology)","score_opus":0.018539134095949688,"score_gpt":0.20261433998195255,"score_spread":0.18407520588600287,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930420592","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10066785,0.001524012,0.0065896655,0.00013257761,0.000052543568,0.0006916687,0.0008618635,0.0003169393,0.8891629],"genre_scores_gemma":[0.9048475,0.0013960281,0.0014844402,0.000016934873,0.00030126964,3.991357e-7,0.0011782,0.0030244647,0.08775076],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984228,0.00010761177,0.00041884437,0.00042691192,0.0003888152,0.00023504175],"domain_scores_gemma":[0.99854416,0.000029895475,0.00053165917,0.00055658334,0.00023625347,0.000101456164],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00021538018,0.00024176422,0.0004494443,0.0004967311,0.00014703571,0.00007698165,0.00052171503,0.00021575273,0.0117993625],"category_scores_gemma":[0.00015433595,0.00023751649,0.00009376517,0.00055789726,0.0004185632,0.000059208443,0.00028572095,0.00030003433,0.00006541093],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021374923,0.0005974581,0.00042537064,0.0027017766,0.000402383,0.000007931875,0.0013166682,0.00008811315,0.80286545,0.0042233113,0.17907779,0.008080031],"study_design_scores_gemma":[0.0008487132,0.00020451969,0.0034407484,0.0006988197,0.00010512637,0.000018644036,0.00047359677,0.000037596492,0.029355645,0.00014295196,0.9643628,0.00031083293],"about_ca_topic_score_codex":0.00017531314,"about_ca_topic_score_gemma":0.0000073015067,"teacher_disagreement_score":0.80417967,"about_ca_system_score_codex":0.000058013437,"about_ca_system_score_gemma":0.000010716052,"threshold_uncertainty_score":0.989104},"labels":[],"label_agreement":null},{"id":"W6958400962","doi":"10.6084/m9.figshare.28766914.v1","title":"Additional file 4 of Cannabis smoking is associated with persistent epigenome-wide disruptions despite smoking cessation","year":2025,"lang":"en","type":"article","venue":"Figshare","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Queen's University; University of British Columbia","funders":"","keywords":"Smoking cessation; MEDLINE; Smoking epidemiology; Cannabis; Cigarette smoking","score_opus":0.02121617530064586,"score_gpt":0.23775998784599922,"score_spread":0.21654381254535338,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6958400962","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0016865656,0.000036833764,0.0000022034674,0.00020407095,0.000004210192,0.00007196738,0.96938336,0.000057553483,0.028553246],"genre_scores_gemma":[0.21095312,7.3170685e-7,0.000057739067,0.00010876374,0.000032090975,0.0014617783,0.7814133,0.00001528308,0.0059571466],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991251,0.00001115849,0.0002239005,0.00024271662,0.0002065892,0.00019052117],"domain_scores_gemma":[0.9984894,0.0007427807,0.00023433918,0.00024537984,0.00024073028,0.000047408383],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000019032423,0.00013185939,0.00015567764,0.00006944106,0.00023984376,0.000038343107,0.00017171471,0.00010657052,0.9860253],"category_scores_gemma":[0.0013676496,0.00013114208,0.00013548837,0.00029322747,0.000016427715,0.000079348814,0.000055318036,0.00013411907,0.000086050175],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000002493159,0.00006557092,0.00025330108,0.00008397734,0.0001297024,0.0000010598624,0.00009174089,0.000035595232,0.000060059414,0.000011564371,0.99840254,0.0008624094],"study_design_scores_gemma":[0.00017081545,0.0000098462515,0.0219124,0.0054095592,0.000068020985,8.374016e-7,0.00028752343,0.0002606668,0.0022094364,0.00005736019,0.96940297,0.0002105388],"about_ca_topic_score_codex":0.000017056773,"about_ca_topic_score_gemma":0.000044353277,"teacher_disagreement_score":0.9859392,"about_ca_system_score_codex":0.00017421923,"about_ca_system_score_gemma":0.00016960224,"threshold_uncertainty_score":0.5347819},"labels":[],"label_agreement":null},{"id":"W6958775743","doi":"10.6084/m9.figshare.28953756","title":"Additional file 1 of Novel genetic association with migratory diapause in Australian monarch butterflies","year":2025,"lang":"en","type":"dataset","venue":"Figshare","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Association (psychology); Diapause; Genetic association; Genetic variation; Ectotherm; Identification (biology)","score_opus":0.020307186405217767,"score_gpt":0.2422344580153002,"score_spread":0.2219272716100824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6958775743","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000015164404,0.000019057741,7.562373e-9,0.00003438145,0.0000038849275,0.00009243931,0.99942404,0.00001483429,0.00039616725],"genre_scores_gemma":[0.000018902101,0.0000037313284,0.00013224747,0.000030919833,0.00012684728,0.0036465484,0.9913844,0.000011084926,0.0046453066],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988771,0.000010640736,0.00029404258,0.00030965023,0.00030145698,0.00020708462],"domain_scores_gemma":[0.99767303,0.0013543033,0.0003728542,0.00042882108,0.00012702752,0.00004395597],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00001230827,0.00021087712,0.00026915743,0.000104251514,0.00004135172,0.0000253238,0.00034305695,0.00036241725,0.98905134],"category_scores_gemma":[0.0010312567,0.00021253267,0.000073637646,0.0001775568,0.000009702475,0.00003264829,0.000082281,0.00035154793,0.0003110962],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000003870702,0.00017205732,0.000009432613,0.00067375164,0.000043087915,0.000003928077,0.000003997432,0.000009576421,0.000025082167,7.513858e-8,0.9989438,0.00011135932],"study_design_scores_gemma":[0.000120329016,0.0000064375645,0.0022818362,0.0058833,0.000021791007,0.0000013404881,0.000014316714,0.000006021376,0.00039401918,0.0000012222928,0.9910673,0.00020208431],"about_ca_topic_score_codex":0.000073186246,"about_ca_topic_score_gemma":0.0004415828,"teacher_disagreement_score":0.9887402,"about_ca_system_score_codex":0.00015636907,"about_ca_system_score_gemma":0.0003104582,"threshold_uncertainty_score":0.86668307},"labels":[],"label_agreement":null},{"id":"W6980519826","doi":"","title":"1910 Chap. 0409. An Act To Authorize The Fire District In The Town Of Dalton To Take Water From A Certain Brook In The Town Of Hinsdale.","year":2011,"lang":"en","type":"other","venue":"State Library's electronic repository (State Library of Massachusetts)","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Lake district; Urban district; Quarter (Canadian coin); Fire history","score_opus":0.010413153605123649,"score_gpt":0.21610301154351744,"score_spread":0.20568985793839378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6980519826","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6357572,0.002394317,0.000025256975,0.007826101,0.00018320882,0.0026845348,0.0029261918,0.00027897337,0.34792423],"genre_scores_gemma":[0.7798865,0.0010175386,0.0003939052,0.0006472112,0.00046192895,0.0006688987,0.0012121649,0.00068330846,0.21502857],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9943423,0.00070450944,0.0017205711,0.0011545947,0.0008299566,0.0012480164],"domain_scores_gemma":[0.9952594,0.0005731257,0.0009544349,0.0029836947,0.0000230791,0.00020628012],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004621903,0.00090343796,0.0012116698,0.000351407,0.000154149,0.00019248143,0.004197292,0.00041488584,0.0034134693],"category_scores_gemma":[0.000023236385,0.0005106862,0.00040917605,0.00080226944,0.0003170922,0.0008065678,0.00044909373,0.0012154173,0.000020411719],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036252756,0.005018508,0.012469658,0.0017455292,0.0014870455,0.0003067607,0.0750558,0.0002588996,0.120190084,0.004450722,0.74823976,0.027151944],"study_design_scores_gemma":[0.0008444428,0.0005615751,0.0035017838,0.0006569963,0.00015731387,0.000020606478,0.0011261668,0.00007167848,0.20448592,0.004429344,0.7831437,0.0010004912],"about_ca_topic_score_codex":0.0022528886,"about_ca_topic_score_gemma":0.00014503482,"teacher_disagreement_score":0.14412929,"about_ca_system_score_codex":0.00006458164,"about_ca_system_score_gemma":0.00049664447,"threshold_uncertainty_score":0.99973446},"labels":[],"label_agreement":null},{"id":"W7038555714","doi":"","title":"The impact of emotion regulation strategies and anxiety sensitivity on symptom severity in anxious children and adolescents","year":2025,"lang":"en","type":"preprint","venue":"","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Child, Adolescent and Family Mental Health","funders":"","keywords":"Anxiety; Sensitivity (control systems); Anxiety sensitivity; Affect (linguistics); Personality","score_opus":0.006522277727629759,"score_gpt":0.2591006992628458,"score_spread":0.25257842153521604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7038555714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963821,0.000075790565,0.00010066122,0.00007322062,0.0000114567465,0.00022321081,0.00013950076,0.000031972162,0.002962074],"genre_scores_gemma":[0.9990815,0.00065196416,0.000048111862,0.0000038920152,0.000041774743,0.000011739326,0.000072073286,0.0000071845197,0.00008173829],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990734,0.000062256535,0.00025003537,0.00036371438,0.00011585602,0.0001347243],"domain_scores_gemma":[0.9992409,0.000091790076,0.00016949701,0.00041212593,0.000050594364,0.000035142024],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025669934,0.00020046021,0.0002436932,0.000041908672,0.000096697695,0.00010303073,0.00007496072,0.00026473554,0.00000922549],"category_scores_gemma":[0.0000278048,0.00014594097,0.00007904252,0.000058077723,0.00009832667,0.000047287158,0.000202859,0.00033557529,3.3344145e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026527193,0.00075383065,0.73766637,0.00084299746,0.00027669306,8.4314865e-7,0.00069296535,0.0047705844,0.031784162,0.003675654,0.00023489597,0.21903574],"study_design_scores_gemma":[0.00019008733,0.000006715765,0.98599,0.00038869682,0.00002054944,0.0000035945088,0.00009821638,0.0051369895,0.0057744086,0.0022543261,0.000002491575,0.00013391246],"about_ca_topic_score_codex":0.0019941865,"about_ca_topic_score_gemma":0.00033561137,"teacher_disagreement_score":0.24832365,"about_ca_system_score_codex":0.000078856945,"about_ca_system_score_gemma":0.000105201696,"threshold_uncertainty_score":0.59512997},"labels":[],"label_agreement":null},{"id":"W7133030721","doi":"","title":"Application of carbamoylimidazolium salts in small molecule and combinatorial synthesis","year":2004,"lang":"","type":"dissertation","venue":"TSpace","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Nucleophile; Reactivity (psychology); Alkyl; Aldehyde; Selectivity; Aqueous solution; Carboxylic acid; Bicyclic molecule","score_opus":0.010296608136855007,"score_gpt":0.2787953633193054,"score_spread":0.26849875518245037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7133030721","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98057353,0.0013933125,0.0001973056,0.00026154928,0.00018045375,0.0007970961,0.00006446493,0.00005064667,0.016481636],"genre_scores_gemma":[0.9968906,0.0007560792,0.0002974764,0.000010115092,0.00020630997,0.0008605077,0.00028626565,0.0001254324,0.0005672212],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968682,0.00007165009,0.001085357,0.0010719431,0.00035512296,0.00054774777],"domain_scores_gemma":[0.99704826,0.00045187765,0.0010437503,0.0009948352,0.00024717933,0.00021409312],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003050133,0.0006795678,0.0010830861,0.0002589399,0.00015177582,0.0000549174,0.00050838944,0.0010195378,0.00015622815],"category_scores_gemma":[0.00026525577,0.00082713796,0.00021848953,0.0005058004,0.00019453876,0.000057727233,0.00009066173,0.0006119489,0.000032317177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006560285,0.0030303134,0.0022692203,0.0058588195,0.00025351063,0.000012020298,0.012102554,0.00021300006,0.9230225,0.036966015,0.000031345244,0.015584663],"study_design_scores_gemma":[0.0015985605,0.000045698052,0.004078033,0.0010997121,0.00041467787,0.000005846792,0.006952558,0.0009154383,0.9812493,0.0024030646,0.00034380454,0.000893341],"about_ca_topic_score_codex":0.005338066,"about_ca_topic_score_gemma":0.00081371726,"teacher_disagreement_score":0.058226753,"about_ca_system_score_codex":0.00029565152,"about_ca_system_score_gemma":0.000466892,"threshold_uncertainty_score":0.99941796},"labels":[],"label_agreement":null}]}